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Search of human proteins with 197276654
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|197276654 myeloid differentiation primary response gene 88
[Homo sapiens]
(309 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|197276654 myeloid differentiation primary response gene 88 [H... 622 e-178
gi|19718734 toll-like receptor 2 [Homo sapiens] 54 2e-07
gi|19924149 toll-like receptor 4 precursor [Homo sapiens] 52 5e-07
gi|22547219 Toll-interleukin 1 receptor domain-containing adapto... 52 5e-07
gi|89111122 Toll-interleukin 1 receptor domain-containing adapto... 52 5e-07
gi|4504661 interleukin 1 receptor accessory protein isoform 1 [H... 50 2e-06
gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens] 47 2e-05
gi|205277451 single Ig IL-1R-related molecule [Homo sapiens] 45 1e-04
gi|205277449 single Ig IL-1R-related molecule [Homo sapiens] 45 1e-04
gi|205277445 single Ig IL-1R-related molecule [Homo sapiens] 45 1e-04
gi|20143971 toll-like receptor 6 [Homo sapiens] 41 0.001
gi|7706093 toll-like receptor 7 [Homo sapiens] 40 0.003
gi|16751843 toll-like receptor 5 [Homo sapiens] 40 0.003
gi|16933525 unc5C [Homo sapiens] 39 0.004
gi|11225607 interleukin 1 receptor accessory protein-like 2 [Hom... 39 0.008
gi|41350337 toll-like receptor 1 [Homo sapiens] 38 0.010
gi|4504657 interleukin 18 receptor accessory protein precursor [... 37 0.017
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens] 37 0.017
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens] 37 0.017
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 37 0.017
gi|89363047 death-associated protein kinase 1 [Homo sapiens] 37 0.029
gi|32261318 unc-5 homolog B [Homo sapiens] 36 0.038
gi|61742786 leucine rich repeat and death domain containing prot... 35 0.084
gi|61742784 leucine rich repeat and death domain containing prot... 35 0.084
gi|61742782 leucine rich repeat and death domain containing prot... 35 0.084
gi|31442420 shroom family member 1 [Homo sapiens] 35 0.11
gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [H... 34 0.19
gi|169203406 PREDICTED: hypothetical protein [Homo sapiens] 32 0.55
gi|169202578 PREDICTED: hypothetical protein [Homo sapiens] 32 0.55
gi|4507531 toll-like receptor 3 [Homo sapiens] 32 0.71
>gi|197276654 myeloid differentiation primary response gene 88 [Homo
sapiens]
Length = 309
Score = 622 bits (1603), Expect = e-178
Identities = 309/309 (100%), Positives = 309/309 (100%)
Query: 1 MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADW 60
MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADW
Sbjct: 1 MRPDRAEAPGPPAMAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFLNVRTQVAADW 60
Query: 61 TALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGP 120
TALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGP
Sbjct: 61 TALAEEMDFEYLEIRQLETQADPTGRLLDAWQGRPGASVGRLLELLTKLGRDDVLLELGP 120
Query: 121 SIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICY 180
SIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICY
Sbjct: 121 SIEEDCQKYILKQQQEEAEKPLQVAAVDSSVPRTAELAGITTLDDPLGHMPERFDAFICY 180
Query: 181 CPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDY 240
CPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDY
Sbjct: 181 CPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDY 240
Query: 241 LQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWT 300
LQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWT
Sbjct: 241 LQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNPCTKSWFWT 300
Query: 301 RLAKALSLP 309
RLAKALSLP
Sbjct: 301 RLAKALSLP 309
>gi|19718734 toll-like receptor 2 [Homo sapiens]
Length = 784
Score = 53.9 bits (128), Expect = 2e-07
Identities = 38/143 (26%), Positives = 70/143 (48%), Gaps = 11/143 (7%)
Query: 174 FDAFICYCPSDIQFVQE-MIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRM 232
+DAF+ Y D +V+ M+++LE N KLC+ RD +PG + + IEK +
Sbjct: 641 YDAFVSYSERDAYWVENLMVQELENFNPPFKLCLHKRDFIPGKWIIDNIIDSIEK-SHKT 699
Query: 233 VVVVSDDYLQSKECDFQTKFAL-----SLSPGAHQKRLIPIKYKAMKKEFPSILRFITVC 287
V V+S+++++S+ C ++ F+ + A L PI+ KA+ + F + + +
Sbjct: 700 VFVLSENFVKSEWCKYELDFSHFRLFDENNDAAILILLEPIEKKAIPQRFCKLRKIMNTK 759
Query: 288 DY----TNPCTKSWFWTRLAKAL 306
Y + + FW L A+
Sbjct: 760 TYLEWPMDEAQREGFWVNLRAAI 782
>gi|19924149 toll-like receptor 4 precursor [Homo sapiens]
Length = 839
Score = 52.4 bits (124), Expect = 5e-07
Identities = 41/145 (28%), Positives = 77/145 (53%), Gaps = 15/145 (10%)
Query: 174 FDAFICYCPSDIQFVQ-EMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEK---RC 229
+DAF+ Y D +V+ E+++ LE+ +LC+ RD +PG +IA+ +I + +
Sbjct: 674 YDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGV---AIAANIIHEGFHKS 730
Query: 230 RRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKK-------EFPSILR 282
R+++VVVS ++QS+ C F+ + A + + + +I I + ++K E +L
Sbjct: 731 RKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLS 790
Query: 283 FITVCDYTNPCT-KSWFWTRLAKAL 306
T ++ + + FW RL KAL
Sbjct: 791 RNTYLEWEDSVLGRHIFWRRLRKAL 815
>gi|22547219 Toll-interleukin 1 receptor domain-containing adaptor
protein isoform b [Homo sapiens]
Length = 235
Score = 52.4 bits (124), Expect = 5e-07
Identities = 43/178 (24%), Positives = 81/178 (45%), Gaps = 19/178 (10%)
Query: 130 ILKQQQEEAEKPLQVAAVDSSVPRTAE------LAGITTLDDPLGHMPER--------FD 175
+LK+ ++ P ++ D+S P + + L+ +T+ P H + +D
Sbjct: 29 LLKKPKKRPNSPESTSS-DASQPTSQDSPLPPSLSSVTSPSLPPTHASDSGSSRWSKDYD 87
Query: 176 AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWS-IASELIEKRCRRMVV 234
+C+ D+ Q+++ LE + L+ + RD PG + S + L CR V+
Sbjct: 88 VCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCR--VL 145
Query: 235 VVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNP 292
+++ +LQ C +Q AL+ +PGA + IP+ + +P LRF+ D P
Sbjct: 146 LITPGFLQDPWCKYQMLQALTEAPGA-EGCTIPLLSGLSRAAYPPELRFMYYVDGRGP 202
>gi|89111122 Toll-interleukin 1 receptor domain-containing adaptor
protein isoform a [Homo sapiens]
Length = 221
Score = 52.4 bits (124), Expect = 5e-07
Identities = 43/178 (24%), Positives = 81/178 (45%), Gaps = 19/178 (10%)
Query: 130 ILKQQQEEAEKPLQVAAVDSSVPRTAE------LAGITTLDDPLGHMPER--------FD 175
+LK+ ++ P ++ D+S P + + L+ +T+ P H + +D
Sbjct: 29 LLKKPKKRPNSPESTSS-DASQPTSQDSPLPPSLSSVTSPSLPPTHASDSGSSRWSKDYD 87
Query: 176 AFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWS-IASELIEKRCRRMVV 234
+C+ D+ Q+++ LE + L+ + RD PG + S + L CR V+
Sbjct: 88 VCVCHSEEDLVAAQDLVSYLEGSTASLRCFLQLRDATPGGAIVSELCQALSSSHCR--VL 145
Query: 235 VVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRFITVCDYTNP 292
+++ +LQ C +Q AL+ +PGA + IP+ + +P LRF+ D P
Sbjct: 146 LITPGFLQDPWCKYQMLQALTEAPGA-EGCTIPLLSGLSRAAYPPELRFMYYVDGRGP 202
>gi|4504661 interleukin 1 receptor accessory protein isoform 1 [Homo
sapiens]
Length = 570
Score = 50.4 bits (119), Expect = 2e-06
Identities = 41/145 (28%), Positives = 69/145 (47%), Gaps = 11/145 (7%)
Query: 172 ERFDAFICYCPS--DIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRC 229
+ +D ++ Y + + +FV +R + + + KLC+ DRD LPG V I+K
Sbjct: 403 KEYDIYVSYARNAEEEEFVLLTLRGVLENEFGYKLCIFDRDSLPGGIVTDETLSFIQK-S 461
Query: 230 RRMVVVVSDDY-LQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMK----KEFPSILRFI 284
RR++VV+S +Y LQ + + K L +I ++YKA+K KE +
Sbjct: 462 RRLLVVLSPNYVLQGTQALLELKAGLENMASRGNINVILVQYKAVKETKVKELKRAKTVL 521
Query: 285 TVCDYTNPCTK---SWFWTRLAKAL 306
TV + +K FW +L A+
Sbjct: 522 TVIKWKGEKSKYPQGRFWKQLQVAM 546
>gi|4504655 interleukin 18 receptor 1 precursor [Homo sapiens]
Length = 541
Score = 47.0 bits (110), Expect = 2e-05
Identities = 35/117 (29%), Positives = 59/117 (50%), Gaps = 16/117 (13%)
Query: 174 FDAFICYCPS-------DIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIE 226
+DAF+ Y + F E++ ++ + ++ KLC+ +RDV+PG V LIE
Sbjct: 375 YDAFVSYLKECRPENGEEHTFAVEILPRVLEKHFGYKLCIFERDVVPGGAVVDEIHSLIE 434
Query: 227 KRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKYKAMKKEFPSILRF 283
K RR+++V+S Y+ S E ++ L G H+ L+ K K + EF + F
Sbjct: 435 K-SRRLIIVLSKSYM-SNEVRYE------LESGLHE-ALVERKIKIILIEFTPVTDF 482
>gi|205277451 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 44.7 bits (104), Expect = 1e-04
Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 7/77 (9%)
Query: 174 FDAFICY--CPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIE--KRC 229
+DA++ Y CP D +FV +++ + KL + DRD+LP +++L+ RC
Sbjct: 165 YDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRA---EPSADLLVNLSRC 221
Query: 230 RRMVVVVSDDYLQSKEC 246
RR++VV+SD +L C
Sbjct: 222 RRLIVVLSDAFLSRAWC 238
>gi|205277449 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 44.7 bits (104), Expect = 1e-04
Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 7/77 (9%)
Query: 174 FDAFICY--CPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIE--KRC 229
+DA++ Y CP D +FV +++ + KL + DRD+LP +++L+ RC
Sbjct: 165 YDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRA---EPSADLLVNLSRC 221
Query: 230 RRMVVVVSDDYLQSKEC 246
RR++VV+SD +L C
Sbjct: 222 RRLIVVLSDAFLSRAWC 238
>gi|205277445 single Ig IL-1R-related molecule [Homo sapiens]
Length = 410
Score = 44.7 bits (104), Expect = 1e-04
Identities = 26/77 (33%), Positives = 44/77 (57%), Gaps = 7/77 (9%)
Query: 174 FDAFICY--CPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIE--KRC 229
+DA++ Y CP D +FV +++ + KL + DRD+LP +++L+ RC
Sbjct: 165 YDAYVSYSDCPEDRKFVNFILKPQLERRRGYKLFLDDRDLLPRA---EPSADLLVNLSRC 221
Query: 230 RRMVVVVSDDYLQSKEC 246
RR++VV+SD +L C
Sbjct: 222 RRLIVVLSDAFLSRAWC 238
>gi|20143971 toll-like receptor 6 [Homo sapiens]
Length = 796
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/146 (25%), Positives = 72/146 (49%), Gaps = 13/146 (8%)
Query: 173 RFDAFICYCPSDIQFVQ-EMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRR 231
+F AFI Y D +V+ E++ LE+ + +++C+ +R+ +PG + IEK +
Sbjct: 641 QFHAFISYSEHDSAWVKSELVPYLEKED--IQICLHERNFVPGKSIVENIINCIEK-SYK 697
Query: 232 MVVVVSDDYLQSKECDFQTKFALS--LSPGAHQKRLI---PIKYKAMKKEFPSILRFITV 286
+ V+S +++QS+ C ++ FA G++ LI PI ++ ++ + +T
Sbjct: 698 SIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNNLILILLEPIPQNSIPNKYHKLKALMTQ 757
Query: 287 CDYTN-PCTKS---WFWTRLAKALSL 308
Y P KS FW + A ++
Sbjct: 758 RTYLQWPKEKSKRGLFWANIRAAFNM 783
>gi|7706093 toll-like receptor 7 [Homo sapiens]
Length = 1049
Score = 40.0 bits (92), Expect = 0.003
Identities = 41/147 (27%), Positives = 72/147 (48%), Gaps = 16/147 (10%)
Query: 174 FDAFICYCPSDIQFVQ----EMIRQLEQTNYR-LKLCVSDRDVLPGTCVWSIASELIEKR 228
+DAFI Y D + E++ +LE + LC+ +RD LPG V S+ I+
Sbjct: 891 YDAFIVYDTKDPAVTEWVLAELVAKLEDPREKHFNLCLEERDWLPGQPVLENLSQSIQ-L 949
Query: 229 CRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQK----RLIPIKYKAMKKEFPSILRFI 284
++ V V++D Y +++ +F+ F LS +K LI ++ K +F + + +
Sbjct: 950 SKKTVFVMTDKYAKTE--NFKIAFYLSHQRLMDEKVDVIILIFLEKPFQKSKFLQLRKRL 1007
Query: 285 ---TVCDY-TNPCTKSWFWTRLAKALS 307
+V ++ TNP +FW L AL+
Sbjct: 1008 CGSSVLEWPTNPQAHPYFWQCLKNALA 1034
>gi|16751843 toll-like receptor 5 [Homo sapiens]
Length = 858
Score = 40.0 bits (92), Expect = 0.003
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 7/89 (7%)
Query: 164 DDPLGHMPE--RFDAFICYCPSDIQFVQEMIRQLEQTNY----RLKLCVSDRDVLPGTCV 217
D P G P+ ++DA++C+ D +VQ + + T Y R LC +RD +PG
Sbjct: 681 DHPQGTEPDMYKYDAYLCFSSKDFTWVQNALLKHLDTQYSDQNRFNLCFEERDFVPGENR 740
Query: 218 WSIASELIEKRCRRMVVVVSDDYLQSKEC 246
+ + I R++V +VS +L+ C
Sbjct: 741 IANIQDAI-WNSRKIVCLVSRHFLRDGWC 768
>gi|16933525 unc5C [Homo sapiens]
Length = 931
Score = 39.3 bits (90), Expect = 0.004
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 8/92 (8%)
Query: 29 STSSLPLAALNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLL 88
S S+PL +R++L L+ DW LA +++ + + T++ PTG +L
Sbjct: 840 SAFSIPLP-----IRQKLCSSLDAPQTRGHDWRMLAHKLNLDRY-LNYFATKSSPTGVIL 893
Query: 89 DAWQGR--PGASVGRLLELLTKLGRDDVLLEL 118
D W+ + P ++ L +L ++GR + ++ L
Sbjct: 894 DLWEAQNFPDGNLSMLAAVLEEMGRHETVVSL 925
>gi|11225607 interleukin 1 receptor accessory protein-like 2 [Homo
sapiens]
Length = 686
Score = 38.5 bits (88), Expect = 0.008
Identities = 18/67 (26%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 175 DAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVV 234
D C P + QF E++ + + +Y KL + +RD++P + +E + RR+++
Sbjct: 414 DTLDCDNPEEEQFALEVLPDVLEKHYGYKLFIPERDLIPSGTYMEDLTRYVE-QSRRLII 472
Query: 235 VVSDDYL 241
V++ DY+
Sbjct: 473 VLTPDYI 479
>gi|41350337 toll-like receptor 1 [Homo sapiens]
Length = 786
Score = 38.1 bits (87), Expect = 0.010
Identities = 24/82 (29%), Positives = 47/82 (57%), Gaps = 4/82 (4%)
Query: 173 RFDAFICYCPSDIQFVQ-EMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRR 231
+F AFI Y D +V+ E++ LE+ +++C+ +R+ +PG + IEK +
Sbjct: 636 QFHAFISYSGHDSFWVKNELLPNLEKEG--MQICLHERNFVPGKSIVENIITCIEK-SYK 692
Query: 232 MVVVVSDDYLQSKECDFQTKFA 253
+ V+S +++QS+ C ++ FA
Sbjct: 693 SIFVLSPNFVQSEWCHYELYFA 714
>gi|4504657 interleukin 18 receptor accessory protein precursor
[Homo sapiens]
Length = 599
Score = 37.4 bits (85), Expect = 0.017
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 15/119 (12%)
Query: 164 DDPLGHMPERFDAFICYCP------------SDIQFVQEMIRQLEQTNYRLKLCVSDRDV 211
D LG + FDAF+ Y S+ + + + Y LC+ +RDV
Sbjct: 399 DQTLGDKKD-FDAFVSYAKWSSFPSEATSSLSEEHLALSLFPDVLENKYGYSLCLLERDV 457
Query: 212 LPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKECDFQTKFALSLSPGAHQKRLIPIKY 270
PG V++ I KR RR + ++S +Y+ F+ + A++L+ +LI IK+
Sbjct: 458 APGG-VYAEDIVSIIKRSRRGIFILSPNYVNGPSI-FELQAAVNLALDDQTLKLILIKF 514
>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
Length = 1863
Score = 37.4 bits (85), Expect = 0.017
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 10/82 (12%)
Query: 41 RVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQ-----ADPTGRLLDAWQGRP 95
R+ RL+ + + WT LA E+DF +I Q+ + D + LL W R
Sbjct: 1474 RIEERLAY---IADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERD 1530
Query: 96 G--ASVGRLLELLTKLGRDDVL 115
G A+ L+E LTK+ R D++
Sbjct: 1531 GKHATDTNLVECLTKINRMDIV 1552
>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
Length = 1872
Score = 37.4 bits (85), Expect = 0.017
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 10/82 (12%)
Query: 41 RVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQ-----ADPTGRLLDAWQGRP 95
R+ RL+ + + WT LA E+DF +I Q+ + D + LL W R
Sbjct: 1483 RIEERLAY---IADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERD 1539
Query: 96 G--ASVGRLLELLTKLGRDDVL 115
G A+ L+E LTK+ R D++
Sbjct: 1540 GKHATDTNLVECLTKINRMDIV 1561
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 37.4 bits (85), Expect = 0.017
Identities = 26/82 (31%), Positives = 40/82 (48%), Gaps = 10/82 (12%)
Query: 41 RVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQ-----ADPTGRLLDAWQGRP 95
R+ RL+ + + WT LA E+DF +I Q+ + D + LL W R
Sbjct: 3568 RIEERLAY---IADHLGFSWTELARELDFTEEQIHQIRIENPNSLQDQSHALLKYWLERD 3624
Query: 96 G--ASVGRLLELLTKLGRDDVL 115
G A+ L+E LTK+ R D++
Sbjct: 3625 GKHATDTNLVECLTKINRMDIV 3646
>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
Length = 1430
Score = 36.6 bits (83), Expect = 0.029
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 7/83 (8%)
Query: 38 LNMRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQA-------DPTGRLLDA 90
LN+ RR+LS L+ + DW LA + L + + P LL
Sbjct: 1305 LNLLTRRKLSRLLDPPDPLGKDWCLLAMNLGLPDLVAKYNTSNGAPKDFLPSPLHALLRE 1364
Query: 91 WQGRPGASVGRLLELLTKLGRDD 113
W P ++VG L+ L +LGR D
Sbjct: 1365 WTTYPESTVGTLMSKLRELGRRD 1387
>gi|32261318 unc-5 homolog B [Homo sapiens]
Length = 945
Score = 36.2 bits (82), Expect = 0.038
Identities = 20/89 (22%), Positives = 45/89 (50%), Gaps = 5/89 (5%)
Query: 40 MRVRRRLSLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQADPTGRLLDAWQG--RPGA 97
+ +R+++ L+ DW LA+++ + + T+A PTG +LD W+ +
Sbjct: 860 LSIRQKICNSLDAPNSRGNDWRMLAQKLSMDRY-LNYFATKASPTGVILDLWEALQQDDG 918
Query: 98 SVGRLLELLTKLGRDDVLLELGPSIEEDC 126
+ L L ++G+ ++L+ + + + DC
Sbjct: 919 DLNSLASALEEMGKSEMLVAV--ATDGDC 945
>gi|61742786 leucine rich repeat and death domain containing protein
isoform 3 [Homo sapiens]
Length = 893
Score = 35.0 bits (79), Expect = 0.084
Identities = 29/115 (25%), Positives = 57/115 (49%), Gaps = 16/115 (13%)
Query: 47 SLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQA-----DPTGRLLDAWQ----GRPGA 97
S L+V ++ DW A+A + Y E++++ + + +L +W G+PGA
Sbjct: 773 SNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAERQAGQPGA 832
Query: 98 SVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVP 152
VG L++ L + R DV E+ +E +KY +++ + + +A D ++P
Sbjct: 833 -VGLLVQALEQSDRQDVAEEVRAVLELGRRKY------QDSIRRMGLAPKDPALP 880
>gi|61742784 leucine rich repeat and death domain containing protein
isoform 1 [Homo sapiens]
Length = 910
Score = 35.0 bits (79), Expect = 0.084
Identities = 29/115 (25%), Positives = 57/115 (49%), Gaps = 16/115 (13%)
Query: 47 SLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQA-----DPTGRLLDAWQ----GRPGA 97
S L+V ++ DW A+A + Y E++++ + + +L +W G+PGA
Sbjct: 790 SNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAERQAGQPGA 849
Query: 98 SVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVP 152
VG L++ L + R DV E+ +E +KY +++ + + +A D ++P
Sbjct: 850 -VGLLVQALEQSDRQDVAEEVRAVLELGRRKY------QDSIRRMGLAPKDPALP 897
>gi|61742782 leucine rich repeat and death domain containing protein
isoform 2 [Homo sapiens]
Length = 753
Score = 35.0 bits (79), Expect = 0.084
Identities = 29/115 (25%), Positives = 57/115 (49%), Gaps = 16/115 (13%)
Query: 47 SLFLNVRTQVAADWTALAEEMDFEYLEIRQLETQA-----DPTGRLLDAWQ----GRPGA 97
S L+V ++ DW A+A + Y E++++ + + +L +W G+PGA
Sbjct: 633 SNLLSVAGRLGLDWPAVALHLGVSYREVQRIRHEFRDDLDEQIRHMLFSWAERQAGQPGA 692
Query: 98 SVGRLLELLTKLGRDDVLLELGPSIEEDCQKYILKQQQEEAEKPLQVAAVDSSVP 152
VG L++ L + R DV E+ +E +KY +++ + + +A D ++P
Sbjct: 693 -VGLLVQALEQSDRQDVAEEVRAVLELGRRKY------QDSIRRMGLAPKDPALP 740
>gi|31442420 shroom family member 1 [Homo sapiens]
Length = 847
Score = 34.7 bits (78), Expect = 0.11
Identities = 26/67 (38%), Positives = 34/67 (50%), Gaps = 8/67 (11%)
Query: 14 MAAGGPGAGSAAPVSSTSSLPLAALNMRVRRRLSLFL------NVRTQVAADWTALAEEM 67
M A GPG A+P SSTSSL L L+MR S F RTQ + T L +
Sbjct: 1 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQ--SPGTDLLPYL 58
Query: 68 DFEYLEI 74
D++Y+ +
Sbjct: 59 DWDYVRV 65
>gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [Homo
sapiens]
Length = 556
Score = 33.9 bits (76), Expect = 0.19
Identities = 21/89 (23%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Query: 187 FVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMVVVVSDDYLQSKEC 246
FV +++ + + LC+ RD+LPG V + A E ++ RR + +++ +KE
Sbjct: 400 FVHQILPDVLENKCGYTLCIYGRDMLPGEDVVT-AVETNIRKSRRHIFILTPQITHNKEF 458
Query: 247 DFQTKFALSLSPGAHQKRLIPIKYKAMKK 275
++ + AL + + ++I I+ +A+ +
Sbjct: 459 AYEQEVALHCALIQNDAKVILIEMEALSE 487
>gi|169203406 PREDICTED: hypothetical protein [Homo sapiens]
Length = 145
Score = 32.3 bits (72), Expect = 0.55
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 7 EAPGPPAMAAGGPGAGSAAPVSSTSSLP 34
EAP A GPGAG+AAP + +SLP
Sbjct: 58 EAPAERGDGACGPGAGAAAPAPAAASLP 85
>gi|169202578 PREDICTED: hypothetical protein [Homo sapiens]
Length = 145
Score = 32.3 bits (72), Expect = 0.55
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 7 EAPGPPAMAAGGPGAGSAAPVSSTSSLP 34
EAP A GPGAG+AAP + +SLP
Sbjct: 58 EAPAERGDGACGPGAGAAAPAPAAASLP 85
>gi|4507531 toll-like receptor 3 [Homo sapiens]
Length = 904
Score = 32.0 bits (71), Expect = 0.71
Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 1/73 (1%)
Query: 174 FDAFICYCPSDIQFVQEMIRQLEQTNYRLKLCVSDRDVLPGTCVWSIASELIEKRCRRMV 233
+ A+I + D +V E +E+ + LK C+ +RD G I KR R+++
Sbjct: 756 YAAYIIHAYKDKDWVWEHFSSMEKEDQSLKFCLEERDFEAGVFELEAIVNSI-KRSRKII 814
Query: 234 VVVSDDYLQSKEC 246
V++ L+ C
Sbjct: 815 FVITHHLLKDPLC 827
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,479,861
Number of Sequences: 37866
Number of extensions: 535056
Number of successful extensions: 3134
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 3089
Number of HSP's gapped (non-prelim): 71
length of query: 309
length of database: 18,247,518
effective HSP length: 102
effective length of query: 207
effective length of database: 14,385,186
effective search space: 2977733502
effective search space used: 2977733502
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.