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Search of human proteins with 20070262
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20070262 TNF receptor-associated factor 3 interacting
protein 1 isoform 1 [Homo sapiens]
(691 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20070262 TNF receptor-associated factor 3 interacting protein... 1353 0.0
gi|213385278 TNF receptor-associated factor 3 interacting protei... 1070 0.0
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 116 8e-26
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 116 8e-26
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 111 3e-24
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 108 2e-23
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 103 5e-22
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 103 5e-22
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 102 2e-21
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 101 2e-21
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 98 2e-20
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 96 1e-19
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 93 7e-19
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 90 6e-18
gi|52426743 cisplatin resistance-associated overexpressed protei... 89 1e-17
gi|19923485 cisplatin resistance-associated overexpressed protei... 89 1e-17
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 89 1e-17
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 89 2e-17
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 83 1e-15
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 82 1e-15
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 81 3e-15
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 79 1e-14
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 79 1e-14
gi|34878777 ring finger protein 20 [Homo sapiens] 79 2e-14
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 77 7e-14
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 76 1e-13
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 75 2e-13
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 74 3e-13
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 74 5e-13
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 74 5e-13
>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
isoform 1 [Homo sapiens]
Length = 691
Score = 1353 bits (3503), Expect = 0.0
Identities = 691/691 (100%), Positives = 691/691 (100%)
Query: 1 MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS 60
MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS
Sbjct: 1 MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS 60
Query: 61 DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS 120
DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS
Sbjct: 61 DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS 120
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR
Sbjct: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
Query: 181 DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD 240
DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD
Sbjct: 181 DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD 240
Query: 241 RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD 300
RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD
Sbjct: 241 RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD 300
Query: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDN 360
KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDN
Sbjct: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDN 360
Query: 361 ISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQK 420
ISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQK
Sbjct: 361 ISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQK 420
Query: 421 GDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEAL 480
GDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEAL
Sbjct: 421 GDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEAL 480
Query: 481 QMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGL 540
QMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGL
Sbjct: 481 QMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGL 540
Query: 541 VKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL 600
VKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL
Sbjct: 541 VKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL 600
Query: 601 GKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQ 660
GKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQ
Sbjct: 601 GKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQ 660
Query: 661 QDKICAVKANILKNEEKIQKMVYSINLTSRR 691
QDKICAVKANILKNEEKIQKMVYSINLTSRR
Sbjct: 661 QDKICAVKANILKNEEKIQKMVYSINLTSRR 691
>gi|213385278 TNF receptor-associated factor 3 interacting protein 1
isoform 2 [Homo sapiens]
Length = 625
Score = 1070 bits (2767), Expect = 0.0
Identities = 577/691 (83%), Positives = 591/691 (85%), Gaps = 66/691 (9%)
Query: 1 MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS 60
MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS
Sbjct: 1 MNAAVVRRTQEALGKVIRRPPLTEKLLSKPPFRYLHDIITEVIRMTGFMKGLYTDAEMKS 60
Query: 61 DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS 120
DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS
Sbjct: 61 DNVKDKDAKISFLQKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLS 120
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR
Sbjct: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
Query: 181 DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD 240
DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD
Sbjct: 181 DRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERD 240
Query: 241 RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD 300
RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD
Sbjct: 241 RDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD 300
Query: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDN 360
KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEG D+
Sbjct: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEG---DS 357
Query: 361 ISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQK 420
S D+ +G + ET I ++ S+++R P P
Sbjct: 358 TSDAEGDAGPAGQDKSEVPET--------------PEIPNELSSNIR---RIPRP----- 395
Query: 421 GDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEAL 480
G A PA P + + S ++ R GS +
Sbjct: 396 --------GSARPA---------PPRVKRQDSMEALQMDRSGSGK--------------- 423
Query: 481 QMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGL 540
TVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGL
Sbjct: 424 ---------TVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGL 474
Query: 541 VKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL 600
VKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL
Sbjct: 475 VKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPL 534
Query: 601 GKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQ 660
GKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQ
Sbjct: 535 GKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQ 594
Query: 661 QDKICAVKANILKNEEKIQKMVYSINLTSRR 691
QDKICAVKANILKNEEKIQKMVYSINLTSRR
Sbjct: 595 QDKICAVKANILKNEEKIQKMVYSINLTSRR 625
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 116 bits (290), Expect = 8e-26
Identities = 92/331 (27%), Positives = 163/331 (49%), Gaps = 26/331 (7%)
Query: 130 AGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELK 189
+G+ E KG S S ++ + + R ++ R + + RS +DR++ K
Sbjct: 297 SGKSNERKGGRS-RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS---K 352
Query: 190 EDRKPREKDKDKEKAKENGGNRH-REGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
K R K +++ K++ +R R+ RE+ K + R ++KDR +ER+R+ ER+KE
Sbjct: 353 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV---KEKDR-EKEREREKEREKE 408
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
ER GK K+ RD++RE+DR+K K++DR R + EH D D+EK +E DK +++
Sbjct: 409 KER----GKNKD--RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK- 461
Query: 309 SGEMSKKLSDGTFKDSKAET--ETEISTRASKSLTTKTSKRRSKNSVEG-RKEDNISAKS 365
+ SK++ + KD K+ T + ++R S+S + + +RRS++S R I KS
Sbjct: 462 --DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 519
Query: 366 LDSIVSGINN--EPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDS 423
S N + +E I + STS+ ++ E ++ N T ++ +
Sbjct: 520 SRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 579
Query: 424 TSDAEGDAGPAGQDKSEVPETPEIPNELSSN 454
+ + DK + P T E N++ N
Sbjct: 580 NKEPDSSVSKEVDDK-DAPRTEE--NKIQHN 607
Score = 96.3 bits (238), Expect = 9e-20
Identities = 83/366 (22%), Positives = 146/366 (39%), Gaps = 84/366 (22%)
Query: 152 KNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNR 211
K+ + R +T + + K S + + K + + R + KD+ ++K R
Sbjct: 299 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 358
Query: 212 HREGERERAKARARPDNERQKDRGN-------RERDRDSERKKETERKSEGGKEKERLRD 264
+ ER ++++R+ ++R+ R +E+DR+ ER++E ER+ E + K + RD
Sbjct: 359 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 418
Query: 265 RDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
++RE+DR+K K++DR R + EH D D+EK +E DK +++ + SK++ + KD
Sbjct: 419 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK---DRSKEIDEKRKKDK 475
Query: 325 KAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTS 384
K+ T S AS+ + + +RR R+ S++S T+
Sbjct: 476 KSRTPPR-SYNASRRSRSSSRERR-------RRRSRSSSRS--------------PRTSK 513
Query: 385 EIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPET 444
I K + P+P + K D + E D
Sbjct: 514 TIKRKSSR-------------------SPSPRSRNKKDKKREKERD-------------- 540
Query: 445 PEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNE 504
+S R +R SM DR G K N + N+
Sbjct: 541 -----HISERRER--------------ERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK 581
Query: 505 EDDQFV 510
E D V
Sbjct: 582 EPDSSV 587
Score = 87.8 bits (216), Expect = 3e-17
Identities = 65/261 (24%), Positives = 113/261 (43%), Gaps = 37/261 (14%)
Query: 137 KGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR-----KQKEELKED 191
K R+ SR + D + +E+ RV + ++ KER ++R + KE K+
Sbjct: 366 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 425
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNR-ERDRDSERKKETE 250
K +EKD+++E+ KE+ +R +E E+E+ K + ER+KDR + R ++K T
Sbjct: 426 EKDKEKDREREREKEHEKDRDKEKEKEQDK-----EKEREKDRSKEIDEKRKKDKKSRTP 480
Query: 251 RKSEGGKEKERLRDRDRERDRDKGKDRDRRRVK------------NGEHSWDLDREKNRE 298
+S + R R+R R R + R R K + D REK R+
Sbjct: 481 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 540
Query: 299 HDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTR---------ASKSLTTKTSKRRS 349
H ++ S M K +D K+ + T + + SK + K + R
Sbjct: 541 HISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 600
Query: 350 KNSVEGR-----KEDNISAKS 365
+N ++ E+N+S K+
Sbjct: 601 ENKIQHNGNCQLNEENLSTKT 621
Score = 34.7 bits (78), Expect = 0.30
Identities = 42/184 (22%), Positives = 76/184 (41%), Gaps = 15/184 (8%)
Query: 403 SASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPG 462
SA++ E+ + N E++ G S S + + + S + S N R +
Sbjct: 290 SAAIEPESGKSN--ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKD 347
Query: 463 SARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMS- 521
R P KR S E + RS SH+ D +D + ++ ++ E
Sbjct: 348 RRRSKSPHKKRSKSRER-RKSRS-----------RSHSRDKRKDTREKIKEKERVKEKDR 395
Query: 522 EIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSK 581
E E E E+E++ G + E +KD EK ++ + E+E+ + K+++ K
Sbjct: 396 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 455
Query: 582 EIEK 585
E E+
Sbjct: 456 EKER 459
Score = 33.1 bits (74), Expect = 0.88
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 13/130 (10%)
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRV----HKNTEDRGDAEIKER 176
S +A RR + + + R+ +SRS +K ++ + SR +N +D+ KER
Sbjct: 483 SYNASRRSRSSSRERRRRRSRSSSRSPR-TSKTIKRKSSRSPSPRSRNKKDK--KREKER 539
Query: 177 STSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGN 236
+R+++E RK KEK ++N + E+E K PD+ K+ +
Sbjct: 540 DHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLK---EKEHNK---EPDSSVSKEVDD 593
Query: 237 RERDRDSERK 246
++ R E K
Sbjct: 594 KDAPRTEENK 603
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 116 bits (290), Expect = 8e-26
Identities = 92/331 (27%), Positives = 163/331 (49%), Gaps = 26/331 (7%)
Query: 130 AGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELK 189
+G+ E KG S S ++ + + R ++ R + + RS +DR++ K
Sbjct: 181 SGKSNERKGGRS-RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRS---K 236
Query: 190 EDRKPREKDKDKEKAKENGGNRH-REGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
K R K +++ K++ +R R+ RE+ K + R ++KDR +ER+R+ ER+KE
Sbjct: 237 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV---KEKDR-EKEREREKEREKE 292
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
ER GK K+ RD++RE+DR+K K++DR R + EH D D+EK +E DK +++
Sbjct: 293 KER----GKNKD--RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK- 345
Query: 309 SGEMSKKLSDGTFKDSKAET--ETEISTRASKSLTTKTSKRRSKNSVEG-RKEDNISAKS 365
+ SK++ + KD K+ T + ++R S+S + + +RRS++S R I KS
Sbjct: 346 --DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKS 403
Query: 366 LDSIVSGINN--EPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDS 423
S N + +E I + STS+ ++ E ++ N T ++ +
Sbjct: 404 SRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEH 463
Query: 424 TSDAEGDAGPAGQDKSEVPETPEIPNELSSN 454
+ + DK + P T E N++ N
Sbjct: 464 NKEPDSSVSKEVDDK-DAPRTEE--NKIQHN 491
Score = 96.3 bits (238), Expect = 9e-20
Identities = 83/366 (22%), Positives = 146/366 (39%), Gaps = 84/366 (22%)
Query: 152 KNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNR 211
K+ + R +T + + K S + + K + + R + KD+ ++K R
Sbjct: 183 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 242
Query: 212 HREGERERAKARARPDNERQKDRGN-------RERDRDSERKKETERKSEGGKEKERLRD 264
+ ER ++++R+ ++R+ R +E+DR+ ER++E ER+ E + K + RD
Sbjct: 243 SKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 302
Query: 265 RDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
++RE+DR+K K++DR R + EH D D+EK +E DK +++ + SK++ + KD
Sbjct: 303 KEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK---DRSKEIDEKRKKDK 359
Query: 325 KAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTS 384
K+ T S AS+ + + +RR R+ S++S T+
Sbjct: 360 KSRTPPR-SYNASRRSRSSSRERR-------RRRSRSSSRS--------------PRTSK 397
Query: 385 EIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPET 444
I K + P+P + K D + E D
Sbjct: 398 TIKRKSSR-------------------SPSPRSRNKKDKKREKERD-------------- 424
Query: 445 PEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNE 504
+S R +R SM DR G K N + N+
Sbjct: 425 -----HISERRER--------------ERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNK 465
Query: 505 EDDQFV 510
E D V
Sbjct: 466 EPDSSV 471
Score = 87.8 bits (216), Expect = 3e-17
Identities = 65/261 (24%), Positives = 113/261 (43%), Gaps = 37/261 (14%)
Query: 137 KGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR-----KQKEELKED 191
K R+ SR + D + +E+ RV + ++ KER ++R + KE K+
Sbjct: 250 KSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 309
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNR-ERDRDSERKKETE 250
K +EKD+++E+ KE+ +R +E E+E+ K + ER+KDR + R ++K T
Sbjct: 310 EKDKEKDREREREKEHEKDRDKEKEKEQDK-----EKEREKDRSKEIDEKRKKDKKSRTP 364
Query: 251 RKSEGGKEKERLRDRDRERDRDKGKDRDRRRVK------------NGEHSWDLDREKNRE 298
+S + R R+R R R + R R K + D REK R+
Sbjct: 365 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 424
Query: 299 HDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTR---------ASKSLTTKTSKRRS 349
H ++ S M K +D K+ + T + + SK + K + R
Sbjct: 425 HISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTE 484
Query: 350 KNSVEGR-----KEDNISAKS 365
+N ++ E+N+S K+
Sbjct: 485 ENKIQHNGNCQLNEENLSTKT 505
Score = 34.7 bits (78), Expect = 0.30
Identities = 42/184 (22%), Positives = 76/184 (41%), Gaps = 15/184 (8%)
Query: 403 SASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPG 462
SA++ E+ + N E++ G S S + + + S + S N R +
Sbjct: 174 SAAIEPESGKSN--ERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKD 231
Query: 463 SARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMS- 521
R P KR S E + RS SH+ D +D + ++ ++ E
Sbjct: 232 RRRSKSPHKKRSKSRER-RKSRS-----------RSHSRDKRKDTREKIKEKERVKEKDR 279
Query: 522 EIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSK 581
E E E E+E++ G + E +KD EK ++ + E+E+ + K+++ K
Sbjct: 280 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 339
Query: 582 EIEK 585
E E+
Sbjct: 340 EKER 343
Score = 33.1 bits (74), Expect = 0.88
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 13/130 (10%)
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRV----HKNTEDRGDAEIKER 176
S +A RR + + + R+ +SRS +K ++ + SR +N +D+ KER
Sbjct: 367 SYNASRRSRSSSRERRRRRSRSSSRSPR-TSKTIKRKSSRSPSPRSRNKKDK--KREKER 423
Query: 177 STSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGN 236
+R+++E RK KEK ++N + E+E K PD+ K+ +
Sbjct: 424 DHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLK---EKEHNK---EPDSSVSKEVDD 477
Query: 237 RERDRDSERK 246
++ R E K
Sbjct: 478 KDAPRTEENK 487
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 111 bits (277), Expect = 3e-24
Identities = 65/228 (28%), Positives = 129/228 (56%), Gaps = 11/228 (4%)
Query: 151 NKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGN 210
+K + EE+ + K +R + E + R R+R+++ E +E + RE+++++EK KE
Sbjct: 288 HKKLEEEKGKKEK---ERQEIEKERRERERERERERERREREREREREREREKEKERERE 344
Query: 211 RHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERD 270
R R+ +R+R K R R D +R++DR +R+R+R S+R K+ R E +++ER R+R+RER+
Sbjct: 345 RERDRDRDRTKERDR-DRDRERDR-DRDRERSSDRNKDRSRSREKSRDRERERERERERE 402
Query: 271 RDKGKDRDRRRVKNGEHSWDLDREKNREHDK--PEKKSASSGEMSKKLSDGTFKDSKAET 328
R++ ++R+R R + E + +REK+++ D+ E+ + ++ +KL + +
Sbjct: 403 REREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLK 462
Query: 329 ETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNE 376
EI R T+ ++ ++ E R+E AK L + +++
Sbjct: 463 NWEIRERKK----TREYEKEAEREEERRREMAKEAKRLKEFLEDYDDD 506
Score = 103 bits (258), Expect = 4e-22
Identities = 89/376 (23%), Positives = 169/376 (44%), Gaps = 26/376 (6%)
Query: 110 IIGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRG 169
+I K +N + ++ R +++ E + + T + E + +E + K +R
Sbjct: 258 LITKEDINAIEMEEDKRDLISREISKFRD----THKKLEEEKGKKEKERQEIEKERRERE 313
Query: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARP--- 226
+ER R+R+++E +E + REK+K++E+ +E +R R ER+R + R R
Sbjct: 314 ----RERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR 369
Query: 227 DNERQKDRG-NRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNG 285
D ER DR +R R R+ R +E ER+ E +E+ER R+R+RER+R++ ++R+R R K+
Sbjct: 370 DRERSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDK 429
Query: 286 EHSWDLDREKNREHDKPEKK-SASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKT 344
+ + D E E K E+K ++L + ++ K E E + +
Sbjct: 430 KRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREM 489
Query: 345 SK--RRSKNSVEGRKEDN----------ISAKSLDSIVSGINNEPNQETTTSEIGTKEAN 392
+K +R K +E +D + + D +E +++ E+
Sbjct: 490 AKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQR 549
Query: 393 INSTSISDDNSASLRCENIQPNPTEKQ-KGDSTSDAEGDAGPAGQDKSEVPETPEIPNEL 451
+ + D ++ R E + Q K + S+ E + ++K E P E E
Sbjct: 550 LLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609
Query: 452 SSNIRRIPRPGSARPA 467
++ RP S+ P+
Sbjct: 610 KPCLKPTLRPISSAPS 625
Score = 88.2 bits (217), Expect = 2e-17
Identities = 88/359 (24%), Positives = 149/359 (41%), Gaps = 83/359 (23%)
Query: 74 QKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLSSDDAVRRVL---- 129
+KA D+++ LLAK +++ + + LQ G C + S R+L
Sbjct: 96 EKASDMLI----RQLLAKCGLVLSWKRVQGASGKLQAFGFCEYKEPESTLRALRLLHDLQ 151
Query: 130 AGEKG-----EVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKER-------- 176
GEK + K +A L + N V + E+ D E K R
Sbjct: 152 IGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAI 211
Query: 177 -----------------STSRDRKQKEELKEDRKPR--------------------EKDK 199
S S RK+K+E KED R E ++
Sbjct: 212 EVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEE 271
Query: 200 DK---------------EKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSE 244
DK +K +E G + +E +E K R + ER+++R RER+R+ E
Sbjct: 272 DKRDLISREISKFRDTHKKLEEEKGKKEKE-RQEIEKERRERERERERERERRERERERE 330
Query: 245 RKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
R++E E++ E +E+ER RDRDR ++RD+ +DR+R R ++ E S D +++++R +K
Sbjct: 331 REREREKEKERERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRD 390
Query: 305 KSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISA 363
+ E ++ ++ + E E E + + + R K+ R+ED A
Sbjct: 391 RER---ERERE------REREREREREREREREREREREREREREKDKKRDREEDEEDA 440
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 108 bits (270), Expect = 2e-23
Identities = 62/242 (25%), Positives = 130/242 (53%), Gaps = 10/242 (4%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E+ K R +R + + + RE+E++ +RG +ER T + ++K + +
Sbjct: 172 ERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231
Query: 192 R-KPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKE-- 248
R + R+ ++++EK E RE ER++ + R R D +R +DR +ER+R ++RK++
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERER-DRDRDRDRRQKERERQTDRKRQRR 290
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
TER E +++ER R+R+RER+R++ ++R+R R + E + +R++ +E ++ K+
Sbjct: 291 TERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQT- 349
Query: 309 SGEMSKKLSDGTFKDSKAETETEIS---TRASKSLTTKTSKRRSKNSVEGRKEDNISAKS 365
EM ++ + T ++ + + E E R +S + + R ++ ++ + + K
Sbjct: 350 --EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Query: 366 LD 367
D
Sbjct: 408 RD 409
Score = 105 bits (262), Expect = 1e-22
Identities = 60/228 (26%), Positives = 112/228 (49%), Gaps = 3/228 (1%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
++ K R T R ++ + R + + TE G+ ++R T R ++E ++
Sbjct: 98 QRDREKERERQTDRERDRQREKERNRQKERERETEREGERG-RDRQTDGQR-ERERQRDA 155
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
K RE+ D+E+ ++ NR +E ERE+ + R + ERQ+++ N+ DR SER +E ER
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERR-ERERQREKENKTEDRHSERGRERER 214
Query: 252 KSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGE 311
+ E E ER R DRERDR + +R+R + E + + + E+++E ++ +
Sbjct: 215 ERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDR 274
Query: 312 MSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
K+ T + + TE + T + + + R +N R+ +
Sbjct: 275 RQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE 322
Score = 105 bits (261), Expect = 2e-22
Identities = 60/222 (27%), Positives = 117/222 (52%), Gaps = 11/222 (4%)
Query: 138 GRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREK 197
G+A + + + +E E R K +R +ER +DR +K + +R+ R++
Sbjct: 43 GQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQ-RDR 101
Query: 198 DKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGK 257
+K++E+ + +R RE ER R K R R + ER+ +RG RDR ++ ++E ER+ + K
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERER-ETEREGERG---RDRQTDGQRERERQRDAEK 157
Query: 258 EKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLS 317
E+ER DR+R+R ++ + ++R R KN + + +R++ +E+ ++ S E ++
Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERE-- 215
Query: 318 DGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
++++ ETE + T + KT + R K + R +
Sbjct: 216 ----RETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Score = 103 bits (258), Expect = 4e-22
Identities = 62/227 (27%), Positives = 115/227 (50%), Gaps = 11/227 (4%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKD 198
R T R ++ K RE E + + +R ER R+R++ + DR+ +E++
Sbjct: 224 RKRQTDRERDRQRKTEREREKQAER---ERASERETERDKERERERDRDRDRDRRQKERE 280
Query: 199 KDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKE 258
+ ++ ++ R RE ER+R + R R + ER+++R RER+R+ ER++E +R++E +E
Sbjct: 281 RQTDRKRQRRTERDRETERKRERQRER-ERERERNR-KRERERERERERERQRETERDRE 338
Query: 259 KERLRDR------DRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEM 312
KER R R DRER+R G++ R+ + E + DR+ RE ++ E+ +
Sbjct: 339 KERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK 398
Query: 313 SKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
++ +D + ETE + + + R + +GR+ D
Sbjct: 399 ERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERD 445
Score = 101 bits (251), Expect = 3e-21
Identities = 61/204 (29%), Positives = 108/204 (52%), Gaps = 25/204 (12%)
Query: 123 DAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEE-------SRVHKNTEDRGDAEIKE 175
D RR E+ + R T R +E + K R+ E +R + +R ++
Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQ 330
Query: 176 RSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
R T RDR+++ E K + R+ + D+E+ ++ G R+ ERER + R R D + ++R
Sbjct: 331 RETERDREKERERK---RKRQTEMDRERNRQTGREGRRQAERERERERER-DRQSARERE 386
Query: 236 NRERDRDSERKKETERKSE----GGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDL 291
RERDRD +R+KE ER++E G +E E+ R+R+++R+ ++G++R R R
Sbjct: 387 ERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER---------- 436
Query: 292 DREKNREHDKPEKKSASSGEMSKK 315
+++K RE D+ + +G K+
Sbjct: 437 EKQKGRERDRERQTDRQAGRQRKR 460
Score = 100 bits (250), Expect = 3e-21
Identities = 71/225 (31%), Positives = 118/225 (52%), Gaps = 16/225 (7%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR---KQKEELKEDRKPREKDKDK 201
R ++ D + RE + K E + D E ++R T R+R +++E+ +++R+ RE+ ++K
Sbjct: 139 RDRQTDGQRERERQRDAEKERERQTDRE-RQRQTERNRQKEREREKNRQERRERERQREK 197
Query: 202 EKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKS----EGGK 257
E E+ RH E RER + R +K + +RERDR +RK E ER+ E
Sbjct: 198 ENKTED---RHSERGRERERERETETETERKRQTDRERDR--QRKTEREREKQAERERAS 252
Query: 258 EKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDK-PEKKSASSGEMSKKL 316
E+E RD++RER+RD+ +DRDRR+ K E D R++ E D+ E+K E ++
Sbjct: 253 ERETERDKERERERDRDRDRDRRQ-KERERQTDRKRQRRTERDRETERKRERQRERERER 311
Query: 317 SDGTFKDSKAETETEIS-TRASKSLTTKTSKRRSKNSVEGRKEDN 360
++ + E E E R ++ K +R+ K E +E N
Sbjct: 312 ERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERN 356
Score = 97.1 bits (240), Expect = 5e-20
Identities = 68/242 (28%), Positives = 117/242 (48%), Gaps = 21/242 (8%)
Query: 135 EVKGRASLTSRSQELDNKNVREEESRVHKNTE-----DRGDAEIKERSTSRDRKQKEELK 189
E + R +E D K R E H+ + R + +ER T R+R ++ E K
Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQRE-K 119
Query: 190 EDRKPREKDKDKEKAKENGGNRHREGERERAKAR-ARPDNERQKDRGNRERDRDSERKKE 248
E + +E++++ E+ E G +R +G+RER + R A + ERQ D RER R +ER ++
Sbjct: 120 ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTD---RERQRQTERNRQ 176
Query: 249 TERKSEGGKEKERLRDRDRER-----DRDKGKDRDRRRVKNGEHSWDLDREKNREHD--- 300
ER+ E +++ R R+R RE+ DR + R+R R + E + R+ +RE D
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQR 236
Query: 301 KPEKKSASSGEMSKKLSDGTFKDSKAETETEIS---TRASKSLTTKTSKRRSKNSVEGRK 357
K E++ E + T +D + E E + R K +T ++R + + R+
Sbjct: 237 KTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRE 296
Query: 358 ED 359
+
Sbjct: 297 TE 298
Score = 97.1 bits (240), Expect = 5e-20
Identities = 59/215 (27%), Positives = 109/215 (50%), Gaps = 5/215 (2%)
Query: 145 RSQELDNKNVREEES-RVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKDKDKE 202
R +E + + RE E+ R + DR +ER RD +++ E + DR + R+ +++++
Sbjct: 117 REKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQ 176
Query: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
K +E NR ERER + + +R +RG RER+R+ E + ETERK + ++ER
Sbjct: 177 KEREREKNRQERRERERQREKENKTEDRHSERG-RERERERETETETERKRQ--TDRERD 233
Query: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFK 322
R R ER+R+K +R+R + E + +RE++R+ D+ ++ + +K T +
Sbjct: 234 RQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 323 DSKAETETEISTRASKSLTTKTSKRRSKNSVEGRK 357
D + E + E + + R + R+
Sbjct: 294 DRETERKRERQRERERERERNRKRERERERERERE 328
Score = 97.1 bits (240), Expect = 5e-20
Identities = 58/221 (26%), Positives = 115/221 (52%), Gaps = 21/221 (9%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR---KPR 195
R R + + + R++E ++ + D KER DRK++ + DR + R
Sbjct: 242 REKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301
Query: 196 EKDKDKEKAKENGGNRHREGERERAKARARP---DNERQKDRGNR-----ERDRDSERKK 247
E+ +++E+ +E R RE ERER + R R D E++++R + +R+R+ + +
Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361
Query: 248 ETERKSEGGKEKERLRDR---------DRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE 298
E R++E +E+ER RDR +R+RDRD+ K+R+R+ K+ + + ++++ RE
Sbjct: 362 EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQRERE 421
Query: 299 HDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKS 339
D+ ++ G +K G +D + +T+ + + +S
Sbjct: 422 KDRESERGRERGREREK-QKGRERDRERQTDRQAGRQRKRS 461
Score = 94.4 bits (233), Expect = 3e-19
Identities = 60/224 (26%), Positives = 112/224 (50%), Gaps = 11/224 (4%)
Query: 137 KGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPRE 196
+ R R +E + R + +DR + R RDR+++ E + D RE
Sbjct: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTD---RE 112
Query: 197 KDKDKEKAKENGGNRHREGERERAKARAR-PDNERQKDRGNRERDRDSERKKETERKSEG 255
+D+ +EK + R RE ERE + R R D +R+++ R+RD + ER+++T+R+ +
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERE---RQRDAEKERERQTDRERQR 169
Query: 256 GKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKK 315
E+ R ++R+RE++R + ++R+R+R K + + D E+ RE E++ + E +K
Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKENK-TEDRHSERGRER---ERERETETETERK 225
Query: 316 LSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
+D + +TE E +A + ++ R K R D
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269
Score = 75.9 bits (185), Expect = 1e-13
Identities = 46/193 (23%), Positives = 97/193 (50%), Gaps = 14/193 (7%)
Query: 174 KERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKD 233
+ R S++ ++ L + K + D D+E+ NR +E ER R K + + +R+++
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGD-DRER------NRQKERERRREKRQTERETDRKRE 80
Query: 234 RG---NRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWD 290
R +R R RD R+++ +R+ E ++ +R RDR RE++R++ K+R+R + GE D
Sbjct: 81 RRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRD 140
Query: 291 L----DREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSK 346
RE+ R+ D +++ + ++ ++ + + + R + K +K
Sbjct: 141 RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK 200
Query: 347 RRSKNSVEGRKED 359
++S GR+ +
Sbjct: 201 TEDRHSERGRERE 213
Score = 75.5 bits (184), Expect = 2e-13
Identities = 80/372 (21%), Positives = 147/372 (39%), Gaps = 24/372 (6%)
Query: 210 NRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKS---EGGKEKERLRDRD 266
+R R G +E + R + D +RER+R ER++ E++ E +++ER R++D
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKD 86
Query: 267 RERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKA 326
R R RD+ ++R R R K E D +R++ RE ++ +K E ++ G + +
Sbjct: 87 RHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERER-ETEREGERGRDRQTDG 145
Query: 327 ETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEI 386
+ E E A K +T + R + + R+++ K+ QE E
Sbjct: 146 QRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN------------RQERRERER 193
Query: 387 GTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPETPE 446
++ N S+ R + K++ D D + + ++E E
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE 253
Query: 447 IPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITE-SHNSDNEE 505
E R R R +RQ E Q DR +T + TE E
Sbjct: 254 RETE-----RDKERERERDRDRDRDRRQKERER-QTDRKRQRRTERDRETERKRERQRER 307
Query: 506 DDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKER 565
+ + + E E E E + + K+ +T+ D E+ +Q+ + G ++
Sbjct: 308 ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
Query: 566 SLFESAWKKEKD 577
E ++E+D
Sbjct: 368 ER-ERERERERD 378
Score = 69.3 bits (168), Expect = 1e-11
Identities = 49/251 (19%), Positives = 105/251 (41%), Gaps = 15/251 (5%)
Query: 195 REKDKDKEKAKENG-GNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKS 253
R + +E + G G H++ + + + + + ER++++ ER+ D +R++ E+
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDR 87
Query: 254 EGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHD-KPEKKSASSGEM 312
+++ R R RDRE++R++ DR+R R + E + +RE+ E + + + + G+
Sbjct: 88 HRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR 147
Query: 313 SKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSG 372
++ K+ + +T+ E + ++ + + R KN E R+ + K
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERN--RQKEREREKNRQERRERERQREK-------- 197
Query: 373 INNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAG 432
E E SE G + T + E + TE+++
Sbjct: 198 ---ENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
Query: 433 PAGQDKSEVPE 443
+DK E
Sbjct: 255 ETERDKERERE 265
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 103 bits (257), Expect = 5e-22
Identities = 57/188 (30%), Positives = 105/188 (55%), Gaps = 7/188 (3%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKDKDKEK 203
R ++ + +E E + E E + R RDR ++ + + DR K RE+ K++++
Sbjct: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDR 64
Query: 204 AKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSE----GGKEK 259
++ RE ER+R + R R + +RQ DR R++DRD ERK+ET+R E GG+E+
Sbjct: 65 QRQRERETERETERQRERQRQR-ERKRQTDR-ERDKDRDRERKRETDRNRERNRKGGRER 122
Query: 260 ERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDG 319
++ +R+R+R+R++ + R+R R + E + DRE+ R ++ E+K E K+ +
Sbjct: 123 DKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEK 182
Query: 320 TFKDSKAE 327
++ + E
Sbjct: 183 KKEEKRRE 190
Score = 95.5 bits (236), Expect = 1e-19
Identities = 55/205 (26%), Positives = 105/205 (51%), Gaps = 17/205 (8%)
Query: 157 EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGE 216
E R K DRG +ER R+R+ + E + + R++ +++++ + R R+ E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 217 RERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLR--DRDRERDRDKG 274
R+R + R R + ER+ +R RER R ERK++T+R+ + +++ER R DR+RER+R G
Sbjct: 62 RDRQRQRER-ETERETER-QRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 275 KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEIST 334
++RD++ + + + R++ RE + ++ + D + + E
Sbjct: 120 RERDKQTERERDRERERQRQRERERQRQRERKRET-------------DRERQRWAEREE 166
Query: 335 RASKSLTTKTSKRRSKNSVEGRKED 359
R + + +R+ K E R+ED
Sbjct: 167 RKKERKKERKKERKEKKKEEKRRED 191
Score = 90.1 bits (222), Expect = 6e-18
Identities = 51/186 (27%), Positives = 106/186 (56%), Gaps = 12/186 (6%)
Query: 137 KGRASLTSRSQELDNKNVREEESRV-----HKNTEDRGDAEI-KERSTSRDRKQKEELKE 190
+G+ + R ++ + +N E E+R H+ + + D E +ER RDR+++ E +
Sbjct: 13 RGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERET 72
Query: 191 DRKP-REKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKET 249
+R+ R++++ +++ ++ +R R+ +R+R + R N + +G RERD+ +ER+++
Sbjct: 73 ERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDR 132
Query: 250 ERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASS 309
ER+ ++++R R+R R+R+R + DR+R+R E +R+K R+ ++ EKK
Sbjct: 133 ERE----RQRQRERERQRQRERKRETDRERQRWAEREER-KKERKKERKKERKEKKKEEK 187
Query: 310 GEMSKK 315
KK
Sbjct: 188 RREDKK 193
Score = 79.7 bits (195), Expect = 8e-15
Identities = 52/176 (29%), Positives = 93/176 (52%), Gaps = 18/176 (10%)
Query: 135 EVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDR---KQKEELKE 190
E + R R +E D + RE+E K + + E + ER T R R +Q+E ++
Sbjct: 32 ERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQ 91
Query: 191 DRKPREKDKDKEKAKENGGNR--HREGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
+ R+KD+D+E+ +E NR +R+G RER K + RERDR+ ER+++
Sbjct: 92 TDRERDKDRDRERKRETDRNRERNRKGGRERDK------------QTERERDRERERQRQ 139
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
ER+ + +E++R DR+R+R ++ + + R+ + + + +E+ R DK K
Sbjct: 140 RERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRK 195
Score = 73.9 bits (180), Expect = 5e-13
Identities = 49/161 (30%), Positives = 89/161 (55%), Gaps = 12/161 (7%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEES-RVHKNTEDRGDAEIKERSTSRDRKQKEELKE 190
E+ R R +E D + RE E+ R + +R ++R T R+R ++ ++
Sbjct: 45 ERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRER---DKDRD 101
Query: 191 DRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETE 250
+ RE D+++E+ ++ G R ++ ERER + R ERQ+ R RER R ERK+ET+
Sbjct: 102 RERKRETDRNRERNRKGGRERDKQTERERDRER-----ERQRQR-ERERQRQRERKRETD 155
Query: 251 RKSEGGKEK-ERLRDRDRERDRD-KGKDRDRRRVKNGEHSW 289
R+ + E+ ER ++R +ER ++ K K ++ +R ++ + W
Sbjct: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKW 196
Score = 58.2 bits (139), Expect = 3e-08
Identities = 36/132 (27%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 244 ERKKETERKSEGGKEKERLRDRDRERDRDKGKDRD---RRRVKNGEHSWDLDREKNREHD 300
ER++E +R+++ GKE ER +RDR+R+R+ +R+ R+R ++ E DREK RE
Sbjct: 2 ERQRERKRETDRGKETER--ERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQ 59
Query: 301 KP-----EKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEG 355
K +++ + E ++ ++ K +T+ E + +T + R +N G
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 356 RKEDNISAKSLD 367
R+ D + + D
Sbjct: 120 RERDKQTERERD 131
Score = 52.4 bits (124), Expect = 1e-06
Identities = 28/126 (22%), Positives = 63/126 (50%), Gaps = 8/126 (6%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E+ + R T R ++ D R+ E+ ++ +G E +++ T R+R ++ E
Sbjct: 81 ERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE-RDKQTERERDRERE---- 135
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
R++ +++E+ ++ R + ER+R R ER+K+R +++ E K+ ++
Sbjct: 136 ---RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDK 192
Query: 252 KSEGGK 257
K + G+
Sbjct: 193 KRKWGE 198
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/104 (23%), Positives = 52/104 (50%), Gaps = 1/104 (0%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
+K + R T R++E + K RE + + + DR ++R R R+++ + + D
Sbjct: 97 DKDRDRERKRETDRNRERNRKGGRERDKQTERE-RDRERERQRQRERERQRQRERKRETD 155
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
R+ + + +E+ KE R +E + ++ + + R D +R+ G
Sbjct: 156 RERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 103 bits (257), Expect = 5e-22
Identities = 110/444 (24%), Positives = 203/444 (45%), Gaps = 51/444 (11%)
Query: 145 RSQELDNKNVREEES--RVHKNTEDRGDAEIKERSTS-------RDRKQKEELKEDRK-P 194
R E DN++ + S R H + R + E +R +S D +++E +E+R+
Sbjct: 607 RYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVD 666
Query: 195 REKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG-NRERDRDSERKKETERKS 253
R D+ E+A+E R R+ ERER + R R D ER+K+R RER R+ ER++E ER
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERER-DREREKERELERERAREREREREKERDR 725
Query: 254 EGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMS 313
E ++++ R+R+RER+RD+ K+R+R R + E + +RE+ RE ++ +++ +
Sbjct: 726 ERDRDRDHDRERERERERDREKERERER-EERERERERERERERERERERERARERDKER 784
Query: 314 KKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGI 373
++ D KD + E + + K+ R E + S + S
Sbjct: 785 ERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPR--QSPKRRR 842
Query: 374 NNEPNQETTTSEIGTKEAN-INSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAG 432
+ P+ + S E + + S + S SL ++ TE ++G E D
Sbjct: 843 EHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHL----TEDRQG---RWKEEDRK 895
Query: 433 PAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVS 492
P ++ S E E+ ++SS K+++ E L+ R
Sbjct: 896 PERKESSRRYEEQELKEKVSS----------------VDKQREQTEILESSR----MRAQ 935
Query: 493 NVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYE 552
++I + D E D+ A + + ++I+ + +E++ G+ + +ET +
Sbjct: 936 DIIGHHQSEDRETSDR----AHDENKKKAKIQKKPIKKKKEDDV--GIERGNIETTSEDG 989
Query: 553 KLQQSPKPGEKERSLFESAWKKEK 576
++ SPK G+K++S+ E KK K
Sbjct: 990 QV-FSPKKGQKKKSI-EKKRKKSK 1011
Score = 86.7 bits (213), Expect = 7e-17
Identities = 84/328 (25%), Positives = 139/328 (42%), Gaps = 35/328 (10%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTE-DRGDAEIKERSTSRDRKQKEELKE 190
E+ + R R +E + + R+ E + E +R +ER RDR++ +
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDH 733
Query: 191 DR---KPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
DR + RE+D++KE+ +E R RE ERER + R R ER+++R RERD++ ER++
Sbjct: 734 DRERERERERDREKERERER-EERERERERERERERER---ERERERA-RERDKERERQR 788
Query: 248 ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVK-----NGEHSWDLDREKNREHDKP 302
+ E K +G ++ R+ RE DR+ D R+ K G S ++ REH P
Sbjct: 789 DWEDKDKGRDDRREKREEIRE-DRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREH-SP 846
Query: 303 EKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED--- 359
+ + +SG+ D K S S + T R+ + E RK +
Sbjct: 847 DSDAYNSGD------DKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKE 900
Query: 360 ---NISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCEN------ 410
+ L VS ++ + Q + +I S+D S R +
Sbjct: 901 SSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKA 960
Query: 411 -IQPNPTEKQKGDSTSDAEGDAGPAGQD 437
IQ P +K+K D G+ +D
Sbjct: 961 KIQKKPIKKKKEDDVGIERGNIETTSED 988
Score = 69.7 bits (169), Expect = 9e-12
Identities = 57/231 (24%), Positives = 113/231 (48%), Gaps = 23/231 (9%)
Query: 162 HKNTEDRGDAEIKERSTSRDRKQKE--ELKEDRKPREKDKDKEKAKENGGNRHREGERER 219
H++ +D+ + S SRDR++ + E+ +RK R D+ K + R+ R
Sbjct: 1215 HRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRI-DQLKRGEPSRSTSSDRQDSRSH 1273
Query: 220 AKARARPDNERQ----------------KDRGNRERDRDSERKKETERKSEGGKEKE--R 261
+ R+ P+++RQ +DR +R+R+ ER+ +R+ + +K+ R
Sbjct: 1274 SSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPR 1333
Query: 262 LRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTF 321
RDRDR R+R++ ++RD+RR + E + R+ D+ ++ S ++
Sbjct: 1334 NRDRDRLRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAK 1393
Query: 322 KDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSG 372
+ + E + E ++R S +L K + SV+G +E N S ++ +S+ +G
Sbjct: 1394 LEGEHERDLESTSRDSLAL-DKERMDKDLGSVQGFEETNKSERT-ESLEAG 1442
Score = 67.0 bits (162), Expect = 6e-11
Identities = 63/339 (18%), Positives = 129/339 (38%), Gaps = 17/339 (5%)
Query: 118 KLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERS 177
+L + A R EK + R +E + + R+ E + E+R +ER
Sbjct: 706 ELERERAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERE 765
Query: 178 TSRDR-KQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGN 236
R+R +++E +E K RE+ +D E + +R + E R R ++ +K +
Sbjct: 766 RERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKR 825
Query: 237 RERDRDSERKKETERKSEGGKEKERLRDRDRERDRDK-----GKDRDRRRVKNGEHSWDL 291
+ ++ +R+ E + + D + ++ + + ++ R + + D
Sbjct: 826 YRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDR 885
Query: 292 DREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEI---STRASKSLTTKTSKRR 348
E KPE+K +S ++L + K +TEI S ++ +
Sbjct: 886 QGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSED 945
Query: 349 SKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRC 408
+ S E+ AK I +P ++ ++G + NI +TS + +
Sbjct: 946 RETSDRAHDENKKKAK--------IQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKG 997
Query: 409 ENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPETPEI 447
+ + +++K SD + K P TP I
Sbjct: 998 QKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPI 1036
Score = 64.7 bits (156), Expect = 3e-10
Identities = 64/242 (26%), Positives = 102/242 (42%), Gaps = 38/242 (15%)
Query: 144 SRSQELDNKNVREEESRVHKNTEDR------GDAEIKERSTSRDRKQKEELKEDRKPREK 197
SRS D ++ R SR DR G + ++R RDR
Sbjct: 1260 SRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDR--------------Y 1305
Query: 198 DKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGK 257
+ D+E+ +E R RE +R+ K D R +D R+R R+ ER++E +++ + +
Sbjct: 1306 EHDRERERERRDTRQREWDRDADK-----DWPRNRD---RDRLRERERERERDKRRDLDR 1357
Query: 258 EKERLRDRDRERDRDKGKDR-----DRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEM 312
E+ERL ERDRD+ +DR VK E + + E++ E + + M
Sbjct: 1358 ERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERM 1417
Query: 313 SKKLS--DGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIV 370
K L G + +K+E + +S K S S G + IS LD I+
Sbjct: 1418 DKDLGSVQGFEETNKSERTESLEAGDDES---KLDDAHSLGSGAGEGYEPISDDELDEIL 1474
Query: 371 SG 372
+G
Sbjct: 1475 AG 1476
Score = 59.3 bits (142), Expect = 1e-08
Identities = 89/455 (19%), Positives = 159/455 (34%), Gaps = 54/455 (11%)
Query: 162 HKNTEDRGDAEIKERSTSRDRKQKEE----------LKEDRKPREKDKDKEKAKENGGNR 211
H ++ + + I+ S S RK+ L+ P ++ R
Sbjct: 331 HHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPR 390
Query: 212 HREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDR 271
HR RE+ + ++ R R D +R +E + + E E+++ RD DR
Sbjct: 391 HRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDR 450
Query: 272 DKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETE 331
+ RDRR D ++R + + S EM +D +T+
Sbjct: 451 EPRDGRDRR---------DARDTRDRRELRDSRDMRDSREM---------RDYSRDTKES 492
Query: 332 ISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEA 391
R S+S R + RKED +S S N +E++ +EI +
Sbjct: 493 RDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESR----SYGRNHLREESSRTEIRNESR 548
Query: 392 NINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAG-----QDKSEVPETPE 446
N + + I +D R + P + +G S + + + + +S PE
Sbjct: 549 NESRSEIRNDRMGRSR-GRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDR 607
Query: 447 IP--------------NELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVS 492
P RR R RP+ P ++ Q + L+ D + V
Sbjct: 608 YPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSP-IRHQGRNDELERDERREERRVD 666
Query: 493 NVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYE 552
V E D + + + E + E E E + ++ E ++D E
Sbjct: 667 RVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRE 726
Query: 553 KLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLR 587
+ + E+ER E +KE++ +E E+ R
Sbjct: 727 RDRDRDHDRERERER-ERDREKEREREREERERER 760
Score = 53.1 bits (126), Expect = 8e-07
Identities = 66/254 (25%), Positives = 110/254 (43%), Gaps = 23/254 (9%)
Query: 120 SSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTS 179
SSD R + + + + SRS D+++ +E R + E +ER
Sbjct: 1264 SSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRE-------RERER- 1315
Query: 180 RDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQK---DRGN 236
RD +Q+E ++ K +++D+++ +E RE ERER K R D ER++ D
Sbjct: 1316 RDTRQREWDRDADKDWPRNRDRDRLRE------RERERERDKRRDL-DRERERLISDSVE 1368
Query: 237 RERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKN 296
R+RDRD +R E+ + E K E + + ERD + RD + DL +
Sbjct: 1369 RDRDRDRDRTFESS-QIESVKRCEAKLEGEHERDLE-STSRDSLALDKERMDKDLGSVQG 1426
Query: 297 -REHDKPEK-KSASSGEMSKKLSDGTFKDSKA-ETETEISTRASKSLTTKTSKRRSKNSV 353
E +K E+ +S +G+ KL D S A E IS + +++R
Sbjct: 1427 FEETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEPISDDELDEILAGDAEKREDQQD 1486
Query: 354 EGRKEDNISAKSLD 367
E + D + +D
Sbjct: 1487 EEKMPDPLDVIDVD 1500
Score = 52.0 bits (123), Expect = 2e-06
Identities = 41/183 (22%), Positives = 82/183 (44%), Gaps = 14/183 (7%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKA 204
R +E D++ RE E + + R D E ++ RDR+ + ++ R+ R+ ++
Sbjct: 424 RDREKDSREEREYEQDQSSSRDHRDDREPRD---GRDRRDARDTRDRRELRDSRDMRDSR 480
Query: 205 KENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRD 264
+ +R + R+ +R+ D +DR RD+ RK++T + + LR+
Sbjct: 481 EMRDYSRDTKESRDPRDSRSTRDAHDYRDR----EGRDTHRKEDTYPEESRSYGRNHLRE 536
Query: 265 R-DRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASS--GEMSKKLSDGTF 321
R R++ ++ R ++N + R + R + PEK S S ++ S+ +
Sbjct: 537 ESSRTEIRNESRNESRSEIRNDR----MGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNY 592
Query: 322 KDS 324
DS
Sbjct: 593 HDS 595
Score = 50.4 bits (119), Expect = 5e-06
Identities = 115/628 (18%), Positives = 245/628 (39%), Gaps = 116/628 (18%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKE-ELKEDRKPREKD---KD 200
R +E D K R+E SR ++ + E+KE+ +S D+++++ E+ E + R +D
Sbjct: 888 RWKEEDRKPERKESSRRYE------EQELKEKVSSVDKQREQTEILESSRMRAQDIIGHH 941
Query: 201 KEKAKENGGNRHREGERERAKARARPDNERQKD-----RGNRERDRDS---------ERK 246
+ + +E H E ++ +AK + +P ++++D RGN E + ++K
Sbjct: 942 QSEDRETSDRAHDENKK-KAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKK 1000
Query: 247 KETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKN---------- 296
K E+K + K + D + + K + + E ++ KN
Sbjct: 1001 KSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKE 1060
Query: 297 -------REHDKPEKKSASSGEMSKKLS---------------------------DGTFK 322
+ D P++ + E + + T
Sbjct: 1061 DTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPATLA 1120
Query: 323 DSKAETETEISTRA----SKSLTTKTSKRRSKNSVEGRKEDNISAKSLD----SIVSGIN 374
+ A T ST A + + T T+ N RK + ++ +I +
Sbjct: 1121 ATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIEDAQH 1180
Query: 375 NEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPA 434
+P + +S +G+ +N + T S LR + N + + GD S +
Sbjct: 1181 RKPMDQKRSSSLGSNRSNRSHT------SGRLRSPS---NDSAHRSGDDQSGRKRVLHSG 1231
Query: 435 GQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNV 494
+D+ E ++ EI E S I ++ R +R RQDS R S ++ V
Sbjct: 1232 SRDR-EKTKSLEITGERKSRIDQLKRGEPSRSTSS--DRQDSRS--HSSRRSSPESDRQV 1286
Query: 495 ITESHNSDN----EEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKD 550
+ S + D+ +E D++ + + + + +++ ++ E +++
Sbjct: 1287 HSRSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERE 1346
Query: 551 YEKLQQSPKPGEKERSLFESAWK-----KEKDIVSKEIEKLR-----------TSIQTLC 594
E+ ++ E+ER + +S + +++ S +IE ++ +++
Sbjct: 1347 RERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTS 1406
Query: 595 KSALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAE-L 653
+ +L L K + + +D+ ++Q + SE + EA E ++ D L + E
Sbjct: 1407 RDSLALDK--ERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDD--AHSLGSGAGEGY 1462
Query: 654 EQLIKDQQDKICAVKANILKNEEKIQKM 681
E + D+ D+I A A ++++ +KM
Sbjct: 1463 EPISDDELDEILAGDAEKREDQQDEEKM 1490
Score = 48.5 bits (114), Expect = 2e-05
Identities = 38/194 (19%), Positives = 76/194 (39%), Gaps = 9/194 (4%)
Query: 150 DNKNVREEESRVHKNTED-RGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENG 208
D++ + R H+ ED RG +R +D +++ E ++D+ +D + ++
Sbjct: 402 DHERTSQSHDRRHERREDTRG-----KRDREKDSREEREYEQDQSSSRDHRDDREPRDGR 456
Query: 209 GNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRE 268
R R+R + R D ++ + RD R R + + RD
Sbjct: 457 DRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTH 516
Query: 269 RDRDKGKDRDRRRVKN---GEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSK 325
R D + R +N E S R ++R + E ++ G ++ + K S+
Sbjct: 517 RKEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSR 576
Query: 326 AETETEISTRASKS 339
++I + +S S
Sbjct: 577 GSRGSQIDSHSSNS 590
Score = 42.7 bits (99), Expect = 0.001
Identities = 71/380 (18%), Positives = 135/380 (35%), Gaps = 36/380 (9%)
Query: 162 HKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAK 221
++ + +R +++ER + K+++ E +K ++ KE+ RHRE E +
Sbjct: 74 YRRSPERPTGDLRERMKN---KRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKIT 130
Query: 222 ARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLR-DRDRERDRDKGKDRDRR 280
P++E + RD + E E +R + R+ + + ++
Sbjct: 131 KERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREE 190
Query: 281 RVKNGEHSWDLDREKNREHDKPEKKSAS-SGEMSKKLSDGTFKDSKAETETEISTRASKS 339
+ E S ++ R K K S S + S K S + KD K + ++
Sbjct: 191 IIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRN 250
Query: 340 LTTKTSKRRSKNSVE-----------GRK-------EDNISAKSLDSIVSGINNEPNQE- 380
T SK++ + G+K +D I K+ D G + E +E
Sbjct: 251 SKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREK 310
Query: 381 ----TTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQ------KGDSTSDAEGD 430
+TS G + I+S S + + + P+P K+ + T
Sbjct: 311 RDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRS 370
Query: 431 AGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEAL--QMDRSGSG 488
A P P+ + P S +R R R + +R + E + DR
Sbjct: 371 ASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDS 430
Query: 489 KTVSNVITESHNSDNEEDDQ 508
+ + +S + DD+
Sbjct: 431 REEREYEQDQSSSRDHRDDR 450
Score = 40.8 bits (94), Expect = 0.004
Identities = 48/198 (24%), Positives = 81/198 (40%), Gaps = 29/198 (14%)
Query: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
+ K N R ER R R N+RQ D D+E +K +S KE
Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQ--------DVDTEPQKRNTEESSSPVRKESS 117
Query: 263 RDRDRERD-----RDKGKDRDRRRVK---------NGEHSWD----LDREKNREHDKPEK 304
R R RE++ +++ + + V+ NG+ ++D L E R+ + E
Sbjct: 118 RGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQREL 177
Query: 305 KSASSGEMSKKLSDGTFKDSKAE-TETEISTRASKSLTTKTSKRRS--KNSVEGRKEDNI 361
M K+ K+ E +++S S ++K+ KR+S K+S +K+
Sbjct: 178 MKLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKT 237
Query: 362 SAKSLDSIVSGINNEPNQ 379
SA S + N++ NQ
Sbjct: 238 SAVSSPLLDQQRNSKTNQ 255
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 102 bits (253), Expect = 2e-21
Identities = 66/227 (29%), Positives = 116/227 (51%), Gaps = 14/227 (6%)
Query: 134 GEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDA-EIKERSTSRDRKQKEELKEDR 192
G+ A R +E D + E+ R DR + KE + +RDR+++ E++ DR
Sbjct: 66 GQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDR 125
Query: 193 KPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERK 252
+ REK K +E+ ++ G R R+ +RE+ + R + + ER+RD ER+K+ ER+
Sbjct: 126 E-REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERE 184
Query: 253 SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEM 312
+E ++++R RD ++ER+R ++RDR+R E + DRE RE D+ E
Sbjct: 185 TE--RDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRR-------ER 235
Query: 313 SKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
+ G +D + + + E R + + +R+ K E R+ED
Sbjct: 236 QRDRDRGKERDRERDRKEE---RKKERKKERKKERKEKKKEEKRRED 279
Score = 101 bits (251), Expect = 3e-21
Identities = 63/201 (31%), Positives = 107/201 (53%), Gaps = 25/201 (12%)
Query: 143 TSRSQELDNKNVRE---EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKD 198
T + ++ D K RE +E ++N + EI ER R++++ E + DR + RE+D
Sbjct: 88 TEKERDRDRKRDRERRRKEKETNRNRDREKQTEI-ERDREREKQKGRERERDRGRERERD 146
Query: 199 KDKEKAKENGGNRHREGERERAKARARP-DNERQKDRGNR-----------------ERD 240
+D+EK +E + R+G+RE R R + E+QK+R +R+
Sbjct: 147 RDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRE 206
Query: 241 RDSERKKETERKSEGGKEKERLRD--RDRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE 298
RD +RK +TER+ E +E ER D R+R+RDRD+GK+RDR R + E + +E+ +E
Sbjct: 207 RDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKE 266
Query: 299 HDKPEKKSASSGEMSKKLSDG 319
+ +K+ + +K +G
Sbjct: 267 RKEKKKEEKRREDKKRKWGEG 287
Score = 80.5 bits (197), Expect = 5e-15
Identities = 45/176 (25%), Positives = 91/176 (51%), Gaps = 6/176 (3%)
Query: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
L PR + +G +R RE +R R K D +R++DR R +++++ R +
Sbjct: 54 LGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETNRNR 113
Query: 248 ETERKSEGGKEKERLRDRDRERDRDKG--KDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
+ E+++E +++ER + + RER+RD+G ++RDR R K E + DR+ RE + ++
Sbjct: 114 DREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERER 173
Query: 306 SASSGEMSKKLSD---GTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKE 358
+ ++ ++ +D++ E E + + T+T ++R + EG +E
Sbjct: 174 DREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDR-EGERE 228
Score = 60.8 bits (146), Expect = 4e-09
Identities = 40/156 (25%), Positives = 81/156 (51%), Gaps = 13/156 (8%)
Query: 210 NRHREGERERAKARARPDNERQKDRGNRERDRD-----SERKKETERKSE---GGKEKER 261
+R R G +E ++ + D +R+R+RD +E++++ +RK + KEKE
Sbjct: 50 SRGRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRERRRKEKET 109
Query: 262 LRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTF 321
R+RDRE+ + +DR+R + K E D RE+ R+ D+ +++ ++K DG
Sbjct: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERE----RQTEKDRDGQ- 164
Query: 322 KDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRK 357
++++ E E + K T+ + R +++ + R+
Sbjct: 165 RETETERERDREREKQKERETERDRDRQRDTEKERE 200
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 101 bits (252), Expect = 2e-21
Identities = 107/430 (24%), Positives = 191/430 (44%), Gaps = 46/430 (10%)
Query: 182 RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDR 241
R Q E + RE+++++E+ NR RE ERER + D ER++ + RER+R
Sbjct: 389 RVQYTETEPYHNYRERERERERE-----NRQRERERERER-----DRERERRQRERERER 438
Query: 242 DSERKKETE-RKSEGGKEKERLRDRDRE-RDRDKGKDRDRRRVKNGEHSWDLDREKNREH 299
+ ER KE + RK E +E+ + ++DR+ RDRD+ K+R++ + K S + +R+
Sbjct: 439 EHERDKERQRRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRS---PQPPSRQA 495
Query: 300 DKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
+ P+K++A++G K+ + +KD +++ + S++ ++RR K S
Sbjct: 496 EPPKKEAATTGPQVKRADE--WKDPWRRSKSP-KKKLGVSVSPSRARRRRKTSASSASAS 552
Query: 360 NISAKSLDSIV---SGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPT 416
N S S S SG + ++ ++ S ++ + +S S S S S + P+PT
Sbjct: 553 NSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSF-SSSPSPSPT 611
Query: 417 EKQKGDS---TSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKR 473
S + G AG+ + P P P + + +P P +P PR R
Sbjct: 612 PSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEP--TKPGDPREAR 669
Query: 474 QDSMEALQMDR----SGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAV 529
+ A R SGSG + S++ + V + +S + +A
Sbjct: 670 RKERPARTPPRRRTLSGSGSGSGS----SYSGSSSRSRSLSVSSVSSVSSATS-SSSSAH 724
Query: 530 ELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTS 589
++ E+ + L + +SP P + + E K++D V +E K +S
Sbjct: 725 SVDSEDMYADLASPVSSAS------SRSPAPAQTRK---EKGKSKKEDGVKEEKRKRDSS 775
Query: 590 IQTLCKSALP 599
Q KSA P
Sbjct: 776 TQP-PKSAKP 784
Score = 42.7 bits (99), Expect = 0.001
Identities = 72/384 (18%), Positives = 132/384 (34%), Gaps = 82/384 (21%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELK---EDRKPREKDKDK 201
R +E + + RE E R + +R KER ++ ++E K +DR+ R++D++K
Sbjct: 415 RERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRDEKDRQHRDRDREK 474
Query: 202 EKAKENGGNR-------HREGERERAKARA---------------RPDNERQKDRGNRER 239
E+ KE G + R+ E + +A R +K G
Sbjct: 475 EREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGVSVS 534
Query: 240 DRDSERKKETERKSEGGKEKERLRDRDRE-------RDRDKGKDRDRRRVKNGEHS-WDL 291
+ R+++T S R R R R + ++ HS +
Sbjct: 535 PSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSG 594
Query: 292 DREKNREHD--------------------KPEKKSASSGEMSKK---------------- 315
R ++R +P +GE S K
Sbjct: 595 SRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTA 654
Query: 316 -----LSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIV 370
G ++++ + + ++L+ S S S + ++S S+ S+
Sbjct: 655 PVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVS 714
Query: 371 SGINNEPNQETTTSE--IGTKEANINSTSISDDNSASLRCENIQPNPT-----EKQKGDS 423
S ++ + + SE + ++S S A R E + EK+K DS
Sbjct: 715 SATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDS 774
Query: 424 TSDAEGDAGP-AGQDKSEVPETPE 446
++ A P AG S+ P TP+
Sbjct: 775 STQPPKSAKPPAGGKSSQQPSTPQ 798
Score = 41.2 bits (95), Expect = 0.003
Identities = 48/210 (22%), Positives = 81/210 (38%), Gaps = 29/210 (13%)
Query: 147 QELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR--KPREKDKDKEKA 204
Q+LD VR D D E R S++ + +EDR +P+ +D+D E
Sbjct: 36 QDLDGAGVR---------ASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVN 86
Query: 205 KENGG-------NRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGK 257
+ + G EGE +R + ++ E D D E +E
Sbjct: 87 ELSRGPTSSPCEEEGDEGEEDRTSDLRDEASSVTRELDEHELDYDEEVPEE----PAPAV 142
Query: 258 EKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLS 317
+++ E D +KG+ R K G S + +++ E K +KK GE +
Sbjct: 143 QEDEAEKAGAEDDEEKGEGTPREEGKAGVQS--VGEKESLEAAKEKKKEDDDGE----ID 196
Query: 318 DGTFKDSKAETETEISTRASKSLTTKTSKR 347
DG D E E E+ + + + + + R
Sbjct: 197 DGEIDDDDLE-EGEVKDPSDRKVRPRPTCR 225
Score = 37.7 bits (86), Expect = 0.036
Identities = 39/251 (15%), Positives = 95/251 (37%), Gaps = 21/251 (8%)
Query: 121 SDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSR 180
S R + V S +S + +D++++ + + + R A + R
Sbjct: 698 SSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKG 757
Query: 181 DRKQKEELKEDRKPREKDKDKEKAKEN--GGNRHREGERERAKARARPDN---------- 228
K+++ +KE+++ R+ K+ + GG ++ + +P
Sbjct: 758 KSKKEDGVKEEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIK 817
Query: 229 ----ERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKN 284
+ D+G+R+R S++ +++ ++ RDR+ G + R+
Sbjct: 818 LTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQ 877
Query: 285 GEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRAS-----KS 339
+ ++ R+ K S+ + K SD +K+ + +S R K+
Sbjct: 878 NSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELLKQLKA 937
Query: 340 LTTKTSKRRSK 350
+ +++R+K
Sbjct: 938 VEDAIARKRAK 948
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 98.2 bits (243), Expect = 2e-20
Identities = 61/187 (32%), Positives = 102/187 (54%), Gaps = 23/187 (12%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-----KPREKDK 199
R +E D + R +ES+ +R +ER+ RDR ++ E + DR + RE+D+
Sbjct: 23 RRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDR 82
Query: 200 DK------EKAKENGGNRHREGERERAKARARP-----DNERQKDR-----GNRERDRDS 243
D+ E+ KE +RH E +RER K + R D ER+K + +R+ D
Sbjct: 83 DRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDR 142
Query: 244 ERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR-VKNGEHSWDLDREKNREHDKP 302
ER+++ ER+ E G+E+ + DR RER+R++ ++R+R+R K E D++RE+ RE D+
Sbjct: 143 ERERQAERERETGRER-KTEDRHRERERERKRERERKRETKERERHTDMERERQRETDRK 201
Query: 303 EKKSASS 309
+ S
Sbjct: 202 RDRQRES 208
Score = 88.2 bits (217), Expect = 2e-17
Identities = 60/210 (28%), Positives = 101/210 (48%), Gaps = 22/210 (10%)
Query: 155 REEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHRE 214
+ E H TE + R T R+R + +E K + + E+D+ +++ + NR R+
Sbjct: 4 KTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRER----NRERD 59
Query: 215 GERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKG 274
+RER K R + ERQ RER+RD +R++ETER+ + +E +R + DRER + K
Sbjct: 60 RDREREKQTDR-EGERQ-----RERERDRDRQRETERERDKERETDRHTETDRERQKQKE 113
Query: 275 ------KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAET 328
+DR+R + K DRE +RE ++ ++ +G K +D E
Sbjct: 114 REMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKT------EDRHRER 167
Query: 329 ETEISTRASKSLTTKTSKRRSKNSVEGRKE 358
E E + TK +R + E ++E
Sbjct: 168 ERERKRERERKRETKERERHTDMERERQRE 197
Score = 84.7 bits (208), Expect = 3e-16
Identities = 58/159 (36%), Positives = 85/159 (53%), Gaps = 8/159 (5%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDR---KQKEE 187
E+ + R T R E + R+ + + + TE D E + +R T DR KQKE
Sbjct: 57 ERDRDREREKQTDREGERQRERERDRDRQ--RETERERDKERETDRHTETDRERQKQKER 114
Query: 188 LKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKK 247
E + RE++K KE +E +R + ERER R R + R++ +R R+R+ ERK+
Sbjct: 115 EMERVRDREREKQKEMGRERQTDRETDRERERQAERER-ETGRERKTEDRHRERERERKR 173
Query: 248 ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGE 286
E ERK E KE+ER D +RER R+ + RDR+R E
Sbjct: 174 ERERKRET-KERERHTDMERERQRETDRKRDRQRESERE 211
Score = 80.5 bits (197), Expect = 5e-15
Identities = 60/198 (30%), Positives = 99/198 (50%), Gaps = 34/198 (17%)
Query: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGG-NRHREGERERAKARARPDN 228
+++ + R T + + + +E R RE D+++++AKE+ +RH E +R+R D
Sbjct: 2 ESKTEGRHTHTETETMDRQRERR--RETDRERDRAKESKTEDRHSERDRQR-------DR 52
Query: 229 ERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDR--------DRERDRDKGKDRDRR 280
ER NRERDRD ER+K+T+R+ E +E+ER RDR D+ER+ D+ + DR
Sbjct: 53 ER-----NRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRE 107
Query: 281 RVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSL 340
R K E + R++ RE K EM ++ T +++ E E +
Sbjct: 108 RQKQKEREMERVRDREREKQK---------EMGRERQ--TDRETDRERERQAERERETGR 156
Query: 341 TTKTSKRRSKNSVEGRKE 358
KT R + E ++E
Sbjct: 157 ERKTEDRHRERERERKRE 174
Score = 72.4 bits (176), Expect = 1e-12
Identities = 56/166 (33%), Positives = 84/166 (50%), Gaps = 17/166 (10%)
Query: 117 NKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTE-DRGDAEIKE 175
N+ D R +GE + R R ++ + + R++E ++TE DR + KE
Sbjct: 55 NRERDRDREREKQTDREGE-RQRERERDRDRQRETERERDKERETDRHTETDRERQKQKE 113
Query: 176 RSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRG 235
R R R ++ E K+ RE+ D+E +E R R+ ERER R R +R ++R
Sbjct: 114 REMERVRDRERE-KQKEMGRERQTDRETDRE----RERQAERERETGRERKTEDRHRER- 167
Query: 236 NRERDRDSERKKET-ERKSEGGKEKERLRDRDR--------ERDRD 272
RER R+ ERK+ET ER+ E+ER R+ DR ER+RD
Sbjct: 168 ERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESERERD 213
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 95.9 bits (237), Expect = 1e-19
Identities = 76/297 (25%), Positives = 144/297 (48%), Gaps = 26/297 (8%)
Query: 136 VKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPR 195
V+ R S + R ++ R SR H + E G + +R R+ K+++ L+ + K R
Sbjct: 255 VERRRSRSPRRSLSPRRSPRRSRSRSH-HREGHGSSSF-DRELERE-KERQRLEREAKER 311
Query: 196 EKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEG 255
EK++ + ++ + G R R RER ++R+R +DR RDRD ER+KE ER
Sbjct: 312 EKERRRSRSIDRGLERRRSRSRERHRSRSR-----SRDRKGDRRDRDREREKENER---- 362
Query: 256 GKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNRE--HDKPEKKSASSGEMS 313
G+ ++R D++R +R+K ++R R R K +++ +K++E D+ + +
Sbjct: 363 GRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKE 422
Query: 314 KKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKS-----LDS 368
KK S ++ K + + S A K +++ ++ SK+ E +++ N ++S DS
Sbjct: 423 KKHSRSRSRERKHRSRSR-SRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDS 481
Query: 369 IVSGINNE--PNQETTTSEIGTKE----ANINSTSISDDNSASLRCENIQPNPTEKQ 419
+ E P++E + +KE + + + D R ++I+ EKQ
Sbjct: 482 VEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQ 538
Score = 78.6 bits (192), Expect = 2e-14
Identities = 53/226 (23%), Positives = 106/226 (46%), Gaps = 10/226 (4%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E+ + R SRS+ D K R + R + +RG ++R ++R + E KE
Sbjct: 326 ERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERG--RRRDRDYDKERGNERE-KER 382
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
+ RE+ K++ E +H+E + +R R R D K R R ERK +
Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDR---RHRDDKRDSKKEKKHSRSRSRERKHRSRS 439
Query: 252 KSEGGKEKERLRDRDR-ERDRDKGKDRDRRRVKNGE--HSWDLDREKNREHDKPEKKSAS 308
+S ++ R R +++ + +++ K++ +R ++G + +++ K REH ++KS
Sbjct: 440 RSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRK 499
Query: 309 SGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVE 354
++ DSK +++ R S+S+ ++ +++ KN E
Sbjct: 500 RSRSKERSHKRDHSDSKDQSDKH-DRRRSQSIEQESQEKQHKNKDE 544
Score = 68.2 bits (165), Expect = 2e-11
Identities = 67/270 (24%), Positives = 116/270 (42%), Gaps = 20/270 (7%)
Query: 173 IKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQK 232
I ++ +R RK K++ KE + E D+ E+ + R R ++R+R + ++
Sbjct: 229 IDQQIKTRPRKIKKDGKEGAE--EIDRHVERRRSRSPRRSLSPRRSPRRSRSR--SHHRE 284
Query: 233 DRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLD 292
G+ DR+ ER+KE +R KE+E+ R R R DR + R R R ++ S D
Sbjct: 285 GHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD 344
Query: 293 RE-KNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKN 351
R+ R+ D+ +K G + D + ++ E E E S SK ++RS+
Sbjct: 345 RKGDRRDRDREREKENERGRRRDRDYDKE-RGNEREKERERSRERSK-------EQRSRG 396
Query: 352 SVEGR--KEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCE 409
VE + KED + D + +E S ++E S S S + R
Sbjct: 397 EVEEKKHKEDKDDRRHRDD-----KRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSR 451
Query: 410 NIQPNPTEKQKGDSTSDAEGDAGPAGQDKS 439
+ + + K + S+ +G G+ S
Sbjct: 452 SKEKSSKHKNESKEKSNKRSRSGSQGRTDS 481
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 93.2 bits (230), Expect = 7e-19
Identities = 59/188 (31%), Positives = 104/188 (55%), Gaps = 12/188 (6%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKA 204
R + K RE+E + + +++ + +ER R+RK+KE K+ ++ REK++ K K
Sbjct: 40 RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKK 99
Query: 205 KENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRD 264
++ R + G RER K + R + ER+ ++ RER R RKK +R+ E +EKER +
Sbjct: 100 EKKKRERKQRGRRERKKKKERKERERE-NKQRRERKRKKRRKK--KRRKERKREKERGK- 155
Query: 265 RDRERDRDKGKDRDRRRVKN-GEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKD 323
R+R+R + K ++R+++R +N E + +R++ RE K KK + K KD
Sbjct: 156 RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK-------KD 208
Query: 324 SKAETETE 331
K + +T+
Sbjct: 209 RKTDRQTD 216
Score = 90.5 bits (223), Expect = 5e-18
Identities = 59/204 (28%), Positives = 102/204 (50%), Gaps = 8/204 (3%)
Query: 111 IGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGD 170
I K C + S RR K E + +E + RE + ++R
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 171 AEIKERSTSRDRKQKEELKEDRKPR------EKDKDKEKAKENGGNRHREGERERAKARA 224
+ R R +++KE+ K +RK R +K + KE+ +EN R R+ ++ R K R
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKR- 143
Query: 225 RPDNERQKDRGNRERDRDSERKKETERKSE-GGKEKERLRDRDRERDRDKGKDRDRRRVK 283
R + +R+K+RG RER R +K+E E+K E KE+++ R+R R+R K + ++RR+ K
Sbjct: 144 RKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKK 203
Query: 284 NGEHSWDLDREKNREHDKPEKKSA 307
+ DR+ + + +P ++SA
Sbjct: 204 ERKKDRKTDRQTDSQVFRPLRESA 227
Score = 85.5 bits (210), Expect = 2e-16
Identities = 52/194 (26%), Positives = 106/194 (54%), Gaps = 10/194 (5%)
Query: 143 TSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKE 202
T R E + E+ + + E + + KE+ + R++ +E + RK REK + +
Sbjct: 30 TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89
Query: 203 KAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
+ KE R R+ E+++ + + R ER+K + +ER+R++++++E +RK K +++
Sbjct: 90 REKE---RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRK----KRRKKK 142
Query: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSK--KLSDGT 320
R ++R+R++++GK R+R+R K + + RE+NR+ K E++ E K K
Sbjct: 143 RRKERKREKERGK-RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRK 201
Query: 321 FKDSKAETETEIST 334
K+ K + +T+ T
Sbjct: 202 KKERKKDRKTDRQT 215
Score = 84.7 bits (208), Expect = 3e-16
Identities = 59/202 (29%), Positives = 100/202 (49%), Gaps = 13/202 (6%)
Query: 159 SRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERE 218
S + K R KER RK++ E + R+ +K+K K K +E G R R+ +E
Sbjct: 23 SHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERK-RKE 81
Query: 219 RAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRD 278
R K R K+R +ER + + KK+ ERK G +E+++ ++R +ER+R+ + R+
Sbjct: 82 REKQR--------KERREKERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRE 132
Query: 279 RRRVKNGEHSWDLDREKNREHDKPE-KKSASSGEMSKKLSDGTFKDSKAETETEISTRAS 337
R+R K + +R++ +E K E K+ E +K + K+ K E E + R
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERK--ERRE 190
Query: 338 KSLTTKTSKRRSKNSVEGRKED 359
+ K +R+ K + RK D
Sbjct: 191 RKKERKKERRKKKERKKDRKTD 212
Score = 60.8 bits (146), Expect = 4e-09
Identities = 37/146 (25%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Query: 216 ERERAKARARPDNERQKDRGNRERDRDSERKKETERKS-EGGKEKERLRDRDRERDRDKG 274
+RE + + R + E++K +ER R+ +K++ +RK E GKE+ER R ++RE+ R +
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQRKER 89
Query: 275 KDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEIST 334
++++RR+ K + + + RE K +++ E ++ K K + E
Sbjct: 90 REKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKR 149
Query: 335 RASKSLTTKTSKRRSKNSVEGRKEDN 360
+ + K+R K E ++E N
Sbjct: 150 EKERGKRERKRKKRKKEEREKKRERN 175
Score = 54.7 bits (130), Expect = 3e-07
Identities = 41/131 (31%), Positives = 62/131 (47%), Gaps = 14/131 (10%)
Query: 241 RDSERKKETERKSEGGKEKERLRDRDR-------ERDRDKGKDRDRRRVKNGEHSWDLDR 293
R+SERKKE + + +E+E+ R R+R + R++GK+R+R+R K E R
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKR-KEREKQRKERR 90
Query: 294 EKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSV 353
EK R K EKK + ++ + K + E E E R + K KRR K
Sbjct: 91 EKERRKRKKEKKKRERKQRGRR--ERKKKKERKERERENKQRRER----KRKKRRKKKRR 144
Query: 354 EGRKEDNISAK 364
+ RK + K
Sbjct: 145 KERKREKERGK 155
Score = 42.4 bits (98), Expect = 0.001
Identities = 22/96 (22%), Positives = 47/96 (48%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKD 198
R + + + K +E R K + + + K+R +R ++KE +++R+ R+K+
Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
Query: 199 KDKEKAKENGGNRHREGERERAKARARPDNERQKDR 234
+ KE+ K+ + R+ +R+ RP E +R
Sbjct: 195 RKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNR 230
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 90.1 bits (222), Expect = 6e-18
Identities = 60/182 (32%), Positives = 101/182 (55%), Gaps = 8/182 (4%)
Query: 126 RRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQK 185
+R A E+ K R R ++ R+ + E GD ++R T +R+++
Sbjct: 69 QRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGD---RDRETETERQEE 125
Query: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSER 245
E + DRK REKD+++++ +E G ++ RE E E+ + R R E ++ R +RER+R +R
Sbjct: 126 RERQRDRK-REKDRERQRQREIGIDKDREIETEKDRDREREMGETERYR-DRERERQKQR 183
Query: 246 KKETERKSEGGKEKE-RLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
+ +R E +EKE R RDRDR+++R+ KDR R R + + DRE+ RE D+ +
Sbjct: 184 ETRRDRDRERQREKEDRERDRDRQKERE--KDRYRERETGRDRDKERDRERQREKDRDRQ 241
Query: 305 KS 306
K+
Sbjct: 242 KA 243
Score = 89.7 bits (221), Expect = 8e-18
Identities = 52/175 (29%), Positives = 95/175 (54%), Gaps = 14/175 (8%)
Query: 145 RSQELDNKNVRE---EESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR-KPREKDKD 200
R +E K +E E+ R + DR +ER RDR +K E DR + E ++
Sbjct: 64 RERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQ 123
Query: 201 KEKAKENGGNRHREGERERAK---------ARARPDNERQKDRGNRERDRDSERKKETER 251
+E+ ++ R ++ ER+R + D +R+++ G ER RD ER+++ +R
Sbjct: 124 EERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQR 183
Query: 252 KSEGGKEKERLRDR-DRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
++ +++ER R++ DRERDRD+ K+R++ R + E D D+E++RE + + +
Sbjct: 184 ETRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDR 238
Score = 87.8 bits (216), Expect = 3e-17
Identities = 61/183 (33%), Positives = 99/183 (54%), Gaps = 18/183 (9%)
Query: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR 192
+ +++ R L R + +RE E + +R KER +DR+ +++ R
Sbjct: 36 RSQIEDRDVLILRGSRVAPAIIRERE---RQRERERQRKRAKERHREKDREIEKDRDRQR 92
Query: 193 K---PREKDKDKEKAKENGGNRHREGERERAKARARP-DNERQKDRGNR-------ERDR 241
K R++ +D+++ +E G+R RE E ER + R R D +R+KDR + ++DR
Sbjct: 93 KRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDR 152
Query: 242 DSERKKETERKSEGGKEKERLRDRDRER--DRDKGKDRDRRRVKNGE-HSWDLDREKNRE 298
+ E +K+ +R+ E G E ER RDR+RER R+ +DRDR R + E D DR+K RE
Sbjct: 153 EIETEKDRDREREMG-ETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKERE 211
Query: 299 HDK 301
D+
Sbjct: 212 KDR 214
Score = 81.6 bits (200), Expect = 2e-15
Identities = 58/206 (28%), Positives = 112/206 (54%), Gaps = 20/206 (9%)
Query: 171 AEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNER 230
A I+ER R+R+++ + ++R REKD++ EK ++ R R+ +RER + R D +R
Sbjct: 55 AIIRERERQRERERQRKRAKERH-REKDREIEKDRD----RQRKRDRERQRWR---DRDR 106
Query: 231 QKDR-GNRERDRDSERKKETERKSEGGKEKERLRDR------DRERDRDKGKDRDRRRVK 283
+++R G+R+R+ ++ER++E ER+ + +EK+R R R D++R+ + KDRDR R +
Sbjct: 107 KRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRER-E 165
Query: 284 NGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTK 343
GE DRE+ R+ + ++ +K +D + E E + + T
Sbjct: 166 MGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKD----RYRERETG 221
Query: 344 TSKRRSKNSVEGRKEDNISAKSLDSI 369
+ + ++ R++D K++D +
Sbjct: 222 RDRDKERDRERQREKDRDRQKAIDCV 247
Score = 34.3 bits (77), Expect = 0.40
Identities = 22/83 (26%), Positives = 36/83 (43%), Gaps = 1/83 (1%)
Query: 123 DAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR 182
D R + E+ + R R D R+ E + DR K+R R+
Sbjct: 161 DREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRERET 220
Query: 183 KQKEELKEDR-KPREKDKDKEKA 204
+ + + DR + REKD+D++KA
Sbjct: 221 GRDRDKERDRERQREKDRDRQKA 243
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 89.0 bits (219), Expect = 1e-17
Identities = 61/212 (28%), Positives = 103/212 (48%), Gaps = 22/212 (10%)
Query: 154 VREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHR 213
V E + ++ K TE+ RD + K+E K++R+ REK++++E+ + R
Sbjct: 227 VEELKEKLRKRTEE----------PDRDERLKKE-KQEREEREKEREREREERERKRRRE 275
Query: 214 EGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRER---- 269
E ERE+ +AR R +R + R +R R S+R+ R + + +ER R R R+R
Sbjct: 276 EEEREKERARDRERRKRSRSR-SRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 270 --DRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE 327
DR + K R R R + S D K+R + ++ S E K+ SD D K+
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD----DKKSS 390
Query: 328 TETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
++ + S+ T++ + +KN V G ED
Sbjct: 391 VKSGSREKQSEDTNTESKESDTKNEVNGTSED 422
Score = 84.7 bits (208), Expect = 3e-16
Identities = 55/187 (29%), Positives = 97/187 (51%), Gaps = 13/187 (6%)
Query: 147 QELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKE 206
+E + + RE E R K + + E KER+ R+R+++ + R D+ ++++
Sbjct: 255 EEREKEREREREERERKRRREEEERE-KERARDRERRKRSRSRSRHSSRTSDRRCSRSRD 313
Query: 207 NGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRD 266
+ +R RE R R++ R R + + +R +R R RD R K +RKS + K R R++D
Sbjct: 314 HKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQD 373
Query: 267 RE-RDRDK-GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
R+ ++++K G D + VK+G REK E E K + +K +GT +D
Sbjct: 374 RKSKEKEKRGSDDKKSSVKSG------SREKQSEDTNTESKESD----TKNEVNGTSEDI 423
Query: 325 KAETETE 331
K+E +T+
Sbjct: 424 KSEGDTQ 430
Score = 77.4 bits (189), Expect = 4e-14
Identities = 49/195 (25%), Positives = 94/195 (48%), Gaps = 8/195 (4%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKD 198
+ L R++E D R+E + K + + E + R+RK++ E +E K R +D
Sbjct: 231 KEKLRKRTEEPD----RDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARD 286
Query: 199 KDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKE 258
+++ K + +RH +R +R+R D++R + R R R R +R++ K
Sbjct: 287 RERRK-RSRSRSRHSSRTSDRRCSRSR-DHKRSRSR-ERRRSRSRDRRRSRSHDRSERKH 343
Query: 259 KERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSD 318
+ R RDR R + RD+ + R + ++ E +EK + +K S SG K+ D
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQD-RKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Query: 319 GTFKDSKAETETEIS 333
+ +++T+ E++
Sbjct: 403 TNTESKESDTKNEVN 417
Score = 70.5 bits (171), Expect = 5e-12
Identities = 55/215 (25%), Positives = 96/215 (44%), Gaps = 25/215 (11%)
Query: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSER 245
EELKE + R ++ D++ ER K + ER+K+R +R+ +R
Sbjct: 228 EELKEKLRKRTEEPDRD---------------ERLKKEKQEREEREKEREREREERERKR 272
Query: 246 KK-ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
++ E ER+ E +++ER R R R R R + DRR ++ +H RE+ R + +
Sbjct: 273 RREEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR 331
Query: 305 KSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKR-RSKNSVEGRKEDNISA 363
+S S +K S++ +R KS ++ R R ++ KE S
Sbjct: 332 RSRSHDRSERK------HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
Query: 364 KSLDSIVSGINNEPNQETTT-SEIGTKEANINSTS 397
S+ SG + +++T T S+ + +N TS
Sbjct: 386 DKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420
Score = 52.8 bits (125), Expect = 1e-06
Identities = 54/234 (23%), Positives = 95/234 (40%), Gaps = 23/234 (9%)
Query: 212 HREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDR 271
H G++ A+ + E K++ + R +E +R KEK+ +R++ER+R
Sbjct: 211 HLMGKQHMGYAKIKATVEELKEKLRK-------RTEEPDRDERLKKEKQEREEREKERER 263
Query: 272 DKGKDRDRRRVKNGEHSWDLDREKNREHDKP-EKKSASSGEMSKKLSD---GTFKDSKAE 327
++ ++R+R+R + E +REK R D+ K+S S S + SD +D K
Sbjct: 264 ER-EERERKRRREEE-----EREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 328 TETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIG 387
E S+ S RS+ R D +KS D + +
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR--KSYKHRSKSRDREQDRK 375
Query: 388 TKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQD-KSE 440
+KE SDD +S++ + + + SD + + +D KSE
Sbjct: 376 SKEKEKRG---SDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 89.0 bits (219), Expect = 1e-17
Identities = 61/212 (28%), Positives = 103/212 (48%), Gaps = 22/212 (10%)
Query: 154 VREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHR 213
V E + ++ K TE+ RD + K+E K++R+ REK++++E+ + R
Sbjct: 227 VEELKEKLRKRTEE----------PDRDERLKKE-KQEREEREKEREREREERERKRRRE 275
Query: 214 EGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRER---- 269
E ERE+ +AR R +R + R +R R S+R+ R + + +ER R R R+R
Sbjct: 276 EEEREKERARDRERRKRSRSR-SRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSR 334
Query: 270 --DRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE 327
DR + K R R R + S D K+R + ++ S E K+ SD D K+
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD----DKKSS 390
Query: 328 TETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
++ + S+ T++ + +KN V G ED
Sbjct: 391 VKSGSREKQSEDTNTESKESDTKNEVNGTSED 422
Score = 84.7 bits (208), Expect = 3e-16
Identities = 55/187 (29%), Positives = 97/187 (51%), Gaps = 13/187 (6%)
Query: 147 QELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKE 206
+E + + RE E R K + + E KER+ R+R+++ + R D+ ++++
Sbjct: 255 EEREKEREREREERERKRRREEEERE-KERARDRERRKRSRSRSRHSSRTSDRRCSRSRD 313
Query: 207 NGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRD 266
+ +R RE R R++ R R + + +R +R R RD R K +RKS + K R R++D
Sbjct: 314 HKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQD 373
Query: 267 RE-RDRDK-GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
R+ ++++K G D + VK+G REK E E K + +K +GT +D
Sbjct: 374 RKSKEKEKRGSDDKKSSVKSG------SREKQSEDTNTESKESD----TKNEVNGTSEDI 423
Query: 325 KAETETE 331
K+E +T+
Sbjct: 424 KSEGDTQ 430
Score = 77.4 bits (189), Expect = 4e-14
Identities = 49/195 (25%), Positives = 94/195 (48%), Gaps = 8/195 (4%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKD 198
+ L R++E D R+E + K + + E + R+RK++ E +E K R +D
Sbjct: 231 KEKLRKRTEEPD----RDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARD 286
Query: 199 KDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKE 258
+++ K + +RH +R +R+R D++R + R R R R +R++ K
Sbjct: 287 RERRK-RSRSRSRHSSRTSDRRCSRSR-DHKRSRSR-ERRRSRSRDRRRSRSHDRSERKH 343
Query: 259 KERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSD 318
+ R RDR R + RD+ + R + ++ E +EK + +K S SG K+ D
Sbjct: 344 RSRSRDRRRSKSRDRKSYKHRSKSRDREQD-RKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Query: 319 GTFKDSKAETETEIS 333
+ +++T+ E++
Sbjct: 403 TNTESKESDTKNEVN 417
Score = 70.5 bits (171), Expect = 5e-12
Identities = 55/215 (25%), Positives = 96/215 (44%), Gaps = 25/215 (11%)
Query: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSER 245
EELKE + R ++ D++ ER K + ER+K+R +R+ +R
Sbjct: 228 EELKEKLRKRTEEPDRD---------------ERLKKEKQEREEREKEREREREERERKR 272
Query: 246 KK-ETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEK 304
++ E ER+ E +++ER R R R R R + DRR ++ +H RE+ R + +
Sbjct: 273 RREEEEREKERARDRER-RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR 331
Query: 305 KSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKR-RSKNSVEGRKEDNISA 363
+S S +K S++ +R KS ++ R R ++ KE S
Sbjct: 332 RSRSHDRSERK------HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD 385
Query: 364 KSLDSIVSGINNEPNQETTT-SEIGTKEANINSTS 397
S+ SG + +++T T S+ + +N TS
Sbjct: 386 DKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTS 420
Score = 52.8 bits (125), Expect = 1e-06
Identities = 54/234 (23%), Positives = 95/234 (40%), Gaps = 23/234 (9%)
Query: 212 HREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDR 271
H G++ A+ + E K++ + R +E +R KEK+ +R++ER+R
Sbjct: 211 HLMGKQHMGYAKIKATVEELKEKLRK-------RTEEPDRDERLKKEKQEREEREKERER 263
Query: 272 DKGKDRDRRRVKNGEHSWDLDREKNREHDKP-EKKSASSGEMSKKLSD---GTFKDSKAE 327
++ ++R+R+R + E +REK R D+ K+S S S + SD +D K
Sbjct: 264 ER-EERERKRRREEE-----EREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRS 317
Query: 328 TETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIG 387
E S+ S RS+ R D +KS D + +
Sbjct: 318 RSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDR--KSYKHRSKSRDREQDRK 375
Query: 388 TKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQD-KSE 440
+KE SDD +S++ + + + SD + + +D KSE
Sbjct: 376 SKEKEKRG---SDDKKSSVKSGSREKQSEDTNTESKESDTKNEVNGTSEDIKSE 426
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 89.0 bits (219), Expect = 1e-17
Identities = 62/233 (26%), Positives = 108/233 (46%), Gaps = 20/233 (8%)
Query: 144 SRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEK 203
SRS+ + K + E R H++ R ++ R S+D+ K+ E+ +E DK +
Sbjct: 43 SRSRSRERKRKSDNEGRKHRS---RSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGR 99
Query: 204 AK----ENGGNRHREGERE--------RAKARARPDNERQKDRGNRERDRDSERKKETER 251
+ ENG +RH+ ER+ R+++R R R ++R + R R ERKK R
Sbjct: 100 ERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRER-KKSRSRSRERKKSRSR 158
Query: 252 KSEGGKEKERLRDRDRE-RDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSG 310
E K + R R+R R R R + + R R R ++ + R++ + +KP + S S
Sbjct: 159 SRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRS-- 216
Query: 311 EMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISA 363
+S+ S F+ + + + K ++R K VE +K+ I+A
Sbjct: 217 -LSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAA 268
Score = 62.4 bits (150), Expect = 1e-09
Identities = 50/201 (24%), Positives = 83/201 (41%), Gaps = 15/201 (7%)
Query: 178 TSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARP-DNE----RQK 232
T RD E+ DR ++K++ + H R R++ R R DNE R +
Sbjct: 6 TERDGLAPEKTSPDRD-KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSR 64
Query: 233 DRGNRERDRDSERKKETERKSEGGKEKERLRDRDRER------DRDKGKDRDRRRVKNGE 286
R R +S+ K + KSE +KE D+ RER D+ K ++R+ +
Sbjct: 65 SRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRS 124
Query: 287 HSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSK 346
HS RE+ E+K + S +K S ++ K ++ +R K S+
Sbjct: 125 HSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK---KSRSRSRERKRRIRSRSR 181
Query: 347 RRSKNSVEGRKEDNISAKSLD 367
RS++ R ++S D
Sbjct: 182 SRSRHRHRTRSRSRTRSRSRD 202
Score = 57.8 bits (138), Expect = 3e-08
Identities = 41/174 (23%), Positives = 75/174 (43%), Gaps = 2/174 (1%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E KGR L S D +E +S ++ E + RS SR+RK+ +
Sbjct: 92 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 151
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
RK + + + +E+ K +R R+ R R+++R+R + + +R R R +RKK E+
Sbjct: 152 RK-KSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 209
Query: 252 KSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
+ R R R+ D + E + L ++ +E + +K+
Sbjct: 210 PRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 263
Score = 52.8 bits (125), Expect = 1e-06
Identities = 48/224 (21%), Positives = 94/224 (41%), Gaps = 23/224 (10%)
Query: 120 SSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTS 179
SS++ R E+ +GR+ SRS+E +++ SR K + R K RS S
Sbjct: 104 SSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS----RSRERKKSRSRSRERKKSRSRS 159
Query: 180 RDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRER 239
R+RK+ +RK R + + + ++ RHR R R++ R+R +R+R
Sbjct: 160 RERKKSRSRSRERKRRIRSRSRSRS------RHRHRTRSRSRTRSR----------SRDR 203
Query: 240 DRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREH 299
+ E+ + R R R+ D + R R K + + + + ++
Sbjct: 204 KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 263
Query: 300 DKPEKKSASSG---EMSKKLSDGTFKDSKAETETEISTRASKSL 340
+ +A+ G ++ L+ GT + +++ +K+L
Sbjct: 264 QEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKAL 307
Score = 33.5 bits (75), Expect = 0.68
Identities = 45/245 (18%), Positives = 84/245 (34%), Gaps = 28/245 (11%)
Query: 240 DRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREH 299
DRD ++++ S + R R R R+R + D + R+ ++R
Sbjct: 19 DRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK------------HRSRSR 66
Query: 300 DKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKED 359
K ++ S + SKK D + ++ S KR+ + S GR
Sbjct: 67 SKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHS 126
Query: 360 NISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQ 419
++S + + E + + S K + + + + R I+ +
Sbjct: 127 R--SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRS 184
Query: 420 KGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPP----RVKRQD 475
+ + + +D+ + E P RR R S P+PP R D
Sbjct: 185 RHRHRTRSRSRTRSRSRDRKKRIEKP----------RRFSRSLSRTPSPPPFRGRNTAMD 234
Query: 476 SMEAL 480
+ EAL
Sbjct: 235 AQEAL 239
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 88.6 bits (218), Expect = 2e-17
Identities = 61/224 (27%), Positives = 111/224 (49%), Gaps = 16/224 (7%)
Query: 94 RIVAGHEPERTNELLQIIGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKN 153
+ ++ + N LQ++ ++K + + + + E++ R + K
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKE 62
Query: 154 VREEESRVHKNTEDR----GDAEIK--ERSTSRDRKQKEELKEDRKPREKDKDKEKAKEN 207
RE E R + ++R G E K + R+RK++ KE+++ EK+K K+K K+
Sbjct: 63 RREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE 122
Query: 208 GGNRHREG-ERERAKARARPDN-ERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDR 265
G +EG ERER + R R + ER++ + RE++R+ + +K+ ERK G KE+ER
Sbjct: 123 RGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182
Query: 266 DRER--------DRDKGKDRDRRRVKNGEHSWDLDREKNREHDK 301
+ER +R K ++R RR + E +R+K R+ D+
Sbjct: 183 RKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226
Score = 88.6 bits (218), Expect = 2e-17
Identities = 49/160 (30%), Positives = 88/160 (55%), Gaps = 8/160 (5%)
Query: 132 EKGE-VKGRASLTSRSQELDNKNVREEESRVHKNTEDRG--DAEIKERSTSRDRKQKEEL 188
+KGE K R +E +NK E+E R K ++RG E KER +RK++E
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145
Query: 189 KEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKE 248
+ +RK E++K++E+ + R + GE+E + ++++R +ER ++ ERK+
Sbjct: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205
Query: 249 TERKSEGGKEKERLRDRDRE-----RDRDKGKDRDRRRVK 283
ERK E K++ER ++R ++ R++++GK + R K
Sbjct: 206 RERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 86.3 bits (212), Expect = 9e-17
Identities = 61/216 (28%), Positives = 108/216 (50%), Gaps = 22/216 (10%)
Query: 154 VREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHR 213
+RE E + E + KER + R ++++E K R+ REK++ +E+ K+ +
Sbjct: 38 IREREREIETRKEGK-----KERESERKKERREREKRKRE-REKERKRERGKKEKKGERK 91
Query: 214 EGERERAKARARPDN------ERQKDRGNRERDRDSERKKETERKSEGGKE--KERLR-- 263
+ ERER K R +N E++K + +ER R S+ KE ERK E +E KER R
Sbjct: 92 KEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Query: 264 -DRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFK 322
+R++ER+R + K R+R++V E + K +E + +K+ + E K+ +
Sbjct: 152 EEREKERERKERKKRERKQVGEKE-----EERKEKERKERKKRERNRKERKKERERKERR 206
Query: 323 DSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKE 358
+ K E + + + + +T+ R + RKE
Sbjct: 207 ERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 86.3 bits (212), Expect = 9e-17
Identities = 58/174 (33%), Positives = 95/174 (54%), Gaps = 12/174 (6%)
Query: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDR 192
K E KG R ++ K RE+E++ + E R E KER + ++ E KE+R
Sbjct: 83 KKEKKGERKKEERERK---KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139
Query: 193 KPREKDKDKEKAKENGGNRHREGERERAKARARPD-NERQKDRGNRERDRDSERKKETER 251
K RE+ K++E+ KE R +E ER+ K R R E++++R +ER ERKK
Sbjct: 140 K-REERKERERKKEE---REKERERKERKKRERKQVGEKEEERKEKER---KERKKRERN 192
Query: 252 KSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
+ E KE+ER R+R+++R K ++R + R K+ + +W ++E+ + K KK
Sbjct: 193 RKERKKERERKERRERKKERKKKEERKKERQKDRQTNW-REKERGKRERKERKK 245
Score = 77.4 bits (189), Expect = 4e-14
Identities = 62/225 (27%), Positives = 113/225 (50%), Gaps = 19/225 (8%)
Query: 139 RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKD 198
++ + R +E++ + ++E R + ++R + E ++R ++RK +E K+++K K
Sbjct: 35 QSEIREREREIETRKEGKKE-RESERKKERREREKRKREREKERK-RERGKKEKKGERKK 92
Query: 199 KDKEKAKENGGNRHREGE-RERAKARARPDNERQKDRGNRERDRDSERK----KETERKS 253
+++E+ K ++EGE +E+ K + + + R G +ER+R ERK KE ERK
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG-KERERKEERKREERKERERKK 151
Query: 254 EGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMS 313
E +EKER R ++R+R + +++ R K E RE+NR+ K E++ E
Sbjct: 152 E-EREKERERKERKKRERKQVGEKEEER-KEKERKERKKRERNRKERKKERERKERRERK 209
Query: 314 KKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKE 358
K+ + K E + E R T K R K + RK+
Sbjct: 210 KE------RKKKEERKKE---RQKDRQTNWREKERGKRERKERKK 245
Score = 77.4 bits (189), Expect = 4e-14
Identities = 50/163 (30%), Positives = 88/163 (53%), Gaps = 13/163 (7%)
Query: 122 DDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRD 181
++ R+ EK +G + +E + +E + + E+R E KER ++
Sbjct: 93 EERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKE 152
Query: 182 RKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDR 241
++KE +++RK RE+ + EK +E +E ER+ K R R ER+K+R +ER
Sbjct: 153 EREKERERKERKKRERKQVGEKEEE-----RKEKERKERKKRERNRKERKKERERKER-- 205
Query: 242 DSERKKETERKSEGGKEKERLRDRD---RERDRDKGKDRDRRR 281
ERKKE ++K E ++KER +DR RE++R K + ++R++
Sbjct: 206 -RERKKERKKKEE--RKKERQKDRQTNWREKERGKRERKERKK 245
Score = 77.0 bits (188), Expect = 5e-14
Identities = 49/206 (23%), Positives = 103/206 (50%), Gaps = 13/206 (6%)
Query: 165 TEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARA 224
T+ +EI+ER ++ E KE +K RE ++ KE+ + R RE E+ER + R
Sbjct: 30 TQPGWQSEIRERE-----REIETRKEGKKERESERKKERRERE--KRKREREKERKRERG 82
Query: 225 RPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKN 284
+ E++ +R ER+R R+++ ++ E +++++ ++R R +GK+R+R+ +
Sbjct: 83 K--KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERK 140
Query: 285 GEHSWDLDR---EKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLT 341
E + +R E+ +E ++ E+K ++ +K + K+ K + E R +
Sbjct: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE-RNRKERKKE 199
Query: 342 TKTSKRRSKNSVEGRKEDNISAKSLD 367
+ +RR + +KE+ + D
Sbjct: 200 RERKERRERKKERKKKEERKKERQKD 225
Score = 52.0 bits (123), Expect = 2e-06
Identities = 42/159 (26%), Positives = 70/159 (44%), Gaps = 8/159 (5%)
Query: 237 RERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRR---VKNGEHSWDLDR 293
RER+R+ E +KE +++ E ++KER R+R++ R R++ K+R R R K GE +
Sbjct: 39 REREREIETRKEGKKERESERKKER-REREK-RKREREKERKRERGKKEKKGERKKEERE 96
Query: 294 EKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSV 353
K R +K K+ + KK + SK E E R + + +R K
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERE---RKEERKREERKERERKKEE 153
Query: 354 EGRKEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEAN 392
++ + K + G E +E E +E N
Sbjct: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 82.8 bits (203), Expect = 1e-15
Identities = 85/362 (23%), Positives = 154/362 (42%), Gaps = 32/362 (8%)
Query: 133 KGEVKGRASLTSRSQELDNKNVREEESRVHKNTE-DRGDAEIKERSTSRDRKQKEELKED 191
K + K A +S ++ D+K+ +++ +V KN + D ++K+ + S D + + K++
Sbjct: 285 KKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDS-KDE 343
Query: 192 RKPREKDKDKEKA--KENGGNRHREG-ERERAKARARPDNERQKDRGNRERDRDSERKKE 248
RK +KDK K K K+ ++ E + E A+ ++ R + ++ D+ + KK
Sbjct: 344 RKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKI 403
Query: 249 TERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
T + + + +D ++D+ K +++ VKN E S D D E + K +K
Sbjct: 404 TFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKK 463
Query: 309 SGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKE---------D 359
+ SKK D KD+K E ST L K K+ SK +K+ +
Sbjct: 464 GKKDSKK--DDKKKDAKKNAE---STEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTE 518
Query: 360 NISAKSLDSIVSGINNE---PNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPT 416
+ A+ +S +G +T + E K SD SA+ + E ++
Sbjct: 519 STDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSKMEGLESKRG 578
Query: 417 EKQKGDSTS-DAEGDAGPAGQ--DKSEVPETPEI-PNELSSNIRRI------PRPGSARP 466
+ T+ + +G+ G+ E P P P+ S +RR+ P P R
Sbjct: 579 FRMSSKKTTFNEKGEKASTGRVPPSREKPPLPACEPSLPSPKVRRLCWCKMPPPPPKPRY 638
Query: 467 AP 468
AP
Sbjct: 639 AP 640
Score = 56.2 bits (134), Expect = 1e-07
Identities = 85/453 (18%), Positives = 178/453 (39%), Gaps = 28/453 (6%)
Query: 15 KVIRRPPLTEKLLSKPPFRYLHDIITEVIRMT-GFMKGLYTDAEMKSDNVKDKDAKISFL 73
K+++ PP+ + PFR+L+ T + + K +K D+ K K +
Sbjct: 83 KILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDS-KKKGGSYATN 141
Query: 74 QKAIDVVVMVSGEPLLAKPARIVAGHEPERTNELLQIIGKCCLNKLSSDDAVRRVLAGEK 133
++ +V + A + + HE E++ + N S + +K
Sbjct: 142 PESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSK---SSSETNPESQNSKTVSKNCSQK 198
Query: 134 GEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRD------RKQKEE 187
+ + S + ++ L KN +++ + K + D E S + D + E
Sbjct: 199 DKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDES 258
Query: 188 LKEDRKPREKDKDKEK----------AKENGGNRHREGERERAKARARPDNERQKDRGNR 237
+ D R ++ K K+ N + + E ++ + ++ + +
Sbjct: 259 INFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVK 318
Query: 238 ERDRDSERKKETE-RKSEGGKEKERLRD--RDRERDRDKGKDRDRRRVKNGEHSWDLDRE 294
+ D+ + KK+TE +E G K+ +D +D+++ + K +D ++ + D +
Sbjct: 319 KDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAK 378
Query: 295 KNREHDKPEKKSASSGEMSKKLSDGTFK-DSKAETETEISTRASKSLTTKTSKRRSKNSV 353
R + KK++ + + K TF DS++E E++ S + K K SK +K SV
Sbjct: 379 DARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKK-DKKDSKTDNKKSV 437
Query: 354 EGRKE--DNISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENI 411
+ +E D S DS + + ++ + + K+A N+ S ++ L+ +
Sbjct: 438 KNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKK 497
Query: 412 QPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPET 444
+ K D DA D + E +T
Sbjct: 498 HSKEKKGSKKDIKKDARKDTESTDAEFDESSKT 530
Score = 47.8 bits (112), Expect = 3e-05
Identities = 48/227 (21%), Positives = 98/227 (43%), Gaps = 20/227 (8%)
Query: 132 EKGEVKGRASLTSRSQELDNKN--VREEESRVHKNTEDRGDAEIKE--RSTSRDRK---- 183
E G+ K A SR+ + +KN +++ ++ +T+ + E KE + +D+K
Sbjct: 373 ESGDAKD-ARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKT 431
Query: 184 -QKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRD 242
K+ +K D + + D + + + G ++G+++ K + D ++ + E D +
Sbjct: 432 DNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLE 491
Query: 243 SERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKP 302
++ K+ ++ +G K +D ++D K + + K + D
Sbjct: 492 LKKDKKHSKEKKGSK-------KDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTE 544
Query: 303 EKKSASSGEMSKKL--SDGTFKDSKAE-TETEISTRASKSLTTKTSK 346
++S KK+ SDGT +SK E E++ R S TT K
Sbjct: 545 SEESLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEK 591
Score = 37.7 bits (86), Expect = 0.036
Identities = 75/366 (20%), Positives = 149/366 (40%), Gaps = 67/366 (18%)
Query: 294 EKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSV 353
++ E DK KS+ E SKK SK+ +ET ++ SK++ SKN
Sbjct: 153 KRQNEADKTPLKSSHENEQSKK--------SKSSSETNPESQNSKTV--------SKNCS 196
Query: 354 EGRKEDNISAKSLDSIVSGINNEPNQE----TTTSEIGTKEANINSTSI--------SDD 401
+ K+D+ ++K ++ N P ++ T+++ ++ + NS ++ SDD
Sbjct: 197 QKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDD 256
Query: 402 NSASLRC--ENIQPNPTE--------------KQKGDSTSDAEG-DAGPAGQDKSEVPET 444
S + N N ++ K+ +SDAE D+ A +D +V +
Sbjct: 257 ESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKN 316
Query: 445 PEIPNELSSNIRRIPRPGSARPAPPRVKRQDS---MEALQMD--RSGSGKTVSNVITESH 499
+ ++ ++++ A + +R+D+ + L+ D + + K + TES
Sbjct: 317 VK-KDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESG 375
Query: 500 NS-DNEEDDQFVVEAAPQLSEMSEIEMVT-----AVELEEEEKHGGLVKKILETKKDYEK 553
++ D D + + +A+ + + + +T ELE +E K ++K D +K
Sbjct: 376 DAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKK 435
Query: 554 ----------LQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKI 603
PK K+ E KK+ K+ + + + T +S L L K
Sbjct: 436 SVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKD 495
Query: 604 MDYIQE 609
+ +E
Sbjct: 496 KKHSKE 501
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 82.4 bits (202), Expect = 1e-15
Identities = 83/340 (24%), Positives = 143/340 (42%), Gaps = 47/340 (13%)
Query: 117 NKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKER 176
N D +V K + + ++ S+S+E D+K+ R EE R+ ++ R +KE+
Sbjct: 441 NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEK 500
Query: 177 STSRDRKQKEELKEDRKPREKDKDKE-KAKENGGNRHREGERERAKARARP--------- 226
D K K++ E + +EK K E K+ E+ ++ +E +R RA++R+R
Sbjct: 501 EKQSDSKGKDQ--ERSRSKEKSKQLESKSNEHDHSKSKEKDR-RAQSRSRECDITKGKHS 557
Query: 227 ------DNERQKDRGNRER----DRDSERKKETER-KSEGGKEKERLRDRDRERDRDKGK 275
+ R +DR R R DRD R KE R + + + + R R R+R + +
Sbjct: 558 YNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSR 617
Query: 276 DRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTR 335
+DRRR + S + + ++R DK + + S K +E+E
Sbjct: 618 SKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSH------------RKENSESE---- 661
Query: 336 ASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEANINS 395
K + +K+ S N+ +K D + S +N E +S + KE
Sbjct: 662 --KRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDN----ELKSSMLKNKEDEKIR 715
Query: 396 TSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAG 435
+S+ +N S EN + K K D S D +G
Sbjct: 716 SSVEKENQKSKGQENDHVHEKNK-KFDHESSPGTDEDKSG 754
Score = 81.3 bits (199), Expect = 3e-15
Identities = 72/323 (22%), Positives = 148/323 (45%), Gaps = 26/323 (8%)
Query: 146 SQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAK 205
S+ + KN +E++ + HK+ KER R+ ++ ++ K K R K K + K+K
Sbjct: 413 SESPNRKNEKEKKVKDHKSNS-------KERDIRRNSEKDDKYKNKVKKRAKSKSRSKSK 465
Query: 206 ENGGNRHREGERERAKARARPDNERQKDRGN-RERDRDSERKKETERKSEGGKEKERLRD 264
E ++ R+ + R + + + +D N +E+++ S+ K + + +S ++ ++L
Sbjct: 466 EKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 265 RDRERDRDKGKDRDRRR--------VKNGEHSWD-LDREKNREHDKPEKKSASSGEMSKK 315
+ E D K K++DRR + G+HS++ RE++R D+ + + + + +
Sbjct: 526 KSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRS 585
Query: 316 LSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINN 375
S + + E +R S+ T + RSK+ R+ D+ S++ +S +
Sbjct: 586 RSKEYHRYREQEYRRRGRSR-SRERRTPPGRSRSKDR-RRRRRDSRSSEREESQSRNKDK 643
Query: 376 EPNQETTTS---EIGTKEANINSTS---ISDDNSASLRCENIQPNPTEKQKGDSTSDAEG 429
NQE+ +S E E + S S S +NS + + Q +P K K S +
Sbjct: 644 YRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQ-SPFSKIKQSSQDNELK 702
Query: 430 DAGPAGQDKSEVPETPEIPNELS 452
+ ++ ++ + E N+ S
Sbjct: 703 SSMLKNKEDEKIRSSVEKENQKS 725
Score = 63.9 bits (154), Expect = 5e-10
Identities = 104/507 (20%), Positives = 192/507 (37%), Gaps = 98/507 (19%)
Query: 100 EPERTNELLQIIGKCCLNKLSSDDAVRRVLAGEKG-EVKGRASLTSR--SQELDNKNVRE 156
E ER N + +C RR+L G ++KGR R S+ R
Sbjct: 296 EKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRR 355
Query: 157 EESRVHKNTEDRGDAEIKERSTSR----DRKQKEELKEDRKP--REKDKDKEKAKENGGN 210
E+ H E + ++ S R D+ + E+KE+++ R K++ + +
Sbjct: 356 SETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSES 415
Query: 211 RHREGERERAKARARPDNERQKD-RGNRERDRDSERKKETERKSEG---GKEKERLRDRD 266
+R+ E+E+ K + N +++D R N E+D + K + KS+ KEK + ++RD
Sbjct: 416 PNRKNEKEK-KVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERD 474
Query: 267 RERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKA 326
+ +R++ K R R R K R+H+ ++K +K SD KD
Sbjct: 475 SKHNRNEEK---RMR----------SRSKGRDHENVKEK--------EKQSDSKGKDQ-- 511
Query: 327 ETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEI 386
E S SK L +K+++ S E + ++ D I G ++ ++ S
Sbjct: 512 --ERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECD-ITKGKHSYNSRTRERSRS 568
Query: 387 GTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPETPE 446
+ + S + D S S + ++ G+ +S TP
Sbjct: 569 RDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRR---------------GRSRSRERRTP- 612
Query: 447 IPNELSSNIRRIPRPGSARPAPPRVKRQD--SMEALQMDRSGSGKTVSNVITESHNSDNE 504
PG +R R +R+D S E + K + SH +N
Sbjct: 613 --------------PGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENS 658
Query: 505 EDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKE 564
E + + + + + + KK + + K++QS + E +
Sbjct: 659 ESE----------------KRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELK 702
Query: 565 RSLFESAWKKEKDIVSKEIEKLRTSIQ 591
S+ + +KE EK+R+S++
Sbjct: 703 SSMLK----------NKEDEKIRSSVE 719
Score = 54.7 bits (130), Expect = 3e-07
Identities = 74/402 (18%), Positives = 147/402 (36%), Gaps = 53/402 (13%)
Query: 142 LTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDK 201
+ S + + V++EE + HK++ + S+S + + + EK K +
Sbjct: 171 ILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKR 230
Query: 202 EKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKE----------TER 251
+K +H++ +++R K++ +E + + N E S + E R
Sbjct: 231 KKKHRKNSRKHKKEKKKRKKSKKSASSESEAE--NLEAQPQSTVRPEEIPPIPENRFLMR 288
Query: 252 KSEGGKEKERLRDRDRERDRD----------------------KGKDRDRRRVKNGEHSW 289
KS +++ ++R+RER+R+ K K R RR + S
Sbjct: 289 KSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSR 348
Query: 290 DLDREK--------NREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLT 341
DR + +E + ++ SSGE K + K + + + K +T
Sbjct: 349 SRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERK-IT 407
Query: 342 TKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDD 401
+ S N + KE + +S I ++ K A S S S +
Sbjct: 408 DHRNVSESPNR-KNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKE 466
Query: 402 NSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRP 461
S S ++ + N E+++ S S G+D V E + + + R
Sbjct: 467 KSKSKERDS-KHNRNEEKRMRSRS--------KGRDHENVKEKEKQSDSKGKDQERSRSK 517
Query: 462 GSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDN 503
++ + D ++ + DR ++ IT+ +S N
Sbjct: 518 EKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYN 559
>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
Length = 2240
Score = 81.3 bits (199), Expect = 3e-15
Identities = 48/143 (33%), Positives = 81/143 (56%), Gaps = 3/143 (2%)
Query: 167 DRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARP 226
+R D KE+ Q EDR+ RE+++ + ++E +R RE +R R K +R
Sbjct: 2089 ERFDVGPKEKPLEEPDAQGRA-SEDRR-RERERGRNWSRERDWDRPREWDRHRDKDSSRD 2146
Query: 227 DNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGE 286
+ ++ NR+R+R+++R KE +R E + +ER RDR R+RDR + ++RDR + ++ E
Sbjct: 2147 WDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRE 2206
Query: 287 HSWD-LDREKNREHDKPEKKSAS 308
D DR K++E + K AS
Sbjct: 2207 RGRDRKDRSKSKESARDPKPEAS 2229
Score = 66.2 bits (160), Expect = 9e-11
Identities = 45/154 (29%), Positives = 75/154 (48%), Gaps = 7/154 (4%)
Query: 176 RSTSRDRKQKEELKEDRKPREKDKDKEKAKENGG-NRHREGERERAKARARP-DNERQKD 233
R+ + + +Q+E D P+EK ++ A+ +R RE ER R +R R D R+ D
Sbjct: 2079 RNQTFEGRQRERF--DVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWD 2136
Query: 234 RGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDR 293
R RD+DS R + R+ +++ER DR +E DR + + R+R R ++ D R
Sbjct: 2137 R---HRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSR 2193
Query: 294 EKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE 327
+ R+ DK + + S + +D K E
Sbjct: 2194 SRERDRDKARDRERGRDRKDRSKSKESARDPKPE 2227
Score = 65.9 bits (159), Expect = 1e-10
Identities = 49/154 (31%), Positives = 80/154 (51%), Gaps = 16/154 (10%)
Query: 201 KEKAKENGGNRHREGERERAKARARPDNERQKDRG---NRERDRDSERKKETERKSEGGK 257
+++ + + G + + E A+ RA D R+++RG +RERD D R+ + R + +
Sbjct: 2086 RQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSR 2145
Query: 258 E----KERLRDRDRERDRDKGK--DRDRRRVKNGEHS----WDLDREKNREHDKPEKKSA 307
+ +ER +RDRER+ D+GK DR R R +N E D DR ++RE D+ + +
Sbjct: 2146 DWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDR 2205
Query: 308 SSGEMSKKLSDGTFKDSKAETETEISTRASKSLT 341
G K S K+S + + E S RAS + T
Sbjct: 2206 ERGRDRKDRSKS--KESARDPKPEAS-RASDAGT 2236
Score = 43.5 bits (101), Expect = 7e-04
Identities = 38/164 (23%), Positives = 69/164 (42%), Gaps = 8/164 (4%)
Query: 213 REGERERAKARARPDNERQK-DRGNRER-----DRDSERKKETERKSEGGKEKERLRDRD 266
REG+ + + +R++ D G +E+ D ++ R+ E G+ R RD D
Sbjct: 2071 REGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWD 2130
Query: 267 RER--DRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
R R DR + KD R +N E S + DRE+ + K +S ++ D
Sbjct: 2131 RPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRSRERSRNRERERDRRRDRD 2190
Query: 325 KAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDS 368
++ + +A + K RSK+ R ++++ D+
Sbjct: 2191 RSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEASRASDA 2234
Score = 43.5 bits (101), Expect = 7e-04
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 26/143 (18%)
Query: 132 EKGEVKGRASLTSR---------SQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR 182
E+ + +GRAS R S+E D RE + K++ D +ERS +RDR
Sbjct: 2101 EEPDAQGRASEDRRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRN-RERSANRDR 2159
Query: 183 -------KQKEELKEDRKPREKDKDKEKAKENGGNRHREGE--RERAKARARPDNERQKD 233
K+ + +E + RE+++D+ + ++ +R R+ + R+R + R R D + K+
Sbjct: 2160 EREADRGKEWDRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKE 2219
Query: 234 RGNRERDRDSERKKETERKSEGG 256
+ K E R S+ G
Sbjct: 2220 SAR-------DPKPEASRASDAG 2235
Score = 32.0 bits (71), Expect = 2.0
Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 23/170 (13%)
Query: 374 NNEPNQETTTSEIGTKEANINSTSI--SDDNSASLRCENIQPNPTEKQKG----DSTSDA 427
+ EP T E ++ S S S SAS + +P +EK KG D TSD+
Sbjct: 96 SGEPTSCPATDAETASEGSVESASETRSGPQSASTAVKE-RPASSEKVKGGDDHDDTSDS 154
Query: 428 EGDAGPAGQDKSEVPETPEIPNELSSNIRRIP--RPGSARPAPPRVKRQDSMEALQMDRS 485
+ D E+ N L + P RP + R KR++ A +
Sbjct: 155 DSDG----------LTLKELQNRLRRKREQEPTERPLKGIQSRLRKKRREEGPAETVGSE 204
Query: 486 GSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEE 535
S TV V+ +N DQ VV A + S++E A ++++EE
Sbjct: 205 ASD-TVEGVLPSKQEPEN---DQGVVSQAGKDDRESKLEGKAAQDIKDEE 250
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 79.3 bits (194), Expect = 1e-14
Identities = 76/356 (21%), Positives = 151/356 (42%), Gaps = 25/356 (7%)
Query: 141 SLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDR---KQKEELKEDRKPREK 197
S + + L+ + E R + ED+ + + RS SR R + + + RK R +
Sbjct: 149 SYSDMKRALEKLDGTEVNGRKIRLVEDKPGSR-RRRSYSRSRSHSRSRSRSRHSRKSRSR 207
Query: 198 DKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGK 257
+ + +R R G R R+K+R+R + + R +E+ R ++K R GK
Sbjct: 208 SGSSKSSHSKSRSRSRSGSRSRSKSRSR---SQSRSRSKKEKSRSPSKEKSRSRSHSAGK 264
Query: 258 EKERLRDRDRERDRDK---GKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSK 314
+ + +D+ E+ ++ GK + R ++ S R + R ++ ++ S S G +
Sbjct: 265 SRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQE 324
Query: 315 KLSDGTFKDSKAETETEISTRA---SKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVS 371
K + + S++ + ++ +R+ S+S + K R ++ E R +KS S
Sbjct: 325 K----SLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR 380
Query: 372 GINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDA 431
G ++ + + +S+ KE S S S S S E+ + ++++ + +A +
Sbjct: 381 G--SKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQ 438
Query: 432 GPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGS 487
+ +S P +P+E S R SA R K + + RS S
Sbjct: 439 ETRSRSRSNSKSKPNLPSESRS------RSKSASKTRSRSKSRSRSASRSPSRSRS 488
Score = 73.6 bits (179), Expect = 6e-13
Identities = 71/294 (24%), Positives = 127/294 (43%), Gaps = 35/294 (11%)
Query: 137 KGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPRE 196
+ R S SRS+ +K+ +SR + R ++ + RS SR R +KE+ + K +
Sbjct: 197 RSRHSRKSRSRSGSSKS-SHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKS 255
Query: 197 KD----------KDKEKAKENGGNRHREGE---------RERAKARARPDNER--QKDRG 235
+ K K++A+E N G+ + ++K+R+R R ++ RG
Sbjct: 256 RSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRG 315
Query: 236 NRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREK 295
+ R R E+ R K R R R R + +DK K R R R ++ R +
Sbjct: 316 SVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES--------RSR 367
Query: 296 NREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSV-E 354
+R K E +S G + + K K +T+ S S+S++ + +S++S E
Sbjct: 368 SRSRSKSE-RSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQRE 426
Query: 355 GRKEDNISAKSLDSIVSGINNEPNQETTTSEIGTKEANINST---SISDDNSAS 405
GR E + + ++ +N ++ SE ++ + + T S S SAS
Sbjct: 427 GRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSAS 480
Score = 68.2 bits (165), Expect = 2e-11
Identities = 58/246 (23%), Positives = 112/246 (45%), Gaps = 34/246 (13%)
Query: 132 EKGEVKGRASLTSRSQELD--------NKNVREEESRV---HKN-------TEDRGDAEI 173
EK + ++ SRS+ D N NV + +SR HK+ +++R E
Sbjct: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE 312
Query: 174 KERSTSRDRKQKEELKEDRK-------PREKDKDKEKAKENGGNRHREGERERAKARARP 226
K S SR R Q++ L++ R R + + + K+K+ R R E R+++R+R
Sbjct: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRS 372
Query: 227 DNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGE 286
+ER + RG++ + KK ++K + + + R R ++R+ K +R GE
Sbjct: 373 KSERSRKRGSKRDSKAGSSKK--KKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
Query: 287 HSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRA-SKSLTTKTS 345
E + + +S S+ + L + SK+ ++T +++ S+S + S
Sbjct: 431 ------SENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPS 484
Query: 346 KRRSKN 351
+ RS++
Sbjct: 485 RSRSRS 490
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/185 (21%), Positives = 77/185 (41%), Gaps = 16/185 (8%)
Query: 120 SSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVRE---EESRVHKNTEDRGDAEIKER 176
S + ++R+ + + + R+ SRS+ D + R+ EESR + + ER
Sbjct: 322 SQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKS-----ER 376
Query: 177 STSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGN 236
S R K+ + +K +++D D+ +++ R +ER A+ +E + G
Sbjct: 377 SRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPS----RSVSKEREHAK----SESSQREGR 428
Query: 237 RERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKN 296
E + ++ R K K L R R + K R R + ++ S R ++
Sbjct: 429 GESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRS 488
Query: 297 REHDK 301
R H +
Sbjct: 489 RSHSR 493
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 79.0 bits (193), Expect = 1e-14
Identities = 57/219 (26%), Positives = 103/219 (47%), Gaps = 21/219 (9%)
Query: 145 RSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKA 204
R E +K+ ++ +S H + E D + ++S + + + + KE + R + + ++
Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71
Query: 205 KENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRD 264
+E RHR RER K+R+R ER+K R +R R+R R + ERK R+R
Sbjct: 72 RER---RHRSRSRERKKSRSR-SRERKKSR-SRSRERKKSRSRSRERK-------RRIRS 119
Query: 265 RDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
R R R R + + R R R ++ R++ + +KP + S S +S+ S F+
Sbjct: 120 RSRSRSRHRHRTRSRSRTRS------RSRDRKKRIEKPRRFSRS---LSRTPSPPPFRGR 170
Query: 325 KAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISA 363
+ + + K ++R K VE +K+ I+A
Sbjct: 171 NTAMDAQEALARRLERAKKLQEQREKEMVEKQKQQEIAA 209
Score = 57.8 bits (138), Expect = 3e-08
Identities = 41/174 (23%), Positives = 75/174 (43%), Gaps = 2/174 (1%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E KGR L S D +E +S ++ E + RS SR+RK+ +
Sbjct: 33 EHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRE 92
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
RK + + + +E+ K +R R+ R R+++R+R + + +R R R +RKK E+
Sbjct: 93 RK-KSRSRSRERKKSRSRSRERK-RRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEK 150
Query: 252 KSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKK 305
+ R R R+ D + E + L ++ +E + +K+
Sbjct: 151 PRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204
Score = 52.8 bits (125), Expect = 1e-06
Identities = 48/224 (21%), Positives = 94/224 (41%), Gaps = 23/224 (10%)
Query: 120 SSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTS 179
SS++ R E+ +GR+ SRS+E +++ SR K + R K RS S
Sbjct: 45 SSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS----RSRERKKSRSRSRERKKSRSRS 100
Query: 180 RDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRER 239
R+RK+ +RK R + + + ++ RHR R R++ R+R +R+R
Sbjct: 101 RERKKSRSRSRERKRRIRSRSRSRS------RHRHRTRSRSRTRSR----------SRDR 144
Query: 240 DRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREH 299
+ E+ + R R R+ D + R R K + + + + ++
Sbjct: 145 KKRIEKPRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMVEKQKQ 204
Query: 300 DKPEKKSASSG---EMSKKLSDGTFKDSKAETETEISTRASKSL 340
+ +A+ G ++ L+ GT + +++ +K+L
Sbjct: 205 QEIAAAAATGGSVLNVAALLASGTQVTPQIAMAAQMAALQAKAL 248
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 78.6 bits (192), Expect = 2e-14
Identities = 103/460 (22%), Positives = 202/460 (43%), Gaps = 51/460 (11%)
Query: 152 KNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKE-ELKEDRKPREKDKDKEKAKENGGN 210
+ +RE +S ++K G A ++ +S++ D K + ELK D + KA + N
Sbjct: 499 RKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDAN 558
Query: 211 RHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERD 270
+ R + ER+++R +ER+R+ ER+KE ER+ E K KE ++RD +D
Sbjct: 559 EIKS---------KRDEEERERERREKEREREREREKEKEREREKQKLKESEKERDSAKD 609
Query: 271 RDKGKDRDRRRVKNGE--HSWDLDREKNREHDKPEK------KSASSGEMSKKLSDGTFK 322
++KGK D R+ K E ++ +K +E K K +SA + K K
Sbjct: 610 KEKGKHDDGRK-KEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEK 668
Query: 323 DSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETT 382
SKAE E ++ R K L K K K + D + + + ++ I E Q+
Sbjct: 669 KSKAELE-DLRQRL-KDLEDKEKKENKKMA------DEDALRKIRAVEEQI--EYLQKKL 718
Query: 383 TSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVP 442
+EA ++ ++ ++ +NI+ ++K D+ + + Q +
Sbjct: 719 AMAKQEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLK 778
Query: 443 ETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSD 502
E E EL+ + + A+ V++ + E L G+G+ + T++
Sbjct: 779 EEKE---ELADQVLTLKTQVDAQLQV--VRKLEEKEHLLQSNIGTGEKELGLRTQA---- 829
Query: 503 NEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKH---GGLVKKILETKKDYEKLQQSPK 559
E + + +EAA QL++ ++ +EL +++ H +V+ + +KD +++ +
Sbjct: 830 LEMNKRKAMEAA-QLAD----DLKAQLELAQKKLHDFQDEIVENSVTKEKDMFNFKRAQE 884
Query: 560 PGEKERSLFESAWKKEK-----DIVSKEIEKLRTSIQTLC 594
+ R E+ K + +I+ +EI+ + + C
Sbjct: 885 DISRLRRKLETTKKPDNVPKCDEILMEEIKDYKARLTCPC 924
Score = 60.1 bits (144), Expect = 7e-09
Identities = 46/159 (28%), Positives = 80/159 (50%), Gaps = 15/159 (9%)
Query: 129 LAGEKGEVKGRASLTSRSQELDN--KNVREEESRVHKNTEDRGDAEIKERSTSRDR-KQK 185
L + ++ ++S + SQE N K+ R+EE R + E + E +ER ++R ++K
Sbjct: 536 LKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERE-REREKEKEREREK 594
Query: 186 EELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKD--------RGNR 237
++LKE K R+ KDKEK K + G + ++ K + E QK+ R
Sbjct: 595 QKLKESEKERDSAKDKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAP 654
Query: 238 ERDRDSERKKETERKSEGGKE--KERLRD-RDRERDRDK 273
+ RD + E+KS+ E ++RL+D D+E+ +K
Sbjct: 655 KEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENK 693
Score = 40.4 bits (93), Expect = 0.006
Identities = 89/385 (23%), Positives = 155/385 (40%), Gaps = 56/385 (14%)
Query: 311 EMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRS--KNSVEGRKEDNISAKSLDS 368
EM+ +L + E E + + +TT+ K + +++VE ++ + + S
Sbjct: 327 EMNAELEENKELAQNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQS 386
Query: 369 IVSGINNEPNQ------ETTTSEIGTKEANINSTSISDDNSASL----RCENIQPNPTEK 418
S + NE Q E T GT+ + + + + + SL R E IQ T
Sbjct: 387 QFSVLYNESLQLKAHLDEARTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDTLA 446
Query: 419 Q----------KGDSTSDAEGDAGPAGQDKSEVPETPEIPN-ELSSNIRRIPRPGSARPA 467
Q + + T A AGP ++ + + + N +L + R R R A
Sbjct: 447 QVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKR--KLREA 504
Query: 468 PPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEE-----DDQFVVEAAPQLSEMSE 522
Q + ++ RSGS S TE + E +D +A + S+
Sbjct: 505 ------QSDLNKTRL-RSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDA 557
Query: 523 IEMVTAVELEEEEKHGGLVKKILETKKDYEKLQ----QSPKPGEKERSLFESAWKKEKDI 578
E+ + + EE E+ ++ E +++ EK + Q K EKER +SA KEK
Sbjct: 558 NEIKSKRDEEERERERREKEREREREREKEKEREREKQKLKESEKER---DSAKDKEK-- 612
Query: 579 VSKEIEKLRTSIQTLCKSALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRI 638
K + + + + + + L K QE M+ L M+ S ++ + +Q
Sbjct: 613 -GKHDDGRKKEAEIIKQLKIELKKA----QESQKEMKLLLDMYRSAPKEQRDKVQLM--- 664
Query: 639 TDCAVEPLKAELAELEQLIKDQQDK 663
A + KAEL +L Q +KD +DK
Sbjct: 665 --AAEKKSKAELEDLRQRLKDLEDK 687
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 76.6 bits (187), Expect = 7e-14
Identities = 57/179 (31%), Positives = 85/179 (47%), Gaps = 29/179 (16%)
Query: 155 REEESRVHKNTEDRGDAEI-----KERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGG 209
RE E R +E D + + RS SRDR++KE K K EK KEKA+E
Sbjct: 1151 REMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEK---KEKAQEEPP 1207
Query: 210 NRHREGERERAKA--------------------RARPDNERQKDRGNRERDRDSERKKET 249
+ + + KA RA ER+K R +E + ER+KE
Sbjct: 1208 AKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEA 1267
Query: 250 ERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSAS 308
ER+ E+E+ R+ RERDR++ ++R+R R + + + DRE+ RE D+ + K S
Sbjct: 1268 ERERNRQLEREKRREHSRERDRERERERERDR-GDRDRDRERDRERGRERDRRDTKRHS 1325
Score = 70.9 bits (172), Expect = 4e-12
Identities = 41/109 (37%), Positives = 67/109 (61%), Gaps = 6/109 (5%)
Query: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNE 229
+AE ER+ R++++KE+ +E++K REK+ ++E+ ++ + RE RER + R R E
Sbjct: 1238 EAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERER---E 1294
Query: 230 RQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERD-RDKGKDR 277
R++DRG+R+RDR ER +E R+ + K R R R RD+G R
Sbjct: 1295 RERDRGDRDRDR--ERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 68.2 bits (165), Expect = 2e-11
Identities = 53/197 (26%), Positives = 90/197 (45%), Gaps = 46/197 (23%)
Query: 155 REEESRVHKNTEDRG-DAEIKERSTSRDRKQKEELKE---------DRKPREKDKDKEKA 204
RE+E V + +R + E +ER+ S +++++E DR+ +E+ K KEK
Sbjct: 1136 REQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKK 1195
Query: 205 KENGGNR---------------------------------HREGER-ERAKAR-ARPDNE 229
E +E ER ERAK R R +
Sbjct: 1196 SEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQ 1255
Query: 230 RQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSW 289
++++ RE++ + ER ++ ER+ +ER R+R+RER+RD+G DRDR R ++ E
Sbjct: 1256 EEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRG-DRDRDRERDRERGR 1314
Query: 290 DLDREKNREHDKPEKKS 306
+ DR + H + +S
Sbjct: 1315 ERDRRDTKRHSRSRSRS 1331
Score = 53.9 bits (128), Expect = 5e-07
Identities = 41/138 (29%), Positives = 69/138 (50%), Gaps = 20/138 (14%)
Query: 231 QKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWD 290
Q+++ R++ +ER++E ER+ E+E RD+ RE R + + RDRRR
Sbjct: 1135 QREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRR--------- 1185
Query: 291 LDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE--------TETEISTRASK--SL 340
+R K++E K EKK + E KL D F+ +KA T+++I + ++
Sbjct: 1186 KERAKSKE-KKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAER 1244
Query: 341 TTKTSKRRSKNSVEGRKE 358
+ KRR + E +KE
Sbjct: 1245 AKEREKRRKEQEEEEQKE 1262
Score = 51.6 bits (122), Expect = 2e-06
Identities = 41/205 (20%), Positives = 95/205 (46%), Gaps = 36/205 (17%)
Query: 179 SRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRE 238
+ R+Q+ ++E RE++ ++ + + R+ RE ++R+R + R+K+R +
Sbjct: 1133 AEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERA-KS 1191
Query: 239 RDRDSERKKETE------------RKSEG------------------GKEKERLRDRD-R 267
+++ SE+K++ + RK++ + ER ++R+ R
Sbjct: 1192 KEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKR 1251
Query: 268 ERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE 327
+++++ + ++R + E + L+REK REH + E+ E + D +D E
Sbjct: 1252 RKEQEEEEQKEREKEAERERNRQLEREKRREHSR-ERDRERERERERDRGD---RDRDRE 1307
Query: 328 TETEISTRASKSLTTKTSKRRSKNS 352
+ E + T + S+ RS+++
Sbjct: 1308 RDRERGRERDRRDTKRHSRSRSRST 1332
Score = 48.9 bits (115), Expect = 2e-05
Identities = 29/106 (27%), Positives = 54/106 (50%), Gaps = 5/106 (4%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
E+ E + QE + + RE+E+ +N + + K R SR+R ++ E + +
Sbjct: 1240 ERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLERE---KRREHSRERDRERERERE 1296
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNR 237
R ++D+D+E+ +E G R R + +++R+R R DRG R
Sbjct: 1297 RDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVR--DRGGR 1340
Score = 47.0 bits (110), Expect = 6e-05
Identities = 29/104 (27%), Positives = 58/104 (55%), Gaps = 12/104 (11%)
Query: 150 DNKNVREEESRVH------KNTEDRGDAEIKERSTSRDRKQKEELKEDRK---PREKDKD 200
D++ V++E R K +++ + E KER +R++ +L+ +++ RE+D++
Sbjct: 1231 DSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRE 1290
Query: 201 KEKAKENG-GNRHREGERERAKARARPDNERQKDRGNRERDRDS 243
+E+ +E G+R R+ ER+R + R R + R R +R R R +
Sbjct: 1291 RERERERDRGDRDRDRERDRERGRER--DRRDTKRHSRSRSRST 1332
Score = 45.4 bits (106), Expect = 2e-04
Identities = 58/303 (19%), Positives = 120/303 (39%), Gaps = 36/303 (11%)
Query: 118 KLSSDDAVRRVLAGEKGEVKGRASLTSR-SQELDNKNVREEESRVH------------KN 164
++S + +++ L ++ ++ R +R + EL+ + E+ +H ++
Sbjct: 130 EMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQS 189
Query: 165 TEDRGDAEIKERSTSRDRKQKEEL--KEDRKPREKDKDKEKAKENGGNRHREGERERAKA 222
+ +R + E+ S + EE +D KPR+ ++ + ++ + EG +
Sbjct: 190 SLERPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPA--- 246
Query: 223 RARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRV 282
+ E ++ +R ++R +TE + E +E+E D + E D + K R+ +
Sbjct: 247 ----EEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEE-DDEEEEGDDEGQKSREAPIL 301
Query: 283 KNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTT 342
K + + E E+ S E G F S+ E R +
Sbjct: 302 KEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLERGGRFTRSQEEARKSHLARQQQEKEM 361
Query: 343 KTS-----KRRSKNSVEGRKEDNISA--------KSLDSIVSGINNEPNQETTTSEIGTK 389
KT+ + R S +G KE + S + S+V+ ++E T + TK
Sbjct: 362 KTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDRKKASLVALPEQTASEEETPPPLLTK 421
Query: 390 EAN 392
EA+
Sbjct: 422 EAS 424
Score = 45.4 bits (106), Expect = 2e-04
Identities = 30/113 (26%), Positives = 58/113 (51%), Gaps = 9/113 (7%)
Query: 136 VKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPR 195
V+ A R++E + + +E+E K E + E + R R+++++ + DR+ R
Sbjct: 1235 VQKEAERAERAKEREKRR-KEQEEEEQKEREKEAERE-RNRQLEREKRREHSRERDRE-R 1291
Query: 196 EKDKDKEKAKENGGNRHREGERERAKARARPD---NERQKDRGNRERDRDSER 245
E+++++++ +R RE +RER + R R D + R + R RDR R
Sbjct: 1292 ERERERDRGDR---DRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 36.2 bits (82), Expect = 0.10
Identities = 74/397 (18%), Positives = 148/397 (37%), Gaps = 74/397 (18%)
Query: 177 STSRDRKQKEELKEDRKPRE--KDKDKEKAKENGGNRHREGER----ERAKARARPDNER 230
STSR + EE+ D KP + + D + A E G + G++ +R K +N +
Sbjct: 54 STSRKMAELEEVTLDGKPLQALRVTDLKAALEQRGLA-KSGQKSALVKRLKGALMLENLQ 112
Query: 231 QKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWD 290
+ + +S+ +E + S + E+ ++ R+R
Sbjct: 113 KHSTPHAAFQPNSQIGEEMSQNSFIKQYLEKQQELLRQR--------------------- 151
Query: 291 LDREKNREHDKPEKKSASSGEMSK-----KLSDGTFKDSKAETETEISTRASKSLTTKTS 345
L+RE + E + S EM L F+ S E E+S + + ++ +
Sbjct: 152 LEREAREAAELEEASAESEDEMIHPEGVASLLPPDFQSSLERPELELSRHSPRKSSSISE 211
Query: 346 KRRSKNSVEGRKEDNISAKSLDSIVSGIN--NEPNQETTTSEIGTKEANINSTSISDDNS 403
++ + + RK + S++ + + ++ ++P +E E ++ + +
Sbjct: 212 EKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRAD------- 264
Query: 404 ASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGS 463
N++ TE+++ + + E D G D+ + I E IPR
Sbjct: 265 -----RNLK---TEEEEEEEEEEEEDDEEEEGDDEGQKSREAPILKEFKEEGEEIPRVKP 316
Query: 464 ARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEI 523
R K + S E ++R G +SH + ++ E
Sbjct: 317 EEMMDERPKTR-SQEQEVLERGGRFTRSQEEARKSHLARQQQ----------------EK 359
Query: 524 EMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSPKP 560
EM T LEEEE+ +++ + ++ +SP P
Sbjct: 360 EMKTTSPLEEEERE-------IKSSQGLKEKSKSPSP 389
Score = 32.7 bits (73), Expect = 1.2
Identities = 71/354 (20%), Positives = 131/354 (37%), Gaps = 42/354 (11%)
Query: 326 AETETEISTRASKSLTTK-TSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTS 384
A+ T + R + ++ TS+ RS++ R + S KSL VS ++++TS
Sbjct: 615 AQARTHANPRGRPKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVS-------RDSSTS 667
Query: 385 EIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQDKS-EVPE 443
TK+ + + CE P E+ STS + A Q +S E
Sbjct: 668 YTETKDPSSGQEVATPPVPQLQVCE-----PKER---TSTSSSSVQARRLSQPESAEKHV 719
Query: 444 TPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVITESH---- 499
T + E S P+ A A P Q Q + + + + E
Sbjct: 720 TQRLQPERGS-----PKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHTVEEKEEVTM 774
Query: 500 -NSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKHGGLVKKILETKKDYEKLQQSP 558
S+N ++ P ++S + +EE+K L K + P
Sbjct: 775 DTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRKISVVSATKGVP 834
Query: 559 ---------KPGEKERSLFESAWKKEKDIVSKEIEKLRTSIQTLCKSALPLGKIMDYIQE 609
+PG K R +A ++K +S E L++ I + K ++D +
Sbjct: 835 AGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDI-KPLAGQEAVVDLHAD 893
Query: 610 DVDAMQNELQMWHSENRQHAEALQQEQRITDCAVEPLKAELAELEQLIKDQQDK 663
D ++E + + ++ H + L +I + + AE E Q +++++K
Sbjct: 894 DSRISEDETER-NGDDGTHDKGL----KICRTVTQVVPAEGQENGQREEEEEEK 942
Score = 30.4 bits (67), Expect = 5.7
Identities = 27/112 (24%), Positives = 43/112 (38%), Gaps = 6/112 (5%)
Query: 109 QIIGKCCLNKLSSDDAVRRVLAGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDR 168
QI+ K + + +R E+ E K R R + N+ + E+ R H DR
Sbjct: 1233 QIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERER---NRQLEREKRREHSRERDR 1289
Query: 169 GDAEIKERSTS---RDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGER 217
+ER RDR++ E +R R+ + + R R G R
Sbjct: 1290 ERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTPVRDRGGRR 1341
Score = 30.0 bits (66), Expect = 7.5
Identities = 40/159 (25%), Positives = 57/159 (35%), Gaps = 23/159 (14%)
Query: 216 ERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRD--RERDRDK 273
E RA P + R K + R S + R + R R + RD
Sbjct: 556 EGRRASHTLLPSH-RLKQSADSSSSRSSSSSSSSSRSRSRSPDSSGSRSHSPLRSKQRDV 614
Query: 274 GKDR----DRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAE-T 328
+ R R R K G S R ++R + ++S K LS G +DS T
Sbjct: 615 AQARTHANPRGRPKMGSRSTSESRSRSRSRSR-----SASSNSRKSLSPGVSRDSSTSYT 669
Query: 329 ET-------EISTRASKSLTTKTSKRR---SKNSVEGRK 357
ET E++T L K R S +SV+ R+
Sbjct: 670 ETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARR 708
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 75.9 bits (185), Expect = 1e-13
Identities = 57/231 (24%), Positives = 112/231 (48%), Gaps = 26/231 (11%)
Query: 144 SRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKEDRKPREKDKDKEK 203
S + E K EEE R+ + + ++K +K+ E+ + RE++K++E+
Sbjct: 456 SAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERER 515
Query: 204 AKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLR 263
KE +E E+ER K ER+KDR ER ++ E++ E E++ + EKER +
Sbjct: 516 EKE----LEKEQEQEREK-------EREKDR---ERQQEKEKELEKEQEKQREMEKERKQ 561
Query: 264 DRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKD 323
++++E +R K K+++ +++K E +L++E+ + +K E + + M +
Sbjct: 562 EKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVE--------- 612
Query: 324 SKAETETEISTRASKSLTTKTSKRRSKNS--VEGRKEDNISAKSLDSIVSG 372
K E+E + T + S R K + V E ++ +++SG
Sbjct: 613 -KQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSG 662
Score = 60.1 bits (144), Expect = 7e-09
Identities = 52/197 (26%), Positives = 89/197 (45%), Gaps = 20/197 (10%)
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
R+ E E+A++ R E +R A A + G E+ E +E ER
Sbjct: 450 RQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERER 509
Query: 252 KSEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDK-----PEKKS 306
+ E +EKE +++++ER++++ KDR+R++ K E + ++EK RE +K EK+
Sbjct: 510 EKEREREKELEKEQEQEREKEREKDRERQQEK--EKELEKEQEKQREMEKERKQEKEKEL 567
Query: 307 ASSGEMSKKLSDGTFKDSKAETETEISTRASK------SLTTKTSKRRSKNS-------V 353
E K+L ++ + E E E K +L K+ S+NS V
Sbjct: 568 ERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPV 627
Query: 354 EGRKEDNISAKSLDSIV 370
R++ N S K +V
Sbjct: 628 FTRQDSNRSEKEATPVV 644
Score = 54.3 bits (129), Expect = 4e-07
Identities = 36/154 (23%), Positives = 70/154 (45%), Gaps = 3/154 (1%)
Query: 211 RHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERLRDRDRERD 270
R ++ E A RAR E ++ R +R K + + G EK+ + RER+
Sbjct: 449 RRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERE 508
Query: 271 RDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAETET 330
R+K ++R++ K E + +REK+RE + ++K + ++ + K+ K E E
Sbjct: 509 REKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREME---KERKQEKEK 565
Query: 331 EISTRASKSLTTKTSKRRSKNSVEGRKEDNISAK 364
E+ + K + K + K ++ + + K
Sbjct: 566 ELERQKEKEKELQKMKEQEKECELEKEREKLEEK 599
Score = 48.1 bits (113), Expect = 3e-05
Identities = 41/160 (25%), Positives = 71/160 (44%), Gaps = 15/160 (9%)
Query: 115 CLNKLSSDDAVRRVL----AGEKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGD 170
C KL D +L + E+ + R R +EL+ + +E E K+ E + +
Sbjct: 481 CAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQE 540
Query: 171 AEI-------KERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKAR 223
E K+R ++RKQ++E KE + +EK+K+ +K KE E ERE+ + +
Sbjct: 541 KEKELEKEQEKQREMEKERKQEKE-KELERQKEKEKELQKMKEQEKECELEKEREKLEEK 599
Query: 224 ARPDNERQKDRGNRERDRDSERKKET---ERKSEGGKEKE 260
P + ++ +S K+E R+ EKE
Sbjct: 600 IEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKE 639
Score = 38.1 bits (87), Expect = 0.027
Identities = 26/127 (20%), Positives = 51/127 (40%)
Query: 132 EKGEVKGRASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTSRDRKQKEELKED 191
EK K R + +EL+ + ++ E + E + E ++ +K KE+ KE
Sbjct: 528 EKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKEC 587
Query: 192 RKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETER 251
+E++K +EK + N E++ ++ + E R + R E
Sbjct: 588 ELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHET 647
Query: 252 KSEGGKE 258
+ E G +
Sbjct: 648 EPESGSQ 654
Score = 37.7 bits (86), Expect = 0.036
Identities = 54/294 (18%), Positives = 107/294 (36%), Gaps = 37/294 (12%)
Query: 374 NNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQ----KGDSTSDAEG 429
+N P + + + N + +D+ S + I P+ + KG S + G
Sbjct: 342 SNSPKENNSEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQERG 401
Query: 430 DAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGK 489
+ S +P P++ + R PG P P + + D E + R +
Sbjct: 402 TS-------SHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSE 454
Query: 490 TVSNVITESHNSDNEEDDQF--------------------VVEAAPQLSEMSEIEMVTAV 529
+S + + EE+ + ++E P E+ E E
Sbjct: 455 -ISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKER 513
Query: 530 ELEEEEKHGGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVSKEIEKLRTS 589
E E+E + ++ E +KD E+ Q+ K EKE+ K+ K KE+E+ +
Sbjct: 514 EREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEK 573
Query: 590 IQTLCK-----SALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQEQRI 638
+ L K L K + ++E ++ + L+ + ++E+ +
Sbjct: 574 EKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPV 627
Score = 32.0 bits (71), Expect = 2.0
Identities = 60/303 (19%), Positives = 113/303 (37%), Gaps = 35/303 (11%)
Query: 146 SQELDNKNVREEESRVHKNTEDRGDAEIK-ERSTSRDRKQKEELKEDRKPREKDKDKEKA 204
SQ ++V + K E R + + TSR KE ++ +P EK K +
Sbjct: 917 SQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIE---RPEEKPKKEGFI 973
Query: 205 KENGGNRHREGERERAKAR--ARPDNERQKDRGNRERDRDSERKKETERKSEGGKEKERL 262
+ + G + + + +++ R RP + R+++ +R R KK R
Sbjct: 974 RSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLR----------- 1022
Query: 263 RDRDRERDRDKGKDRDRRRVKNGEHSWDLDREKNREHDKPEKKSASSGEMSKKLSDGTFK 322
D ++R++R+ K GE + + + + +K EKK +
Sbjct: 1023 ---------DMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQP 1073
Query: 323 DSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKE-DNISAKSLDSIVSGINNEPNQET 381
S I A K +T+T+ K S + K + +S ++ V +N +
Sbjct: 1074 QS---VPPPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAP 1130
Query: 382 TTSEIGTKEANINSTSISD----DNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQD 437
E E I+ + + D+ +++ E+ P P K D D G G+
Sbjct: 1131 VVKEEKQPEKVISKDLVIERPRPDSRPAVKKESTLP-PRTYWKEARERDWFPDQGYRGRG 1189
Query: 438 KSE 440
+ E
Sbjct: 1190 RGE 1192
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 75.1 bits (183), Expect = 2e-13
Identities = 87/375 (23%), Positives = 156/375 (41%), Gaps = 54/375 (14%)
Query: 121 SDDAVRRVLAGEKGEVKG-RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTS 179
SDD + + E+GE++ R +T R N R E+S + ED D+ +
Sbjct: 4 SDDRDSKRDSLEEGELRDHRMEITIR-----NSPYRREDSMEDRGEED--DSLAIKPPQQ 56
Query: 180 RDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKD----RG 235
RK+K ++D K +EK + K KE R + E+ KAR + +++++
Sbjct: 57 MSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHS 116
Query: 236 NRERDR--DSERKKETERK-SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEH----- 287
RERDR ERK+E ERK E KE+ ++R+R R ++ K+R+ RR + H
Sbjct: 117 RRERDRLEQLERKRERERKMREQQKEQREQKERER-RAEERRKEREARREVSAHHRTMRE 175
Query: 288 ---------SWDL-------------DREKNREHDKPEKKSASSGEMSKKLSDGTFKDSK 325
W D K + +K E++ S + +SD K S
Sbjct: 176 DYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD--LQDISDSERKTSS 233
Query: 326 AETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSE 385
AE+ + S S+ + + + S E+ + + +G N+E E + E
Sbjct: 234 AESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 293
Query: 386 IGTKEANINSTSISDDN-----SASLRCENIQPNPTEKQKGDSTSDA----EGDAGPAGQ 436
+ +E + + ++++ + ++ + E++ G+ T + EGD P
Sbjct: 294 VSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSP 353
Query: 437 DKSEVPETPEIPNEL 451
S + E+P L
Sbjct: 354 ALSPIELKQELPKYL 368
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 74.3 bits (181), Expect = 3e-13
Identities = 93/387 (24%), Positives = 162/387 (41%), Gaps = 65/387 (16%)
Query: 120 SSDDAVRRVLAGEKGEVKG-RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERST 178
+SDD + + E+GE++ R +T R N R E+S + ED D+ +
Sbjct: 37 NSDDRDSKRDSLEEGELRDHRMEITIR-----NSPYRREDSMEDRGEED--DSLAIKPPQ 89
Query: 179 SRDRKQKEELKEDRKPREKDKDKEKAKENGGN---RHREGERERAKA------RARPDNE 229
RK+K ++D K +EK + + + E G + + +E E ER K +AR + E
Sbjct: 90 QMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWE 149
Query: 230 RQKDR------GNRERDR--DSERKKETERK-SEGGKEKERLRDRDRERDRDKGKDRDRR 280
RQK R RERDR ERK+E ERK E KE+ ++R+R R ++ K+R+ R
Sbjct: 150 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER-RAEERRKEREAR 208
Query: 281 RVKNGEH--------------SWDL-------------DREKNREHDKPEKKSASSGEMS 313
R + H W D K + +K E++ S
Sbjct: 209 REVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD--L 266
Query: 314 KKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGI 373
+ +SD K S AE+ + S S+ + + + S E+ + + +G
Sbjct: 267 QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGS 326
Query: 374 NNEPNQETTTSEIGTKEANINSTSISDDN-----SASLRCENIQPNPTEKQKGDSTSDA- 427
N+E E + E+ +E + + ++++ + ++ + E++ G+ T +
Sbjct: 327 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSS 386
Query: 428 ---EGDAGPAGQDKSEVPETPEIPNEL 451
EGD P S + E+P L
Sbjct: 387 ALTEGDYVPDSPALSPIELKQELPKYL 413
Score = 67.8 bits (164), Expect = 3e-11
Identities = 77/408 (18%), Positives = 161/408 (39%), Gaps = 56/408 (13%)
Query: 170 DAEIKERSTSRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHR---------------- 213
D ++E+ +++++K E+K + ++D ++ +E HR
Sbjct: 14 DEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRNSPYRREDSM 73
Query: 214 --EGERERAKARARPDNERQKDRGNRERD-RDSERKKETERKSEGGKEKERLRDRDRERD 270
GE + + A P +K++ + +D + E+++ +EGGK R+++++RE +
Sbjct: 74 EDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKH-ARVKEKEREHE 132
Query: 271 RDKGKDRDRRRVKNGEHSWDLD--REKNREHDKPEKKSASSGEMSKKLSDGTFKDSKAET 328
R K R R W+ RE REH + E+ E ++ + K +
Sbjct: 133 RRK---RHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQR 189
Query: 329 ETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTSEIGT 388
E + R ++ + RR ++ ++ S K S S P +E G
Sbjct: 190 EQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGR 249
Query: 389 KE------------ANINSTSISDDNSASLRCENIQPNPTEKQKGDSTSDAEGDAGPAGQ 436
K +++ S S+ ++S + + +++ + + E + + +
Sbjct: 250 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 309
Query: 437 DKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQMDRSGSGKTVSNVIT 496
+ E E E E SN + A + + S E + D + V+
Sbjct: 310 SEEEEEEEEEEEEETGSN---------SEEASEQSAEEVSEEEMSEDEERENENHLLVVP 360
Query: 497 ESH----NSDNEEDDQFVVEAAPQLSEMSEIEMV------TAVELEEE 534
ES + ++EE ++ V E PQ S ++E + V + +EL++E
Sbjct: 361 ESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 408
Score = 33.1 bits (74), Expect = 0.88
Identities = 33/174 (18%), Positives = 77/174 (44%), Gaps = 13/174 (7%)
Query: 470 RVKRQDSMEALQMDRSGSGKTVSNVI---TESHNSDNEEDDQFVVEAAPQLSEMSEIEMV 526
R ++DS+E ++ T+ N +S EEDD ++ Q+S ++
Sbjct: 41 RDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHR 100
Query: 527 TAVELEEEEKH------GGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVS 580
+ +E+ +H GG ++ E ++++E+ ++ + +K R +E +K +++
Sbjct: 101 KDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWER--QKRREMAR 158
Query: 581 KEIEKLRTSIQTLCKSALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQ 634
+ + R ++ L + K+ + Q+ Q E + E R+ EA ++
Sbjct: 159 EHSRRERDRLEQLERKRERERKMRE--QQKEQREQKERERRAEERRKEREARRE 210
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 73.9 bits (180), Expect = 5e-13
Identities = 86/376 (22%), Positives = 156/376 (41%), Gaps = 54/376 (14%)
Query: 120 SSDDAVRRVLAGEKGEVKGRA-SLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERST 178
+SDD + + E+GE++ +T R N R E+S + ED D+ +
Sbjct: 37 NSDDRDSKRDSLEEGELRDHCMEITIR-----NSPYRREDSMEDRGEED--DSLAIKPPQ 89
Query: 179 SRDRKQKEELKEDRKPREKDKDKEKAKENGGNRHREGERERAKARARPDNERQKD----R 234
RK+K ++D K +EK + K KE R + E+ KAR + +++++
Sbjct: 90 QMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREH 149
Query: 235 GNRERDR--DSERKKETERK-SEGGKEKERLRDRDRERDRDKGKDRDRRRVKNGEH---- 287
RERDR ERK+E ERK E KE+ ++R+R R ++ K+R+ RR + H
Sbjct: 150 SRRERDRLEQLERKRERERKMREQQKEQREQKERER-RAEERRKEREARREVSAHHRTMR 208
Query: 288 ----------SWDL-------------DREKNREHDKPEKKSASSGEMSKKLSDGTFKDS 324
W D K + +K E++ S + +SD K S
Sbjct: 209 EDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD--LQDISDSERKTS 266
Query: 325 KAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGINNEPNQETTTS 384
AE+ + S S+ + + + S E+ + + +G N+E E +
Sbjct: 267 SAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAE 326
Query: 385 EIGTKEANINSTSISDDN-----SASLRCENIQPNPTEKQKGDSTSDA----EGDAGPAG 435
E+ +E + + ++++ + ++ + E++ G+ T + EGD P
Sbjct: 327 EVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDS 386
Query: 436 QDKSEVPETPEIPNEL 451
S + E+P L
Sbjct: 387 PALSPIELKQELPKYL 402
Score = 42.7 bits (99), Expect = 0.001
Identities = 62/355 (17%), Positives = 123/355 (34%), Gaps = 27/355 (7%)
Query: 196 EKDKDKEKAKEN---GGNRHREGERERAKARARPDNERQKDRGNRERDRDSERKKETERK 252
EKD K K + R +E E + R + ++R R + E + E +
Sbjct: 4 EKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIR 63
Query: 253 SEGGKEKERLRDRDRERD----------RDKGKDRDRRRVKNGEHSWDLDREKNREHDKP 302
+ + ++ + DR E D K K R+ K E +EK REH++
Sbjct: 64 NSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERR 123
Query: 303 EKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNIS 362
++ + ++ + + E E S R L KR + + ++++
Sbjct: 124 KRHREEQDKARREWE----RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQRE 179
Query: 363 AKSLDSIVSGINNEPNQETTTSEIGTKEANINSTSISDDNSASLRCENIQPNPTEKQKGD 422
K +E +E + + ++ +D S ++ + +P +
Sbjct: 180 QKE--------RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPR-- 229
Query: 423 STSDAEGDAGPAGQDKSEVPETPEIPNELSSNIRRIPRPGSARPAPPRVKRQDSMEALQM 482
+ P ++K E + ++S + R+ S+ ++ E +
Sbjct: 230 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 289
Query: 483 DRSGSGKTVSNVITESHNSDNEEDDQFVVEAAPQLSEMSEIEMVTAVELEEEEKH 537
+ GS S E + EE EA+ Q +E E ++ E E E H
Sbjct: 290 EEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENH 344
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 73.9 bits (180), Expect = 5e-13
Identities = 93/386 (24%), Positives = 161/386 (41%), Gaps = 65/386 (16%)
Query: 121 SDDAVRRVLAGEKGEVKG-RASLTSRSQELDNKNVREEESRVHKNTEDRGDAEIKERSTS 179
SDD + + E+GE++ R +T R N R E+S + ED D+ +
Sbjct: 4 SDDRDSKRDSLEEGELRDHRMEITIR-----NSPYRREDSMEDRGEED--DSLAIKPPQQ 56
Query: 180 RDRKQKEELKEDRKPREKDKDKEKAKENGGN---RHREGERERAKA------RARPDNER 230
RK+K ++D K +EK + + + E G + + +E E ER K +AR + ER
Sbjct: 57 MSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWER 116
Query: 231 QKDR------GNRERDR--DSERKKETERK-SEGGKEKERLRDRDRERDRDKGKDRDRRR 281
QK R RERDR ERK+E ERK E KE+ ++R+R R ++ K+R+ RR
Sbjct: 117 QKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER-RAEERRKEREARR 175
Query: 282 VKNGEH--------------SWDL-------------DREKNREHDKPEKKSASSGEMSK 314
+ H W D K + +K E++ S +
Sbjct: 176 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSD--LQ 233
Query: 315 KLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNISAKSLDSIVSGIN 374
+SD K S AE+ + S S+ + + + S E+ + + +G N
Sbjct: 234 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 293
Query: 375 NEPNQETTTSEIGTKEANINSTSISDDN-----SASLRCENIQPNPTEKQKGDSTSDA-- 427
+E E + E+ +E + + ++++ + ++ + E++ G+ T +
Sbjct: 294 SEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSA 353
Query: 428 --EGDAGPAGQDKSEVPETPEIPNEL 451
EGD P S + E+P L
Sbjct: 354 LTEGDYVPDSPALSPIELKQELPKYL 379
Score = 33.1 bits (74), Expect = 0.88
Identities = 33/174 (18%), Positives = 77/174 (44%), Gaps = 13/174 (7%)
Query: 470 RVKRQDSMEALQMDRSGSGKTVSNVI---TESHNSDNEEDDQFVVEAAPQLSEMSEIEMV 526
R ++DS+E ++ T+ N +S EEDD ++ Q+S ++
Sbjct: 7 RDSKRDSLEEGELRDHRMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHR 66
Query: 527 TAVELEEEEKH------GGLVKKILETKKDYEKLQQSPKPGEKERSLFESAWKKEKDIVS 580
+ +E+ +H GG ++ E ++++E+ ++ + +K R +E +K +++
Sbjct: 67 KDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRHREEQDKARREWER--QKRREMAR 124
Query: 581 KEIEKLRTSIQTLCKSALPLGKIMDYIQEDVDAMQNELQMWHSENRQHAEALQQ 634
+ + R ++ L + K+ + Q+ Q E + E R+ EA ++
Sbjct: 125 EHSRRERDRLEQLERKRERERKMRE--QQKEQREQKERERRAEERRKEREARRE 176
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.125 0.333
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,462,674
Number of Sequences: 37866
Number of extensions: 1332900
Number of successful extensions: 28128
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 638
Number of HSP's successfully gapped in prelim test: 1025
Number of HSP's that attempted gapping in prelim test: 7212
Number of HSP's gapped (non-prelim): 8194
length of query: 691
length of database: 18,247,518
effective HSP length: 109
effective length of query: 582
effective length of database: 14,120,124
effective search space: 8217912168
effective search space used: 8217912168
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.