Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 19923090
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19923090 RUN domain containing 3B isoform a [Homo sapiens]
(473 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|19923090 RUN domain containing 3B isoform a [Homo sapiens] 939 0.0
gi|197304744 RUN domain containing 3B isoform b [Homo sapiens] 892 0.0
gi|197304746 RUN domain containing 3B isoform c [Homo sapiens] 768 0.0
gi|221307578 RUN domain containing 3A isoform 1 [Homo sapiens] 440 e-123
gi|5730015 RUN domain containing 3A isoform 2 [Homo sapiens] 395 e-110
gi|221307580 RUN domain containing 3A isoform 3 [Homo sapiens] 394 e-109
gi|195220720 RUN and FYVE domain containing 3 isoform 3 [Homo sa... 112 6e-25
gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo sa... 108 1e-23
gi|7662352 RUN and FYVE domain containing 3 isoform 2 [Homo sapi... 107 2e-23
gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo sap... 107 2e-23
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 103 3e-22
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 96 7e-20
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 96 7e-20
gi|109240552 RUN and FYVE domain-containing 2 isoform b [Homo sa... 82 1e-15
gi|116292170 RUN domain containing 2A [Homo sapiens] 64 3e-10
gi|122891862 DENN/MADD domain containing 5B [Homo sapiens] 47 5e-05
gi|44889475 RAB6 interacting protein 1 [Homo sapiens] 45 2e-04
gi|40538728 pleckstrin homology domain containing, family M (wit... 42 0.001
gi|221139728 pleckstrin homology domain containing, family M (wi... 41 0.002
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 38 0.023
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 38 0.023
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do... 37 0.039
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 37 0.051
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 37 0.051
gi|16306548 seryl-tRNA synthetase [Homo sapiens] 36 0.087
gi|31982906 cingulin-like 1 [Homo sapiens] 35 0.11
gi|5032281 dystrophin Dp427c isoform [Homo sapiens] 35 0.19
gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens] 35 0.19
gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens] 35 0.19
gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens] 35 0.19
>gi|19923090 RUN domain containing 3B isoform a [Homo sapiens]
Length = 473
Score = 939 bits (2426), Expect = 0.0
Identities = 473/473 (100%), Positives = 473/473 (100%)
Query: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS
Sbjct: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
Query: 61 PEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRK 120
PEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRK
Sbjct: 61 PEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRK 120
Query: 121 VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL 180
VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL
Sbjct: 121 VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL 180
Query: 181 GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT 240
GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT
Sbjct: 181 GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT 240
Query: 241 LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES 300
LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES
Sbjct: 241 LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES 300
Query: 301 VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPS 360
VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPS
Sbjct: 301 VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPS 360
Query: 361 PGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL 420
PGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL
Sbjct: 361 PGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL 420
Query: 421 NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 473
NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS
Sbjct: 421 NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 473
>gi|197304744 RUN domain containing 3B isoform b [Homo sapiens]
Length = 456
Score = 892 bits (2306), Expect = 0.0
Identities = 456/473 (96%), Positives = 456/473 (96%), Gaps = 17/473 (3%)
Query: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS
Sbjct: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
Query: 61 PEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRK 120
PEFNNFAAILEQILSHRLK GQVTWFGYESPRSFWDYIRVACRK
Sbjct: 61 PEFNNFAAILEQILSHRLK-----------------GQVTWFGYESPRSFWDYIRVACRK 103
Query: 121 VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL 180
VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL
Sbjct: 104 VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL 163
Query: 181 GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT 240
GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT
Sbjct: 164 GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT 223
Query: 241 LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES 300
LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES
Sbjct: 224 LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES 283
Query: 301 VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPS 360
VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPS
Sbjct: 284 VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPS 343
Query: 361 PGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL 420
PGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL
Sbjct: 344 PGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL 403
Query: 421 NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 473
NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS
Sbjct: 404 NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 456
>gi|197304746 RUN domain containing 3B isoform c [Homo sapiens]
Length = 407
Score = 768 bits (1983), Expect = 0.0
Identities = 407/473 (86%), Positives = 407/473 (86%), Gaps = 66/473 (13%)
Query: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS
Sbjct: 1 MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSS 60
Query: 61 PEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRK 120
PEFNNFAAILEQILSHRLK GQVTWFGYESPRSFWDYIRVACRK
Sbjct: 61 PEFNNFAAILEQILSHRLK-----------------GQVTWFGYESPRSFWDYIRVACRK 103
Query: 121 VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL 180
VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL
Sbjct: 104 VSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVL 163
Query: 181 GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT 240
GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT
Sbjct: 164 GEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRT 223
Query: 241 LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES 300
LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES
Sbjct: 224 LGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSES 283
Query: 301 VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPS 360
VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQL
Sbjct: 284 VSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQL------------------------ 319
Query: 361 PGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL 420
KSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL
Sbjct: 320 -------------------------KSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTL 354
Query: 421 NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 473
NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS
Sbjct: 355 NVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 407
>gi|221307578 RUN domain containing 3A isoform 1 [Homo sapiens]
Length = 446
Score = 440 bits (1132), Expect = e-123
Identities = 244/460 (53%), Positives = 318/460 (69%), Gaps = 30/460 (6%)
Query: 18 GGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHR 77
G K S+RN AVER+NLITVCRFSVKTL+++ E IDDSS EF NFAAILEQILSHR
Sbjct: 13 GLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHR 72
Query: 78 LKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSS 137
K + + G V+WF + R FWDYIR+AC KV NC+ SIENMEN+S+
Sbjct: 73 FKACAPA------------GPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST 120
Query: 138 SRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAI 197
+RAKGRAWIRVALMEK +SEYI+TALRD +TTRRFY+ GAI+L +EA +L GML+GL+AI
Sbjct: 121 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI 180
Query: 198 DFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPP 257
DFSFCLKGE LDG P VIDYTPYLK+ QS D + +DEEE + SS SE ++PE+ P
Sbjct: 181 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYL-TDEEERHSAESSTSEDNSPEHPYLP 239
Query: 258 FLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLA 317
+ DE+SW++K +++QK+++ QKGYLEEL+RLRE+QL + ++N+ L ++E++
Sbjct: 240 LVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQ 299
Query: 318 HKLEKEQLEYIIVELQDQLTVLKNND----LRSRQELTAHLTNQWPSPGALDVNAVALDT 373
++ EK +LE +I+ELQ+QLT L +D + +ELT L NQWPS G L+ A ++
Sbjct: 300 NQREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNS 359
Query: 374 LLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSL 433
LYR+H S+ S + LSAE SLS S + G+G +D GK+ TPS+
Sbjct: 360 KLYRRH-------SFMSTEPLSAEASLSSDS-----QRLGEGTRDEEPWGPIGKDPTPSM 407
Query: 434 LGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS 473
LGLCGSL S+ S KSL S KSN+ L S + E SP L+PS
Sbjct: 408 LGLCGSLASIPSCKSLASFKSNECLVSDSPE-GSPALSPS 446
>gi|5730015 RUN domain containing 3A isoform 2 [Homo sapiens]
Length = 405
Score = 395 bits (1016), Expect = e-110
Identities = 215/405 (53%), Positives = 283/405 (69%), Gaps = 29/405 (7%)
Query: 18 GGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHR 77
G K S+RN AVER+NLITVCRFSVKTL+++ E IDDSS EF NFAAILEQILSHR
Sbjct: 13 GLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHR 72
Query: 78 LKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSS 137
K + + G V+WF + R FWDYIR+AC KV NC+ SIENMEN+S+
Sbjct: 73 FKACAPA------------GPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST 120
Query: 138 SRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAI 197
+RAKGRAWIRVALMEK +SEYI+TALRD +TTRRFY+ GAI+L +EA +L GML+GL+AI
Sbjct: 121 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI 180
Query: 198 DFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPP 257
DFSFCLKGE LDG P VIDYTPYLK+ QS D + +DEEE + SS SE ++PE+ P
Sbjct: 181 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYL-TDEEERHSAESSTSEDNSPEHPYLP 239
Query: 258 FLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLA 317
+ DE+SW++K +++QK+++ QKGYLEEL+RLRE+QL + ++N+ L ++E++
Sbjct: 240 LVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQ 299
Query: 318 HKLEKEQLEYIIVELQDQLTVLKNND----LRSRQELTAHLTNQWPSPGALDVNAVALDT 373
++ EK +LE +I+ELQ+QLT L +D + +ELT L NQWPS G L+ A ++
Sbjct: 300 NQREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNS 359
Query: 374 LLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQD 418
LYR+H S+ S + LSAE SLS S + G+G +D
Sbjct: 360 KLYRRH-------SFMSTEPLSAEASLSSDS-----QRLGEGTRD 392
>gi|221307580 RUN domain containing 3A isoform 3 [Homo sapiens]
Length = 400
Score = 394 bits (1012), Expect = e-109
Identities = 215/405 (53%), Positives = 281/405 (69%), Gaps = 34/405 (8%)
Query: 18 GGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHR 77
G K S+RN AVER+NLITVCRFSVKTL+++ E IDDSS EF NFAAILEQILSHR
Sbjct: 13 GLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHR 72
Query: 78 LKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSS 137
K G V+WF + R FWDYIR+AC KV NC+ SIENMEN+S+
Sbjct: 73 FK-----------------GPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENIST 115
Query: 138 SRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAI 197
+RAKGRAWIRVALMEK +SEYI+TALRD +TTRRFY+ GAI+L +EA +L GML+GL+AI
Sbjct: 116 ARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAI 175
Query: 198 DFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPP 257
DFSFCLKGE LDG P VIDYTPYLK+ QS D + +DEEE + SS SE ++PE+ P
Sbjct: 176 DFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYL-TDEEERHSAESSTSEDNSPEHPYLP 234
Query: 258 FLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLA 317
+ DE+SW++K +++QK+++ QKGYLEEL+RLRE+QL + ++N+ L ++E++
Sbjct: 235 LVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQ 294
Query: 318 HKLEKEQLEYIIVELQDQLTVLKNND----LRSRQELTAHLTNQWPSPGALDVNAVALDT 373
++ EK +LE +I+ELQ+QLT L +D + +ELT L NQWPS G L+ A ++
Sbjct: 295 NQREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNS 354
Query: 374 LLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQD 418
LYR+H S+ S + LSAE SLS S + G+G +D
Sbjct: 355 KLYRRH-------SFMSTEPLSAEASLSSDS-----QRLGEGTRD 387
>gi|195220720 RUN and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 112 bits (281), Expect = 6e-25
Identities = 73/225 (32%), Positives = 113/225 (50%), Gaps = 24/225 (10%)
Query: 14 GGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCF--ETIDDSSPEFNNFAAILE 71
GGG G K A ER NL+ + + S+K LI+ + T+D F ++E
Sbjct: 110 GGGSSGSGKHHPNYLMANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVME 169
Query: 72 QILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQ--NCICSI 129
L H LK + T+ G +SFW + + + V + S+
Sbjct: 170 HCLKHGLK-----------------AKKTFLGQN--KSFWGPLELVEKLVPEAAEITASV 210
Query: 130 ENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAG 189
+++ + + +GRAW+R+ALM+K LSEY+ + + FYE A+++ EE ++AG
Sbjct: 211 KDLPGLKTPVGRGRAWLRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAG 270
Query: 190 MLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSD 234
+L+GLN ID +FC+KGE LD S VID++ YLK SS D
Sbjct: 271 LLVGLNVIDANFCMKGEDLD-SQVGVIDFSMYLKDGNSSKGTEGD 314
>gi|109240556 RUN and FYVE domain-containing 2 isoform a [Homo
sapiens]
Length = 641
Score = 108 bits (270), Expect = 1e-23
Identities = 110/409 (26%), Positives = 187/409 (45%), Gaps = 81/409 (19%)
Query: 2 ASRSLGGLSGIRGGGGGG-GKKSLSARN-AAVERRNLITVCRFSVKTLIDR--SCFETID 57
AS+ L + GG G ++SL+ ++ AVER NL+ + + S+K LI+ S T+D
Sbjct: 13 ASQVLAWVPDAEGGRRGMLTRRSLATKDPTAVERANLLNMAKLSIKGLIESALSFGRTLD 72
Query: 58 DSSPEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVA 117
P F ++E L H LK + ++ Y ++ W + +
Sbjct: 73 SDYPPLQQFFVVMEHCLKHGLKV-----------------RKSFLSYN--KTIWGPLELV 113
Query: 118 CRKV--SQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYED 175
+ ++ S+ ++ + + + RAW+R+ALM+K +++Y+ + FYE
Sbjct: 114 EKLYPEAEEIGASVRDLPGLKTPLGRARAWLRLALMQKKMADYLRCLIIQRDLLSEFYEY 173
Query: 176 GAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDE 235
A+++ EE ++ G+L+GLN ID + C+KGE LD S VID++ YLK
Sbjct: 174 HALMMEEEGAVIVGLLVGLNVIDANLCVKGEDLD-SQVGVIDFSMYLK------------ 220
Query: 236 EELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLREN 295
E++G NK + V + L+QK Y+EEL R
Sbjct: 221 --------------NEEDIG-----------NKERNV--QIAAILDQKNYVEELNR---- 249
Query: 296 QLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLT 355
QL+ +VS + +E S+ E + I++LQ++ N+ LRS +L T
Sbjct: 250 QLNSTVSSLHSRVDSLEKSNTKLIEELAIAKNNIIKLQEE-----NHQLRSENKLILMKT 304
Query: 356 NQWPSPGALDVNAVALDTLLYR-KHNKQWYEKSY-QSLDQLSAEVSLSQ 402
Q L+V V ++T L KH++Q ++ Y ++ QL E L Q
Sbjct: 305 QQ-----HLEVTKVDVETELQTYKHSRQGLDEMYNEARRQLRDESQLRQ 348
>gi|7662352 RUN and FYVE domain containing 3 isoform 2 [Homo
sapiens]
Length = 469
Score = 107 bits (267), Expect = 2e-23
Identities = 68/209 (32%), Positives = 108/209 (51%), Gaps = 24/209 (11%)
Query: 30 AVERRNLITVCRFSVKTLIDRSCF--ETIDDSSPEFNNFAAILEQILSHRLKEISQSCRW 87
A ER NL+ + + S+K LI+ + T+D F ++E L H LK
Sbjct: 66 ANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK-------- 117
Query: 88 LAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQ--NCICSIENMENVSSSRAKGRAW 145
+ T+ G +SFW + + + V + S++++ + + +GRAW
Sbjct: 118 ---------AKKTFLGQN--KSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAW 166
Query: 146 IRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKG 205
+R+ALM+K LSEY+ + + FYE A+++ EE ++AG+L+GLN ID +FC+KG
Sbjct: 167 LRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKG 226
Query: 206 EGLDGSFPAVIDYTPYLKYIQSSDSISSD 234
E LD S VID++ YLK SS D
Sbjct: 227 EDLD-SQVGVIDFSMYLKDGNSSKGTEGD 254
>gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 620
Score = 107 bits (267), Expect = 2e-23
Identities = 68/209 (32%), Positives = 108/209 (51%), Gaps = 24/209 (11%)
Query: 30 AVERRNLITVCRFSVKTLIDRSCF--ETIDDSSPEFNNFAAILEQILSHRLKEISQSCRW 87
A ER NL+ + + S+K LI+ + T+D F ++E L H LK
Sbjct: 66 ANERMNLMNMAKLSIKGLIESALNLGRTLDSDYAPLQQFFVVMEHCLKHGLK-------- 117
Query: 88 LAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQ--NCICSIENMENVSSSRAKGRAW 145
+ T+ G +SFW + + + V + S++++ + + +GRAW
Sbjct: 118 ---------AKKTFLGQN--KSFWGPLELVEKLVPEAAEITASVKDLPGLKTPVGRGRAW 166
Query: 146 IRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKG 205
+R+ALM+K LSEY+ + + FYE A+++ EE ++AG+L+GLN ID +FC+KG
Sbjct: 167 LRLALMQKKLSEYMKALINKKELLSEFYEPNALMMEEEGAIIAGLLVGLNVIDANFCMKG 226
Query: 206 EGLDGSFPAVIDYTPYLKYIQSSDSISSD 234
E LD S VID++ YLK SS D
Sbjct: 227 EDLD-SQVGVIDFSMYLKDGNSSKGTEGD 254
Score = 30.0 bits (66), Expect = 4.8
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 8/97 (8%)
Query: 274 QKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDS----DLAHKLEKEQLEYII 329
Q L ++QK L L + NQ++ ++ Q + L++ E S +L ++L K+ I
Sbjct: 413 QSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSAELDNRLFKQDFGDKI 472
Query: 330 VELQ---DQLTVLKNN-DLRSRQELTAHLTNQWPSPG 362
LQ ++LT +N +L +QE L N PG
Sbjct: 473 NSLQLEVEELTRQRNQLELELKQEKERRLQNDRSIPG 509
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 103 bits (258), Expect = 3e-22
Identities = 103/405 (25%), Positives = 172/405 (42%), Gaps = 93/405 (22%)
Query: 2 ASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDR--SCFETIDDS 59
A R+ GL G G G G ++ S ER NL+ + + S+K L+ S ++D
Sbjct: 84 ALRAAAGLGG--GDSGDGTARAASKCQMMEERANLMHMMKLSIKVLLQSALSLGRSLDAD 141
Query: 60 SPEFNNFAAILEQILSHRLKE----ISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIR 115
F ++E L H LK I Q+ + L++ +
Sbjct: 142 HAPLQQFFVVMEHCLKHGLKVKKSFIGQNKSFFGPLEL--------------------VE 181
Query: 116 VACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYED 175
C + S + S+ N+ + ++ +GRAW+ +ALM+K L++Y+ + + FYE
Sbjct: 182 KLCPEAS-DIATSVRNLPELKTAVGRGRAWLYLALMQKKLADYLKVLIDNKHLLSEFYEP 240
Query: 176 GAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDE 235
A+++ EE ++ G+L+GLN +D + CLKGE LD S VID++ YLK +Q D
Sbjct: 241 EALMMEEEGMVIVGLLVGLNVLDANLCLKGEDLD-SQVGVIDFSLYLKDVQDLD------ 293
Query: 236 EELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLREN 295
G E +V L+QK Y+EEL R
Sbjct: 294 --------GGKEHERITDV-------------------------LDQKNYVEELNR---- 316
Query: 296 QLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLK--NNDLRSRQELTAH 353
LS +V + + +E ++ + E I LQ++ L+ N +R R E +
Sbjct: 317 HLSCTVGDLQTKIDGLEKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVE 376
Query: 354 LTNQWPSPGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEV 398
+T Q DT K + Y+++ Q LD++ ++V
Sbjct: 377 ITKQ--------------DT----KVELETYKQTRQGLDEMYSDV 403
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 95.9 bits (237), Expect = 7e-20
Identities = 94/375 (25%), Positives = 160/375 (42%), Gaps = 91/375 (24%)
Query: 32 ERRNLITVCRFSVKTLIDR--SCFETIDDSSPEFNNFAAILEQILSHRLKE----ISQSC 85
ER NL+ + + S+K L+ S ++D F ++E L H LK I Q+
Sbjct: 4 ERANLMHMMKLSIKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQNK 63
Query: 86 RWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAW 145
+ L++ + C + S + S+ N+ + ++ +GRAW
Sbjct: 64 SFFGPLEL--------------------VEKLCPEAS-DIATSVRNLPELKTAVGRGRAW 102
Query: 146 IRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKG 205
+ +ALM+K L++Y+ + + FYE A+++ EE ++ G+L+GLN +D + CLKG
Sbjct: 103 LYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDANLCLKG 162
Query: 206 EGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSW 265
E LD S VID++ YLK +Q D G E +V
Sbjct: 163 EDLD-SQVGVIDFSLYLKDVQDLD--------------GGKEHERITDV----------- 196
Query: 266 FNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQL 325
L+QK Y+EEL R LS +V + + +E ++ + E
Sbjct: 197 --------------LDQKNYVEELNR----HLSCTVGDLQTKIDGLEKTNSKLQEELSAA 238
Query: 326 EYIIVELQDQLTVLK--NNDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYRKHNKQW 383
I LQ++ L+ N +R R E + +T Q DT K +
Sbjct: 239 TDRICSLQEEQQQLREQNELIRERSEKSVEITKQ--------------DT----KVELET 280
Query: 384 YEKSYQSLDQLSAEV 398
Y+++ Q LD++ ++V
Sbjct: 281 YKQTRQGLDEMYSDV 295
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 95.9 bits (237), Expect = 7e-20
Identities = 94/375 (25%), Positives = 160/375 (42%), Gaps = 91/375 (24%)
Query: 32 ERRNLITVCRFSVKTLIDR--SCFETIDDSSPEFNNFAAILEQILSHRLKE----ISQSC 85
ER NL+ + + S+K L+ S ++D F ++E L H LK I Q+
Sbjct: 4 ERANLMHMMKLSIKVLLQSALSLGRSLDADHAPLQQFFVVMEHCLKHGLKVKKSFIGQNK 63
Query: 86 RWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAW 145
+ L++ + C + S + S+ N+ + ++ +GRAW
Sbjct: 64 SFFGPLEL--------------------VEKLCPEAS-DIATSVRNLPELKTAVGRGRAW 102
Query: 146 IRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKG 205
+ +ALM+K L++Y+ + + FYE A+++ EE ++ G+L+GLN +D + CLKG
Sbjct: 103 LYLALMQKKLADYLKVLIDNKHLLSEFYEPEALMMEEEGMVIVGLLVGLNVLDANLCLKG 162
Query: 206 EGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSW 265
E LD S VID++ YLK +Q D G E +V
Sbjct: 163 EDLD-SQVGVIDFSLYLKDVQDLD--------------GGKEHERITDV----------- 196
Query: 266 FNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQL 325
L+QK Y+EEL R LS +V + + +E ++ + E
Sbjct: 197 --------------LDQKNYVEELNR----HLSCTVGDLQTKIDGLEKTNSKLQEELSAA 238
Query: 326 EYIIVELQDQLTVLK--NNDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYRKHNKQW 383
I LQ++ L+ N +R R E + +T Q DT K +
Sbjct: 239 TDRICSLQEEQQQLREQNELIRERSEKSVEITKQ--------------DT----KVELET 280
Query: 384 YEKSYQSLDQLSAEV 398
Y+++ Q LD++ ++V
Sbjct: 281 YKQTRQGLDEMYSDV 295
>gi|109240552 RUN and FYVE domain-containing 2 isoform b [Homo
sapiens]
Length = 403
Score = 81.6 bits (200), Expect = 1e-15
Identities = 101/379 (26%), Positives = 154/379 (40%), Gaps = 113/379 (29%)
Query: 30 AVERRNLITVCRFSVKTLIDR--SCFETIDDSSPEFNNFAAILEQILSHRLKEISQSCRW 87
AVER NL+ + + S+K LI+ S T+D P F ++E L H LK
Sbjct: 8 AVERANLLNMAKLSIKGLIESALSFGRTLDSDYPPLQQFFVVMEHCLKHGLKV------- 60
Query: 88 LAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIR 147
+SF Y + W
Sbjct: 61 -------------------RKSFLSYNKTI---------------------------WGP 74
Query: 148 VALMEKHL--SEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKG 205
+ L+EK +E I ++RD FYE A+++ EE ++ G+L+GLN ID + C+KG
Sbjct: 75 LELVEKLYPEAEEIGASVRDLPGLNEFYEYHALMMEEEGAVIVGLLVGLNVIDANLCVKG 134
Query: 206 EGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSW 265
E LD S VID++ YLK E++G
Sbjct: 135 EDLD-SQVGVIDFSMYLK--------------------------NEEDIG---------- 157
Query: 266 FNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQL 325
NK + V + L+QK Y+EEL R QL+ +VS + +E S+ E
Sbjct: 158 -NKERNV--QIAAILDQKNYVEELNR----QLNSTVSSLHSRVDSLEKSNTKLIEELAIA 210
Query: 326 EYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYR-KHNKQWY 384
+ I++LQ++ N+ LRS +L T Q L+V V ++T L KH++Q
Sbjct: 211 KNNIIKLQEE-----NHQLRSENKLILMKTQQ-----HLEVTKVDVETELQTYKHSRQGL 260
Query: 385 EKSY-QSLDQLSAEVSLSQ 402
++ Y ++ QL E L Q
Sbjct: 261 DEMYNEARRQLRDESQLRQ 279
>gi|116292170 RUN domain containing 2A [Homo sapiens]
Length = 375
Score = 63.9 bits (154), Expect = 3e-10
Identities = 72/238 (30%), Positives = 104/238 (43%), Gaps = 27/238 (11%)
Query: 54 ETIDDSSPEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGY--ESPRSFW 111
E DS A E +L H LK R LA ++ Q F E+ FW
Sbjct: 33 EIASDSDSRVTCLCAQFEAVLQHGLKR----SRGLALTAAAIK-QAAGFASKTETEPVFW 87
Query: 112 DYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRR 171
Y++ K S+ + ++S +GRAW+R AL E L Y+ L D
Sbjct: 88 YYVKEVLNKHELQRFYSLRH---IASDVGRGRAWLRCALNEHSLERYLHMLLADRCRLST 144
Query: 172 FYEDGAIVLGEE-ANMLAGMLLGLNAIDFSFCLKGEGLDGS---FPAVID--------YT 219
FYED + V+ EE ++ML M GLN+I F+ + + L+G P V D T
Sbjct: 145 FYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVT 204
Query: 220 PYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPF-LMDEN-SWFNKCKRVKQK 275
LK +S+ +SS E+ T S+ S PE P ++ N S KCK+ ++K
Sbjct: 205 SLLK--ESTQGVSSLFREI-TASSAVSILIKPEQETDPLPVVSRNVSADAKCKKERKK 259
>gi|122891862 DENN/MADD domain containing 5B [Homo sapiens]
Length = 1274
Score = 46.6 bits (109), Expect = 5e-05
Identities = 26/75 (34%), Positives = 43/75 (57%), Gaps = 2/75 (2%)
Query: 129 IENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIV-LGEEANML 187
I+NM + + + RAWIR++L +K LS+++ L + T++ Y+ A + EE
Sbjct: 853 IQNMSEIKTDVGRARAWIRLSLEKKLLSQHLKQLLSNQPLTKKLYKRYAFLRCEEEREQF 912
Query: 188 AGMLLGLNAIDFSFC 202
LL LNA+D+ FC
Sbjct: 913 LYHLLSLNAVDY-FC 926
>gi|44889475 RAB6 interacting protein 1 [Homo sapiens]
Length = 1287
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 2/75 (2%)
Query: 129 IENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIV-LGEEANML 187
I+N+ + + K RAW+R+++ +K LS ++ L D + T++ Y+ A + +E
Sbjct: 871 IQNIGEIKTDVGKARAWVRLSMEKKLLSRHLKQLLSDHELTKKLYKRYAFLRCDDEKEQF 930
Query: 188 AGMLLGLNAIDFSFC 202
LL NA+D+ FC
Sbjct: 931 LYHLLSFNAVDY-FC 944
>gi|40538728 pleckstrin homology domain containing, family M (with
RUN domain) member 1 [Homo sapiens]
Length = 1056
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/178 (20%), Positives = 73/178 (41%), Gaps = 17/178 (9%)
Query: 31 VERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKEISQSCRWLAH 90
V ++ L+ + K + T +D + N + LE + H L H
Sbjct: 17 VIKKKLVGSVKALQKQYVSLDTVVTSEDG--DANTMCSALEAVFIHGLHA--------KH 66
Query: 91 LQIPLQGQVTWFGYESPRS---FWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIR 147
++ G+ ++ P FW ++ K + I +E++ V++ + RAW+R
Sbjct: 67 IRAEAGGKRKKSAHQKPLPQPVFWPLLKAVTHK---HIISELEHLTFVNTDVGRCRAWLR 123
Query: 148 VALMEKHLSEYISTALRDFKTTRRFYEDGAIVL-GEEANMLAGMLLGLNAIDFSFCLK 204
+AL + + Y+ L++ +Y+ A++ EE L L GL ++ F K
Sbjct: 124 LALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYK 181
>gi|221139728 pleckstrin homology domain containing, family M (with
RUN domain) member 2 [Homo sapiens]
Length = 1019
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 27/214 (12%)
Query: 43 SVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWF 102
SVK L +S F +D P N +L+++ H L H + +
Sbjct: 17 SVKKL--QSYFAACEDEIPAIRNHDKVLQRLCEH-----------LDHALL--------Y 55
Query: 103 GYESPRS-FWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYIST 161
G + S +W + R+ I IE +++V+++ + RAW+ +AL E L Y+
Sbjct: 56 GLQDLSSGYWVLVVHFTRR---EAIKQIEVLQHVATNLGRSRAWLYLALNENSLESYLRL 112
Query: 162 ALRDFKTTRRFYEDGAIVLG-EEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTP 220
+ ++Y A+V + + ++ GL I F L LD + P + DY
Sbjct: 113 FQENLGLLHKYYVKNALVCSHDHLTLFLTLVSGLEFIRFELDLDAPYLDLA-PYMPDYYK 171
Query: 221 YLKYIQSSDSISSDEEELRTLGSSGSESSTPENV 254
+ D + S +L + S T N+
Sbjct: 172 PQYLLDFEDRLPSSVHGSDSLSLNSFNSVTSTNL 205
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 37.7 bits (86), Expect = 0.023
Identities = 48/190 (25%), Positives = 77/190 (40%), Gaps = 22/190 (11%)
Query: 283 KGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLK-N 341
K LE+ +++E +N+ L + IE L +KL KEQ + +E+++ LK +
Sbjct: 678 KSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVS 737
Query: 342 NDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLS 401
D++ + D+N LD K EK D LS +VS
Sbjct: 738 EDMKKSHDAIID-----------DLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRL 786
Query: 402 QTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCG-------SLTSVASYKSLTSLKS 454
+T P + E + N++ E K+ L CG +LTS +L + S
Sbjct: 787 ETVFVPPEKHEKEIIALKSNIV-ELKKQLSELKKKCGEDQEKIHALTS--ENTNLKKMMS 843
Query: 455 NDYLASPTTE 464
N Y+ T E
Sbjct: 844 NQYVPVKTHE 853
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 37.7 bits (86), Expect = 0.023
Identities = 48/190 (25%), Positives = 77/190 (40%), Gaps = 22/190 (11%)
Query: 283 KGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLK-N 341
K LE+ +++E +N+ L + IE L +KL KEQ + +E+++ LK +
Sbjct: 691 KSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVS 750
Query: 342 NDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLS 401
D++ + D+N LD K EK D LS +VS
Sbjct: 751 EDMKKSHDAIID-----------DLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRL 799
Query: 402 QTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCG-------SLTSVASYKSLTSLKS 454
+T P + E + N++ E K+ L CG +LTS +L + S
Sbjct: 800 ETVFVPPEKHEKEIIALKSNIV-ELKKQLSELKKKCGEDQEKIHALTS--ENTNLKKMMS 856
Query: 455 NDYLASPTTE 464
N Y+ T E
Sbjct: 857 NQYVPVKTHE 866
>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
domain 1 [Homo sapiens]
Length = 1412
Score = 37.0 bits (84), Expect = 0.039
Identities = 44/199 (22%), Positives = 88/199 (44%), Gaps = 22/199 (11%)
Query: 270 KRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYII 329
KR+++ L +QK L + + +N++ E++ + + +Q +E+ LA +KE LE I
Sbjct: 710 KRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEER-LAR--QKEVLESSI 766
Query: 330 VELQDQLTVLKNNDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYRKHN-KQWYEKSY 388
+ + ++ R Q+L HLT Q ++ + Y K K+ EK
Sbjct: 767 AHEKRKAKEALESEKRKVQDLENHLTQQ---------KEISESNIAYEKRKAKEAMEKEK 817
Query: 389 QSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKS 448
+ + L ++ Q +E + K+ +V++ D +++ + S K+
Sbjct: 818 KKVQDLENRLT--------KQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKA 869
Query: 449 LT-SLKSNDYLASPTTEMT 466
+ +LK N+ LA T T
Sbjct: 870 ESLALKLNETLAELETTKT 888
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 36.6 bits (83), Expect = 0.051
Identities = 53/227 (23%), Positives = 96/227 (42%), Gaps = 38/227 (16%)
Query: 221 YLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFN-KCKRVKQKYQLT 279
Y + ++ ++ + +D + L++L ++ T L ++ + ++ + +L
Sbjct: 1254 YSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELL 1313
Query: 280 LEQKGYLEELLRLRENQLSESVSQNKILL-QRIEDSDLAHKLEKEQLEYIIVELQDQLTV 338
+ KG LEE R +Q+ + QN+ LL Q +E DL H EQ +YI D+L
Sbjct: 1314 SQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFH---VEQRQYI-----DKLNE 1365
Query: 339 LKNNDLRSRQELTAHLTNQW----PSPGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQL 394
L+ R +++L + +Q+ PSP N + L K K + +SL
Sbjct: 1366 LR----RQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSL--- 1418
Query: 395 SAEVSLSQTSLDPGQSQEGDG--------KQDTLNVMSEGKEDTPSL 433
+L P +S +G QD+ +V S ED +L
Sbjct: 1419 ---------TLTPTRSDSSEGFLQLPHQDSQDSSSVGSNSLEDGQTL 1456
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 36.6 bits (83), Expect = 0.051
Identities = 53/227 (23%), Positives = 96/227 (42%), Gaps = 38/227 (16%)
Query: 221 YLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFN-KCKRVKQKYQLT 279
Y + ++ ++ + +D + L++L ++ T L ++ + ++ + +L
Sbjct: 1253 YSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELL 1312
Query: 280 LEQKGYLEELLRLRENQLSESVSQNKILL-QRIEDSDLAHKLEKEQLEYIIVELQDQLTV 338
+ KG LEE R +Q+ + QN+ LL Q +E DL H EQ +YI D+L
Sbjct: 1313 SQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFH---VEQRQYI-----DKLNE 1364
Query: 339 LKNNDLRSRQELTAHLTNQW----PSPGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQL 394
L+ R +++L + +Q+ PSP N + L K K + +SL
Sbjct: 1365 LR----RQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSL--- 1417
Query: 395 SAEVSLSQTSLDPGQSQEGDG--------KQDTLNVMSEGKEDTPSL 433
+L P +S +G QD+ +V S ED +L
Sbjct: 1418 ---------TLTPTRSDSSEGFLQLPHQDSQDSSSVGSNSLEDGQTL 1455
>gi|16306548 seryl-tRNA synthetase [Homo sapiens]
Length = 514
Score = 35.8 bits (81), Expect = 0.087
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 6/90 (6%)
Query: 174 EDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYL---KYIQSSDS 230
E GA+V G L G+L+ L + L+ G G P YTP+ + +Q
Sbjct: 183 EKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPI---YTPFFMRKEVMQEVAQ 239
Query: 231 ISSDEEELRTLGSSGSESSTPENVGPPFLM 260
+S +EEL + GSE S + +L+
Sbjct: 240 LSQFDEELYKVIGKGSEKSDDNSYDEKYLI 269
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 35.4 bits (80), Expect = 0.11
Identities = 41/145 (28%), Positives = 64/145 (44%), Gaps = 37/145 (25%)
Query: 236 EELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLE-------------- 281
E+++TL S + S+ N NS ++QK +LT+E
Sbjct: 583 EKIQTLKSRAAGSAQGNNQAC------NSTSEVKDLLEQKSKLTIEVAELQRQLQLEVKN 636
Query: 282 QKGYLEELLRLREN------QLSESVSQNKILLQRIEDSD----------LAHKLEKEQL 325
Q+ EE R+R N Q +E V +N L QR+E+S+ K+E+EQ
Sbjct: 637 QQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEELFQVKMEREQH 696
Query: 326 EYIIVELQDQLTVLKNN-DLRSRQE 349
+ I +LQDQL+ + + D R E
Sbjct: 697 QTEIRDLQDQLSEMHDELDSAKRSE 721
>gi|5032281 dystrophin Dp427c isoform [Homo sapiens]
Length = 3677
Score = 34.7 bits (78), Expect = 0.19
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 13/132 (9%)
Query: 218 YTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDEN------SWFNKCKR 271
Y YLK +Q D I + +RTL ++G E + ++ E W CK+
Sbjct: 2133 YKWYLKELQ--DGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQ 2190
Query: 272 VKQKYQLTLEQKGYLEELLR-LRE--NQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYI 328
+ + + EQK L E R L E L E+ + I L+ ++ L KL EQ++ +
Sbjct: 2191 LSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKL--EQVKLL 2248
Query: 329 IVELQDQLTVLK 340
+ EL + +LK
Sbjct: 2249 VEELPLRQGILK 2260
>gi|5032291 dystrophin Dp260-2 isoform [Homo sapiens]
Length = 2341
Score = 34.7 bits (78), Expect = 0.19
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 13/132 (9%)
Query: 218 YTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDEN------SWFNKCKR 271
Y YLK +Q D I + +RTL ++G E + ++ E W CK+
Sbjct: 797 YKWYLKELQ--DGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQ 854
Query: 272 VKQKYQLTLEQKGYLEELLR-LRE--NQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYI 328
+ + + EQK L E R L E L E+ + I L+ ++ L KL EQ++ +
Sbjct: 855 LSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKL--EQVKLL 912
Query: 329 IVELQDQLTVLK 340
+ EL + +LK
Sbjct: 913 VEELPLRQGILK 924
>gi|150036268 dystrophin Dp260-1 isoform [Homo sapiens]
Length = 2344
Score = 34.7 bits (78), Expect = 0.19
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 13/132 (9%)
Query: 218 YTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDEN------SWFNKCKR 271
Y YLK +Q D I + +RTL ++G E + ++ E W CK+
Sbjct: 800 YKWYLKELQ--DGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQ 857
Query: 272 VKQKYQLTLEQKGYLEELLR-LRE--NQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYI 328
+ + + EQK L E R L E L E+ + I L+ ++ L KL EQ++ +
Sbjct: 858 LSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKL--EQVKLL 915
Query: 329 IVELQDQLTVLK 340
+ EL + +LK
Sbjct: 916 VEELPLRQGILK 927
>gi|5032315 dystrophin Dp427p2 isoform [Homo sapiens]
Length = 3562
Score = 34.7 bits (78), Expect = 0.19
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 13/132 (9%)
Query: 218 YTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDEN------SWFNKCKR 271
Y YLK +Q D I + +RTL ++G E + ++ E W CK+
Sbjct: 2018 YKWYLKELQ--DGIGQRQTVVRTLNATGEEIIQQSSKTDASILQEKLGSLNLRWQEVCKQ 2075
Query: 272 VKQKYQLTLEQKGYLEELLR-LRE--NQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYI 328
+ + + EQK L E R L E L E+ + I L+ ++ L KL EQ++ +
Sbjct: 2076 LSDRKKRLEEQKNILSEFQRDLNEFVLWLEEADNIASIPLEPGKEQQLKEKL--EQVKLL 2133
Query: 329 IVELQDQLTVLK 340
+ EL + +LK
Sbjct: 2134 VEELPLRQGILK 2145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,690,003
Number of Sequences: 37866
Number of extensions: 769123
Number of successful extensions: 4343
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 95
Number of HSP's that attempted gapping in prelim test: 4193
Number of HSP's gapped (non-prelim): 225
length of query: 473
length of database: 18,247,518
effective HSP length: 106
effective length of query: 367
effective length of database: 14,233,722
effective search space: 5223775974
effective search space used: 5223775974
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.