Guide to the Human Genome
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Search of human proteins with 20127624

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5
[Homo sapiens]
         (747 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5 [Hom...  1529   0.0  
gi|132566532 dual oxidase 2 precursor [Homo sapiens]                  248   1e-65
gi|20149640 dual oxidase 1 precursor [Homo sapiens]                   231   2e-60
gi|28872751 dual oxidase 1 precursor [Homo sapiens]                   231   2e-60
gi|148536873 NADPH oxidase 1 isoform long [Homo sapiens]              228   2e-59
gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens]           214   2e-55
gi|11136626 NADPH oxidase 3 [Homo sapiens]                            209   1e-53
gi|7669510 NADPH oxidase 1 isoform long variant [Homo sapiens]        176   5e-44
gi|219842348 NADPH oxidase 4 isoform c [Homo sapiens]                 119   1e-26
gi|8393843 NADPH oxidase 4 isoform a [Homo sapiens]                   119   1e-26
gi|219842346 NADPH oxidase 4 isoform b [Homo sapiens]                  69   2e-11
gi|40254415 guanylate cyclase activator 1A (retina) [Homo sapiens]     65   2e-10
gi|4506025 protein phosphatase 3, regulatory subunit B, alpha is...    55   3e-07
gi|98985795 neurocalcin delta [Homo sapiens]                           50   1e-05
gi|98985793 neurocalcin delta [Homo sapiens]                           50   1e-05
gi|98985791 neurocalcin delta [Homo sapiens]                           50   1e-05
gi|98985789 neurocalcin delta [Homo sapiens]                           50   1e-05
gi|98985787 neurocalcin delta [Homo sapiens]                           50   1e-05
gi|98985785 neurocalcin delta [Homo sapiens]                           50   1e-05
gi|98985783 neurocalcin delta [Homo sapiens]                           50   1e-05
gi|98985778 neurocalcin delta [Homo sapiens]                           50   1e-05
gi|19913443 hippocalcin-like 1 [Homo sapiens]                          48   3e-05
gi|19913441 hippocalcin-like 1 [Homo sapiens]                          48   3e-05
gi|153945858 guanylate cyclase activator 1B (retina) [Homo sapiens]    47   5e-05
gi|13375787 EF-hand calcium binding domain 1 isoform a [Homo sap...    47   6e-05
gi|19913446 hippocalcin [Homo sapiens]                                 46   1e-04
gi|33946291 lysophosphatidylcholine acyltransferase 1 [Homo sapi...    45   2e-04
gi|78190495 Kv channel interacting protein 3 isoform 2 [Homo sap...    44   4e-04
gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo sapi...    44   4e-04
gi|22212896 protein phosphatase 3 regulatory subunit B, beta iso...    44   5e-04

>gi|20127624 NADPH oxidase, EF-hand calcium binding domain 5 [Homo
           sapiens]
          Length = 747

 Score = 1530 bits (3960), Expect = 0.0
 Identities = 747/747 (100%), Positives = 747/747 (100%)

Query: 1   MSAEEDARWLRWVTQQFKTIAGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTIT 60
           MSAEEDARWLRWVTQQFKTIAGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTIT
Sbjct: 1   MSAEEDARWLRWVTQQFKTIAGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTIT 60

Query: 61  LQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGS 120
           LQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGS
Sbjct: 61  LQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGS 120

Query: 121 GSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFP 180
           GSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFP
Sbjct: 121 GSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFP 180

Query: 181 GVMENLTISAAHWLTAPAPRPRPRRPRQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAAS 240
           GVMENLTISAAHWLTAPAPRPRPRRPRQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAAS
Sbjct: 181 GVMENLTISAAHWLTAPAPRPRPRRPRQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAAS 240

Query: 241 AHRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMG 300
           AHRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMG
Sbjct: 241 AHRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMG 300

Query: 301 YVVVGLSLVHTVAHTVNFVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLL 360
           YVVVGLSLVHTVAHTVNFVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLL
Sbjct: 301 YVVVGLSLVHTVAHTVNFVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLL 360

Query: 361 LLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHGPNFWKWLLVPGILFFLEKAIGL 420
           LLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHGPNFWKWLLVPGILFFLEKAIGL
Sbjct: 361 LLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHGPNFWKWLLVPGILFFLEKAIGL 420

Query: 421 AVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAP 480
           AVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAP
Sbjct: 421 AVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAP 480

Query: 481 EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKH 540
           EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKH
Sbjct: 481 EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKH 540

Query: 541 KFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQ 600
           KFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQ
Sbjct: 541 KFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQ 600

Query: 601 HSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTS 660
           HSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTS
Sbjct: 601 HSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTS 660

Query: 661 ALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKGKVQVF 720
           ALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKGKVQVF
Sbjct: 661 ALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKGKVQVF 720

Query: 721 FCGSPALAKVLKGHCEKFGFRFFQENF 747
           FCGSPALAKVLKGHCEKFGFRFFQENF
Sbjct: 721 FCGSPALAKVLKGHCEKFGFRFFQENF 747


>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
          Length = 1548

 Score =  248 bits (633), Expect = 1e-65
 Identities = 213/807 (26%), Positives = 352/807 (43%), Gaps = 176/807 (21%)

Query: 26   EISLQEFKAALHVK-ESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLF 84
            E+S  EF  +L +K +  F E  F+L D D +G ++ +E  + L + + GSP DK + +F
Sbjct: 805  ELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEDKSRLMF 864

Query: 85   QVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLP 144
             +YD+D     G  +  E+          S +   +  +   +L  V++S  RES     
Sbjct: 865  TMYDLD---ENGFLSKDEFFT-----MMRSFIEISNNCLSKAQLAEVVESMFRESGF--- 913

Query: 145  DEKLDQLTLALFESADADGNGAITFEEL------------RDELQ-----------RFPG 181
             +  ++LT   F     D +  + F +L            RD  +           R PG
Sbjct: 914  -QDKEELTWEDFHFMLRDHDSELRFTQLCVKGGGGGGNGIRDIFKQNISCRVSFITRTPG 972

Query: 182  VMENLTISAAHWLTAPAPR-------------------PRPR----------------RP 206
                   S    L  PAP                    P PR                + 
Sbjct: 973  ER-----SHPQGLGPPAPEAPELGGPGLKKRFGKKAAVPTPRLYTEALQEKMQRGFLAQK 1027

Query: 207  RQLTRAYWHNHRSQLFCLATYAGLHVLLFGLAA------SAHRDLGASVMV----AKGCG 256
             Q  + +  N+R  + C+A ++ + V +F   A      S   D+  + +V    ++G  
Sbjct: 1028 LQQYKRFVENYRRHIVCVAIFSAICVGVFADRAYYYGFASPPSDIAQTTLVGIILSRGTA 1087

Query: 257  QCLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMGYVVVGLSLVHTVAHTV 316
              ++F  S+I + M R  +T+LR T+L + +P D  + FH+ +    V L+++H+  H V
Sbjct: 1088 ASVSFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRWIAMAAVVLAILHSAGHAV 1147

Query: 317  NFVLQAQAEAS-----------------PFQFWELLLTTRPGIGWVHGSASPTGVALLLL 359
            N  + + +  S                 P +F+     T PG+         TGV LLL+
Sbjct: 1148 NVYIFSVSPLSLLACIFPNVFVNDGSKLPQKFYWWFFQTVPGM---------TGVLLLLV 1198

Query: 360  LLLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG-------PNFWKWLLVPGILF 412
            L +M++ +S   RR   F  F+ TH  Y+L++ LLI HG       P F  + LVP I++
Sbjct: 1199 LAIMYVFASHHFRRRS-FRGFWLTHHLYILLYALLIIHGSYALIQLPTFHIYFLVPAIIY 1257

Query: 413  FLEKAIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWH 472
              +K + L+  +   + +++  LLPS VT+L  +RP  F Y+ G ++ +    +   E+H
Sbjct: 1258 GGDKLVSLS-RKKVEISVVKAELLPSGVTYLQFQRPQGFEYKSGQWVRIACLALGTTEYH 1316

Query: 473  PFTISSAPEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKG 532
            PFT++SAP + DT+ LHIR+ G WT RL E +  S P G G                   
Sbjct: 1317 PFTLTSAPHE-DTLSLHIRAVGPWTTRLREIY--SSPKGNGCAGYP-------------- 1359

Query: 533  SEILLEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKR 592
                         K Y+DGP+G   +     E +VL+G GIG+TPFASIL+ ++++    
Sbjct: 1360 -------------KLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK---- 1402

Query: 593  KHTCPSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFL 652
                          +   M   K+ FIW+ R QR FEW   ++      + EE  +   +
Sbjct: 1403 ------------SSLGSQMLCKKIYFIWVTRTQRQFEWLADII-----QEVEENDHQDLV 1445

Query: 653  ELHMYMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVF---QKV 709
             +H+Y+T    K D++   L +          +   TGL++ T  GRP +   F   Q+V
Sbjct: 1446 SVHIYVTQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEV 1505

Query: 710  AAEKKGKVQVFFCGSPALAKVLKGHCE 736
              + + K+ VF CG P + K ++  C+
Sbjct: 1506 HPQVR-KIGVFSCGPPGMTKNVEKACQ 1531


>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score =  231 bits (588), Expect = 2e-60
 Identities = 167/563 (29%), Positives = 270/563 (47%), Gaps = 94/563 (16%)

Query: 208  QLTRAYWHNHRSQLFCLATYAGLHVLLF-----GLAASAHRD-----LGASVMVAKGCGQ 257
            Q  + +  N+R  + C+A +  +   LF       A +AH           +++++G   
Sbjct: 1032 QQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAA 1091

Query: 258  CLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMGYVVVGLSLVHTVAHTVN 317
             ++F  S+I + M R  +T+LR T+L + +P D  + FH+L+    + L+++H+V H VN
Sbjct: 1092 SISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVN 1151

Query: 318  FVLQAQAEASPFQFWELLLTTRPGIGWVHGSASP--------------TGVALLLLLLLM 363
              L      SP      L    PG+    GS  P              TGV LLL+L +M
Sbjct: 1152 VYL---FSISPLSVLSCLF---PGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIM 1205

Query: 364  FICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG-------PNFWKWLLVPGILFFLEK 416
            ++ +S   RR   F  F+ TH  Y+L+++LLI HG       P F  + LVP I++  +K
Sbjct: 1206 YVFASHHFRRRS-FRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDK 1264

Query: 417  AIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTI 476
             + L+  +   + +++  LLPS VTHL  +RP  F Y+ G ++ +    +   E+HPFT+
Sbjct: 1265 LVSLS-RKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTL 1323

Query: 477  SSAPEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEIL 536
            +SAP + DT+ LHIR+ G WT RL E + A  P G    R                    
Sbjct: 1324 TSAPHE-DTLSLHIRAAGPWTTRLREIYSA--PTGDRCARYP------------------ 1362

Query: 537  LEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTC 596
                     K Y+DGP+G   +     E +VL+G GIG+TPFASIL+ ++++      + 
Sbjct: 1363 ---------KLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK------SS 1407

Query: 597  PSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHM 656
             SCQ          +   K+ FIW+ R QR FEW   ++      + EE  +   + +H+
Sbjct: 1408 VSCQ----------VFCKKIYFIWVTRTQRQFEWLADIIR-----EVEENDHQDLVSVHI 1452

Query: 657  YMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVF---QKVAAEK 713
            Y+T    K D++   L +          +   TGL++ T  GRP +   F   Q+V  + 
Sbjct: 1453 YITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQV 1512

Query: 714  KGKVQVFFCGSPALAKVLKGHCE 736
            + K+ VF CG P + K ++  C+
Sbjct: 1513 R-KIGVFSCGPPGMTKNVEKACQ 1534



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 16/186 (8%)

Query: 26  EISLQEFKAALHVK-ESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLF 84
           E+S  EF  +L +K +  F E  F+L D D +G ++ +E  + L + + GSP +K + +F
Sbjct: 801 ELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMF 860

Query: 85  QVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLP 144
           ++YD D     G  +  E+          S +   +  +   +L  V++S  RES     
Sbjct: 861 RMYDFD---GNGLISKDEF-----IRMLRSFIEISNNCLSKAQLAEVVESMFRESGF--- 909

Query: 145 DEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMENLTISAAHW---LTAPAPRP 201
            +  ++LT   F     D N  + F +L  +    P V+++L   A++    +  P+PR 
Sbjct: 910 -QDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRV 968

Query: 202 RPRRPR 207
             R  R
Sbjct: 969 SARCSR 974


>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
          Length = 1551

 Score =  231 bits (588), Expect = 2e-60
 Identities = 167/563 (29%), Positives = 270/563 (47%), Gaps = 94/563 (16%)

Query: 208  QLTRAYWHNHRSQLFCLATYAGLHVLLF-----GLAASAHRD-----LGASVMVAKGCGQ 257
            Q  + +  N+R  + C+A +  +   LF       A +AH           +++++G   
Sbjct: 1032 QQFKRFIENYRRHIGCVAVFYAIAGGLFLERAYYYAFAAHHTGITDTTRVGIILSRGTAA 1091

Query: 258  CLNFDCSFIAVLMLRRCLTWLRATWLAQVLPLDQNIQFHQLMGYVVVGLSLVHTVAHTVN 317
             ++F  S+I + M R  +T+LR T+L + +P D  + FH+L+    + L+++H+V H VN
Sbjct: 1092 SISFMFSYILLTMCRNLITFLRETFLNRYVPFDAAVDFHRLIASTAIVLTVLHSVGHVVN 1151

Query: 318  FVLQAQAEASPFQFWELLLTTRPGIGWVHGSASP--------------TGVALLLLLLLM 363
              L      SP      L    PG+    GS  P              TGV LLL+L +M
Sbjct: 1152 VYL---FSISPLSVLSCLF---PGLFHDDGSELPQKYYWWFFQTVPGLTGVVLLLILAIM 1205

Query: 364  FICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG-------PNFWKWLLVPGILFFLEK 416
            ++ +S   RR   F  F+ TH  Y+L+++LLI HG       P F  + LVP I++  +K
Sbjct: 1206 YVFASHHFRRRS-FRGFWLTHHLYILLYVLLIIHGSFALIQLPRFHIFFLVPAIIYGGDK 1264

Query: 417  AIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTI 476
             + L+  +   + +++  LLPS VTHL  +RP  F Y+ G ++ +    +   E+HPFT+
Sbjct: 1265 LVSLS-RKKVEISVVKAELLPSGVTHLRFQRPQGFEYKSGQWVRIACLALGTTEYHPFTL 1323

Query: 477  SSAPEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEIL 536
            +SAP + DT+ LHIR+ G WT RL E + A  P G    R                    
Sbjct: 1324 TSAPHE-DTLSLHIRAAGPWTTRLREIYSA--PTGDRCARYP------------------ 1362

Query: 537  LEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTC 596
                     K Y+DGP+G   +     E +VL+G GIG+TPFASIL+ ++++      + 
Sbjct: 1363 ---------KLYLDGPFGEGHQEWHKFEVSVLVGGGIGVTPFASILKDLVFK------SS 1407

Query: 597  PSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHM 656
             SCQ          +   K+ FIW+ R QR FEW   ++      + EE  +   + +H+
Sbjct: 1408 VSCQ----------VFCKKIYFIWVTRTQRQFEWLADIIR-----EVEENDHQDLVSVHI 1452

Query: 657  YMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVF---QKVAAEK 713
            Y+T    K D++   L +          +   TGL++ T  GRP +   F   Q+V  + 
Sbjct: 1453 YITQLAEKFDLRTTMLYICERHFQKVLNRSLFTGLRSITHFGRPPFEPFFNSLQEVHPQV 1512

Query: 714  KGKVQVFFCGSPALAKVLKGHCE 736
            + K+ VF CG P + K ++  C+
Sbjct: 1513 R-KIGVFSCGPPGMTKNVEKACQ 1534



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 48/186 (25%), Positives = 86/186 (46%), Gaps = 16/186 (8%)

Query: 26  EISLQEFKAALHVK-ESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLF 84
           E+S  EF  +L +K +  F E  F+L D D +G ++ +E  + L + + GSP +K + +F
Sbjct: 801 ELSRAEFAESLGLKPQDMFVESMFSLADKDGNGYLSFREFLDILVVFMKGSPEEKSRLMF 860

Query: 85  QVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLP 144
           ++YD D     G  +  E+          S +   +  +   +L  V++S  RES     
Sbjct: 861 RMYDFD---GNGLISKDEF-----IRMLRSFIEISNNCLSKAQLAEVVESMFRESGF--- 909

Query: 145 DEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMENLTISAAHW---LTAPAPRP 201
            +  ++LT   F     D N  + F +L  +    P V+++L   A++    +  P+PR 
Sbjct: 910 -QDKEELTWEDFHFMLRDHNSELRFTQLCVKGVEVPEVIKDLCRRASYISQDMICPSPRV 968

Query: 202 RPRRPR 207
             R  R
Sbjct: 969 SARCSR 974


>gi|148536873 NADPH oxidase 1 isoform long [Homo sapiens]
          Length = 564

 Score =  228 bits (580), Expect = 2e-59
 Identities = 182/620 (29%), Positives = 279/620 (45%), Gaps = 150/620 (24%)

Query: 216 NHRSQLFCLATYAGLHVLLFGLAASAHRD----------LGASVMVAKGCGQCLNFDCSF 265
           NH   +  L  + GL+V LF  A   +            LG+++  A+    CLNF+ + 
Sbjct: 7   NHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTL 66

Query: 266 IAVLMLRRCLTWLRAT--WLAQVL--PLDQNIQFHQLMGYVVVGLSLVHTVAHTVNFVLQ 321
           I + + R  L++LR T  + ++ L   LD N+ FH+L+ Y++   + +H +AH  NF   
Sbjct: 67  ILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCY 126

Query: 322 AQAEASPFQFWELLLTT-----RPGIGWVH---------------GSASPTGVALLLLLL 361
           +++  +       +L++     + G  W++                 A  TGV + + L+
Sbjct: 127 SRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALI 186

Query: 362 LMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG----------------------- 398
           LM   ++  IRRS +FEVF++TH  ++   L L  HG                       
Sbjct: 187 LMVTSATEFIRRS-YFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAE 245

Query: 399 ---------------------PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLP 437
                                P  WKW+L P IL+  E+ +    S+   V I +V + P
Sbjct: 246 SFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVV-ITKVVMHP 304

Query: 438 SKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAPEQKDTIWLHIRSQGQWT 497
           SKV  L + +  F     G Y+++N P+I+  EWHPFT++SAPE+ D   +HIR+ G WT
Sbjct: 305 SKVLELQMNKRGF-SMEVGQYIFVNCPSISLLEWHPFTLTSAPEE-DFFSIHIRAAGDWT 362

Query: 498 NRLYESFKAS-DPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTP 556
             L  +F+    P+ R                                    +DGP+GT 
Sbjct: 363 ENLIRAFEQQYSPIPR----------------------------------IEVDGPFGTA 388

Query: 557 TRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKV 616
           +  +F  E AVL+GAGIG+TPFASIL+SI Y+ Q   H               N+K  K+
Sbjct: 389 SEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADH---------------NLKTKKI 433

Query: 617 DFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMAL 676
            F WI R+  +F WF +LLT LE +  E  + G FL   +++T      D   +G   AL
Sbjct: 434 YFYWICRETGAFSWFNNLLTSLEQEMEELGKVG-FLNYRLFLTGW----DSNIVG-HAAL 487

Query: 677 DLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVA-AEKKGKVQVFFCGSPALAKVLKGHC 735
           +     +  D +TGL+ +T  GRP W   F  +A +  K  V VF CG   LAK L+  C
Sbjct: 488 NF---DKATDIVTGLKQKTSFGRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCC 544

Query: 736 EKFG--------FRFFQENF 747
            ++         F F +ENF
Sbjct: 545 HRYSSLDPRKVQFYFNKENF 564


>gi|6996021 cytochrome b-245 beta polypeptide [Homo sapiens]
          Length = 570

 Score =  214 bits (546), Expect = 2e-55
 Identities = 166/595 (27%), Positives = 270/595 (45%), Gaps = 134/595 (22%)

Query: 216 NHRSQLFCLATYAGLHVLLFGLAASAH----------RDLGASVMVAKGCGQCLNFDCSF 265
           N    +F +  + GL+V LF      +          + LG+++ +A+    CLNF+C  
Sbjct: 7   NEGLSIFVILVWLGLNVFLFVWYYRVYDIPPKFFYTRKLLGSALALARAPAACLNFNCML 66

Query: 266 IAVLMLRRCLTWLRATWLAQVL----PLDQNIQFHQLMGYVVVGLSLVHTVAHTVNFVLQ 321
           I + + R  L++LR +           LD+N+ FH+++ +++   S +HT+AH  N    
Sbjct: 67  ILLPVCRNLLSFLRGSSACCSTRVRRQLDRNLTFHKMVAWMIALHSAIHTIAHLFNVEWC 126

Query: 322 AQAEASPFQFWELLLT-------------TRPGIGWVHGS--------ASPTGVALLLLL 360
             A  +    + + L+              R  I    G         A  TGV + L L
Sbjct: 127 VNARVNNSDPYSVALSELGDRQNESYLNFARKRIKNPEGGLYLAVTLLAGITGVVITLCL 186

Query: 361 LLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG---------------------- 398
           +L+   S+  IRRS +FEVF++TH  +++ ++ L  HG                      
Sbjct: 187 ILIITSSTKTIRRS-YFEVFWYTHHLFVIFFIGLAIHGAERIVRGQTAESLAVHNITVCE 245

Query: 399 ---------------------PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLP 437
                                P  WKW++ P  L+  E+ +    S+   V I +V   P
Sbjct: 246 QKISEWGKIKECPIPQFAGNPPMTWKWIVGPMFLYLCERLVRFWRSQQKVV-ITKVVTHP 304

Query: 438 SKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAPEQKDTIWLHIRSQGQWT 497
            K   L +K+  F     G Y+++  P +++ EWHPFT++SAPE+ D   +HIR  G WT
Sbjct: 305 FKTIELQMKKKGF-KMEVGQYIFVKCPKVSKLEWHPFTLTSAPEE-DFFSIHIRIVGDWT 362

Query: 498 NRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTPT 557
             L+ +        + + +L                            K  +DGP+GT +
Sbjct: 363 EGLFNACGCDKQEFQDAWKLP---------------------------KIAVDGPFGTAS 395

Query: 558 RRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKVD 617
             +F+ E  +L+GAGIG+TPFASIL+S+ Y++         C ++       N+KL K+ 
Sbjct: 396 EDVFSYEVVMLVGAGIGVTPFASILKSVWYKY---------CNNA------TNLKLKKIY 440

Query: 618 FIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMALD 677
           F W+ RD  +FEWF  LL  LE  Q +E     FL  ++Y+T   G ++ +A    +  D
Sbjct: 441 FYWLCRDTHAFEWFADLLQLLE-SQMQERNNAGFLSYNIYLT---GWDESQANHFAVHHD 496

Query: 678 LLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKG-KVQVFFCGSPALAKVL 731
                E+KD ITGL+ +T  GRP+W   F+ +A++    ++ VF CG  ALA+ L
Sbjct: 497 -----EEKDVITGLKQKTLYGRPNWDNEFKTIASQHPNTRIGVFLCGPEALAETL 546


>gi|11136626 NADPH oxidase 3 [Homo sapiens]
          Length = 568

 Score =  209 bits (531), Expect = 1e-53
 Identities = 160/560 (28%), Positives = 255/560 (45%), Gaps = 121/560 (21%)

Query: 245 LGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLP----LDQNIQFHQLMG 300
           LG+++  A+    CLNF+C  I + + R  ++++R T +    P    LD+N++FH+L+ 
Sbjct: 47  LGSTLAWARASALCLNFNCMLILIPVSRNLISFIRGTSICCRGPWRRQLDKNLRFHKLVA 106

Query: 301 YVVVGLSLVHTVAHTVNFVLQAQAEASPFQFWELLLT------------------TRPGI 342
           Y +   + +H VAH  N      +++   Q     L+                  T    
Sbjct: 107 YGIAVNATIHIVAHFFNLERYHWSQSEEAQGLLAALSKLGNTPNESYLNPVRTFPTNTTT 166

Query: 343 GWVHGSASPTGVALLLLLLLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG---- 398
             +   A  TG+ + L L+L+   S+  IR++  +E+F++TH  +++ +L L  HG    
Sbjct: 167 ELLRTIAGVTGLVISLALVLIMTSSTEFIRQAS-YELFWYTHHVFIVFFLSLAIHGTGRI 225

Query: 399 ---------------------------------------PNFWKWLLVPGILFFLEKAIG 419
                                                  P+ WKW+L P +L+  E+ I 
Sbjct: 226 VRGQTQDSLSLHNITFCRDRYAEWQTVAQCPVPQFSGKEPSAWKWILGPVVLYACERIIR 285

Query: 420 LAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSA 479
               +   V I +V   PS V  L +K+  F    PG Y+ +  P I+  EWHPFT++SA
Sbjct: 286 FWRFQQEVV-ITKVVSHPSGVLELHMKKRGF-KMAPGQYILVQCPAISSLEWHPFTLTSA 343

Query: 480 PEQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRLSRSVTMRKSQRSSKGSEILLEK 539
           P Q+D   +HIR+ G WT  L E+F A     +    L R                    
Sbjct: 344 P-QEDFFSVHIRAAGDWTAALLEAFGAEGQALQEPWSLPRLA------------------ 384

Query: 540 HKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSC 599
                    +DGP+GT    +F     V + AGIG+TPFA++L+SI Y+          C
Sbjct: 385 ---------VDGPFGTALTDVFHYPVCVCVAAGIGVTPFAALLKSIWYK----------C 425

Query: 600 QHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMT 659
             +     Q  +KL KV F WI RD R+FEWF  LL  LE   +E+ +   FL  H+++T
Sbjct: 426 SEA-----QTPLKLSKVYFYWICRDARAFEWFADLLLSLETRMSEQGK-THFLSYHIFLT 479

Query: 660 SALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVA-AEKKGKVQ 718
              G ++ +A+ + +  D     E  D ITGL+ +T  GRP+W+  F+++A       + 
Sbjct: 480 ---GWDENQALHIALHWD-----ENTDVITGLKQKTFYGRPNWNNEFKQIAYNHPSSSIG 531

Query: 719 VFFCGSPALAKVLKGHCEKF 738
           VFFCG  AL++ L+  C  +
Sbjct: 532 VFFCGPKALSRTLQKMCHLY 551


>gi|7669510 NADPH oxidase 1 isoform long variant [Homo sapiens]
          Length = 515

 Score =  176 bits (447), Expect = 5e-44
 Identities = 163/620 (26%), Positives = 251/620 (40%), Gaps = 199/620 (32%)

Query: 216 NHRSQLFCLATYAGLHVLLFGLAASAHRD----------LGASVMVAKGCGQCLNFDCSF 265
           NH   +  L  + GL+V LF  A   +            LG+++  A+    CLNF+ + 
Sbjct: 7   NHWFSVLFLVVWLGLNVFLFVDAFLKYEKADKYYYTRKILGSTLACARASALCLNFNSTL 66

Query: 266 IAVLMLRRCLTWLRAT--WLAQVL--PLDQNIQFHQLMGYVVVGLSLVHTVAHTVNFVLQ 321
           I + + R  L++LR T  + ++ L   LD N+ FH+L+ Y++   + +H +AH  NF   
Sbjct: 67  ILLPVCRNLLSFLRGTCSFCSRTLRKQLDHNLTFHKLVAYMICLHTAIHIIAHLFNFDCY 126

Query: 322 AQAEASPFQFWELLLTT-----RPGIGWVH---------------GSASPTGVALLLLLL 361
           +++  +       +L++     + G  W++                 A  TGV + + L+
Sbjct: 127 SRSRQATDGSLASILSSLSHDEKKGGSWLNPIQSRNTTVEYVTFTSIAGLTGVIMTIALI 186

Query: 362 LMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFHG----------------------- 398
           LM   ++  IRRS +FEVF++TH  ++   L L  HG                       
Sbjct: 187 LMVTSATEFIRRS-YFEVFWYTHHLFIFYILGLGIHGIGGIVRGQTEESMNESHPRKCAE 245

Query: 399 ---------------------PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLP 437
                                P  WKW+L P IL+  E+ +    S+   V I +V + P
Sbjct: 246 SFEMWDDRDSHCRRPKFEGHPPESWKWILAPVILYICERILRFYRSQQKVV-ITKVVMHP 304

Query: 438 SKVTHLLIKRPPFFHYRPGDYLYLNIPTIARYEWHPFTISSAPEQKDTIWLHIRSQGQWT 497
           SKV  L + +  F     G Y+++N P+I+  EWHPFT++SAPE+ D   +HIR+ G WT
Sbjct: 305 SKVLELQMNKRGF-SMEVGQYIFVNCPSISLLEWHPFTLTSAPEE-DFFSIHIRAAGDWT 362

Query: 498 NRLYESFKAS-DPLGRGSKRLSRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTP 556
             L  +F+    P+ R                                    +DGP+GT 
Sbjct: 363 ENLIRAFEQQYSPIPR----------------------------------IEVDGPFGTA 388

Query: 557 TRRIFASEHAVLIGAGIGITPFASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKV 616
           +  +F  E AVL+GAGIG+TPFASIL+SI Y+ Q   H               N+K  KV
Sbjct: 389 SEDVFQYEVAVLVGAGIGVTPFASILKSIWYKFQCADH---------------NLKTKKV 433

Query: 617 DFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMAL 676
               +N D+                                                 A 
Sbjct: 434 GHAALNFDK-------------------------------------------------AT 444

Query: 677 DLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVA-AEKKGKVQVFFCGSPALAKVLKGHC 735
           D++   ++K S          GRP W   F  +A +  K  V VF CG   LAK L+  C
Sbjct: 445 DIVTGLKQKTSF---------GRPMWDNEFSTIATSHPKSVVGVFLCGPRTLAKSLRKCC 495

Query: 736 EKFG--------FRFFQENF 747
            ++         F F +ENF
Sbjct: 496 HRYSSLDPRKVQFYFNKENF 515


>gi|219842348 NADPH oxidase 4 isoform c [Homo sapiens]
          Length = 554

 Score =  119 bits (298), Expect = 1e-26
 Identities = 101/349 (28%), Positives = 150/349 (42%), Gaps = 64/349 (18%)

Query: 399 PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDY 458
           P  W W+  P  L+  E+      S    V I+ V   PS V  + + +  F   RPG Y
Sbjct: 257 PQTWLWISGPLCLYCAERLYRYIRSNKP-VTIISVISHPSDVMEIRMVKENF-KARPGQY 314

Query: 459 LYLNIPTIARYEWHPFTISSAP-EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRL 517
           + L+ P+++  E HPFT++  P E K T  +H++  G WT R  +               
Sbjct: 315 ITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPP---------- 364

Query: 518 SRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITP 577
                      SS+ SEIL         K YIDGP+G+P       E ++ +  GIG+TP
Sbjct: 365 -----------SSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTP 413

Query: 578 FASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTK 637
           FASIL +++                W        KL ++ FIW+ RD +SF WF  LL  
Sbjct: 414 FASILNTLL--------------DDW-----KPYKLRRLYFIWVCRDIQSFRWFADLLCM 454

Query: 638 LEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQP 697
           L     +E +   ++ + +Y++   G    K IG              +    L +R   
Sbjct: 455 LHNKFWQENR-PDYVNIQLYLSQTDG--IQKIIG--------------EKYHALNSRLFI 497

Query: 698 GRPDWSKVFQKVAAEKKGK-VQVFFCGSPALAKV---LKGHCEKFGFRF 742
           GRP W  +F ++A   +GK V VF CG  +L+K    L      +G RF
Sbjct: 498 GRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSYGTRF 546



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 31/174 (17%)

Query: 242 HRDLGASVMVAKGCGQCLNFDCSFIAVLMLRRCLTWLRATWLAQVLP-------LDQNIQ 294
           H+ LG  + +++     LN +CS I + M R  L +LR +   Q +P       LD++  
Sbjct: 23  HQMLGLGLCLSRASASVLNLNCSLILLPMCRTLLAYLRGS---QKVPSRRTRRLLDKSRT 79

Query: 295 FHQLMGYVVVGLSLVHTVAHTVN-----------FVLQAQAEASPFQFWELLLTTRPGIG 343
           FH   G  +   S VH  AH VN           FV    A        +LL TT PG+ 
Sbjct: 80  FHITCGVTICIFSGVHVAAHLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGL- 138

Query: 344 WVHGSASPTGVALLLLLLLMFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFH 397
                   TGV ++++L LM   S+  IR S ++++F++TH  + + ++LL  H
Sbjct: 139 --------TGVCMVVVLFLMITASTYAIRVS-NYDIFWYTHNLFFVFYMLLTLH 183


>gi|8393843 NADPH oxidase 4 isoform a [Homo sapiens]
          Length = 578

 Score =  119 bits (298), Expect = 1e-26
 Identities = 101/349 (28%), Positives = 150/349 (42%), Gaps = 64/349 (18%)

Query: 399 PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDY 458
           P  W W+  P  L+  E+      S    V I+ V   PS V  + + +  F   RPG Y
Sbjct: 281 PQTWLWISGPLCLYCAERLYRYIRSNKP-VTIISVISHPSDVMEIRMVKENF-KARPGQY 338

Query: 459 LYLNIPTIARYEWHPFTISSAP-EQKDTIWLHIRSQGQWTNRLYESFKASDPLGRGSKRL 517
           + L+ P+++  E HPFT++  P E K T  +H++  G WT R  +               
Sbjct: 339 ITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTERFRDLLLPP---------- 388

Query: 518 SRSVTMRKSQRSSKGSEILLEKHKFCNIKCYIDGPYGTPTRRIFASEHAVLIGAGIGITP 577
                      SS+ SEIL         K YIDGP+G+P       E ++ +  GIG+TP
Sbjct: 389 -----------SSQDSEILPFIQSRNYPKLYIDGPFGSPFEESLNYEVSLCVAGGIGVTP 437

Query: 578 FASILQSIMYRHQKRKHTCPSCQHSWIEGVQDNMKLHKVDFIWINRDQRSFEWFVSLLTK 637
           FASIL +++                W        KL ++ FIW+ RD +SF WF  LL  
Sbjct: 438 FASILNTLL--------------DDW-----KPYKLRRLYFIWVCRDIQSFRWFADLLCM 478

Query: 638 LEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIGLQMALDLLANKEKKDSITGLQTRTQP 697
           L     +E +   ++ + +Y++   G    K IG              +    L +R   
Sbjct: 479 LHNKFWQENR-PDYVNIQLYLSQTDG--IQKIIG--------------EKYHALNSRLFI 521

Query: 698 GRPDWSKVFQKVAAEKKGK-VQVFFCGSPALAKV---LKGHCEKFGFRF 742
           GRP W  +F ++A   +GK V VF CG  +L+K    L      +G RF
Sbjct: 522 GRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKTLHKLSNQNNSYGTRF 570



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 41/215 (19%)

Query: 211 RAYWHNHRSQLFCLATYAGLHVLLFGLAASA----------HRDLGASVMVAKGCGQCLN 260
           R++  N   +  CL  +  ++VLLF                H+ LG  + +++     LN
Sbjct: 6   RSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLN 65

Query: 261 FDCSFIAVLMLRRCLTWLRATWLAQVLP-------LDQNIQFHQLMGYVVVGLSLVHTVA 313
            +CS I + M R  L +LR +   Q +P       LD++  FH   G  +   S VH  A
Sbjct: 66  LNCSLILLPMCRTLLAYLRGS---QKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAA 122

Query: 314 HTVN-----------FVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLLLL 362
           H VN           FV    A        +LL TT PG+         TGV ++++L L
Sbjct: 123 HLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGL---------TGVCMVVVLFL 173

Query: 363 MFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFH 397
           M   S+  IR S ++++F++TH  + + ++LL  H
Sbjct: 174 MITASTYAIRVS-NYDIFWYTHNLFFVFYMLLTLH 207


>gi|219842346 NADPH oxidase 4 isoform b [Homo sapiens]
          Length = 538

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 60/215 (27%), Positives = 96/215 (44%), Gaps = 41/215 (19%)

Query: 211 RAYWHNHRSQLFCLATYAGLHVLLFGLAASA----------HRDLGASVMVAKGCGQCLN 260
           R++  N   +  CL  +  ++VLLF                H+ LG  + +++     LN
Sbjct: 6   RSWLANEGVKHLCLFIWLSMNVLLFWKTFLLYNQGPEYHYLHQMLGLGLCLSRASASVLN 65

Query: 261 FDCSFIAVLMLRRCLTWLRATWLAQVLP-------LDQNIQFHQLMGYVVVGLSLVHTVA 313
            +CS I + M R  L +LR +   Q +P       LD++  FH   G  +   S VH  A
Sbjct: 66  LNCSLILLPMCRTLLAYLRGS---QKVPSRRTRRLLDKSRTFHITCGVTICIFSGVHVAA 122

Query: 314 HTVN-----------FVLQAQAEASPFQFWELLLTTRPGIGWVHGSASPTGVALLLLLLL 362
           H VN           FV    A        +LL TT PG+         TGV ++++L L
Sbjct: 123 HLVNALNFSVNYSEDFVELNAARYRDEDPRKLLFTTVPGL---------TGVCMVVVLFL 173

Query: 363 MFICSSSCIRRSGHFEVFYWTHLSYLLVWLLLIFH 397
           M   S+  IR S ++++F++TH  + + ++LL  H
Sbjct: 174 MITASTYAIRVS-NYDIFWYTHNLFFVFYMLLTLH 207



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 34/102 (33%), Positives = 51/102 (50%), Gaps = 3/102 (2%)

Query: 399 PNFWKWLLVPGILFFLEKAIGLAVSRMAAVCIMEVNLLPSKVTHLLIKRPPFFHYRPGDY 458
           P  W W+  P  L+  E+      S    V I+ V   PS V  + + +  F   RPG Y
Sbjct: 281 PQTWLWISGPLCLYCAERLYRYIRSNKP-VTIISVISHPSDVMEIRMVKENF-KARPGQY 338

Query: 459 LYLNIPTIARYEWHPFTISSAP-EQKDTIWLHIRSQGQWTNR 499
           + L+ P+++  E HPFT++  P E K T  +H++  G WT R
Sbjct: 339 ITLHCPSVSALENHPFTLTMCPTETKATFGVHLKIVGDWTER 380



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 41/135 (30%), Positives = 62/135 (45%), Gaps = 21/135 (15%)

Query: 612 KLHKVDFIWINRDQRSFEWFVSLLTKLEMDQAEEAQYGRFLELHMYMTSALGKNDMKAIG 671
           KL ++ FIW+ RD +SF WF  LL  L     +E +   ++ + +Y++   G    K IG
Sbjct: 413 KLRRLYFIWVCRDIQSFRWFADLLCMLHNKFWQENR-PDYVNIQLYLSQTDG--IQKIIG 469

Query: 672 LQMALDLLANKEKKDSITGLQTRTQPGRPDWSKVFQKVAAEKKGK-VQVFFCGSPALAKV 730
                         +    L +R   GRP W  +F ++A   +GK V VF CG  +L+K 
Sbjct: 470 --------------EKYHALNSRLFIGRPRWKLLFDEIAKYNRGKTVGVFCCGPNSLSKT 515

Query: 731 ---LKGHCEKFGFRF 742
              L      +G RF
Sbjct: 516 LHKLSNQNNSYGTRF 530


>gi|40254415 guanylate cyclase activator 1A (retina) [Homo sapiens]
          Length = 201

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 44/170 (25%), Positives = 79/170 (46%), Gaps = 33/170 (19%)

Query: 25  GEISLQEFKAALHVKE-----SFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G+++L EF+    +K      S + E+ F  FD ++ G I   E   AL+L++ G    K
Sbjct: 32  GQLTLYEFRQFFGLKNLSPSASQYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVEQK 91

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRES 139
           L++ F++YD+D                            G+G ID DEL T++Q+    +
Sbjct: 92  LRWYFKLYDVD----------------------------GNGCIDRDELLTIIQAIRAIN 123

Query: 140 AISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMENLTIS 189
             S      ++ T  +F   D +G+G ++ EE  + +Q+   +++ LT S
Sbjct: 124 PCSDTTMTAEEFTDTVFSKIDVNGDGELSLEEFIEGVQKDQMLLDTLTRS 173


>gi|4506025 protein phosphatase 3, regulatory subunit B, alpha
           isoform 1 [Homo sapiens]
          Length = 170

 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 43/173 (24%), Positives = 79/173 (45%), Gaps = 33/173 (19%)

Query: 1   MSAEEDARWLRWVTQQFKTI-AGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTI 59
           M +  DA  ++ + ++FK +     G +S++EF +   ++++   +R   +FD+D +G +
Sbjct: 11  MCSHFDADEIKRLGKRFKKLDLDNSGSLSVEEFMSLPELQQNPLVQRVIDIFDTDGNGEV 70

Query: 60  TLQELQEALT-LLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGT 118
             +E  E ++   + G    KL+F F++YD+D                            
Sbjct: 71  DFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMD---------------------------- 102

Query: 119 GSGSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEE 171
             G I   EL  VL+  +     +L D +L Q+      +AD DG+G I+FEE
Sbjct: 103 KDGYISNGELFQVLKMMVGN---NLKDTQLQQIVDKTIINADKDGDGRISFEE 152


>gi|98985795 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +S++EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|98985793 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +S++EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|98985791 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +S++EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|98985789 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +S++EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|98985787 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +S++EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|98985785 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +S++EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|98985783 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +S++EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|98985778 neurocalcin delta [Homo sapiens]
          Length = 193

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +S++EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISKAEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|19913443 hippocalcin-like 1 [Homo sapiens]
          Length = 193

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +++ EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISRSEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|19913441 hippocalcin-like 1 [Homo sapiens]
          Length = 193

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 40/171 (23%), Positives = 73/171 (42%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +++ EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           LK+ F +YD+D                            G+G I   E+  ++Q+  +  
Sbjct: 101 LKWAFSMYDLD----------------------------GNGYISRSEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|153945858 guanylate cyclase activator 1B (retina) [Homo sapiens]
          Length = 200

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 46/188 (24%), Positives = 79/188 (42%), Gaps = 50/188 (26%)

Query: 25  GEISLQEFKAALHVKE----SFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKL 80
           G + + EFK    V +    S + E  F  FD +   TI   E   AL L++ G+   KL
Sbjct: 35  GTLFMHEFKRFFKVTDDEEASQYVEGMFRAFDKNGDNTIDFLEYVAALNLVLRGTLEHKL 94

Query: 81  KFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQ------- 133
           K+ F++YD D                            G+G ID  EL  +++       
Sbjct: 95  KWTFKIYDKD----------------------------GNGCIDRLELLNIVEGIYQLKK 126

Query: 134 SCLRE-----SAISLPDEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVME--NL 186
           +C RE       +  P+E +D++ L +    D +G+G ++  E  +  +R   VM+   +
Sbjct: 127 ACRRELQTEQGQLLTPEEVVDRIFLLV----DENGDGQLSLNEFVEGARRDKWVMKMLQM 182

Query: 187 TISAAHWL 194
            ++ + WL
Sbjct: 183 DMNPSSWL 190


>gi|13375787 EF-hand calcium binding domain 1 isoform a [Homo
           sapiens]
          Length = 211

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 35/145 (24%), Positives = 62/145 (42%), Gaps = 33/145 (22%)

Query: 32  FKAALHVK----ESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLFQVY 87
           F+  LHV     +    +R F  FD D  G + + E    L+L + GS  +K+K+ F+V+
Sbjct: 53  FRNILHVTFGMTDDMIMDRVFRGFDKDNDGCVNVLEWIHGLSLFLRGSLEEKMKYCFEVF 112

Query: 88  DIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQ-SCLRESAISLPDE 146
           D++                            G G I  +E+  +L+ S L++ +   PDE
Sbjct: 113 DLN----------------------------GDGFISKEEMFHMLKNSLLKQPSEEDPDE 144

Query: 147 KLDQLTLALFESADADGNGAITFEE 171
            +  L     +  D D +G ++F +
Sbjct: 145 GIKDLVEITLKKMDHDHDGKLSFAD 169


>gi|19913446 hippocalcin [Homo sapiens]
          Length = 193

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 37/171 (21%)

Query: 25  GEISLQEFKAAL-----HVKESFFAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDK 79
           G +++ EFK        +   S FAE  F  FD++  GTI  +E   AL++   G    K
Sbjct: 41  GILNVDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGRLEQK 100

Query: 80  LKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLR-- 137
           L + F +YD+D                            G+G I  +E+  ++Q+  +  
Sbjct: 101 LMWAFSMYDLD----------------------------GNGYISREEMLEIVQAIYKMV 132

Query: 138 ESAISLPDEKL--DQLTLALFESADADGNGAITFEELRDELQRFPGVMENL 186
            S + +P+++   ++ T  +F   D + +G ++ EE     +  P ++  L
Sbjct: 133 SSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKSDPSIVRLL 183


>gi|33946291 lysophosphatidylcholine acyltransferase 1 [Homo
           sapiens]
          Length = 534

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 45/182 (24%), Positives = 75/182 (41%), Gaps = 43/182 (23%)

Query: 26  EISLQEFKAALHVKESFFAERFFALFDSDRSGTITLQELQEALTLLIH-GSPMDKLKFLF 84
           +I + EF A+L V  S   E  F+LFD   SG + L+E   AL+++      +D ++  F
Sbjct: 366 KIGIAEFAASLEVPVSDLLEDMFSLFDESGSGEVDLRECVVALSVVCRPARTLDTIQLAF 425

Query: 85  QVYDIDVCARQGASAGTEWGAGAGPHWASSPLGTGSGSIDPDELRTVLQSCLRESAISLP 144
           ++Y        GA                       GS+   +L  +L++ L  + +++ 
Sbjct: 426 KMY--------GAQE--------------------DGSVGEGDLSCILKTALGVAELTVT 457

Query: 145 DEKLDQLTLALFESADADGNGAITFEELRDELQRFPGVMEN-LTISAAHW----LTAPAP 199
           D         LF + D +  G ITF +     + +P   E  L     H+     T+PAP
Sbjct: 458 D---------LFRAIDQEEKGKITFADFHRFAEMYPAFAEEYLYPDQTHFESCAETSPAP 508

Query: 200 RP 201
            P
Sbjct: 509 IP 510


>gi|78190495 Kv channel interacting protein 3 isoform 2 [Homo
           sapiens]
          Length = 230

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 46/157 (29%)

Query: 43  FAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTE 102
           +A   F  FD+D +G I  ++    L++L+ G+  +KLK+ F +YDI+            
Sbjct: 104 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDIN------------ 151

Query: 103 WGAGAGPHWASSPLGTGSGSIDPDELRTVLQS-----------CLRESAISLPDEKLDQL 151
                             G I  +E+  +++S            LRE A   P E +++ 
Sbjct: 152 ----------------KDGYITKEEMLAIMKSIYDMMGRHTYPILREDA---PAEHVER- 191

Query: 152 TLALFESADADGNGAITFEELRDELQRFPGVMENLTI 188
               FE  D + +G +T EE  +  Q+   +M ++ +
Sbjct: 192 ---FFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQL 225


>gi|7305199 Kv channel interacting protein 3 isoform 1 [Homo
           sapiens]
          Length = 256

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 46/157 (29%)

Query: 43  FAERFFALFDSDRSGTITLQELQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTE 102
           +A   F  FD+D +G I  ++    L++L+ G+  +KLK+ F +YDI+            
Sbjct: 130 YAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDIN------------ 177

Query: 103 WGAGAGPHWASSPLGTGSGSIDPDELRTVLQS-----------CLRESAISLPDEKLDQL 151
                             G I  +E+  +++S            LRE A   P E +++ 
Sbjct: 178 ----------------KDGYITKEEMLAIMKSIYDMMGRHTYPILREDA---PAEHVER- 217

Query: 152 TLALFESADADGNGAITFEELRDELQRFPGVMENLTI 188
               FE  D + +G +T EE  +  Q+   +M ++ +
Sbjct: 218 ---FFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQL 251


>gi|22212896 protein phosphatase 3 regulatory subunit B, beta
           isoform [Homo sapiens]
          Length = 173

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 41/173 (23%), Positives = 71/173 (41%), Gaps = 33/173 (19%)

Query: 1   MSAEEDARWLRWVTQQFKTI-AGEDGEISLQEFKAALHVKESFFAERFFALFDSDRSGTI 59
           M +  D   ++ + ++FK +   + G +S++EF +   ++ +    R   +FD+D  G +
Sbjct: 14  MCSHFDNDEIKRLGRRFKKLDLDKSGSLSVEEFMSLPELRHNPLVRRVIDVFDTDGDGEV 73

Query: 60  TLQE-LQEALTLLIHGSPMDKLKFLFQVYDIDVCARQGASAGTEWGAGAGPHWASSPLGT 118
             +E +       + G    KL+F F +YD+D                            
Sbjct: 74  DFKEFILGTSQFSVKGDEEQKLRFAFSIYDMD---------------------------- 105

Query: 119 GSGSIDPDELRTVLQSCLRESAISLPDEKLDQLTLALFESADADGNGAITFEE 171
             G I   EL  VL+  +     +L D +L QL        D DG+G I+FEE
Sbjct: 106 KDGYISNGELFQVLKMMVGN---NLTDWQLQQLVDKTIIILDKDGDGKISFEE 155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.137    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,673,225
Number of Sequences: 37866
Number of extensions: 1355923
Number of successful extensions: 5037
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 66
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 4771
Number of HSP's gapped (non-prelim): 221
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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