Guide to the Human Genome
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Search of human proteins with 20149663

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20149663 coiled-coil domain containing 90B [Homo sapiens]
         (254 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20149663 coiled-coil domain containing 90B [Homo sapiens]          497   e-141
gi|72534716 coiled-coil domain containing 90A [Homo sapiens]          228   4e-60
gi|38570058 hypothetical protein LOC80129 [Homo sapiens]               42   7e-04
gi|4557701 keratin 17 [Homo sapiens]                                   39   0.003
gi|38044112 restin isoform b [Homo sapiens]                            39   0.004
gi|4506751 restin isoform a [Homo sapiens]                             39   0.004
gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]                39   0.004
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 39   0.006
gi|154354990 ankyrin repeat domain 26 [Homo sapiens]                   39   0.006
gi|4502443 dystonin isoform 1e precursor [Homo sapiens]                38   0.007
gi|169646281 coiled-coil domain containing 14 [Homo sapiens]           38   0.007
gi|149363642 coiled-coil domain containing 144A [Homo sapiens]         38   0.010
gi|27894337 keratin 20 [Homo sapiens]                                  37   0.017
gi|151101151 coiled-coil domain containing 2 isoform b [Homo sap...    37   0.017
gi|151101140 coiled-coil domain containing 2 isoform a [Homo sap...    37   0.017
gi|151105223 coiled-coil domain containing 2 isoform a [Homo sap...    37   0.017
gi|151105229 coiled-coil domain containing 2 isoform a [Homo sap...    37   0.017
gi|143770880 laminin, beta 4 [Homo sapiens]                            37   0.022
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         37   0.022
gi|42794779 myosin 18A isoform b [Homo sapiens]                        36   0.028
gi|28416946 myosin 18A isoform a [Homo sapiens]                        36   0.028
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    36   0.037
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom...    36   0.037
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    36   0.037
gi|198442834 coiled-coil domain containing 152 [Homo sapiens]          36   0.037
gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]                36   0.037
gi|15431310 keratin 14 [Homo sapiens]                                  35   0.048
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     35   0.048
gi|157388975 coiled-coil domain containing 99 [Homo sapiens]           35   0.048
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     35   0.063

>gi|20149663 coiled-coil domain containing 90B [Homo sapiens]
          Length = 254

 Score =  497 bits (1280), Expect = e-141
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MNSRQAWRLFLSQGRGDRWVSRPRGHFSPALRREFFTTTTKEGYDRRPVDITPLEQRKLT 60
           MNSRQAWRLFLSQGRGDRWVSRPRGHFSPALRREFFTTTTKEGYDRRPVDITPLEQRKLT
Sbjct: 1   MNSRQAWRLFLSQGRGDRWVSRPRGHFSPALRREFFTTTTKEGYDRRPVDITPLEQRKLT 60

Query: 61  FDTHALVQDLETHGFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLD 120
           FDTHALVQDLETHGFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLD
Sbjct: 61  FDTHALVQDLETHGFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLD 120

Query: 121 AIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDM 180
           AIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDM
Sbjct: 121 AIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDM 180

Query: 181 FTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVF 240
           FTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVF
Sbjct: 181 FTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASVF 240

Query: 241 TCLAIALGFYRFWK 254
           TCLAIALGFYRFWK
Sbjct: 241 TCLAIALGFYRFWK 254


>gi|72534716 coiled-coil domain containing 90A [Homo sapiens]
          Length = 359

 Score =  228 bits (581), Expect = 4e-60
 Identities = 117/229 (51%), Positives = 160/229 (69%), Gaps = 3/229 (1%)

Query: 28  SPAL---RREFFTTTTKEGYDRRPVDITPLEQRKLTFDTHALVQDLETHGFDKTQAETIV 84
           +PAL   RRE   +      +R+  D T    RKL FDTHALV  LE +GF   QAE IV
Sbjct: 130 APALVSCRRELSLSAGSLQLERKRRDFTSSGSRKLYFDTHALVCLLEDNGFATQQAEIIV 189

Query: 85  SALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKM 144
           SAL  +   ++D +YK+MVT+ QQEIT QQ+M+ +  ++KDM+ILEKSEF+ LRAENEK+
Sbjct: 190 SALVKILEANMDIVYKDMVTKMQQEITFQQVMSQIANVKKDMIILEKSEFSALRAENEKI 249

Query: 145 KIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKS 204
           K+EL Q+KQQ+M E  ++R D KLD NLE+SRV ++++  EK+L+E  TE      Q   
Sbjct: 250 KLELHQLKQQVMDEVIKVRTDTKLDFNLEKSRVKELYSLNEKKLLELRTEIVALHAQQDR 309

Query: 205 IISETSNKIDAEIASLKTLMESNKLETIRYLAASVFTCLAIALGFYRFW 253
            +++T  KI+ E+A LKT++ES+KL+ I+YLA S+FTCL +ALGFYR W
Sbjct: 310 ALTQTDRKIETEVAGLKTMLESHKLDNIKYLAGSIFTCLTVALGFYRLW 358


>gi|38570058 hypothetical protein LOC80129 [Homo sapiens]
          Length = 715

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 44/193 (22%), Positives = 88/193 (45%), Gaps = 15/193 (7%)

Query: 43  GYDRRPVDITPLEQRKLTFDTHALVQDLE-THGFD---KTQAETIVSALTALSNVSLDTI 98
           G+D R   +    ++ +  +++A++++    H      KTQ E + S    +S +     
Sbjct: 453 GFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIA 512

Query: 99  YKEMVTQAQQEITVQQLMAHLDA--IRKDMVILEKSEFANLRAENEKMKIEL---DQVKQ 153
             E   QA+  + V++  AHL    ++K +  L+K E    R  + ++K +L   +++K 
Sbjct: 513 QLEEEKQARTALVVERDNAHLTIRNLQKKVERLQK-ELNTCRDLHTELKAKLADTNELKI 571

Query: 154 QLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKI 213
           + + +T  I      D+N  R ++  M    EK+LM   +E    + + K       N I
Sbjct: 572 KTLEQTKAIE-----DLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMI 626

Query: 214 DAEIASLKTLMES 226
           +   + +KTL +S
Sbjct: 627 EVVTSEMKTLKKS 639


>gi|4557701 keratin 17 [Homo sapiens]
          Length = 432

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 29/122 (23%), Positives = 59/122 (48%), Gaps = 4/122 (3%)

Query: 121 AIRKDMVILEKSEFANLRAENEKMKIELD-QVKQQLMHETSRIRADNKLDINLERSRVTD 179
           A   ++V   KSE + LR   + ++IEL  Q+  +   E +    +N+  + L  S++  
Sbjct: 287 ATNSELVQSGKSEISELRRTMQALEIELQSQLSMKASLEGNLAETENRYCVQL--SQIQG 344

Query: 180 MFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRYLAASV 239
           +    E+QL +   E  +++ + K I+ +   +++ EIA+ + L+E       +Y    V
Sbjct: 345 LIGSVEEQLAQLRCEMEQQNQEYK-ILLDVKTRLEQEIATYRRLLEGEDAHLTQYKKEPV 403

Query: 240 FT 241
            T
Sbjct: 404 TT 405


>gi|38044112 restin isoform b [Homo sapiens]
          Length = 1392

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 1/106 (0%)

Query: 113 QQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINL 172
           QQ M  L       +  E +EFA L+ + EKM+++     + L ++    RA +  ++  
Sbjct: 589 QQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEA 648

Query: 173 ERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKI-DAEI 217
            R+++  +  ++E  L    ++  K + Q    + +T NK+ +AEI
Sbjct: 649 LRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI 694


>gi|4506751 restin isoform a [Homo sapiens]
          Length = 1427

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 26/106 (24%), Positives = 52/106 (49%), Gaps = 1/106 (0%)

Query: 113 QQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINL 172
           QQ M  L       +  E +EFA L+ + EKM+++     + L ++    RA +  ++  
Sbjct: 624 QQAMEELKVSFSKGLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEA 683

Query: 173 ERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKI-DAEI 217
            R+++  +  ++E  L    ++  K + Q    + +T NK+ +AEI
Sbjct: 684 LRAKLMKVIKEKENSLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEI 729


>gi|4757752 angiopoietin-like 1 precursor [Homo sapiens]
          Length = 491

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 32/133 (24%), Positives = 68/133 (51%), Gaps = 16/133 (12%)

Query: 80  AETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRA 139
           A TI   +T +   +L    K+++++ ++EI V QL+  +D    + V L       LR 
Sbjct: 73  ASTIKDMITRMDLENL----KDVLSRQKREIDVLQLVVDVDGNIVNEVKL-------LRK 121

Query: 140 ENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKD 199
           E+  M   + Q+  QL+HE  R R DN L+++   +++ ++ T    ++++  T + + +
Sbjct: 122 ESRNMNSRVTQLYMQLLHEIIRKR-DNSLELSQLENKILNVTT----EMLKMATRYRELE 176

Query: 200 TQTKSIISETSNK 212
            +  S+    +N+
Sbjct: 177 VKYASLTDLVNNQ 189


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 5/70 (7%)

Query: 112  VQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQL-----MHETSRIRADN 166
            V+++    + ++K   IL   + AN+  ENEK+K EL+++K  L     MH  S+ +   
Sbjct: 2141 VEKVQRENEQLKKASGILTSEKMANIEQENEKLKAELEKLKAHLGHQLSMHYESKTKGTE 2200

Query: 167  KLDINLERSR 176
            K+    ER R
Sbjct: 2201 KIIAENERLR 2210



 Score = 28.9 bits (63), Expect = 4.5
 Identities = 41/170 (24%), Positives = 69/170 (40%), Gaps = 33/170 (19%)

Query: 79   QAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLR 138
            Q +++ S L  L  VS D        + Q+EIT +  +   + I+  +    + E   ++
Sbjct: 1633 QDDSLSSLLVKLKKVSQDL-------ERQREIT-ELKVKEFENIKLQLQENHEDEVKKVK 1684

Query: 139  AENEKMKIELDQVKQQLMHETSRIRADNKLDINLERS-------RVTDMFTDQEKQ---- 187
            AE E +K  LDQ +++     S ++A  + +     +       R+      +EKQ    
Sbjct: 1685 AEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKAL 1744

Query: 188  ---LMETTTEFTKKDTQTKSIISETSNK---------IDAEIASLKTLME 225
               L+E   E T      + IIS TS K         +D     LKT +E
Sbjct: 1745 SRALLELRAEMTA--AAEERIISATSQKEAHLNVQQIVDRHTRELKTQVE 1792


>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
          Length = 1710

 Score = 38.5 bits (88), Expect = 0.006
 Identities = 39/176 (22%), Positives = 79/176 (44%), Gaps = 17/176 (9%)

Query: 69   DLETHGFD--------KTQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLD 120
            DL+T  F+        K + + + + L    +  L    K  + Q ++ ++++ +    +
Sbjct: 1387 DLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQILQ-EELLSMKTVQKKCE 1445

Query: 121  AIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDM 180
             ++K+   LE+ E  NLR+  E+  +EL QVKQ       R R +       E+ +  ++
Sbjct: 1446 KLQKNKKKLEQ-EVINLRSHIERNMVELGQVKQYKQEIEERARQE-----IAEKLKEVNL 1499

Query: 181  FTDQEKQLMETTTEFTKKD-TQTKSIISETSNKIDAEIASLKTLMES-NKLETIRY 234
            F   +    E   +F + +    KS +      +++E++ +KT  E  NK E  +Y
Sbjct: 1500 FLQAQAASQENLEQFRENNFASMKSQMELRIKDLESELSKIKTSQEDFNKTELEKY 1555


>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
          Length = 2649

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 40/201 (19%), Positives = 91/201 (45%), Gaps = 19/201 (9%)

Query: 52   TPLEQRKLTFDTHALVQDLETHGFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQEIT 111
            +P+++R++      ++Q+        T   T+++     +  SL  + +E + + ++   
Sbjct: 1056 SPVKRRRMQSSADLIIQEFMDLRTRYTALVTLMTQYIKFAGDSLKRLEEEEIKRCKE--- 1112

Query: 112  VQQLMAHLDAI-RKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIR--ADNKL 168
              +  A+ D + R+   +LE S+     +E E+M  EL + K ++  E  ++R  A+N+L
Sbjct: 1113 TSEHGAYSDLLQRQKATVLENSKLTGKISELERMVAELKKQKSRVEEELPKVREAAENEL 1172

Query: 169  --------DINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASL 220
                    DI+L++ R     ++ ++   E  T   +K+   + +  E   ++  E  + 
Sbjct: 1173 RKQQRNVEDISLQKIRAE---SEAKQYRRELETIVREKEAAEREL--ERVRQLTIEAEAK 1227

Query: 221  KTLMESNKLETIRYLAASVFT 241
            +  +E N L     L  + FT
Sbjct: 1228 RAAVEENLLNFRNQLEENTFT 1248


>gi|169646281 coiled-coil domain containing 14 [Homo sapiens]
          Length = 912

 Score = 38.1 bits (87), Expect = 0.007
 Identities = 43/214 (20%), Positives = 89/214 (41%), Gaps = 14/214 (6%)

Query: 9   LFLSQGRGDRWVSRPRGHFSPALRREFFTTTTKEGYDRRPVDITPLEQRKLTF---DTHA 65
           LF S G+     S+   H SP   +  F  T +E   R  +     E++ L     DT  
Sbjct: 316 LFRSHGKETHLDSQT--HRSPTQSQPAFLATNEEKCAREQIREATSERKDLNIHVRDTKT 373

Query: 66  LVQDLETHGFDKTQAET-----IVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLD 120
           +    +    +KT  +      ++  L AL     D+  + ++T+ +  I+V   ++   
Sbjct: 374 VKDVQKAKNVNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNT 433

Query: 121 AIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERSRVTDM 180
            I+ ++ +  +     LR+EN +++ +L  + QQL  +    +    +D NLE   +  +
Sbjct: 434 DIQVEIALAMQP----LRSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSL 489

Query: 181 FTDQEKQLMETTTEFTKKDTQTKSIISETSNKID 214
               + QL E+        ++ + ++    N+ D
Sbjct: 490 NMSLQNQLEESLKSQELLQSKNEELLKVIENQKD 523


>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
          Length = 1427

 Score = 37.7 bits (86), Expect = 0.010
 Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 14/109 (12%)

Query: 136  NLRAENEKMKIELDQVKQQLMHETSRI----------RADNKLDINLERSRVTD--MFTD 183
            NL+AE+EK  + L +  ++LM E + +          +A  K+D+   +  V    +  D
Sbjct: 1083 NLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKIDLTEAQETVPSRCLHLD 1142

Query: 184  QEKQLME-TTTEFTKKDTQTK-SIISETSNKIDAEIASLKTLMESNKLE 230
             E ++++   T F+ K  Q +   + +   ++  E+ +LK+ ME N LE
Sbjct: 1143 AENEVLQLQQTLFSMKAIQKQCETLQKNKKQLKQEVVNLKSYMERNMLE 1191



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 27/136 (19%), Positives = 61/136 (44%), Gaps = 7/136 (5%)

Query: 49  VDITPLEQRKLTFDTH-ALVQDLETHGFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQ 107
           +++  +E  K  +D   AL Q+ E    +K  A+ + +  +    +  +   K + T+ Q
Sbjct: 687 LELQKIEWEKELYDLRLALKQENE----EKRNADMLYNKDSEQLRIKEEECGKVVETKQQ 742

Query: 108 QEITVQQLMAHLDAIRK--DMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRAD 165
            +  +++L+  L  +R   D+V+ E+++     +E +  +I  DQ+      E    R  
Sbjct: 743 LKWNLRRLVKELRTVRNNLDLVVQERNDAQKQLSEEQDARILQDQILTSKQKELEMARKK 802

Query: 166 NKLDINLERSRVTDMF 181
              +I+    +  D+F
Sbjct: 803 MNSEISHRHQKEKDLF 818


>gi|27894337 keratin 20 [Homo sapiens]
          Length = 424

 Score = 37.0 bits (84), Expect = 0.017
 Identities = 34/180 (18%), Positives = 75/180 (41%), Gaps = 22/180 (12%)

Query: 71  ETHGFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILE 130
           E  G  K    T+   + A   ++L  I  EM  Q  + +  + L    +   +   +L+
Sbjct: 211 EVDGLHKHLGNTVNVEVDAAPGLNLGVIMNEM-RQKYEVMAQKNLQEAKEQFERQTAVLQ 269

Query: 131 KSEFAN-------------LRAENEKMKIELDQ---VKQQLMHETSRIRADNKLDINLER 174
           +    N             LR  ++ ++IEL     +K+ L H       + K   + + 
Sbjct: 270 QQVTVNTEELKGTEVQLTELRRTSQSLEIELQSHLSMKESLEHTLE----ETKARYSSQL 325

Query: 175 SRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNKLETIRY 234
           + +  + +  E QLM+  +   +++ +   I+ +   +++ EIA+ + L+E   ++T  Y
Sbjct: 326 ANLQSLLSSLEAQLMQIRSNMERQNNEYH-ILLDIKTRLEQEIATYRRLLEGEDVKTTEY 384


>gi|151101151 coiled-coil domain containing 2 isoform b [Homo
           sapiens]
          Length = 372

 Score = 37.0 bits (84), Expect = 0.017
 Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 32/199 (16%)

Query: 62  DTHALVQDLETHGFDKTQAETIVSALTALS------NVSLDTIYKEMVTQAQQ----EIT 111
           D + LV  L T+    T+ E +++    L         SLD I+ E   + +Q    E  
Sbjct: 152 DYNMLVDKLNTN----TEMEEVMNDYNMLKAQNDRETQSLDVIFTERQAKEKQIRSVEEE 207

Query: 112 VQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDIN 171
           ++Q     D I K+M    + ++  ++  NEK+  ELD ++QQL    S+      L+  
Sbjct: 208 IEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELDTLQQQL---DSQNMKKESLEAE 264

Query: 172 LERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIIS--ETSNKI-------DAEIASLKT 222
           +  S+V        ++L E  +   +   + KSI S  E   K+       + EIAS++ 
Sbjct: 265 IAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIGSPMEEREKLLKQIKDDNQEIASMER 324

Query: 223 LMESNK------LETIRYL 235
            +   K      +E IR L
Sbjct: 325 QLTDTKEKINQFIEEIRQL 343


>gi|151101140 coiled-coil domain containing 2 isoform a [Homo
           sapiens]
          Length = 600

 Score = 37.0 bits (84), Expect = 0.017
 Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 32/199 (16%)

Query: 62  DTHALVQDLETHGFDKTQAETIVSALTALS------NVSLDTIYKEMVTQAQQ----EIT 111
           D + LV  L T+    T+ E +++    L         SLD I+ E   + +Q    E  
Sbjct: 152 DYNMLVDKLNTN----TEMEEVMNDYNMLKAQNDRETQSLDVIFTERQAKEKQIRSVEEE 207

Query: 112 VQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDIN 171
           ++Q     D I K+M    + ++  ++  NEK+  ELD ++QQL    S+      L+  
Sbjct: 208 IEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELDTLQQQL---DSQNMKKESLEAE 264

Query: 172 LERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIIS--ETSNKI-------DAEIASLKT 222
           +  S+V        ++L E  +   +   + KSI S  E   K+       + EIAS++ 
Sbjct: 265 IAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIGSPMEEREKLLKQIKDDNQEIASMER 324

Query: 223 LMESNK------LETIRYL 235
            +   K      +E IR L
Sbjct: 325 QLTDTKEKINQFIEEIRQL 343


>gi|151105223 coiled-coil domain containing 2 isoform a [Homo
           sapiens]
          Length = 600

 Score = 37.0 bits (84), Expect = 0.017
 Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 32/199 (16%)

Query: 62  DTHALVQDLETHGFDKTQAETIVSALTALS------NVSLDTIYKEMVTQAQQ----EIT 111
           D + LV  L T+    T+ E +++    L         SLD I+ E   + +Q    E  
Sbjct: 152 DYNMLVDKLNTN----TEMEEVMNDYNMLKAQNDRETQSLDVIFTERQAKEKQIRSVEEE 207

Query: 112 VQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDIN 171
           ++Q     D I K+M    + ++  ++  NEK+  ELD ++QQL    S+      L+  
Sbjct: 208 IEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELDTLQQQL---DSQNMKKESLEAE 264

Query: 172 LERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIIS--ETSNKI-------DAEIASLKT 222
           +  S+V        ++L E  +   +   + KSI S  E   K+       + EIAS++ 
Sbjct: 265 IAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIGSPMEEREKLLKQIKDDNQEIASMER 324

Query: 223 LMESNK------LETIRYL 235
            +   K      +E IR L
Sbjct: 325 QLTDTKEKINQFIEEIRQL 343


>gi|151105229 coiled-coil domain containing 2 isoform a [Homo
           sapiens]
          Length = 600

 Score = 37.0 bits (84), Expect = 0.017
 Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 32/199 (16%)

Query: 62  DTHALVQDLETHGFDKTQAETIVSALTALS------NVSLDTIYKEMVTQAQQ----EIT 111
           D + LV  L T+    T+ E +++    L         SLD I+ E   + +Q    E  
Sbjct: 152 DYNMLVDKLNTN----TEMEEVMNDYNMLKAQNDRETQSLDVIFTERQAKEKQIRSVEEE 207

Query: 112 VQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDIN 171
           ++Q     D I K+M    + ++  ++  NEK+  ELD ++QQL    S+      L+  
Sbjct: 208 IEQEKQATDDIIKNMSFENQVKYLEMKTTNEKLLQELDTLQQQL---DSQNMKKESLEAE 264

Query: 172 LERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIIS--ETSNKI-------DAEIASLKT 222
           +  S+V        ++L E  +   +   + KSI S  E   K+       + EIAS++ 
Sbjct: 265 IAHSQVKQEAVLLHEKLYELESHRDQMIAEDKSIGSPMEEREKLLKQIKDDNQEIASMER 324

Query: 223 LMESNK------LETIRYL 235
            +   K      +E IR L
Sbjct: 325 QLTDTKEKINQFIEEIRQL 343


>gi|143770880 laminin, beta 4 [Homo sapiens]
          Length = 1761

 Score = 36.6 bits (83), Expect = 0.022
 Identities = 33/149 (22%), Positives = 68/149 (45%), Gaps = 24/149 (16%)

Query: 79   QAETIVSALTALSNV--SLDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFAN 136
            +A+    A   L N+  +L+ + +  +TQ +   T+ QL A++  I+K++          
Sbjct: 1555 KAKAAEKAANILLNLDKTLNQLQQAQITQGRANSTITQLTANITKIKKNV---------- 1604

Query: 137  LRAENE--KMKIELDQVKQQ--------LMHETSRIRADNKLDINLERSRVTDMFTDQEK 186
            L+AEN+  +MK EL+  KQ+        L+    +   D+ ++  ++           EK
Sbjct: 1605 LQAENQTREMKSELELAKQRSGLEDGLSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEK 1664

Query: 187  QLMETTTEFT--KKDTQTKSIISETSNKI 213
            + +E   ++   ++ T T  +  ET  K+
Sbjct: 1665 EFVELKKQYAILQRKTSTTGLTKETLGKV 1693


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 36.6 bits (83), Expect = 0.022
 Identities = 32/129 (24%), Positives = 60/129 (46%), Gaps = 17/129 (13%)

Query: 106  AQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEK------------MKIELDQVKQ 153
            A+QE T QQL A   +  + + +L+K+    L AE  +            +++ELDQ ++
Sbjct: 1417 AEQERTAQQLRAEKASYAEQLSMLKKAH--GLLAEENRGLGERANLGRQFLEVELDQARE 1474

Query: 154  QLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTK-KDTQTKSIISETSNK 212
            + + E + +RAD   +  L   +     T +E ++M    E  K K  + +    E   K
Sbjct: 1475 KYVQELAAVRAD--AETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQK 1532

Query: 213  IDAEIASLK 221
            + A++  L+
Sbjct: 1533 LTAQVEQLE 1541


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 36.2 bits (82), Expect = 0.028
 Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 14/135 (10%)

Query: 109  EITVQQLMAHLDAIRKDMVILE---------KSEFANLRAENEKMKIELDQVKQQLMHET 159
            E+ ++ L   +D I K    LE         K+E  N   E+++   EL +  +  + + 
Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA 1769

Query: 160  SRIRAD-NKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIA 218
            SR  A  N L   LE +        ++ Q +++  EF ++    KS++S      +A+I 
Sbjct: 1770 SRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ----EAKIR 1825

Query: 219  SLKTLMESNKLETIR 233
             L+T +E  + +  R
Sbjct: 1826 ELETRLEFERTQVKR 1840



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 37/173 (21%), Positives = 71/173 (41%), Gaps = 11/173 (6%)

Query: 57   RKLTFDTHALVQDLETH-GFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQL 115
            + L     A +++LET   F++TQ + + S  + L   +++ + +E   +   E   ++ 
Sbjct: 1814 KSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKE-NMEKLTEERDQRIAAENREKEQ 1872

Query: 116  MAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDINLERS 175
               L    +D    E  E A   AE  + K EL+   + L      ++AD KL       
Sbjct: 1873 NKRLQRQLRDTKE-EMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAF----K 1927

Query: 176  RVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNK 228
            R+ D+    E ++     E          + SE  +++D     +K+ +  NK
Sbjct: 1928 RIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVD----GVKSWLSKNK 1976


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 36.2 bits (82), Expect = 0.028
 Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 14/135 (10%)

Query: 109  EITVQQLMAHLDAIRKDMVILE---------KSEFANLRAENEKMKIELDQVKQQLMHET 159
            E+ ++ L   +D I K    LE         K+E  N   E+++   EL +  +  + + 
Sbjct: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA 1769

Query: 160  SRIRAD-NKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIA 218
            SR  A  N L   LE +        ++ Q +++  EF ++    KS++S      +A+I 
Sbjct: 1770 SRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ----EAKIR 1825

Query: 219  SLKTLMESNKLETIR 233
             L+T +E  + +  R
Sbjct: 1826 ELETRLEFERTQVKR 1840



 Score = 35.8 bits (81), Expect = 0.037
 Identities = 37/180 (20%), Positives = 82/180 (45%), Gaps = 10/180 (5%)

Query: 57   RKLTFDTHALVQDLETH-GFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQQL 115
            + L     A +++LET   F++TQ + + S  + L   +++ + +E   +   E   ++ 
Sbjct: 1814 KSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKE-NMEKLTEERDQRIAAENREKEQ 1872

Query: 116  MAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKLDI----N 171
               L    +D    E  E A   AE  + K EL+   + L      ++AD KL      +
Sbjct: 1873 NKRLQRQLRDTKE-EMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGD 1931

Query: 172  LERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSII---SETSNKIDAEIASLKTLMESNK 228
            L+ +   +M +D+ + L+ +  +   K  + K+ +   S+  ++++  +  +K+ +  NK
Sbjct: 1932 LQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGVKSWLSKNK 1991


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
           sapiens]
          Length = 1133

 Score = 35.8 bits (81), Expect = 0.037
 Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 6/135 (4%)

Query: 100 KEMVTQAQQEITVQQLMAHLDAIRK--DMVILEKSEFANLRAENEKMKIELDQVKQQLMH 157
           +E +     ++ V++L   + A+ K  D     K E  +L+   EK ++   Q+ Q+L  
Sbjct: 405 RETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELES 464

Query: 158 ETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEI 217
              RI+    ++  LE++  T    +   +L   T  F  +       + +T +K+ A  
Sbjct: 465 LKVRIKELEAIESRLEKTEFT--LKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQA-- 520

Query: 218 ASLKTLMESNKLETI 232
           AS +  +E NK+ T+
Sbjct: 521 ASSQLQVEQNKVTTV 535



 Score = 29.3 bits (64), Expect = 3.5
 Identities = 32/132 (24%), Positives = 60/132 (45%), Gaps = 26/132 (19%)

Query: 115 LMAHLDAIRKDMVIL-----------EKSEFANLRAENEKM-----KIELDQVKQQLMHE 158
           +MA ++ +RK ++ +           E+    N R E E +     K+E++++ +++M  
Sbjct: 368 IMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMAL 427

Query: 159 TSRIRADNK-------LDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSN 211
                A NK       L  NLE+ R+T   T Q  Q +E+     K+    +S + +T  
Sbjct: 428 EKLEDAFNKSKQECYSLKCNLEKERMT---TKQLSQELESLKVRIKELEAIESRLEKTEF 484

Query: 212 KIDAEIASLKTL 223
            +  ++  LKTL
Sbjct: 485 TLKEDLTKLKTL 496


>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
           sapiens]
          Length = 893

 Score = 35.8 bits (81), Expect = 0.037
 Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 6/135 (4%)

Query: 100 KEMVTQAQQEITVQQLMAHLDAIRK--DMVILEKSEFANLRAENEKMKIELDQVKQQLMH 157
           +E +     ++ V++L   + A+ K  D     K E  +L+   EK ++   Q+ Q+L  
Sbjct: 165 RETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELES 224

Query: 158 ETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEI 217
              RI+    ++  LE++  T    +   +L   T  F  +       + +T +K+ A  
Sbjct: 225 LKVRIKELEAIESRLEKTEFT--LKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQA-- 280

Query: 218 ASLKTLMESNKLETI 232
           AS +  +E NK+ T+
Sbjct: 281 ASSQLQVEQNKVTTV 295



 Score = 29.3 bits (64), Expect = 3.5
 Identities = 32/132 (24%), Positives = 60/132 (45%), Gaps = 26/132 (19%)

Query: 115 LMAHLDAIRKDMVIL-----------EKSEFANLRAENEKM-----KIELDQVKQQLMHE 158
           +MA ++ +RK ++ +           E+    N R E E +     K+E++++ +++M  
Sbjct: 128 IMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMAL 187

Query: 159 TSRIRADNK-------LDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSN 211
                A NK       L  NLE+ R+T   T Q  Q +E+     K+    +S + +T  
Sbjct: 188 EKLEDAFNKSKQECYSLKCNLEKERMT---TKQLSQELESLKVRIKELEAIESRLEKTEF 244

Query: 212 KIDAEIASLKTL 223
            +  ++  LKTL
Sbjct: 245 TLKEDLTKLKTL 256


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
           sapiens]
          Length = 1135

 Score = 35.8 bits (81), Expect = 0.037
 Identities = 31/135 (22%), Positives = 61/135 (45%), Gaps = 6/135 (4%)

Query: 100 KEMVTQAQQEITVQQLMAHLDAIRK--DMVILEKSEFANLRAENEKMKIELDQVKQQLMH 157
           +E +     ++ V++L   + A+ K  D     K E  +L+   EK ++   Q+ Q+L  
Sbjct: 405 RETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELES 464

Query: 158 ETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEI 217
              RI+    ++  LE++  T    +   +L   T  F  +       + +T +K+ A  
Sbjct: 465 LKVRIKELEAIESRLEKTEFT--LKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQA-- 520

Query: 218 ASLKTLMESNKLETI 232
           AS +  +E NK+ T+
Sbjct: 521 ASSQLQVEQNKVTTV 535



 Score = 29.3 bits (64), Expect = 3.5
 Identities = 32/132 (24%), Positives = 60/132 (45%), Gaps = 26/132 (19%)

Query: 115 LMAHLDAIRKDMVIL-----------EKSEFANLRAENEKM-----KIELDQVKQQLMHE 158
           +MA ++ +RK ++ +           E+    N R E E +     K+E++++ +++M  
Sbjct: 368 IMAEVEELRKRVLDMEGKDEELIKMEEQCRDLNKRLERETLQSKDFKLEVEKLSKRIMAL 427

Query: 159 TSRIRADNK-------LDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSN 211
                A NK       L  NLE+ R+T   T Q  Q +E+     K+    +S + +T  
Sbjct: 428 EKLEDAFNKSKQECYSLKCNLEKERMT---TKQLSQELESLKVRIKELEAIESRLEKTEF 484

Query: 212 KIDAEIASLKTL 223
            +  ++  LKTL
Sbjct: 485 TLKEDLTKLKTL 496


>gi|198442834 coiled-coil domain containing 152 [Homo sapiens]
          Length = 254

 Score = 35.8 bits (81), Expect = 0.037
 Identities = 28/150 (18%), Positives = 68/150 (45%), Gaps = 26/150 (17%)

Query: 108 QEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQL------------ 155
           +E+++++  A L  I K +    + +  NL+ ENE++KI  D +K++L            
Sbjct: 58  KEVSIKEECATLHNIIKGLQQTIEYQ-QNLKGENEQLKISADLIKEKLKSHEQEYKNNIA 116

Query: 156 -------------MHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQT 202
                          E S++  D +  + L   +  ++   +E ++ E   +   ++ + 
Sbjct: 117 KLVSEMKIKEEGYKKEISKLYQDMQRKVELNEEKHKELIEKKEMEISELNAKLRSQEKEK 176

Query: 203 KSIISETSNKIDAEIASLKTLMESNKLETI 232
           ++ I +   + DA++A ++T  +S +  T+
Sbjct: 177 QNEIIKLQLEFDAKLARVQTKSKSYQDSTV 206


>gi|6912236 angiopoietin-like 2 precursor [Homo sapiens]
          Length = 493

 Score = 35.8 bits (81), Expect = 0.037
 Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 9/89 (10%)

Query: 95  LDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQ 154
           L+ +  E++ Q +Q  T+QQL      +  D  I+  SE   LR E+  M   + Q+  Q
Sbjct: 89  LELLNNELLKQKRQIETLQQL------VEVDGGIV--SEVKLLRKESRNMNSRVTQLYMQ 140

Query: 155 LMHETSRIRADNKLDINLERSRVTDMFTD 183
           L+HE  R R DN L+++   +R+ +   D
Sbjct: 141 LLHEIIRKR-DNALELSQLENRILNQTAD 168


>gi|15431310 keratin 14 [Homo sapiens]
          Length = 472

 Score = 35.4 bits (80), Expect = 0.048
 Identities = 26/106 (24%), Positives = 54/106 (50%), Gaps = 4/106 (3%)

Query: 121 AIRKDMVILEKSEFANLRAENEKMKIEL-DQVKQQLMHETSRIRADNKLDINLERSRVTD 179
           A   ++V   KSE + LR   + ++IEL  Q+  +   E S      +  + L  +++ +
Sbjct: 318 ATNSELVQSGKSEISELRRTMQNLEIELQSQLSMKASLENSLEETKGRYCMQL--AQIQE 375

Query: 180 MFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLME 225
           M    E+QL +   E  +++ + K I+ +   +++ EIA+ + L+E
Sbjct: 376 MIGSVEEQLAQLRCEMEQQNQEYK-ILLDVKTRLEQEIATYRRLLE 420


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 35.4 bits (80), Expect = 0.048
 Identities = 29/140 (20%), Positives = 64/140 (45%), Gaps = 6/140 (4%)

Query: 95  LDTIYKEMVTQAQQEITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIE------L 148
           L  ++++ + + +QE+T +      +   +  V LEKS+   L+   EK + E      L
Sbjct: 481 LQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEEL 540

Query: 149 DQVKQQLMHETSRIRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISE 208
           +  K+ ++ E+     D + +    R+R+ ++ +  EK L E   +        ++  ++
Sbjct: 541 ELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNK 600

Query: 209 TSNKIDAEIASLKTLMESNK 228
            + +I   +   KT +ES K
Sbjct: 601 HNKEITVMVEKHKTELESLK 620



 Score = 33.9 bits (76), Expect = 0.14
 Identities = 50/187 (26%), Positives = 81/187 (43%), Gaps = 32/187 (17%)

Query: 67   VQDLETHGFDKTQAETIVSALTALSNVSLDTIYKEMVTQAQQ-----EITVQQLMAHLDA 121
            V  LET+   K Q E++        N  +    K++  QA++     EI +Q+    +  
Sbjct: 1018 VSRLETN--QKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAE 1075

Query: 122  IRKDMVIL--EKSEFAN----LRAENEKMKIEL----DQVKQQLMHETSRIRADNKLDIN 171
            +++ +++   EK E       L+ E  K    L    +Q+KQ+  H  S  + + KL  +
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 1135

Query: 172  LERSRVTDMFTDQEKQLMETT------TEFTKKDTQTKSIISETSNKI---DAEIASLKT 222
            LE+  V     D  K L E T       E      + K  +SE ++K+   D E  SLK+
Sbjct: 1136 LEKLEV-----DLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1190

Query: 223  LME-SNK 228
              E SNK
Sbjct: 1191 SHEKSNK 1197



 Score = 32.7 bits (73), Expect = 0.31
 Identities = 31/127 (24%), Positives = 59/127 (46%), Gaps = 19/127 (14%)

Query: 109  EITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELDQVKQQLMHETSRIRADNKL 168
            EI  Q+L A  D+I    ++ E+ E    + +N++ K+E  + K + M ET +       
Sbjct: 925  EILTQKLSAKEDSIH---ILNEEYE---TKFKNQEKKMEKVKQKAKEMQETLK------- 971

Query: 169  DINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETSNKIDAEIASLKTLMESNK 228
                   ++ D     +K+L  T  E ++K+ Q  + + E +    A I+   + +E+N+
Sbjct: 972  ------KKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQ 1025

Query: 229  LETIRYL 235
             E I  L
Sbjct: 1026 KEQIESL 1032



 Score = 31.2 bits (69), Expect = 0.91
 Identities = 36/152 (23%), Positives = 71/152 (46%), Gaps = 21/152 (13%)

Query: 99  YKEMVT--QAQQEITVQQLMAHLDAIRK--DMVILEKSEFANLRAENEKMKIELDQVK-- 152
           +KE  T   +++E   +QL   L  + K  D+ + EK++      + + +  +L+Q K  
Sbjct: 305 HKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGM 364

Query: 153 -----QQLMHETSRIRADNKLDINLERSRVTDMFT------DQEKQLMETTTEFTKKDTQ 201
                ++ MHET  ++ +   +I   RSR+  M T      +Q+++      E  +K   
Sbjct: 365 VIAETKRQMHETLEMKEE---EIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALS 421

Query: 202 TKSIISETSNKIDAEI-ASLKTLMESNKLETI 232
           T     E   K+ AE+   +KT+ ++++ E I
Sbjct: 422 TAQKTEEARRKLKAEMDEQIKTIEKTSEEERI 453


>gi|157388975 coiled-coil domain containing 99 [Homo sapiens]
          Length = 605

 Score = 35.4 bits (80), Expect = 0.048
 Identities = 31/146 (21%), Positives = 58/146 (39%), Gaps = 18/146 (12%)

Query: 109 EITVQQLMAHLDAIRKDMVILEKSEFANLRAENEKMKIELD-------QVKQQLMHETSR 161
           E   QQ   HL+ + + +      E   L+ + EK+K+ELD       Q+K Q+ H+   
Sbjct: 81  EAIKQQQKMHLEKLEEQLSRSHGQEVNELKTKIEKLKVELDEARLSEKQLKHQVDHQKEL 140

Query: 162 IRADNKLDINLERSRVTDMFTDQEKQLMETTTEFTKKDTQTKSIISETS----------N 211
           +   ++ ++ +   RV +  + +   L    TE     T  K  ++E             
Sbjct: 141 LSCKSE-ELRVMSERVQESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQLELLIT 199

Query: 212 KIDAEIASLKTLMESNKLETIRYLAA 237
            +  ++  LK   E  + E + Y  A
Sbjct: 200 NLMRQVDRLKEEKEEREKEAVSYYNA 225


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 35.0 bits (79), Expect = 0.063
 Identities = 44/175 (25%), Positives = 85/175 (48%), Gaps = 41/175 (23%)

Query: 78   TQAETIVSALTALSNVSLDTIYKEMVTQAQQEITVQ--QLMAHLDAIRKDM--------- 126
            T+ ET+ S L A      + +  +   QA+ E+  +  +L A L A ++++         
Sbjct: 869  TEMETLQSQLMA------EKLQLQEQLQAETELCAEAEELRARLTAKKQELEEICHDLEA 922

Query: 127  -VILEKSEFANLRAENEKMKIELDQVKQQLMHETS--------RIRADNKLDINLERSRV 177
             V  E+    +L+AE +KM+  + ++++QL  E S        ++  + KL   LE  ++
Sbjct: 923  RVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLK-KLEEEQI 981

Query: 178  TDMFTDQ------EKQLMET-----TTEFTKKDTQTKSIISETSNKIDAEIASLK 221
              +  DQ      EK+L+E      TT  T+++ ++KS +++  NK +A I  L+
Sbjct: 982  --ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS-LAKLKNKHEAMITDLE 1033


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.129    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,535,509
Number of Sequences: 37866
Number of extensions: 285058
Number of successful extensions: 1691
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 204
Number of HSP's that attempted gapping in prelim test: 1489
Number of HSP's gapped (non-prelim): 400
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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