Guide to the Human Genome
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Search of human proteins with 20149530

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens]
         (415 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens]           841   0.0  
gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens]           811   0.0  
gi|23199991 casein kinase 1 epsilon [Homo sapiens]                    697   0.0  
gi|4503093 casein kinase 1 epsilon [Homo sapiens]                     697   0.0  
gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]         474   e-134
gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]         459   e-129
gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens]              456   e-128
gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens]        362   e-100
gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens]         362   e-100
gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens]        360   e-99 
gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens]         360   e-99 
gi|153791733 casein kinase 1, gamma 2 [Homo sapiens]                  359   2e-99
gi|98986450 casein kinase 1, gamma 1 [Homo sapiens]                   359   2e-99
gi|58761548 tau tubulin kinase 1 [Homo sapiens]                       180   2e-45
gi|116812624 tau tubulin kinase 2 [Homo sapiens]                      169   4e-42
gi|4507903 vaccinia related kinase 1 [Homo sapiens]                   133   3e-31
gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens]       122   6e-28
gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens]       122   6e-28
gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens]       122   6e-28
gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens]       122   6e-28
gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens]        122   6e-28
gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens]       105   1e-22
gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens]         77   3e-14
gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens]         77   3e-14
gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]           69   1e-11
gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]           69   1e-11
gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]           69   1e-11
gi|38327566 serine/threonine protein kinase 6 [Homo sapiens]           69   1e-11
gi|38327564 serine/threonine protein kinase 6 [Homo sapiens]           69   1e-11
gi|38327562 serine/threonine protein kinase 6 [Homo sapiens]           69   1e-11

>gi|20149530 casein kinase 1, delta isoform 1 [Homo sapiens]
          Length = 415

 Score =  841 bits (2173), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60
           MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
Sbjct: 1   MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60

Query: 61  GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120
           GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
Sbjct: 61  GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120

Query: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
           SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180

Query: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
           SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300
           CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300

Query: 301 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV 360
           ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
Sbjct: 301 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV 360

Query: 361 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR 415
           SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
Sbjct: 361 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR 415


>gi|20544145 casein kinase 1, delta isoform 2 [Homo sapiens]
          Length = 409

 Score =  811 bits (2095), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60
           MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
Sbjct: 1   MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60

Query: 61  GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120
           GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
Sbjct: 61  GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120

Query: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
           SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180

Query: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
           SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300
           CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
Sbjct: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300

Query: 301 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV 360
           ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
Sbjct: 301 ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV 360

Query: 361 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQ 399
           SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQ
Sbjct: 361 SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQ 399


>gi|23199991 casein kinase 1 epsilon [Homo sapiens]
          Length = 416

 Score =  697 bits (1800), Expect = 0.0
 Identities = 345/406 (84%), Positives = 364/406 (89%), Gaps = 7/406 (1%)

Query: 1   MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60
           MELRVGN+YRLGRKIGSGSFGDIYLG +IA+GEEVAIKLECVKTKHPQLHIESK YKMMQ
Sbjct: 1   MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ 60

Query: 61  GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120
           GGVGIP+I+WCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
Sbjct: 61  GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120

Query: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
           SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180

Query: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
           SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300
           CKGYPSEF+TYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGA+R 
Sbjct: 241 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN 300

Query: 301 ADDAERERR--DREERLRHSRNPATRGLP-----STASGRLRGTQEVAPPTPLTPTSHTA 353
            +D +RERR  +REER+   R  ATR LP        + RLR   E    TP +      
Sbjct: 301 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG 360

Query: 354 NTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQ 399
           NTSPR +S ++RERKVSMRLHRGAP N+SSSDLTGRQ+ SR+  SQ
Sbjct: 361 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQ 406


>gi|4503093 casein kinase 1 epsilon [Homo sapiens]
          Length = 416

 Score =  697 bits (1800), Expect = 0.0
 Identities = 345/406 (84%), Positives = 364/406 (89%), Gaps = 7/406 (1%)

Query: 1   MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ 60
           MELRVGN+YRLGRKIGSGSFGDIYLG +IA+GEEVAIKLECVKTKHPQLHIESK YKMMQ
Sbjct: 1   MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ 60

Query: 61  GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120
           GGVGIP+I+WCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
Sbjct: 61  GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH 120

Query: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
           SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
Sbjct: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180

Query: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
           SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
Sbjct: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA 300
           CKGYPSEF+TYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGA+R 
Sbjct: 241 CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN 300

Query: 301 ADDAERERR--DREERLRHSRNPATRGLP-----STASGRLRGTQEVAPPTPLTPTSHTA 353
            +D +RERR  +REER+   R  ATR LP        + RLR   E    TP +      
Sbjct: 301 PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRIQPAG 360

Query: 354 NTSPRPVSGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQ 399
           NTSPR +S ++RERKVSMRLHRGAP N+SSSDLTGRQ+ SR+  SQ
Sbjct: 361 NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRIPASQ 406


>gi|68303572 casein kinase 1, alpha 1 isoform 2 [Homo sapiens]
          Length = 337

 Score =  474 bits (1220), Expect = e-134
 Identities = 225/300 (75%), Positives = 259/300 (86%)

Query: 2   ELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQG 61
           E  VG +Y+L RKIGSGSFGDIYL  +I  GEEVA+KLE  K +HPQL  ESK+YK++QG
Sbjct: 10  EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69

Query: 62  GVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
           GVGIP IRW G E DYNV+VM+LLGPSLEDLFNFCSR+F++KTVL+LADQMISRIEY+H+
Sbjct: 70  GVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHT 129

Query: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181
           KNFIHRD+KPDNFLMG+G+  N +++IDFGLAKKYRD RT QHIPYRE+KNLTGTARYAS
Sbjct: 130 KNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYAS 189

Query: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLC 241
           IN HLGIEQSRRDD+ESLGYVLMYFN  SLPWQGLKAATK+QKYE+ISEKKMSTP+EVLC
Sbjct: 190 INAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLC 249

Query: 242 KGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAA 301
           KG+P+EFA YLN+CR LRF++ PDY YLRQLFR LF      YDY FDW MLK  A++ A
Sbjct: 250 KGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQA 309


>gi|68303575 casein kinase 1, alpha 1 isoform 1 [Homo sapiens]
          Length = 365

 Score =  459 bits (1181), Expect = e-129
 Identities = 225/328 (68%), Positives = 259/328 (78%), Gaps = 28/328 (8%)

Query: 2   ELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQG 61
           E  VG +Y+L RKIGSGSFGDIYL  +I  GEEVA+KLE  K +HPQL  ESK+YK++QG
Sbjct: 10  EFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQG 69

Query: 62  GVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
           GVGIP IRW G E DYNV+VM+LLGPSLEDLFNFCSR+F++KTVL+LADQMISRIEY+H+
Sbjct: 70  GVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHT 129

Query: 122 KNFIHRDVKPDNFLMGLGKKGNL----------------------------VYIIDFGLA 153
           KNFIHRD+KPDNFLMG+G+  N                             +++IDFGLA
Sbjct: 130 KNFIHRDIKPDNFLMGIGRHCNKCLESPVGKRKRSMTVSTSQDPSFSGLNQLFLIDFGLA 189

Query: 154 KKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPW 213
           KKYRD RT QHIPYRE+KNLTGTARYASIN HLGIEQSRRDD+ESLGYVLMYFN  SLPW
Sbjct: 190 KKYRDNRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPW 249

Query: 214 QGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLF 273
           QGLKAATK+QKYE+ISEKKMSTP+EVLCKG+P+EFA YLN+CR LRF++ PDY YLRQLF
Sbjct: 250 QGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF 309

Query: 274 RNLFHRQGFSYDYVFDWNMLKFGASRAA 301
           R LF      YDY FDW MLK  A++ A
Sbjct: 310 RILFRTLNHQYDYTFDWTMLKQKAAQQA 337


>gi|21624639 casein kinase 1, alpha 1-like [Homo sapiens]
          Length = 337

 Score =  456 bits (1172), Expect = e-128
 Identities = 216/300 (72%), Positives = 251/300 (83%)

Query: 2   ELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQG 61
           EL VG +Y+L RKIGSGSFGD+YLG     GEEVA+KLE  K KHPQL  ESK+Y ++QG
Sbjct: 10  ELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEEVAVKLESQKVKHPQLLYESKLYTILQG 69

Query: 62  GVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
           GVGIP + W G E D NV+VM+LLGPSLEDLFNFCSR+F++KTVL+LADQMISRIEY+H+
Sbjct: 70  GVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMISRIEYVHT 129

Query: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181
           KNF+HRD+KPDNFLMG G+  N +++IDFGLAKKYRD RT QHIPYRE+K+L GT RYAS
Sbjct: 130 KNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKHLIGTVRYAS 189

Query: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLC 241
           IN HLGIEQSRRDD+ESLGYV MYFN  SLPWQGLKA TK+QKYE+ISEKKMSTP+EVLC
Sbjct: 190 INAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLKAMTKKQKYEKISEKKMSTPVEVLC 249

Query: 242 KGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRAA 301
           KG+P+EFA YLN+CR LRF++ PDY YLRQLFR LF      YDY FDW MLK  A++ A
Sbjct: 250 KGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTMLKQKAAQQA 309


>gi|113462008 casein kinase 1, gamma 3 isoform 3 [Homo sapiens]
          Length = 415

 Score =  362 bits (929), Expect = e-100
 Identities = 188/373 (50%), Positives = 254/373 (68%), Gaps = 19/373 (5%)

Query: 3   LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGG 62
           L VG  +R+G+KIG G+FG++ LG ++   E VAIKLE +K++ PQLH+E + YK +  G
Sbjct: 37  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96

Query: 63  VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
            GIP + + G  G YN MV+ELLGPSLEDLF+ C R FSLKTVL++A Q+ISR+EY+HSK
Sbjct: 97  DGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSK 156

Query: 123 NFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
           N I+RDVKP+NFL+G    K   +++IIDFGLAK+Y D  T +HIPYRE+K+LTGTARY 
Sbjct: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216

Query: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
           SINTHLG EQSRRDDLE+LG++ MYF  GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--NMLKFGAS 298
           C+ +P E ATYL + R L F +KPDY YLR+LF +LF R+G+ +DY +DW    L     
Sbjct: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVG 335

Query: 299 RAADD----AERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTAN 354
               D    + RE     ++++ S+N       S+ +G      E+    P    S+   
Sbjct: 336 AVQQDPALSSNREAHQHRDKMQQSKNQVV----SSTNG------ELNTDDPTAGRSNAPI 385

Query: 355 TSPRPVSGMERER 367
           T+P  V  M+  +
Sbjct: 386 TAPTEVEVMDETK 398


>gi|73532780 casein kinase 1, gamma 3 isoform 2 [Homo sapiens]
          Length = 423

 Score =  362 bits (928), Expect = e-100
 Identities = 188/370 (50%), Positives = 253/370 (68%), Gaps = 19/370 (5%)

Query: 3   LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGG 62
           L VG  +R+G+KIG G+FG++ LG ++   E VAIKLE +K++ PQLH+E + YK +  G
Sbjct: 37  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96

Query: 63  VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
            GIP + + G  G YN MV+ELLGPSLEDLF+ C R FSLKTVL++A Q+ISR+EY+HSK
Sbjct: 97  DGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSK 156

Query: 123 NFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
           N I+RDVKP+NFL+G    K   +++IIDFGLAK+Y D  T +HIPYRE+K+LTGTARY 
Sbjct: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216

Query: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
           SINTHLG EQSRRDDLE+LG++ MYF  GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--NMLKFGAS 298
           C+ +P E ATYL + R L F +KPDY YLR+LF +LF R+G+ +DY +DW    L     
Sbjct: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVG 335

Query: 299 RAADD----AERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTAN 354
               D    + RE     ++++ S+N       S+ +G      E+    P    S+   
Sbjct: 336 AVQQDPALSSNREAHQHRDKMQQSKNQVV----SSTNG------ELNTDDPTAGRSNAPI 385

Query: 355 TSPRPVSGME 364
           T+P  V  M+
Sbjct: 386 TAPTEVEVMD 395


>gi|113462010 casein kinase 1, gamma 3 isoform 4 [Homo sapiens]
          Length = 455

 Score =  360 bits (925), Expect = e-99
 Identities = 179/326 (54%), Positives = 238/326 (73%), Gaps = 9/326 (2%)

Query: 3   LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGG 62
           L VG  +R+G+KIG G+FG++ LG ++   E VAIKLE +K++ PQLH+E + YK +  G
Sbjct: 37  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96

Query: 63  VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
            GIP + + G  G YN MV+ELLGPSLEDLF+ C R FSLKTVL++A Q+ISR+EY+HSK
Sbjct: 97  DGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSK 156

Query: 123 NFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
           N I+RDVKP+NFL+G    K   +++IIDFGLAK+Y D  T +HIPYRE+K+LTGTARY 
Sbjct: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216

Query: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
           SINTHLG EQSRRDDLE+LG++ MYF  GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--NMLKFGAS 298
           C+ +P E ATYL + R L F +KPDY YLR+LF +LF R+G+ +DY +DW    L     
Sbjct: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVG 335

Query: 299 RAADD----AERERRDREERLRHSRN 320
               D    + RE     ++++ S+N
Sbjct: 336 AVQQDPALSSNREAHQHRDKMQQSKN 361


>gi|73532778 casein kinase 1, gamma 3 isoform 1 [Homo sapiens]
          Length = 447

 Score =  360 bits (925), Expect = e-99
 Identities = 179/326 (54%), Positives = 238/326 (73%), Gaps = 9/326 (2%)

Query: 3   LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGG 62
           L VG  +R+G+KIG G+FG++ LG ++   E VAIKLE +K++ PQLH+E + YK +  G
Sbjct: 37  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGSG 96

Query: 63  VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
            GIP + + G  G YN MV+ELLGPSLEDLF+ C R FSLKTVL++A Q+ISR+EY+HSK
Sbjct: 97  DGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLMIAIQLISRMEYVHSK 156

Query: 123 NFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
           N I+RDVKP+NFL+G    K   +++IIDFGLAK+Y D  T +HIPYRE+K+LTGTARY 
Sbjct: 157 NLIYRDVKPENFLIGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 216

Query: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
           SINTHLG EQSRRDDLE+LG++ MYF  GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 217 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 276

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--NMLKFGAS 298
           C+ +P E ATYL + R L F +KPDY YLR+LF +LF R+G+ +DY +DW    L     
Sbjct: 277 CENFP-EMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTPVG 335

Query: 299 RAADD----AERERRDREERLRHSRN 320
               D    + RE     ++++ S+N
Sbjct: 336 AVQQDPALSSNREAHQHRDKMQQSKN 361


>gi|153791733 casein kinase 1, gamma 2 [Homo sapiens]
          Length = 415

 Score =  359 bits (922), Expect = 2e-99
 Identities = 184/380 (48%), Positives = 257/380 (67%), Gaps = 11/380 (2%)

Query: 3   LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGG 62
           L VG  +R+G+KIG G+FG++ LG ++   E VAIKLE +K++ PQLH+E + YK +   
Sbjct: 40  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSAT 99

Query: 63  VGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSK 122
            G+P + + G  G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q+I+R+EY+H+K
Sbjct: 100 EGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLITRMEYVHTK 159

Query: 123 NFIHRDVKPDNFLMGLG--KKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA 180
           + I+RDVKP+NFL+G    K+ + ++IIDFGLAK+Y D  T +HIPYRE+K+LTGTARY 
Sbjct: 160 SLIYRDVKPENFLVGRPGTKRQHAIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYM 219

Query: 181 SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL 240
           SINTHLG EQSRRDDLE+LG++ MYF  GSLPWQGLKA T +++Y++I + K +TPIEVL
Sbjct: 220 SINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVL 279

Query: 241 CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW--NMLKFGAS 298
           C+ +P E ATYL + R L F +KPDY YLR+LF +LF R GF +DY +DW    L     
Sbjct: 280 CENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGFVFDYEYDWAGKPLPTPIG 339

Query: 299 RAADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVA--PPTPLT-PTSHTANT 355
               D   + + R++   HS+N A     ++ +G L      A     P+T P       
Sbjct: 340 TVHTDLPSQPQLRDKTQPHSKNQAL----NSTNGELNADDPTAGHSNAPITAPAEVEVAD 395

Query: 356 SPRPVSGMERERKVSMRLHR 375
             +     +R ++ S++ H+
Sbjct: 396 ETKCCCFFKRRKRKSLQRHK 415


>gi|98986450 casein kinase 1, gamma 1 [Homo sapiens]
          Length = 422

 Score =  359 bits (922), Expect = 2e-99
 Identities = 169/291 (58%), Positives = 227/291 (78%), Gaps = 3/291 (1%)

Query: 3   LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMM-QG 61
           L VG  +R+G+KIG G+FG++ LG ++   E VAIKLE +K++ PQLH+E + YK +   
Sbjct: 38  LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSA 97

Query: 62  GVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
           G G+P + + G  G YN MV+ELLGPSLEDLF+ C R F+LKTVL++A Q++SR+EY+HS
Sbjct: 98  GEGLPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHS 157

Query: 122 KNFIHRDVKPDNFLMGL--GKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARY 179
           KN I+RDVKP+NFL+G    KK ++++IIDFGLAK+Y D  T +HIPYRE+K+LTGTARY
Sbjct: 158 KNLIYRDVKPENFLIGRQGNKKEHVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARY 217

Query: 180 ASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEV 239
            SINTHLG EQSRRDDLE+LG++ MYF  GSLPWQGLKA T +++Y++I + K +TPIE 
Sbjct: 218 MSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEA 277

Query: 240 LCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290
           LC+ +P E ATYL + R L F +KPDY YLR LF +LF ++G+++DY +DW
Sbjct: 278 LCENFPEEMATYLRYVRRLDFFEKPDYEYLRTLFTDLFEKKGYTFDYAYDW 328


>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
          Length = 1321

 Score =  180 bits (456), Expect = 2e-45
 Identities = 109/292 (37%), Positives = 155/292 (53%), Gaps = 17/292 (5%)

Query: 5   VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64
           V +R+++ +KIG G FG+IY   D+   E VA+K+E  +     L +E  + K +QG   
Sbjct: 30  VKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 89

Query: 65  IPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSR-KFSLKTVLLLADQMISRIEYIHSKN 123
           +     CG    +N +VM+L G +L DL     R  F+L T L L  Q++  IE IHS  
Sbjct: 90  VCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVG 149

Query: 124 FIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
           F+HRD+KP NF MG L       Y++DFGLA++Y +  T    P R      GT RYAS+
Sbjct: 150 FLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNT-TGDVRPPRNVAGFRGTVRYASV 208

Query: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATK----RQKYERISEKKMSTPIE 238
           N H   E  R DDL SL Y+L+ F +G LPW+ +K   +    ++KYE            
Sbjct: 209 NAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEH----------R 258

Query: 239 VLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290
           +L K  PSEF  +L+   SL +  KPDY  +  +F N    +G + +  FDW
Sbjct: 259 MLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDW 310


>gi|116812624 tau tubulin kinase 2 [Homo sapiens]
          Length = 1244

 Score =  169 bits (428), Expect = 4e-42
 Identities = 106/288 (36%), Positives = 149/288 (51%), Gaps = 9/288 (3%)

Query: 5   VGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVG 64
           V  R+++ RKIG G FG+IY   D+   E VA+K+E  +     L +E  + K +QG   
Sbjct: 17  VKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDH 76

Query: 65  IPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSR-KFSLKTVLLLADQMISRIEYIHSKN 123
           +     CG    +N +VM+L G +L DL    SR  F++ T L L  Q++  IE IHS  
Sbjct: 77  VCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVG 136

Query: 124 FIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASI 182
           F+HRD+KP NF MG         Y++DFGLA+++ ++      P R      GT RYASI
Sbjct: 137 FLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVR-PPRAVAGFRGTVRYASI 195

Query: 183 NTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCK 242
           N H   E  R DDL SL Y+L+ F +G LPW+ +K        E++   K      ++ K
Sbjct: 196 NAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIK------DKEQVGSIKERYDHRLMLK 249

Query: 243 GYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 290
             P EF+ +L+   SL +  KPDY  L  +F N     G      FDW
Sbjct: 250 HLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDW 297


>gi|4507903 vaccinia related kinase 1 [Homo sapiens]
          Length = 396

 Score =  133 bits (335), Expect = 3e-31
 Identities = 95/333 (28%), Positives = 154/333 (46%), Gaps = 33/333 (9%)

Query: 9   YRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQ----LHIESKIYK------M 58
           +++G  IG G FG IYL  D+ + E V     CV    P     L  E K Y+       
Sbjct: 37  WKVGLPIGQGGFGCIYLA-DMNSSESVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQ 95

Query: 59  MQGGVGIPTIRWCGAEG------------DYNVMVMELLGPSLEDLFNFCSRKFSLKTVL 106
           +Q  +    +++ G                Y  M+M+  G  L+ ++   +++FS KTVL
Sbjct: 96  IQKWIRTRKLKYLGVPKYWGSGLHDKNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVL 155

Query: 107 LLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIP 166
            L+ +++  +EYIH   ++H D+K  N L+   K  + VY++D+GLA +Y     H+   
Sbjct: 156 QLSLRILDILEYIHEHEYVHGDIKASNLLLNY-KNPDQVYLVDYGLAYRYCPEGVHKEYK 214

Query: 167 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYE 226
               +   GT  + SI+ H G+  SRR DLE LGY ++ +  G LPW+      K  KY 
Sbjct: 215 EDPKRCHDGTIEFTSIDAHNGVAPSRRGDLEILGYCMIQWLTGHLPWED---NLKDPKYV 271

Query: 227 RISEKKMSTPIEVLC------KGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQ 280
           R S+ +    I  L       K  P E A Y+   + L + +KP Y  LR +        
Sbjct: 272 RDSKIRYRENIASLMDKCFPEKNKPGEIAKYMETVKLLDYTEKPLYENLRDILLQGLKAI 331

Query: 281 GFSYDYVFDWNMLKFGASRAADDAERERRDREE 313
           G   D   D ++++ G  +A    ++ +++ EE
Sbjct: 332 GSKDDGKLDLSVVENGGLKAKTITKKRKKEIEE 364


>gi|194440713 vaccinia related kinase 2 isoform 3 [Homo sapiens]
          Length = 396

 Score =  122 bits (306), Expect = 6e-28
 Identities = 95/294 (32%), Positives = 140/294 (47%), Gaps = 34/294 (11%)

Query: 6   GNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVK-TKHPQLHIESKIYKMMQGG-- 62
           GN++ LG+KIGSG FG IYL       E+ A  +  V+  ++  L  E K Y+ +     
Sbjct: 26  GNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDC 85

Query: 63  ------------VGIPTIRWCGAEG----DYNVMVMELLGPSLEDLFNFCSRKFSLKTVL 106
                       +GIP     G        Y  MVME LG  L+ +    +  F   TVL
Sbjct: 86  IKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKKSTVL 144

Query: 107 LLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIP 166
            L  +M+  +EYIH   ++H D+K  N L+G  K  + VY+ D+GL+ +Y     H+   
Sbjct: 145 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY-KNPDQVYLADYGLSYRYCPNGNHKQYQ 203

Query: 167 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPW-QGLK--AATKRQ 223
               K   GT  + S++ H G+  SRR D+E LGY ++ +  G LPW Q LK   A +  
Sbjct: 204 ENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTA 263

Query: 224 KYERISEKKMSTPIEVLCKGYPS-----EFATYLNFCRSLRFDDKPDYSYLRQL 272
           K   + E   S     + K  PS     E A +L    SL +D+KP+Y  L+++
Sbjct: 264 KTNLLDELPQS-----VLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 312


>gi|194440711 vaccinia related kinase 2 isoform 2 [Homo sapiens]
          Length = 485

 Score =  122 bits (306), Expect = 6e-28
 Identities = 95/294 (32%), Positives = 140/294 (47%), Gaps = 34/294 (11%)

Query: 6   GNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVK-TKHPQLHIESKIYKMMQGG-- 62
           GN++ LG+KIGSG FG IYL       E+ A  +  V+  ++  L  E K Y+ +     
Sbjct: 3   GNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDC 62

Query: 63  ------------VGIPTIRWCGAEG----DYNVMVMELLGPSLEDLFNFCSRKFSLKTVL 106
                       +GIP     G        Y  MVME LG  L+ +    +  F   TVL
Sbjct: 63  IKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKKSTVL 121

Query: 107 LLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIP 166
            L  +M+  +EYIH   ++H D+K  N L+G  K  + VY+ D+GL+ +Y     H+   
Sbjct: 122 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY-KNPDQVYLADYGLSYRYCPNGNHKQYQ 180

Query: 167 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPW-QGLK--AATKRQ 223
               K   GT  + S++ H G+  SRR D+E LGY ++ +  G LPW Q LK   A +  
Sbjct: 181 ENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTA 240

Query: 224 KYERISEKKMSTPIEVLCKGYPS-----EFATYLNFCRSLRFDDKPDYSYLRQL 272
           K   + E   S     + K  PS     E A +L    SL +D+KP+Y  L+++
Sbjct: 241 KTNLLDELPQS-----VLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 289


>gi|194440709 vaccinia related kinase 2 isoform 1 [Homo sapiens]
          Length = 508

 Score =  122 bits (306), Expect = 6e-28
 Identities = 95/294 (32%), Positives = 140/294 (47%), Gaps = 34/294 (11%)

Query: 6   GNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVK-TKHPQLHIESKIYKMMQGG-- 62
           GN++ LG+KIGSG FG IYL       E+ A  +  V+  ++  L  E K Y+ +     
Sbjct: 26  GNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDC 85

Query: 63  ------------VGIPTIRWCGAEG----DYNVMVMELLGPSLEDLFNFCSRKFSLKTVL 106
                       +GIP     G        Y  MVME LG  L+ +    +  F   TVL
Sbjct: 86  IKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKKSTVL 144

Query: 107 LLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIP 166
            L  +M+  +EYIH   ++H D+K  N L+G  K  + VY+ D+GL+ +Y     H+   
Sbjct: 145 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY-KNPDQVYLADYGLSYRYCPNGNHKQYQ 203

Query: 167 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPW-QGLK--AATKRQ 223
               K   GT  + S++ H G+  SRR D+E LGY ++ +  G LPW Q LK   A +  
Sbjct: 204 ENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTA 263

Query: 224 KYERISEKKMSTPIEVLCKGYPS-----EFATYLNFCRSLRFDDKPDYSYLRQL 272
           K   + E   S     + K  PS     E A +L    SL +D+KP+Y  L+++
Sbjct: 264 KTNLLDELPQS-----VLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 312


>gi|194440707 vaccinia related kinase 2 isoform 1 [Homo sapiens]
          Length = 508

 Score =  122 bits (306), Expect = 6e-28
 Identities = 95/294 (32%), Positives = 140/294 (47%), Gaps = 34/294 (11%)

Query: 6   GNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVK-TKHPQLHIESKIYKMMQGG-- 62
           GN++ LG+KIGSG FG IYL       E+ A  +  V+  ++  L  E K Y+ +     
Sbjct: 26  GNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDC 85

Query: 63  ------------VGIPTIRWCGAEG----DYNVMVMELLGPSLEDLFNFCSRKFSLKTVL 106
                       +GIP     G        Y  MVME LG  L+ +    +  F   TVL
Sbjct: 86  IKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKKSTVL 144

Query: 107 LLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIP 166
            L  +M+  +EYIH   ++H D+K  N L+G  K  + VY+ D+GL+ +Y     H+   
Sbjct: 145 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY-KNPDQVYLADYGLSYRYCPNGNHKQYQ 203

Query: 167 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPW-QGLK--AATKRQ 223
               K   GT  + S++ H G+  SRR D+E LGY ++ +  G LPW Q LK   A +  
Sbjct: 204 ENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTA 263

Query: 224 KYERISEKKMSTPIEVLCKGYPS-----EFATYLNFCRSLRFDDKPDYSYLRQL 272
           K   + E   S     + K  PS     E A +L    SL +D+KP+Y  L+++
Sbjct: 264 KTNLLDELPQS-----VLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 312


>gi|71164884 vaccinia related kinase 2 isoform 1 [Homo sapiens]
          Length = 508

 Score =  122 bits (306), Expect = 6e-28
 Identities = 95/294 (32%), Positives = 140/294 (47%), Gaps = 34/294 (11%)

Query: 6   GNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVK-TKHPQLHIESKIYKMMQGG-- 62
           GN++ LG+KIGSG FG IYL       E+ A  +  V+  ++  L  E K Y+ +     
Sbjct: 26  GNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVVKVEYQENGPLFSELKFYQRVAKKDC 85

Query: 63  ------------VGIPTIRWCGAEG----DYNVMVMELLGPSLEDLFNFCSRKFSLKTVL 106
                       +GIP     G        Y  MVME LG  L+ +    +  F   TVL
Sbjct: 86  IKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMVMERLGIDLQKISGQ-NGTFKKSTVL 144

Query: 107 LLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIP 166
            L  +M+  +EYIH   ++H D+K  N L+G  K  + VY+ D+GL+ +Y     H+   
Sbjct: 145 QLGIRMLDVLEYIHENEYVHGDIKAANLLLGY-KNPDQVYLADYGLSYRYCPNGNHKQYQ 203

Query: 167 YRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPW-QGLK--AATKRQ 223
               K   GT  + S++ H G+  SRR D+E LGY ++ +  G LPW Q LK   A +  
Sbjct: 204 ENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCMLRWLCGKLPWEQNLKDPVAVQTA 263

Query: 224 KYERISEKKMSTPIEVLCKGYPS-----EFATYLNFCRSLRFDDKPDYSYLRQL 272
           K   + E   S     + K  PS     E A +L    SL +D+KP+Y  L+++
Sbjct: 264 KTNLLDELPQS-----VLKWAPSGSSCCEIAQFLVCAHSLAYDEKPNYQALKKI 312


>gi|209862855 vaccinia related kinase 2 isoform 6 [Homo sapiens]
          Length = 390

 Score =  105 bits (261), Expect = 1e-22
 Identities = 69/201 (34%), Positives = 103/201 (51%), Gaps = 15/201 (7%)

Query: 80  MVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLG 139
           MVME LG  L+ +    +  F   TVL L  +M+  +EYIH   ++H D+K  N L+G  
Sbjct: 1   MVMERLGIDLQKISGQ-NGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGY- 58

Query: 140 KKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESL 199
           K  + VY+ D+GL+ +Y     H+       K   GT  + S++ H G+  SRR D+E L
Sbjct: 59  KNPDQVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEIL 118

Query: 200 GYVLMYFNLGSLPW-QGLK--AATKRQKYERISEKKMSTPIEVLCKGYPS-----EFATY 251
           GY ++ +  G LPW Q LK   A +  K   + E   S     + K  PS     E A +
Sbjct: 119 GYCMLRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQS-----VLKWAPSGSSCCEIAQF 173

Query: 252 LNFCRSLRFDDKPDYSYLRQL 272
           L    SL +D+KP+Y  L+++
Sbjct: 174 LVCAHSLAYDEKPNYQALKKI 194


>gi|71164888 vaccinia related kinase 3 isoform 2 [Homo sapiens]
          Length = 424

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 58/215 (26%), Positives = 101/215 (46%), Gaps = 10/215 (4%)

Query: 63  VGIPTIRWCGAEGD-YNVMVMELLGPSLEDLFNFCSRK-FSLKTVLLLADQMISRIEYIH 120
           + IPT    G   D Y  +V+  LG SL+   +   +   S ++VL +A +++  +E++H
Sbjct: 189 LAIPTCMGFGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLH 248

Query: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLT--GTAR 178
              ++H +V  +N  +    +   V +  +G A +Y    + +H+ Y E       G   
Sbjct: 249 ENEYVHGNVTAENIFVDPEDQSQ-VTLAGYGFAFRY--CPSGKHVAYVEGSRSPHEGDLE 305

Query: 179 YASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIE 238
           + S++ H G   SRR DL+SLGY ++ +  G LPW      T+    ++        P  
Sbjct: 306 FISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDKPGPFV 365

Query: 239 VLCKGY--PSE-FATYLNFCRSLRFDDKPDYSYLR 270
             C  +  PSE    YL    +L +++KP Y+ LR
Sbjct: 366 GPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLR 400


>gi|71164886 vaccinia related kinase 3 isoform 1 [Homo sapiens]
          Length = 474

 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 58/215 (26%), Positives = 101/215 (46%), Gaps = 10/215 (4%)

Query: 63  VGIPTIRWCGAEGD-YNVMVMELLGPSLEDLFNFCSRK-FSLKTVLLLADQMISRIEYIH 120
           + IPT    G   D Y  +V+  LG SL+   +   +   S ++VL +A +++  +E++H
Sbjct: 239 LAIPTCMGFGVHQDKYRFLVLPSLGRSLQSALDVSPKHVLSERSVLQVACRLLDALEFLH 298

Query: 121 SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLT--GTAR 178
              ++H +V  +N  +    +   V +  +G A +Y    + +H+ Y E       G   
Sbjct: 299 ENEYVHGNVTAENIFVDPEDQSQ-VTLAGYGFAFRY--CPSGKHVAYVEGSRSPHEGDLE 355

Query: 179 YASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIE 238
           + S++ H G   SRR DL+SLGY ++ +  G LPW      T+    ++        P  
Sbjct: 356 FISMDLHKGCGPSRRSDLQSLGYCMLKWLYGFLPWTNCLPNTEDIMKQKQKFVDKPGPFV 415

Query: 239 VLCKGY--PSE-FATYLNFCRSLRFDDKPDYSYLR 270
             C  +  PSE    YL    +L +++KP Y+ LR
Sbjct: 416 GPCGHWIRPSETLQKYLKVVMALTYEEKPPYAMLR 450


>gi|38327572 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 25/235 (10%)

Query: 9   YRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMM--QGGVGIP 66
           + +GR +G G FG++YL  +  +   +A+K+   K +  +  +E ++ + +  Q  +  P
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKV-LFKAQLEKAGVEHQLRREVEIQSHLRHP 191

Query: 67  TI-RWCGAEGD----YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
            I R  G   D    Y ++    LG    +L      KF  +       ++ + + Y HS
Sbjct: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALSYCHS 249

Query: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181
           K  IHRD+KP+N L  LG  G L  I DFG +          H P      L GT  Y  
Sbjct: 250 KRVIHRDIKPENLL--LGSAGEL-KIADFGWS---------VHAPSSRRTTLCGTLDYLP 297

Query: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTP 236
                G     + DL SLG +   F +G  P++   A T ++ Y+RIS  + + P
Sbjct: 298 PEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349


>gi|38327570 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 25/235 (10%)

Query: 9   YRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMM--QGGVGIP 66
           + +GR +G G FG++YL  +  +   +A+K+   K +  +  +E ++ + +  Q  +  P
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKV-LFKAQLEKAGVEHQLRREVEIQSHLRHP 191

Query: 67  TI-RWCGAEGD----YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
            I R  G   D    Y ++    LG    +L      KF  +       ++ + + Y HS
Sbjct: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALSYCHS 249

Query: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181
           K  IHRD+KP+N L  LG  G L  I DFG +          H P      L GT  Y  
Sbjct: 250 KRVIHRDIKPENLL--LGSAGEL-KIADFGWS---------VHAPSSRRTTLCGTLDYLP 297

Query: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTP 236
                G     + DL SLG +   F +G  P++   A T ++ Y+RIS  + + P
Sbjct: 298 PEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349


>gi|38327568 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 25/235 (10%)

Query: 9   YRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMM--QGGVGIP 66
           + +GR +G G FG++YL  +  +   +A+K+   K +  +  +E ++ + +  Q  +  P
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKV-LFKAQLEKAGVEHQLRREVEIQSHLRHP 191

Query: 67  TI-RWCGAEGD----YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
            I R  G   D    Y ++    LG    +L      KF  +       ++ + + Y HS
Sbjct: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALSYCHS 249

Query: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181
           K  IHRD+KP+N L  LG  G L  I DFG +          H P      L GT  Y  
Sbjct: 250 KRVIHRDIKPENLL--LGSAGEL-KIADFGWS---------VHAPSSRRTTLCGTLDYLP 297

Query: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTP 236
                G     + DL SLG +   F +G  P++   A T ++ Y+RIS  + + P
Sbjct: 298 PEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349


>gi|38327566 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 25/235 (10%)

Query: 9   YRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMM--QGGVGIP 66
           + +GR +G G FG++YL  +  +   +A+K+   K +  +  +E ++ + +  Q  +  P
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKV-LFKAQLEKAGVEHQLRREVEIQSHLRHP 191

Query: 67  TI-RWCGAEGD----YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
            I R  G   D    Y ++    LG    +L      KF  +       ++ + + Y HS
Sbjct: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALSYCHS 249

Query: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181
           K  IHRD+KP+N L  LG  G L  I DFG +          H P      L GT  Y  
Sbjct: 250 KRVIHRDIKPENLL--LGSAGEL-KIADFGWS---------VHAPSSRRTTLCGTLDYLP 297

Query: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTP 236
                G     + DL SLG +   F +G  P++   A T ++ Y+RIS  + + P
Sbjct: 298 PEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349


>gi|38327564 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 25/235 (10%)

Query: 9   YRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMM--QGGVGIP 66
           + +GR +G G FG++YL  +  +   +A+K+   K +  +  +E ++ + +  Q  +  P
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKV-LFKAQLEKAGVEHQLRREVEIQSHLRHP 191

Query: 67  TI-RWCGAEGD----YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
            I R  G   D    Y ++    LG    +L      KF  +       ++ + + Y HS
Sbjct: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALSYCHS 249

Query: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181
           K  IHRD+KP+N L  LG  G L  I DFG +          H P      L GT  Y  
Sbjct: 250 KRVIHRDIKPENLL--LGSAGEL-KIADFGWS---------VHAPSSRRTTLCGTLDYLP 297

Query: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTP 236
                G     + DL SLG +   F +G  P++   A T ++ Y+RIS  + + P
Sbjct: 298 PEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349


>gi|38327562 serine/threonine protein kinase 6 [Homo sapiens]
          Length = 403

 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 66/235 (28%), Positives = 105/235 (44%), Gaps = 25/235 (10%)

Query: 9   YRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMM--QGGVGIP 66
           + +GR +G G FG++YL  +  +   +A+K+   K +  +  +E ++ + +  Q  +  P
Sbjct: 133 FEIGRPLGKGKFGNVYLAREKQSKFILALKV-LFKAQLEKAGVEHQLRREVEIQSHLRHP 191

Query: 67  TI-RWCGAEGD----YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHS 121
            I R  G   D    Y ++    LG    +L      KF  +       ++ + + Y HS
Sbjct: 192 NILRLYGYFHDATRVYLILEYAPLGTVYRELQKLS--KFDEQRTATYITELANALSYCHS 249

Query: 122 KNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYAS 181
           K  IHRD+KP+N L  LG  G L  I DFG +          H P      L GT  Y  
Sbjct: 250 KRVIHRDIKPENLL--LGSAGEL-KIADFGWS---------VHAPSSRRTTLCGTLDYLP 297

Query: 182 INTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTP 236
                G     + DL SLG +   F +G  P++   A T ++ Y+RIS  + + P
Sbjct: 298 PEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFE---ANTYQETYKRISRVEFTFP 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,645,652
Number of Sequences: 37866
Number of extensions: 739092
Number of successful extensions: 4524
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 484
Number of HSP's successfully gapped in prelim test: 264
Number of HSP's that attempted gapping in prelim test: 3317
Number of HSP's gapped (non-prelim): 986
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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