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Search of human proteins with 20127524
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20127524 interleukin 1 family, member 7 isoform 1 proprotein
[Homo sapiens]
(218 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20127524 interleukin 1 family, member 7 isoform 1 proprotein ... 454 e-128
gi|27894296 interleukin 1 family, member 7 isoform 2 [Homo sapiens] 395 e-110
gi|27894302 interleukin 1 family, member 7 isoform 5 [Homo sapiens] 349 1e-96
gi|27894300 interleukin 1 family, member 7 isoform 4 [Homo sapiens] 345 2e-95
gi|27894298 interleukin 1 family, member 7 isoform 3 [Homo sapiens] 269 1e-72
gi|27894313 interleukin 1 family, member 8 isoform 2 [Homo sapiens] 91 8e-19
gi|9665234 interleukin 1 family, member 9 [Homo sapiens] 89 3e-18
gi|7657092 interleukin 1 family, member 6 (epsilon) [Homo sapiens] 82 3e-16
gi|27894310 interleukin 1 family, member 5 [Homo sapiens] 67 2e-11
gi|6912432 interleukin 1 family, member 5 [Homo sapiens] 67 2e-11
gi|27894307 interleukin 1 family, member 10 [Homo sapiens] 61 8e-10
gi|27894304 interleukin 1 family, member 10 [Homo sapiens] 61 8e-10
gi|27894319 interleukin 1 receptor antagonist isoform 1 precurso... 58 7e-09
gi|27894317 interleukin 1 receptor antagonist isoform 2 [Homo sa... 58 7e-09
gi|10835147 interleukin 1 receptor antagonist isoform 3 [Homo sa... 58 7e-09
gi|27894321 interleukin 1 receptor antagonist isoform 4 [Homo sa... 57 1e-08
gi|20070252 interleukin 1 family, member 8 isoform 1 [Homo sapiens] 49 3e-06
gi|10835145 interleukin 1, beta proprotein [Homo sapiens] 39 0.004
gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Ho... 30 1.2
gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Ho... 30 1.2
gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo ... 30 1.6
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 30 1.6
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo... 30 2.1
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo... 30 2.1
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo... 30 2.1
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor... 30 2.1
gi|50345997 E1A binding protein p300 [Homo sapiens] 30 2.1
gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithor... 30 2.1
gi|239747259 PREDICTED: hypothetical protein [Homo sapiens] 29 2.7
gi|194248077 Kruppel-like factor 4 (gut) [Homo sapiens] 29 3.5
>gi|20127524 interleukin 1 family, member 7 isoform 1 proprotein
[Homo sapiens]
Length = 218
Score = 454 bits (1168), Expect = e-128
Identities = 218/218 (100%), Positives = 218/218 (100%)
Query: 1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKF 60
MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKF
Sbjct: 1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKF 60
Query: 61 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL 120
SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL
Sbjct: 61 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL 120
Query: 121 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS 180
YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
Sbjct: 121 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS 180
Query: 181 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD 218
CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
Sbjct: 181 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD 218
>gi|27894296 interleukin 1 family, member 7 isoform 2 [Homo sapiens]
Length = 197
Score = 395 bits (1015), Expect = e-110
Identities = 196/218 (89%), Positives = 196/218 (89%), Gaps = 21/218 (9%)
Query: 1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKF 60
MSFVGENSGVKMGSEDWEKDEPQCCLE PKVKNLNPKKF
Sbjct: 1 MSFVGENSGVKMGSEDWEKDEPQCCLE---------------------GPKVKNLNPKKF 39
Query: 61 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL 120
SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL
Sbjct: 40 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL 99
Query: 121 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS 180
YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
Sbjct: 100 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS 159
Query: 181 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD 218
CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
Sbjct: 160 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD 197
>gi|27894302 interleukin 1 family, member 7 isoform 5 [Homo sapiens]
Length = 192
Score = 349 bits (895), Expect = 1e-96
Identities = 169/169 (100%), Positives = 169/169 (100%)
Query: 50 PKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPI 109
PKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPI
Sbjct: 24 PKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPI 83
Query: 110 LLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLES 169
LLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLES
Sbjct: 84 LLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLES 143
Query: 170 AAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD 218
AAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
Sbjct: 144 AAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD 192
>gi|27894300 interleukin 1 family, member 7 isoform 4 [Homo sapiens]
Length = 178
Score = 345 bits (884), Expect = 2e-95
Identities = 173/218 (79%), Positives = 176/218 (80%), Gaps = 40/218 (18%)
Query: 1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKF 60
MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMN
Sbjct: 1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMN---------------- 44
Query: 61 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCL 120
++ +IFFALASSLSSASAEKGSPILLGVSKGEFCL
Sbjct: 45 ------------------------FVHTKIFFALASSLSSASAEKGSPILLGVSKGEFCL 80
Query: 121 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS 180
YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS
Sbjct: 81 YCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTS 140
Query: 181 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD 218
CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
Sbjct: 141 CNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD 178
>gi|27894298 interleukin 1 family, member 7 isoform 3 [Homo sapiens]
Length = 157
Score = 269 bits (688), Expect = 1e-72
Identities = 130/130 (100%), Positives = 130/130 (100%)
Query: 89 EIFFALASSLSSASAEKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKE 148
EIFFALASSLSSASAEKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKE
Sbjct: 28 EIFFALASSLSSASAEKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKE 87
Query: 149 SARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCK 208
SARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCK
Sbjct: 88 SARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCK 147
Query: 209 AEMSPSEVSD 218
AEMSPSEVSD
Sbjct: 148 AEMSPSEVSD 157
Score = 65.1 bits (157), Expect = 4e-11
Identities = 42/99 (42%), Positives = 55/99 (55%), Gaps = 10/99 (10%)
Query: 1 MSFVGENSGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKF 60
MSFVGENSGVKMGSEDWEKDEPQCCLE+ SL + + SP + ++ +F
Sbjct: 1 MSFVGENSGVKMGSEDWEKDEPQCCLEEIF---FALASSLSSASAEKGSPILLGVSKGEF 57
Query: 61 SIH-----DQDHKVLVLDSGNL--IAVPDKNYIRPEIFF 92
++ Q H L L L +A ++ RP IF+
Sbjct: 58 CLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFY 96
>gi|27894313 interleukin 1 family, member 8 isoform 2 [Homo sapiens]
Length = 157
Score = 90.9 bits (224), Expect = 8e-19
Identities = 48/135 (35%), Positives = 81/135 (60%), Gaps = 4/135 (2%)
Query: 57 PKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSAS-AEKGSPILLGVSK 115
PK ++I D V VL +LIA P I+P +A + S EKG+ + LG+
Sbjct: 9 PKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVYLGIKG 68
Query: 116 GEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGW 175
+ CL+C + +G+ P+LQLK++ +M L +K+ A++PF+F+ + GS ++ +S ++PGW
Sbjct: 69 KDLCLFCAEIQGK--PTLQLKEKNIMDLYVEKK-AQKPFLFFHNKEGSTSVFQSVSYPGW 125
Query: 176 FICTSCNCNEPVGVT 190
FI TS +P+ +T
Sbjct: 126 FIATSTTSGQPIFLT 140
>gi|9665234 interleukin 1 family, member 9 [Homo sapiens]
Length = 169
Score = 89.0 bits (219), Expect = 3e-18
Identities = 51/133 (38%), Positives = 77/133 (57%), Gaps = 5/133 (3%)
Query: 61 SIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAE-KGSPILLGVSKGEFC 119
+I+D + +V L NL+AVP + + P + A + +G PI LG+ E C
Sbjct: 26 TINDLNQQVWTLQGQNLVAVPRSDSVTPVTVAVITCKYPEALEQGRGDPIYLGIQNPEMC 85
Query: 120 LYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICT 179
LYC+K Q P+LQLK++K+M L Q E + PF+FYRA+ G + LES A P WFI +
Sbjct: 86 LYCEKVGEQ--PTLQLKEQKIMDLYGQPEPVK-PFLFYRAKTGRTSTLESVAFPDWFIAS 142
Query: 180 SCNCNEPVGVTDK 192
S ++P+ +T +
Sbjct: 143 S-KRDQPIILTSE 154
>gi|7657092 interleukin 1 family, member 6 (epsilon) [Homo sapiens]
Length = 158
Score = 82.4 bits (202), Expect = 3e-16
Identities = 56/147 (38%), Positives = 79/147 (53%), Gaps = 6/147 (4%)
Query: 57 PKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEK--GSPILLGVS 114
P++ SI D +H+V VL LIAVP K+ + P + AL S + EK G+PI LG++
Sbjct: 10 PQQGSIQDINHRVWVLQDQTLIAVPRKDRMSP-VTIALISCRHVETLEKDRGNPIYLGLN 68
Query: 115 KGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPG 174
CL C K Q P+LQLK++ +M L Q E + F+FY +Q G + ES A PG
Sbjct: 69 GLNLCLMCAKVGDQ--PTLQLKEKDIMDLYNQPEPVKS-FLFYHSQSGRNSTFESVAFPG 125
Query: 175 WFICTSCNCNEPVGVTDKFENRKHIEF 201
WFI S P+ +T + +F
Sbjct: 126 WFIAVSSEGGCPLILTQELGKANTTDF 152
>gi|27894310 interleukin 1 family, member 5 [Homo sapiens]
Length = 155
Score = 66.6 bits (161), Expect = 2e-11
Identities = 49/139 (35%), Positives = 71/139 (51%), Gaps = 11/139 (7%)
Query: 60 FSIHDQDHKVLVLDSGNLIA--VPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGE 117
F + D KVL L + L+A + I+ E + + AS SP++LGV G
Sbjct: 9 FRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASL---SPVILGVQGGS 65
Query: 118 FCLYCDKDKGQSHPSLQLKKEKLMKL-AAQKESARRPFIFYRAQVGSWNMLESAAHPGWF 176
CL C + P+L L+ +M+L KES + F FYR +G + ESAA+PGWF
Sbjct: 66 QCLSCGVGQ---EPTLTLEPVNIMELYLGAKES--KSFTFYRRDMGLTSSFESAAYPGWF 120
Query: 177 ICTSCNCNEPVGVTDKFEN 195
+CT ++PV +T EN
Sbjct: 121 LCTVPEADQPVRLTQLPEN 139
>gi|6912432 interleukin 1 family, member 5 [Homo sapiens]
Length = 155
Score = 66.6 bits (161), Expect = 2e-11
Identities = 49/139 (35%), Positives = 71/139 (51%), Gaps = 11/139 (7%)
Query: 60 FSIHDQDHKVLVLDSGNLIA--VPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGE 117
F + D KVL L + L+A + I+ E + + AS SP++LGV G
Sbjct: 9 FRMKDSALKVLYLHNNQLLAGGLHAGKVIKGEEISVVPNRWLDASL---SPVILGVQGGS 65
Query: 118 FCLYCDKDKGQSHPSLQLKKEKLMKL-AAQKESARRPFIFYRAQVGSWNMLESAAHPGWF 176
CL C + P+L L+ +M+L KES + F FYR +G + ESAA+PGWF
Sbjct: 66 QCLSCGVGQ---EPTLTLEPVNIMELYLGAKES--KSFTFYRRDMGLTSSFESAAYPGWF 120
Query: 177 ICTSCNCNEPVGVTDKFEN 195
+CT ++PV +T EN
Sbjct: 121 LCTVPEADQPVRLTQLPEN 139
>gi|27894307 interleukin 1 family, member 10 [Homo sapiens]
Length = 152
Score = 60.8 bits (146), Expect = 8e-10
Identities = 36/97 (37%), Positives = 52/97 (53%), Gaps = 3/97 (3%)
Query: 108 PILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNML 167
PI LG+ G CL C + + PSLQL+ + +L E A R F F+++ GS L
Sbjct: 56 PIFLGIQGGSRCLACVET--EEGPSLQLEDVNIEELYKGGEEATR-FTFFQSSSGSAFRL 112
Query: 168 ESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ 204
E+AA PGWF+C +PV +T + E +F F+
Sbjct: 113 EAAAWPGWFLCGPAEPQQPVQLTKESEPSARTKFYFE 149
>gi|27894304 interleukin 1 family, member 10 [Homo sapiens]
Length = 152
Score = 60.8 bits (146), Expect = 8e-10
Identities = 36/97 (37%), Positives = 52/97 (53%), Gaps = 3/97 (3%)
Query: 108 PILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNML 167
PI LG+ G CL C + + PSLQL+ + +L E A R F F+++ GS L
Sbjct: 56 PIFLGIQGGSRCLACVET--EEGPSLQLEDVNIEELYKGGEEATR-FTFFQSSSGSAFRL 112
Query: 168 ESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ 204
E+AA PGWF+C +PV +T + E +F F+
Sbjct: 113 EAAAWPGWFLCGPAEPQQPVQLTKESEPSARTKFYFE 149
>gi|27894319 interleukin 1 receptor antagonist isoform 1 precursor
[Homo sapiens]
Length = 177
Score = 57.8 bits (138), Expect = 7e-09
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 53 KNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIR-PEIFFALASSLSSASAEKGSPILL 111
K+ + F I D + K L + L+A Y++ P + L + E + + L
Sbjct: 31 KSSKMQAFRIWDVNQKTFYLRNNQLVA----GYLQGPNV--NLEEKIDVVPIEPHA-LFL 83
Query: 112 GVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAA 171
G+ G+ CL C K ++ LQL+ + L+ ++ +R F F R+ G ESAA
Sbjct: 84 GIHGGKMCLSCVKSGDETR--LQLEAVNITDLSENRKQDKR-FAFIRSDSGPTTSFESAA 140
Query: 172 HPGWFICTSCNCNEPVGVTD 191
PGWF+CT+ ++PV +T+
Sbjct: 141 CPGWFLCTAMEADQPVSLTN 160
>gi|27894317 interleukin 1 receptor antagonist isoform 2 [Homo
sapiens]
Length = 180
Score = 57.8 bits (138), Expect = 7e-09
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 53 KNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIR-PEIFFALASSLSSASAEKGSPILL 111
K+ + F I D + K L + L+A Y++ P + L + E + + L
Sbjct: 34 KSSKMQAFRIWDVNQKTFYLRNNQLVA----GYLQGPNV--NLEEKIDVVPIEPHA-LFL 86
Query: 112 GVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAA 171
G+ G+ CL C K ++ LQL+ + L+ ++ +R F F R+ G ESAA
Sbjct: 87 GIHGGKMCLSCVKSGDETR--LQLEAVNITDLSENRKQDKR-FAFIRSDSGPTTSFESAA 143
Query: 172 HPGWFICTSCNCNEPVGVTD 191
PGWF+CT+ ++PV +T+
Sbjct: 144 CPGWFLCTAMEADQPVSLTN 163
>gi|10835147 interleukin 1 receptor antagonist isoform 3 [Homo
sapiens]
Length = 159
Score = 57.8 bits (138), Expect = 7e-09
Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 11/140 (7%)
Query: 53 KNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIR-PEIFFALASSLSSASAEKGSPILL 111
K+ + F I D + K L + L+A Y++ P + L + E + + L
Sbjct: 13 KSSKMQAFRIWDVNQKTFYLRNNQLVA----GYLQGPNV--NLEEKIDVVPIEPHA-LFL 65
Query: 112 GVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAA 171
G+ G+ CL C K ++ LQL+ + L+ ++ +R F F R+ G ESAA
Sbjct: 66 GIHGGKMCLSCVKSGDETR--LQLEAVNITDLSENRKQDKR-FAFIRSDSGPTTSFESAA 122
Query: 172 HPGWFICTSCNCNEPVGVTD 191
PGWF+CT+ ++PV +T+
Sbjct: 123 CPGWFLCTAMEADQPVSLTN 142
>gi|27894321 interleukin 1 receptor antagonist isoform 4 [Homo
sapiens]
Length = 143
Score = 57.0 bits (136), Expect = 1e-08
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 3/83 (3%)
Query: 109 ILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLE 168
+ LG+ G+ CL C K ++ LQL+ + L+ ++ +R F F R+ G E
Sbjct: 47 LFLGIHGGKMCLSCVKSGDETR--LQLEAVNITDLSENRKQDKR-FAFIRSDSGPTTSFE 103
Query: 169 SAAHPGWFICTSCNCNEPVGVTD 191
SAA PGWF+CT+ ++PV +T+
Sbjct: 104 SAACPGWFLCTAMEADQPVSLTN 126
>gi|20070252 interleukin 1 family, member 8 isoform 1 [Homo sapiens]
Length = 164
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/81 (34%), Positives = 43/81 (53%), Gaps = 3/81 (3%)
Query: 57 PKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALA-SSLSSASAEKGSPILLGVSK 115
PK ++I D V VL +LIA P I+P +A + EKG+ + LG+
Sbjct: 9 PKSYAIRDSRQMVWVLSGNSLIAAPLSRSIKPVTLHLIACRDTEFSDKEKGNMVYLGIKG 68
Query: 116 GEFCLYCDKDKGQSHPSLQLK 136
+ CL+C + +G+ P+LQLK
Sbjct: 69 KDLCLFCAEIQGK--PTLQLK 87
>gi|10835145 interleukin 1, beta proprotein [Homo sapiens]
Length = 269
Score = 38.5 bits (88), Expect = 0.004
Identities = 41/146 (28%), Positives = 70/146 (47%), Gaps = 13/146 (8%)
Query: 45 FVHTSPKVKNLNPKKFSIHDQDHKVLVLDSG-NLIAVPDKNY-IRPEIFFALASSLSSAS 102
+VH +P V++LN ++ D K LV+ L A+ + + ++ F+++ S
Sbjct: 113 YVHDAP-VRSLN---CTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEES 168
Query: 103 AEKGSPILLGVSKGEFCLYCD-KDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQV 161
+K P+ LG+ + L C KD P+LQL E + K+ + F+F + ++
Sbjct: 169 NDK-IPVALGLKEKNLYLSCVLKD---DKPTLQL--ESVDPKNYPKKKMEKRFVFNKIEI 222
Query: 162 GSWNMLESAAHPGWFICTSCNCNEPV 187
+ ESA P W+I TS N PV
Sbjct: 223 NNKLEFESAQFPNWYISTSQAENMPV 248
>gi|217330639 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
sapiens]
Length = 880
Score = 30.4 bits (67), Expect = 1.2
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 1/90 (1%)
Query: 33 PLEPGPSLPTMNFVHTSPKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFF 92
P PS PT + H SP P + S +D H + +LD V ++ PE+
Sbjct: 575 PRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEV-L 633
Query: 93 ALASSLSSASAEKGSPILLGVSKGEFCLYC 122
S + A A +GSP L + YC
Sbjct: 634 CQQSLKAEAQALEGSPTQLPILADMLLYYC 663
>gi|217330622 phosphoinositide-3-kinase, regulatory subunit 5 [Homo
sapiens]
Length = 880
Score = 30.4 bits (67), Expect = 1.2
Identities = 26/90 (28%), Positives = 37/90 (41%), Gaps = 1/90 (1%)
Query: 33 PLEPGPSLPTMNFVHTSPKVKNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFF 92
P PS PT + H SP P + S +D H + +LD V ++ PE+
Sbjct: 575 PRSQTPSPPTDSPRHASPGELGTTPWEESTNDISHYLGMLDPWYERNVLGLMHLPPEV-L 633
Query: 93 ALASSLSSASAEKGSPILLGVSKGEFCLYC 122
S + A A +GSP L + YC
Sbjct: 634 CQQSLKAEAQALEGSPTQLPILADMLLYYC 663
>gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo
sapiens]
Length = 248
Score = 30.0 bits (66), Expect = 1.6
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 172 HPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ 204
H F+C C P G+ +FE RK+ E FQ
Sbjct: 94 HEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 126
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 30.0 bits (66), Expect = 1.6
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 172 HPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ 204
H F+C C P G+ +FE RK+ E FQ
Sbjct: 32 HEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64
Score = 28.1 bits (61), Expect = 6.0
Identities = 15/42 (35%), Positives = 24/42 (57%), Gaps = 7/42 (16%)
Query: 169 SAAHPGWFI-CTSCN-CNEPVGVTDKFENRKHIEFSFQPVCK 208
SA + W + C +C+ CN + + +KF +EF +PVCK
Sbjct: 265 SALNKAWCVNCFACSTCNTKLTLKNKF-----VEFDMKPVCK 301
>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
1 [Homo sapiens]
Length = 363
Score = 29.6 bits (65), Expect = 2.1
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 7/42 (16%)
Query: 169 SAAHPGWFI-CTSCN-CNEPVGVTDKFENRKHIEFSFQPVCK 208
SA + W + C SC+ CN + + +KF +EF +PVCK
Sbjct: 292 SALNKAWCVSCFSCSTCNSKLTLKNKF-----VEFDMKPVCK 328
Score = 29.3 bits (64), Expect = 2.7
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 172 HPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ 204
H F+C C P G+ +FE RK+ E FQ
Sbjct: 59 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ 91
>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
5 [Homo sapiens]
Length = 336
Score = 29.6 bits (65), Expect = 2.1
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 7/42 (16%)
Query: 169 SAAHPGWFI-CTSCN-CNEPVGVTDKFENRKHIEFSFQPVCK 208
SA + W + C SC+ CN + + +KF +EF +PVCK
Sbjct: 265 SALNKAWCVSCFSCSTCNSKLTLKNKF-----VEFDMKPVCK 301
Score = 29.3 bits (64), Expect = 2.7
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 172 HPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ 204
H F+C C P G+ +FE RK+ E FQ
Sbjct: 32 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ 64
>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
3 [Homo sapiens]
Length = 341
Score = 29.6 bits (65), Expect = 2.1
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 7/42 (16%)
Query: 169 SAAHPGWFI-CTSCN-CNEPVGVTDKFENRKHIEFSFQPVCK 208
SA + W + C SC+ CN + + +KF +EF +PVCK
Sbjct: 270 SALNKAWCVSCFSCSTCNSKLTLKNKF-----VEFDMKPVCK 306
Score = 29.3 bits (64), Expect = 2.7
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 172 HPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ 204
H F+C C P G+ +FE RK+ E FQ
Sbjct: 37 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ 69
>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
[Homo sapiens]
Length = 365
Score = 29.6 bits (65), Expect = 2.1
Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 7/42 (16%)
Query: 169 SAAHPGWFI-CTSCN-CNEPVGVTDKFENRKHIEFSFQPVCK 208
SA + W + C SC+ CN + + +KF +EF +PVCK
Sbjct: 294 SALNKAWCVSCFSCSTCNSKLTLKNKF-----VEFDMKPVCK 330
Score = 29.3 bits (64), Expect = 2.7
Identities = 13/33 (39%), Positives = 17/33 (51%)
Query: 172 HPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQ 204
H F+C C P G+ +FE RK+ E FQ
Sbjct: 61 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQ 93
>gi|50345997 E1A binding protein p300 [Homo sapiens]
Length = 2414
Score = 29.6 bits (65), Expect = 2.1
Identities = 11/34 (32%), Positives = 20/34 (58%)
Query: 29 PAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKFSI 62
P G P P++P VH++P ++N+NP + +
Sbjct: 2107 PQGQPGLQPPTMPGQQGVHSNPAMQNMNPMQAGV 2140
>gi|156104889 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 3 [Homo sapiens]
Length = 568
Score = 29.6 bits (65), Expect = 2.1
Identities = 39/153 (25%), Positives = 55/153 (35%), Gaps = 19/153 (12%)
Query: 8 SGVKMGSEDWEKDEPQCCLEDPAGSPLEPGPSLPTMNFVHTSPKVKNLNPKKFSIHDQDH 67
S K S D K + + PL+ +P M F P K P D
Sbjct: 216 SAFKEPSRDHNKSSKESSKKPKENKPLKEEKIVPKMAFKEPKPMSKEPKP--------DS 267
Query: 68 KVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGE---FCLYCDK 124
+L + SG P K RP I + + LS+ +K S L S L C
Sbjct: 268 NLLTITSGQDKKAPSK---RPPI--SDSEELSAKKRKKSSSEALFKSFSSAPPLILTCSA 322
Query: 125 DKGQSHPSLQLKKEKL---MKLAAQKESARRPF 154
DK Q +K K+ + + +K+S PF
Sbjct: 323 DKKQIKDKSHVKMGKVKIESETSEKKKSTLPPF 355
>gi|239747259 PREDICTED: hypothetical protein [Homo sapiens]
Length = 176
Score = 29.3 bits (64), Expect = 2.7
Identities = 12/43 (27%), Positives = 23/43 (53%)
Query: 75 GNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGE 117
GN+I P ++ P F + S+ ++ G P+ LG ++G+
Sbjct: 34 GNVIFSPKSSFPLPRAFIPVGSNFQPKTSSHGFPVTLGGAQGQ 76
>gi|194248077 Kruppel-like factor 4 (gut) [Homo sapiens]
Length = 479
Score = 28.9 bits (63), Expect = 3.5
Identities = 13/25 (52%), Positives = 18/25 (72%)
Query: 92 FALASSLSSASAEKGSPILLGVSKG 116
F L +SLS+ +E GSP ++ VSKG
Sbjct: 229 FVLKASLSAPGSEYGSPSVISVSKG 253
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,579,662
Number of Sequences: 37866
Number of extensions: 464549
Number of successful extensions: 1316
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1245
Number of HSP's gapped (non-prelim): 57
length of query: 218
length of database: 18,247,518
effective HSP length: 98
effective length of query: 120
effective length of database: 14,536,650
effective search space: 1744398000
effective search space used: 1744398000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.