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Search of human proteins with 198041692
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|198041692 syntaxin 16 isoform d [Homo sapiens]
(308 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|198041692 syntaxin 16 isoform d [Homo sapiens] 598 e-171
gi|47778943 syntaxin 16 isoform a [Homo sapiens] 587 e-168
gi|34447229 syntaxin 16 isoform b [Homo sapiens] 585 e-167
gi|198041688 syntaxin 16 isoform c [Homo sapiens] 581 e-166
gi|170932494 syntaxin 7 [Homo sapiens] 93 3e-19
gi|28933465 syntaxin 12 [Homo sapiens] 93 3e-19
gi|4759182 syntaxin 1A (brain) [Homo sapiens] 85 7e-17
gi|16418379 syntaxin 1B [Homo sapiens] 81 1e-15
gi|4759184 syntaxin 3 [Homo sapiens] 80 3e-15
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens] 71 1e-12
gi|20149560 syntaxin 4 [Homo sapiens] 70 3e-12
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens] 69 4e-12
gi|94400932 syntaxin 5 [Homo sapiens] 60 2e-09
gi|223972648 t-SNARE domain containing 1 [Homo sapiens] 52 5e-07
gi|33667038 syntaxin 11 [Homo sapiens] 48 1e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 45 8e-05
gi|49258196 syntaxin 19 [Homo sapiens] 41 0.002
gi|4507285 syntaxin 10 [Homo sapiens] 38 0.010
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo... 38 0.013
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof... 38 0.013
gi|13699824 kinesin family member 11 [Homo sapiens] 37 0.029
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 37 0.029
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 37 0.029
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 37 0.029
gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens] 36 0.038
gi|238908495 similar to pleckstrin homology domain protein (5V32... 35 0.064
gi|113374156 SNARE Vti1a-beta protein [Homo sapiens] 35 0.084
gi|4759188 syntaxin 8 [Homo sapiens] 35 0.11
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 34 0.19
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 34 0.19
>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
Length = 308
Score = 598 bits (1542), Expect = e-171
Identities = 308/308 (100%), Positives = 308/308 (100%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQELDELADDRMALVSGISLDPEAAIGVTKRPPPK 60
MATRRLTDAFLLLRNNSIQNRQLLAEQELDELADDRMALVSGISLDPEAAIGVTKRPPPK
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQELDELADDRMALVSGISLDPEAAIGVTKRPPPK 60
Query: 61 WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ 120
WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ
Sbjct: 61 WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ 120
Query: 121 RAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHF 180
RAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHF
Sbjct: 121 RAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHF 180
Query: 181 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 240
FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL
Sbjct: 181 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 240
Query: 241 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIV 300
GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIV
Sbjct: 241 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIV 300
Query: 301 VLVGVKSR 308
VLVGVKSR
Sbjct: 301 VLVGVKSR 308
>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
Length = 325
Score = 587 bits (1514), Expect = e-168
Identities = 308/325 (94%), Positives = 308/325 (94%), Gaps = 17/325 (5%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQ-----------------ELDELADDRMALVSGI 43
MATRRLTDAFLLLRNNSIQNRQLLAEQ ELDELADDRMALVSGI
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAAELDELADDRMALVSGI 60
Query: 44 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 103
SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH
Sbjct: 61 SLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEH 120
Query: 104 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 163
AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ
Sbjct: 121 AIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQ 180
Query: 164 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 223
SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI
Sbjct: 181 SGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREI 240
Query: 224 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 283
RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR
Sbjct: 241 RQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNR 300
Query: 284 KMLVILILFVIIIVLIVVLVGVKSR 308
KMLVILILFVIIIVLIVVLVGVKSR
Sbjct: 301 KMLVILILFVIIIVLIVVLVGVKSR 325
>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
Length = 304
Score = 585 bits (1507), Expect = e-167
Identities = 304/308 (98%), Positives = 304/308 (98%), Gaps = 4/308 (1%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQELDELADDRMALVSGISLDPEAAIGVTKRPPPK 60
MATRRLTDAFLLLRNNSIQNRQLLAEQ LADDRMALVSGISLDPEAAIGVTKRPPPK
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQ----LADDRMALVSGISLDPEAAIGVTKRPPPK 56
Query: 61 WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ 120
WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ
Sbjct: 57 WVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQ 116
Query: 121 RAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHF 180
RAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHF
Sbjct: 117 RAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHF 176
Query: 181 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 240
FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL
Sbjct: 177 FDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDL 236
Query: 241 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIV 300
GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIV
Sbjct: 237 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIV 296
Query: 301 VLVGVKSR 308
VLVGVKSR
Sbjct: 297 VLVGVKSR 304
>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
Length = 321
Score = 581 bits (1497), Expect = e-166
Identities = 304/321 (94%), Positives = 305/321 (95%), Gaps = 13/321 (4%)
Query: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQ-------------ELDELADDRMALVSGISLDP 47
MATRRLTDAFLLLRNNSIQNRQLLAEQ + LADDRMALVSGISLDP
Sbjct: 1 MATRRLTDAFLLLRNNSIQNRQLLAEQVSSHITSSPLHSRSIAALADDRMALVSGISLDP 60
Query: 48 EAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEI 107
EAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEI
Sbjct: 61 EAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEI 120
Query: 108 TTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYL 167
TTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYL
Sbjct: 121 TTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYL 180
Query: 168 KRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV 227
KRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV
Sbjct: 181 KRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV 240
Query: 228 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 287
QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV
Sbjct: 241 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 300
Query: 288 ILILFVIIIVLIVVLVGVKSR 308
ILILFVIIIVLIVVLVGVKSR
Sbjct: 301 ILILFVIIIVLIVVLVGVKSR 321
>gi|170932494 syntaxin 7 [Homo sapiens]
Length = 261
Score = 93.2 bits (230), Expect = 3e-19
Identities = 73/237 (30%), Positives = 115/237 (48%), Gaps = 14/237 (5%)
Query: 77 QKMKELASLHDKHLNR-PTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSE 135
QK+ + + + LN+ T DS E ++ Q QL + ++ S SE
Sbjct: 23 QKITQCSVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKEFGSLPTTPSE 82
Query: 136 QEGRLL--GNVVASLAQALQELSTSFRHAQSGYLKRMKN--REERSQHFFDTSVPLMDDG 191
Q R + +VA +L T+F+ Q +R K R+ S P
Sbjct: 83 QRQRKIQKDRLVAEFTTSL----TNFQKVQRQAAEREKEFVARVRASSRVSGSFPEDSSK 138
Query: 192 DDNTLYHRGFTEDQLV-----LVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVE 246
+ N + T+ Q+ + E + ++ ERE IRQ+ I D+NEIF+DLG MI E
Sbjct: 139 ERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMMIHE 198
Query: 247 QGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 303
QG V+D I+ NVE + + + +QL +A YQ+K+RK L I+IL ++I V I+ L+
Sbjct: 199 QGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLI 255
>gi|28933465 syntaxin 12 [Homo sapiens]
Length = 276
Score = 93.2 bits (230), Expect = 3e-19
Identities = 75/256 (29%), Positives = 132/256 (51%), Gaps = 15/256 (5%)
Query: 59 PKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSS---EEEHAIEITTQEITQL 115
P+ D IQ G I++ + A + + T DSS E ++ +T ++ +
Sbjct: 17 PQLRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQENLQQLQHSTNQLAKE 76
Query: 116 FHRCQRAVQALP-----SRARACSEQEGRLLGNVVASLA--QALQELSTSFRHAQSGYLK 168
+ + + +LP S R Q+ RL+ + A+L QA+Q S + +S
Sbjct: 77 TNELLKELGSLPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQR-RVSEKEKESIARA 135
Query: 169 RMKNREERSQHFFDTSVPLMDDGDD-NTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV 227
R +R + + + D ++ N + + ED++ + EQ+ +++ERE IRQ+
Sbjct: 136 RAGSRLSAEERQREEQLVSFDSHEEWNQMQSQ---EDEVAITEQDLELIKERETAIRQLE 192
Query: 228 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 287
I D+N+IF+DL MI +QG ++D I+ NVE S + E +QL +A YQKK+RK +
Sbjct: 193 ADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMC 252
Query: 288 ILILFVIIIVLIVVLV 303
IL+L + +I+LI+ L+
Sbjct: 253 ILVLVLSVIILILGLI 268
>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
Length = 288
Score = 85.1 bits (209), Expect = 7e-17
Identities = 69/274 (25%), Positives = 138/274 (50%), Gaps = 21/274 (7%)
Query: 46 DPEAAIGVTK-RPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHA 104
D + A+ V + R ++ + V+EI+ + +I + ++E+ H L P D+ ++EE
Sbjct: 17 DDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEE-- 74
Query: 105 IEITTQEITQLFHRCQRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELS 156
+E +I + ++ + ++++ ++ ++EG R+ ++L++ E+
Sbjct: 75 LEELMSDIKKTANKVRSKLKSIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVM 131
Query: 157 TSFRHAQSGYLKRMKNREERSQHFFD---TSVPLMD--DGDDNTLYHRGFTEDQLVLVEQ 211
+ + QS Y +R K R +R TS L D + + ++ G D + +Q
Sbjct: 132 SEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSIS-KQ 190
Query: 212 NTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQ 271
+E R EI ++ SI +L+++F D+ ++ QG ++DRI+YNVE + E +
Sbjct: 191 ALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSD 250
Query: 272 LHKAEQYQKK-NRKMLVILILFVIIIVLIVVLVG 304
KA +YQ K RK ++I+I VI+ ++I VG
Sbjct: 251 TKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284
>gi|16418379 syntaxin 1B [Homo sapiens]
Length = 288
Score = 81.3 bits (199), Expect = 1e-15
Identities = 65/260 (25%), Positives = 133/260 (51%), Gaps = 22/260 (8%)
Query: 60 KWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRC 119
++ + V+EI+ + ++ + ++++ H L P D+ +++E +E T +I + ++
Sbjct: 31 EFFEQVEEIRGCIEKLSEDVEQVKKQHSAILAAPNPDEKTKQE--LEDLTADIKKTANKV 88
Query: 120 QRAVQALPSRARACSEQEG--------RLLGNVVASLAQALQELSTSFRHAQSGYLKRMK 171
+ ++A+ ++ ++EG R+ ++L++ E+ T + QS Y R K
Sbjct: 89 RSKLKAIE---QSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMTEYNATQSKYRDRCK 145
Query: 172 NREERSQHFFD---TSVPLMDDGDDNTLYHRGFTEDQLV---LVEQNTLMVEEREREIRQ 225
+R +R T+ L D + L FT+D + + +Q +E R EI +
Sbjct: 146 DRIQRQLEITGRTTTNEELEDMLESGKLAI--FTDDIKMDSQMTKQALNEIETRHNEIIK 203
Query: 226 IVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRK 284
+ SI +L+++F D+ ++ QG ++DRI+YNVE S E + KA +YQ K RK
Sbjct: 204 LETSIRELHDMFVDMAMLVESQGEMIDRIEYNVEHSVDYVERAVSDTKKAVKYQSKARRK 263
Query: 285 MLVILILFVIIIVLIVVLVG 304
++I+I V++ V++ +G
Sbjct: 264 KIMIIICCVVLGVVLASSIG 283
>gi|4759184 syntaxin 3 [Homo sapiens]
Length = 289
Score = 79.7 bits (195), Expect = 3e-15
Identities = 54/247 (21%), Positives = 124/247 (50%), Gaps = 12/247 (4%)
Query: 65 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 124
++E + ++ +I + ++E L+ L+ P + ++++ +E T EI + + + ++
Sbjct: 39 IEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDD--LEQLTTEIKKRANNVRNKLK 96
Query: 125 ALPSRAR---ACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFF 181
++ S + R+ + + L++ E+ T + AQ + +R K R +R
Sbjct: 97 SMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEIT 156
Query: 182 -----DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEI 236
D + M + + ++ G + Q+ +Q +E R ++I ++ SI +L+++
Sbjct: 157 GKKTTDEELEEMLESGNPAIFTSGIIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDM 214
Query: 237 FRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIII 296
F D+ ++ QG +LD I+ NV + E + KA +YQ + RK L+I+I+ V+++
Sbjct: 215 FMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVL 274
Query: 297 VLIVVLV 303
+ I+ L+
Sbjct: 275 LGILALI 281
>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
Length = 287
Score = 70.9 bits (172), Expect = 1e-12
Identities = 54/250 (21%), Positives = 121/250 (48%), Gaps = 15/250 (6%)
Query: 65 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 124
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
Query: 125 ALPS-----RARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 179
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
Query: 180 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 233
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
Query: 234 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFV 293
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K R+ L+ +I+ V
Sbjct: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKLMFIIICV 271
Query: 294 IIIVLIVVLV 303
I++++I+ ++
Sbjct: 272 IVLLVILGII 281
>gi|20149560 syntaxin 4 [Homo sapiens]
Length = 297
Score = 69.7 bits (169), Expect = 3e-12
Identities = 77/306 (25%), Positives = 142/306 (46%), Gaps = 26/306 (8%)
Query: 13 LRNNSIQNRQLLAEQELDELADDRMALVSGISLDPEAA-IGVTKRPPPKWVDGVDEIQYD 71
+R+ + + RQ + DE +R+ALV + P A +G P ++ V I+
Sbjct: 1 MRDRTHELRQ--GDDSSDEEDKERVALV----VHPGTARLG---SPDEEFFHKVRTIRQT 51
Query: 72 VGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRAR 131
+ ++ K++EL L P ++S ++E ++ EI QL + ++A+ +
Sbjct: 52 IVKLGNKVQELEKQQVTILATPLPEESMKQE--LQNLRDEIKQLGREIRLQLKAIEPQKE 109
Query: 132 ACSEQEG----RLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPL 187
E R+ L+Q EL QS Y R KN E + T+ +
Sbjct: 110 EADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEY--REKNVERIRRQLKITNAGM 167
Query: 188 MDDGDDNTLYHRGFTEDQLVLVEQNTLMVEE-------REREIRQIVQSISDLNEIFRDL 240
+ D + + G +E + + ++T + + R EI+Q+ +SI +L++IF L
Sbjct: 168 VSDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFL 227
Query: 241 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFV-IIIVLI 299
+ QG +++RI+ N+ S E G + + A + QKK RK V++ + V I +VL+
Sbjct: 228 ATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLL 287
Query: 300 VVLVGV 305
V++GV
Sbjct: 288 AVIIGV 293
>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
Length = 288
Score = 69.3 bits (168), Expect = 4e-12
Identities = 54/253 (21%), Positives = 121/253 (47%), Gaps = 16/253 (6%)
Query: 65 VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 124
V+EI+ + +I Q ++E+ H L+ P + +EE +E +EI + ++ + ++
Sbjct: 36 VEEIRNSIDKITQYVEEVKKNHSIILSAPNPEGKIKEE--LEDLNKEIKKTANKIRAKLK 93
Query: 125 AL-----PSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQH 179
A+ + + + R+ + L++ E + AQ+ + +R K R +R
Sbjct: 94 AIEQSFDQDESGNRTSVDLRIRRTQHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLE 153
Query: 180 FF------DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDL 233
D +++ G + ++ Q+ N +E R ++I ++ SI +L
Sbjct: 154 ITGRTTTDDELEEMLESGKPSIFTSDIISDSQITRQALNE--IESRHKDIMKLETSIREL 211
Query: 234 NEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKK-NRKMLVILILF 292
+E+F D+ + QG +++ I+ NV + E ++ KA +YQ K RK +I+ +
Sbjct: 212 HEMFMDMAMFVETQGEMINNIERNVMNATDYVEHAKEETKKAIKYQSKARRKKWIIIAVS 271
Query: 293 VIIIVLIVVLVGV 305
V+++ +I +++G+
Sbjct: 272 VVLVAIIALIIGL 284
>gi|94400932 syntaxin 5 [Homo sapiens]
Length = 355
Score = 60.1 bits (144), Expect = 2e-09
Identities = 61/255 (23%), Positives = 107/255 (41%), Gaps = 29/255 (11%)
Query: 71 DVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRA 130
D+ K+++L L + + DD + E IE T I Q + + + L
Sbjct: 104 DLSNTFAKLEKLTILAKR---KSLFDDKAVE---IEELTYIIKQDINSLNKQIAQLQDFV 157
Query: 131 RACSEQEGRLL----GNVVASLAQALQELSTSFR---HAQSGYLKRMKNREERSQHFFDT 183
RA Q GR L +V SL L +S F+ ++ LK+ ++R E+ +
Sbjct: 158 RAKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTENLKQQRSRREQFSRAPVS 217
Query: 184 SVPLMDDGDDNTLYHRGF----------------TEDQLVLVEQNTLMVEEREREIRQIV 227
++PL + G T QL L+++ ++ R ++ I
Sbjct: 218 ALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSRTSQQLQLIDEQDSYIQSRADTMQNIE 277
Query: 228 QSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLV 287
+I +L IF+ L M+ EQ + RID NV + + E ++ K Q NR ++V
Sbjct: 278 STIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAHSEILKYFQSVTSNRWLMV 337
Query: 288 ILILFVIIIVLIVVL 302
+ L +I+ +I V+
Sbjct: 338 KIFLILIVFFIIFVV 352
>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
Length = 513
Score = 52.4 bits (124), Expect = 5e-07
Identities = 58/278 (20%), Positives = 113/278 (40%), Gaps = 28/278 (10%)
Query: 42 GISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEE 101
G SL+P A T+ P + E+ +V RI + SL + T D+ E
Sbjct: 241 GFSLEPPRA---TQVDPCNLQELFQEMSANVFRINSSV---TSLERSLQSLGTPSDTQEL 294
Query: 102 EHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRH 161
++ QE + +V+ + R+ QE + L L T
Sbjct: 295 RDSLHTAQQETNKTIAASASSVKQMAELLRSSCPQER------LQQERPQLDRLKTQLSD 348
Query: 162 AQSGYLKRMKNREERSQHFFDTS---------VPLMDDGDDNTLYHRGFT----EDQLVL 208
A Y K E+S+ + P + DD +++ ++Q +L
Sbjct: 349 AIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQGQEQALL 408
Query: 209 ---VEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKT 265
E++ + RE I Q+ ++ D+N+I +DL +M+ EQG +D I+ ++E +
Sbjct: 409 PDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHA 468
Query: 266 EDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 303
E + L A ++Q + K+ + + +L+++++
Sbjct: 469 EAARQLLAGASRHQLQRHKIKCCFLSAGVTALLVIIII 506
>gi|33667038 syntaxin 11 [Homo sapiens]
Length = 287
Score = 48.1 bits (113), Expect = 1e-05
Identities = 54/225 (24%), Positives = 102/225 (45%), Gaps = 25/225 (11%)
Query: 71 DVGRI-KQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSR 129
DV R+ KQ + L S+ L + ++I + ++ H RA++ L
Sbjct: 61 DVKRLGKQNARFLTSMR-------RLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEA 113
Query: 130 ARACSEQEGRLLGNVVASLAQA-LQELSTSFRHAQSGY----LKRMKNREERSQHFFDTS 184
A A Q G + VA +++A L+ +F+ A Y +K+ N + R Q +
Sbjct: 114 AEA---QHGP--HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIM 168
Query: 185 VPLMDDGDDNTLYHRG----FTEDQLVLVEQNTLM---VEEREREIRQIVQSISDLNEIF 237
+ ++ +G F+E+ L V+ +E R RE+ ++ I D++E+F
Sbjct: 169 GKEVSGDQIEDMFEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELF 228
Query: 238 RDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 282
+ ++ +Q L+ I+ NV+++ T Q+ KA QY++KN
Sbjct: 229 LQMAVLVEKQADTLNVIELNVQKTVDYTGQAKAQVRKAVQYEEKN 273
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 45.1 bits (105), Expect = 8e-05
Identities = 60/274 (21%), Positives = 112/274 (40%), Gaps = 30/274 (10%)
Query: 18 IQNRQLLAEQELDELADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQ 77
+ N L E+E ++L D+ L S + EA I + K V ++ ++K
Sbjct: 237 MDNMTLERERESEKLKDECKKLQSQYA-SSEATISQLRSELAKGPQEVAVYVQELQKLKS 295
Query: 78 KMKELA----SLHDKHLNRPTLDDSSEEEHAIE-ITTQEITQLFHRCQRAVQALPSRARA 132
+ EL +L + L + EE+H E ++ + I H+ Q L SR A
Sbjct: 296 SVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSA 355
Query: 133 CSEQEGRL------LGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVP 186
R+ G L + L E+ T ++H ++ + + + REE+ QH
Sbjct: 356 SETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQH------G 409
Query: 187 LMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIV---QSISDLNEIFRDLGAM 243
L + N L H E + L E + + E+R+ +++ Q ++DL L
Sbjct: 410 LQLQSEINQL-HSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQ 468
Query: 244 IVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQ 277
+ E+ T + + ++++ KQ H+ +Q
Sbjct: 469 LKEKVTNSTELQHQLDKT--------KQQHQEQQ 494
>gi|49258196 syntaxin 19 [Homo sapiens]
Length = 294
Score = 40.8 bits (94), Expect = 0.002
Identities = 25/102 (24%), Positives = 51/102 (50%), Gaps = 7/102 (6%)
Query: 188 MDDGDDNTLYHRGFTE--DQLVLVEQNTLM-----VEEREREIRQIVQSISDLNEIFRDL 240
M + D N + H+G E ++ +L E N +E+R +E+ + I DL ++F +
Sbjct: 177 MSEEDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQI 236
Query: 241 GAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKN 282
++ EQG ++ I+ V + + ++ A +Y+K+N
Sbjct: 237 SLLVEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKRN 278
>gi|4507285 syntaxin 10 [Homo sapiens]
Length = 249
Score = 38.1 bits (87), Expect = 0.010
Identities = 18/89 (20%), Positives = 48/89 (53%)
Query: 214 LMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLH 273
L+++E+++++ + SI L + +G + EQG +LD ++ + + + L++L
Sbjct: 158 LIMDEQDQQLEMVSGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDGVLRKLA 217
Query: 274 KAEQYQKKNRKMLVILILFVIIIVLIVVL 302
K R+ I +L ++++++++L
Sbjct: 218 KVSHMTSDRRQWCAIAVLVGVLLLVLILL 246
>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
[Homo sapiens]
Length = 8749
Score = 37.7 bits (86), Expect = 0.013
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 42/179 (23%)
Query: 105 IEITTQEITQLFHRCQRAVQALPSRA--RACSEQEG-RLLGNVVASLAQALQELSTSFRH 161
IE+TTQ +++L + R + A A S Q+G R + + VA L +A+ EL+
Sbjct: 4609 IELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELN----- 4663
Query: 162 AQSGYLKRMKNREERSQHFFDTSVPLMDDGDDN--TLYHR--GFTEDQLVLVEQNTL--- 214
++ + F T P D + TLYHR TE ++ L+E T
Sbjct: 4664 -------------QKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQ 4710
Query: 215 ----MVEEREREIRQIVQSISDLNE----------IFRDLGAMIVEQGTVLDRIDYNVE 259
M ++ ER+++ + + S +NE ++ L + + G VL R+ ++E
Sbjct: 4711 EHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLE 4769
>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
[Homo sapiens]
Length = 8797
Score = 37.7 bits (86), Expect = 0.013
Identities = 45/179 (25%), Positives = 79/179 (44%), Gaps = 42/179 (23%)
Query: 105 IEITTQEITQLFHRCQRAVQALPSRA--RACSEQEG-RLLGNVVASLAQALQELSTSFRH 161
IE+TTQ +++L + R + A A S Q+G R + + VA L +A+ EL+
Sbjct: 4680 IELTTQSLSELEAQFLRMSKVPTDLAVEEALSLQDGCRAILDEVAGLGEAVDELN----- 4734
Query: 162 AQSGYLKRMKNREERSQHFFDTSVPLMDDGDDN--TLYHR--GFTEDQLVLVEQNTL--- 214
++ + F T P D + TLYHR TE ++ L+E T
Sbjct: 4735 -------------QKKEGFRSTGQPWQPDKMLHLVTLYHRLKRQTEQRVSLLEDTTSAYQ 4781
Query: 215 ----MVEEREREIRQIVQSISDLNE----------IFRDLGAMIVEQGTVLDRIDYNVE 259
M ++ ER+++ + + S +NE ++ L + + G VL R+ ++E
Sbjct: 4782 EHEKMCQQLERQLKSVKEEQSKVNEETLPAEEKLKMYHSLAGSLQDSGIVLKRVTIHLE 4840
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 36.6 bits (83), Expect = 0.029
Identities = 33/159 (20%), Positives = 70/159 (44%), Gaps = 16/159 (10%)
Query: 5 RLTDAFLLLRN------NSIQNRQLLAEQELDELADDRMALVSGISLDPEAAIGVTKRPP 58
R+T+ F+ +N + +QN+ E L + ++ LV E +
Sbjct: 435 RVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVK-----EEYITSALESTE 489
Query: 59 PKWVDGVDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHR 118
K D ++ + +++ K+++ LH K + +D + E A +I + + LF+
Sbjct: 490 EKLHDAASKL---LNTVEETTKDVSGLHSKLDRKKAVDQHNAE--AQDIFGKNLNSLFNN 544
Query: 119 CQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELST 157
+ ++ S+ +A E L GN+++S AL ++T
Sbjct: 545 MEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITT 583
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 36.6 bits (83), Expect = 0.029
Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 25/203 (12%)
Query: 86 HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVV 145
H+K L EE AI + Q+FH+ Q A +L + A + EG+ V+
Sbjct: 335 HEKQDTLVALRQQLEEVKAINL------QMFHKAQNAESSLQQKNEAITSFEGK-TNQVM 387
Query: 146 ASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQ 205
+S+ Q + L S R Q + K ++E + L + + + ++
Sbjct: 388 SSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEK 447
Query: 206 LVLVEQNTLMVEERERE------IRQIVQSISDLNEIFR-------DLGAMIVEQGTVLD 252
EQ + E + E +R +Q + L + R +L + EQ L
Sbjct: 448 ----EQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQ 503
Query: 253 RIDYNVEQSCIKTEDGLKQLHKA 275
+ ++ QS +K ED +K++++A
Sbjct: 504 EMGLHLSQSKLKMED-IKEVNQA 525
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 36.6 bits (83), Expect = 0.029
Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 25/203 (12%)
Query: 86 HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVV 145
H+K L EE AI + Q+FH+ Q A +L + A + EG+ V+
Sbjct: 335 HEKQDTLVALRQQLEEVKAINL------QMFHKAQNAESSLQQKNEAITSFEGK-TNQVM 387
Query: 146 ASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQ 205
+S+ Q + L S R Q + K ++E + L + + + ++
Sbjct: 388 SSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEK 447
Query: 206 LVLVEQNTLMVEERERE------IRQIVQSISDLNEIFR-------DLGAMIVEQGTVLD 252
EQ + E + E +R +Q + L + R +L + EQ L
Sbjct: 448 ----EQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQ 503
Query: 253 RIDYNVEQSCIKTEDGLKQLHKA 275
+ ++ QS +K ED +K++++A
Sbjct: 504 EMGLHLSQSKLKMED-IKEVNQA 525
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 36.6 bits (83), Expect = 0.029
Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 25/203 (12%)
Query: 86 HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVV 145
H+K L EE AI + Q+FH+ Q A +L + A + EG+ V+
Sbjct: 443 HEKQDTLVALRQQLEEVKAINL------QMFHKAQNAESSLQQKNEAITSFEGK-TNQVM 495
Query: 146 ASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQ 205
+S+ Q + L S R Q + K ++E + L + + + ++
Sbjct: 496 SSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEK 555
Query: 206 LVLVEQNTLMVEERERE------IRQIVQSISDLNEIFR-------DLGAMIVEQGTVLD 252
EQ + E + E +R +Q + L + R +L + EQ L
Sbjct: 556 ----EQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQ 611
Query: 253 RIDYNVEQSCIKTEDGLKQLHKA 275
+ ++ QS +K ED +K++++A
Sbjct: 612 EMGLHLSQSKLKMED-IKEVNQA 633
>gi|111955162 5-azacytidine induced 1 isoform b [Homo sapiens]
Length = 1044
Score = 36.2 bits (82), Expect = 0.038
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 11/124 (8%)
Query: 54 TKRPPPKWVDGVD-EIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEI 112
TK+ V G++ EIQ + R KQ+++ L SLH+ L +E A + ++
Sbjct: 697 TKKIKEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAEL-------LQSDERASQRCLRQA 749
Query: 113 TQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKN 172
+L + +R +AL + R + Q R + L Q L+E S++ A ++ +
Sbjct: 750 EELREQLEREKEALGQQERERARQRQRA---ELEELRQQLEESSSALTRALRAEFEKGRE 806
Query: 173 REER 176
+ER
Sbjct: 807 EQER 810
>gi|238908495 similar to pleckstrin homology domain protein (5V327)
[Homo sapiens]
Length = 506
Score = 35.4 bits (80), Expect = 0.064
Identities = 32/162 (19%), Positives = 76/162 (46%), Gaps = 11/162 (6%)
Query: 26 EQELDELADDRMALVSGISLDP---EAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKEL 82
+Q L+EL+ ++ + + + + +++PPP + ++ +I++KM++L
Sbjct: 244 QQTLEELSIEKKKTLEMLEENENHLQTLANQSEQPPPS-----GGLHSNLRQIEEKMQQL 298
Query: 83 ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLG 142
L +K L + ++ E A+E + + Q ++Q L + + +E+E +
Sbjct: 299 --LEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNSLQELTAEKQQ-AERELKAEV 355
Query: 143 NVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTS 184
V L + L+E + R + G +++N+E+ + D S
Sbjct: 356 KVRMDLERRLREAEGALRSLEQGLNSKVRNKEKEERMRADVS 397
Score = 30.4 bits (67), Expect = 2.1
Identities = 46/221 (20%), Positives = 94/221 (42%), Gaps = 10/221 (4%)
Query: 20 NRQLLAEQELDELADDRMALVSGISLDPEAAIG--VTKRPPPKWVDGVDEIQYDVGRIKQ 77
N L AE E ++ M SG A +G + K + + E Q + ++ +
Sbjct: 113 NILLAAESEFEQTQWLEMLQESGKVTWKNAQLGEAMIKSLEAQGLQLAKEKQEYLDKLME 172
Query: 78 KMKELASLHDKHLNRPTLDDSSE-EEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQ 136
+ +EL ++ L+ E E+ E QE+ + +R ++ L +R EQ
Sbjct: 173 ETEELCLQREQREELERLNQVLEAEKQQFEEVVQELRMEQEQIKRELE-LTARCLKGVEQ 231
Query: 137 EGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTL 196
E + L ++ SL Q L+ELS + L+ ++ E Q + S G ++
Sbjct: 232 EKKELRHLTESLQQTLEELSIEKKKT----LEMLEENENHLQTLANQSEQPPPSGGLHSN 287
Query: 197 YHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIF 237
+ E+++ + + L+ E+R +E + +++ + E +
Sbjct: 288 LRQ--IEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFY 326
>gi|113374156 SNARE Vti1a-beta protein [Homo sapiens]
Length = 217
Score = 35.0 bits (79), Expect = 0.084
Identities = 39/211 (18%), Positives = 84/211 (39%), Gaps = 27/211 (12%)
Query: 96 DDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRARACSEQEGRLLGNVVASLAQALQEL 155
D+ + +E +E +L + V+ +P ++R + N + S Q + +L
Sbjct: 32 DEKKQMVANVEKQLEEAKELLEQMDLEVREIPPQSRG-------MYSNRMRSYKQEMGKL 84
Query: 156 STSFRHAQSGYLKRMKNREERSQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLM 215
T F+ ++ Y ++N L DDG+ + E+Q + NT
Sbjct: 85 ETDFKRSRIAYSDEVRNEL------------LGDDGNSS--------ENQRAHLLDNTER 124
Query: 216 VEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKA 275
+E R + Q + +I +++ + + R + ++ + L
Sbjct: 125 LERSSRRLEAGYQIAVETEQIGQEMLENLSHDREKIQRARERLRETDANLGKSSRILTGM 184
Query: 276 EQYQKKNRKMLVILILFVIIIVLIVVLVGVK 306
+ +NR +LVIL + V+I +L+ + V+
Sbjct: 185 LRRIIQNRILLVILGIIVVITILMAITFSVR 215
>gi|4759188 syntaxin 8 [Homo sapiens]
Length = 236
Score = 34.7 bits (78), Expect = 0.11
Identities = 19/91 (20%), Positives = 49/91 (53%)
Query: 210 EQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGL 269
+Q +++E++ + + IS ++ +++G + EQ ++D + VE + K +
Sbjct: 142 QQQQKIIQEQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKLRNET 201
Query: 270 KQLHKAEQYQKKNRKMLVILILFVIIIVLIV 300
++++ ++ ++VIL+L V I+V+ V
Sbjct: 202 RRVNMVDRKSASCGMIMVILLLLVAIVVVAV 232
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 33.9 bits (76), Expect = 0.19
Identities = 62/283 (21%), Positives = 118/283 (41%), Gaps = 39/283 (13%)
Query: 21 RQLLAEQELDELADD-------RMALVSGIS-LDPEAAIGVTKRPPPKWVDGVDEIQYDV 72
++L AEQEL L + R L ++ L EAA KR E++ ++
Sbjct: 1707 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR---------QELEAEL 1757
Query: 73 GRIKQKMKEL--ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRA 130
+++ +M+ L + + +R T + S + A +E+ + R RA+ R
Sbjct: 1758 AKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQ 1816
Query: 131 RACSEQEG--------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-R 176
R +E++ R+L +A++ +A + E++ + A++ L+R+ E +
Sbjct: 1817 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ 1876
Query: 177 SQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEI 236
+ + + D ++ R ++ +L E+ +VE+ R+ RQ+ + I L
Sbjct: 1877 RRRLEEQAAQHKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKAS 1933
Query: 237 FRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 279
F A E L RI N E + E +L A Q Q
Sbjct: 1934 FEKAAAGKAELELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 1974
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 33.9 bits (76), Expect = 0.19
Identities = 62/283 (21%), Positives = 118/283 (41%), Gaps = 39/283 (13%)
Query: 21 RQLLAEQELDELADD-------RMALVSGIS-LDPEAAIGVTKRPPPKWVDGVDEIQYDV 72
++L AEQEL L + R L ++ L EAA KR E++ ++
Sbjct: 1711 QRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR---------QELEAEL 1761
Query: 73 GRIKQKMKEL--ASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRA 130
+++ +M+ L + + +R T + S + A +E+ + R RA+ R
Sbjct: 1762 AKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARL-RALAEEAKRQ 1820
Query: 131 RACSEQEG--------RLLGNVVASLAQALQ-----ELSTSFRHAQSGYLKRMKNREE-R 176
R +E++ R+L +A++ +A + E++ + A++ L+R+ E +
Sbjct: 1821 RQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQ 1880
Query: 177 SQHFFDTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEI 236
+ + + D ++ R ++ +L E+ +VE+ R+ RQ+ + I L
Sbjct: 1881 RRRLEEQAAQHKADIEERLAQLRKASDSEL---ERQKGLVEDTLRQRRQVEEEILALKAS 1937
Query: 237 FRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQ 279
F A E L RI N E + E +L A Q Q
Sbjct: 1938 FEKAAAGKAELELELGRIRSNAEDTLRSKEQA--ELEAARQRQ 1978
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,205,212
Number of Sequences: 37866
Number of extensions: 414302
Number of successful extensions: 1921
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 66
Number of HSP's that attempted gapping in prelim test: 1834
Number of HSP's gapped (non-prelim): 154
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.