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Search of human proteins with 199559805
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|199559805 phostensin [Homo sapiens]
(613 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|145386517 phostensin [Homo sapiens] 1239 0.0
gi|199559805 phostensin [Homo sapiens] 1239 0.0
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 82 1e-15
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi... 82 1e-15
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 60 5e-09
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 58 3e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 58 3e-08
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 57 5e-08
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 57 7e-08
gi|116292174 fidgetin-like 2 [Homo sapiens] 57 7e-08
gi|148746195 trichohyalin [Homo sapiens] 56 8e-08
gi|44890059 involucrin [Homo sapiens] 55 2e-07
gi|210032580 SET domain containing 1B [Homo sapiens] 54 6e-07
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 52 1e-06
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 52 1e-06
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 1e-06
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 52 1e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 51 4e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 51 4e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 51 4e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 51 4e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 51 4e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 51 4e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 51 4e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 51 4e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 51 4e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 50 6e-06
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 50 6e-06
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 50 6e-06
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 50 8e-06
>gi|145386517 phostensin [Homo sapiens]
Length = 613
Score = 1239 bits (3205), Expect = 0.0
Identities = 613/613 (100%), Positives = 613/613 (100%)
Query: 1 MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSP 60
MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSP
Sbjct: 1 MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSP 60
Query: 61 VLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEAR 120
VLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEAR
Sbjct: 61 VLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEAR 120
Query: 121 ERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVG 180
ERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVG
Sbjct: 121 ERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVG 180
Query: 181 DRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHK 240
DRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHK
Sbjct: 181 DRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHK 240
Query: 241 WRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLT 300
WRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLT
Sbjct: 241 WRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLT 300
Query: 301 REAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPE 360
REAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPE
Sbjct: 301 REAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPE 360
Query: 361 SAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEA 420
SAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEA
Sbjct: 361 SAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEA 420
Query: 421 VELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSV 480
VELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSV
Sbjct: 421 VELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSV 480
Query: 481 PPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKI 540
PPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKI
Sbjct: 481 PPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKI 540
Query: 541 SFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGL 600
SFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGL
Sbjct: 541 SFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGL 600
Query: 601 RTKALIVDESCRR 613
RTKALIVDESCRR
Sbjct: 601 RTKALIVDESCRR 613
>gi|199559805 phostensin [Homo sapiens]
Length = 613
Score = 1239 bits (3205), Expect = 0.0
Identities = 613/613 (100%), Positives = 613/613 (100%)
Query: 1 MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSP 60
MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSP
Sbjct: 1 MATIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSP 60
Query: 61 VLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEAR 120
VLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEAR
Sbjct: 61 VLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEAR 120
Query: 121 ERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVG 180
ERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVG
Sbjct: 121 ERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVG 180
Query: 181 DRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHK 240
DRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHK
Sbjct: 181 DRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHK 240
Query: 241 WRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLT 300
WRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLT
Sbjct: 241 WRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLT 300
Query: 301 REAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPE 360
REAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPE
Sbjct: 301 REAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPE 360
Query: 361 SAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEA 420
SAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEA
Sbjct: 361 SAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEA 420
Query: 421 VELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSV 480
VELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSV
Sbjct: 421 VELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSV 480
Query: 481 PPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKI 540
PPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKI
Sbjct: 481 PPATPATPTSPATVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKI 540
Query: 541 SFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGL 600
SFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGL
Sbjct: 541 SFSETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGL 600
Query: 601 RTKALIVDESCRR 613
RTKALIVDESCRR
Sbjct: 601 RTKALIVDESCRR 613
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
Length = 678
Score = 82.0 bits (201), Expect = 1e-15
Identities = 60/164 (36%), Positives = 81/164 (49%), Gaps = 21/164 (12%)
Query: 437 APTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPAT------PATPTS 490
AP A + P P +R + + G R +TFTV P+R P T
Sbjct: 405 APQAAKLPYLPHPARPLHPARPGCVAELQPRGSNTFTVVPKRK--PGTLQDQHFSQANRE 462
Query: 491 PATVDAAVPGAG-------KKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKISFS 543
P +A A KKRYPT EI V+GGYL L +SCL K R K++KISF+
Sbjct: 463 PRPREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSR--KKMKISFN 520
Query: 544 ETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEE 587
+ +L+TT++YPSESS L E EV + ++EE+EE
Sbjct: 521 DKSLQTTFEYPSESS----LEQEEEVDQQEEEEEEEEEEEEEEE 560
Score = 43.1 bits (100), Expect = 7e-04
Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 14/60 (23%)
Query: 425 PPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRS-------GHTFTVNPR 477
PPPP P +PP P P AP PP P G + G RRS ++FTV+PR
Sbjct: 97 PPPPPPPAPPRPPPAAPSPPAAP-------GPRGGGASPGARRSDFLQKTGSNSFTVHPR 149
Score = 34.3 bits (77), Expect = 0.35
Identities = 41/135 (30%), Positives = 47/135 (34%), Gaps = 29/135 (21%)
Query: 377 EAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPP 436
EAE+ G R L+ VP G LR +E P P P PP
Sbjct: 4 EAERRRGGGAAGA-RLLERYRRVP--------GVRALRADSVLIIETVPGFP----PAPP 50
Query: 437 APTAPQ-----------PPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPATP 485
AP A Q PPG +SRL ++ APRR G P PP P
Sbjct: 51 APGAAQIRAAEVLVYGAPPGR--VSRL---LERFDPPAAPRRRGSPERARPPPPPPPPAP 105
Query: 486 ATPTSPATVDAAVPG 500
P A A PG
Sbjct: 106 PRPPPAAPSPPAAPG 120
>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
sapiens]
Length = 650
Score = 82.0 bits (201), Expect = 1e-15
Identities = 60/164 (36%), Positives = 81/164 (49%), Gaps = 21/164 (12%)
Query: 437 APTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPAT------PATPTS 490
AP A + P P +R + + G R +TFTV P+R P T
Sbjct: 405 APQAAKLPYLPHPARPLHPARPGCVAELQPRGSNTFTVVPKRK--PGTLQDQHFSQANRE 462
Query: 491 PATVDAAVPGAG-------KKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKISFS 543
P +A A KKRYPT EI V+GGYL L +SCL K R K++KISF+
Sbjct: 463 PRPREAEEEEASCLLGPTLKKRYPTVHEIEVIGGYLALQKSCLTKAGSSR--KKMKISFN 520
Query: 544 ETALETTYQYPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEE 587
+ +L+TT++YPSESS L E EV + ++EE+EE
Sbjct: 521 DKSLQTTFEYPSESS----LEQEEEVDQQEEEEEEEEEEEEEEE 560
Score = 43.1 bits (100), Expect = 7e-04
Identities = 24/60 (40%), Positives = 29/60 (48%), Gaps = 14/60 (23%)
Query: 425 PPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRS-------GHTFTVNPR 477
PPPP P +PP P P AP PP P G + G RRS ++FTV+PR
Sbjct: 97 PPPPPPPAPPRPPPAAPSPPAAP-------GPRGGGASPGARRSDFLQKTGSNSFTVHPR 149
Score = 34.3 bits (77), Expect = 0.35
Identities = 41/135 (30%), Positives = 47/135 (34%), Gaps = 29/135 (21%)
Query: 377 EAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPP 436
EAE+ G R L+ VP G LR +E P P P PP
Sbjct: 4 EAERRRGGGAAGA-RLLERYRRVP--------GVRALRADSVLIIETVPGFP----PAPP 50
Query: 437 APTAPQ-----------PPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPATP 485
AP A Q PPG +SRL ++ APRR G P PP P
Sbjct: 51 APGAAQIRAAEVLVYGAPPGR--VSRL---LERFDPPAAPRRRGSPERARPPPPPPPPAP 105
Query: 486 ATPTSPATVDAAVPG 500
P A A PG
Sbjct: 106 PRPPPAAPSPPAAPG 120
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 60.5 bits (145), Expect = 5e-09
Identities = 82/324 (25%), Positives = 121/324 (37%), Gaps = 36/324 (11%)
Query: 111 ERKPGPLEARE-RRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEA 169
E +P PL++ E RR R+ K + + E R E+RL Q L R E
Sbjct: 209 EEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRL-----QALERRLWEE 263
Query: 170 RDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESA 229
++ E G+ EA + +P E +RSL + R +E RL E
Sbjct: 264 NRRQELLEEEGEGQEPPLEAER---APREEQQRSLEAPGWEDAERREREERERLEAEE-- 318
Query: 230 YQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAP 289
E + + ++ + + L + E R R EE +EE R+EE G
Sbjct: 319 -------ERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEE 371
Query: 290 KETAELSETLTREAQGNSSAGVEAAEQRPV-EDGERGMKPTEGWKWTLNSGKAREWTPRD 348
E E EA + G AE+ + E+ E G E W+ L+ D
Sbjct: 372 LEQQEAEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSE------LLND 425
Query: 349 IEAQTQKPE--PPESAEKLLESPGV---EAGEGEAEKEEAGAQGRPLRALQNCCSVPSPL 403
E + + E PE + E PG+ + E E +E+ G G A P P
Sbjct: 426 FEERLEDQERLKPEGQREHSEEPGICEEQNPEAERRREQQGRSGDFQGA-----DRPGPE 480
Query: 404 PPEDAG-TGGLRQQEEEAVELQPP 426
+ G T L +QE QPP
Sbjct: 481 EKREEGDTEPLLKQEGPVEAAQPP 504
Score = 45.1 bits (105), Expect = 2e-04
Identities = 69/301 (22%), Positives = 124/301 (41%), Gaps = 20/301 (6%)
Query: 6 DWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTV 65
D+ +L A+ ++++A + + E +RL + +R E RR +L GE
Sbjct: 226 DYWRELEAKCKRQKAEAAEKRRLEEQRLQALE--RRLWEENRRQELLEEEGEGQEPPLEA 283
Query: 66 EAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPS 125
E P + + + LEA G + ER++++++++ E R +A ERR
Sbjct: 284 ERAPREEQQRS--LEAPG------WEDAERREREERERLEAEEERRRLQAQAQAEERRRL 335
Query: 126 PGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGD-RSS 184
+ R + + +E E R + R+ G +EL + E + ++ E G+ R
Sbjct: 336 EEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQEAEVQGPPEALEETGEGRRG 395
Query: 185 RLSEAWKWRLSPGETPERSLR--LAESREQSPRRKEVESRLSP-GESAY-QKLGLTEAHK 240
E G+ R L+E R E + RL P G+ + ++ G+ E
Sbjct: 396 AEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLKPEGQREHSEEPGICEEQN 455
Query: 241 WRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPV----PGVAPKETAELS 296
+ R Q+ + + R E+R++ E K+E PV P V KE A L
Sbjct: 456 PEAERRREQQGRSGDFQGAD-RPGPEEKREEGDTEPLLKQEGPVEAAQPPVERKEAAALE 514
Query: 297 E 297
+
Sbjct: 515 Q 515
Score = 34.3 bits (77), Expect = 0.35
Identities = 44/172 (25%), Positives = 61/172 (35%), Gaps = 26/172 (15%)
Query: 289 PKETAELSETLTREAQGNSSAGVEAAEQRPV---------EDGERGMKPTEGWKWTLNSG 339
P+E + T A+ +SS V A P E + K K L
Sbjct: 907 PQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAANKMPLAQKPALAPK 966
Query: 340 KAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSV 399
+ P ++ +P E + P E E E +E+ + RP
Sbjct: 967 PTSQTPPASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESSDR-RP---------- 1015
Query: 400 PSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSR 451
PSP PE+ G R +EEEA E + P SPP PA +P P R
Sbjct: 1016 PSPPGPEER-KGQKRDEEEEATERK-----PASPPLPATQQEKPSQTPEAGR 1061
Score = 32.0 bits (71), Expect = 1.7
Identities = 37/157 (23%), Positives = 55/157 (35%), Gaps = 23/157 (14%)
Query: 348 DIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPED 407
D +A+ +K + S ++ AG EKE G AL++ S LP E
Sbjct: 861 DQQAEQKKKKRHSSTGDSADAGPPAAGSARGEKEMEGV------ALKHGPS----LPQER 910
Query: 408 AGTGGLRQQEEEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRR 467
R+ E + P A PPP + P P D +++ P
Sbjct: 911 KQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKAANKM------------PLA 958
Query: 468 SGHTFTVNPRRSVPPATPATPTS-PATVDAAVPGAGK 503
P PPA+P + S P V+ AG+
Sbjct: 959 QKPALAPKPTSQTPPASPLSKLSRPYLVELLSRRAGR 995
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 57.8 bits (138), Expect = 3e-08
Identities = 92/428 (21%), Positives = 153/428 (35%), Gaps = 47/428 (10%)
Query: 100 QQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRE---SREERLSPRETRERRLGI 156
+ + RS + R PL +++R + +P+GR SR S +R R
Sbjct: 590 RSRSRSPDSSGSRSHSPLRSKQRDVAQARTH-ANPRGRPKMGSRSTSESRSRSRSRSRSA 648
Query: 157 GGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAW-----------KWRLSPGETPERSLR 205
SL P +RD S E D SS A K R S + ++ R
Sbjct: 649 SSNSRKSLSPGVSRDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARR 708
Query: 206 LAESREQSPRRKEVESRLSPGESAYQKLGLTEAHK---WRPDSRESQEQSLVQLEATEWR 262
L++ K V RL P + +K EA +P + E+Q L + E
Sbjct: 709 LSQPESAE---KHVTQRLQPERGSPKKCEAEEAEPPAATQPQTSETQTSHLPESERIHHT 765
Query: 263 LRSGEERQDYSEECGRKEEWPVPGVA------------------PKETAELSETLTREAQ 304
+ EE + E + + P P + K+ + L ++ R+
Sbjct: 766 VEEKEEVTMDTSENRPENDVPEPPMPIADQVSNDDRPEGSVEDEEKKESSLPKSFKRKIS 825
Query: 305 GNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAR-EWTPRDIEAQTQKPEPPESAE 363
S+ A E G+ G K G K T +++ +P E
Sbjct: 826 VVSATKGVPAGNSDTEGGQPGRKRRWGASTATTQKKPSISITTESLKSLIPDIKPLAGQE 885
Query: 364 KLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVEL 423
+++ ++ E E E G G + L+ C +V +P E G Q+EEE E
Sbjct: 886 AVVDLHADDSRISEDETERNGDDGTHDKGLKICRTVTQVVPAEGQENG---QREEEEEEK 942
Query: 424 QPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPA 483
+P P+ P A PP + + ++ G + ++SG + T++ P
Sbjct: 943 EPEAEPPVPPQVSVEVALPPPAEHEVKKVTLGDTLTRRSISQQKSGVSITIDD----PVR 998
Query: 484 TPATPTSP 491
T P+ P
Sbjct: 999 TAQVPSPP 1006
Score = 33.5 bits (75), Expect = 0.59
Identities = 60/264 (22%), Positives = 107/264 (40%), Gaps = 43/264 (16%)
Query: 28 AERERLSQMPAWKRGLLERRRAKLGLSP-GEPSPVLGTVEAGPPDPDESAVLLEAIGPVH 86
AE++ L + RGLL R ++ G P P+ PP P
Sbjct: 1087 AEQDELD----YHRGLLVDRPSETKTEEQGIPRPL-----HPPPPPPVQPPQHPRAEQRE 1137
Query: 87 QNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSP 146
Q R +R++ +++++ +R E +ER+ + RE S RD+ K R +E+ S
Sbjct: 1138 QERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSE 1197
Query: 147 RETRERRLGIGGAQELSLRPLEARDWRQSPGEVGD---RSSRLSEAWKW-RLSPGETPER 202
++ + AQE + P ++ D R ++ + W L+ + ++
Sbjct: 1198 KKEK--------AQE------------EPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQK 1237
Query: 203 SLRLAE-SREQSPRRK---EVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEA 258
AE ++E+ RRK E E + E+ ++ E K R SRE + E
Sbjct: 1238 EAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRER----ER 1293
Query: 259 TEWRLRSGEER-QDYSEECGRKEE 281
R R +R ++ E GR+ +
Sbjct: 1294 ERERDRGDRDRDRERDRERGRERD 1317
Score = 30.0 bits (66), Expect = 6.5
Identities = 29/140 (20%), Positives = 62/140 (44%), Gaps = 3/140 (2%)
Query: 14 RRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPD 73
RRR+E A + ++ ++E+ + P K LL+ K +P L + + +
Sbjct: 1183 RRRKERAKSKEKKSEKKEKAQEEPPAK--LLDDLFRKTKAAPCIYWLPLTDSQIVQKEAE 1240
Query: 74 ESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQS 133
+ E + Q+ ++++ +++R+ +L E++ R+R RD+
Sbjct: 1241 RAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRG 1300
Query: 134 PKGRESREERLSPRETRERR 153
+ R+ +R RE R+RR
Sbjct: 1301 DRDRDRERDRERGRE-RDRR 1319
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 57.8 bits (138), Expect = 3e-08
Identities = 97/422 (22%), Positives = 151/422 (35%), Gaps = 67/422 (15%)
Query: 8 KLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTV-- 65
K Q + Q+ A + E E +S+M K G ++ G+ +P+ +
Sbjct: 525 KQQTIGELTQDTALTENDDSDEYEEMSEM---KEGKACKQHVSQGIFMTQPATTIEAFSD 581
Query: 66 -EAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARE-RR 123
E P+ E A + G Q +E + ++ E+L++ E E +
Sbjct: 582 EEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGKA 641
Query: 124 PSPGEMRDQSPKGRESR--EERLS--------PRETRERRLGIG-------GAQELSLRP 166
S GE D P+GR EE S RE E+ G G G +EL+
Sbjct: 642 KSVGEAED-GPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELA--- 697
Query: 167 LEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPG 226
E +W++ GE ++ R G ER+ + E E+ E E
Sbjct: 698 -EKEEWKKRDGEEQEQKER---------EQGHQKERNQEMEEGGEEEHGEGEEEEGDREE 747
Query: 227 ESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPG 286
E + G E + +E+ + E + GEE D E G +EE G
Sbjct: 748 EEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGE--GEEEETEGRG 805
Query: 287 VAPKETAELS-----------ETLTREAQGNSSAGV----------EAAEQRPVEDGERG 325
+E E+ E E +G G E E + E+GE G
Sbjct: 806 EEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEG 865
Query: 326 MKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGA 385
EG + G+ E + E + ++ E E+ E G E GEGE E+EE
Sbjct: 866 EGEEEGEE---GEGEGEE---EEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 919
Query: 386 QG 387
+G
Sbjct: 920 KG 921
Score = 51.6 bits (122), Expect = 2e-06
Identities = 73/306 (23%), Positives = 108/306 (35%), Gaps = 19/306 (6%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPG---------EMRDQSPKGRESREE 142
++ER Q+ ++ E E + G E E + G E + +G +EE
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779
Query: 143 RLSPRETRERRLGIGGAQELSLRPLEAR-DWRQSPGEVGDRSSRLSEAWKWRLSPGETPE 201
R E E G +E E R + ++ GEV + E R E E
Sbjct: 780 RAGKEEKGEEEGDQGEGEE---EETEGRGEEKEEGGEV--EGGEVEEGKGEREEEEEEGE 834
Query: 202 RSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEAT-E 260
E E+ +E E E + G E + + E + + + E E
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894
Query: 261 WRLRSGE-ERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPV 319
GE E ++ E G +EE G E E E E +G G E+
Sbjct: 895 GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGE-GEGEEEEGEGEGEDGEGEGEEEEG 953
Query: 320 E-DGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEA 378
E +GE EG + G+ E + E + + E E E G E GEGE
Sbjct: 954 EWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEG 1013
Query: 379 EKEEAG 384
E+EE G
Sbjct: 1014 EEEEEG 1019
Score = 48.9 bits (115), Expect = 1e-05
Identities = 74/308 (24%), Positives = 111/308 (36%), Gaps = 33/308 (10%)
Query: 93 QERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRER 152
Q+ ++Q Q++R++E+ + G E E G+ ++ K E +EE ER
Sbjct: 712 QKEREQGHQKERNQEM---EEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGER 768
Query: 153 RLGIGGAQELSLRPLEARDWRQSPGEV-GDRSSRLSEAWKWR---------LSPGETPE- 201
+E R E R ++ GE GD+ E + R + GE E
Sbjct: 769 E------KEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEG 822
Query: 202 RSLRLAESREQSPRRKEVESRLSPGESAYQK-LGLTEAHKWRPDSRESQEQSLVQLEATE 260
+ R E E +E E GE ++ G E + E E+ + E E
Sbjct: 823 KGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEE 882
Query: 261 WRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVE 320
EE + EE + E G E E E + G E + E
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942
Query: 321 DGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEA-GEGEAE 379
DGE + EG EW + E + + E E + E G E GEGE E
Sbjct: 943 DGEGEGEEEEG-----------EWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGE 991
Query: 380 KEEAGAQG 387
+EE +G
Sbjct: 992 EEEGEEEG 999
Score = 48.5 bits (114), Expect = 2e-05
Identities = 80/376 (21%), Positives = 136/376 (36%), Gaps = 49/376 (13%)
Query: 17 QEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPDESA 76
+E V G K + E LS + K +S G+ V G E GP +
Sbjct: 610 EENVKVHGGRKEKTEILS----------DDLTDKAEVSEGKAKSV-GEAEDGPEGRGDGT 658
Query: 77 VLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKG 136
+ G H +ER++ ++ + R E +PG E + E + + +
Sbjct: 659 CEEGSSGAEHWQD---EEREKGEKDKGRGEM----ERPG--EGEKELAEKEEWKKRDGEE 709
Query: 137 RESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSP 196
+E +E ++ R + + GG +E + E GDR + + +
Sbjct: 710 QEQKEREQGHQKERNQEMEEGGEEEHG----------EGEEEEGDREEEEEKEGEGK-EE 758
Query: 197 GETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQL 256
GE E + RE+ ++ E R E ++ E + + R +++ ++
Sbjct: 759 GEGEE----VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEV 814
Query: 257 EATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQ 316
E E GE ++ E G +EE G +E E E +G E E
Sbjct: 815 EGGEVEEGKGEREEEEEEGEGEEEE----GEGEEEEGE-----GEEEEGEGKGEEEGEEG 865
Query: 317 RPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGV----- 371
E+GE G E + + E + E + + E E + E G
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEG 925
Query: 372 EAGEGEAEKEEAGAQG 387
E GEGE E+EE +G
Sbjct: 926 EEGEGEGEEEEGEGEG 941
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 57.0 bits (136), Expect = 5e-08
Identities = 82/364 (22%), Positives = 133/364 (36%), Gaps = 41/364 (11%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+ + QQQQQQQ+ ++ +++P P ++E + E ++ K E E + +
Sbjct: 489 RRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEK-EKEKEAEKEEEKPEVENDKEDLLK 547
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGE--TPERSLRLAES 209
+ ++ + A R++ G R R++ + + E TP++S LA
Sbjct: 548 EKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASM 607
Query: 210 REQSPRRKEVESRLSPGESAYQKLGLTE-AHKWRPDSRESQEQSLVQLEATEWRLRSGEE 268
SR + E K GL E W +R +++ Q + + + +
Sbjct: 608 ELNE------SSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQN 661
Query: 269 RQDY---------SEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPV 319
+ E R+++ P A +E A E + ++GV E+ V
Sbjct: 662 LDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEME---ASGVSGNEEEMV 718
Query: 320 EDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGE-GEA 378
E+ E SG A D E+ P P A K + G+ G
Sbjct: 719 EEAEALHASGNEVPRGECSGPATVNNSSDTESI---PSPHTEAAK-------DTGQNGPK 768
Query: 379 EKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAP 438
GA G P P+P PPED EA PPPAP SP P P
Sbjct: 769 PPATLGADGPPP-------GPPTP-PPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPP 820
Query: 439 TAPQ 442
P+
Sbjct: 821 VVPK 824
Score = 43.1 bits (100), Expect = 7e-04
Identities = 60/244 (24%), Positives = 85/244 (34%), Gaps = 63/244 (25%)
Query: 283 PVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAR 342
P P AP + + +E + E A PVE+GE KP + +++GKA
Sbjct: 806 PTPPPAPPSPSAPPPVVPKEEKEE-----ETAAAPPVEEGEE-QKPPAAEELAVDTGKAE 859
Query: 343 EWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQN------- 395
E P E + E P + + G +AEK+E G+ GR A +
Sbjct: 860 E--PVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS-GRATTAKSSGAPQDSD 916
Query: 396 ---CCSVP--------------SPLPPEDAGTGG------------LRQQEEEAVELQP- 425
CS SP P TG L+Q ++ A + P
Sbjct: 917 SSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPI 976
Query: 426 ------PPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRS 479
PP +P PAP AP PP + P AP++ G + R
Sbjct: 977 VTKVHEPPREDAAPTKPAPPAPPPPQN-----------LQPESDAPQQPGSSPRGKSRSP 1025
Query: 480 VPPA 483
PPA
Sbjct: 1026 APPA 1029
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 56.6 bits (135), Expect = 7e-08
Identities = 80/364 (21%), Positives = 132/364 (36%), Gaps = 58/364 (15%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+ + QQQQQQQ+ ++ +++P P ++E + E ++ K E E + +
Sbjct: 489 RRGKSQQQQQQQQQQQQQQQQQPMPRSSQEEKDEK-EKEKEAEKEEEKPEVENDKEDLLK 547
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGE--TPERSLRLAES 209
+ ++ + A R++ G R R++ + + E TP++S LA
Sbjct: 548 EKTDDTSGEDNDEKEAVASKGRKTANSQGRRKGRITRSMANEANSEEAITPQQSAELASM 607
Query: 210 REQSPRRKEVESRLSPGESAYQKLGLTE-AHKWRPDSRESQEQSLVQLEATEWRLRSGEE 268
SR + E K GL E W +R +++ Q + + + +
Sbjct: 608 ELNE------SSRWTEEEMETAKKGLLEHGRNWSAIARMVGSKTVSQCKNFYFNYKKRQN 661
Query: 269 RQDY---------SEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPV 319
+ E R+++ P A +E A E + ++GV E+ V
Sbjct: 662 LDEILQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEME---ASGVSGNEEEMV 718
Query: 320 EDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGE-GEA 378
E+ E T+N+ E P P A K + G+ G
Sbjct: 719 EEAEA----------TVNNSSDTE----------SIPSPHTEAAK-------DTGQNGPK 751
Query: 379 EKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAP 438
GA G P P+P PPED EA PPPAP SP P P
Sbjct: 752 PPATLGADGPPP-------GPPTP-PPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPP 803
Query: 439 TAPQ 442
P+
Sbjct: 804 VVPK 807
Score = 42.7 bits (99), Expect = 0.001
Identities = 60/245 (24%), Positives = 85/245 (34%), Gaps = 64/245 (26%)
Query: 283 PVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAR 342
P P AP + + +E + E A PVE+GE KP + +++GKA
Sbjct: 789 PTPPPAPPSPSAPPPVVPKEEKEE-----ETAAAPPVEEGEE-QKPPAAEELAVDTGKAE 842
Query: 343 EWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQN------- 395
E P E + E P + + G +AEK+E G+ GR A +
Sbjct: 843 E--PVKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGS-GRATTAKSSGAPQDSD 899
Query: 396 ---CCSVP--------------SPLPPEDAGTGG------------LRQQEEEAVELQP- 425
CS SP P TG L+Q ++ A + P
Sbjct: 900 SSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPI 959
Query: 426 -------PPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRR 478
PP +P PAP AP PP + P AP++ G + R
Sbjct: 960 QVTKVHEPPREDAAPTKPAPPAPPPPQN-----------LQPESDAPQQPGSSPRGKSRS 1008
Query: 479 SVPPA 483
PPA
Sbjct: 1009 PAPPA 1013
>gi|116292174 fidgetin-like 2 [Homo sapiens]
Length = 653
Score = 56.6 bits (135), Expect = 7e-08
Identities = 62/193 (32%), Positives = 71/193 (36%), Gaps = 26/193 (13%)
Query: 356 PEPPESAEKLLES-PGVEAGEGEAEKEEAGAQ------GRPLRALQNCCSVPSPLPPEDA 408
PEPP L E PG ++G G G+ PL A N C PS P A
Sbjct: 102 PEPPYPLASLHEGLPGTKSGGGGGSGALGGSPVLAGNLPEPLYA-GNACGGPSAAPEYAA 160
Query: 409 GTGGLRQQE----EEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGA 464
G GG + L PPPPA L PPP P P PL + G A PG GA
Sbjct: 161 GYGGGYLAPGYCAQTGAALPPPPPAALLQPPPPP--GYGPSAPLYNYPAGGYAAQPGYGA 218
Query: 465 PRRSGHTFTVNPRRSVPPATPATPTSPATVDAAVPGAGKK-RYPTAEEILVLGGYLRLSR 523
+ P PPA TP PA P +PTA G L L R
Sbjct: 219 ---------LPPPPGPPPAPYLTPGLPAPTPLPAPAPPTAYGFPTAAPGAESG--LSLKR 267
Query: 524 SCLAKGSPERHHK 536
+G R+ K
Sbjct: 268 KAADEGPEGRYRK 280
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 56.2 bits (134), Expect = 8e-08
Identities = 73/285 (25%), Positives = 116/285 (40%), Gaps = 21/285 (7%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R E+++++QQ +R +E + LE ERR Q + +E R E+ R+ E
Sbjct: 466 RHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEE 525
Query: 152 RRLGIGGAQELSL-RPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESR 210
RL E L R E R + E R + + + E ++ L+ E R
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEER 585
Query: 211 EQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWR----LRSG 266
Q ++E E RL Q+L E R + E +EQ L + E E R L+S
Sbjct: 586 RQQRLKREQEERLE------QRLKREEVE--RLEQEERREQRLKREEPEEERRQQLLKSE 637
Query: 267 EERQDYSEECGRKEEWPVPGVAPKETAE--LSETLTREAQGNSSAGVEAAEQRPVEDGER 324
E+ + ++ R+++ +E E L + L RE + E AE+ + ER
Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHE-EERREQELAEEEQEQARER 696
Query: 325 GMKPTEGWKWTLNS-GKARE----WTPRDIEAQTQKPEPPESAEK 364
W+W L S AR+ PR E Q ++ E E +
Sbjct: 697 IKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRR 741
Score = 56.2 bits (134), Expect = 8e-08
Identities = 100/428 (23%), Positives = 158/428 (36%), Gaps = 72/428 (16%)
Query: 12 LARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPD 71
L +R + E +R ++ RE+L + KR ERR +L E
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE-------------- 573
Query: 72 PDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRD 131
LL+ Q R +++E++++ +Q+ + EE+ + E R +R P E R
Sbjct: 574 --RRDQLLKREEERRQQR-LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 132 QSPKGRESREE------RLSPRETRERRLGIGGAQELSLRPL------EARDWRQSPGEV 179
Q E +EE R +E RE+RL +E + L E R+ + E
Sbjct: 631 QQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQ 690
Query: 180 GDRSSRLSE---AWKWRLSPGETPERSLRLAESREQ--SPRRKEVESRLSPGESAYQKLG 234
R+ W+W+L +S + R+Q RR+E E + ES Q
Sbjct: 691 EQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQE 750
Query: 235 LTEAHK------------WRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEW 282
AH+ W+ + E E+ +L A LR ERQ +EE ++E+
Sbjct: 751 EERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP-PLREQRERQLRAEERQQREQR 809
Query: 283 PVPGVAPKET--------------AELSETLTR-----EAQGNSSAGVEAAEQRPVEDGE 323
+P KE E E L R + Q E E+R ++
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR 869
Query: 324 RGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEA 383
R K W+W L + R + A+ E ++LL+ E E EK
Sbjct: 870 RDQK----WRWQLEEERKRR--RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923
Query: 384 GAQGRPLR 391
Q R R
Sbjct: 924 QEQERQYR 931
Score = 53.9 bits (128), Expect = 4e-07
Identities = 73/277 (26%), Positives = 120/277 (43%), Gaps = 32/277 (11%)
Query: 12 LARRRQEEASVRGREKAERE-RLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPP 70
L R+ +EE + RE+ +R + + W++ R+ + L EP +
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR-----QRELQ 272
Query: 71 DPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMR 130
+ +E LE + +R+ERQ+++QQQQR R+ E RE++ E +
Sbjct: 273 EEEEQLRKLE-------RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQ 325
Query: 131 DQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGD--RSSRLSE 188
++ + E RE++L RE ERR Q+L E R +Q E + R +L
Sbjct: 326 ERREQQEERREQQLR-REQEERR-----EQQLRREQEEERREQQLRREQEEERREQQLRR 379
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRES 248
+ R E+ LR REQ RR E +L + ++ L + R + E
Sbjct: 380 EQQLRREQQLRREQQLR----REQQLRR---EQQLRREQQLRREQQLRREQQLRREQEEE 432
Query: 249 QEQSLVQLEATEWRL-RSGEERQDY---SEECGRKEE 281
+ + + E E RL R EER+D+ EE R E+
Sbjct: 433 RHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
Score = 52.8 bits (125), Expect = 9e-07
Identities = 91/356 (25%), Positives = 141/356 (39%), Gaps = 47/356 (13%)
Query: 87 QNRFIRQERQQQQQQQQRSEELLAERKPGPLEAR----ERRPSPGEMRDQSPKGRESREE 142
Q R ++ER++Q+ ++Q EE L +R + R ERR + ++ +E RE+
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQ 565
Query: 143 RLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPER 202
RL RE ERR +L R E R R + RL RL E E+
Sbjct: 566 RLK-REQEERR------DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQ 618
Query: 203 SLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSL---VQLEAT 259
L+ E E+ RR+++ E Q+L R + +E +EQ L + E
Sbjct: 619 RLKREEPEEE--RRQQLLKSEEQEERRQQQL--------RREQQERREQRLKREEEEERL 668
Query: 260 EWRLRSGEERQDYSEECGRKEEWP----VPGVAPKETAEL-SETLTREAQGNSSAGVEAA 314
E RL+ E + +E +E+ + PK +L SE R+++ S +
Sbjct: 669 EQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG 728
Query: 315 EQRPVEDGERGMKPTEGWKW----TLNSGKAREWTPRDIEAQTQKPEPPESAEKLLES-- 368
++R E E+ + +W + + E RD Q Q E E + L +
Sbjct: 729 QRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARP 788
Query: 369 PGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVELQ 424
P E E + EE Q R R LP E+ RQ+ E ELQ
Sbjct: 789 PLREQRERQLRAEE--RQQREQRF----------LPEEEEKEQRRRQRREREKELQ 832
Score = 50.4 bits (119), Expect = 5e-06
Identities = 68/273 (24%), Positives = 112/273 (41%), Gaps = 18/273 (6%)
Query: 15 RRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPDE 74
RR++E + +E+A S++P W+ L A+ P G + + +E
Sbjct: 680 RREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEG--QRRRQEQEE 737
Query: 75 SAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARER---RPSPGEMRD 131
E+ + R RQQQ+++Q+R + + R+R RP E R+
Sbjct: 738 KRRRRES--ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Query: 132 QSPKG--RESREERLSPRET-RERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSE 188
+ + R+ RE+R P E +E+R +E L+ LE + Q R R +
Sbjct: 796 RQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQ-------RRERAQQ 848
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRES 248
+ E ER + R+Q R + E R + Y K L E + +
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 249 QEQSLVQLEATEWRLRSGEERQDYSEECGRKEE 281
+E+ L Q E E R R +ERQ EE ++EE
Sbjct: 909 EEEEL-QREEREKRRRQEQERQYREEEQLQQEE 940
Score = 50.1 bits (118), Expect = 6e-06
Identities = 71/292 (24%), Positives = 111/292 (38%), Gaps = 38/292 (13%)
Query: 96 QQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRERRLG 155
++++ + E LL +R+ E +RR P + + + G+ R++R + +ER L
Sbjct: 97 EEKRARCDGKESLLQDRRQ---EEDQRRFEPRDRQLEEEPGQRRRQKR----QEQERELA 149
Query: 156 IGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPR 215
G Q LE RD R R E W+ R E ER R E + QS +
Sbjct: 150 EGEEQSEKQERLEQRD----------RQRRDEELWRQRQEWQEREER--RAEEEQLQSCK 197
Query: 216 RKEVESRLSPGESAYQKLGLTEAHK-----WRPDSRESQEQSLVQLEATEWRLRSGEERQ 270
E E P E ++ L E + + RE Q++ + E EWR R
Sbjct: 198 GHETEE--FPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKR------ 249
Query: 271 DYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTE 330
E RKEE + P+ EL E E Q E +R E+ ++ E
Sbjct: 250 ---ETVLRKEEEKLQEEEPQRQRELQE---EEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Query: 331 GWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEE 382
+ RE E Q ++ + E E+ L E E + +E+
Sbjct: 304 QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQ 355
Score = 49.3 bits (116), Expect = 1e-05
Identities = 99/428 (23%), Positives = 159/428 (37%), Gaps = 59/428 (13%)
Query: 10 QLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERR-------------------RAK 50
QL RQE R E+ +++RL + +R E R R +
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336
Query: 51 LGLSPGEPSPVLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLA 110
L + + + L + + +R+E+Q +++QQ R E+ L
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396
Query: 111 E----RKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRP 166
R+ L ++ ++R + RE EER + +ERR Q L
Sbjct: 397 REQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERR-----EQRLKREQ 451
Query: 167 LEARDWRQSPGEV-------------GDRSSRLSEAW-----KWRLSPGETPERSLR--L 206
E RDW + E D+ E W + R E E+ LR
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRL-RS 265
E REQ +R+E E RL + Q+L E + R + +E+ ++ E E RL R
Sbjct: 512 EERREQRLKRQEEEERLQQRLRSEQQL-RREQEERREQLLKREEEKRLEQERREQRLKRE 570
Query: 266 GEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQR-----PVE 320
EER+D + R+EE + ++ L + L RE + E EQR P E
Sbjct: 571 QEERRD--QLLKREEERRQQRLKREQEERLEQRLKRE-EVERLEQEERREQRLKREEPEE 627
Query: 321 DGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEK 380
+ + + +E + RE R E + ++ E E E+ L+ E +
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERR-EQRLKREEEEERLEQRLKREHEEERREQELA 686
Query: 381 EEAGAQGR 388
EE Q R
Sbjct: 687 EEEQEQAR 694
Score = 48.1 bits (113), Expect = 2e-05
Identities = 71/312 (22%), Positives = 122/312 (39%), Gaps = 34/312 (10%)
Query: 74 ESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARE-RRPSPGEMRDQ 132
E +L E + + ++ RQ+Q++Q + E+L E + E RE RR E + +
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961
Query: 133 SPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEV--GDRSSRLSEAW 190
K + +EE+L E +RR QE + E + +Q ++ +R R + W
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRR-----RQEREKKYREEEELQQEEEQLLREEREKRRRQEW 1016
Query: 191 KWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQE 250
+ + + L + EQ R + + RL E Y R + QE
Sbjct: 1017 ERQY------RKKDELQQEEEQLLREEREKRRLQERERQY-----------REEEELQQE 1059
Query: 251 QSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAG 310
+ + E E R R ERQ EE ++EE + +E E RE Q
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQL----LREEPEKRRRQERERQCREEEE 1115
Query: 311 VEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPG 370
++ E++ + + + E L E + E Q + EP + + LE
Sbjct: 1116 LQQEEEQLLREEREKRRRQE-----LERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 371 VEAGEGEAEKEE 382
E E + E+E+
Sbjct: 1171 REEEELQQEEEQ 1182
Score = 47.0 bits (110), Expect = 5e-05
Identities = 46/195 (23%), Positives = 85/195 (43%), Gaps = 18/195 (9%)
Query: 87 QNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSP 146
+ + +++ +QQ +Q+R + L E + + R+R+ E+R Q P+ + EE+
Sbjct: 1466 EEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLH 1525
Query: 147 RETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETP------ 200
R+ R+R+ +E LR E R+ DR + E + R E
Sbjct: 1526 RQQRQRKF---LQEEQQLRRQERGQQRRQ-----DRDRKFREEEQLRQEREEQQLSRQER 1577
Query: 201 ERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATE 260
+R RL EQ RR+E E + E ++ + + D + +++ L+Q E E
Sbjct: 1578 DRKFRL---EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ-EREE 1633
Query: 261 WRLRSGEERQDYSEE 275
+L E + + EE
Sbjct: 1634 QQLHRQERDRKFLEE 1648
Score = 45.8 bits (107), Expect = 1e-04
Identities = 67/290 (23%), Positives = 110/290 (37%), Gaps = 52/290 (17%)
Query: 6 DWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTV 65
D K LL RRQEE R R+R + +R +R+ + L+ GE
Sbjct: 104 DGKESLLQDRRQEEDQ---RRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE---- 156
Query: 66 EAGPPDPDESAVLLEAIGPVHQNRFIRQERQ--------QQQQQQQRSEELLAERKPGPL 117
Q R +++RQ Q+Q+ Q+R E E +
Sbjct: 157 --------------------KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSC 196
Query: 118 EARERRPSPGE----MRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWR 173
+ E P E R+ R+ REE+ R R+ R+ + E ++WR
Sbjct: 197 KGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV---------FQEEEEKEWR 247
Query: 174 QSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLS--PGESAYQ 231
+ + +L E R + E LR E +E R+E E + E +
Sbjct: 248 KRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 232 KLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEE 281
+ E + + + RE QE+ Q E E +LR E+++ E+ R+E+
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLR--REQEERREQQLRREQ 355
Score = 45.1 bits (105), Expect = 2e-04
Identities = 95/448 (21%), Positives = 170/448 (37%), Gaps = 55/448 (12%)
Query: 14 RRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLS-PGEPSPVLGT--VEAGPP 70
RRRQE+ R R ++E + + A ++ E +R E G + A PP
Sbjct: 730 RRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPP 789
Query: 71 DPDESAVLLEAIG-PVHQNRFIRQERQQQQQQQQRSE--------------------ELL 109
++ L A + RF+ +E +++Q+++QR E + L
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQL 849
Query: 110 AERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRET------------RERRLGIG 157
E + G E +ERR S + RDQ + + EER R T +E++L
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRW-QLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 158 GAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRK 217
+EL E R ++ + + E + E R R + R+ ++
Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 218 EVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECG 277
+ E L GE ++ K+R + QE+ + E E R R ERQ ++
Sbjct: 969 KEEQLL--GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDEL 1026
Query: 278 RKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLN 337
++EE + +E E RE Q ++ E++ + + + E L
Sbjct: 1027 QQEEEQL----LREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE-----LE 1077
Query: 338 SGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCC 397
+E + E Q + EP + + E E E + E+E+ + R R Q
Sbjct: 1078 RQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE-- 1135
Query: 398 SVPSPLPPEDAGTGGLRQQEEEAVELQP 425
L + ++Q+EE+ + +P
Sbjct: 1136 -----LERQYREEEEVQQEEEQLLREEP 1158
Score = 44.7 bits (104), Expect = 3e-04
Identities = 49/192 (25%), Positives = 87/192 (45%), Gaps = 24/192 (12%)
Query: 87 QNRFIRQERQQQQQQQQ------RSEELLAERKPGPL--EARERRPSPGEMRDQSPKGRE 138
+ + +R+ER++++++Q+ E+LL ER+ PL + R+R+ E+R Q +
Sbjct: 1317 EKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKF 1376
Query: 139 SREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGE 198
EE+ R+ RER+ + Q+L + E + + + + +LS
Sbjct: 1377 LEEEQRLRRQERERKF-LKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR---------- 1425
Query: 199 TPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEA 258
ER + E EQ RR+E E + E Q+L K+R + + QE+ QL
Sbjct: 1426 -QERDRKFRE-EEQQVRRQERERKFLEEE---QQLRQERHRKFREEEQLLQEREEQQLHR 1480
Query: 259 TEWRLRSGEERQ 270
E + EE Q
Sbjct: 1481 QERDRKFLEEEQ 1492
Score = 43.9 bits (102), Expect = 4e-04
Identities = 70/291 (24%), Positives = 114/291 (39%), Gaps = 38/291 (13%)
Query: 14 RRRQE-EASVRGREKAERER---LSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGP 69
RRRQE E R E+ ++E L + P +RRR +L E +
Sbjct: 1131 RRRQELERQYREEEEVQQEEEQLLREEPE------KRRRQELERQYREEEEL-------- 1176
Query: 70 PDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEM 129
+E +L E Q R + +++ Q+Q+R + E + L+ + +
Sbjct: 1177 -QQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235
Query: 130 RDQSP--KGRESREER------LSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGD 181
RD KGRE+ + R L R++++ + G Q+ R E R W+Q +
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
Query: 182 RSSRLSEAWKW-RLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQK-----LGL 235
E K + ++ E L E RE+ RR+E + + E Q+ L
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR 1355
Query: 236 TEA-HKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEE----CGRKEE 281
E K+R + QEQ LE + R ER+ EE C +E+
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQ 1406
Score = 43.5 bits (101), Expect = 6e-04
Identities = 69/284 (24%), Positives = 114/284 (40%), Gaps = 45/284 (15%)
Query: 14 RRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPD 73
RR++ E R E+ ++E + + +RRR +L E V +
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLREERE---KRRRQELERQYREEEEV---------QQE 1149
Query: 74 ESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERR-PSPGEMRDQ 132
E +L E + RQ R++++ QQ+ E+LL E + + RER+ E++ Q
Sbjct: 1150 EEQLLREEPEKRRRQELERQYREEEELQQEE-EQLLREEQEKRRQERERQYREEEELQRQ 1208
Query: 133 SPKGRESREERLS----------PRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDR 182
K R E++ S R+ ++ G + R LE ++ DR
Sbjct: 1209 KRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLE-------DSQLRDR 1261
Query: 183 SSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWR 242
S+ + GE ER REQ RR + R P E ++ EA R
Sbjct: 1262 QSQQD----LQHLLGEQQER------DREQERRRWQQRDRHFPEEEQLEREEQKEAK--R 1309
Query: 243 PDSRESQEQSLVQLEATEWRLRSGEERQDYSEE--CGRKEEWPV 284
D + +E+ L++ E E R R +R+ EE +EE P+
Sbjct: 1310 RDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353
Score = 43.5 bits (101), Expect = 6e-04
Identities = 52/194 (26%), Positives = 86/194 (44%), Gaps = 21/194 (10%)
Query: 87 QNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERR--PSPGEMRDQSPKGRESREERL 144
+ + +++ +QQ ++Q+R + E + + RER+ ++R Q + R+ REE
Sbjct: 1672 EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE-RKFREEEQ 1730
Query: 145 SPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSL 204
+ET + +L QE + LE R P + R K+R E L
Sbjct: 1731 LRQETEQEQL---RRQERYRKILEEEQLR--PEREEQQLRRQERDRKFR------EEEQL 1779
Query: 205 RLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQ---EQSLVQLEATEW 261
R E EQ R +E + + E Q+ E + RP R+ + E+ +QLE E
Sbjct: 1780 R-QEREEQQLRSQESDRKFREEEQLRQE---REEQQLRPQQRDGKYRWEEEQLQLEEQEQ 1835
Query: 262 RLRSGEERQDYSEE 275
RLR +RQ +EE
Sbjct: 1836 RLRQERDRQYRAEE 1849
Score = 43.5 bits (101), Expect = 6e-04
Identities = 48/192 (25%), Positives = 85/192 (44%), Gaps = 8/192 (4%)
Query: 92 RQERQQQQQQQQRSEELL--AERKPGPLEARERRPSPGEMR-DQSPKGRESREERLSPRE 148
R+ R+++Q +Q+ +E L ER LE + RP E + + + R+ REE +E
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE 1782
Query: 149 TRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAE 208
E++L +QE + E RQ E R + ++W + E+ RL +
Sbjct: 1783 REEQQL---RSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQ 1839
Query: 209 SREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPD-SRESQEQSLVQLEATEWRLRS-G 266
R++ R +E + Q+L E K R + R+ +E+ + + + E R R G
Sbjct: 1840 ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVG 1899
Query: 267 EERQDYSEECGR 278
E + + GR
Sbjct: 1900 EIKSQEGKGHGR 1911
Score = 41.6 bits (96), Expect = 0.002
Identities = 52/210 (24%), Positives = 90/210 (42%), Gaps = 15/210 (7%)
Query: 73 DESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
+E +L E + + RQ R++ + QQ+ + L ER+ L+ RER + R++
Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER-----QYREE 1053
Query: 133 SPKGRESREERLSPRETRERR-LGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWK 191
+E + RETR R+ L +E L+ E + R+ P ++ R +
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEP----EKRRRQERERQ 1109
Query: 192 WRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQ 251
R E L E RE+ RR+E+E + E Q+ E R + + + Q
Sbjct: 1110 CREEEELQQEEEQLLREEREKR-RRQELERQYREEEEVQQE----EEQLLREEPEKRRRQ 1164
Query: 252 SLVQLEATEWRLRSGEERQDYSEECGRKEE 281
L + E L+ EE+ E+ R++E
Sbjct: 1165 ELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Score = 37.7 bits (86), Expect = 0.031
Identities = 51/218 (23%), Positives = 84/218 (38%), Gaps = 29/218 (13%)
Query: 16 RQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSP-----------VLGT 64
R+EE +R R++ ER+ L + +R LER+ + E +L
Sbjct: 1694 REEEQQLR-RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEE 1752
Query: 65 VEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRP 124
+ P ++ E + +RQER++QQ + Q S+ E + E E+
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ-- 1810
Query: 125 SPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSS 184
++R Q G+ EE E +E+R LR R +R S
Sbjct: 1811 ---QLRPQQRDGKYRWEEEQLQLEEQEQR----------LRQERDRQYRAEEQFATQEKS 1857
Query: 185 RLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESR 222
R E W+ E R R + RE+ RR++ E +
Sbjct: 1858 RREEQELWQ--EEEQKRRQERERKLREEHIRRQQKEEQ 1893
Score = 35.4 bits (80), Expect = 0.16
Identities = 44/184 (23%), Positives = 71/184 (38%), Gaps = 26/184 (14%)
Query: 93 QERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRER 152
+E +QQ +Q+R + E + + RER+ E + + + R+ REE +E E+
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476
Query: 153 RLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQ 212
+L QE + LE ++ R E +R R E R Q
Sbjct: 1477 QL---HRQERDRKFLEE-----------EQQLRRQER-----------DRKFREQELRSQ 1511
Query: 213 SPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSR-ESQEQSLVQLEATEWRLRSGEERQD 271
P RK +E Q+ L E + R R + + Q + E +LR E Q
Sbjct: 1512 EPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQ 1571
Query: 272 YSEE 275
S +
Sbjct: 1572 LSRQ 1575
Score = 32.0 bits (71), Expect = 1.7
Identities = 56/213 (26%), Positives = 90/213 (42%), Gaps = 28/213 (13%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRET-- 149
R Q++++ QQR E + E +E + + +++ RE REE+ +ET
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336
Query: 150 --RERRLGIGGAQELSLRPLEA-RDWRQSPGEVGDRSSR-LSEAWKWRLSPGE----TPE 201
RE + +E LR E R +R+ ++ + L E + R E E
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
Query: 202 RSLRLAESREQSPRR------KEVESRLSPGESAYQKLGLTEAHKWRPDSRE----SQEQ 251
+ LR E REQ R+ +E E +LS E + E + R RE +EQ
Sbjct: 1397 QQLRCQE-REQQLRQDRDRKFREEEQQLSRQER--DRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 252 SLVQLEATEWR-----LRSGEERQDYSEECGRK 279
L Q ++R L+ EE+Q + +E RK
Sbjct: 1454 QLRQERHRKFREEEQLLQEREEQQLHRQERDRK 1486
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 93/417 (22%), Positives = 160/417 (38%), Gaps = 53/417 (12%)
Query: 86 HQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLS 145
H +QE Q + +QQ + L E++ G LE E++ E+ +Q +E +L
Sbjct: 162 HLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQEGQLELPEQ-------QEGQLE 214
Query: 146 PRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLR 205
E +E +L + QE L + ++ + E + LSE + +L E E L
Sbjct: 215 LPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQEGQLKHLEHQEGQLE 274
Query: 206 LAESR--------EQSPRRKEVESRLSPGESAYQKLGL---TEAHKWRPDSRESQEQSLV 254
+ E + +Q + K ++ + E Q++G E + +P E QE L
Sbjct: 275 VPEEQMGQLKYLEQQEGQLKHLDQQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLE 334
Query: 255 QLEATEWRLRSGEERQDYSEECGRKE------------------EWPVPGVAPKETAELS 296
QLE E +L+ E+++ E +E + P +E +L
Sbjct: 335 QLEEQEGQLKHLEQQEGQLEHLEHQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLK 394
Query: 297 ETLTREAQGN---SSAGVEAAEQRPVEDGER---GMKPTEGWKWTLNSGKAREWTPRDIE 350
+ +E Q G ++R VE E+ +K E + L + ++ E
Sbjct: 395 HLVQQEGQLKHLVQQEGQLEQQERQVEHLEQQVGQLKHLEEQEGQLKHLEQQQGQLEVPE 454
Query: 351 AQTQKPEPPESAEKLLESPGVEAGE-GEAEKEEAGAQ------GRPLRALQNCCSVPSPL 403
Q +P+ E EK LE P + G+ EK+EA + G+P Q + P
Sbjct: 455 QQVGQPKNLEQEEKQLELPEQQEGQVKHLEKQEAQLELPEQQVGQPKHLEQQEKHLEHP- 513
Query: 404 PPEDAGTGGLRQQEEEAVELQPPP---PAPLSPPPPAPTAPQPPGDPLMSRLFYGVK 457
+D L QQE + +L+ P+ P P P P + V+
Sbjct: 514 EQQDGQLKHLEQQEGQLKDLEQQKGQLEQPVFAPAPGQVQDIQPALPTKGEVLLPVE 570
Score = 45.1 bits (105), Expect = 2e-04
Identities = 76/349 (21%), Positives = 136/349 (38%), Gaps = 43/349 (12%)
Query: 93 QERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRE-----------SRE 141
QE++ QQQ ++ EE P +E+ ++ Q + ++ R+
Sbjct: 83 QEQELQQQHWEQHEEYQKAENPEQQLKQEKTQRDQQLNKQLEEEKKLLDQQLDQELVKRD 142
Query: 142 ERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPE 201
E+L + +E+ L + QE L+ LE ++ + E + L E + +L E E
Sbjct: 143 EQLGMK--KEQLLELPEQQEGHLKHLEQQEGQLKHPEQQEGQLELPEQQEGQLELPEQQE 200
Query: 202 RSLRLAESRE-QSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATE 260
L L E +E Q ++ E +L E +L L + + + + E QE L E E
Sbjct: 201 GQLELPEQQEGQLELPEQQEGQLELPEQQEGQLELPQQQEGQLELSEQQEGQLELSEQQE 260
Query: 261 WRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVE 320
+L+ E ++ E P+E ++ + E Q ++ E++P
Sbjct: 261 GQLKHLEHQEGQLE-------------VPEE--QMGQLKYLEQQEGQLKHLDQQEKQP-- 303
Query: 321 DGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEK 380
+ E L + +E P+ +E Q + E E E L+ + G+ E +
Sbjct: 304 ------ELPEQQMGQLKHLEQQEGQPKHLEQQEGQLEQLEEQEGQLKHLEQQEGQLEHLE 357
Query: 381 EEAGAQGRP------LRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVEL 423
+ G G P L+ L+ P L E+ L QQE + L
Sbjct: 358 HQEGQLGLPEQQVLQLKQLEKQQGQPKHLEEEEGQLKHLVQQEGQLKHL 406
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 53.5 bits (127), Expect = 6e-07
Identities = 87/349 (24%), Positives = 125/349 (35%), Gaps = 50/349 (14%)
Query: 118 EARERRPSPG-EMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSP 176
+ + RPS + D+ + R+ +P E +R G + RPLE S
Sbjct: 977 DQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLEL----DSG 1032
Query: 177 GEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLT 236
GE ++ S E E+ E E E+ + E+ + L+
Sbjct: 1033 GEEDEKESLSEEQ--------ESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALS 1084
Query: 237 EAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPG------VAPK 290
EA + D +S E+ V + ++ S E + SE E P VA +
Sbjct: 1085 EASE--KDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVARE 1142
Query: 291 ETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIE 350
E E E + +SAG E EQ DGE G + G E ++
Sbjct: 1143 EEEEEEEEEMVAEESMASAGPEDFEQ----DGEEAAL-APGAPAVDSLGMEEE-----VD 1192
Query: 351 AQTQKPEPPESAEKLLESP---GVEAGEGEAEK-EEAGAQGRPLRALQNCCSVPSPLPP- 405
+T+ P E L E P GVE E EE G Q + SP PP
Sbjct: 1193 IETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLS-------QEGAMLLSPEPPA 1245
Query: 406 ---EDAGTGGLRQQEEEAVELQPPPPA----PLSPPPPAPTAPQPPGDP 447
E + E +E++P PP PL PP P P P+PP P
Sbjct: 1246 KEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPP 1294
Score = 36.2 bits (82), Expect = 0.091
Identities = 26/69 (37%), Positives = 27/69 (39%), Gaps = 12/69 (17%)
Query: 423 LQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPP 482
L PPP P PPPP P PQ PG P+ L P P H P PP
Sbjct: 681 LPPPPGFPPLPPPPPPPPPQ-PGFPMPPPL-------PPPPPPPPPAHPAVTVP----PP 728
Query: 483 ATPATPTSP 491
PA P P
Sbjct: 729 PLPAPPGVP 737
Score = 34.7 bits (78), Expect = 0.26
Identities = 18/44 (40%), Positives = 22/44 (50%), Gaps = 3/44 (6%)
Query: 425 PPPPAP---LSPPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAP 465
PPPP P + PP P P P PP P ++ + A PGV P
Sbjct: 696 PPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPP 739
Score = 33.5 bits (75), Expect = 0.59
Identities = 36/123 (29%), Positives = 43/123 (34%), Gaps = 32/123 (26%)
Query: 346 PRDIEAQTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPL-- 403
P + AQ + P P LL +P K GRP R+ + S+ PL
Sbjct: 1444 PAVLRAQARAPTP---LPPLLPAPLASCPPPMKRKP-----GRPRRSPPSMLSLDGPLVR 1495
Query: 404 PPEDAGTG-------GLRQ-------QEEEAVELQ--------PPPPAPLSPPPPAPTAP 441
PP A G G Q + V L PPPP P PPPP P P
Sbjct: 1496 PPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPP 1555
Query: 442 QPP 444
P
Sbjct: 1556 VEP 1558
Score = 33.1 bits (74), Expect = 0.77
Identities = 32/99 (32%), Positives = 37/99 (37%), Gaps = 10/99 (10%)
Query: 399 VPSPLPPEDAGTGGLRQQEEEAVELQPPPPAPL-SPPPPAPTAP-QPPGDPLMSRLFYGV 456
+P PLP A LR Q L P PAPL S PPP P +P P G
Sbjct: 1433 LPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGP 1492
Query: 457 KAGPGVGAPRRSGHTFTVNPRRSVPPATPATPTSPATVD 495
P GA + + P P TP P+T D
Sbjct: 1493 LVRPPAGA--------ALGRELLLLPGQPQTPVFPSTHD 1523
Score = 32.7 bits (73), Expect = 1.0
Identities = 20/50 (40%), Positives = 22/50 (44%), Gaps = 5/50 (10%)
Query: 399 VPSPLPPEDAGTGGLRQQEEEAVELQPPP-PAPLSPPPPAPTAPQPPGDP 447
+P PLPP AV + PPP PAP PPP P PP P
Sbjct: 705 MPPPLPPPPPPP----PPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPP 750
Score = 32.3 bits (72), Expect = 1.3
Identities = 60/242 (24%), Positives = 82/242 (33%), Gaps = 64/242 (26%)
Query: 409 GTGGLR------QQEEEAVELQPPPPAPLSPPP-----------PAPTAPQPPGDPLMSR 451
GTGG Q ++ A PPPA +P P P P PP +P +
Sbjct: 359 GTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATA 418
Query: 452 LFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPATPATPTSPATVDA-AVPGAGKKRYPTAE 510
F G RR+ + P + P TP P D ++ G+ + +
Sbjct: 419 AF----GARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSP 474
Query: 511 EILVLGGYLRLSRSCLAKGSPERHHKQL-------------KISF-----SETALETT-Y 551
E G L S PE+ H L K+ F S+T L+
Sbjct: 475 EPCDSPGTPTLESS---PAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGS 531
Query: 552 QYPSESSVLEELGP-----EPEVPSAPNPPAAQ--------------PDDEEDEEELLLL 592
S SS L L P +P P PP+++ PD +EDEE L L
Sbjct: 532 PISSSSSQLSPLAPFGTNSQPGF-RGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGL 590
Query: 593 QP 594
P
Sbjct: 591 GP 592
Score = 32.0 bits (71), Expect = 1.7
Identities = 53/208 (25%), Positives = 73/208 (35%), Gaps = 48/208 (23%)
Query: 402 PLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAGPG 461
P P E T ++ P PP PL PP P A + PG P PG
Sbjct: 409 PPPEEPTATAAFGARDSGEFRRAPAPP-PL--PPAEPLAKEKPGTP------------PG 453
Query: 462 VGAPRRSG------HTFTVNPRRSVPPATPATPTSPA-------TVDAAVPGAGKK---- 504
P + TF +P P TP +SPA ++D+ + K+
Sbjct: 454 PPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTK 513
Query: 505 ----RYPTAE-EILVLGGYLRLSRSCLAKGSPERHHKQLKISF--------SETALETTY 551
R P ++ E+ + G + S S L+ +P + Q S T LE
Sbjct: 514 LLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDIS 573
Query: 552 QYPSESSVLEE---LGPEPEVPSAPNPP 576
P S +E LG P P P PP
Sbjct: 574 PTPLPDSDEDEELDLGLGPRPPPEPGPP 601
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 52.4 bits (124), Expect = 1e-06
Identities = 81/371 (21%), Positives = 131/371 (35%), Gaps = 91/371 (24%)
Query: 243 PDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE 302
PD ++ E+ + LE L S E+ ++ + G +AE+ E L +
Sbjct: 1010 PDWIKNLEEEM-SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQH 1068
Query: 303 AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESA 362
Q +SS+G+ + + + T++ G R A ++ P PP
Sbjct: 1069 LQPSSSSGLGTSPSS-------SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-- 1119
Query: 363 EKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVE 422
AQ P+ A +PLP +D +
Sbjct: 1120 ----------------------AQSSPIDA-----QPATPLPQKDPA--------QPLEP 1144
Query: 423 LQPPPPAPLSPP--PPAPTAPQPPG---DPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPR 477
+PPPP P++PP P P P PP P +R +G G+GAP G V R
Sbjct: 1145 KRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFG-----GIGAPPSPG----VARR 1195
Query: 478 RSVPPATPATP------TSPATVDAAVPGAGKKRYPTAEEIL-----VLGGYLRLSRSCL 526
P +P T S + A + G G Y TA + V+ +R+
Sbjct: 1196 EMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASA 1255
Query: 527 AKGSPERHHKQLKIS----FSETALETTYQYPSESSV-----------------LEELGP 565
+ +PE K + S F L+ +P +SS+ + + GP
Sbjct: 1256 GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGP 1315
Query: 566 EPEVPSAPNPP 576
+P + + P PP
Sbjct: 1316 QPNLETPPQPP 1326
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 52.4 bits (124), Expect = 1e-06
Identities = 81/371 (21%), Positives = 131/371 (35%), Gaps = 91/371 (24%)
Query: 243 PDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE 302
PD ++ E+ + LE L S E+ ++ + G +AE+ E L +
Sbjct: 1010 PDWIKNLEEEM-SLEKISIALPSSTSSTLLGEDAEVAADFDMEGDVDDYSAEVEELLPQH 1068
Query: 303 AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESA 362
Q +SS+G+ + + + T++ G R A ++ P PP
Sbjct: 1069 LQPSSSSGLGTSPSS-------SPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPS-- 1119
Query: 363 EKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEAVE 422
AQ P+ A +PLP +D +
Sbjct: 1120 ----------------------AQSSPIDA-----QPATPLPQKDPA--------QPLEP 1144
Query: 423 LQPPPPAPLSPP--PPAPTAPQPPG---DPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPR 477
+PPPP P++PP P P P PP P +R +G G+GAP G V R
Sbjct: 1145 KRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFG-----GIGAPPSPG----VARR 1195
Query: 478 RSVPPATPATP------TSPATVDAAVPGAGKKRYPTAEEIL-----VLGGYLRLSRSCL 526
P +P T S + A + G G Y TA + V+ +R+
Sbjct: 1196 EMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASA 1255
Query: 527 AKGSPERHHKQLKIS----FSETALETTYQYPSESSV-----------------LEELGP 565
+ +PE K + S F L+ +P +SS+ + + GP
Sbjct: 1256 GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGP 1315
Query: 566 EPEVPSAPNPP 576
+P + + P PP
Sbjct: 1316 QPNLETPPQPP 1326
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 52.4 bits (124), Expect = 1e-06
Identities = 71/317 (22%), Positives = 129/317 (40%), Gaps = 39/317 (12%)
Query: 87 QNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGE--MRDQSPKGRES----- 139
+ + RQE++ ++Q+++ E+ R+ L +E + E M +Q K RE
Sbjct: 275 EEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMW 334
Query: 140 -REERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWK-WRLSPG 197
+EERL +E + R QE +R E R W Q + ++ R+ E K W
Sbjct: 335 RQEERLWEQEKQMRE------QEQKMRDQEERMWEQDE-RLREKEERMREQEKMW----- 382
Query: 198 ETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLE 257
E E+ RE+ + +E E + E QK E + W + +E Q+Q L + +
Sbjct: 383 EQEEKMQEEERIREREKKMREEEETMREQEEKMQK---QEENMWEQEEKEWQQQRLPEQK 439
Query: 258 ATEW---RLRSGEER--------QDYSEECGR-KEEWPVPGVAPKETAELSETLTREAQG 305
W +++ EE+ +D E G+ K+ W + +E + E
Sbjct: 440 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ---EEKMR 496
Query: 306 NSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKL 365
+ + E+R E ER + E + + E + + Q Q+ + + EK+
Sbjct: 497 DQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKM 556
Query: 366 LESPGVEAGEGEAEKEE 382
E + E + +EE
Sbjct: 557 REEERMREREKKMREEE 573
Score = 49.7 bits (117), Expect = 8e-06
Identities = 85/390 (21%), Positives = 153/390 (39%), Gaps = 48/390 (12%)
Query: 14 RRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPD 73
+ R++E +R +EK RE+ ++ ++ L E+++ + E + E + +
Sbjct: 270 KMREQEEKMRRQEKRLREQEKELREQEKELREQKKLR------EQEEQMQEQEEKMWEQE 323
Query: 74 ESAVLLEAIGPVHQNRFIRQERQQQQQQQQR--SEELLAERKPGPLEARERRPSPGEMRD 131
E E + R QE+Q ++Q+Q+ EE + E+ E ER +M +
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE 383
Query: 132 QSPKGRESREERLSPRETRER-RLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAW 190
Q K +E EER+ RE + R QE ++ E W Q E W
Sbjct: 384 QEEKMQE--EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKE-----------W 430
Query: 191 KWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAY---------QKLGLTEAHKW 241
+ + P E E+ + +EQ + E E ++ E + +K+ E W
Sbjct: 431 QQQRLP-EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 489
Query: 242 RPDSR-ESQEQSLVQLEATEW----RLRSGEERQDYSEECGRKE----EWPVPGVAPKET 292
+ + QEQ + E W RLR EER ++ ++E E K+T
Sbjct: 490 EQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Query: 293 AELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQ 352
+ E + E + E+ + + E M+ E + + + W + + Q
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE---KMREQEEKMWEQEE-KMQ 605
Query: 353 TQKPEPPESAEKLLESPGVEAGEGEAEKEE 382
Q+ + E EK+ E E + E+EE
Sbjct: 606 EQEEKMWEQEEKMWEQ---EEEDKMQEQEE 632
Score = 44.3 bits (103), Expect = 3e-04
Identities = 59/300 (19%), Positives = 110/300 (36%), Gaps = 44/300 (14%)
Query: 87 QNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSP 146
+ R Q++ QQ+++ R E+ E++ + E+ MR++ K RE E
Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579
Query: 147 RETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRL 206
E + QE +R E + W Q + + E W E+ ++
Sbjct: 580 EEKMQE-------QEEKMREQEEKMWEQ------EEKMQEQEEKMW--------EQEEKM 618
Query: 207 AESREQSPRRKEVESRLSPGESAY-QKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRS 265
E E+ +++ E E Q+ + E + + E + +++ E ++R
Sbjct: 619 WEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRE 678
Query: 266 GEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERG 325
EE+ EE R++E + G K + + +E + + E+R + E
Sbjct: 679 QEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKE-- 736
Query: 326 MKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPE------SAEKLLESPGVEAGEGEAE 379
K +E P E ++ PP S +E G EAGEG +
Sbjct: 737 --------------KMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQ 782
Score = 43.5 bits (101), Expect = 6e-04
Identities = 56/244 (22%), Positives = 103/244 (42%), Gaps = 38/244 (15%)
Query: 50 KLGLSPGEPSPVLGTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELL 109
KL L+ E S + V+ + + LL P Q +++E +Q+++ + E+ +
Sbjct: 195 KLRLAESEKSEIQLNVKELKRKLERAKFLL----PQVQTNTLQEEMWRQEEELREQEKKI 250
Query: 110 AERKPGPLEARER-RPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLE 168
+++ ER R G+MR+Q K R +E+RL +E R QE LR E
Sbjct: 251 RKQEEKMWRQEERLREQEGKMREQEEKMRR-QEKRLREQEKELRE------QEKELR--E 301
Query: 169 ARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESR-EQSPRRKEVESRLSPGE 227
+ R+ ++ ++ ++ W+ E E+ R E EQ + +E E
Sbjct: 302 QKKLREQEEQMQEQEEKM---WEQEEKMREQEEKMWRQEERLWEQEKQMREQE------- 351
Query: 228 SAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEW----------RLRSGEERQDYSEECG 277
QK+ E W D R +++ ++ + W R+R E++ EE
Sbjct: 352 ---QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETM 408
Query: 278 RKEE 281
R++E
Sbjct: 409 REQE 412
Score = 37.4 bits (85), Expect = 0.041
Identities = 70/308 (22%), Positives = 113/308 (36%), Gaps = 41/308 (13%)
Query: 106 EELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQ----- 160
EEL ER LE + E++ ++ + +E RL+ E E +L + +
Sbjct: 162 EELTKERDALSLELYRNTITNEELKKKNAELQEKL--RLAESEKSEIQLNVKELKRKLER 219
Query: 161 ------ELSLRPLEARDWRQSPG-EVGDRSSRLSEAWKWRLSPGETPERSLRLAESR--- 210
++ L+ WRQ ++ R E WR E LR E +
Sbjct: 220 AKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWR------QEERLREQEGKMRE 273
Query: 211 -EQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEER 269
E+ RR+E R E Q+ L E K R + QEQ E E ++R EE+
Sbjct: 274 QEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEE-KMREQEEK 332
Query: 270 QDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPT 329
EE ++E + K + E + + + EQ + + E M+
Sbjct: 333 MWRQEERLWEQEKQMREQEQK-MRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEE 391
Query: 330 EGWKWTLNSGKAREWTPRDIEAQTQKPEP---------------PESAEKLLESPGVEAG 374
E + + E T R+ E + QK E PE EKL E ++
Sbjct: 392 ERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 451
Query: 375 EGEAEKEE 382
E + ++E
Sbjct: 452 EEKIWEQE 459
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 52.4 bits (124), Expect = 1e-06
Identities = 106/447 (23%), Positives = 164/447 (36%), Gaps = 88/447 (19%)
Query: 70 PDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEM 129
P+P E + P ++ +++ + + + + RS+ R P R RR
Sbjct: 254 PEPKEPS-------PEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRS 306
Query: 130 RDQSPKGRESREERLSP-RETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSE 188
R SP+ R S R SP R T RR+ S P+ R R+S + SS S
Sbjct: 307 RSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRR--RRSSASLSGSSSSSSS 364
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKL-----GLTEAHKWR- 242
+ + R P + P+R+ SP RK RLSP S ++ T K R
Sbjct: 365 S-RSRSPPKKPPKRT--------SSPPRK--TRRLSPSASPPRRRHRPSPPATPPPKTRH 413
Query: 243 -PDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTR 301
P ++S ++ + R SG+ + E K E P P P++ ELSE +
Sbjct: 414 SPTPQQSNRTRKSRVSVSPGR-TSGKVTKHKGTE---KRESPSPAPKPRK-VELSE--SE 466
Query: 302 EAQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPES 361
E +G A ++ +QR + ++ SG + + D + + E
Sbjct: 467 EDKGGKMAAADSVQQRRQYRRQNQQSSSD-------SGSSS--SSEDERPKRSHVKNGEV 517
Query: 362 AEKLLESPGVEAGEGEAEKE-EAGAQGRPLRALQNCCSVPSPLPPEDAGTGGLRQQEEEA 420
+ SP A +++ E +GR R+ PSP P + +
Sbjct: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRS-------PSPPP----------TRRRRS 560
Query: 421 VELQPPPPAPLSP-PPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRS 479
PPP +P PPP P PP PRR + +PRR
Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPP--------------------PRRR----SPSPRRY 596
Query: 480 VPPATPA-TPTSPATVDAAVPGAGKKR 505
PP +P+ P A P KR
Sbjct: 597 SPPIQRRYSPSPPPKRRTASPPPPPKR 623
Score = 39.7 bits (91), Expect = 0.008
Identities = 116/593 (19%), Positives = 175/593 (29%), Gaps = 136/593 (22%)
Query: 27 KAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPDESAVLLEAIGPVH 86
+ + R+S P G + + + P+P VE + D+ + A V
Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAA-DSVQ 480
Query: 87 QNRFIRQERQQQQQQQQRSEELLAER------KPGPLEARERRPSPGEMRDQSPKGRESR 140
Q R R++ QQ S ER K G + R RR SP SP+ R
Sbjct: 481 QRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEV-GRRRRHSPSRSASPSPR---KR 536
Query: 141 EERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETP 200
++ SPR R R S P R R R R R +P P
Sbjct: 537 QKETSPRGRRRR----------SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586
Query: 201 ERSLRLAESREQSPRRKE--VESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEA 258
R R SPRR ++ R SP P R +
Sbjct: 587 RR-------RSPSPRRYSPPIQRRYSPSP---------------PPKRRTAS-------- 616
Query: 259 TEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRP 318
P PK A S R + ++
Sbjct: 617 --------------------------PPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTK 650
Query: 319 VEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPEPPESAEKLLESPGVEAGEGEA 378
K +G + ++ +AR P + + +P P+++ P V G +
Sbjct: 651 RRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSS---PPPVRRGASSS 707
Query: 379 --EKEEAGAQGRPLRALQNCCSVPSPLPPEDAGTGG----LRQQEEEAVELQPPPPAPLS 432
++ RP+R + P P + A + R +V P P A
Sbjct: 708 PQRRQSPSPSTRPIRRVSR---TPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764
Query: 433 PPPPAPTAPQPPGDPLMSRLFYGVKAGPGVGAPRRSGHTFTVNPRRSVPPATPATPTSPA 492
P PP+P Q P P V P + TP +P+ P
Sbjct: 765 PAPPSPVQSQSP----------STNWSPAV-------------PVKKAKSPTP-SPSPPR 800
Query: 493 TVDAAVPGAGKKRYPTAEEILVLGGYLRLSRSCLAKGSPERHHKQLKISFSETALETTYQ 552
D G KK+ + K + HK+ K + A
Sbjct: 801 NSDQEGGGKKKKKKKDKKH---------------KKDKKHKKHKKHKKEKAVAAAAAAAV 845
Query: 553 YPSESSVLEELGPEPEVPSAPNPPAAQPDDEEDEEELLLLQPELQGGLRTKAL 605
P+ + + E +AP P + ED + +L+ LR KAL
Sbjct: 846 TPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLD------DLEKHLREKAL 892
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 50.8 bits (120), Expect = 4e-06
Identities = 88/397 (22%), Positives = 154/397 (38%), Gaps = 43/397 (10%)
Query: 3 TIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVL 62
TI D +L+ + QE+ + EK+E + + KR L RAKL L P L
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQL--NVKELKRKL---ERAKLLL----PQQQL 263
Query: 63 GTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARER 122
EA + +V + V +N + QQQ+++ R EE + E + E E+
Sbjct: 264 -QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEK 322
Query: 123 -RPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGD 181
R ++R+Q K R E E R+ + +E +R LE W + ++ +
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEE-KIRE 381
Query: 182 RSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKW 241
++ E K R E E+ + REQ R+++ EA W
Sbjct: 382 LEEKMHEQEKIR----EQEEKRQEEEKIREQEKRQEQ------------------EAKMW 419
Query: 242 RPDSR-ESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLT 300
R + + QE+ + + E WR Q+ E +++E ++ E E
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 301 REAQGNSSAGVEAAEQR------PVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQ 354
++ + + + E++ + D E ++ E W K RE + E + +
Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWR-QEEKIREQEEKIREQEEK 538
Query: 355 KPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLR 391
E E ++ E G E E E+E+ Q +R
Sbjct: 539 IREQEEMMQEQEEKMG-EQEEKMQEQEKMRRQEEKIR 574
Score = 41.6 bits (96), Expect = 0.002
Identities = 50/211 (23%), Positives = 84/211 (39%), Gaps = 29/211 (13%)
Query: 85 VHQNRFIRQERQQQQQQQQ-RSEELLAE-----RKPGPLEARERRPSPGE--------MR 130
+H+ IR+E ++Q+Q++ R EE + E R+ + +E+ E M
Sbjct: 446 IHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMH 505
Query: 131 DQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAW 190
DQ K RE E+ E + QE +R E Q ++G++ ++ E
Sbjct: 506 DQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEE-KMGEQEEKMQEQE 564
Query: 191 KWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQE 250
K R + E+ ++ REQ + +E E ++ E K R QE
Sbjct: 565 KMRRQEEKIREQEEKI---REQKEKIREQEEKIWEQEE-----------KIREQEEMMQE 610
Query: 251 QSLVQLEATEWRLRSGEERQDYSEECGRKEE 281
Q E E E+ Q+ E+ R+EE
Sbjct: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
Score = 34.7 bits (78), Expect = 0.26
Identities = 32/142 (22%), Positives = 60/142 (42%), Gaps = 10/142 (7%)
Query: 87 QNRFIRQERQQQQQQQQR---SEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREE- 142
Q IR++ ++ ++Q+++ EE++ E++ E E+ +MR Q K RE E+
Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKI 580
Query: 143 RLSPRETRERRLGIG------GAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSP 196
R + RE+ I QE ++ E + W Q + K R
Sbjct: 581 REQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 197 GETPERSLRLAESREQSPRRKE 218
+ E+ +RL + E+ +E
Sbjct: 641 EKMWEQEVRLRQQEEKMQEHQE 662
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/385 (23%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 14 RRRQEEASVRGREKAE-RERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
RR +EE + +++AE RERL+++ A LE++R
Sbjct: 1342 RRMEEEERLAEQQRAEERERLAEVEA----ALEKQR------------------------ 1373
Query: 73 DESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
+ H + ER+ ++ QQ+ EE++ R+ ++A++++ S E Q
Sbjct: 1374 --------QLAEAHAQAKAQAEREAKELQQRMQEEVV-RREEAAVDAQQQKRSIQEELQQ 1424
Query: 133 SPKGRESR-EERLSPRETRER-RLGIGGAQELSLRPLEARDWRQ--SPGEVGDRSSRLSE 188
+ E+ + + E ER RL I + LEA + ++ + GE+ +R E
Sbjct: 1425 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEE 1484
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVE--SRL-SPGESAYQKLGLTEAHKWRPDS 245
A + E ER R + Q R+ EVE SR+ + E+A +K +A +
Sbjct: 1485 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1544
Query: 246 RESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE--- 302
E E+ L Q E R R + + ++ E ++TA+L +L E
Sbjct: 1545 AEEAERRLRQAEVE--RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1602
Query: 303 -----AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPE 357
+ A +A +R E+ ER ++ +W L + +A + E QK
Sbjct: 1603 VAQLREEAERRAQQQAEAERAREEAERELE-----RWQLKANEALRLRLQAEEVAQQKSL 1657
Query: 358 PPESAEKLLESPGVEA-GEGEAEKE 381
AEK E EA G+AE++
Sbjct: 1658 AQAEAEKQKEEAEREARRRGKAEEQ 1682
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/222 (22%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+E +++ Q+ +EE A ++ LE ER K + RL R +E
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERL-----------KAKVEEARRLRERAEQE 2031
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLS-----PGETPERSLRL 206
+ AQE + + L+A + + V + L + + S GE E + R
Sbjct: 2032 SARQLQLAQEAAQKRLQAEE-KAHAFAVQQKEQELQQTLQQEQSVLDQLRGEA-EAARRA 2089
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSG 266
AE E++ + E E+A + + EA + + S E Q Q+ Q +A +LR
Sbjct: 2090 AEEAEEARVQAE-------REAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKE 2141
Query: 267 EE----RQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQ 304
E R+ +E+ +++ K +TL ++AQ
Sbjct: 2142 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ 2183
Score = 35.4 bits (80), Expect = 0.16
Identities = 60/274 (21%), Positives = 100/274 (36%), Gaps = 24/274 (8%)
Query: 13 ARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
AR+RQ A R + ER+ + A + +R+A L + V
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2029
Query: 73 DESAVLLEAIGPVHQNR---------FIRQERQQQQQQQQRSEELLAERKPGPLEARERR 123
ESA L+ Q R F Q+++Q+ QQ + E+ + ++ G EA R
Sbjct: 2030 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2089
Query: 124 PSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRS 183
E E+R + + RE + R + A+ L E R ++
Sbjct: 2090 AEEAE---------EARVQ--AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2138
Query: 184 SRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRP 243
+ +E R + E + A E +K E L Q+L
Sbjct: 2139 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 244 DSRES---QEQSLVQLEATE-WRLRSGEERQDYS 273
D +++ +E ++ EATE R RS E + +S
Sbjct: 2199 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/385 (23%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 14 RRRQEEASVRGREKAE-RERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
RR +EE + +++AE RERL+++ A LE++R
Sbjct: 1346 RRMEEEERLAEQQRAEERERLAEVEA----ALEKQR------------------------ 1377
Query: 73 DESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
+ H + ER+ ++ QQ+ EE++ R+ ++A++++ S E Q
Sbjct: 1378 --------QLAEAHAQAKAQAEREAKELQQRMQEEVV-RREEAAVDAQQQKRSIQEELQQ 1428
Query: 133 SPKGRESR-EERLSPRETRER-RLGIGGAQELSLRPLEARDWRQ--SPGEVGDRSSRLSE 188
+ E+ + + E ER RL I + LEA + ++ + GE+ +R E
Sbjct: 1429 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEE 1488
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVE--SRL-SPGESAYQKLGLTEAHKWRPDS 245
A + E ER R + Q R+ EVE SR+ + E+A +K +A +
Sbjct: 1489 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1548
Query: 246 RESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE--- 302
E E+ L Q E R R + + ++ E ++TA+L +L E
Sbjct: 1549 AEEAERRLRQAEVE--RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1606
Query: 303 -----AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPE 357
+ A +A +R E+ ER ++ +W L + +A + E QK
Sbjct: 1607 VAQLREEAERRAQQQAEAERAREEAERELE-----RWQLKANEALRLRLQAEEVAQQKSL 1661
Query: 358 PPESAEKLLESPGVEA-GEGEAEKE 381
AEK E EA G+AE++
Sbjct: 1662 AQAEAEKQKEEAEREARRRGKAEEQ 1686
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/222 (22%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+E +++ Q+ +EE A ++ LE ER K + RL R +E
Sbjct: 1987 RREAEERVQKSLAAEEEAARQRKAALEEVERL-----------KAKVEEARRLRERAEQE 2035
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLS-----PGETPERSLRL 206
+ AQE + + L+A + + V + L + + S GE E + R
Sbjct: 2036 SARQLQLAQEAAQKRLQAEE-KAHAFAVQQKEQELQQTLQQEQSVLDQLRGEA-EAARRA 2093
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSG 266
AE E++ + E E+A + + EA + + S E Q Q+ Q +A +LR
Sbjct: 2094 AEEAEEARVQAE-------REAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKE 2145
Query: 267 EE----RQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQ 304
E R+ +E+ +++ K +TL ++AQ
Sbjct: 2146 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ 2187
Score = 35.4 bits (80), Expect = 0.16
Identities = 60/274 (21%), Positives = 100/274 (36%), Gaps = 24/274 (8%)
Query: 13 ARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
AR+RQ A R + ER+ + A + +R+A L + V
Sbjct: 1974 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2033
Query: 73 DESAVLLEAIGPVHQNR---------FIRQERQQQQQQQQRSEELLAERKPGPLEARERR 123
ESA L+ Q R F Q+++Q+ QQ + E+ + ++ G EA R
Sbjct: 2034 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2093
Query: 124 PSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRS 183
E E+R + + RE + R + A+ L E R ++
Sbjct: 2094 AEEAE---------EARVQ--AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2142
Query: 184 SRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRP 243
+ +E R + E + A E +K E L Q+L
Sbjct: 2143 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2202
Query: 244 DSRES---QEQSLVQLEATE-WRLRSGEERQDYS 273
D +++ +E ++ EATE R RS E + +S
Sbjct: 2203 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2236
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/385 (23%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 14 RRRQEEASVRGREKAE-RERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
RR +EE + +++AE RERL+++ A LE++R
Sbjct: 1342 RRMEEEERLAEQQRAEERERLAEVEA----ALEKQR------------------------ 1373
Query: 73 DESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
+ H + ER+ ++ QQ+ EE++ R+ ++A++++ S E Q
Sbjct: 1374 --------QLAEAHAQAKAQAEREAKELQQRMQEEVV-RREEAAVDAQQQKRSIQEELQQ 1424
Query: 133 SPKGRESR-EERLSPRETRER-RLGIGGAQELSLRPLEARDWRQ--SPGEVGDRSSRLSE 188
+ E+ + + E ER RL I + LEA + ++ + GE+ +R E
Sbjct: 1425 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEE 1484
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVE--SRL-SPGESAYQKLGLTEAHKWRPDS 245
A + E ER R + Q R+ EVE SR+ + E+A +K +A +
Sbjct: 1485 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1544
Query: 246 RESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE--- 302
E E+ L Q E R R + + ++ E ++TA+L +L E
Sbjct: 1545 AEEAERRLRQAEVE--RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1602
Query: 303 -----AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPE 357
+ A +A +R E+ ER ++ +W L + +A + E QK
Sbjct: 1603 VAQLREEAERRAQQQAEAERAREEAERELE-----RWQLKANEALRLRLQAEEVAQQKSL 1657
Query: 358 PPESAEKLLESPGVEA-GEGEAEKE 381
AEK E EA G+AE++
Sbjct: 1658 AQAEAEKQKEEAEREARRRGKAEEQ 1682
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/222 (22%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+E +++ Q+ +EE A ++ LE ER K + RL R +E
Sbjct: 1983 RREAEERVQKSLAAEEEAARQRKAALEEVERL-----------KAKVEEARRLRERAEQE 2031
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLS-----PGETPERSLRL 206
+ AQE + + L+A + + V + L + + S GE E + R
Sbjct: 2032 SARQLQLAQEAAQKRLQAEE-KAHAFAVQQKEQELQQTLQQEQSVLDQLRGEA-EAARRA 2089
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSG 266
AE E++ + E E+A + + EA + + S E Q Q+ Q +A +LR
Sbjct: 2090 AEEAEEARVQAE-------REAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKE 2141
Query: 267 EE----RQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQ 304
E R+ +E+ +++ K +TL ++AQ
Sbjct: 2142 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ 2183
Score = 35.4 bits (80), Expect = 0.16
Identities = 60/274 (21%), Positives = 100/274 (36%), Gaps = 24/274 (8%)
Query: 13 ARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
AR+RQ A R + ER+ + A + +R+A L + V
Sbjct: 1970 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2029
Query: 73 DESAVLLEAIGPVHQNR---------FIRQERQQQQQQQQRSEELLAERKPGPLEARERR 123
ESA L+ Q R F Q+++Q+ QQ + E+ + ++ G EA R
Sbjct: 2030 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2089
Query: 124 PSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRS 183
E E+R + + RE + R + A+ L E R ++
Sbjct: 2090 AEEAE---------EARVQ--AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2138
Query: 184 SRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRP 243
+ +E R + E + A E +K E L Q+L
Sbjct: 2139 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2198
Query: 244 DSRES---QEQSLVQLEATE-WRLRSGEERQDYS 273
D +++ +E ++ EATE R RS E + +S
Sbjct: 2199 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/385 (23%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 14 RRRQEEASVRGREKAE-RERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
RR +EE + +++AE RERL+++ A LE++R
Sbjct: 1310 RRMEEEERLAEQQRAEERERLAEVEA----ALEKQR------------------------ 1341
Query: 73 DESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
+ H + ER+ ++ QQ+ EE++ R+ ++A++++ S E Q
Sbjct: 1342 --------QLAEAHAQAKAQAEREAKELQQRMQEEVV-RREEAAVDAQQQKRSIQEELQQ 1392
Query: 133 SPKGRESR-EERLSPRETRER-RLGIGGAQELSLRPLEARDWRQ--SPGEVGDRSSRLSE 188
+ E+ + + E ER RL I + LEA + ++ + GE+ +R E
Sbjct: 1393 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEE 1452
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVE--SRL-SPGESAYQKLGLTEAHKWRPDS 245
A + E ER R + Q R+ EVE SR+ + E+A +K +A +
Sbjct: 1453 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1512
Query: 246 RESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE--- 302
E E+ L Q E R R + + ++ E ++TA+L +L E
Sbjct: 1513 AEEAERRLRQAEVE--RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1570
Query: 303 -----AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPE 357
+ A +A +R E+ ER ++ +W L + +A + E QK
Sbjct: 1571 VAQLREEAERRAQQQAEAERAREEAERELE-----RWQLKANEALRLRLQAEEVAQQKSL 1625
Query: 358 PPESAEKLLESPGVEA-GEGEAEKE 381
AEK E EA G+AE++
Sbjct: 1626 AQAEAEKQKEEAEREARRRGKAEEQ 1650
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/222 (22%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+E +++ Q+ +EE A ++ LE ER K + RL R +E
Sbjct: 1951 RREAEERVQKSLAAEEEAARQRKAALEEVERL-----------KAKVEEARRLRERAEQE 1999
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLS-----PGETPERSLRL 206
+ AQE + + L+A + + V + L + + S GE E + R
Sbjct: 2000 SARQLQLAQEAAQKRLQAEE-KAHAFAVQQKEQELQQTLQQEQSVLDQLRGEA-EAARRA 2057
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSG 266
AE E++ + E E+A + + EA + + S E Q Q+ Q +A +LR
Sbjct: 2058 AEEAEEARVQAE-------REAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKE 2109
Query: 267 EE----RQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQ 304
E R+ +E+ +++ K +TL ++AQ
Sbjct: 2110 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ 2151
Score = 35.4 bits (80), Expect = 0.16
Identities = 60/274 (21%), Positives = 100/274 (36%), Gaps = 24/274 (8%)
Query: 13 ARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
AR+RQ A R + ER+ + A + +R+A L + V
Sbjct: 1938 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 1997
Query: 73 DESAVLLEAIGPVHQNR---------FIRQERQQQQQQQQRSEELLAERKPGPLEARERR 123
ESA L+ Q R F Q+++Q+ QQ + E+ + ++ G EA R
Sbjct: 1998 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2057
Query: 124 PSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRS 183
E E+R + + RE + R + A+ L E R ++
Sbjct: 2058 AEEAE---------EARVQ--AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2106
Query: 184 SRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRP 243
+ +E R + E + A E +K E L Q+L
Sbjct: 2107 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2166
Query: 244 DSRES---QEQSLVQLEATE-WRLRSGEERQDYS 273
D +++ +E ++ EATE R RS E + +S
Sbjct: 2167 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2200
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/385 (23%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 14 RRRQEEASVRGREKAE-RERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
RR +EE + +++AE RERL+++ A LE++R
Sbjct: 1479 RRMEEEERLAEQQRAEERERLAEVEA----ALEKQR------------------------ 1510
Query: 73 DESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
+ H + ER+ ++ QQ+ EE++ R+ ++A++++ S E Q
Sbjct: 1511 --------QLAEAHAQAKAQAEREAKELQQRMQEEVV-RREEAAVDAQQQKRSIQEELQQ 1561
Query: 133 SPKGRESR-EERLSPRETRER-RLGIGGAQELSLRPLEARDWRQ--SPGEVGDRSSRLSE 188
+ E+ + + E ER RL I + LEA + ++ + GE+ +R E
Sbjct: 1562 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEE 1621
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVE--SRL-SPGESAYQKLGLTEAHKWRPDS 245
A + E ER R + Q R+ EVE SR+ + E+A +K +A +
Sbjct: 1622 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1681
Query: 246 RESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE--- 302
E E+ L Q E R R + + ++ E ++TA+L +L E
Sbjct: 1682 AEEAERRLRQAEVE--RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1739
Query: 303 -----AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPE 357
+ A +A +R E+ ER ++ +W L + +A + E QK
Sbjct: 1740 VAQLREEAERRAQQQAEAERAREEAERELE-----RWQLKANEALRLRLQAEEVAQQKSL 1794
Query: 358 PPESAEKLLESPGVEA-GEGEAEKE 381
AEK E EA G+AE++
Sbjct: 1795 AQAEAEKQKEEAEREARRRGKAEEQ 1819
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/222 (22%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+E +++ Q+ +EE A ++ LE ER K + RL R +E
Sbjct: 2120 RREAEERVQKSLAAEEEAARQRKAALEEVERL-----------KAKVEEARRLRERAEQE 2168
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLS-----PGETPERSLRL 206
+ AQE + + L+A + + V + L + + S GE E + R
Sbjct: 2169 SARQLQLAQEAAQKRLQAEE-KAHAFAVQQKEQELQQTLQQEQSVLDQLRGEA-EAARRA 2226
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSG 266
AE E++ + E E+A + + EA + + S E Q Q+ Q +A +LR
Sbjct: 2227 AEEAEEARVQAE-------REAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKE 2278
Query: 267 EE----RQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQ 304
E R+ +E+ +++ K +TL ++AQ
Sbjct: 2279 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ 2320
Score = 35.4 bits (80), Expect = 0.16
Identities = 60/274 (21%), Positives = 100/274 (36%), Gaps = 24/274 (8%)
Query: 13 ARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
AR+RQ A R + ER+ + A + +R+A L + V
Sbjct: 2107 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2166
Query: 73 DESAVLLEAIGPVHQNR---------FIRQERQQQQQQQQRSEELLAERKPGPLEARERR 123
ESA L+ Q R F Q+++Q+ QQ + E+ + ++ G EA R
Sbjct: 2167 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2226
Query: 124 PSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRS 183
E E+R + + RE + R + A+ L E R ++
Sbjct: 2227 AEEAE---------EARVQ--AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2275
Query: 184 SRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRP 243
+ +E R + E + A E +K E L Q+L
Sbjct: 2276 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2335
Query: 244 DSRES---QEQSLVQLEATE-WRLRSGEERQDYS 273
D +++ +E ++ EATE R RS E + +S
Sbjct: 2336 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2369
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/385 (23%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 14 RRRQEEASVRGREKAE-RERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
RR +EE + +++AE RERL+++ A LE++R
Sbjct: 1320 RRMEEEERLAEQQRAEERERLAEVEA----ALEKQR------------------------ 1351
Query: 73 DESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
+ H + ER+ ++ QQ+ EE++ R+ ++A++++ S E Q
Sbjct: 1352 --------QLAEAHAQAKAQAEREAKELQQRMQEEVV-RREEAAVDAQQQKRSIQEELQQ 1402
Query: 133 SPKGRESR-EERLSPRETRER-RLGIGGAQELSLRPLEARDWRQ--SPGEVGDRSSRLSE 188
+ E+ + + E ER RL I + LEA + ++ + GE+ +R E
Sbjct: 1403 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEE 1462
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVE--SRL-SPGESAYQKLGLTEAHKWRPDS 245
A + E ER R + Q R+ EVE SR+ + E+A +K +A +
Sbjct: 1463 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1522
Query: 246 RESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE--- 302
E E+ L Q E R R + + ++ E ++TA+L +L E
Sbjct: 1523 AEEAERRLRQAEVE--RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1580
Query: 303 -----AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPE 357
+ A +A +R E+ ER ++ +W L + +A + E QK
Sbjct: 1581 VAQLREEAERRAQQQAEAERAREEAERELE-----RWQLKANEALRLRLQAEEVAQQKSL 1635
Query: 358 PPESAEKLLESPGVEA-GEGEAEKE 381
AEK E EA G+AE++
Sbjct: 1636 AQAEAEKQKEEAEREARRRGKAEEQ 1660
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/222 (22%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+E +++ Q+ +EE A ++ LE ER K + RL R +E
Sbjct: 1961 RREAEERVQKSLAAEEEAARQRKAALEEVERL-----------KAKVEEARRLRERAEQE 2009
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLS-----PGETPERSLRL 206
+ AQE + + L+A + + V + L + + S GE E + R
Sbjct: 2010 SARQLQLAQEAAQKRLQAEE-KAHAFAVQQKEQELQQTLQQEQSVLDQLRGEA-EAARRA 2067
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSG 266
AE E++ + E E+A + + EA + + S E Q Q+ Q +A +LR
Sbjct: 2068 AEEAEEARVQAE-------REAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKE 2119
Query: 267 EE----RQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQ 304
E R+ +E+ +++ K +TL ++AQ
Sbjct: 2120 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ 2161
Score = 35.4 bits (80), Expect = 0.16
Identities = 60/274 (21%), Positives = 100/274 (36%), Gaps = 24/274 (8%)
Query: 13 ARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
AR+RQ A R + ER+ + A + +R+A L + V
Sbjct: 1948 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2007
Query: 73 DESAVLLEAIGPVHQNR---------FIRQERQQQQQQQQRSEELLAERKPGPLEARERR 123
ESA L+ Q R F Q+++Q+ QQ + E+ + ++ G EA R
Sbjct: 2008 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2067
Query: 124 PSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRS 183
E E+R + + RE + R + A+ L E R ++
Sbjct: 2068 AEEAE---------EARVQ--AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2116
Query: 184 SRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRP 243
+ +E R + E + A E +K E L Q+L
Sbjct: 2117 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2176
Query: 244 DSRES---QEQSLVQLEATE-WRLRSGEERQDYS 273
D +++ +E ++ EATE R RS E + +S
Sbjct: 2177 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2210
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/385 (23%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 14 RRRQEEASVRGREKAE-RERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
RR +EE + +++AE RERL+++ A LE++R
Sbjct: 1328 RRMEEEERLAEQQRAEERERLAEVEA----ALEKQR------------------------ 1359
Query: 73 DESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
+ H + ER+ ++ QQ+ EE++ R+ ++A++++ S E Q
Sbjct: 1360 --------QLAEAHAQAKAQAEREAKELQQRMQEEVV-RREEAAVDAQQQKRSIQEELQQ 1410
Query: 133 SPKGRESR-EERLSPRETRER-RLGIGGAQELSLRPLEARDWRQ--SPGEVGDRSSRLSE 188
+ E+ + + E ER RL I + LEA + ++ + GE+ +R E
Sbjct: 1411 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEE 1470
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVE--SRL-SPGESAYQKLGLTEAHKWRPDS 245
A + E ER R + Q R+ EVE SR+ + E+A +K +A +
Sbjct: 1471 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1530
Query: 246 RESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE--- 302
E E+ L Q E R R + + ++ E ++TA+L +L E
Sbjct: 1531 AEEAERRLRQAEVE--RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1588
Query: 303 -----AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPE 357
+ A +A +R E+ ER ++ +W L + +A + E QK
Sbjct: 1589 VAQLREEAERRAQQQAEAERAREEAERELE-----RWQLKANEALRLRLQAEEVAQQKSL 1643
Query: 358 PPESAEKLLESPGVEA-GEGEAEKE 381
AEK E EA G+AE++
Sbjct: 1644 AQAEAEKQKEEAEREARRRGKAEEQ 1668
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/222 (22%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+E +++ Q+ +EE A ++ LE ER K + RL R +E
Sbjct: 1969 RREAEERVQKSLAAEEEAARQRKAALEEVERL-----------KAKVEEARRLRERAEQE 2017
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLS-----PGETPERSLRL 206
+ AQE + + L+A + + V + L + + S GE E + R
Sbjct: 2018 SARQLQLAQEAAQKRLQAEE-KAHAFAVQQKEQELQQTLQQEQSVLDQLRGEA-EAARRA 2075
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSG 266
AE E++ + E E+A + + EA + + S E Q Q+ Q +A +LR
Sbjct: 2076 AEEAEEARVQAE-------REAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKE 2127
Query: 267 EE----RQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQ 304
E R+ +E+ +++ K +TL ++AQ
Sbjct: 2128 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ 2169
Score = 35.4 bits (80), Expect = 0.16
Identities = 60/274 (21%), Positives = 100/274 (36%), Gaps = 24/274 (8%)
Query: 13 ARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
AR+RQ A R + ER+ + A + +R+A L + V
Sbjct: 1956 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2015
Query: 73 DESAVLLEAIGPVHQNR---------FIRQERQQQQQQQQRSEELLAERKPGPLEARERR 123
ESA L+ Q R F Q+++Q+ QQ + E+ + ++ G EA R
Sbjct: 2016 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2075
Query: 124 PSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRS 183
E E+R + + RE + R + A+ L E R ++
Sbjct: 2076 AEEAE---------EARVQ--AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2124
Query: 184 SRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRP 243
+ +E R + E + A E +K E L Q+L
Sbjct: 2125 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2184
Query: 244 DSRES---QEQSLVQLEATE-WRLRSGEERQDYS 273
D +++ +E ++ EATE R RS E + +S
Sbjct: 2185 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2218
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 50.8 bits (120), Expect = 4e-06
Identities = 90/385 (23%), Positives = 157/385 (40%), Gaps = 61/385 (15%)
Query: 14 RRRQEEASVRGREKAE-RERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
RR +EE + +++AE RERL+++ A LE++R
Sbjct: 1369 RRMEEEERLAEQQRAEERERLAEVEA----ALEKQR------------------------ 1400
Query: 73 DESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
+ H + ER+ ++ QQ+ EE++ R+ ++A++++ S E Q
Sbjct: 1401 --------QLAEAHAQAKAQAEREAKELQQRMQEEVV-RREEAAVDAQQQKRSIQEELQQ 1451
Query: 133 SPKGRESR-EERLSPRETRER-RLGIGGAQELSLRPLEARDWRQ--SPGEVGDRSSRLSE 188
+ E+ + + E ER RL I + LEA + ++ + GE+ +R E
Sbjct: 1452 LRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEE 1511
Query: 189 AWKWRLSPGETPERSLRLAESREQSPRRKEVE--SRL-SPGESAYQKLGLTEAHKWRPDS 245
A + E ER R + Q R+ EVE SR+ + E+A +K +A +
Sbjct: 1512 AEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQ 1571
Query: 246 RESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSETLTRE--- 302
E E+ L Q E R R + + ++ E ++TA+L +L E
Sbjct: 1572 AEEAERRLRQAEVE--RARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVA 1629
Query: 303 -----AQGNSSAGVEAAEQRPVEDGERGMKPTEGWKWTLNSGKAREWTPRDIEAQTQKPE 357
+ A +A +R E+ ER ++ +W L + +A + E QK
Sbjct: 1630 VAQLREEAERRAQQQAEAERAREEAERELE-----RWQLKANEALRLRLQAEEVAQQKSL 1684
Query: 358 PPESAEKLLESPGVEA-GEGEAEKE 381
AEK E EA G+AE++
Sbjct: 1685 AQAEAEKQKEEAEREARRRGKAEEQ 1709
Score = 35.8 bits (81), Expect = 0.12
Identities = 51/222 (22%), Positives = 91/222 (40%), Gaps = 30/222 (13%)
Query: 92 RQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRE 151
R+E +++ Q+ +EE A ++ LE ER K + RL R +E
Sbjct: 2010 RREAEERVQKSLAAEEEAARQRKAALEEVERL-----------KAKVEEARRLRERAEQE 2058
Query: 152 RRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLS-----PGETPERSLRL 206
+ AQE + + L+A + + V + L + + S GE E + R
Sbjct: 2059 SARQLQLAQEAAQKRLQAEE-KAHAFAVQQKEQELQQTLQQEQSVLDQLRGEA-EAARRA 2116
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSG 266
AE E++ + E E+A + + EA + + S E Q Q+ Q +A +LR
Sbjct: 2117 AEEAEEARVQAE-------REAAQSRRQVEEAERLK-QSAEEQAQARAQAQAAAEKLRKE 2168
Query: 267 EE----RQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQ 304
E R+ +E+ +++ K +TL ++AQ
Sbjct: 2169 AEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQ 2210
Score = 35.4 bits (80), Expect = 0.16
Identities = 60/274 (21%), Positives = 100/274 (36%), Gaps = 24/274 (8%)
Query: 13 ARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDP 72
AR+RQ A R + ER+ + A + +R+A L + V
Sbjct: 1997 ARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAE 2056
Query: 73 DESAVLLEAIGPVHQNR---------FIRQERQQQQQQQQRSEELLAERKPGPLEARERR 123
ESA L+ Q R F Q+++Q+ QQ + E+ + ++ G EA R
Sbjct: 2057 QESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRA 2116
Query: 124 PSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRS 183
E E+R + + RE + R + A+ L E R ++
Sbjct: 2117 AEEAE---------EARVQ--AEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKL 2165
Query: 184 SRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRP 243
+ +E R + E + A E +K E L Q+L
Sbjct: 2166 RKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEET 2225
Query: 244 DSRES---QEQSLVQLEATE-WRLRSGEERQDYS 273
D +++ +E ++ EATE R RS E + +S
Sbjct: 2226 DHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2259
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 50.1 bits (118), Expect = 6e-06
Identities = 47/210 (22%), Positives = 92/210 (43%), Gaps = 35/210 (16%)
Query: 87 QNRFIRQERQ--QQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERL 144
+ + RQE +++++ +R EE++ E++ E E+ ++R+Q K +E EE++
Sbjct: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE--EEKI 419
Query: 145 SPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWK--WRLSPGETPER 202
+E R+ + EA+ WRQ ++ ++ ++ E K WR +
Sbjct: 420 REQEKRQEQ--------------EAKMWRQEE-KIREQEEKIREQEKKMWRQEEKIHEQE 464
Query: 203 SLRLAESREQSPRRKEVESRLSPGESAY----------QKLGLTEAHKWRPDSR-ESQEQ 251
+R E R++ E ++ E + +K+ E WR + + QE+
Sbjct: 465 KIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEE 524
Query: 252 SLVQLEATEWRLRSGEERQDYSEECGRKEE 281
+ + E WR EE+ EE R+EE
Sbjct: 525 KIREQEEKMWR---QEEKIREQEEMWREEE 551
Score = 44.3 bits (103), Expect = 3e-04
Identities = 76/293 (25%), Positives = 123/293 (41%), Gaps = 36/293 (12%)
Query: 3 TIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVL 62
TI D +L+ + QE+ + EK+E + + KR L RAKL L P L
Sbjct: 213 TITDEELKEKNAKLQEKLQLVESEKSEIQL--NVKELKRKL---ERAKLLL----PQQQL 263
Query: 63 GTVEAGPPDPDESAVLLEAIGPVHQNR-FIRQERQQQQQQQQRSEELLAERKPGPLEARE 121
EA + +V + V +N + R +QQ+++ R EE + E + E E
Sbjct: 264 -QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM-WRQEEKIQEWEEKIQEQEE 321
Query: 122 R-RPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVG 180
+ R ++R+Q K R E E R+ + +E +R E W E
Sbjct: 322 KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW-----EKE 376
Query: 181 DRSSRLSE-AWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAH 239
++ R E W+ E E+ + REQ +R+E E ++ E ++ EA
Sbjct: 377 EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQ----EAK 431
Query: 240 KWRPDSR-ESQEQSLVQLEATEWR----------LRSGEERQDYSEECGRKEE 281
WR + + QE+ + + E WR +R E+RQ+ EE R+EE
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQE-QEEMWRQEE 483
Score = 41.2 bits (95), Expect = 0.003
Identities = 70/344 (20%), Positives = 134/344 (38%), Gaps = 51/344 (14%)
Query: 15 RRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPDE 74
RRQEE EK E+ R + W++ RR+ ++ E + E + +E
Sbjct: 338 RRQEEMMW---EKEEKMRRQEEMMWEKEEKMRRQEEM---MWEKEEKMRRQEEMMWEKEE 391
Query: 75 SAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSP 134
LE +H+ IR++ +++Q++++ E+ + + + +E + +R+Q
Sbjct: 392 KIRELEE--KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK-----IREQEE 444
Query: 135 KGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRL 194
K RE ++ E + I +E R + WRQ ++ E W+ +
Sbjct: 445 KIREQEKKMWRQEEKIHEQEKI---REEEKRQEQEEMWRQE-----EKIHEQEEIWRQKE 496
Query: 195 SPGETPERSLRLAES--------REQSPRRKEVESRLSPGESAY---------------- 230
E E+ + E REQ + +E E ++ E
Sbjct: 497 KMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQ 556
Query: 231 QKLGLTEAHKWRPDSRESQEQSLVQLEATEWR----LRSGEERQDYSEECGRKEEWPVPG 286
+K+ E + + D QE+ + + E WR +R EE++ EE K+E +
Sbjct: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIR- 615
Query: 287 VAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTE 330
+E + E RE + E +++ + GE+ K E
Sbjct: 616 -EQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 658
Score = 35.8 bits (81), Expect = 0.12
Identities = 50/247 (20%), Positives = 91/247 (36%), Gaps = 50/247 (20%)
Query: 85 VHQNRFIRQERQQQQQQQQ----------RSEELLAERKPGPLEARERRPSPGE-MRDQS 133
+H+ I +++++ +Q++ R EE + E++ E E+ E +R+Q
Sbjct: 485 IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQE 544
Query: 134 PKGRESR----EERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPG---EVGDRSSRL 186
RE +E++ E R+ + QE +R E + WRQ + R +
Sbjct: 545 EMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQE 604
Query: 187 SEAWKWRLSPGETPERSLRLAES--------REQSPRRKEVESRLSPGESAY----QKLG 234
+ WK E E+ E REQ +E E ++ E +K+
Sbjct: 605 EKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
Query: 235 LTEAHKWRPDSR---------------ESQEQSLVQLEATEWR-----LRSGEERQDYSE 274
E WR + + QE+ + + E W E+ Q+ E
Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724
Query: 275 ECGRKEE 281
+ R+EE
Sbjct: 725 KMRRQEE 731
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 50.1 bits (118), Expect = 6e-06
Identities = 77/332 (23%), Positives = 137/332 (41%), Gaps = 28/332 (8%)
Query: 3 TIPDWKLQLLARRRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVL 62
TI D +L+ + QE+ + EK+E + + KR L RAKL L P L
Sbjct: 201 TITDEELKEKNAKLQEKLQLVESEKSEIQL--NVKELKRKL---ERAKLLL----PQQQL 251
Query: 63 GTVEAGPPDPDESAVLLEAIGPVHQNRFIRQERQQQQQQQQRSEELLAERKPGPLEARER 122
EA + +V + V +N + QQQ+++ R EE + ER+ E E+
Sbjct: 252 -QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEK 310
Query: 123 RPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGDR 182
+R+Q K R E E R+ + +E +R LE + Q ++ ++
Sbjct: 311 ------IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE--KIREQ 362
Query: 183 SSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQ----KLGLTEA 238
+ E K R E +R + A+ Q + +E E ++ E Q K+G E
Sbjct: 363 EEKRQEEEKIR----EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 418
Query: 239 HKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWPVPGVAPKETAELSET 298
W + E QEQ ++ E ++R E++ EE R++E + K + +
Sbjct: 419 KMWEQE-EEMQEQE-EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKM 476
Query: 299 LTREAQGNSSAGVEAAEQRPVEDGERGMKPTE 330
+EA+ ++ + + E+ ++ E
Sbjct: 477 CEQEAKMQEQEEKMRRQEEKIREQEKKIREQE 508
Score = 41.6 bits (96), Expect = 0.002
Identities = 59/281 (20%), Positives = 112/281 (39%), Gaps = 26/281 (9%)
Query: 7 WKLQLLARRRQE---EASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLG 63
W+ + + R+E E + RE+ E+ R + W++ RR+ ++ E L
Sbjct: 291 WRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIREL- 349
Query: 64 TVEAGPPDPDESAVLLEAIGPVHQNRFIRQE--RQQQQQQQQRSEELLAERKPGPLEARE 121
E + E + IR++ RQ+Q+ + R EE + E++ E E
Sbjct: 350 -----EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE 404
Query: 122 RRPSPGEMRDQSPKGRESREERLSPRETRERRLGIGGAQELSLRPLEARDWRQSPGEVGD 181
E + + +EE + +E + RR QE +R E + R+ ++ +
Sbjct: 405 MMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRR------QEEKIREQEKKI-REQEEKIRE 457
Query: 182 RSSRLSEAW-KWRLSPGETPERSLRLAESREQSPRRKEVESRLSPGESAYQKLGLTEAHK 240
+ + E K G+ E+ ++ E E+ R++E ++ E ++ + K
Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE---KIREQEKKIRE----QEEK 510
Query: 241 WRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEE 281
R QEQ E E E+ Q+ E+ R+EE
Sbjct: 511 IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 551
Score = 32.0 bits (71), Expect = 1.7
Identities = 35/141 (24%), Positives = 67/141 (47%), Gaps = 15/141 (10%)
Query: 15 RRQEEASVRGREKAERERLSQMPAWKRGLLERRRAKLGLSPGEPSPVLGTVEAGPPDPDE 74
RRQEE +R +EK RE+ ++ + +++ + K+G G+ + EA + +E
Sbjct: 435 RRQEE-KIREQEKKIREQEEKIREQEE-MMQEQEEKMGEQEGK----MCEQEAKMQEQEE 488
Query: 75 SAVLLEAIGPVHQNRFIRQERQ--QQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQ 132
E + + QE + +Q++ Q EE + E++ E E+ M++Q
Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEK------MQEQ 542
Query: 133 SPKGRESREERLSPRETRERR 153
K R +EE++ +E R R+
Sbjct: 543 EEKMRR-QEEKMREQEVRLRQ 562
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 50.1 bits (118), Expect = 6e-06
Identities = 40/119 (33%), Positives = 50/119 (42%), Gaps = 16/119 (13%)
Query: 402 PLPPEDAGTGGLRQQEEEAVELQPPP--PAPLSPPP-PAP----TAPQPPGDPLMSRLFY 454
P+PP QQ+++ QPPP P P PPP P P P PP D +
Sbjct: 59 PIPPPPP-----HQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQ 113
Query: 455 GVKAGPGVGA--PRRSGHTFTVNPRRSVPPAT--PATPTSPATVDAAVPGAGKKRYPTA 509
G PGVG+ P S P PP + TPT P V +A PGA P++
Sbjct: 114 GPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSS 172
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/136 (27%), Positives = 50/136 (36%), Gaps = 18/136 (13%)
Query: 352 QTQKPEPPESAEK--LLESPGVEAGEGEAEKEEAGA-------QGRPLRALQNCCSVPSP 402
Q Q P PP+ + K + + PG G G A + A G P + P P
Sbjct: 96 QQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPP 155
Query: 403 L--------PPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFY 454
PP + G+ +A PPPPA + P P P PG P ++
Sbjct: 156 AVTSAPPGAPPPTPPSSGVPTTPPQAGG-PPPPPAAVPGPGPGPKQGPGPGGPKGGKMPG 214
Query: 455 GVKAGPGVGAPRRSGH 470
G K G G G GH
Sbjct: 215 GPKPGGGPGLSTPGGH 230
Score = 38.1 bits (87), Expect = 0.024
Identities = 33/111 (29%), Positives = 41/111 (36%), Gaps = 12/111 (10%)
Query: 400 PSPLPPEDAGTGGLRQQEEEAVELQPPPPAPLSPPPPAPTAPQPPGDPLMSRLFYGVKAG 459
P P P + Q + V Q P PAP P ++ PP P S G G
Sbjct: 89 PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTS----GAPPG 144
Query: 460 PGVGAPRRSGHTFTVNPRRSVPPATPAT--PTSPATV------DAAVPGAG 502
G G T P + PP P++ PT+P AAVPG G
Sbjct: 145 SGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPG 195
Score = 37.4 bits (85), Expect = 0.041
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 12/91 (13%)
Query: 86 HQNRFIRQERQQQQQQQQRSEEL----LAERKPGPL---EARERRPSP-----GEMRDQS 133
HQ +RQ+ ++Q++ +R EEL + +RK L E R RR EM +Q
Sbjct: 530 HQANLLRQDLMRRQEELRRMEELHNQEMQKRKEMQLRQEEERRRREEEMMIRQREMEEQM 589
Query: 134 PKGRESREERLSPRETRERRLGIGGAQELSL 164
+ RE R+ + RER + +GG +++
Sbjct: 590 RRQREESYSRMGYMDPRERDMRMGGGGAMNM 620
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 49.7 bits (117), Expect = 8e-06
Identities = 53/198 (26%), Positives = 82/198 (41%), Gaps = 12/198 (6%)
Query: 95 RQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRERRL 154
RQQ++++++R EE LA RK R+R R + + R+ +EE L E R R
Sbjct: 765 RQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREE 824
Query: 155 GIGGAQELSLRPL--EARDWRQSPGEVGDR--SSRL---SEAWKWRLSPGETPERSLRLA 207
QE LR EA W + E R +RL EA + R E + L +
Sbjct: 825 EERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQ 884
Query: 208 ESRE---QSPRRKEVESRLSPGESAYQ--KLGLTEAHKWRPDSRESQEQSLVQLEATEWR 262
+E Q +++E RL + Q ++ L + W S + QS L E +
Sbjct: 885 RQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQ 944
Query: 263 LRSGEERQDYSEECGRKE 280
E + EE R++
Sbjct: 945 KLEEERERQLREEQRRQQ 962
Score = 46.2 bits (108), Expect = 9e-05
Identities = 73/316 (23%), Positives = 128/316 (40%), Gaps = 31/316 (9%)
Query: 91 IRQERQQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETR 150
+ QER++ + + +R EE ERK + RR +R Q + R+ REE R +
Sbjct: 731 LEQERREAEMRAKREEE---ERKR---QEELRRQQEEILRRQQEEERKRREEEELARRKQ 784
Query: 151 ERRLGIGGAQELSLRPLEARDWRQSPGE----VGDRSSRLSEAWKWRLSPGETPERSLRL 206
E L QE++LR + RQ E + +R E K + E + +
Sbjct: 785 EEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKW 844
Query: 207 AESREQSPRRKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSG 266
A E++ RR E E+RL E A + E K + + Q++ + Q + + LR
Sbjct: 845 AREEEEAQRRLE-ENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRL 903
Query: 267 EERQDYSEECGRKEEWPVPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGM 326
+++Q + K P + ++ T Q S A + AE + +E+
Sbjct: 904 QQQQQQQQLAQMK--------LPSSSTWGQQSNTTACQ--SQATLSLAEIQKLEEERERQ 953
Query: 327 KPTEGWKWTLNSGKAREWTPRDIEAQTQK-------PEPPESAEKLLESPGVEAGEGEAE 379
E + KA + + + Q QK +P + + LLE EA + + +
Sbjct: 954 LREEQRRQQRELMKALQ---QQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQ 1010
Query: 380 KEEAGAQGRPLRALQN 395
+++ +P RA N
Sbjct: 1011 QQQQQQHQQPNRARNN 1026
Score = 45.8 bits (107), Expect = 1e-04
Identities = 51/190 (26%), Positives = 83/190 (43%), Gaps = 24/190 (12%)
Query: 96 QQQQQQQQRSEELLAERKPGPLEARERRPSPGEMRDQSPKGRESREERLSPRETRERRLG 155
Q QQ ++ ++ +L ER+ + A+ E R + + R +EE L ++ ER+
Sbjct: 719 QLQQLEKAKAAKLEQERREAEMRAKREE----EERKRQEELRRQQEEILRRQQEEERKR- 773
Query: 156 IGGAQELSLRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPR 215
+EL+ R E RQ E+ R R E + + E RL E R +
Sbjct: 774 -REEEELARRKQEEALRRQREQEIALRRQREEEERQ------QQEEALRRLEERRREEEE 826
Query: 216 RKEVESRLSPGESAYQKLGLTEAHKWRPDSRESQ---EQSLVQLEATEWRLRSGEERQDY 272
R++ E L E EA KW + E+Q E++ +++E RLR EE +
Sbjct: 827 RRKQEELLRKQEE--------EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKR 878
Query: 273 SE-ECGRKEE 281
E E R++E
Sbjct: 879 KELEVQRQKE 888
Score = 33.1 bits (74), Expect = 0.77
Identities = 43/167 (25%), Positives = 61/167 (36%), Gaps = 7/167 (4%)
Query: 164 LRPLEARDWRQSPGEVGDRSSRLSEAWKWRLSPGETPERSLRLAESREQSPRRKEVESRL 223
L +A Q E R+ R E K + E LR + E+ RR+E E
Sbjct: 723 LEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILR-RQQEEERKRREEEELAR 781
Query: 224 SPGESAYQKLGLTEAHKWRPDSRESQEQSLVQLEATEWRLRSGEERQDYSEECGRKEEWP 283
E A ++ E R E ++Q L E R R EER+ E ++EE
Sbjct: 782 RKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEA 841
Query: 284 VPGVAPKETAELSETLTREAQGNSSAGVEAAEQRPVEDGERGMKPTE 330
+E A+ R + N E A + E+ ER K E
Sbjct: 842 AKWAREEEEAQ------RRLEENRLRMEEEAARLRHEEEERKRKELE 882
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.129 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,346,792
Number of Sequences: 37866
Number of extensions: 2133318
Number of successful extensions: 35369
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 488
Number of HSP's successfully gapped in prelim test: 1460
Number of HSP's that attempted gapping in prelim test: 16414
Number of HSP's gapped (non-prelim): 10841
length of query: 613
length of database: 18,247,518
effective HSP length: 108
effective length of query: 505
effective length of database: 14,157,990
effective search space: 7149784950
effective search space used: 7149784950
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.