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Search of human proteins with 20270377
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20270377 DPY30 domain containing 1 [Homo sapiens]
(177 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20270377 DPY30 domain containing 1 [Homo sapiens] 342 8e-95
gi|14150195 DPY30 domain containing 2 [Homo sapiens] 83 1e-16
gi|148746195 trichohyalin [Homo sapiens] 51 6e-07
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens] 50 1e-06
gi|56549694 enabled homolog isoform a [Homo sapiens] 49 2e-06
gi|39930375 enabled homolog isoform b [Homo sapiens] 49 2e-06
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 48 4e-06
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 48 4e-06
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 48 4e-06
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 48 4e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 48 5e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 48 5e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 48 5e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 48 5e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 48 5e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 48 5e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 48 5e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 48 5e-06
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 47 9e-06
gi|221139761 zinc finger protein 853 [Homo sapiens] 47 1e-05
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 45 3e-05
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 45 3e-05
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 45 4e-05
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s... 45 4e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 44 6e-05
gi|224028248 non-POU domain containing, octamer-binding isoform ... 44 7e-05
gi|224028246 non-POU domain containing, octamer-binding isoform ... 44 7e-05
gi|224028244 non-POU domain containing, octamer-binding isoform ... 44 7e-05
gi|34932414 non-POU domain containing, octamer-binding isoform 1... 44 7e-05
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 44 7e-05
>gi|20270377 DPY30 domain containing 1 [Homo sapiens]
Length = 177
Score = 342 bits (878), Expect = 8e-95
Identities = 177/177 (100%), Positives = 177/177 (100%)
Query: 1 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 60
MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE
Sbjct: 1 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 60
Query: 61 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 120
RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM
Sbjct: 61 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 120
Query: 121 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL 177
ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL
Sbjct: 121 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL 177
>gi|14150195 DPY30 domain containing 2 [Homo sapiens]
Length = 177
Score = 83.2 bits (204), Expect = 1e-16
Identities = 49/153 (32%), Positives = 77/153 (50%), Gaps = 1/153 (0%)
Query: 1 MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERE 60
ME+ YL++ G CL Q LAEVA+VRP DPIEYLA W+Y Y++ ++ +++ L+ E
Sbjct: 1 METNYLKRCFGNCLAQALAEVAKVRPSDPIEYLAHWLYHYRKTAKAKEENREKKIHLQEE 60
Query: 61 RELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNM 120
+ +L E EM E LK EE +QQ EL + ++ +Q L KE +
Sbjct: 61 YDSSLKEMEMTEMLKQEEYQIQQNCEKCHKELTSETVSTKKTIFMQEDTNPLEKE-ALKQ 119
Query: 121 ENLVRNEDILHSEEATLDSGKTLAEISDRYGAP 153
E L ++ + ++ +I + P
Sbjct: 120 EFLPGTSSLIPGMPQQVPPSESAGQIDQNFKMP 152
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 50.8 bits (120), Expect = 6e-07
Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 7/102 (6%)
Query: 36 WIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQ 95
W+ + +E EQ R+K+ K ++E E +E +L+ EE QQ++ QL E +
Sbjct: 457 WLKREEETERHEQERRKQQLKRDQEEE----RRERWLKLEEEERREQQERREQQLRREQE 512
Query: 96 EKERQRI---QELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E+ QR+ +E +R Q++L E ++ E R E +L EE
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Score = 47.0 bits (110), Expect = 9e-06
Identities = 24/88 (27%), Positives = 51/88 (57%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E+ R+++ + E++ E+ ++L+ E+ ++QQL + E E +E++ +R QE +
Sbjct: 312 EERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEE 134
R ++QL +E ++ E +R E L E+
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQ 399
Score = 45.8 bits (107), Expect = 2e-05
Identities = 31/105 (29%), Positives = 57/105 (54%), Gaps = 6/105 (5%)
Query: 38 YKYKENVTMEQ---LRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEM 94
Y+ +E + E+ LR++ + +ERE E+E +++ + E+LL ++++ + ELE
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ-EEEQLLREEREKRRRQELER 1138
Query: 95 QEKERQRIQ--ELQRAQEQLGKEMRMNMENLVRNEDILHSEEATL 137
Q +E + +Q E Q +E+ K R +E R E+ L EE L
Sbjct: 1139 QYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQL 1183
Score = 45.1 bits (105), Expect = 3e-05
Identities = 40/109 (36%), Positives = 60/109 (55%), Gaps = 14/109 (12%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELE---MQ 95
KY+E E+L+Q+E L ERE ++ + K +EL +++QL L+ E E +Q
Sbjct: 989 KYREE---EELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL-LREEREKRRLQ 1044
Query: 96 EKERQ--RIQELQRAQEQ-LGKE----MRMNMENLVRNEDILHSEEATL 137
E+ERQ +ELQ+ +EQ LG+E R +E R E+ L EE L
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQL 1093
Score = 44.7 bits (104), Expect = 4e-05
Identities = 25/90 (27%), Positives = 52/90 (57%), Gaps = 2/90 (2%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERL--KAEELLLQQQQLALQLELEMQEKERQRIQE 104
+QLR+K+ + ++E +QE E+ + E+ L ++Q+ + +L +++E +R Q+
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
L+R QE+ +E ++ E +R E L E+
Sbjct: 364 LRREQEEERREQQLRREQQLRREQQLRREQ 393
Score = 44.3 bits (103), Expect = 6e-05
Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 16/114 (14%)
Query: 40 YKENVTMEQLR------QKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELE 93
Y + EQLR Q+E +L+RE QE + + EE L Q+++ L+ E E
Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE 949
Query: 94 ---MQEKERQ--RIQELQRAQEQL-----GKEMRMNMENLVRNEDILHSEEATL 137
QE+ERQ + ++LQ+ +EQL K R E R E+ L EE L
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003
Score = 44.3 bits (103), Expect = 6e-05
Identities = 38/109 (34%), Positives = 57/109 (52%), Gaps = 14/109 (12%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEM---Q 95
+Y+E E+L+Q+E L ERE QE+ + + EE L Q+++ L+ E E Q
Sbjct: 1049 QYREE---EELQQEEEQLLGEERETR-RRQELERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Query: 96 EKERQ--RIQELQRAQEQL-----GKEMRMNMENLVRNEDILHSEEATL 137
E+ERQ +ELQ+ +EQL K R +E R E+ + EE L
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Score = 43.5 bits (101), Expect = 1e-04
Identities = 27/88 (30%), Positives = 50/88 (56%), Gaps = 8/88 (9%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQLR+ E +L RER+ E++ +RL+ E+ L ++Q+ E +++E +R Q+ +
Sbjct: 276 EQLRKLERQELRRERQ---EEEQQQQRLRREQQLRRKQE-----EERREQQEERREQQER 327
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEE 134
R Q++ +E ++ E R E L E+
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQ 355
Score = 42.7 bits (99), Expect = 2e-04
Identities = 27/90 (30%), Positives = 53/90 (58%), Gaps = 3/90 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERL--KAEELLLQQQQLALQLELEMQEKERQRIQE 104
EQ ++E + RE++L ++E E+ + +E ++QQL + E E +E++ +R Q+
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
L+R ++QL +E ++ E +R E L E+
Sbjct: 383 LRR-EQQLRREQQLRREQQLRREQQLRREQ 411
Score = 42.0 bits (97), Expect = 3e-04
Identities = 38/112 (33%), Positives = 56/112 (50%), Gaps = 14/112 (12%)
Query: 36 WIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEM- 94
W +Y++ ++L+Q+E L ERE + QE + + EE L Q+++ L E E
Sbjct: 1016 WERQYRKK---DELQQEEEQLLREEREKRRL-QERERQYREEEELQQEEEQLLGEERETR 1071
Query: 95 --QEKERQ--RIQELQRAQEQL-----GKEMRMNMENLVRNEDILHSEEATL 137
QE ERQ + +ELQ+ +EQL K R E R E+ L EE L
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQL 1123
Score = 41.6 bits (96), Expect = 4e-04
Identities = 25/88 (28%), Positives = 50/88 (56%), Gaps = 2/88 (2%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E+ Q+E + + ER + +E ER + ++L +Q++ + +L +++E +R Q+L+
Sbjct: 320 ERREQQERREQQEERREQQLRREQEER-REQQLRREQEEERREQQLRREQEEERREQQLR 378
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEE 134
R Q QL +E ++ E +R E L E+
Sbjct: 379 REQ-QLRREQQLRREQQLRREQQLRREQ 405
Score = 40.8 bits (94), Expect = 6e-04
Identities = 27/96 (28%), Positives = 55/96 (57%), Gaps = 4/96 (4%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMM--ERLKAEELLLQQQQLALQLELEMQEKE 98
++ + EQ ++ +L RE+E EQ++ ++L+ E+ L ++QQL + +L +E++
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR-REQQ 406
Query: 99 RQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
+R Q+L+R Q QL +E ++ E + H +E
Sbjct: 407 LRREQQLRREQ-QLRREQQLRREQEEERHEQKHEQE 441
Score = 40.4 bits (93), Expect = 8e-04
Identities = 29/97 (29%), Positives = 57/97 (58%), Gaps = 6/97 (6%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEM---MERLKAEELLLQQQQLALQLELEMQEK 97
++ + EQ ++E +L RE+E EQ++ E + E+ L ++QQL + +L +E+
Sbjct: 336 EQQLRREQEERREQ-QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLR-REQ 393
Query: 98 ERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
+ +R Q+L+R ++QL +E ++ E +R E L E+
Sbjct: 394 QLRREQQLRR-EQQLRREQQLRREQQLRREQQLRREQ 429
Score = 40.0 bits (92), Expect = 0.001
Identities = 26/94 (27%), Positives = 50/94 (53%), Gaps = 6/94 (6%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEM-- 94
+ + +E E+ Q++ E E +L +E++ + R + EE +QQQ L+ E ++
Sbjct: 252 VLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEE---EQQQQRLRREQQLRR 308
Query: 95 -QEKERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
QE+ER+ QE +R Q++ ++ E +R E
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRRE 342
Score = 40.0 bits (92), Expect = 0.001
Identities = 33/118 (27%), Positives = 60/118 (50%), Gaps = 9/118 (7%)
Query: 49 LRQKEMAKLERERELALMEQEMMER----LKAEELLLQQQQLALQLELEMQEKERQRIQE 104
L+++E +LE+ER +++E ER LK EE +++Q L+ E E + ++R + +E
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREE---ERRQQRLKREQEERLEQRLKREE 606
Query: 105 LQRAQEQLGKEMRMNMENLV--RNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
++R +++ +E R+ E R + +L SEE + L L R EE
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Score = 39.7 bits (91), Expect = 0.001
Identities = 29/87 (33%), Positives = 50/87 (57%), Gaps = 5/87 (5%)
Query: 47 EQLRQKEMAKLERE--RELALMEQEMMERL--KAEELLLQQQQLALQLELE-MQEKERQR 101
EQLR++E+ +L R+ E +E +R+ + EE ++++ L+ E E +QE+E QR
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Query: 102 IQELQRAQEQLGKEMRMNMENLVRNED 128
+ELQ +EQL K R + + E+
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEE 294
Score = 39.7 bits (91), Expect = 0.001
Identities = 27/93 (29%), Positives = 50/93 (53%), Gaps = 5/93 (5%)
Query: 47 EQLRQKEMAKLERERELALMEQEMME----RLKAEELLLQQQQLALQLELEMQEKERQRI 102
++ R+ ++ K E ER +++E E RLK EE+ +Q+ + L+ +E E +R
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 103 QELQRAQEQ-LGKEMRMNMENLVRNEDILHSEE 134
Q+L +++EQ ++ ++ E R E L EE
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREE 663
Score = 38.5 bits (88), Expect = 0.003
Identities = 26/95 (27%), Positives = 52/95 (54%), Gaps = 7/95 (7%)
Query: 47 EQLRQKEMAKLERE--RELALMEQEMMER---LKAEELLLQQQQL--ALQLELEMQEKER 99
+QLR+++ + E++ RE L ++ + R L+ E+ L ++QQL QL E +E+
Sbjct: 375 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERH 434
Query: 100 QRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
++ E +R +++L +E + L R E+ E+
Sbjct: 435 EQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
Score = 38.1 bits (87), Expect = 0.004
Identities = 36/101 (35%), Positives = 51/101 (50%), Gaps = 11/101 (10%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEM---QEKERQ--R 101
++L+QKE L E E QE ++ + EE L Q+++ L+ E E QE ERQ +
Sbjct: 964 KKLQQKEEQLLGEEPEKR-RRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 102 IQELQRAQEQLGKEMR-----MNMENLVRNEDILHSEEATL 137
ELQ+ +EQL +E R E R E+ L EE L
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQL 1063
Score = 38.1 bits (87), Expect = 0.004
Identities = 28/88 (31%), Positives = 49/88 (55%), Gaps = 7/88 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E+L+Q+E L ERE QE+ + + EE + Q+++ +L +E E++R QEL+
Sbjct: 1114 EELQQEEEQLLREEREKR-RRQELERQYREEEEVQQEEE-----QLLREEPEKRRRQELE 1167
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEE 134
R Q + +E++ E L+R E +E
Sbjct: 1168 R-QYREEEELQQEEEQLLREEQEKRRQE 1194
Score = 37.7 bits (86), Expect = 0.005
Identities = 29/134 (21%), Positives = 66/134 (49%), Gaps = 9/134 (6%)
Query: 36 WIYKYKENVTMEQLRQKEMAKLERE--RELALMEQE----MMERLKAEELLLQQQQLALQ 89
W+ +E +Q R+++ + E+E RE L QE + +RL++E+ L ++Q+ +
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547
Query: 90 LELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
L+ +E++R E +R +++L +E + L++ E+ + + + L + R
Sbjct: 548 QLLKREEEKR---LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 150 YGAPNLSRVEELDE 163
L + E ++
Sbjct: 605 EEVERLEQEERREQ 618
Score = 37.7 bits (86), Expect = 0.005
Identities = 29/104 (27%), Positives = 51/104 (49%), Gaps = 18/104 (17%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E+ Q+ + ERE+EL +E+E + + LQ+++ LQ +++ER+R QE +
Sbjct: 815 EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ-----EDQERRRSQEQR 869
Query: 107 RAQE---QLGKEMRMN----------MENLVRNEDILHSEEATL 137
R Q+ QL +E + E L + + +L EE L
Sbjct: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913
Score = 37.0 bits (84), Expect = 0.009
Identities = 28/87 (32%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE ++ Q+E L ERE QE + + EE LLQ+++ + L QE++R+
Sbjct: 1305 KEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE---EQPLRRQERDRK 1361
Query: 101 RIQELQRAQEQLGKEMRMNMENLVRNE 127
+E R QEQ G++ + L R E
Sbjct: 1362 FREEELRHQEQ-GRKFLEEEQRLRRQE 1387
Score = 37.0 bits (84), Expect = 0.009
Identities = 20/77 (25%), Positives = 48/77 (62%), Gaps = 2/77 (2%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
+E +++ ++++ + ER+R+ EQ++ + + + L ++QQL Q ELE + +E +
Sbjct: 1671 EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQ-ELERKFREEE 1729
Query: 101 RIQELQRAQEQLGKEMR 117
++++ + QEQL ++ R
Sbjct: 1730 QLRQ-ETEQEQLRRQER 1745
Score = 36.6 bits (83), Expect = 0.012
Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQ--E 104
EQL ++E K R+ ++ + K E+LL ++ + + E E + +E + +Q E
Sbjct: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATL 137
Q +E+ K R E R +D L EE L
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033
Score = 36.6 bits (83), Expect = 0.012
Identities = 22/81 (27%), Positives = 42/81 (51%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E+ R++E+ + RE E E+E + R + E+ Q+ + + E E+Q++E Q ++E Q
Sbjct: 1129 EKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQ 1188
Query: 107 RAQEQLGKEMRMNMENLVRNE 127
+ Q + E L R +
Sbjct: 1189 EKRRQERERQYREEEELQRQK 1209
Score = 36.6 bits (83), Expect = 0.012
Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 13/97 (13%)
Query: 39 KYKENVTMEQLRQKE-MAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEK 97
K++E + Q R+++ +++ ER+R+ L EQ++ + + + + +QQL Q E Q++
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQ---EGQQQ 1612
Query: 98 ERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
RQ R EQL +E R E LH +E
Sbjct: 1613 LRQERDRKFREDEQLLQE---------REEQQLHRQE 1640
Score = 36.2 bits (82), Expect = 0.015
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
+QLR++E + RE E L QE + EE L++Q+L + E Q ++ ++L+
Sbjct: 1682 QQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEE 134
R QE+ K + R E L +E
Sbjct: 1742 R-QERYRKILEEEQLRPEREEQQLRRQE 1768
Score = 35.4 bits (80), Expect = 0.026
Identities = 26/83 (31%), Positives = 45/83 (54%), Gaps = 3/83 (3%)
Query: 47 EQLRQKEMAKLERERELALM--EQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE 104
+QLR+++ + E+E E EQE E+ E ++ L + E E E+ER++ Q+
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK-QQ 475
Query: 105 LQRAQEQLGKEMRMNMENLVRNE 127
L+R QE+ +E + +E R E
Sbjct: 476 LKRDQEEERRERWLKLEEEERRE 498
Score = 35.4 bits (80), Expect = 0.026
Identities = 32/114 (28%), Positives = 58/114 (50%), Gaps = 9/114 (7%)
Query: 37 IYKYKENVTMEQLRQKEMAKLE---RERELALMEQEMM--ERLKAEELLLQQQQLALQLE 91
+ K +E ++L++++ +LE + E+ +EQE +RLK EE +++Q L+ E
Sbjct: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 92 LEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAE 145
E+E +R Q+L+R Q++ ++ E R E L E + LAE
Sbjct: 638 ----EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Score = 35.0 bits (79), Expect = 0.034
Identities = 34/109 (31%), Positives = 52/109 (47%), Gaps = 21/109 (19%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELE------------- 93
EQL+++E A+ +E E L E + ER +++E + Q+ QLE E
Sbjct: 838 EQLQRRERAQQLQEEEDGLQEDQ--ERRRSQEQR-RDQKWRWQLEEERKRRRHTLYAKPA 894
Query: 94 MQEKERQRIQELQRAQEQLGKE-----MRMNMENLVRNEDILHSEEATL 137
+QE+ R+ Q LQ +E+L +E R E R E+ L EE L
Sbjct: 895 LQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQL 943
Score = 35.0 bits (79), Expect = 0.034
Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 9/93 (9%)
Query: 47 EQLRQKEMAKLER-ERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQEL 105
EQL ++E K R E E E+E +++ + E+LL ++ + + ELE Q +E +EL
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQ-EEEQLLREEPEKRRRQELERQYREE---EEL 1176
Query: 106 QRAQEQLGKE----MRMNMENLVRNEDILHSEE 134
Q+ +EQL +E R E R E+ L ++
Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEELQRQK 1209
Score = 35.0 bits (79), Expect = 0.034
Identities = 25/106 (23%), Positives = 53/106 (50%), Gaps = 12/106 (11%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ--------- 89
K++E + Q R+++ +ER+ +E+E R + + ++Q+L Q
Sbjct: 1462 KFREEEQLLQEREEQQLH-RQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEE 1520
Query: 90 -LELEMQEKERQRIQELQRAQEQ-LGKEMRMNMENLVRNEDILHSE 133
+L Q+++R+ +QE Q+ + Q G++ R + + R E+ L E
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE 1566
Score = 34.7 bits (78), Expect = 0.044
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 8/99 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEM-MERLKAEELLLQQQQLALQLELEMQEKE- 98
+E +EQ ++E + RE+ELA EQE ER+K+ + + Q L+ E + ++ +
Sbjct: 663 EEEERLEQRLKREHEEERREQELAEEEQEQARERIKSR---IPKWQWQLESEADARQSKV 719
Query: 99 --RQRIQELQ-RAQEQLGKEMRMNMENLVRNEDILHSEE 134
R R QE Q R QEQ K R E + E+ H ++
Sbjct: 720 YSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQ 758
Score = 34.3 bits (77), Expect = 0.058
Identities = 28/104 (26%), Positives = 51/104 (49%), Gaps = 17/104 (16%)
Query: 39 KYKENVTMEQLRQKEMAKLER--------ERELALMEQEMMERLKAEELLLQQQQLALQL 90
K++E + Q R+++ + ++ E +L L EQE +RL+ E + +Q +
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE--QRLRQE----RDRQYRAEE 1849
Query: 91 ELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
+ QEK R+ QEL + +EQ + R E +R E I ++
Sbjct: 1850 QFATQEKSRREEQELWQEEEQ---KRRQERERKLREEHIRRQQK 1890
Score = 33.9 bits (76), Expect = 0.076
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E+ Q+E +L RE QE+ + + EE L Q+++ L+ E E + +ER+R
Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER---QY 1199
Query: 107 RAQEQLGKEMRMNMENLVRNED 128
R +E+L ++ R + R+ED
Sbjct: 1200 REEEELQRQKR---KQRYRDED 1218
Score = 33.9 bits (76), Expect = 0.076
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELE--MQEKERQRIQE 104
+QL ++E + RE E + QE + EE L+Q++ E E +QE+E Q++
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHR 1480
Query: 105 LQRAQEQLGKEMRMNMENLVR--NEDILHSEE 134
+R ++ L +E ++ + R E L S+E
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Score = 33.5 bits (75), Expect = 0.099
Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 10/92 (10%)
Query: 47 EQLRQKEMAKLEREREL--ALMEQEMMERLKAEELLLQQQQLALQ--------LELEMQE 96
+QLRQ+ K E +L EQ++ + + + L ++QQL Q EL QE
Sbjct: 1453 QQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQE 1512
Query: 97 KERQRIQELQRAQEQLGKEMRMNMENLVRNED 128
ER+ ++E Q+ Q + + E +R ++
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544
Score = 33.1 bits (74), Expect = 0.13
Identities = 28/78 (35%), Positives = 46/78 (58%), Gaps = 12/78 (15%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLE------LEMQEKERQ 100
+++ Q+E K R+RE L ++E E+L+ EE Q+Q LQ E LE QE R+
Sbjct: 235 DRVFQEEEEKEWRKRETVLRKEE--EKLQEEE---PQRQRELQEEEEQLRKLERQELRRE 289
Query: 101 RIQELQRAQEQLGKEMRM 118
R QE ++ Q++L +E ++
Sbjct: 290 R-QEEEQQQQRLRREQQL 306
Score = 33.1 bits (74), Expect = 0.13
Identities = 25/87 (28%), Positives = 48/87 (55%), Gaps = 4/87 (4%)
Query: 39 KYKENVTMEQLR-QKEMAKLER-ERELALMEQEMMERLKAEELLLQQQQLALQLELEM-- 94
+Y++ + EQLR ++E +L R ER+ E+E + + + E+ L Q+ E E
Sbjct: 1745 RYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR 1804
Query: 95 QEKERQRIQELQRAQEQLGKEMRMNME 121
QE+E Q+++ QR + +E ++ +E
Sbjct: 1805 QEREEQQLRPQQRDGKYRWEEEQLQLE 1831
Score = 32.3 bits (72), Expect = 0.22
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 20/113 (17%)
Query: 42 ENVTMEQLRQKEMAKLERERELALMEQEMMER--LKAEELLLQ------------QQQLA 87
E + +Q R ++ + R+ EL QE ER +AEE LQ ++QL
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 88 LQLELEMQEKERQRIQELQRA------QEQLGKEMRMNMENLVRNEDILHSEE 134
+ LE++ K R+ Q+ +R QE+ KE R L + E+ L EE
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEE 264
Score = 32.3 bits (72), Expect = 0.22
Identities = 22/75 (29%), Positives = 40/75 (53%), Gaps = 6/75 (8%)
Query: 42 ENVTMEQLRQKEMAKLERERELALMEQEMME-RLKAEELLLQQQQLALQLELEMQEKERQ 100
E +QL + E + R+++L +QE E RLK EE ++ L+ L+ + +E +
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE-----EEERLEQRLKREHEEER 680
Query: 101 RIQELQRAQEQLGKE 115
R QEL +++ +E
Sbjct: 681 REQELAEEEQEQARE 695
Score = 32.3 bits (72), Expect = 0.22
Identities = 20/91 (21%), Positives = 45/91 (49%), Gaps = 11/91 (12%)
Query: 48 QLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ-----------LELEMQE 96
+ R++E+ E ER+ EQ++ + + + L ++QQL Q + +E
Sbjct: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEE 1561
Query: 97 KERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
+ RQ +E Q ++++ ++ R+ + + R E
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592
Score = 32.3 bits (72), Expect = 0.22
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 11/85 (12%)
Query: 41 KENVTMEQLRQKEMAK--LERER------ELALMEQEMMERLKAEELLLQQQQLALQLEL 92
++ EQLR++E + LE E+ E L QE + + EE L Q+++ + +L
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQERE---EQQL 1788
Query: 93 EMQEKERQRIQELQRAQEQLGKEMR 117
QE +R+ +E Q QE+ +++R
Sbjct: 1789 RSQESDRKFREEEQLRQEREEQQLR 1813
Score = 32.0 bits (71), Expect = 0.29
Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 3/82 (3%)
Query: 42 ENVTMEQLRQKEMAKLE--RERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKER 99
E + E+ R++ + + E ER L++ E E + ++L ++QQ + L+ +E+E
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL-RREQQERREQRLKREEEEE 666
Query: 100 QRIQELQRAQEQLGKEMRMNME 121
+ Q L+R E+ +E + E
Sbjct: 667 RLEQRLKREHEEERREQELAEE 688
Score = 32.0 bits (71), Expect = 0.29
Identities = 20/70 (28%), Positives = 42/70 (60%), Gaps = 1/70 (1%)
Query: 47 EQLRQKE-MAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQEL 105
+QLR++E +L +ER+ E E + + + E+ L +Q++ LE E Q + ++R Q+L
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
Query: 106 QRAQEQLGKE 115
+ +++ +E
Sbjct: 1662 RHDRDRKFRE 1671
Score = 32.0 bits (71), Expect = 0.29
Identities = 32/98 (32%), Positives = 47/98 (47%), Gaps = 11/98 (11%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQ---QQQLALQ------LELEMQEK 97
+QLR++E + + E L QE+ + + EE L Q Q+QL Q LE E
Sbjct: 1698 QQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP 1757
Query: 98 ERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEA 135
ER+ Q+L+R QE+ K R E L S+E+
Sbjct: 1758 EREE-QQLRR-QERDRKFREEEQLRQEREEQQLRSQES 1793
Score = 31.6 bits (70), Expect = 0.38
Identities = 26/85 (30%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
Query: 45 TMEQLR-QKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ-RI 102
+ EQ R QK +LE ER+ + + +E L ++QQL + E E+Q +ER+ R
Sbjct: 865 SQEQRRDQKWRWQLEEERKRR--RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRR 922
Query: 103 QELQRAQEQLGKEMRMNMENLVRNE 127
++ Q Q + ++++ E L+R E
Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREE 947
Score = 31.6 bits (70), Expect = 0.38
Identities = 21/95 (22%), Positives = 49/95 (51%), Gaps = 7/95 (7%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE + +++ + +R+R+ EQ++ + + + ++QQ + QE+ER+
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ------VRRQERERK 1447
Query: 101 RIQELQRAQEQLGKEMRMNMENL-VRNEDILHSEE 134
++E Q+ +++ ++ R + L R E LH +E
Sbjct: 1448 FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Score = 31.2 bits (69), Expect = 0.49
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 7/95 (7%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQ----LALQLELEM 94
K + T + R++E +L +ERE + ++ +R EE L Q+Q L + L
Sbjct: 1328 KRRRQETDRKFREEE--QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR 1385
Query: 95 QEKERQRIQELQRAQ-EQLGKEMRMNMENLVRNED 128
QE+ER+ ++E Q+ + ++ +++R + + R E+
Sbjct: 1386 QERERKFLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Score = 31.2 bits (69), Expect = 0.49
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 7/72 (9%)
Query: 47 EQLRQKEMAK-------LERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKER 99
+QLRQ+ K L+ E L QE + EE L++Q+ QL + K R
Sbjct: 1611 QQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFR 1670
Query: 100 QRIQELQRAQEQ 111
+ Q LQ +EQ
Sbjct: 1671 EEEQLLQEGEEQ 1682
Score = 31.2 bits (69), Expect = 0.49
Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 3/84 (3%)
Query: 50 RQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQ 109
RQ+ +L +R+ E+E + + E+ L +Q++ E E Q + ++R ++ + +
Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEE 1713
Query: 110 EQLGKEMRMNMENLVRNEDILHSE 133
+QL R +E R E+ L E
Sbjct: 1714 QQL---RRQELERKFREEEQLRQE 1734
Score = 31.2 bits (69), Expect = 0.49
Identities = 24/97 (24%), Positives = 49/97 (50%), Gaps = 8/97 (8%)
Query: 38 YKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEK 97
++ +E Q R+++ + E++ L QE+ + + EE L Q+ + Q +L QE+
Sbjct: 1693 FREEEQQLRRQERERKFLQEEQQ----LRRQELERKFREEEQLRQETE---QEQLRRQER 1745
Query: 98 ERQRIQELQRAQEQLGKEM-RMNMENLVRNEDILHSE 133
R+ ++E Q E+ +++ R + R E+ L E
Sbjct: 1746 YRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE 1782
Score = 30.8 bits (68), Expect = 0.64
Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 3/68 (4%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E+ +Q+E L E E ++ ER K + L +++QL + + ++E +QE Q
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Query: 107 ---RAQEQ 111
R+QEQ
Sbjct: 861 ERRRSQEQ 868
Score = 30.4 bits (67), Expect = 0.84
Identities = 21/76 (27%), Positives = 42/76 (55%), Gaps = 4/76 (5%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
+E +QLR+++ + E+ + E+ + +RLK E ++++ +L E QE+ R+
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH---EEERREQELAEEEQEQARE 695
Query: 101 RIQ-ELQRAQEQLGKE 115
RI+ + + Q QL E
Sbjct: 696 RIKSRIPKWQWQLESE 711
Score = 30.0 bits (66), Expect = 1.1
Identities = 20/59 (33%), Positives = 35/59 (59%), Gaps = 3/59 (5%)
Query: 50 RQKEMAKLERERELALMEQ--EMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
+++ + E+ERELA E+ E ERL+ + + ++L Q + E QE+E +R +E Q
Sbjct: 135 QRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQ-EWQEREERRAEEEQ 192
Score = 28.5 bits (62), Expect = 3.2
Identities = 23/89 (25%), Positives = 44/89 (49%), Gaps = 9/89 (10%)
Query: 36 WIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMER--LKAEELLLQQQQLALQLELE 93
W + K ++L + + +RER+L E++ E+ L EE Q+++ + E E
Sbjct: 771 WQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830
Query: 94 MQEKE-------RQRIQELQRAQEQLGKE 115
+Q E R+R Q+LQ ++ L ++
Sbjct: 831 LQFLEEEEQLQRRERAQQLQEEEDGLQED 859
Score = 28.5 bits (62), Expect = 3.2
Identities = 25/105 (23%), Positives = 47/105 (44%), Gaps = 22/105 (20%)
Query: 37 IYKYKENVTMEQLRQKEMAKLER----ERELALMEQEMMERLKAEELLLQQQQLALQLEL 92
+ + +E + E+ ++ +LER E EL EE LL+++Q + E
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQ----------EEEQLLREEQEKRRQER 1195
Query: 93 EMQEKERQRIQELQRAQEQLGKEMRMNM--------ENLVRNEDI 129
E Q +E + +Q +R Q ++ R ++ EN VR+ +
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV 1240
Score = 28.5 bits (62), Expect = 3.2
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 10/105 (9%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQ---------QLALQ 89
K +EN QL ++ + +++L + E ER + +E QQ QL +
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302
Query: 90 LELEMQEKERQRIQELQRAQEQL-GKEMRMNMENLVRNEDILHSE 133
+ E + ++R+ +E Q +E+ K R + R E+ L E
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE 1347
Score = 28.5 bits (62), Expect = 3.2
Identities = 19/97 (19%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Query: 39 KYKENVTMEQLRQKE-MAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEK 97
K++E+ + Q R+++ + + ER+R+ E ++ + + ++L + + + E +QE
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG 1679
Query: 98 ERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E Q+++ +R ++ +E ++ + R L E+
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQE--RERKFLQEEQ 1714
Score = 28.1 bits (61), Expect = 4.2
Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQ---LALQLELEMQEKER-QRI 102
EQL ++E K +ERE E+E ++R K ++ + Q L Q E E + R ++
Sbjct: 1181 EQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKV 1240
Query: 103 QELQRAQEQLGKEMRMNMENLVRNEDILH 131
R EQ + + + +D+ H
Sbjct: 1241 YCKGRENEQFRQLEDSQLRDRQSQQDLQH 1269
Score = 27.3 bits (59), Expect = 7.1
Identities = 26/95 (27%), Positives = 47/95 (49%), Gaps = 12/95 (12%)
Query: 48 QLRQKEMAKLERERELAL--MEQEMMERLKAEELLLQQQQLALQLELEMQEKE------R 99
Q + +E ++ R+R A + ++ +L+AEE +QQ + E +EKE R
Sbjct: 770 QWQAEEKSERGRQRLSARPPLREQRERQLRAEE----RQQREQRFLPEEEEKEQRRRQRR 825
Query: 100 QRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
+R +ELQ +E+ + R + L ED L ++
Sbjct: 826 EREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Score = 27.3 bits (59), Expect = 7.1
Identities = 20/83 (24%), Positives = 43/83 (51%), Gaps = 12/83 (14%)
Query: 40 YKENVTMEQLRQKEMAKLER--ERELALMEQEMMERLKAEEL---LLQQQQLALQLELEM 94
+ E +E+ QKE + +R + E L+ +E E+ + +E +++QL +
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL-------L 1345
Query: 95 QEKERQRIQELQRAQEQLGKEMR 117
QE+E Q ++ +R ++ +E+R
Sbjct: 1346 QEREEQPLRRQERDRKFREEELR 1368
>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
Length = 231
Score = 49.7 bits (117), Expect = 1e-06
Identities = 30/107 (28%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Query: 46 MEQLRQK-EMAKLERERELALMEQEMMERLKAEELL--LQQQQLALQLELEMQEKERQRI 102
M+ +++K +M KL++E + EQ ++ +AE+ L+++Q ALQ +L+ E E ++
Sbjct: 1 MDAIKKKMQMLKLDKENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKY 60
Query: 103 QELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
E ++A ++ + M++ +++E+ + +E L K +AE SDR
Sbjct: 61 SESEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDR 107
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 48.9 bits (115), Expect = 2e-06
Identities = 37/87 (42%), Positives = 52/87 (59%), Gaps = 10/87 (11%)
Query: 47 EQLRQKEMAK--LERERELALMEQEMMERLKAEELLLQQQQLAL-QLELEMQEKERQ--- 100
EQ RQKE+ + LERER ME+E +ER + E L++++L QLE E QE+ERQ
Sbjct: 149 EQQRQKELERERLERER----MERERLERERLERERLERERLEQEQLERERQERERQERL 204
Query: 101 RIQELQRAQEQLGKEMRMNMENLVRNE 127
QE QE+L ++ R++ E R E
Sbjct: 205 ERQERLERQERLERQERLDRERQERQE 231
Score = 45.4 bits (106), Expect = 3e-05
Identities = 30/86 (34%), Positives = 55/86 (63%), Gaps = 10/86 (11%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ--LELEMQEK- 97
+E + E+L Q++ LERER+ E+E ERL+ +E L +Q++L Q L+ E QE+
Sbjct: 178 RERLERERLEQEQ---LERERQ----ERERQERLERQERLERQERLERQERLDRERQERQ 230
Query: 98 ERQRIQELQRAQEQLGKEMRMNMENL 123
ER+R++ L+R +++ ++ ++ E L
Sbjct: 231 ERERLERLERERQERERQEQLEREQL 256
Score = 40.8 bits (94), Expect = 6e-04
Identities = 26/80 (32%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ-EMMERLKAEELLLQQQQLALQLELEMQEKER 99
+E + E+ ++ +LER+ L E+ E ERL E Q+++ +LE E QE+ER
Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERER 247
Query: 100 QRIQELQRAQEQLGKEMRMN 119
Q ++L+R Q + +E R++
Sbjct: 248 Q--EQLEREQLEWERERRIS 265
Score = 34.3 bits (77), Expect = 0.058
Identities = 21/72 (29%), Positives = 35/72 (48%)
Query: 48 QLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQR 107
Q R + +LER+ L QE ER + E L ++Q+ Q +LE ++ E +R + +
Sbjct: 207 QERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISS 266
Query: 108 AQEQLGKEMRMN 119
A E +N
Sbjct: 267 AAAPASVETPLN 278
Score = 31.6 bits (70), Expect = 0.38
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 72 ERLKAEELLLQQQQLALQLELEMQEKERQRIQELQR---AQEQLGKEMRMNMENLVRNED 128
E L+ + LQ+QQ +LE E E+ER + L+R +E+L +E R+ E L R
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERE-RLEQEQLERERQ 196
Query: 129 ILHSEE 134
+E
Sbjct: 197 ERERQE 202
Score = 29.6 bits (65), Expect = 1.4
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 77 EELLLQQQQL---ALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSE 133
EEL +Q++QL Q ELE + ER+R++ + +E+L +E R+ E L ++ L E
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERERMERERLERERLERE-RLERERL--EQEQLERE 194
Query: 134 EATLDSGKTLAEISDRYGAPNLSRVEELD 162
+ + L L R E LD
Sbjct: 195 RQERERQERLERQERLERQERLERQERLD 223
Score = 28.1 bits (61), Expect = 4.2
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 16/84 (19%)
Query: 60 ERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQR--------AQEQ 111
+ EL + +++ E+ + +EL ++ LE E E+ER + L+R QEQ
Sbjct: 137 QEELEIQRRQLQEQQRQKELERER------LERERMERERLERERLERERLERERLEQEQ 190
Query: 112 LGKEM--RMNMENLVRNEDILHSE 133
L +E R E L R E + E
Sbjct: 191 LERERQERERQERLERQERLERQE 214
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 48.9 bits (115), Expect = 2e-06
Identities = 37/87 (42%), Positives = 52/87 (59%), Gaps = 10/87 (11%)
Query: 47 EQLRQKEMAK--LERERELALMEQEMMERLKAEELLLQQQQLAL-QLELEMQEKERQ--- 100
EQ RQKE+ + LERER ME+E +ER + E L++++L QLE E QE+ERQ
Sbjct: 149 EQQRQKELERERLERER----MERERLERERLERERLERERLEQEQLERERQERERQERL 204
Query: 101 RIQELQRAQEQLGKEMRMNMENLVRNE 127
QE QE+L ++ R++ E R E
Sbjct: 205 ERQERLERQERLERQERLDRERQERQE 231
Score = 45.4 bits (106), Expect = 3e-05
Identities = 30/86 (34%), Positives = 55/86 (63%), Gaps = 10/86 (11%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ--LELEMQEK- 97
+E + E+L Q++ LERER+ E+E ERL+ +E L +Q++L Q L+ E QE+
Sbjct: 178 RERLERERLEQEQ---LERERQ----ERERQERLERQERLERQERLERQERLDRERQERQ 230
Query: 98 ERQRIQELQRAQEQLGKEMRMNMENL 123
ER+R++ L+R +++ ++ ++ E L
Sbjct: 231 ERERLERLERERQERERQEQLEREQL 256
Score = 40.8 bits (94), Expect = 6e-04
Identities = 26/80 (32%), Positives = 46/80 (57%), Gaps = 3/80 (3%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ-EMMERLKAEELLLQQQQLALQLELEMQEKER 99
+E + E+ ++ +LER+ L E+ E ERL E Q+++ +LE E QE+ER
Sbjct: 188 QEQLERERQERERQERLERQERLERQERLERQERLDRERQERQERERLERLERERQERER 247
Query: 100 QRIQELQRAQEQLGKEMRMN 119
Q ++L+R Q + +E R++
Sbjct: 248 Q--EQLEREQLEWERERRIS 265
Score = 34.3 bits (77), Expect = 0.058
Identities = 21/72 (29%), Positives = 35/72 (48%)
Query: 48 QLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQR 107
Q R + +LER+ L QE ER + E L ++Q+ Q +LE ++ E +R + +
Sbjct: 207 QERLERQERLERQERLDRERQERQERERLERLERERQERERQEQLEREQLEWERERRISS 266
Query: 108 AQEQLGKEMRMN 119
A E +N
Sbjct: 267 AAAPASVETPLN 278
Score = 31.6 bits (70), Expect = 0.38
Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 72 ERLKAEELLLQQQQLALQLELEMQEKERQRIQELQR---AQEQLGKEMRMNMENLVRNED 128
E L+ + LQ+QQ +LE E E+ER + L+R +E+L +E R+ E L R
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERE-RLEQEQLERERQ 196
Query: 129 ILHSEE 134
+E
Sbjct: 197 ERERQE 202
Score = 29.6 bits (65), Expect = 1.4
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 77 EELLLQQQQL---ALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSE 133
EEL +Q++QL Q ELE + ER+R++ + +E+L +E R+ E L ++ L E
Sbjct: 138 EELEIQRRQLQEQQRQKELERERLERERMERERLERERLERE-RLERERL--EQEQLERE 194
Query: 134 EATLDSGKTLAEISDRYGAPNLSRVEELD 162
+ + L L R E LD
Sbjct: 195 RQERERQERLERQERLERQERLERQERLD 223
Score = 28.1 bits (61), Expect = 4.2
Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 16/84 (19%)
Query: 60 ERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQR--------AQEQ 111
+ EL + +++ E+ + +EL ++ LE E E+ER + L+R QEQ
Sbjct: 137 QEELEIQRRQLQEQQRQKELERER------LERERMERERLERERLERERLERERLEQEQ 190
Query: 112 LGKEM--RMNMENLVRNEDILHSE 133
L +E R E L R E + E
Sbjct: 191 LERERQERERQERLERQERLERQE 214
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 48.1 bits (113), Expect = 4e-06
Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 6/122 (4%)
Query: 41 KENVTMEQLR--QKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE 98
+E E+LR Q+E+ + ++E E E+E + R K EE L +Q++ + L + +E+E
Sbjct: 747 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 806
Query: 99 RQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
RQ+ +E R E E R E + E++L +E E + R N R+
Sbjct: 807 RQQQEEALRRLE----ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 862
Query: 159 EE 160
EE
Sbjct: 863 EE 864
Score = 41.2 bits (95), Expect = 5e-04
Identities = 35/120 (29%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query: 46 MEQLRQKEMAKLERERELALM--EQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQ 103
++QL + + AKLE+ER A M ++E ER + EEL QQ+++ L+ + E + K R+ +
Sbjct: 720 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-LRRQQEEERKRREEEE 778
Query: 104 ELQRAQEQL---GKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
+R QE+ +E + + E+ EEA + E +R L R +E
Sbjct: 779 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 838
Score = 38.9 bits (89), Expect = 0.002
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 7/98 (7%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE 98
K +E + + +Q+E + +RE+E+AL Q + EE Q++ L E +E+E
Sbjct: 772 KRREEEELARRKQEEALRRQREQEIALRRQR-----EEEERQQQEEALRRLEERRREEEE 826
Query: 99 RQRIQELQRAQEQLGKEMRMNMENLVR--NEDILHSEE 134
R++ +EL R QE+ + E R E+ L EE
Sbjct: 827 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 864
Score = 34.3 bits (77), Expect = 0.058
Identities = 20/65 (30%), Positives = 40/65 (61%), Gaps = 4/65 (6%)
Query: 64 ALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENL 123
AL + + +E+ KA +L +Q++ ++ + +E+ER+R +EL+R QE++ + R E
Sbjct: 716 ALEQLQQLEKAKAAKL--EQERREAEMRAKREEEERKRQEELRRQQEEILR--RQQEEER 771
Query: 124 VRNED 128
R E+
Sbjct: 772 KRREE 776
Score = 33.9 bits (76), Expect = 0.076
Identities = 21/85 (24%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQE 96
+ + +E + R++E A+ E ME+E RL+ EE ++++L +Q + E+
Sbjct: 833 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA-RLRHEEEERKRKELEVQRQKELMR 891
Query: 97 KERQRIQELQRAQEQLGKEMRMNME 121
+ +Q+ + L+R Q+Q ++ M+
Sbjct: 892 QRQQQQEALRRLQQQQQQQQLAQMK 916
Score = 33.9 bits (76), Expect = 0.076
Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 16/75 (21%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ----------------LELEMQE 96
E+ KLE ERE L E++ ++ + + L QQQQ Q LE+Q+
Sbjct: 942 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1001
Query: 97 KERQRIQELQRAQEQ 111
+E +++Q+ Q+ Q+Q
Sbjct: 1002 EEARQMQKQQQQQQQ 1016
Score = 30.0 bits (66), Expect = 1.1
Identities = 20/75 (26%), Positives = 45/75 (60%), Gaps = 7/75 (9%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQ---LALQLELEMQEKERQRIQELQRAQ 109
+ +L R++EL + Q M+ L+ ++ L+QQQ LA Q + + +++Q++ L +
Sbjct: 600 DQERLTRQQELTALYQ--MQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 657
Query: 110 EQLGKEMRMNMENLV 124
+ L +MR++ +N++
Sbjct: 658 QTL--KMRISDQNII 670
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 48.1 bits (113), Expect = 4e-06
Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 6/122 (4%)
Query: 41 KENVTMEQLR--QKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE 98
+E E+LR Q+E+ + ++E E E+E + R K EE L +Q++ + L + +E+E
Sbjct: 774 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 833
Query: 99 RQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
RQ+ +E R E E R E + E++L +E E + R N R+
Sbjct: 834 RQQQEEALRRLE----ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 889
Query: 159 EE 160
EE
Sbjct: 890 EE 891
Score = 41.2 bits (95), Expect = 5e-04
Identities = 35/120 (29%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query: 46 MEQLRQKEMAKLERERELALM--EQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQ 103
++QL + + AKLE+ER A M ++E ER + EEL QQ+++ L+ + E + K R+ +
Sbjct: 747 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-LRRQQEEERKRREEEE 805
Query: 104 ELQRAQEQL---GKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
+R QE+ +E + + E+ EEA + E +R L R +E
Sbjct: 806 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 865
Score = 38.9 bits (89), Expect = 0.002
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 7/98 (7%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE 98
K +E + + +Q+E + +RE+E+AL Q + EE Q++ L E +E+E
Sbjct: 799 KRREEEELARRKQEEALRRQREQEIALRRQR-----EEEERQQQEEALRRLEERRREEEE 853
Query: 99 RQRIQELQRAQEQLGKEMRMNMENLVR--NEDILHSEE 134
R++ +EL R QE+ + E R E+ L EE
Sbjct: 854 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 891
Score = 34.3 bits (77), Expect = 0.058
Identities = 20/65 (30%), Positives = 40/65 (61%), Gaps = 4/65 (6%)
Query: 64 ALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENL 123
AL + + +E+ KA +L +Q++ ++ + +E+ER+R +EL+R QE++ + R E
Sbjct: 743 ALEQLQQLEKAKAAKL--EQERREAEMRAKREEEERKRQEELRRQQEEILR--RQQEEER 798
Query: 124 VRNED 128
R E+
Sbjct: 799 KRREE 803
Score = 33.9 bits (76), Expect = 0.076
Identities = 21/85 (24%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQE 96
+ + +E + R++E A+ E ME+E RL+ EE ++++L +Q + E+
Sbjct: 860 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA-RLRHEEEERKRKELEVQRQKELMR 918
Query: 97 KERQRIQELQRAQEQLGKEMRMNME 121
+ +Q+ + L+R Q+Q ++ M+
Sbjct: 919 QRQQQQEALRRLQQQQQQQQLAQMK 943
Score = 33.9 bits (76), Expect = 0.076
Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 16/75 (21%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ----------------LELEMQE 96
E+ KLE ERE L E++ ++ + + L QQQQ Q LE+Q+
Sbjct: 969 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1028
Query: 97 KERQRIQELQRAQEQ 111
+E +++Q+ Q+ Q+Q
Sbjct: 1029 EEARQMQKQQQQQQQ 1043
Score = 30.0 bits (66), Expect = 1.1
Identities = 20/75 (26%), Positives = 45/75 (60%), Gaps = 7/75 (9%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQ---LALQLELEMQEKERQRIQELQRAQ 109
+ +L R++EL + Q M+ L+ ++ L+QQQ LA Q + + +++Q++ L +
Sbjct: 627 DQERLTRQQELTALYQ--MQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 684
Query: 110 EQLGKEMRMNMENLV 124
+ L +MR++ +N++
Sbjct: 685 QTL--KMRISDQNII 697
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 48.1 bits (113), Expect = 4e-06
Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 6/122 (4%)
Query: 41 KENVTMEQLR--QKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE 98
+E E+LR Q+E+ + ++E E E+E + R K EE L +Q++ + L + +E+E
Sbjct: 753 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 812
Query: 99 RQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
RQ+ +E R E E R E + E++L +E E + R N R+
Sbjct: 813 RQQQEEALRRLE----ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 868
Query: 159 EE 160
EE
Sbjct: 869 EE 870
Score = 41.2 bits (95), Expect = 5e-04
Identities = 35/120 (29%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query: 46 MEQLRQKEMAKLERERELALM--EQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQ 103
++QL + + AKLE+ER A M ++E ER + EEL QQ+++ L+ + E + K R+ +
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-LRRQQEEERKRREEEE 784
Query: 104 ELQRAQEQL---GKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
+R QE+ +E + + E+ EEA + E +R L R +E
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Score = 38.9 bits (89), Expect = 0.002
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 7/98 (7%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE 98
K +E + + +Q+E + +RE+E+AL Q + EE Q++ L E +E+E
Sbjct: 778 KRREEEELARRKQEEALRRQREQEIALRRQR-----EEEERQQQEEALRRLEERRREEEE 832
Query: 99 RQRIQELQRAQEQLGKEMRMNMENLVR--NEDILHSEE 134
R++ +EL R QE+ + E R E+ L EE
Sbjct: 833 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 870
Score = 34.3 bits (77), Expect = 0.058
Identities = 20/65 (30%), Positives = 40/65 (61%), Gaps = 4/65 (6%)
Query: 64 ALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENL 123
AL + + +E+ KA +L +Q++ ++ + +E+ER+R +EL+R QE++ + R E
Sbjct: 722 ALEQLQQLEKAKAAKL--EQERREAEMRAKREEEERKRQEELRRQQEEILR--RQQEEER 777
Query: 124 VRNED 128
R E+
Sbjct: 778 KRREE 782
Score = 33.9 bits (76), Expect = 0.076
Identities = 21/85 (24%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQE 96
+ + +E + R++E A+ E ME+E RL+ EE ++++L +Q + E+
Sbjct: 839 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA-RLRHEEEERKRKELEVQRQKELMR 897
Query: 97 KERQRIQELQRAQEQLGKEMRMNME 121
+ +Q+ + L+R Q+Q ++ M+
Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMK 922
Score = 33.9 bits (76), Expect = 0.076
Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 16/75 (21%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ----------------LELEMQE 96
E+ KLE ERE L E++ ++ + + L QQQQ Q LE+Q+
Sbjct: 948 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007
Query: 97 KERQRIQELQRAQEQ 111
+E +++Q+ Q+ Q+Q
Sbjct: 1008 EEARQMQKQQQQQQQ 1022
Score = 30.0 bits (66), Expect = 1.1
Identities = 20/75 (26%), Positives = 45/75 (60%), Gaps = 7/75 (9%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQ---LALQLELEMQEKERQRIQELQRAQ 109
+ +L R++EL + Q M+ L+ ++ L+QQQ LA Q + + +++Q++ L +
Sbjct: 606 DQERLTRQQELTALYQ--MQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
Query: 110 EQLGKEMRMNMENLV 124
+ L +MR++ +N++
Sbjct: 664 QTL--KMRISDQNII 676
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 48.1 bits (113), Expect = 4e-06
Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 6/122 (4%)
Query: 41 KENVTMEQLR--QKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE 98
+E E+LR Q+E+ + ++E E E+E + R K EE L +Q++ + L + +E+E
Sbjct: 753 EERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEE 812
Query: 99 RQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
RQ+ +E R E E R E + E++L +E E + R N R+
Sbjct: 813 RQQQEEALRRLE----ERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRM 868
Query: 159 EE 160
EE
Sbjct: 869 EE 870
Score = 41.2 bits (95), Expect = 5e-04
Identities = 35/120 (29%), Positives = 60/120 (50%), Gaps = 6/120 (5%)
Query: 46 MEQLRQKEMAKLERERELALM--EQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQ 103
++QL + + AKLE+ER A M ++E ER + EEL QQ+++ L+ + E + K R+ +
Sbjct: 726 LQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEI-LRRQQEEERKRREEEE 784
Query: 104 ELQRAQEQL---GKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
+R QE+ +E + + E+ EEA + E +R L R +E
Sbjct: 785 LARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQE 844
Score = 38.9 bits (89), Expect = 0.002
Identities = 29/98 (29%), Positives = 49/98 (50%), Gaps = 7/98 (7%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE 98
K +E + + +Q+E + +RE+E+AL Q + EE Q++ L E +E+E
Sbjct: 778 KRREEEELARRKQEEALRRQREQEIALRRQR-----EEEERQQQEEALRRLEERRREEEE 832
Query: 99 RQRIQELQRAQEQLGKEMRMNMENLVR--NEDILHSEE 134
R++ +EL R QE+ + E R E+ L EE
Sbjct: 833 RRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 870
Score = 34.3 bits (77), Expect = 0.058
Identities = 20/65 (30%), Positives = 40/65 (61%), Gaps = 4/65 (6%)
Query: 64 ALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENL 123
AL + + +E+ KA +L +Q++ ++ + +E+ER+R +EL+R QE++ + R E
Sbjct: 722 ALEQLQQLEKAKAAKL--EQERREAEMRAKREEEERKRQEELRRQQEEILR--RQQEEER 777
Query: 124 VRNED 128
R E+
Sbjct: 778 KRREE 782
Score = 33.9 bits (76), Expect = 0.076
Identities = 21/85 (24%), Positives = 46/85 (54%), Gaps = 1/85 (1%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQE 96
+ + +E + R++E A+ E ME+E RL+ EE ++++L +Q + E+
Sbjct: 839 LLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAA-RLRHEEEERKRKELEVQRQKELMR 897
Query: 97 KERQRIQELQRAQEQLGKEMRMNME 121
+ +Q+ + L+R Q+Q ++ M+
Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMK 922
Score = 33.9 bits (76), Expect = 0.076
Identities = 23/75 (30%), Positives = 39/75 (52%), Gaps = 16/75 (21%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ----------------LELEMQE 96
E+ KLE ERE L E++ ++ + + L QQQQ Q LE+Q+
Sbjct: 948 EIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQ 1007
Query: 97 KERQRIQELQRAQEQ 111
+E +++Q+ Q+ Q+Q
Sbjct: 1008 EEARQMQKQQQQQQQ 1022
Score = 30.0 bits (66), Expect = 1.1
Identities = 20/75 (26%), Positives = 45/75 (60%), Gaps = 7/75 (9%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQ---LALQLELEMQEKERQRIQELQRAQ 109
+ +L R++EL + Q M+ L+ ++ L+QQQ LA Q + + +++Q++ L +
Sbjct: 606 DQERLTRQQELTALYQ--MQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQLALLLQQF 663
Query: 110 EQLGKEMRMNMENLV 124
+ L +MR++ +N++
Sbjct: 664 QTL--KMRISDQNII 676
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 47.8 bits (112), Expect = 5e-06
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ RQ++ + ER+R +A ME+ + +AEE + ++Q+ QLE + +++E +E Q
Sbjct: 2533 EQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQ 2592
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEA---TLDSGK 141
R +EQL + L +E++ S+ A TL +G+
Sbjct: 2593 RLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2630
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 7/127 (5%)
Query: 16 QGLAEVARVRPVDPIEYLALWIYKYKENVTM-----EQLRQKEMAKLERERELALMEQEM 70
Q AE R R E L W K E + + E +QK +A+ E E++ E+E
Sbjct: 1615 QQQAEAERAREEAERE-LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA 1673
Query: 71 MERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
R KAEE ++Q++LA Q ELE Q + + + + A EQ +R E + +L
Sbjct: 1674 RRRGKAEEQAVRQRELAEQ-ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLL 1732
Query: 131 HSEEATL 137
E A L
Sbjct: 1733 EEELARL 1739
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-- 104
+ +RQ+E+A+ E E++ L E +RL AE Q+ + L+ E E E++RQ ++E
Sbjct: 1682 QAVRQRELAEQELEKQRQLAEGTAQQRLAAE-----QELIRLRAETEQGEQQRQLLEEEL 1736
Query: 105 --LQR---AQEQLGKEMRMNMENL-VRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
LQR A Q +E+ + + E +L S+ + ++ +E S + R
Sbjct: 1737 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 159 EELDE 163
EL E
Sbjct: 1797 RELAE 1801
Score = 37.0 bits (84), Expect = 0.009
Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE +E RQ+++A E ER E+ + + L AEE +Q++ AL+ ++ K +
Sbjct: 1962 KEQAELEAARQRQLAA-EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2020
Query: 101 RIQELQRAQEQLGKEMRMNME 121
+ +RA+++ +++++ E
Sbjct: 2021 ARRLRERAEQESARQLQLAQE 2041
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/93 (30%), Positives = 56/93 (60%), Gaps = 8/93 (8%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQL--ELEMQEKERQRIQE 104
E+LR++ + +R+R+ E E+ R+KAE +++Q ALQ EL +Q +E +R
Sbjct: 1497 ERLRRQVQDESQRKRQA---EVELASRVKAEAEAAREKQRALQALEELRLQAEEAER--R 1551
Query: 105 LQRAQEQLGKEMRMNMENLVRN-EDILHSEEAT 136
L++A+ + +++++ +E R+ E L S+ A+
Sbjct: 1552 LRQAEVERARQVQVALETAQRSAEAELQSKRAS 1584
Score = 35.4 bits (80), Expect = 0.026
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ----EMMERLKAE-ELLLQQQQLALQLELEMQ 95
+E + QL ++++A+ E L E+ + RLKAE ELL QQ++LA + +Q
Sbjct: 2288 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2347
Query: 96 EKERQRIQELQRAQEQLGKEMRMNME 121
E + Q Q+L A+E G + + E
Sbjct: 2348 EDKEQMAQQL--AEETQGFQRTLEAE 2371
Score = 34.7 bits (78), Expect = 0.044
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ + + A+ E+ EQE R +AE+ L+Q+Q A E+E +K ++ +
Sbjct: 2123 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQ-AADAEMEKHKKFAEQTLRQK 2181
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
EQ +R+ +E +++L E L + T A A S+VEE
Sbjct: 2182 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-------ARQRSQVEE 2228
Score = 34.3 bits (77), Expect = 0.058
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEE----LLLQQQQLALQLELEMQ------- 95
E R +E A+ E R+L L ++ +RL+AEE +QQ++ LQ L+ +
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079
Query: 96 ----EKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E R+ +E + A+ Q +E + + E + S E
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122
Score = 34.3 bits (77), Expect = 0.058
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 35 LWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEEL-LLQQQQLALQLELE 93
L I + + + E+LR+ +A+LERE+E E ++++ LK+EE+ +QQ+QL + +
Sbjct: 2434 LEIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQ-LKSEEMQTVQQEQLLQETQAL 2491
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
Q ++ LQR E+ ++ + +E L ++E
Sbjct: 2492 QQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2523
Score = 32.7 bits (73), Expect = 0.17
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 28/127 (22%)
Query: 39 KYKENVTMEQLRQKEMAKLEREREL---------------ALMEQEM---MERLKAEELL 80
K ++ + QL+ +EM +++E+ L +L+++E E+ K E+L
Sbjct: 2461 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2520
Query: 81 LQQQQLALQLELEMQ------EKERQRI----QELQRAQEQLGKEMRMNMENLVRNEDIL 130
+ A QL E Q E+ERQR+ +E +R Q + + +R E L + E
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2580
Query: 131 HSEEATL 137
+E L
Sbjct: 2581 RQQEELL 2587
Score = 31.6 bits (70), Expect = 0.38
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 55 AKLERERELALMEQEMMERL-KAEELLL--QQQQLALQLELEMQEKERQRIQELQRAQEQ 111
AK + ERE ++Q M E + + EE + QQQ+ ++Q EL+ + + + + Q +
Sbjct: 1382 AKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE 1441
Query: 112 LGKEMRMNMENLVR 125
+ R+ +E +R
Sbjct: 1442 AAERSRLRIEEEIR 1455
Score = 31.6 bits (70), Expect = 0.38
Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ-LELEMQEKERQRIQEL 105
E RQ++ A E ER A +E+ R +AE+ +Q QLA + + +Q +E+ +
Sbjct: 1999 EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2058
Query: 106 QRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELD 162
Q+ +++L + ++ L + + + + ++R A + +VEE +
Sbjct: 2059 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2115
Score = 31.6 bits (70), Expect = 0.38
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 45 TMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE 104
T+E RQ+ ER RE + E+L+ E LLQ L+ E ++ Q +QE
Sbjct: 2433 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-----LKSEEMQTVQQEQLLQE 2487
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLD 138
Q Q+ E ++L++ E + E+A L+
Sbjct: 2488 TQALQQSFLSE----KDSLLQRERFIEQEKAKLE 2517
Score = 31.2 bits (69), Expect = 0.49
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 56 KLERERELALMEQEMMERLKAEELL----LQQQQLALQLELEMQEKERQRIQELQRAQEQ 111
K E E EL + + L+++E +Q+QLA + E +E E +R+Q+ A+E+
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE-ERVQKSLAAEEE 1999
Query: 112 LGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
++ + +E + R +A ++ + L E +++ A L +E
Sbjct: 2000 AARQRKAALEEVER-------LKAKVEEARRLRERAEQESARQLQLAQE 2041
Score = 30.0 bits (66), Expect = 1.1
Identities = 19/83 (22%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E RQ+++A+ + R+ A E+ + E+L A + + +L + E+ ++EKE + + +
Sbjct: 1812 EAKRQRQLAEEDAARQRAEAERVLAEKLAA---IGEATRLKTEAEIALKEKEAENERLRR 1868
Query: 107 RAQEQLGKEMRMNMENLVRNEDI 129
A+++ + R+ + DI
Sbjct: 1869 LAEDEAFQRRRLEEQAAQHKADI 1891
Score = 29.6 bits (65), Expect = 1.4
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQL 112
E A+ E EL E+ E LQ++ +A+ E E+ Q+ E +RA+E+
Sbjct: 1568 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1627
Query: 113 GKEM 116
+E+
Sbjct: 1628 EREL 1631
Score = 28.9 bits (63), Expect = 2.4
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 54 MAKLERERELALMEQ-EMMERLKAEELLLQQQ--------QLALQLELEMQEKERQRIQE 104
+ ++E E LA ++ E ERL E L++Q Q Q E E +E +++ +E
Sbjct: 1341 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEE 1400
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
+ R +E + + + S EA + + AE ++R
Sbjct: 1401 VVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1445
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 47.8 bits (112), Expect = 5e-06
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ RQ++ + ER+R +A ME+ + +AEE + ++Q+ QLE + +++E +E Q
Sbjct: 2537 EQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQ 2596
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEA---TLDSGK 141
R +EQL + L +E++ S+ A TL +G+
Sbjct: 2597 RLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2634
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 7/127 (5%)
Query: 16 QGLAEVARVRPVDPIEYLALWIYKYKENVTM-----EQLRQKEMAKLERERELALMEQEM 70
Q AE R R E L W K E + + E +QK +A+ E E++ E+E
Sbjct: 1619 QQQAEAERAREEAERE-LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA 1677
Query: 71 MERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
R KAEE ++Q++LA Q ELE Q + + + + A EQ +R E + +L
Sbjct: 1678 RRRGKAEEQAVRQRELAEQ-ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLL 1736
Query: 131 HSEEATL 137
E A L
Sbjct: 1737 EEELARL 1743
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-- 104
+ +RQ+E+A+ E E++ L E +RL AE Q+ + L+ E E E++RQ ++E
Sbjct: 1686 QAVRQRELAEQELEKQRQLAEGTAQQRLAAE-----QELIRLRAETEQGEQQRQLLEEEL 1740
Query: 105 --LQR---AQEQLGKEMRMNMENL-VRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
LQR A Q +E+ + + E +L S+ + ++ +E S + R
Sbjct: 1741 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1800
Query: 159 EELDE 163
EL E
Sbjct: 1801 RELAE 1805
Score = 37.0 bits (84), Expect = 0.009
Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE +E RQ+++A E ER E+ + + L AEE +Q++ AL+ ++ K +
Sbjct: 1966 KEQAELEAARQRQLAA-EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2024
Query: 101 RIQELQRAQEQLGKEMRMNME 121
+ +RA+++ +++++ E
Sbjct: 2025 ARRLRERAEQESARQLQLAQE 2045
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/93 (30%), Positives = 56/93 (60%), Gaps = 8/93 (8%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQL--ELEMQEKERQRIQE 104
E+LR++ + +R+R+ E E+ R+KAE +++Q ALQ EL +Q +E +R
Sbjct: 1501 ERLRRQVQDESQRKRQA---EVELASRVKAEAEAAREKQRALQALEELRLQAEEAER--R 1555
Query: 105 LQRAQEQLGKEMRMNMENLVRN-EDILHSEEAT 136
L++A+ + +++++ +E R+ E L S+ A+
Sbjct: 1556 LRQAEVERARQVQVALETAQRSAEAELQSKRAS 1588
Score = 35.4 bits (80), Expect = 0.026
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ----EMMERLKAE-ELLLQQQQLALQLELEMQ 95
+E + QL ++++A+ E L E+ + RLKAE ELL QQ++LA + +Q
Sbjct: 2292 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2351
Query: 96 EKERQRIQELQRAQEQLGKEMRMNME 121
E + Q Q+L A+E G + + E
Sbjct: 2352 EDKEQMAQQL--AEETQGFQRTLEAE 2375
Score = 34.7 bits (78), Expect = 0.044
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ + + A+ E+ EQE R +AE+ L+Q+Q A E+E +K ++ +
Sbjct: 2127 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQ-AADAEMEKHKKFAEQTLRQK 2185
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
EQ +R+ +E +++L E L + T A A S+VEE
Sbjct: 2186 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-------ARQRSQVEE 2232
Score = 34.3 bits (77), Expect = 0.058
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEE----LLLQQQQLALQLELEMQ------- 95
E R +E A+ E R+L L ++ +RL+AEE +QQ++ LQ L+ +
Sbjct: 2024 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2083
Query: 96 ----EKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E R+ +E + A+ Q +E + + E + S E
Sbjct: 2084 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2126
Score = 34.3 bits (77), Expect = 0.058
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 35 LWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEEL-LLQQQQLALQLELE 93
L I + + + E+LR+ +A+LERE+E E ++++ LK+EE+ +QQ+QL + +
Sbjct: 2438 LEIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQ-LKSEEMQTVQQEQLLQETQAL 2495
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
Q ++ LQR E+ ++ + +E L ++E
Sbjct: 2496 QQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2527
Score = 32.7 bits (73), Expect = 0.17
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 28/127 (22%)
Query: 39 KYKENVTMEQLRQKEMAKLEREREL---------------ALMEQEM---MERLKAEELL 80
K ++ + QL+ +EM +++E+ L +L+++E E+ K E+L
Sbjct: 2465 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2524
Query: 81 LQQQQLALQLELEMQ------EKERQRI----QELQRAQEQLGKEMRMNMENLVRNEDIL 130
+ A QL E Q E+ERQR+ +E +R Q + + +R E L + E
Sbjct: 2525 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2584
Query: 131 HSEEATL 137
+E L
Sbjct: 2585 RQQEELL 2591
Score = 31.6 bits (70), Expect = 0.38
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 55 AKLERERELALMEQEMMERL-KAEELLL--QQQQLALQLELEMQEKERQRIQELQRAQEQ 111
AK + ERE ++Q M E + + EE + QQQ+ ++Q EL+ + + + + Q +
Sbjct: 1386 AKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE 1445
Query: 112 LGKEMRMNMENLVR 125
+ R+ +E +R
Sbjct: 1446 AAERSRLRIEEEIR 1459
Score = 31.6 bits (70), Expect = 0.38
Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ-LELEMQEKERQRIQEL 105
E RQ++ A E ER A +E+ R +AE+ +Q QLA + + +Q +E+ +
Sbjct: 2003 EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2062
Query: 106 QRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELD 162
Q+ +++L + ++ L + + + + ++R A + +VEE +
Sbjct: 2063 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2119
Score = 31.6 bits (70), Expect = 0.38
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 45 TMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE 104
T+E RQ+ ER RE + E+L+ E LLQ L+ E ++ Q +QE
Sbjct: 2437 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-----LKSEEMQTVQQEQLLQE 2491
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLD 138
Q Q+ E ++L++ E + E+A L+
Sbjct: 2492 TQALQQSFLSE----KDSLLQRERFIEQEKAKLE 2521
Score = 31.2 bits (69), Expect = 0.49
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 56 KLERERELALMEQEMMERLKAEELL----LQQQQLALQLELEMQEKERQRIQELQRAQEQ 111
K E E EL + + L+++E +Q+QLA + E +E E +R+Q+ A+E+
Sbjct: 1945 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE-ERVQKSLAAEEE 2003
Query: 112 LGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
++ + +E + R +A ++ + L E +++ A L +E
Sbjct: 2004 AARQRKAALEEVER-------LKAKVEEARRLRERAEQESARQLQLAQE 2045
Score = 30.0 bits (66), Expect = 1.1
Identities = 19/83 (22%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E RQ+++A+ + R+ A E+ + E+L A + + +L + E+ ++EKE + + +
Sbjct: 1816 EAKRQRQLAEEDAARQRAEAERVLAEKLAA---IGEATRLKTEAEIALKEKEAENERLRR 1872
Query: 107 RAQEQLGKEMRMNMENLVRNEDI 129
A+++ + R+ + DI
Sbjct: 1873 LAEDEAFQRRRLEEQAAQHKADI 1895
Score = 29.6 bits (65), Expect = 1.4
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQL 112
E A+ E EL E+ E LQ++ +A+ E E+ Q+ E +RA+E+
Sbjct: 1572 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1631
Query: 113 GKEM 116
+E+
Sbjct: 1632 EREL 1635
Score = 28.9 bits (63), Expect = 2.4
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 54 MAKLERERELALMEQ-EMMERLKAEELLLQQQ--------QLALQLELEMQEKERQRIQE 104
+ ++E E LA ++ E ERL E L++Q Q Q E E +E +++ +E
Sbjct: 1345 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEE 1404
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
+ R +E + + + S EA + + AE ++R
Sbjct: 1405 VVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1449
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 47.8 bits (112), Expect = 5e-06
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ RQ++ + ER+R +A ME+ + +AEE + ++Q+ QLE + +++E +E Q
Sbjct: 2533 EQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQ 2592
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEA---TLDSGK 141
R +EQL + L +E++ S+ A TL +G+
Sbjct: 2593 RLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2630
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 7/127 (5%)
Query: 16 QGLAEVARVRPVDPIEYLALWIYKYKENVTM-----EQLRQKEMAKLERERELALMEQEM 70
Q AE R R E L W K E + + E +QK +A+ E E++ E+E
Sbjct: 1615 QQQAEAERAREEAERE-LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA 1673
Query: 71 MERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
R KAEE ++Q++LA Q ELE Q + + + + A EQ +R E + +L
Sbjct: 1674 RRRGKAEEQAVRQRELAEQ-ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLL 1732
Query: 131 HSEEATL 137
E A L
Sbjct: 1733 EEELARL 1739
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-- 104
+ +RQ+E+A+ E E++ L E +RL AE Q+ + L+ E E E++RQ ++E
Sbjct: 1682 QAVRQRELAEQELEKQRQLAEGTAQQRLAAE-----QELIRLRAETEQGEQQRQLLEEEL 1736
Query: 105 --LQR---AQEQLGKEMRMNMENL-VRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
LQR A Q +E+ + + E +L S+ + ++ +E S + R
Sbjct: 1737 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1796
Query: 159 EELDE 163
EL E
Sbjct: 1797 RELAE 1801
Score = 37.0 bits (84), Expect = 0.009
Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE +E RQ+++A E ER E+ + + L AEE +Q++ AL+ ++ K +
Sbjct: 1962 KEQAELEAARQRQLAA-EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2020
Query: 101 RIQELQRAQEQLGKEMRMNME 121
+ +RA+++ +++++ E
Sbjct: 2021 ARRLRERAEQESARQLQLAQE 2041
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/93 (30%), Positives = 56/93 (60%), Gaps = 8/93 (8%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQL--ELEMQEKERQRIQE 104
E+LR++ + +R+R+ E E+ R+KAE +++Q ALQ EL +Q +E +R
Sbjct: 1497 ERLRRQVQDESQRKRQA---EVELASRVKAEAEAAREKQRALQALEELRLQAEEAER--R 1551
Query: 105 LQRAQEQLGKEMRMNMENLVRN-EDILHSEEAT 136
L++A+ + +++++ +E R+ E L S+ A+
Sbjct: 1552 LRQAEVERARQVQVALETAQRSAEAELQSKRAS 1584
Score = 35.4 bits (80), Expect = 0.026
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ----EMMERLKAE-ELLLQQQQLALQLELEMQ 95
+E + QL ++++A+ E L E+ + RLKAE ELL QQ++LA + +Q
Sbjct: 2288 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2347
Query: 96 EKERQRIQELQRAQEQLGKEMRMNME 121
E + Q Q+L A+E G + + E
Sbjct: 2348 EDKEQMAQQL--AEETQGFQRTLEAE 2371
Score = 34.7 bits (78), Expect = 0.044
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ + + A+ E+ EQE R +AE+ L+Q+Q A E+E +K ++ +
Sbjct: 2123 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQ-AADAEMEKHKKFAEQTLRQK 2181
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
EQ +R+ +E +++L E L + T A A S+VEE
Sbjct: 2182 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-------ARQRSQVEE 2228
Score = 34.3 bits (77), Expect = 0.058
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEE----LLLQQQQLALQLELEMQ------- 95
E R +E A+ E R+L L ++ +RL+AEE +QQ++ LQ L+ +
Sbjct: 2020 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2079
Query: 96 ----EKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E R+ +E + A+ Q +E + + E + S E
Sbjct: 2080 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2122
Score = 34.3 bits (77), Expect = 0.058
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 35 LWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEEL-LLQQQQLALQLELE 93
L I + + + E+LR+ +A+LERE+E E ++++ LK+EE+ +QQ+QL + +
Sbjct: 2434 LEIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQ-LKSEEMQTVQQEQLLQETQAL 2491
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
Q ++ LQR E+ ++ + +E L ++E
Sbjct: 2492 QQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2523
Score = 32.7 bits (73), Expect = 0.17
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 28/127 (22%)
Query: 39 KYKENVTMEQLRQKEMAKLEREREL---------------ALMEQEM---MERLKAEELL 80
K ++ + QL+ +EM +++E+ L +L+++E E+ K E+L
Sbjct: 2461 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2520
Query: 81 LQQQQLALQLELEMQ------EKERQRI----QELQRAQEQLGKEMRMNMENLVRNEDIL 130
+ A QL E Q E+ERQR+ +E +R Q + + +R E L + E
Sbjct: 2521 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2580
Query: 131 HSEEATL 137
+E L
Sbjct: 2581 RQQEELL 2587
Score = 31.6 bits (70), Expect = 0.38
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 55 AKLERERELALMEQEMMERL-KAEELLL--QQQQLALQLELEMQEKERQRIQELQRAQEQ 111
AK + ERE ++Q M E + + EE + QQQ+ ++Q EL+ + + + + Q +
Sbjct: 1382 AKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE 1441
Query: 112 LGKEMRMNMENLVR 125
+ R+ +E +R
Sbjct: 1442 AAERSRLRIEEEIR 1455
Score = 31.6 bits (70), Expect = 0.38
Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ-LELEMQEKERQRIQEL 105
E RQ++ A E ER A +E+ R +AE+ +Q QLA + + +Q +E+ +
Sbjct: 1999 EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2058
Query: 106 QRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELD 162
Q+ +++L + ++ L + + + + ++R A + +VEE +
Sbjct: 2059 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2115
Score = 31.6 bits (70), Expect = 0.38
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 45 TMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE 104
T+E RQ+ ER RE + E+L+ E LLQ L+ E ++ Q +QE
Sbjct: 2433 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-----LKSEEMQTVQQEQLLQE 2487
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLD 138
Q Q+ E ++L++ E + E+A L+
Sbjct: 2488 TQALQQSFLSE----KDSLLQRERFIEQEKAKLE 2517
Score = 31.2 bits (69), Expect = 0.49
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 56 KLERERELALMEQEMMERLKAEELL----LQQQQLALQLELEMQEKERQRIQELQRAQEQ 111
K E E EL + + L+++E +Q+QLA + E +E E +R+Q+ A+E+
Sbjct: 1941 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE-ERVQKSLAAEEE 1999
Query: 112 LGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
++ + +E + R +A ++ + L E +++ A L +E
Sbjct: 2000 AARQRKAALEEVER-------LKAKVEEARRLRERAEQESARQLQLAQE 2041
Score = 30.0 bits (66), Expect = 1.1
Identities = 19/83 (22%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E RQ+++A+ + R+ A E+ + E+L A + + +L + E+ ++EKE + + +
Sbjct: 1812 EAKRQRQLAEEDAARQRAEAERVLAEKLAA---IGEATRLKTEAEIALKEKEAENERLRR 1868
Query: 107 RAQEQLGKEMRMNMENLVRNEDI 129
A+++ + R+ + DI
Sbjct: 1869 LAEDEAFQRRRLEEQAAQHKADI 1891
Score = 29.6 bits (65), Expect = 1.4
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQL 112
E A+ E EL E+ E LQ++ +A+ E E+ Q+ E +RA+E+
Sbjct: 1568 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1627
Query: 113 GKEM 116
+E+
Sbjct: 1628 EREL 1631
Score = 28.9 bits (63), Expect = 2.4
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 54 MAKLERERELALMEQ-EMMERLKAEELLLQQQ--------QLALQLELEMQEKERQRIQE 104
+ ++E E LA ++ E ERL E L++Q Q Q E E +E +++ +E
Sbjct: 1341 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEE 1400
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
+ R +E + + + S EA + + AE ++R
Sbjct: 1401 VVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1445
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 47.8 bits (112), Expect = 5e-06
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ RQ++ + ER+R +A ME+ + +AEE + ++Q+ QLE + +++E +E Q
Sbjct: 2501 EQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQ 2560
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEA---TLDSGK 141
R +EQL + L +E++ S+ A TL +G+
Sbjct: 2561 RLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2598
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 7/127 (5%)
Query: 16 QGLAEVARVRPVDPIEYLALWIYKYKENVTM-----EQLRQKEMAKLERERELALMEQEM 70
Q AE R R E L W K E + + E +QK +A+ E E++ E+E
Sbjct: 1583 QQQAEAERAREEAERE-LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA 1641
Query: 71 MERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
R KAEE ++Q++LA Q ELE Q + + + + A EQ +R E + +L
Sbjct: 1642 RRRGKAEEQAVRQRELAEQ-ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLL 1700
Query: 131 HSEEATL 137
E A L
Sbjct: 1701 EEELARL 1707
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-- 104
+ +RQ+E+A+ E E++ L E +RL AE Q+ + L+ E E E++RQ ++E
Sbjct: 1650 QAVRQRELAEQELEKQRQLAEGTAQQRLAAE-----QELIRLRAETEQGEQQRQLLEEEL 1704
Query: 105 --LQR---AQEQLGKEMRMNMENL-VRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
LQR A Q +E+ + + E +L S+ + ++ +E S + R
Sbjct: 1705 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1764
Query: 159 EELDE 163
EL E
Sbjct: 1765 RELAE 1769
Score = 37.0 bits (84), Expect = 0.009
Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE +E RQ+++A E ER E+ + + L AEE +Q++ AL+ ++ K +
Sbjct: 1930 KEQAELEAARQRQLAA-EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 1988
Query: 101 RIQELQRAQEQLGKEMRMNME 121
+ +RA+++ +++++ E
Sbjct: 1989 ARRLRERAEQESARQLQLAQE 2009
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/93 (30%), Positives = 56/93 (60%), Gaps = 8/93 (8%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQL--ELEMQEKERQRIQE 104
E+LR++ + +R+R+ E E+ R+KAE +++Q ALQ EL +Q +E +R
Sbjct: 1465 ERLRRQVQDESQRKRQA---EVELASRVKAEAEAAREKQRALQALEELRLQAEEAER--R 1519
Query: 105 LQRAQEQLGKEMRMNMENLVRN-EDILHSEEAT 136
L++A+ + +++++ +E R+ E L S+ A+
Sbjct: 1520 LRQAEVERARQVQVALETAQRSAEAELQSKRAS 1552
Score = 35.4 bits (80), Expect = 0.026
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ----EMMERLKAE-ELLLQQQQLALQLELEMQ 95
+E + QL ++++A+ E L E+ + RLKAE ELL QQ++LA + +Q
Sbjct: 2256 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2315
Query: 96 EKERQRIQELQRAQEQLGKEMRMNME 121
E + Q Q+L A+E G + + E
Sbjct: 2316 EDKEQMAQQL--AEETQGFQRTLEAE 2339
Score = 34.7 bits (78), Expect = 0.044
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ + + A+ E+ EQE R +AE+ L+Q+Q A E+E +K ++ +
Sbjct: 2091 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQ-AADAEMEKHKKFAEQTLRQK 2149
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
EQ +R+ +E +++L E L + T A A S+VEE
Sbjct: 2150 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-------ARQRSQVEE 2196
Score = 34.3 bits (77), Expect = 0.058
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEE----LLLQQQQLALQLELEMQ------- 95
E R +E A+ E R+L L ++ +RL+AEE +QQ++ LQ L+ +
Sbjct: 1988 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2047
Query: 96 ----EKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E R+ +E + A+ Q +E + + E + S E
Sbjct: 2048 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2090
Score = 34.3 bits (77), Expect = 0.058
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 35 LWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEEL-LLQQQQLALQLELE 93
L I + + + E+LR+ +A+LERE+E E ++++ LK+EE+ +QQ+QL + +
Sbjct: 2402 LEIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQ-LKSEEMQTVQQEQLLQETQAL 2459
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
Q ++ LQR E+ ++ + +E L ++E
Sbjct: 2460 QQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2491
Score = 32.7 bits (73), Expect = 0.17
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 28/127 (22%)
Query: 39 KYKENVTMEQLRQKEMAKLEREREL---------------ALMEQEM---MERLKAEELL 80
K ++ + QL+ +EM +++E+ L +L+++E E+ K E+L
Sbjct: 2429 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2488
Query: 81 LQQQQLALQLELEMQ------EKERQRI----QELQRAQEQLGKEMRMNMENLVRNEDIL 130
+ A QL E Q E+ERQR+ +E +R Q + + +R E L + E
Sbjct: 2489 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2548
Query: 131 HSEEATL 137
+E L
Sbjct: 2549 RQQEELL 2555
Score = 31.6 bits (70), Expect = 0.38
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 55 AKLERERELALMEQEMMERL-KAEELLL--QQQQLALQLELEMQEKERQRIQELQRAQEQ 111
AK + ERE ++Q M E + + EE + QQQ+ ++Q EL+ + + + + Q +
Sbjct: 1350 AKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE 1409
Query: 112 LGKEMRMNMENLVR 125
+ R+ +E +R
Sbjct: 1410 AAERSRLRIEEEIR 1423
Score = 31.6 bits (70), Expect = 0.38
Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ-LELEMQEKERQRIQEL 105
E RQ++ A E ER A +E+ R +AE+ +Q QLA + + +Q +E+ +
Sbjct: 1967 EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2026
Query: 106 QRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELD 162
Q+ +++L + ++ L + + + + ++R A + +VEE +
Sbjct: 2027 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2083
Score = 31.6 bits (70), Expect = 0.38
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 45 TMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE 104
T+E RQ+ ER RE + E+L+ E LLQ L+ E ++ Q +QE
Sbjct: 2401 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-----LKSEEMQTVQQEQLLQE 2455
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLD 138
Q Q+ E ++L++ E + E+A L+
Sbjct: 2456 TQALQQSFLSE----KDSLLQRERFIEQEKAKLE 2485
Score = 31.2 bits (69), Expect = 0.49
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 56 KLERERELALMEQEMMERLKAEELL----LQQQQLALQLELEMQEKERQRIQELQRAQEQ 111
K E E EL + + L+++E +Q+QLA + E +E E +R+Q+ A+E+
Sbjct: 1909 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE-ERVQKSLAAEEE 1967
Query: 112 LGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
++ + +E + R +A ++ + L E +++ A L +E
Sbjct: 1968 AARQRKAALEEVER-------LKAKVEEARRLRERAEQESARQLQLAQE 2009
Score = 30.0 bits (66), Expect = 1.1
Identities = 19/83 (22%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E RQ+++A+ + R+ A E+ + E+L A + + +L + E+ ++EKE + + +
Sbjct: 1780 EAKRQRQLAEEDAARQRAEAERVLAEKLAA---IGEATRLKTEAEIALKEKEAENERLRR 1836
Query: 107 RAQEQLGKEMRMNMENLVRNEDI 129
A+++ + R+ + DI
Sbjct: 1837 LAEDEAFQRRRLEEQAAQHKADI 1859
Score = 29.6 bits (65), Expect = 1.4
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQL 112
E A+ E EL E+ E LQ++ +A+ E E+ Q+ E +RA+E+
Sbjct: 1536 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1595
Query: 113 GKEM 116
+E+
Sbjct: 1596 EREL 1599
Score = 28.9 bits (63), Expect = 2.4
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 54 MAKLERERELALMEQ-EMMERLKAEELLLQQQ--------QLALQLELEMQEKERQRIQE 104
+ ++E E LA ++ E ERL E L++Q Q Q E E +E +++ +E
Sbjct: 1309 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEE 1368
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
+ R +E + + + S EA + + AE ++R
Sbjct: 1369 VVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1413
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 47.8 bits (112), Expect = 5e-06
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ RQ++ + ER+R +A ME+ + +AEE + ++Q+ QLE + +++E +E Q
Sbjct: 2670 EQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQ 2729
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEA---TLDSGK 141
R +EQL + L +E++ S+ A TL +G+
Sbjct: 2730 RLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2767
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 7/127 (5%)
Query: 16 QGLAEVARVRPVDPIEYLALWIYKYKENVTM-----EQLRQKEMAKLERERELALMEQEM 70
Q AE R R E L W K E + + E +QK +A+ E E++ E+E
Sbjct: 1752 QQQAEAERAREEAERE-LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA 1810
Query: 71 MERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
R KAEE ++Q++LA Q ELE Q + + + + A EQ +R E + +L
Sbjct: 1811 RRRGKAEEQAVRQRELAEQ-ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLL 1869
Query: 131 HSEEATL 137
E A L
Sbjct: 1870 EEELARL 1876
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-- 104
+ +RQ+E+A+ E E++ L E +RL AE Q+ + L+ E E E++RQ ++E
Sbjct: 1819 QAVRQRELAEQELEKQRQLAEGTAQQRLAAE-----QELIRLRAETEQGEQQRQLLEEEL 1873
Query: 105 --LQR---AQEQLGKEMRMNMENL-VRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
LQR A Q +E+ + + E +L S+ + ++ +E S + R
Sbjct: 1874 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1933
Query: 159 EELDE 163
EL E
Sbjct: 1934 RELAE 1938
Score = 37.0 bits (84), Expect = 0.009
Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE +E RQ+++A E ER E+ + + L AEE +Q++ AL+ ++ K +
Sbjct: 2099 KEQAELEAARQRQLAA-EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2157
Query: 101 RIQELQRAQEQLGKEMRMNME 121
+ +RA+++ +++++ E
Sbjct: 2158 ARRLRERAEQESARQLQLAQE 2178
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/93 (30%), Positives = 56/93 (60%), Gaps = 8/93 (8%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQL--ELEMQEKERQRIQE 104
E+LR++ + +R+R+ E E+ R+KAE +++Q ALQ EL +Q +E +R
Sbjct: 1634 ERLRRQVQDESQRKRQA---EVELASRVKAEAEAAREKQRALQALEELRLQAEEAER--R 1688
Query: 105 LQRAQEQLGKEMRMNMENLVRN-EDILHSEEAT 136
L++A+ + +++++ +E R+ E L S+ A+
Sbjct: 1689 LRQAEVERARQVQVALETAQRSAEAELQSKRAS 1721
Score = 35.4 bits (80), Expect = 0.026
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ----EMMERLKAE-ELLLQQQQLALQLELEMQ 95
+E + QL ++++A+ E L E+ + RLKAE ELL QQ++LA + +Q
Sbjct: 2425 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2484
Query: 96 EKERQRIQELQRAQEQLGKEMRMNME 121
E + Q Q+L A+E G + + E
Sbjct: 2485 EDKEQMAQQL--AEETQGFQRTLEAE 2508
Score = 34.7 bits (78), Expect = 0.044
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ + + A+ E+ EQE R +AE+ L+Q+Q A E+E +K ++ +
Sbjct: 2260 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQ-AADAEMEKHKKFAEQTLRQK 2318
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
EQ +R+ +E +++L E L + T A A S+VEE
Sbjct: 2319 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-------ARQRSQVEE 2365
Score = 34.3 bits (77), Expect = 0.058
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEE----LLLQQQQLALQLELEMQ------- 95
E R +E A+ E R+L L ++ +RL+AEE +QQ++ LQ L+ +
Sbjct: 2157 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2216
Query: 96 ----EKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E R+ +E + A+ Q +E + + E + S E
Sbjct: 2217 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2259
Score = 34.3 bits (77), Expect = 0.058
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 35 LWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEEL-LLQQQQLALQLELE 93
L I + + + E+LR+ +A+LERE+E E ++++ LK+EE+ +QQ+QL + +
Sbjct: 2571 LEIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQ-LKSEEMQTVQQEQLLQETQAL 2628
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
Q ++ LQR E+ ++ + +E L ++E
Sbjct: 2629 QQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2660
Score = 32.7 bits (73), Expect = 0.17
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 28/127 (22%)
Query: 39 KYKENVTMEQLRQKEMAKLEREREL---------------ALMEQEM---MERLKAEELL 80
K ++ + QL+ +EM +++E+ L +L+++E E+ K E+L
Sbjct: 2598 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2657
Query: 81 LQQQQLALQLELEMQ------EKERQRI----QELQRAQEQLGKEMRMNMENLVRNEDIL 130
+ A QL E Q E+ERQR+ +E +R Q + + +R E L + E
Sbjct: 2658 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2717
Query: 131 HSEEATL 137
+E L
Sbjct: 2718 RQQEELL 2724
Score = 31.6 bits (70), Expect = 0.38
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 55 AKLERERELALMEQEMMERL-KAEELLL--QQQQLALQLELEMQEKERQRIQELQRAQEQ 111
AK + ERE ++Q M E + + EE + QQQ+ ++Q EL+ + + + + Q +
Sbjct: 1519 AKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE 1578
Query: 112 LGKEMRMNMENLVR 125
+ R+ +E +R
Sbjct: 1579 AAERSRLRIEEEIR 1592
Score = 31.6 bits (70), Expect = 0.38
Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ-LELEMQEKERQRIQEL 105
E RQ++ A E ER A +E+ R +AE+ +Q QLA + + +Q +E+ +
Sbjct: 2136 EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2195
Query: 106 QRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELD 162
Q+ +++L + ++ L + + + + ++R A + +VEE +
Sbjct: 2196 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2252
Score = 31.6 bits (70), Expect = 0.38
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 45 TMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE 104
T+E RQ+ ER RE + E+L+ E LLQ L+ E ++ Q +QE
Sbjct: 2570 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-----LKSEEMQTVQQEQLLQE 2624
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLD 138
Q Q+ E ++L++ E + E+A L+
Sbjct: 2625 TQALQQSFLSE----KDSLLQRERFIEQEKAKLE 2654
Score = 31.2 bits (69), Expect = 0.49
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 56 KLERERELALMEQEMMERLKAEELL----LQQQQLALQLELEMQEKERQRIQELQRAQEQ 111
K E E EL + + L+++E +Q+QLA + E +E E +R+Q+ A+E+
Sbjct: 2078 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE-ERVQKSLAAEEE 2136
Query: 112 LGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
++ + +E + R +A ++ + L E +++ A L +E
Sbjct: 2137 AARQRKAALEEVER-------LKAKVEEARRLRERAEQESARQLQLAQE 2178
Score = 30.0 bits (66), Expect = 1.1
Identities = 19/83 (22%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E RQ+++A+ + R+ A E+ + E+L A + + +L + E+ ++EKE + + +
Sbjct: 1949 EAKRQRQLAEEDAARQRAEAERVLAEKLAA---IGEATRLKTEAEIALKEKEAENERLRR 2005
Query: 107 RAQEQLGKEMRMNMENLVRNEDI 129
A+++ + R+ + DI
Sbjct: 2006 LAEDEAFQRRRLEEQAAQHKADI 2028
Score = 29.6 bits (65), Expect = 1.4
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQL 112
E A+ E EL E+ E LQ++ +A+ E E+ Q+ E +RA+E+
Sbjct: 1705 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1764
Query: 113 GKEM 116
+E+
Sbjct: 1765 EREL 1768
Score = 28.9 bits (63), Expect = 2.4
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 54 MAKLERERELALMEQ-EMMERLKAEELLLQQQ--------QLALQLELEMQEKERQRIQE 104
+ ++E E LA ++ E ERL E L++Q Q Q E E +E +++ +E
Sbjct: 1478 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEE 1537
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
+ R +E + + + S EA + + AE ++R
Sbjct: 1538 VVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1582
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 47.8 bits (112), Expect = 5e-06
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ RQ++ + ER+R +A ME+ + +AEE + ++Q+ QLE + +++E +E Q
Sbjct: 2511 EQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQ 2570
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEA---TLDSGK 141
R +EQL + L +E++ S+ A TL +G+
Sbjct: 2571 RLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2608
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 7/127 (5%)
Query: 16 QGLAEVARVRPVDPIEYLALWIYKYKENVTM-----EQLRQKEMAKLERERELALMEQEM 70
Q AE R R E L W K E + + E +QK +A+ E E++ E+E
Sbjct: 1593 QQQAEAERAREEAERE-LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA 1651
Query: 71 MERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
R KAEE ++Q++LA Q ELE Q + + + + A EQ +R E + +L
Sbjct: 1652 RRRGKAEEQAVRQRELAEQ-ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLL 1710
Query: 131 HSEEATL 137
E A L
Sbjct: 1711 EEELARL 1717
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-- 104
+ +RQ+E+A+ E E++ L E +RL AE Q+ + L+ E E E++RQ ++E
Sbjct: 1660 QAVRQRELAEQELEKQRQLAEGTAQQRLAAE-----QELIRLRAETEQGEQQRQLLEEEL 1714
Query: 105 --LQR---AQEQLGKEMRMNMENL-VRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
LQR A Q +E+ + + E +L S+ + ++ +E S + R
Sbjct: 1715 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1774
Query: 159 EELDE 163
EL E
Sbjct: 1775 RELAE 1779
Score = 37.0 bits (84), Expect = 0.009
Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE +E RQ+++A E ER E+ + + L AEE +Q++ AL+ ++ K +
Sbjct: 1940 KEQAELEAARQRQLAA-EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 1998
Query: 101 RIQELQRAQEQLGKEMRMNME 121
+ +RA+++ +++++ E
Sbjct: 1999 ARRLRERAEQESARQLQLAQE 2019
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/93 (30%), Positives = 56/93 (60%), Gaps = 8/93 (8%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQL--ELEMQEKERQRIQE 104
E+LR++ + +R+R+ E E+ R+KAE +++Q ALQ EL +Q +E +R
Sbjct: 1475 ERLRRQVQDESQRKRQA---EVELASRVKAEAEAAREKQRALQALEELRLQAEEAER--R 1529
Query: 105 LQRAQEQLGKEMRMNMENLVRN-EDILHSEEAT 136
L++A+ + +++++ +E R+ E L S+ A+
Sbjct: 1530 LRQAEVERARQVQVALETAQRSAEAELQSKRAS 1562
Score = 35.4 bits (80), Expect = 0.026
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ----EMMERLKAE-ELLLQQQQLALQLELEMQ 95
+E + QL ++++A+ E L E+ + RLKAE ELL QQ++LA + +Q
Sbjct: 2266 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2325
Query: 96 EKERQRIQELQRAQEQLGKEMRMNME 121
E + Q Q+L A+E G + + E
Sbjct: 2326 EDKEQMAQQL--AEETQGFQRTLEAE 2349
Score = 34.7 bits (78), Expect = 0.044
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ + + A+ E+ EQE R +AE+ L+Q+Q A E+E +K ++ +
Sbjct: 2101 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQ-AADAEMEKHKKFAEQTLRQK 2159
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
EQ +R+ +E +++L E L + T A A S+VEE
Sbjct: 2160 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-------ARQRSQVEE 2206
Score = 34.3 bits (77), Expect = 0.058
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEE----LLLQQQQLALQLELEMQ------- 95
E R +E A+ E R+L L ++ +RL+AEE +QQ++ LQ L+ +
Sbjct: 1998 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2057
Query: 96 ----EKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E R+ +E + A+ Q +E + + E + S E
Sbjct: 2058 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2100
Score = 34.3 bits (77), Expect = 0.058
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 35 LWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEEL-LLQQQQLALQLELE 93
L I + + + E+LR+ +A+LERE+E E ++++ LK+EE+ +QQ+QL + +
Sbjct: 2412 LEIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQ-LKSEEMQTVQQEQLLQETQAL 2469
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
Q ++ LQR E+ ++ + +E L ++E
Sbjct: 2470 QQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2501
Score = 32.7 bits (73), Expect = 0.17
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 28/127 (22%)
Query: 39 KYKENVTMEQLRQKEMAKLEREREL---------------ALMEQEM---MERLKAEELL 80
K ++ + QL+ +EM +++E+ L +L+++E E+ K E+L
Sbjct: 2439 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2498
Query: 81 LQQQQLALQLELEMQ------EKERQRI----QELQRAQEQLGKEMRMNMENLVRNEDIL 130
+ A QL E Q E+ERQR+ +E +R Q + + +R E L + E
Sbjct: 2499 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2558
Query: 131 HSEEATL 137
+E L
Sbjct: 2559 RQQEELL 2565
Score = 31.6 bits (70), Expect = 0.38
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 55 AKLERERELALMEQEMMERL-KAEELLL--QQQQLALQLELEMQEKERQRIQELQRAQEQ 111
AK + ERE ++Q M E + + EE + QQQ+ ++Q EL+ + + + + Q +
Sbjct: 1360 AKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE 1419
Query: 112 LGKEMRMNMENLVR 125
+ R+ +E +R
Sbjct: 1420 AAERSRLRIEEEIR 1433
Score = 31.6 bits (70), Expect = 0.38
Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ-LELEMQEKERQRIQEL 105
E RQ++ A E ER A +E+ R +AE+ +Q QLA + + +Q +E+ +
Sbjct: 1977 EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2036
Query: 106 QRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELD 162
Q+ +++L + ++ L + + + + ++R A + +VEE +
Sbjct: 2037 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2093
Score = 31.6 bits (70), Expect = 0.38
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 45 TMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE 104
T+E RQ+ ER RE + E+L+ E LLQ L+ E ++ Q +QE
Sbjct: 2411 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-----LKSEEMQTVQQEQLLQE 2465
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLD 138
Q Q+ E ++L++ E + E+A L+
Sbjct: 2466 TQALQQSFLSE----KDSLLQRERFIEQEKAKLE 2495
Score = 31.2 bits (69), Expect = 0.49
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 56 KLERERELALMEQEMMERLKAEELL----LQQQQLALQLELEMQEKERQRIQELQRAQEQ 111
K E E EL + + L+++E +Q+QLA + E +E E +R+Q+ A+E+
Sbjct: 1919 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE-ERVQKSLAAEEE 1977
Query: 112 LGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
++ + +E + R +A ++ + L E +++ A L +E
Sbjct: 1978 AARQRKAALEEVER-------LKAKVEEARRLRERAEQESARQLQLAQE 2019
Score = 30.0 bits (66), Expect = 1.1
Identities = 19/83 (22%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E RQ+++A+ + R+ A E+ + E+L A + + +L + E+ ++EKE + + +
Sbjct: 1790 EAKRQRQLAEEDAARQRAEAERVLAEKLAA---IGEATRLKTEAEIALKEKEAENERLRR 1846
Query: 107 RAQEQLGKEMRMNMENLVRNEDI 129
A+++ + R+ + DI
Sbjct: 1847 LAEDEAFQRRRLEEQAAQHKADI 1869
Score = 29.6 bits (65), Expect = 1.4
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQL 112
E A+ E EL E+ E LQ++ +A+ E E+ Q+ E +RA+E+
Sbjct: 1546 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1605
Query: 113 GKEM 116
+E+
Sbjct: 1606 EREL 1609
Score = 28.9 bits (63), Expect = 2.4
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 54 MAKLERERELALMEQ-EMMERLKAEELLLQQQ--------QLALQLELEMQEKERQRIQE 104
+ ++E E LA ++ E ERL E L++Q Q Q E E +E +++ +E
Sbjct: 1319 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEE 1378
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
+ R +E + + + S EA + + AE ++R
Sbjct: 1379 VVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1423
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 47.8 bits (112), Expect = 5e-06
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ RQ++ + ER+R +A ME+ + +AEE + ++Q+ QLE + +++E +E Q
Sbjct: 2519 EQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQ 2578
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEA---TLDSGK 141
R +EQL + L +E++ S+ A TL +G+
Sbjct: 2579 RLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2616
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 7/127 (5%)
Query: 16 QGLAEVARVRPVDPIEYLALWIYKYKENVTM-----EQLRQKEMAKLERERELALMEQEM 70
Q AE R R E L W K E + + E +QK +A+ E E++ E+E
Sbjct: 1601 QQQAEAERAREEAERE-LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA 1659
Query: 71 MERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
R KAEE ++Q++LA Q ELE Q + + + + A EQ +R E + +L
Sbjct: 1660 RRRGKAEEQAVRQRELAEQ-ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLL 1718
Query: 131 HSEEATL 137
E A L
Sbjct: 1719 EEELARL 1725
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-- 104
+ +RQ+E+A+ E E++ L E +RL AE Q+ + L+ E E E++RQ ++E
Sbjct: 1668 QAVRQRELAEQELEKQRQLAEGTAQQRLAAE-----QELIRLRAETEQGEQQRQLLEEEL 1722
Query: 105 --LQR---AQEQLGKEMRMNMENL-VRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
LQR A Q +E+ + + E +L S+ + ++ +E S + R
Sbjct: 1723 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1782
Query: 159 EELDE 163
EL E
Sbjct: 1783 RELAE 1787
Score = 37.0 bits (84), Expect = 0.009
Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE +E RQ+++A E ER E+ + + L AEE +Q++ AL+ ++ K +
Sbjct: 1948 KEQAELEAARQRQLAA-EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2006
Query: 101 RIQELQRAQEQLGKEMRMNME 121
+ +RA+++ +++++ E
Sbjct: 2007 ARRLRERAEQESARQLQLAQE 2027
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/93 (30%), Positives = 56/93 (60%), Gaps = 8/93 (8%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQL--ELEMQEKERQRIQE 104
E+LR++ + +R+R+ E E+ R+KAE +++Q ALQ EL +Q +E +R
Sbjct: 1483 ERLRRQVQDESQRKRQA---EVELASRVKAEAEAAREKQRALQALEELRLQAEEAER--R 1537
Query: 105 LQRAQEQLGKEMRMNMENLVRN-EDILHSEEAT 136
L++A+ + +++++ +E R+ E L S+ A+
Sbjct: 1538 LRQAEVERARQVQVALETAQRSAEAELQSKRAS 1570
Score = 35.4 bits (80), Expect = 0.026
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ----EMMERLKAE-ELLLQQQQLALQLELEMQ 95
+E + QL ++++A+ E L E+ + RLKAE ELL QQ++LA + +Q
Sbjct: 2274 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2333
Query: 96 EKERQRIQELQRAQEQLGKEMRMNME 121
E + Q Q+L A+E G + + E
Sbjct: 2334 EDKEQMAQQL--AEETQGFQRTLEAE 2357
Score = 34.7 bits (78), Expect = 0.044
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ + + A+ E+ EQE R +AE+ L+Q+Q A E+E +K ++ +
Sbjct: 2109 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQ-AADAEMEKHKKFAEQTLRQK 2167
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
EQ +R+ +E +++L E L + T A A S+VEE
Sbjct: 2168 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-------ARQRSQVEE 2214
Score = 34.3 bits (77), Expect = 0.058
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEE----LLLQQQQLALQLELEMQ------- 95
E R +E A+ E R+L L ++ +RL+AEE +QQ++ LQ L+ +
Sbjct: 2006 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2065
Query: 96 ----EKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E R+ +E + A+ Q +E + + E + S E
Sbjct: 2066 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2108
Score = 34.3 bits (77), Expect = 0.058
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 35 LWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEEL-LLQQQQLALQLELE 93
L I + + + E+LR+ +A+LERE+E E ++++ LK+EE+ +QQ+QL + +
Sbjct: 2420 LEIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQ-LKSEEMQTVQQEQLLQETQAL 2477
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
Q ++ LQR E+ ++ + +E L ++E
Sbjct: 2478 QQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2509
Score = 32.7 bits (73), Expect = 0.17
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 28/127 (22%)
Query: 39 KYKENVTMEQLRQKEMAKLEREREL---------------ALMEQEM---MERLKAEELL 80
K ++ + QL+ +EM +++E+ L +L+++E E+ K E+L
Sbjct: 2447 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2506
Query: 81 LQQQQLALQLELEMQ------EKERQRI----QELQRAQEQLGKEMRMNMENLVRNEDIL 130
+ A QL E Q E+ERQR+ +E +R Q + + +R E L + E
Sbjct: 2507 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2566
Query: 131 HSEEATL 137
+E L
Sbjct: 2567 RQQEELL 2573
Score = 31.6 bits (70), Expect = 0.38
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 55 AKLERERELALMEQEMMERL-KAEELLL--QQQQLALQLELEMQEKERQRIQELQRAQEQ 111
AK + ERE ++Q M E + + EE + QQQ+ ++Q EL+ + + + + Q +
Sbjct: 1368 AKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE 1427
Query: 112 LGKEMRMNMENLVR 125
+ R+ +E +R
Sbjct: 1428 AAERSRLRIEEEIR 1441
Score = 31.6 bits (70), Expect = 0.38
Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ-LELEMQEKERQRIQEL 105
E RQ++ A E ER A +E+ R +AE+ +Q QLA + + +Q +E+ +
Sbjct: 1985 EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2044
Query: 106 QRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELD 162
Q+ +++L + ++ L + + + + ++R A + +VEE +
Sbjct: 2045 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2101
Score = 31.6 bits (70), Expect = 0.38
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 45 TMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE 104
T+E RQ+ ER RE + E+L+ E LLQ L+ E ++ Q +QE
Sbjct: 2419 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-----LKSEEMQTVQQEQLLQE 2473
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLD 138
Q Q+ E ++L++ E + E+A L+
Sbjct: 2474 TQALQQSFLSE----KDSLLQRERFIEQEKAKLE 2503
Score = 31.2 bits (69), Expect = 0.49
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 56 KLERERELALMEQEMMERLKAEELL----LQQQQLALQLELEMQEKERQRIQELQRAQEQ 111
K E E EL + + L+++E +Q+QLA + E +E E +R+Q+ A+E+
Sbjct: 1927 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE-ERVQKSLAAEEE 1985
Query: 112 LGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
++ + +E + R +A ++ + L E +++ A L +E
Sbjct: 1986 AARQRKAALEEVER-------LKAKVEEARRLRERAEQESARQLQLAQE 2027
Score = 30.0 bits (66), Expect = 1.1
Identities = 19/83 (22%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E RQ+++A+ + R+ A E+ + E+L A + + +L + E+ ++EKE + + +
Sbjct: 1798 EAKRQRQLAEEDAARQRAEAERVLAEKLAA---IGEATRLKTEAEIALKEKEAENERLRR 1854
Query: 107 RAQEQLGKEMRMNMENLVRNEDI 129
A+++ + R+ + DI
Sbjct: 1855 LAEDEAFQRRRLEEQAAQHKADI 1877
Score = 29.6 bits (65), Expect = 1.4
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQL 112
E A+ E EL E+ E LQ++ +A+ E E+ Q+ E +RA+E+
Sbjct: 1554 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1613
Query: 113 GKEM 116
+E+
Sbjct: 1614 EREL 1617
Score = 28.9 bits (63), Expect = 2.4
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 54 MAKLERERELALMEQ-EMMERLKAEELLLQQQ--------QLALQLELEMQEKERQRIQE 104
+ ++E E LA ++ E ERL E L++Q Q Q E E +E +++ +E
Sbjct: 1327 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEE 1386
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
+ R +E + + + S EA + + AE ++R
Sbjct: 1387 VVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1431
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 47.8 bits (112), Expect = 5e-06
Identities = 31/98 (31%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ RQ++ + ER+R +A ME+ + +AEE + ++Q+ QLE + +++E +E Q
Sbjct: 2560 EQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQ 2619
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEA---TLDSGK 141
R +EQL + L +E++ S+ A TL +G+
Sbjct: 2620 RLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGR 2657
Score = 42.0 bits (97), Expect = 3e-04
Identities = 40/127 (31%), Positives = 59/127 (46%), Gaps = 7/127 (5%)
Query: 16 QGLAEVARVRPVDPIEYLALWIYKYKENVTM-----EQLRQKEMAKLERERELALMEQEM 70
Q AE R R E L W K E + + E +QK +A+ E E++ E+E
Sbjct: 1642 QQQAEAERAREEAERE-LERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREA 1700
Query: 71 MERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
R KAEE ++Q++LA Q ELE Q + + + + A EQ +R E + +L
Sbjct: 1701 RRRGKAEEQAVRQRELAEQ-ELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLL 1759
Query: 131 HSEEATL 137
E A L
Sbjct: 1760 EEELARL 1766
Score = 38.9 bits (89), Expect = 0.002
Identities = 35/125 (28%), Positives = 61/125 (48%), Gaps = 13/125 (10%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-- 104
+ +RQ+E+A+ E E++ L E +RL AE Q+ + L+ E E E++RQ ++E
Sbjct: 1709 QAVRQRELAEQELEKQRQLAEGTAQQRLAAE-----QELIRLRAETEQGEQQRQLLEEEL 1763
Query: 105 --LQR---AQEQLGKEMRMNMENL-VRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRV 158
LQR A Q +E+ + + E +L S+ + ++ +E S + R
Sbjct: 1764 ARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRF 1823
Query: 159 EELDE 163
EL E
Sbjct: 1824 RELAE 1828
Score = 37.0 bits (84), Expect = 0.009
Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 1/81 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
KE +E RQ+++A E ER E+ + + L AEE +Q++ AL+ ++ K +
Sbjct: 1989 KEQAELEAARQRQLAA-EEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2047
Query: 101 RIQELQRAQEQLGKEMRMNME 121
+ +RA+++ +++++ E
Sbjct: 2048 ARRLRERAEQESARQLQLAQE 2068
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/93 (30%), Positives = 56/93 (60%), Gaps = 8/93 (8%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQL--ELEMQEKERQRIQE 104
E+LR++ + +R+R+ E E+ R+KAE +++Q ALQ EL +Q +E +R
Sbjct: 1524 ERLRRQVQDESQRKRQA---EVELASRVKAEAEAAREKQRALQALEELRLQAEEAER--R 1578
Query: 105 LQRAQEQLGKEMRMNMENLVRN-EDILHSEEAT 136
L++A+ + +++++ +E R+ E L S+ A+
Sbjct: 1579 LRQAEVERARQVQVALETAQRSAEAELQSKRAS 1611
Score = 35.4 bits (80), Expect = 0.026
Identities = 28/86 (32%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQ----EMMERLKAE-ELLLQQQQLALQLELEMQ 95
+E + QL ++++A+ E L E+ + RLKAE ELL QQ++LA + +Q
Sbjct: 2315 QEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQ 2374
Query: 96 EKERQRIQELQRAQEQLGKEMRMNME 121
E + Q Q+L A+E G + + E
Sbjct: 2375 EDKEQMAQQL--AEETQGFQRTLEAE 2398
Score = 34.7 bits (78), Expect = 0.044
Identities = 31/114 (27%), Positives = 52/114 (45%), Gaps = 8/114 (7%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQ + + A+ E+ EQE R +AE+ L+Q+Q A E+E +K ++ +
Sbjct: 2150 EQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQ-AADAEMEKHKKFAEQTLRQK 2208
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
EQ +R+ +E +++L E L + T A A S+VEE
Sbjct: 2209 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA-------ARQRSQVEE 2255
Score = 34.3 bits (77), Expect = 0.058
Identities = 27/103 (26%), Positives = 47/103 (45%), Gaps = 15/103 (14%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEE----LLLQQQQLALQLELEMQ------- 95
E R +E A+ E R+L L ++ +RL+AEE +QQ++ LQ L+ +
Sbjct: 2047 EARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQL 2106
Query: 96 ----EKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
E R+ +E + A+ Q +E + + E + S E
Sbjct: 2107 RGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAE 2149
Score = 34.3 bits (77), Expect = 0.058
Identities = 28/94 (29%), Positives = 55/94 (58%), Gaps = 5/94 (5%)
Query: 35 LWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEEL-LLQQQQLALQLELE 93
L I + + + E+LR+ +A+LERE+E E ++++ LK+EE+ +QQ+QL + +
Sbjct: 2461 LEIQRQQSDHDAERLREA-IAELEREKEKLQQEAKLLQ-LKSEEMQTVQQEQLLQETQAL 2518
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNMENLVRNE 127
Q ++ LQR E+ ++ + +E L ++E
Sbjct: 2519 QQSFLSEKDSLLQR--ERFIEQEKAKLEQLFQDE 2550
Score = 32.7 bits (73), Expect = 0.17
Identities = 32/127 (25%), Positives = 57/127 (44%), Gaps = 28/127 (22%)
Query: 39 KYKENVTMEQLRQKEMAKLEREREL---------------ALMEQEM---MERLKAEELL 80
K ++ + QL+ +EM +++E+ L +L+++E E+ K E+L
Sbjct: 2488 KLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLF 2547
Query: 81 LQQQQLALQLELEMQ------EKERQRI----QELQRAQEQLGKEMRMNMENLVRNEDIL 130
+ A QL E Q E+ERQR+ +E +R Q + + +R E L + E
Sbjct: 2548 QDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR 2607
Query: 131 HSEEATL 137
+E L
Sbjct: 2608 RQQEELL 2614
Score = 31.6 bits (70), Expect = 0.38
Identities = 20/74 (27%), Positives = 39/74 (52%), Gaps = 3/74 (4%)
Query: 55 AKLERERELALMEQEMMERL-KAEELLL--QQQQLALQLELEMQEKERQRIQELQRAQEQ 111
AK + ERE ++Q M E + + EE + QQQ+ ++Q EL+ + + + + Q +
Sbjct: 1409 AKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAE 1468
Query: 112 LGKEMRMNMENLVR 125
+ R+ +E +R
Sbjct: 1469 AAERSRLRIEEEIR 1482
Score = 31.6 bits (70), Expect = 0.38
Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 1/117 (0%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQ-LELEMQEKERQRIQEL 105
E RQ++ A E ER A +E+ R +AE+ +Q QLA + + +Q +E+ +
Sbjct: 2026 EAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAV 2085
Query: 106 QRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELD 162
Q+ +++L + ++ L + + + + ++R A + +VEE +
Sbjct: 2086 QQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2142
Score = 31.6 bits (70), Expect = 0.38
Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 45 TMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE 104
T+E RQ+ ER RE + E+L+ E LLQ L+ E ++ Q +QE
Sbjct: 2460 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ-----LKSEEMQTVQQEQLLQE 2514
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLD 138
Q Q+ E ++L++ E + E+A L+
Sbjct: 2515 TQALQQSFLSE----KDSLLQRERFIEQEKAKLE 2544
Score = 31.2 bits (69), Expect = 0.49
Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 12/109 (11%)
Query: 56 KLERERELALMEQEMMERLKAEELL----LQQQQLALQLELEMQEKERQRIQELQRAQEQ 111
K E E EL + + L+++E +Q+QLA + E +E E +R+Q+ A+E+
Sbjct: 1968 KAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAE-ERVQKSLAAEEE 2026
Query: 112 LGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEE 160
++ + +E + R +A ++ + L E +++ A L +E
Sbjct: 2027 AARQRKAALEEVER-------LKAKVEEARRLRERAEQESARQLQLAQE 2068
Score = 30.0 bits (66), Expect = 1.1
Identities = 19/83 (22%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E RQ+++A+ + R+ A E+ + E+L A + + +L + E+ ++EKE + + +
Sbjct: 1839 EAKRQRQLAEEDAARQRAEAERVLAEKLAA---IGEATRLKTEAEIALKEKEAENERLRR 1895
Query: 107 RAQEQLGKEMRMNMENLVRNEDI 129
A+++ + R+ + DI
Sbjct: 1896 LAEDEAFQRRRLEEQAAQHKADI 1918
Score = 29.6 bits (65), Expect = 1.4
Identities = 18/64 (28%), Positives = 31/64 (48%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQL 112
E A+ E EL E+ E LQ++ +A+ E E+ Q+ E +RA+E+
Sbjct: 1595 ETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEA 1654
Query: 113 GKEM 116
+E+
Sbjct: 1655 EREL 1658
Score = 28.9 bits (63), Expect = 2.4
Identities = 25/105 (23%), Positives = 46/105 (43%), Gaps = 9/105 (8%)
Query: 54 MAKLERERELALMEQ-EMMERLKAEELLLQQQ--------QLALQLELEMQEKERQRIQE 104
+ ++E E LA ++ E ERL E L++Q Q Q E E +E +++ +E
Sbjct: 1368 LRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEE 1427
Query: 105 LQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
+ R +E + + + S EA + + AE ++R
Sbjct: 1428 VVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAER 1472
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 47.0 bits (110), Expect = 9e-06
Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 5/104 (4%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKA-----EELLLQQQQLALQLELE 93
K KE E+ RQ+E E ER ++E +RL+A E+ LQ+++L L+ + +
Sbjct: 616 KIKEQRERERQRQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQ 675
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATL 137
E+ER + L+R + ++ +E R E + R + L ++ L
Sbjct: 676 RLERERMERERLERERMRVERERRKEQERIHREREELRRQQEQL 719
Score = 40.0 bits (92), Expect = 0.001
Identities = 40/133 (30%), Positives = 63/133 (47%), Gaps = 22/133 (16%)
Query: 39 KYKENVTMEQLRQKEMAKLEREREL-ALMEQEMMERLKAEELLLQQQQLALQLE-LEMQE 96
+ +E E R++E + ERE+ L A E++ RL+ E L L+ Q+ L+ E +E +
Sbjct: 627 RQREREIRETERRREREQREREQRLEAFHERKEKARLQRERLQLECQRQRLERERMERER 686
Query: 97 KERQRI-----------------QELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDS 139
ER+R+ +EL+R QEQL E R D+ ++A
Sbjct: 687 LERERMRVERERRKEQERIHREREELRRQQEQLRYEQERRPGR--RPYDLDRRDDAYWPE 744
Query: 140 GKTLAEISDRYGA 152
GK +A + DRY A
Sbjct: 745 GKRVA-MEDRYRA 756
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 46.6 bits (109), Expect = 1e-05
Identities = 22/71 (30%), Positives = 46/71 (64%)
Query: 48 QLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQR 107
Q +Q+++ + + + L +QE +++ E+ LLQQQQ LQ + +Q++E+ + Q+ Q+
Sbjct: 171 QQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQ 230
Query: 108 AQEQLGKEMRM 118
QEQL ++ ++
Sbjct: 231 QQEQLQQQQQL 241
Score = 43.1 bits (100), Expect = 1e-04
Identities = 27/100 (27%), Positives = 57/100 (57%), Gaps = 4/100 (4%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQ-EL 105
+Q Q+++++L++E+ ++ QE+ L +L+ QQQQL Q E Q ++Q+ Q +
Sbjct: 123 QQDGQQQLSQLQQEKHQSVHHQELKPEL---QLMHQQQQLQPQQVQEQQRLQQQQEQLQT 179
Query: 106 QRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAE 145
Q+AQEQ + + ++ V+ + +L ++ L + L +
Sbjct: 180 QQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQ 219
Score = 43.1 bits (100), Expect = 1e-04
Identities = 35/129 (27%), Positives = 65/129 (50%), Gaps = 31/129 (24%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELL------LQQQQ--------------- 85
+QL +++ A+L+++ L L +QE +++ + ++LL LQQQQ
Sbjct: 264 QQLLEQQQAQLQQQ--LLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVE 321
Query: 86 -------LALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLD 138
L + ELE Q +E +R QEL+R QEQ ++++ E L + E L ++ L+
Sbjct: 322 LELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKL-QEELQQLEQQLEQQQQQLE 380
Query: 139 SGKTLAEIS 147
+ E++
Sbjct: 381 QQEVQLELT 389
Score = 41.2 bits (95), Expect = 5e-04
Identities = 24/97 (24%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
K Q + E+ + ++++L + + +RL+ ++ LQ QQ Q L+ QE+ +Q
Sbjct: 137 KHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQ 196
Query: 101 RIQE---LQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
++QE LQ+ QEQL ++ + + ++ + +E
Sbjct: 197 QVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQE 233
Score = 40.8 bits (94), Expect = 6e-04
Identities = 25/91 (27%), Positives = 57/91 (62%), Gaps = 13/91 (14%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQE--------MMERLKAEELLLQQQQLAL 88
+ + +E + +Q +Q++ +L+++++L L++Q+ ++ + ++ LL+QQQ L
Sbjct: 216 LLQQQEQLQQQQFQQQQ-EQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQL 274
Query: 89 QLELEMQEKE----RQRIQELQRAQEQLGKE 115
Q +L +Q++E +Q+ Q LQ+ QEQL ++
Sbjct: 275 QQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQ 305
Score = 40.4 bits (93), Expect = 8e-04
Identities = 20/81 (24%), Positives = 49/81 (60%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
EQL+Q+++ + + + + +Q+ + + ++LLL QQQ LQ +L Q++ + + Q L+
Sbjct: 209 EQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLE 268
Query: 107 RAQEQLGKEMRMNMENLVRNE 127
+ Q QL +++ + + ++ +
Sbjct: 269 QQQAQLQQQLLLQQQEQLQQQ 289
Score = 38.9 bits (89), Expect = 0.002
Identities = 22/105 (20%), Positives = 58/105 (55%), Gaps = 4/105 (3%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQEMM----ERLKAEELLLQQQQLALQLEL 92
+ + +E + +Q +++++ + + + + + EQ+++ E+L+ ++LL QQ+QL Q
Sbjct: 170 LQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQ 229
Query: 93 EMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATL 137
+ QE+ +Q+ Q L Q+ ++ + + + +L ++A L
Sbjct: 230 QQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQL 274
Score = 38.5 bits (88), Expect = 0.003
Identities = 24/94 (25%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
++ V +QL Q++ +L++++ L EQ ++ + ++ LQQQQ L L+ + Q ++
Sbjct: 195 QQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQ-- 252
Query: 101 RIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
Q LQ+ Q QL +++ + ++ + +L +E
Sbjct: 253 --QLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQE 284
Score = 35.8 bits (81), Expect = 0.020
Identities = 23/91 (25%), Positives = 53/91 (58%), Gaps = 7/91 (7%)
Query: 46 MEQLRQKEMAKLERERELALMEQEMMERLKAEE--LLLQQQQLALQLE----LEMQEKER 99
M Q +Q + +++ ++ L +QE ++ +A+E +L QQ+QL Q++ L+ Q+++
Sbjct: 153 MHQQQQLQPQQVQEQQRLQ-QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQL 211
Query: 100 QRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
Q+ Q LQ+ ++ ++ + E L + + +L
Sbjct: 212 QQQQLLQQQEQLQQQQFQQQQEQLQQQQQLL 242
Score = 35.0 bits (79), Expect = 0.034
Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 7/81 (8%)
Query: 42 ENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQL---ALQLELEMQE-- 96
E E RQ+E+ + + +R+L L QE +++L+ ++L QQQQL +QLEL E
Sbjct: 336 EQQRQELERQQELERQQEQRQLQLKLQEELQQLE-QQLEQQQQQLEQQEVQLELTPVELG 394
Query: 97 KERQRIQ-ELQRAQEQLGKEM 116
++Q +Q EL Q +L E+
Sbjct: 395 AQQQEVQLELTPVQPELQLEL 415
Score = 32.0 bits (71), Expect = 0.29
Identities = 16/54 (29%), Positives = 33/54 (61%)
Query: 58 ERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQ 111
+RE +L +EQ+ + + + LQQ Q L+L+ + Q+ +Q++ +LQ+ + Q
Sbjct: 86 QRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQ 139
Score = 32.0 bits (71), Expect = 0.29
Identities = 23/74 (31%), Positives = 40/74 (54%), Gaps = 12/74 (16%)
Query: 46 MEQLRQK--EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQ 103
+EQ RQ+ +LER++E ++ ++ E L QQL QLE + Q+ E+Q +Q
Sbjct: 335 LEQQRQELERQQELERQQEQRQLQLKLQEEL---------QQLEQQLEQQQQQLEQQEVQ 385
Query: 104 ELQRAQEQLGKEMR 117
L+ +LG + +
Sbjct: 386 -LELTPVELGAQQQ 398
Score = 29.3 bits (64), Expect = 1.9
Identities = 26/95 (27%), Positives = 51/95 (53%), Gaps = 5/95 (5%)
Query: 26 PVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQ-QQ 84
P++P E + + ++ EQ +++ +LER++EL +++ +LK +E L Q +Q
Sbjct: 311 PLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQ 370
Query: 85 QL---ALQLELEMQEKERQRIQELQRAQEQLGKEM 116
QL QLE + + E + EL Q+++ E+
Sbjct: 371 QLEQQQQQLEQQEVQLELTPV-ELGAQQQEVQLEL 404
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 45.4 bits (106), Expect = 3e-05
Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 4/77 (5%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
+E EQ RQ + RE+E E+E+ ER KA L LQ++QL +LE + +++E+Q
Sbjct: 708 REQERREQERQLAEQERRREQERLQAERELQEREKA--LRLQKEQLQRELEEKKKKEEQQ 765
Query: 101 RIQE--LQRAQEQLGKE 115
R+ E LQ QE+ KE
Sbjct: 766 RLAERQLQEEQEKKAKE 782
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 4/88 (4%)
Query: 41 KENVTMEQLRQKEMAK-LERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQE--K 97
K+ E+LR+ AK L +RE EQE E+ + E+ +Q++ + +L QE +
Sbjct: 667 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 726
Query: 98 ERQRIQELQRAQEQLGKEMRMNMENLVR 125
E++R+Q + QE+ K +R+ E L R
Sbjct: 727 EQERLQAERELQER-EKALRLQKEQLQR 753
Score = 35.8 bits (81), Expect = 0.020
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQ----QLALQLELEMQEKERQ-R 101
EQ Q+ + RE+E E+ ER + E L +Q+ Q LQ E E+QE+E+ R
Sbjct: 686 EQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALR 745
Query: 102 IQELQRAQEQLGKEMRMNMENLVRNE 127
+Q+ Q +E K+ + + L +
Sbjct: 746 LQKEQLQRELEEKKKKEEQQRLAERQ 771
Score = 33.5 bits (75), Expect = 0.099
Identities = 28/98 (28%), Positives = 49/98 (50%), Gaps = 4/98 (4%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMME--RLKAEELLLQQQQLALQLELEMQEKE 98
KE +E LR+KE A+ R +++ ++ +E +LK EE L + Q ++E +EK+
Sbjct: 537 KERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKK 596
Query: 99 RQRIQELQRAQE--QLGKEMRMNMENLVRNEDILHSEE 134
+Q Q+ + E + KE R+ E + EE
Sbjct: 597 KQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 634
Score = 33.5 bits (75), Expect = 0.099
Identities = 28/115 (24%), Positives = 58/115 (50%), Gaps = 10/115 (8%)
Query: 39 KYKENVTMEQLRQKEMAKLE--RERELALMEQEMMERLKAEEL-----LLQQQQLALQLE 91
K E V + +++E +L ++ E QE++++ K EE + ++LA Q E
Sbjct: 630 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 689
Query: 92 LEMQE---KERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTL 143
E +E +E++R ++ +R QE+ +E ++ + R ++ L +E + K L
Sbjct: 690 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 744
Score = 29.6 bits (65), Expect = 1.4
Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-LQRAQEQ 111
E AK ER E ++ ++++ E +Q++ A +L QE+E +R QE LQ+ +E+
Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 670
Query: 112 LGKEMRMNME 121
+ +R E
Sbjct: 671 EQERLRKAAE 680
Score = 28.5 bits (62), Expect = 3.2
Identities = 18/81 (22%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
K N + + + ER+R L +E E+L+ +++ +++ +++L+ +E+ R+
Sbjct: 521 KRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK 580
Query: 101 RIQELQRAQEQLGKEMRMNME 121
+Q +R EQ+ +E + +E
Sbjct: 581 VLQARERV-EQMKEEKKKQIE 600
Score = 26.9 bits (58), Expect = 9.3
Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 8/101 (7%)
Query: 36 WIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQ 95
W+ + +E ++L QK+ + E+ER E + + + +E Q+++ + E E +
Sbjct: 650 WLQQEEEERRHQELLQKKKEE-EQERLRKAAEAKRLAEQREQERREQERREQERREQERR 708
Query: 96 EKER-QRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEA 135
E+ER + QE Q A++ E R E L ++ E+A
Sbjct: 709 EQERRE--QERQLAEQ----ERRREQERLQAERELQEREKA 743
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 45.4 bits (106), Expect = 3e-05
Identities = 31/77 (40%), Positives = 46/77 (59%), Gaps = 4/77 (5%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
+E EQ RQ + RE+E E+E+ ER KA L LQ++QL +LE + +++E+Q
Sbjct: 704 REQERREQERQLAEQERRREQERLQAERELQEREKA--LRLQKEQLQRELEEKKKKEEQQ 761
Query: 101 RIQE--LQRAQEQLGKE 115
R+ E LQ QE+ KE
Sbjct: 762 RLAERQLQEEQEKKAKE 778
Score = 36.2 bits (82), Expect = 0.015
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 4/88 (4%)
Query: 41 KENVTMEQLRQKEMAK-LERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQE--K 97
K+ E+LR+ AK L +RE EQE E+ + E+ +Q++ + +L QE +
Sbjct: 663 KKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRR 722
Query: 98 ERQRIQELQRAQEQLGKEMRMNMENLVR 125
E++R+Q + QE+ K +R+ E L R
Sbjct: 723 EQERLQAERELQER-EKALRLQKEQLQR 749
Score = 35.8 bits (81), Expect = 0.020
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 5/86 (5%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQ----QLALQLELEMQEKERQ-R 101
EQ Q+ + RE+E E+ ER + E L +Q+ Q LQ E E+QE+E+ R
Sbjct: 682 EQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALR 741
Query: 102 IQELQRAQEQLGKEMRMNMENLVRNE 127
+Q+ Q +E K+ + + L +
Sbjct: 742 LQKEQLQRELEEKKKKEEQQRLAERQ 767
Score = 34.7 bits (78), Expect = 0.044
Identities = 29/100 (29%), Positives = 50/100 (50%), Gaps = 4/100 (4%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMME--RLKAEELLLQQQQLALQLELEMQE 96
K KE +E LR+KE A+ R +++ ++ +E +LK EE L + Q ++E +E
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 97 KERQRIQELQRAQE--QLGKEMRMNMENLVRNEDILHSEE 134
K++Q Q+ + E + KE R+ E + EE
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630
Score = 33.5 bits (75), Expect = 0.099
Identities = 28/115 (24%), Positives = 58/115 (50%), Gaps = 10/115 (8%)
Query: 39 KYKENVTMEQLRQKEMAKLE--RERELALMEQEMMERLKAEEL-----LLQQQQLALQLE 91
K E V + +++E +L ++ E QE++++ K EE + ++LA Q E
Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 685
Query: 92 LEMQE---KERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTL 143
E +E +E++R ++ +R QE+ +E ++ + R ++ L +E + K L
Sbjct: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKAL 740
Score = 29.6 bits (65), Expect = 1.4
Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQE-LQRAQEQ 111
E AK ER E ++ ++++ E +Q++ A +L QE+E +R QE LQ+ +E+
Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE 666
Query: 112 LGKEMRMNME 121
+ +R E
Sbjct: 667 EQERLRKAAE 676
Score = 26.9 bits (58), Expect = 9.3
Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 8/101 (7%)
Query: 36 WIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQ 95
W+ + +E ++L QK+ + E+ER E + + + +E Q+++ + E E +
Sbjct: 646 WLQQEEEERRHQELLQKKKEE-EQERLRKAAEAKRLAEQREQERREQERREQERREQERR 704
Query: 96 EKER-QRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEA 135
E+ER + QE Q A++ E R E L ++ E+A
Sbjct: 705 EQERRE--QERQLAEQ----ERRREQERLQAERELQEREKA 739
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 44.7 bits (104), Expect = 4e-05
Identities = 39/133 (29%), Positives = 70/133 (52%), Gaps = 11/133 (8%)
Query: 43 NVTMEQLRQKEMAKLERERE-LALMEQEMMERLKAEELLLQQQQLALQLELEMQEK---- 97
++ QL ++++ +LE++RE E+E ER +AEE Q++ L+ E + +EK
Sbjct: 267 SIKKRQLERQKLQELEQQREEQKRREKEAEERQRAEERK-QKELEELERERKREEKLRKR 325
Query: 98 -ERQRIQELQRAQEQLGK----EMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGA 152
++QR +EL+R Q++L K E + E + E L + L S + +AE+ R A
Sbjct: 326 EQKQRDRELRRNQKKLEKLQAEEQKQLQEKIKLEERKLLLAQRNLQSIRLIAELLSRAKA 385
Query: 153 PNLSRVEELDEPM 165
L E+ +E +
Sbjct: 386 VKLREQEQKEEKL 398
Score = 34.7 bits (78), Expect = 0.044
Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 12/88 (13%)
Query: 47 EQLRQKEMAKLERERELALMEQ---------EMMERLKAEELLLQQQQLALQLELEMQEK 97
EQ + +E KLE ER+L L ++ E++ R KA + L +Q+Q +L L+ QE
Sbjct: 348 EQKQLQEKIKLE-ERKLLLAQRNLQSIRLIAELLSRAKAVK-LREQEQKEEKLRLQQQE- 404
Query: 98 ERQRIQELQRAQEQLGKEMRMNMENLVR 125
ER+R+QE + + + KE + ++ R
Sbjct: 405 ERRRLQEAELRRVEEEKERALGLQRKER 432
Score = 32.7 bits (73), Expect = 0.17
Identities = 23/63 (36%), Positives = 35/63 (55%), Gaps = 7/63 (11%)
Query: 57 LERERELALMEQEMMERLKAEELLLQQQQLALQL---ELEMQEKERQRIQELQRAQEQLG 113
L R + + L EQE E E+L LQQQ+ +L EL E+E++R LQR + +L
Sbjct: 380 LSRAKAVKLREQEQKE----EKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELR 435
Query: 114 KEM 116
+ +
Sbjct: 436 ERL 438
Score = 28.5 bits (62), Expect = 3.2
Identities = 18/56 (32%), Positives = 34/56 (60%), Gaps = 5/56 (8%)
Query: 48 QLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE-RQRI 102
+LR++E ++E +L L +QE RL+ EL +++ L L+ +E+E R+R+
Sbjct: 387 KLREQE----QKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRERL 438
>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
sapiens]
Length = 551
Score = 44.7 bits (104), Expect = 4e-05
Identities = 30/111 (27%), Positives = 59/111 (53%), Gaps = 7/111 (6%)
Query: 46 MEQLRQKEMAKLERERELALMEQEMMERL-----KAEELLLQQQQLALQLELEMQEKERQ 100
MEQL+++++ +ER ++ L Q ++R+ K + LL Q++LA Q+ +E +K+
Sbjct: 290 MEQLQEEDLKDMERRQQQKLKMQAEIKRINDENQKQKAELLAQEKLADQMVMEFTKKKMA 349
Query: 101 RIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDS--GKTLAEISDR 149
R E + QE++ +E + L ++ +A D+ K E++DR
Sbjct: 350 REAEFEAEQERIRREKEKEIARLRAMQEKAQDYQAEQDALRAKRNQEVADR 400
Score = 38.5 bits (88), Expect = 0.003
Identities = 30/106 (28%), Positives = 55/106 (51%), Gaps = 8/106 (7%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
++ + E+ R +M ++ER++ ++ QE +ER + EE + ++Q+ Q +E ++ER
Sbjct: 218 QKELDTEEKRLDQMMEVERQK--SIQRQEELERKRREERIRGRRQIVEQ--MEKNQEERS 273
Query: 101 RIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEI 146
+ E QR QE KE + ++ ED+ E K AEI
Sbjct: 274 LLAE-QREQE---KEQMLEYMEQLQEEDLKDMERRQQQKLKMQAEI 315
Score = 36.2 bits (82), Expect = 0.015
Identities = 36/162 (22%), Positives = 64/162 (39%), Gaps = 21/162 (12%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLAL-------- 88
I K KE V + ++ ++ +ER L+++ R++ EE L ++ L
Sbjct: 148 IMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKDMSKIILNAKCHAIR 207
Query: 89 ----------QLELEMQEKERQRIQELQRA---QEQLGKEMRMNMENLVRNEDILHSEEA 135
Q EL+ +EK ++ E++R Q Q E + E + I+ E
Sbjct: 208 DAQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQEELERKRREERIRGRRQIVEQMEK 267
Query: 136 TLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL 177
+ LAE ++ L +E+L E D+ Q L
Sbjct: 268 NQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDMERRQQQKL 309
Score = 35.4 bits (80), Expect = 0.026
Identities = 25/66 (37%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 53 EMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQL 112
E + E+E+ L MEQ E LK E QQQ+L +Q E++ E Q+ + AQE+L
Sbjct: 277 EQREQEKEQMLEYMEQLQEEDLKDMERR-QQQKLKMQAEIKRINDENQKQKAELLAQEKL 335
Query: 113 GKEMRM 118
+M M
Sbjct: 336 ADQMVM 341
Score = 30.0 bits (66), Expect = 1.1
Identities = 22/93 (23%), Positives = 48/93 (51%), Gaps = 8/93 (8%)
Query: 50 RQKEMAKLERERELA-------LMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRI 102
RQ+E+ + RE + ME+ ER E Q+++ L+ ++QE++ + +
Sbjct: 242 RQEELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEEDLKDM 301
Query: 103 QELQRAQEQLGKEM-RMNMENLVRNEDILHSEE 134
+ Q+ + ++ E+ R+N EN + ++L E+
Sbjct: 302 ERRQQQKLKMQAEIKRINDENQKQKAELLAQEK 334
Score = 26.9 bits (58), Expect = 9.3
Identities = 28/129 (21%), Positives = 57/129 (44%), Gaps = 10/129 (7%)
Query: 44 VTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQ 103
+T + +R+ + + E ++ E ER+K +L +++L + + +EKE
Sbjct: 82 ITRDMVRELIVPTEDPSGESLIISPEEFERIKWASHVLTREELEARDQAFKKEKEATMDA 141
Query: 104 ELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDE 163
+ R + KEM N N+ + EE + + L + +++ + + EEL +
Sbjct: 142 VMTRKKIMKQKEMVWN-----NNKKLSDLEEVAKERAQNLLQRANKL---RMEQEEELKD 193
Query: 164 PMFSDIALN 172
S I LN
Sbjct: 194 --MSKIILN 200
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 44.3 bits (103), Expect = 6e-05
Identities = 31/121 (25%), Positives = 62/121 (51%), Gaps = 7/121 (5%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E++R++E K+ R+ E+ ++E M R EE++ ++++ +LE +M E+E+ R QE +
Sbjct: 309 EKIREQE-EKMRRQEEMMWEKEEKMRR--QEEMMWEKEEKIRELEEKMHEQEKIREQEEK 365
Query: 107 RAQEQLGKEMRMNMENLVR----NEDILHSEEATLDSGKTLAEISDRYGAPNLSRVEELD 162
R +E+ +E E + E I EE + + + E ++ G E+ +
Sbjct: 366 RQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEE 425
Query: 163 E 163
E
Sbjct: 426 E 426
Score = 39.3 bits (90), Expect = 0.002
Identities = 25/94 (26%), Positives = 54/94 (57%), Gaps = 2/94 (2%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQ 100
+E + ++ + +E K RE+E + EQE M + + EE + +Q+ + E +MQE+E +
Sbjct: 431 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ-EQEEKMGEQEGKMCEQEAKMQEQEEK 489
Query: 101 RIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
++ ++ +EQ K++R E + E+++ +E
Sbjct: 490 MRRQEEKIREQ-EKKIREQEEKIREQEEMMQEQE 522
Score = 38.5 bits (88), Expect = 0.003
Identities = 29/100 (29%), Positives = 56/100 (56%), Gaps = 8/100 (8%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEM--QEKE 98
+E + ++ RQ++ AK+ R+ E + EQE R + EE++ +Q++ + E +M QE+E
Sbjct: 369 EEKIREQEKRQEQEAKMWRQEE-KIREQEEKIR-EQEEMMQEQEEKMGEQEEKMWEQEEE 426
Query: 99 RQRIQELQRAQE----QLGKEMRMNMENLVRNEDILHSEE 134
Q +E R QE + K++R E + E+++ +E
Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466
Score = 38.1 bits (87), Expect = 0.004
Identities = 34/124 (27%), Positives = 60/124 (48%), Gaps = 13/124 (10%)
Query: 34 ALWIYKYKENVTMEQLRQKEMAKLERERELALMEQ--------EMMERLKAEELLLQQQQ 85
AL + Y+ +T E+L++K AKL+ + +L E+ E+ +L+ +LLL QQQ
Sbjct: 192 ALSLELYRNTITDEELKEKN-AKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQ 250
Query: 86 LALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAE 145
LQ E + KE Q + + Q Q+ + N N + E + EE + + + E
Sbjct: 251 --LQAEADHLGKELQSVS--AKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQE 306
Query: 146 ISDR 149
++
Sbjct: 307 QEEK 310
Score = 36.6 bits (83), Expect = 0.012
Identities = 24/87 (27%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Query: 35 LWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLE-LE 93
+W + K E++R++E E+E ++ E++M E + EE+ Q++++ Q E +
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWE--QEEEMQEQEEKMRRQEEKIR 442
Query: 94 MQEKERQRIQELQRAQEQLGKEMRMNM 120
QEK+ + +E R QE++ +E M
Sbjct: 443 EQEKKIREQEEKIREQEEMMQEQEEKM 469
Score = 36.6 bits (83), Expect = 0.012
Identities = 27/114 (23%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Query: 39 KYKENVTMEQLRQKEMAKLER---ERELALMEQEMMERLKAEELLLQQQQLALQLELEMQ 95
K +E M Q ++++M + E E+E + EQE R + EE + +Q++ + E +++
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR-RQEEKIREQEKKIREQEEKIR 456
Query: 96 EKERQRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
E+E ++ ++ EQ GK + + E + EE + K + E ++
Sbjct: 457 EQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEK 510
Score = 35.8 bits (81), Expect = 0.020
Identities = 22/82 (26%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Query: 41 KENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLE-LEMQEKER 99
+E + ++ + +E K RE+E + EQE M + + E++ Q++++ Q E ++ QE++
Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 546
Query: 100 QRIQELQRAQEQLGKEMRMNME 121
+R +E R QE ++ M+
Sbjct: 547 RRQEEKMREQEVRLRQQEEKMQ 568
Score = 35.4 bits (80), Expect = 0.026
Identities = 23/88 (26%), Positives = 48/88 (54%), Gaps = 2/88 (2%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
++ + +E + R +E + EQE R + EE + +Q+++ + E +M E+E + ++ +
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIR-EQEEKIREQEEMMQEQEEKMWEQEEKMCEQEE 537
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEE 134
+ QEQ ++MR E + E L +E
Sbjct: 538 KMQEQ-EEKMRRQEEKMREQEVRLRQQE 564
Score = 33.9 bits (76), Expect = 0.076
Identities = 25/103 (24%), Positives = 52/103 (50%), Gaps = 2/103 (1%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
E+ Q++ K+ R+ E + EQE R + EE + +Q+++ + E +M E+E + ++
Sbjct: 424 EEEMQEQEEKMRRQEE-KIREQEKKIR-EQEEKIREQEEMMQEQEEKMGEQEGKMCEQEA 481
Query: 107 RAQEQLGKEMRMNMENLVRNEDILHSEEATLDSGKTLAEISDR 149
+ QEQ K R + + + I EE + + + E ++
Sbjct: 482 KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 524
Score = 32.7 bits (73), Expect = 0.17
Identities = 17/73 (23%), Positives = 42/73 (57%)
Query: 39 KYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKE 98
+ +E + ++ + +E + RE+E + EQE + E++ Q++++ Q E +++E
Sbjct: 492 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Query: 99 RQRIQELQRAQEQ 111
+ R QE++ Q++
Sbjct: 552 KMREQEVRLRQQE 564
Score = 30.0 bits (66), Expect = 1.1
Identities = 21/102 (20%), Positives = 51/102 (50%), Gaps = 14/102 (13%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKA--------EELLLQQQQLALQLELEMQEKE 98
E++R++E E+E ++ +E++M E+ K EE +++Q+ + E +M +E
Sbjct: 330 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE 389
Query: 99 R------QRIQELQRAQEQLGKEMRMNMENLVRNEDILHSEE 134
++I+E + ++ ++M E + E+ + +E
Sbjct: 390 EKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE 431
Score = 28.9 bits (63), Expect = 2.4
Identities = 17/74 (22%), Positives = 44/74 (59%), Gaps = 1/74 (1%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQE 96
I + ++ + ++ + +E ++ +E+E + EQE + + EE + +Q++ + E +M+E
Sbjct: 497 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQE-EKMCEQEEKMQEQEEKMRRQEEKMRE 555
Query: 97 KERQRIQELQRAQE 110
+E + Q+ ++ QE
Sbjct: 556 QEVRLRQQEEKMQE 569
>gi|224028248 non-POU domain containing, octamer-binding isoform 2
[Homo sapiens]
Length = 382
Score = 43.9 bits (102), Expect = 7e-05
Identities = 24/66 (36%), Positives = 39/66 (59%), Gaps = 4/66 (6%)
Query: 51 QKEMAKLERERELALMEQEMMERL----KAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
+ EM E ++ LM Q++M R + EEL Q+ Q QLEL +E+ R+R +E++
Sbjct: 208 EMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMR 267
Query: 107 RAQEQL 112
R QE++
Sbjct: 268 RQQEEM 273
>gi|224028246 non-POU domain containing, octamer-binding isoform 1
[Homo sapiens]
Length = 471
Score = 43.9 bits (102), Expect = 7e-05
Identities = 24/66 (36%), Positives = 39/66 (59%), Gaps = 4/66 (6%)
Query: 51 QKEMAKLERERELALMEQEMMERL----KAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
+ EM E ++ LM Q++M R + EEL Q+ Q QLEL +E+ R+R +E++
Sbjct: 297 EMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMR 356
Query: 107 RAQEQL 112
R QE++
Sbjct: 357 RQQEEM 362
>gi|224028244 non-POU domain containing, octamer-binding isoform 1
[Homo sapiens]
Length = 471
Score = 43.9 bits (102), Expect = 7e-05
Identities = 24/66 (36%), Positives = 39/66 (59%), Gaps = 4/66 (6%)
Query: 51 QKEMAKLERERELALMEQEMMERL----KAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
+ EM E ++ LM Q++M R + EEL Q+ Q QLEL +E+ R+R +E++
Sbjct: 297 EMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMR 356
Query: 107 RAQEQL 112
R QE++
Sbjct: 357 RQQEEM 362
>gi|34932414 non-POU domain containing, octamer-binding isoform 1
[Homo sapiens]
Length = 471
Score = 43.9 bits (102), Expect = 7e-05
Identities = 24/66 (36%), Positives = 39/66 (59%), Gaps = 4/66 (6%)
Query: 51 QKEMAKLERERELALMEQEMMERL----KAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
+ EM E ++ LM Q++M R + EEL Q+ Q QLEL +E+ R+R +E++
Sbjct: 297 EMEMEAARHEHQVMLMRQDLMRRQEELRRMEELHNQEVQKRKQLELRQEEERRRREEEMR 356
Query: 107 RAQEQL 112
R QE++
Sbjct: 357 RQQEEM 362
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 43.9 bits (102), Expect = 7e-05
Identities = 41/143 (28%), Positives = 72/143 (50%), Gaps = 19/143 (13%)
Query: 44 VTMEQLRQKEMAKLERERELALMEQEMMERLKAEEL--LLQQQQLALQLELEMQEKERQR 101
+ E+ RQ + K + E+E +E+E +RL+ EEL ++++L L+ E QE+ER+R
Sbjct: 403 ILAEKRRQARLQKEQEEQER--VEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKR 460
Query: 102 IQELQRAQE-----QLGKEMRMNMEN---LVRNEDILHSEEATLDSGKTLAEISDRYGAP 153
+E ++ QE + G+E + E L ++ E+A ++ K AE R A
Sbjct: 461 QEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAE 520
Query: 154 NLSRVEELDEPMFSDIALNIDQD 176
+ R+E I L I+Q+
Sbjct: 521 QM-RLER------EQIMLQIEQE 536
Score = 34.3 bits (77), Expect = 0.058
Identities = 19/61 (31%), Positives = 39/61 (63%), Gaps = 5/61 (8%)
Query: 47 EQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQ 106
++ ++E A +E+++E A E R AE++ L+++Q+ LQ+E E E+ ++RI E+
Sbjct: 494 QEQEKQEKAMIEKQKEAA----ETKAREVAEQMRLEREQIMLQIEQERLER-KKRIDEIM 548
Query: 107 R 107
+
Sbjct: 549 K 549
Score = 29.6 bits (65), Expect = 1.4
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 19/129 (14%)
Query: 11 GACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERERELALMEQEM 70
G L +AE VR P Y+ L+ E +L +ER +E
Sbjct: 20 GTSLPGKIAEPGAVRTSQP---------NYRPQGMEGFLKSDERQRLAKERR-----EER 65
Query: 71 MERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNEDIL 130
+ L A E + ++Q +L+ E Q +ER R E QR +E + R +E + + L
Sbjct: 66 EKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQRED---QKRAAVEE--KRKQKL 120
Query: 131 HSEEATLDS 139
EE L++
Sbjct: 121 REEEERLEA 129
Score = 27.7 bits (60), Expect = 5.4
Identities = 15/47 (31%), Positives = 26/47 (55%)
Query: 37 IYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQ 83
I K KE + E +LERE+ + +EQE +ER K + ++++
Sbjct: 504 IEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKR 550
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.343
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,725,439
Number of Sequences: 37866
Number of extensions: 245937
Number of successful extensions: 7282
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 474
Number of HSP's successfully gapped in prelim test: 545
Number of HSP's that attempted gapping in prelim test: 2408
Number of HSP's gapped (non-prelim): 3653
length of query: 177
length of database: 18,247,518
effective HSP length: 95
effective length of query: 82
effective length of database: 14,650,248
effective search space: 1201320336
effective search space used: 1201320336
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.