Guide to the Human Genome
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Search of human proteins with 19923272

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|19923272 xenotropic and polytropic retrovirus receptor
isoform 1 [Homo sapiens]
         (696 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|19923272 xenotropic and polytropic retrovirus receptor isofor...  1419   0.0  
gi|208609982 xenotropic and polytropic retrovirus receptor isofo...   885   0.0  
gi|110825982 hect domain and RLD 5 [Homo sapiens]                      38   0.028
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]          37   0.047
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]          37   0.047
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]          37   0.047
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         37   0.081
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         37   0.081
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   36   0.14 
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]         35   0.18 
gi|61563742 hect domain and RLD 6 [Homo sapiens]                       35   0.18 
gi|5174457 kinetochore associated 2 [Homo sapiens]                     32   1.5  
gi|27436948 lamin A/C isoform 3 [Homo sapiens]                         32   2.0  
gi|5031875 lamin A/C isoform 2 [Homo sapiens]                          32   2.0  
gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens]               32   2.0  
gi|148271104 patched domain containing 1 [Homo sapiens]                32   2.6  
gi|14150134 coiled-coil-helix-coiled-coil-helix domain containin...    31   4.4  
gi|75677351 suppressor of defective silencing 3 [Homo sapiens]         31   4.4  
gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo sa...    31   4.4  
gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo s...    31   4.4  
gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo s...    31   4.4  
gi|50083279 centrosome protein 4 [Homo sapiens]                        30   5.8  
gi|66773038 cell division cycle 37 homolog (S. cerevisiae)-like ...    30   5.8  
gi|4507011 glucose transporter 4 [Homo sapiens]                        30   7.6  
gi|122937514 unc-13 homolog C [Homo sapiens]                           30   7.6  
gi|210147514 ring finger protein 187 [Homo sapiens]                    30   7.6  
gi|166795299 solute carrier family 2 (facilitated glucose transp...    30   9.9  
gi|25121987 non-SMC condensin I complex, subunit H [Homo sapiens]      30   9.9  

>gi|19923272 xenotropic and polytropic retrovirus receptor isoform 1
           [Homo sapiens]
          Length = 696

 Score = 1419 bits (3672), Expect = 0.0
 Identities = 696/696 (100%), Positives = 696/696 (100%)

Query: 1   MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQ 60
           MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQ
Sbjct: 1   MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQ 60

Query: 61  TCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHE 120
           TCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHE
Sbjct: 61  TCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHE 120

Query: 121 ERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV 180
           ERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV
Sbjct: 121 ERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV 180

Query: 181 EVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF 240
           EVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
Sbjct: 181 EVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF 240

Query: 241 CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHV 300
           CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHV
Sbjct: 241 CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHV 300

Query: 301 LIFELNPRSNLSHQHLFEIAGFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLI 360
           LIFELNPRSNLSHQHLFEIAGFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLI
Sbjct: 301 LIFELNPRSNLSHQHLFEIAGFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLI 360

Query: 361 NPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSLE 420
           NPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSLE
Sbjct: 361 NPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSLE 420

Query: 421 LKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA 480
           LKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA
Sbjct: 421 LKWDESKGLLPNNSEESGICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDTKRAFPHLVNA 480

Query: 481 GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKN 540
           GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKN
Sbjct: 481 GKYSTTFFMVTFAALYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKN 540

Query: 541 AGENTFLREEIVYPQKAYYYCAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLE 600
           AGENTFLREEIVYPQKAYYYCAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLE
Sbjct: 541 AGENTFLREEIVYPQKAYYYCAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLE 600

Query: 601 VFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQDDGVRNRQKNRS 660
           VFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQDDGVRNRQKNRS
Sbjct: 601 VFRRFVWNFFRLENEHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQDDGVRNRQKNRS 660

Query: 661 WKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT 696
           WKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT
Sbjct: 661 WKYNQSISLRRPRLASQSKARDTKVLIEDTDDEANT 696


>gi|208609982 xenotropic and polytropic retrovirus receptor isoform
           2 [Homo sapiens]
          Length = 631

 Score =  885 bits (2287), Expect = 0.0
 Identities = 437/438 (99%), Positives = 437/438 (99%)

Query: 1   MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQ 60
           MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQ
Sbjct: 1   MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQ 60

Query: 61  TCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHE 120
           TCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHE
Sbjct: 61  TCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHE 120

Query: 121 ERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV 180
           ERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV
Sbjct: 121 ERVQHRNIKDLKLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV 180

Query: 181 EVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF 240
           EVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF
Sbjct: 181 EVAPFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRVPPLGAAQPAPAWTTFRVGLF 240

Query: 241 CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHV 300
           CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHV
Sbjct: 241 CGIFIVLNITLVLAAVFKLETDRSIWPLIRIYRGGFLLIEFLFLLGINTYGWRQAGVNHV 300

Query: 301 LIFELNPRSNLSHQHLFEIAGFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLI 360
           LIFELNPRSNLSHQHLFEIAGFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLI
Sbjct: 301 LIFELNPRSNLSHQHLFEIAGFLGILWCLSLLACFFAPISVIPTYVYPLALYGFMVFFLI 360

Query: 361 NPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSLE 420
           NPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSLE
Sbjct: 361 NPTKTFYYKSRFWLLKLLFRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSLE 420

Query: 421 LKWDESKGLLPNNSEESG 438
           LKWDESKGLLPNNSEE G
Sbjct: 421 LKWDESKGLLPNNSEERG 438



 Score =  405 bits (1042), Expect = e-113
 Identities = 197/202 (97%), Positives = 199/202 (98%)

Query: 495 LYSTHKERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYP 554
           L +  +ERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYP
Sbjct: 430 LPNNSEERGHSDTMVFFYLWIVFYIISSCYTLIWDLKMDWGLFDKNAGENTFLREEIVYP 489

Query: 555 QKAYYYCAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLEN 614
           QKAYYYCAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLEN
Sbjct: 490 QKAYYYCAIIEDVILRFAWTIQISITSTTLLPHSGDIIATVFAPLEVFRRFVWNFFRLEN 549

Query: 615 EHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRL 674
           EHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRL
Sbjct: 550 EHLNNCGEFRAVRDISVAPLNADDQTLLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRL 609

Query: 675 ASQSKARDTKVLIEDTDDEANT 696
           ASQSKARDTKVLIEDTDDEANT
Sbjct: 610 ASQSKARDTKVLIEDTDDEANT 631


>gi|110825982 hect domain and RLD 5 [Homo sapiens]
          Length = 1024

 Score = 38.1 bits (87), Expect = 0.028
 Identities = 22/103 (21%), Positives = 50/103 (48%), Gaps = 12/103 (11%)

Query: 45  DTVKRYFAKFEEKFFQTCEKELAKI------------NTFYSEKLAEAQRRFATLQNELQ 92
           D+VK  + +F   F++ C++++ K+            NT Y  K  E   R+    N   
Sbjct: 875 DSVKAVYEEFRRGFYKMCDEDIIKLFHPEELKDVIVGNTDYDWKTFEKNARYEPGYNSSH 934

Query: 93  SSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAF 135
            ++    ++    TL +++K +  L+  +R+Q +++ ++K+ F
Sbjct: 935 PTIVMFWKAFHKLTLEEKKKFLVFLTGTDRLQMKDLNNMKITF 977


>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
          Length = 445

 Score = 37.4 bits (85), Expect = 0.047
 Identities = 45/201 (22%), Positives = 84/201 (41%), Gaps = 15/201 (7%)

Query: 8   SAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELA 67
           +++I  + R     YEA  D L   Q Q    +V ++  +K      +E   +   +   
Sbjct: 185 NSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQ-LLKMKVESSQEANAEVMREMTK 243

Query: 68  KINTFYSEKLAEAQRRFAT----LQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERV 123
           K+ + Y EKL E QR+ +     L  E  S L A +E+        ++     +S EE+ 
Sbjct: 244 KLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEAN-------KKMQAAEISLEEKD 296

Query: 124 QHRNIKDLKLAFSE---FYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV 180
           Q     D  +   E     L L LL++   ++        +++ ++ E S     R+ H+
Sbjct: 297 QRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHL 356

Query: 181 EVAPFYTCKKINQLISETEAV 201
           +       KK+ Q++ E E++
Sbjct: 357 DDMVHCQQKKVKQMVEEIESL 377


>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
          Length = 550

 Score = 37.4 bits (85), Expect = 0.047
 Identities = 45/201 (22%), Positives = 84/201 (41%), Gaps = 15/201 (7%)

Query: 8   SAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELA 67
           +++I  + R     YEA  D L   Q Q    +V ++  +K      +E   +   +   
Sbjct: 185 NSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQ-LLKMKVESSQEANAEVMREMTK 243

Query: 68  KINTFYSEKLAEAQRRFAT----LQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERV 123
           K+ + Y EKL E QR+ +     L  E  S L A +E+        ++     +S EE+ 
Sbjct: 244 KLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEAN-------KKMQAAEISLEEKD 296

Query: 124 QHRNIKDLKLAFSE---FYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV 180
           Q     D  +   E     L L LL++   ++        +++ ++ E S     R+ H+
Sbjct: 297 QRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHL 356

Query: 181 EVAPFYTCKKINQLISETEAV 201
           +       KK+ Q++ E E++
Sbjct: 357 DDMVHCQQKKVKQMVEEIESL 377


>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
          Length = 466

 Score = 37.4 bits (85), Expect = 0.047
 Identities = 45/201 (22%), Positives = 84/201 (41%), Gaps = 15/201 (7%)

Query: 8   SAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELA 67
           +++I  + R     YEA  D L   Q Q    +V ++  +K      +E   +   +   
Sbjct: 185 NSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQ-LLKMKVESSQEANAEVMREMTK 243

Query: 68  KINTFYSEKLAEAQRRFAT----LQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERV 123
           K+ + Y EKL E QR+ +     L  E  S L A +E+        ++     +S EE+ 
Sbjct: 244 KLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEAN-------KKMQAAEISLEEKD 296

Query: 124 QHRNIKDLKLAFSE---FYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV 180
           Q     D  +   E     L L LL++   ++        +++ ++ E S     R+ H+
Sbjct: 297 QRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHL 356

Query: 181 EVAPFYTCKKINQLISETEAV 201
           +       KK+ Q++ E E++
Sbjct: 357 DDMVHCQQKKVKQMVEEIESL 377


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 36.6 bits (83), Expect = 0.081
 Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 7/157 (4%)

Query: 71  TFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHR-NIK 129
           T Y  KL   ++    + + +  S +A+ E      L    + +  L  +  ++HR NI+
Sbjct: 594 TNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIE 653

Query: 130 DLKLAFSEFYLSLI------LLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHVEVA 183
            LK      Y   I      + Q  + + F     I K++  ILE S+  D + + V   
Sbjct: 654 KLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSK 713

Query: 184 PFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRV 220
                 +IN+L  E E +   E E G  ++ ++ L++
Sbjct: 714 SEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQL 750


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 36.6 bits (83), Expect = 0.081
 Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 7/157 (4%)

Query: 71  TFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHR-NIK 129
           T Y  KL   ++    + + +  S +A+ E      L    + +  L  +  ++HR NI+
Sbjct: 594 TNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIE 653

Query: 130 DLKLAFSEFYLSLI------LLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHVEVA 183
            LK      Y   I      + Q  + + F     I K++  ILE S+  D + + V   
Sbjct: 654 KLKDNLGIHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSK 713

Query: 184 PFYTCKKINQLISETEAVVTNELEDGDRQKAMKRLRV 220
                 +IN+L  E E +   E E G  ++ ++ L++
Sbjct: 714 SEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQL 750


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 35.8 bits (81), Expect = 0.14
 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 6/62 (9%)

Query: 154 TGFRKILKKHDKILETSRGADWRVAHVEVAPFYTC---KKINQLISETEAVVTNELEDGD 210
           + F+  LKK    LE +  A W  + +   PF T    K I +LI+E +A VT E+EDG 
Sbjct: 263 SNFKDFLKK---CLEKNVDARWTTSQLLQHPFVTVDSNKPIRELIAEAKAEVTEEVEDGK 319

Query: 211 RQ 212
            +
Sbjct: 320 EE 321


>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
          Length = 438

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 46/207 (22%), Positives = 85/207 (41%), Gaps = 20/207 (9%)

Query: 8   SAHITPEWRKQYIQYEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELA 67
           +++I  + R     YEA  D L   Q Q    +V ++  +K      +E   +   +   
Sbjct: 185 NSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQ-LLKMKVESSQEANAEVMREMTK 243

Query: 68  KINTFYSEKLAEAQRRFA----TLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERV 123
           K+ + Y EKL E QR+ +     L  E  S L A +E+        ++     +S EE+ 
Sbjct: 244 KLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEA-------NKKMQAAEISLEEKD 296

Query: 124 QHRNIKDL---KLAFSEFYLSLILLQNYQNLNFTGFRKILKKHDKILETSRGADWRVAHV 180
           Q     D    ++      L L LL++   ++        +++ ++ E S     R+ H+
Sbjct: 297 QRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHL 356

Query: 181 EVAPFYTCKKINQLISETEAVVTNELE 207
           +       KK+ Q++ E      NEL+
Sbjct: 357 DDMVHCQQKKVKQMVEE-----NNELQ 378


>gi|61563742 hect domain and RLD 6 [Homo sapiens]
          Length = 1022

 Score = 35.4 bits (80), Expect = 0.18
 Identities = 22/102 (21%), Positives = 48/102 (47%), Gaps = 12/102 (11%)

Query: 46  TVKRYFAKFEEKFFQTCEKELAKI------------NTFYSEKLAEAQRRFATLQNELQS 93
           +VK  + +F+  F++ CEKE+ +             NT Y  K  E   ++     +   
Sbjct: 867 SVKAVYEEFQRGFYRVCEKEILRHFYPEELMTAIIGNTDYDWKQFEQNSKYEQGYQKSHP 926

Query: 94  SLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAF 135
           ++    ++    TL +++K +F L+  +R+  R I+ +++ F
Sbjct: 927 TIQLFWKAFHKLTLDEKKKFLFFLTGRDRLHARGIQKMEIVF 968


>gi|5174457 kinetochore associated 2 [Homo sapiens]
          Length = 642

 Score = 32.3 bits (72), Expect = 1.5
 Identities = 24/98 (24%), Positives = 51/98 (52%), Gaps = 7/98 (7%)

Query: 1   MKFAEHLSAHITPEWRKQYIQYEAFKDMLYSAQDQ---APSVEVTDEDTVKRYFAKFEE- 56
           +KF     A+   ++R Q   Y   K++L   +++   A + ++  EDT+++  A   E 
Sbjct: 439 IKFNPEAGANCLVKYRAQV--YVPLKELLNETEEEINKALNKKMGLEDTLEQLNAMITES 496

Query: 57  -KFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQS 93
            +  +T ++E+ K++  Y +K+ EA+       +EL+S
Sbjct: 497 KRSVRTLKEEVQKLDDLYQQKIKEAEEEDEKCASELES 534


>gi|27436948 lamin A/C isoform 3 [Homo sapiens]
          Length = 634

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 56  EKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVF 115
           E   QT ++EL      YSE+L E +RR  T   E+ +    + ES     L++ R    
Sbjct: 194 ENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELR---- 249

Query: 116 HLSHEERVQHRNIKDLKLAFS 136
              HE++V+    K+L+  +S
Sbjct: 250 -AQHEDQVEQYK-KELEKTYS 268


>gi|5031875 lamin A/C isoform 2 [Homo sapiens]
          Length = 572

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 56  EKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVF 115
           E   QT ++EL      YSE+L E +RR  T   E+ +    + ES     L++ R    
Sbjct: 194 ENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELR---- 249

Query: 116 HLSHEERVQHRNIKDLKLAFS 136
              HE++V+    K+L+  +S
Sbjct: 250 -AQHEDQVEQYK-KELEKTYS 268


>gi|27436946 lamin A/C isoform 1 precursor [Homo sapiens]
          Length = 664

 Score = 32.0 bits (71), Expect = 2.0
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 6/81 (7%)

Query: 56  EKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVF 115
           E   QT ++EL      YSE+L E +RR  T   E+ +    + ES     L++ R    
Sbjct: 194 ENRLQTMKEELDFQKNIYSEELRETKRRHETRLVEIDNGKQREFESRLADALQELR---- 249

Query: 116 HLSHEERVQHRNIKDLKLAFS 136
              HE++V+    K+L+  +S
Sbjct: 250 -AQHEDQVEQYK-KELEKTYS 268


>gi|148271104 patched domain containing 1 [Homo sapiens]
          Length = 888

 Score = 31.6 bits (70), Expect = 2.6
 Identities = 26/92 (28%), Positives = 38/92 (41%), Gaps = 8/92 (8%)

Query: 379 FRVFTAPFHKVGFADFWLADQLNSLSVILMDLEYMICFYSLELKWDESKGLLPNNSEESG 438
           F +  +PF  +  A  +     NS   I  +  Y++ FY   L +    G + NN + S 
Sbjct: 386 FGIGASPFTNIEAARIFCC---NSCIAIFFNYLYVLSFYGSSLVFT---GYIENNYQHSI 439

Query: 439 ICHKYTYGVRAIVQCIPAWLRFIQCLRRYRDT 470
            C K        +Q  PAW RF+   R   DT
Sbjct: 440 FCRKVPKP--EALQEKPAWYRFLLTARFSEDT 469


>gi|14150134 coiled-coil-helix-coiled-coil-helix domain containing 6
           [Homo sapiens]
          Length = 235

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 23/99 (23%), Positives = 44/99 (44%), Gaps = 7/99 (7%)

Query: 44  EDTVKRY---FAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKE 100
           ++ VKRY    A  ++K FQ  ++E           L   +    ++ +E Q S+   +E
Sbjct: 84  KEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGE---GSISHEEQKSVRLARE 140

Query: 101 STGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFY 139
                    RR+  F+    ER++ +N +  KL+  +F+
Sbjct: 141 LES-REAELRRRDTFYKEQLERIERKNAEMYKLSSEQFH 178


>gi|75677351 suppressor of defective silencing 3 [Homo sapiens]
          Length = 328

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 12/123 (9%)

Query: 22  YEAFKDMLYSAQDQAPSVE--VTDEDTV---KRYFAKFEEKFFQTCEKELAKINTFYSEK 76
           Y    + L SA+D   S     +DEDT    +   AK +E+ +   ++++      Y +K
Sbjct: 23  YPEEDEELESAEDDERSCRGRESDEDTEDASETDLAKHDEEDYVEMKEQM------YQDK 76

Query: 77  LAEAQRRFATLQN-ELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAF 135
           LA  +R+   LQ   LQ      K+       R R   +F     E+V+   IK+ K A 
Sbjct: 77  LASLKRQLQQLQEGTLQEYQKRMKKLDQQYKERIRNAELFLQLETEQVERNYIKEKKAAV 136

Query: 136 SEF 138
            EF
Sbjct: 137 KEF 139


>gi|14249254 EF-hand calcium binding domain 4B isoform c [Homo
           sapiens]
          Length = 395

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 24/113 (21%), Positives = 48/113 (42%), Gaps = 5/113 (4%)

Query: 22  YEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQ 81
           +E F   + S   +A   +   E  +KR  A ++E+     E+   +I +   + L +  
Sbjct: 197 FEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDT 256

Query: 82  RRFATLQNELQSSLDAQKESTGVTTLRQRR-----KPVFHLSHEERVQHRNIK 129
            RF     EL+  L  +++     T +Q+R       + H  HE + ++  +K
Sbjct: 257 ERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHETKAENTKLK 309


>gi|222418793 EF-hand calcium binding domain 4B isoform b [Homo
           sapiens]
          Length = 462

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 24/113 (21%), Positives = 48/113 (42%), Gaps = 5/113 (4%)

Query: 22  YEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQ 81
           +E F   + S   +A   +   E  +KR  A ++E+     E+   +I +   + L +  
Sbjct: 197 FEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDT 256

Query: 82  RRFATLQNELQSSLDAQKESTGVTTLRQRR-----KPVFHLSHEERVQHRNIK 129
            RF     EL+  L  +++     T +Q+R       + H  HE + ++  +K
Sbjct: 257 ERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHETKAENTKLK 309


>gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo
           sapiens]
          Length = 731

 Score = 30.8 bits (68), Expect = 4.4
 Identities = 24/113 (21%), Positives = 48/113 (42%), Gaps = 5/113 (4%)

Query: 22  YEAFKDMLYSAQDQAPSVEVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQ 81
           +E F   + S   +A   +   E  +KR  A ++E+     E+   +I +   + L +  
Sbjct: 197 FEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDT 256

Query: 82  RRFATLQNELQSSLDAQKESTGVTTLRQRR-----KPVFHLSHEERVQHRNIK 129
            RF     EL+  L  +++     T +Q+R       + H  HE + ++  +K
Sbjct: 257 ERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHETKAENTKLK 309


>gi|50083279 centrosome protein 4 [Homo sapiens]
          Length = 1140

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 4/106 (3%)

Query: 40  EVTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQ---RRFATLQNELQSSLD 96
           E+T+ D + +   + +E+  +T +KEL +       KL+E Q      A LQ EL     
Sbjct: 318 ELTEIDQLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEETMAKLQLELNLCQK 377

Query: 97  AQKESTGVTTLRQRRKPVFHLSHEERVQHRNIKDLKLAFSEFYLSL 142
            ++  +    ++   + V H   +E+ Q  + K    A +E  L+L
Sbjct: 378 EKERLSDELLVKSDLETVVHQLEQEK-QRLSKKVESFAVTERQLTL 422


>gi|66773038 cell division cycle 37 homolog (S. cerevisiae)-like 1
           [Homo sapiens]
          Length = 337

 Score = 30.4 bits (67), Expect = 5.8
 Identities = 19/52 (36%), Positives = 27/52 (51%), Gaps = 2/52 (3%)

Query: 63  EKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQ--KESTGVTTLRQRRK 112
           +KE  K +      LAEAQ++  +L      SLD +  K  T V+ LRQR +
Sbjct: 57  QKEFVKSSVACKWNLAEAQQKLGSLALHNSESLDQEHAKAQTAVSELRQREE 108


>gi|4507011 glucose transporter 4 [Homo sapiens]
          Length = 509

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 8/65 (12%)

Query: 300 VLIFELNPRSNLSHQHLFEIAGFLGILWCLSLLACFFAPISVIP--TYVYPLALYGFMVF 357
           VL+ E   R  L   HL  +AG  G   C  L+      +  +P  +YV  +A++GF+ F
Sbjct: 341 VLLVERAGRRTL---HLLGLAGMCG---CAILMTVALLLLERVPAMSYVSIVAIFGFVAF 394

Query: 358 FLINP 362
           F I P
Sbjct: 395 FEIGP 399


>gi|122937514 unc-13 homolog C [Homo sapiens]
          Length = 2214

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 13/72 (18%)

Query: 64  KELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKESTGVTTLRQRRKPVFHLSHEERV 123
           +EL+ I + YSE L           NEL+SS + Q +ST    +R+ RK    L+  E  
Sbjct: 118 QELSSIESSYSESL-----------NELRSSTENQAQSTHTMPVRRNRKSSSSLAPSEGS 166

Query: 124 Q--HRNIKDLKL 133
               R +  LKL
Sbjct: 167 SDGERTLHGLKL 178


>gi|210147514 ring finger protein 187 [Homo sapiens]
          Length = 126

 Score = 30.0 bits (66), Expect = 7.6
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 5/69 (7%)

Query: 41  VTDEDTVKRYFAKFEEKFFQTCEKELAKINTFYSEKLAEAQRRFATLQNELQSSLDAQKE 100
           +TD   ++ +F + EE F Q  EKE         ++LA+   RF +L   + S L+ +  
Sbjct: 63  LTDYKKLRAFFVEEEEHFLQEAEKE----EGLPEDELADPTERFRSLLQAV-SELEKKHR 117

Query: 101 STGVTTLRQ 109
           + G++ L Q
Sbjct: 118 NLGLSMLLQ 126


>gi|166795299 solute carrier family 2 (facilitated glucose
           transporter), member 1 [Homo sapiens]
          Length = 492

 Score = 29.6 bits (65), Expect = 9.9
 Identities = 16/50 (32%), Positives = 27/50 (54%), Gaps = 5/50 (10%)

Query: 315 HLFEIAGFLGILWCLSLLACFFAPISVIP--TYVYPLALYGFMVFFLINP 362
           HL  +AG  G   C  L+    A +  +P  +Y+  +A++GF+ FF + P
Sbjct: 337 HLIGLAGMAG---CAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGP 383


>gi|25121987 non-SMC condensin I complex, subunit H [Homo sapiens]
          Length = 741

 Score = 29.6 bits (65), Expect = 9.9
 Identities = 16/54 (29%), Positives = 23/54 (42%)

Query: 632 APLNADDQTLLEQMMDQDDGVRNRQKNRSWKYNQSISLRRPRLASQSKARDTKV 685
           APLN     +LE     DD     Q+ RS  ++   S   PRL +   +R   +
Sbjct: 42  APLNIPGTPVLEDFPQNDDEKERLQRRRSRVFDLQFSTDSPRLLASPSSRSIDI 95


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,513,457
Number of Sequences: 37866
Number of extensions: 1029667
Number of successful extensions: 3483
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 3460
Number of HSP's gapped (non-prelim): 45
length of query: 696
length of database: 18,247,518
effective HSP length: 109
effective length of query: 587
effective length of database: 14,120,124
effective search space: 8288512788
effective search space used: 8288512788
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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