Guide to the Human Genome
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Search of human proteins with 20070302

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|20070302 docking protein 4 [Homo sapiens]
         (326 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|20070302 docking protein 4 [Homo sapiens]                          672   0.0  
gi|47575849 docking protein 6 [Homo sapiens]                          427   e-120
gi|29544726 docking protein 5 [Homo sapiens]                          372   e-103
gi|4503357 docking protein 1 [Homo sapiens]                            70   3e-12
gi|41406050 docking protein 2 [Homo sapiens]                           64   1e-10
gi|5730059 fibroblast growth factor receptor substrate 3 [Homo s...    56   5e-08
gi|221554537 docking protein 3 isoform 1 [Homo sapiens]                51   2e-06
gi|5031805 insulin receptor substrate 1 [Homo sapiens]                 50   3e-06
gi|110347414 fibroblast growth factor receptor substrate 2 [Homo...    50   4e-06
gi|110347408 fibroblast growth factor receptor substrate 2 [Homo...    50   4e-06
gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens]            41   0.001
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 40   0.002
gi|156938343 talin 2 [Homo sapiens]                                    37   0.031
gi|223029410 talin 1 [Homo sapiens]                                    35   0.091
gi|22003858 ventricular zone expressed PH domain homolog 1 [Homo...    33   0.45 
gi|93102364 SWAP-70 protein [Homo sapiens]                             32   1.0  
gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [H...    31   1.3  
gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [H...    31   1.3  
gi|31077211 hypoxia-inducible factor 1, alpha subunit isoform 2 ...    30   2.2  
gi|4504385 hypoxia-inducible factor 1, alpha subunit isoform 1 [...    30   2.2  
gi|20270253 activating signal cointegrator 1 complex subunit 2 [...    29   5.0  
gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]       29   6.5  
gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]       29   6.5  
gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]       29   6.5  
gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]        29   6.5  
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]         29   6.5  
gi|4502023 AKT2 kinase [Homo sapiens]                                  28   8.5  
gi|18252045 ADAM metallopeptidase domain 33 isoform alpha prepro...    28   8.5  
gi|24041040 ADAM metallopeptidase domain 33 isoform beta preprop...    28   8.5  
gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precurso...    28   8.5  

>gi|20070302 docking protein 4 [Homo sapiens]
          Length = 326

 Score =  672 bits (1735), Expect = 0.0
 Identities = 326/326 (100%), Positives = 326/326 (100%)

Query: 1   MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVT 60
           MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVT
Sbjct: 1   MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVT 60

Query: 61  EISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDIS 120
           EISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDIS
Sbjct: 61  EISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDIS 120

Query: 121 LGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWP 180
           LGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWP
Sbjct: 121 LGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWP 180

Query: 181 LCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLE 240
           LCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLE
Sbjct: 181 LCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLE 240

Query: 241 MEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHITGSQNIAEASSYAGEGYGAAQASSET 300
           MEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHITGSQNIAEASSYAGEGYGAAQASSET
Sbjct: 241 MEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHITGSQNIAEASSYAGEGYGAAQASSET 300

Query: 301 DLLNRFILLKPKPSQGDSSEAKTPSQ 326
           DLLNRFILLKPKPSQGDSSEAKTPSQ
Sbjct: 301 DLLNRFILLKPKPSQGDSSEAKTPSQ 326


>gi|47575849 docking protein 6 [Homo sapiens]
          Length = 331

 Score =  427 bits (1098), Expect = e-120
 Identities = 202/297 (68%), Positives = 248/297 (83%), Gaps = 2/297 (0%)

Query: 1   MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVT 60
           MA+NF+DIVKQGYVK++SRKLGI+RRCWLVF+K+SSKGP+RLEK+PDEK+   R   KVT
Sbjct: 1   MASNFNDIVKQGYVKIRSRKLGIFRRCWLVFKKASSKGPRRLEKFPDEKAAYFRNFHKVT 60

Query: 61  EISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDIS 120
           E+ N+K +TRLP+ETK+ AVAIIF D++++TF C+SELEAEEW K L +ECLG+RLNDIS
Sbjct: 61  ELHNIKNITRLPRETKKHAVAIIFHDETSKTFACESELEAEEWCKHLCMECLGTRLNDIS 120

Query: 121 LGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWP 180
           LGEPDLLA GVQ EQ +RFNV+L+P PNLD+YGEC +QITHENIYLWDIHN +VKLV WP
Sbjct: 121 LGEPDLLAAGVQREQNERFNVYLMPTPNLDIYGECTMQITHENIYLWDIHNAKVKLVMWP 180

Query: 181 LCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLE 240
           L SLRRYGRD+T FTFE+GRMCD GEGL+TFQT+EGE IYQ+VHSATLAIAEQH+R++LE
Sbjct: 181 LSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQKVHSATLAIAEQHERLMLE 240

Query: 241 MEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHITGSQNIAEASSYAGEGYGAAQAS 297
           ME+  RL    TE  +   + +  LPRSAYWHHIT   ++ E  S  G G+G+++ S
Sbjct: 241 MEQKARLQTSLTEPMT--LSKSISLPRSAYWHHITRQNSVGEIYSLQGHGFGSSKMS 295


>gi|29544726 docking protein 5 [Homo sapiens]
          Length = 306

 Score =  372 bits (956), Expect = e-103
 Identities = 179/275 (65%), Positives = 225/275 (81%), Gaps = 2/275 (0%)

Query: 1   MATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVT 60
           MA+NF+DIVKQGYV+++SR+LGIY+RCWLVF+K+SSKGP+RLEK+ DE++   R   KVT
Sbjct: 1   MASNFNDIVKQGYVRIRSRRLGIYQRCWLVFKKASSKGPKRLEKFSDERAAYFRCYHKVT 60

Query: 61  EISNVKCVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDIS 120
           E++NVK V RLPK TK+ A+ I F DD+++TF C+S+LEA+EW K L +EC+G+R+NDIS
Sbjct: 61  ELNNVKNVARLPKSTKKHAIGIYFNDDTSKTFACESDLEADEWCKVLQMECVGTRINDIS 120

Query: 121 LGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWP 180
           LGEPDLLA GV+ EQ++RFNV+L+P PNLDV+GEC LQIT+E I LWD+ NPRVKL+SWP
Sbjct: 121 LGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWP 180

Query: 181 LCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLE 240
           L +LRRYGRD T FTFEAGRMC+ GEGL+ FQT++GE IYQ+VHSA LAIAEQH+R LL+
Sbjct: 181 LSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHER-LLQ 239

Query: 241 MEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHIT 275
             KN  L  K +E  +   T    LPRSAYW HIT
Sbjct: 240 SVKNSMLQMKMSERAASLST-MVPLPRSAYWQHIT 273


>gi|4503357 docking protein 1 [Homo sapiens]
          Length = 481

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 69/246 (28%), Positives = 107/246 (43%), Gaps = 30/246 (12%)

Query: 9   VKQGYVKMKSRKLGI--YRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRG--------CPK 58
           V +G + ++S++ G   +R+ W V   +S  G  RLE +  + S    G        C K
Sbjct: 5   VMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRLDC-K 63

Query: 59  VTEISNVKCVTRLPKETKRQAVAIIFTDDSART---FTCDSELEAEEWYKTLSVECL--G 113
           V  ++    V  +  ET  +  A  F  D+A+       D+   A  W +TL       G
Sbjct: 64  VIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAA-WVQTLCRNAFPKG 122

Query: 114 S----------RLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHEN 163
           S          +L+ + + E  L +P  +  Q               ++G   L++  E 
Sbjct: 123 SWTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEAER 182

Query: 164 IYLWDIHNPRV---KLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIY 220
           + L  +         L+SWP   LRRYGRD   F+FEAGR C +G G +TFQT +G  I+
Sbjct: 183 LTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIF 242

Query: 221 QRVHSA 226
           Q V +A
Sbjct: 243 QAVETA 248


>gi|41406050 docking protein 2 [Homo sapiens]
          Length = 412

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 57/242 (23%), Positives = 102/242 (42%), Gaps = 24/242 (9%)

Query: 9   VKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQ------RLEKYPDEKSVCLRGCPKVTEI 62
           VKQG++ ++ ++   + + W  F  S   G         L++ P++   C     KV  +
Sbjct: 6   VKQGFLYLQQQQT--FGKKWRRFGASLYGGSDCALARLELQEGPEKPRRC-EAARKVIRL 62

Query: 63  SNVKCVTRLPKETKR-QAVAIIFTDDSARTFTCDSEL-EAEEWYKTLSVECLGSRLNDIS 120
           S+   V     E    +  +  F +   R +   +   E  +W + + +     +  ++S
Sbjct: 63  SDCLRVAEAGGEASSPRDTSAFFLETKERLYLLAAPAAERGDWVQAICLLAFPGQRKELS 122

Query: 121 ----------LGEPDLLAPGVQCEQTDRFNVFLLPCPNLD---VYGECKLQITHENIYLW 167
                     + E +L +  V       F V + P    +   + G   L+     + LW
Sbjct: 123 GPEGKQSRPCMEENELYSSAVTVGPHKEFAVTMRPTEASERCHLRGSYTLRAGESALELW 182

Query: 168 DIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSAT 227
               P  +L  WP   LRR+GRD   F+FEAGR C +GEG + F+T++G +I+  +  A 
Sbjct: 183 GGPEPGTQLYDWPYRFLRRFGRDKVTFSFEAGRRCVSGEGNFEFETRQGNEIFLALEEAI 242

Query: 228 LA 229
            A
Sbjct: 243 SA 244


>gi|5730059 fibroblast growth factor receptor substrate 3 [Homo
           sapiens]
          Length = 492

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 25/68 (36%), Positives = 39/68 (57%), Gaps = 3/68 (4%)

Query: 153 GECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQ 212
           G   +++T   + L   H  R + V WP   LRRYG D+  F+FE+GR C  G+G++ F+
Sbjct: 34  GSGVMELTQSELVL---HLHRREAVRWPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFK 90

Query: 213 TQEGEQIY 220
               E+I+
Sbjct: 91  CSRAEEIF 98


>gi|221554537 docking protein 3 isoform 1 [Homo sapiens]
          Length = 496

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 27/62 (43%), Positives = 36/62 (58%), Gaps = 3/62 (4%)

Query: 176 LVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHK 235
           L SWP   LR++G D   F+FEAGR C +GEGL+ F T     + + V     AIA Q +
Sbjct: 256 LYSWPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFSTPCAPDLCRAVAG---AIARQRE 312

Query: 236 RV 237
           R+
Sbjct: 313 RL 314


>gi|5031805 insulin receptor substrate 1 [Homo sapiens]
          Length = 1242

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 58/255 (22%), Positives = 98/255 (38%), Gaps = 41/255 (16%)

Query: 5   FSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISN 64
           FSD+ K GY++   +   +++R +++   S + GP RLE Y +EK    +       I  
Sbjct: 10  FSDVRKVGYLR---KPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPL 66

Query: 65  VKCVTRLPK-ETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTL---------------- 107
             C     + ++K + +  ++T D       DSE E + WY+ L                
Sbjct: 67  ESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGHHDGAAA 126

Query: 108 -----------SVECLGSRLNDISLGEPDLLAPGVQCEQTDRFNVFLLP---CPNLDVYG 153
                          LG    D+S G+   + PG   ++   + V L P       ++ G
Sbjct: 127 LGAGGGGGSCSGSSGLGEAGEDLSYGD---VPPGPAFKEV--WQVILKPKGLGQTKNLIG 181

Query: 154 ECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQT 213
             +L +T + I    + N     V   L ++RR G     F  E GR    G G +  Q 
Sbjct: 182 IYRLCLTSKTISFVKL-NSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV 240

Query: 214 QEGEQIYQRVHSATL 228
            +   + Q +H   L
Sbjct: 241 DD-SVVAQNMHETIL 254


>gi|110347414 fibroblast growth factor receptor substrate 2 [Homo
           sapiens]
          Length = 508

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)

Query: 177 VSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKR 236
           V W    LRRYG D+  F+FE+GR C  G+G++ F+    E+++  +         Q+  
Sbjct: 55  VKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIM-----QNNS 109

Query: 237 VLLEMEKNVRLLNKGTEHYSYPCTPTT 263
           + +  E  V   N  TE    P TP T
Sbjct: 110 INVVEEPVVERNNHQTE-LEVPRTPRT 135


>gi|110347408 fibroblast growth factor receptor substrate 2 [Homo
           sapiens]
          Length = 508

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 6/87 (6%)

Query: 177 VSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKR 236
           V W    LRRYG D+  F+FE+GR C  G+G++ F+    E+++  +         Q+  
Sbjct: 55  VKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIM-----QNNS 109

Query: 237 VLLEMEKNVRLLNKGTEHYSYPCTPTT 263
           + +  E  V   N  TE    P TP T
Sbjct: 110 INVVEEPVVERNNHQTE-LEVPRTPRT 135


>gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens]
          Length = 504

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 28/85 (32%), Positives = 40/85 (47%), Gaps = 2/85 (2%)

Query: 135 QTDRFNVFLLPCPNLDVYGECKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRF 194
           +  RF+V + P   L+  G   L + ++ + L     P V    W L  LRRYG   + F
Sbjct: 110 EVHRFHVTVAPGTKLES-GPATLHLCNDVLVLARDIPPAVT-GQWKLSDLRRYGAVPSGF 167

Query: 195 TFEAGRMCDAGEGLYTFQTQEGEQI 219
            FE G  C    G++   + EGEQI
Sbjct: 168 IFEGGTRCGYWAGVFFLSSAEGEQI 192


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 57/241 (23%), Positives = 88/241 (36%), Gaps = 37/241 (15%)

Query: 7   DIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEK----SVCLRGCPKVTEI 62
           ++ K+GY  ++ +K G   R + V +  ++  P RLE Y + +    SV           
Sbjct: 78  EVCKRGY--LRKQKHG--HRRYFVLKLETADAPARLEYYENARKFRHSVRAAAAAAAAAA 133

Query: 63  SNVKCVTRLPK----------------ETKRQAVAIIFTDDSARTFTCDSELEAEEWYKT 106
           S       +P                 + + + +  +FT D       ++E E E WY  
Sbjct: 134 SGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLL 193

Query: 107 LSVECLGSR------LNDISLGEPDLLAPGVQCE---QTDRFNVFLLP---CPNLDVYGE 154
           LS   L S+      L     GEP  LA     E     D + V + P       ++ G 
Sbjct: 194 LSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVKPRGLGHRKELSGV 253

Query: 155 CKLQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQ 214
            +L +T E +    + N  V  V   L S+RR G     F  E GR    G G    Q  
Sbjct: 254 FRLCLTDEEVVFVRL-NTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWMQVD 312

Query: 215 E 215
           +
Sbjct: 313 D 313


>gi|156938343 talin 2 [Homo sapiens]
          Length = 2542

 Score = 36.6 bits (83), Expect = 0.031
 Identities = 23/67 (34%), Positives = 34/67 (50%), Gaps = 4/67 (5%)

Query: 157 LQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEG 216
           L IT +++   D     V L  WPL +++R+      FT + G   +  E  Y+ QT EG
Sbjct: 333 LGITKDSVMRVDEKTKEV-LQEWPLTTVKRWAASPKSFTLDFG---EYQESYYSVQTTEG 388

Query: 217 EQIYQRV 223
           EQI Q +
Sbjct: 389 EQISQLI 395


>gi|223029410 talin 1 [Homo sapiens]
          Length = 2541

 Score = 35.0 bits (79), Expect = 0.091
 Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 4/67 (5%)

Query: 157 LQITHENIYLWDIHNPRVKLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEG 216
           L IT E +   D     V +  W L +++R+      FT + G   D  +G Y+ QT EG
Sbjct: 330 LGITKECVMRVDEKTKEV-IQEWNLTNIKRWAASPKSFTLDFG---DYQDGYYSVQTTEG 385

Query: 217 EQIYQRV 223
           EQI Q +
Sbjct: 386 EQIAQLI 392


>gi|22003858 ventricular zone expressed PH domain homolog 1 [Homo
           sapiens]
          Length = 833

 Score = 32.7 bits (73), Expect = 0.45
 Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 14/82 (17%)

Query: 29  LVFRKSSSKGPQRLEKYPDEKSVCLRGCP-KVTEISNVKCVTRLPKETKRQAVAIIFTDD 87
           L+F+K  SK        PD+       CP +++++ +VK V +  ++        IFTD+
Sbjct: 748 LLFQKGKSKDD------PDD-------CPIELSKVQSVKAVAKKRRDRSLPRAFEIFTDN 794

Query: 88  SARTFTCDSELEAEEWYKTLSV 109
               F    E  A EW + ++V
Sbjct: 795 KTYVFKAKDEKNAAEWLQCINV 816


>gi|93102364 SWAP-70 protein [Homo sapiens]
          Length = 585

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 24/118 (20%), Positives = 49/118 (41%), Gaps = 14/118 (11%)

Query: 7   DIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEISNVK 66
           D++KQGY+  K  +   +   W V +      P  +  Y  E     +G   + E     
Sbjct: 210 DVLKQGYMMKKGHRRKNWTERWFVLK------PNIISYYVSEDLKDKKGDILLDENC--- 260

Query: 67  CVTRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSVECLGSRLNDISLGEP 124
           CV  LP +  ++ + ++   D     +   + + +EW     ++ + S ++ + LG P
Sbjct: 261 CVESLPDKDGKKCLFLVKCFDKTFEISASDKKKKQEW-----IQAIHSTIHLLKLGSP 313


>gi|115527076 src kinase associated phosphoprotein 1 isoform 2 [Homo
           sapiens]
          Length = 358

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 4/108 (3%)

Query: 2   ATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTE 61
           A    +++KQGY++ KS+    +   W       S+G      Y +EKS   +G   +  
Sbjct: 102 AQELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRG--LFYYYANEKSKQPKGTFLIKG 159

Query: 62  ISNVKCVTRLPKETKRQAVAIIFTDD-SARTFTCDSELEAEEWYKTLS 108
              V+    L +++K+++   + + D  +  FT  S  EA +W   +S
Sbjct: 160 Y-GVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQIS 206


>gi|115527074 src kinase associated phosphoprotein 1 isoform 1 [Homo
           sapiens]
          Length = 359

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 4/108 (3%)

Query: 2   ATNFSDIVKQGYVKMKSRKLGIYRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTE 61
           A    +++KQGY++ KS+    +   W       S+G      Y +EKS   +G   +  
Sbjct: 102 AQELDNVIKQGYLEKKSKDHSFFGSEWQKRWCVVSRG--LFYYYANEKSKQPKGTFLIKG 159

Query: 62  ISNVKCVTRLPKETKRQAVAIIFTDD-SARTFTCDSELEAEEWYKTLS 108
              V+    L +++K+++   + + D  +  FT  S  EA +W   +S
Sbjct: 160 Y-GVRMAPHLRRDSKKESCFELTSQDRRSYEFTATSPAEARDWVDQIS 206


>gi|31077211 hypoxia-inducible factor 1, alpha subunit isoform 2
           [Homo sapiens]
          Length = 735

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 22/91 (24%), Positives = 38/91 (41%), Gaps = 2/91 (2%)

Query: 59  VTEISNVKCVTRLPKETKRQAVAIIFTD-DSARTFTCDSELEAEEWYKTLSVECLGSRLN 117
           +  +   +CV + P E+    +  +FT  +S  T +   +L+ E    TL     G  + 
Sbjct: 351 IFSLQQTECVLK-PVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTII 409

Query: 118 DISLGEPDLLAPGVQCEQTDRFNVFLLPCPN 148
            +  G  D      Q E+   +N  +LP PN
Sbjct: 410 SLDFGSNDTETDDQQLEEVPLYNDVMLPSPN 440


>gi|4504385 hypoxia-inducible factor 1, alpha subunit isoform 1
           [Homo sapiens]
          Length = 826

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 22/91 (24%), Positives = 38/91 (41%), Gaps = 2/91 (2%)

Query: 59  VTEISNVKCVTRLPKETKRQAVAIIFTD-DSARTFTCDSELEAEEWYKTLSVECLGSRLN 117
           +  +   +CV + P E+    +  +FT  +S  T +   +L+ E    TL     G  + 
Sbjct: 351 IFSLQQTECVLK-PVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTII 409

Query: 118 DISLGEPDLLAPGVQCEQTDRFNVFLLPCPN 148
            +  G  D      Q E+   +N  +LP PN
Sbjct: 410 SLDFGSNDTETDDQQLEEVPLYNDVMLPSPN 440


>gi|20270253 activating signal cointegrator 1 complex subunit 2
           [Homo sapiens]
          Length = 757

 Score = 29.3 bits (64), Expect = 5.0
 Identities = 21/84 (25%), Positives = 37/84 (44%), Gaps = 1/84 (1%)

Query: 222 RVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHYSYPCTPTTMLPRSAYWHHITGSQNIA 281
           RVH       E++ R LL  ++ V    +  E YS       + P  +  +H    ++  
Sbjct: 557 RVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEY 616

Query: 282 EASSYAGEGYGAAQASSETDLLNR 305
           +  +Y G   GA  A S+ +L++R
Sbjct: 617 D-DTYDGNQVGANDADSDDELISR 639


>gi|194239709 dedicator of cytokinesis 9 isoform d [Homo sapiens]
          Length = 1253

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 17/78 (21%)

Query: 38  GPQRLEKYPDEK-------SVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSAR 90
           G   L  Y DEK       S+ L  C  V + + V+   R   E K Q       D S+ 
Sbjct: 209 GSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVR---RFAFELKMQ-------DKSSY 258

Query: 91  TFTCDSELEAEEWYKTLS 108
               DSE+E EEW   L+
Sbjct: 259 LLAADSEVEMEEWITILN 276


>gi|194239707 dedicator of cytokinesis 9 isoform c [Homo sapiens]
          Length = 1254

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 17/78 (21%)

Query: 38  GPQRLEKYPDEK-------SVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSAR 90
           G   L  Y DEK       S+ L  C  V + + V+   R   E K Q       D S+ 
Sbjct: 210 GSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVR---RFAFELKMQ-------DKSSY 259

Query: 91  TFTCDSELEAEEWYKTLS 108
               DSE+E EEW   L+
Sbjct: 260 LLAADSEVEMEEWITILN 277


>gi|194239705 dedicator of cytokinesis 9 isoform b [Homo sapiens]
          Length = 2068

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 17/78 (21%)

Query: 38  GPQRLEKYPDEK-------SVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSAR 90
           G   L  Y DEK       S+ L  C  V + + V+   R   E K Q       D S+ 
Sbjct: 209 GSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVR---RFAFELKMQ-------DKSSY 258

Query: 91  TFTCDSELEAEEWYKTLS 108
               DSE+E EEW   L+
Sbjct: 259 LLAADSEVEMEEWITILN 276


>gi|24308029 dedicator of cytokinesis 9 isoform a [Homo sapiens]
          Length = 2069

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 17/78 (21%)

Query: 38  GPQRLEKYPDEK-------SVCLRGCPKVTEISNVKCVTRLPKETKRQAVAIIFTDDSAR 90
           G   L  Y DEK       S+ L  C  V + + V+   R   E K Q       D S+ 
Sbjct: 210 GSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVR---RFAFELKMQ-------DKSSY 259

Query: 91  TFTCDSELEAEEWYKTLS 108
               DSE+E EEW   L+
Sbjct: 260 LLAADSEVEMEEWITILN 277


>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
          Length = 1303

 Score = 28.9 bits (63), Expect = 6.5
 Identities = 22/80 (27%), Positives = 32/80 (40%), Gaps = 13/80 (16%)

Query: 254 HYSYPCTPTTMLPRSAYWHHITGSQNIAEASSYAGEGYGAAQASSETDL----------- 302
           H  YP +  T LP+ AY    + S  + E   Y  E YG  +   E D+           
Sbjct: 166 HQQYPPSHATPLPKKAYSKMDSKSYGMYE--DYENEQYGEYEGDEEEDMGKEDYDDFTKE 223

Query: 303 LNRFILLKPKPSQGDSSEAK 322
           LN++   K   S+G  S  +
Sbjct: 224 LNQYRRAKEGSSRGRGSRGR 243


>gi|4502023 AKT2 kinase [Homo sapiens]
          Length = 481

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 25/110 (22%), Positives = 46/110 (41%), Gaps = 10/110 (9%)

Query: 4   NFSDIVKQGYVKMKSRKLGIYR-RCWLVFRKSSSKGPQRLEKYPDEKSVCLRGCPKVTEI 62
           N   ++K+G++  +   +  +R R +L+    S  G +   + PD+        P +   
Sbjct: 2   NEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQT------LPPLNNF 55

Query: 63  SNVKCV---TRLPKETKRQAVAIIFTDDSARTFTCDSELEAEEWYKTLSV 109
           S  +C    T  P+        + +T    RTF  DS  E EEW + + +
Sbjct: 56  SVAECQLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWMRAIQM 105


>gi|18252045 ADAM metallopeptidase domain 33 isoform alpha
           preproprotein [Homo sapiens]
          Length = 813

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 211 FQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKG--TEHYSYPCTPTTMLPRS 268
           ++T   E+   +     +A+  + + +LLE+EKN RLL  G    HY     P  + P  
Sbjct: 51  WRTVSLEEPVSKPDMGLVALEAEGQELLLELEKNHRLLAPGYIETHYGPDGQPVVLAPNH 110

Query: 269 AYWHHITG 276
               H  G
Sbjct: 111 TDHCHYQG 118


>gi|24041040 ADAM metallopeptidase domain 33 isoform beta
           preproprotein [Homo sapiens]
          Length = 787

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 2/68 (2%)

Query: 211 FQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKG--TEHYSYPCTPTTMLPRS 268
           ++T   E+   +     +A+  + + +LLE+EKN RLL  G    HY     P  + P  
Sbjct: 51  WRTVSLEEPVSKPDMGLVALEAEGQELLLELEKNHRLLAPGYIETHYGPDGQPVVLAPNH 110

Query: 269 AYWHHITG 276
               H  G
Sbjct: 111 TDHCHYQG 118


>gi|4503899 galactosamine (N-acetyl)-6-sulfate sulfatase precursor
           [Homo sapiens]
          Length = 522

 Score = 28.5 bits (62), Expect = 8.5
 Identities = 20/86 (23%), Positives = 33/86 (38%), Gaps = 13/86 (15%)

Query: 196 FEAGRMCDAGEGLYTFQTQEGEQIYQRVHSATLAIAEQHKRVLLEMEKNVRLLNKGTEHY 255
           F  GR  D GE    F        YQ   S   ++ +QH+  L+  +  + + N    ++
Sbjct: 442 FHLGR--DPGE---RFPLSFASAEYQEALSRITSVVQQHQEALVPAQPQLNVCNWAVMNW 496

Query: 256 SYP--------CTPTTMLPRSAYWHH 273
           + P         TP   +P+   W H
Sbjct: 497 APPGCEKLGKCLTPPESIPKKCLWSH 522


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,684,948
Number of Sequences: 37866
Number of extensions: 549695
Number of successful extensions: 1229
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1209
Number of HSP's gapped (non-prelim): 32
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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