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Search of human proteins with 195947389
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
(888 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens] 1884 0.0
gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens] 1819 0.0
gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens] 1795 0.0
gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 ... 790 0.0
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ... 754 0.0
gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4 (p... 192 2e-48
gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5 (... 184 3e-46
gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [... 178 2e-44
gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7 [... 176 9e-44
gi|239755573 PREDICTED: similar to ectonucleotide pyrophosphatas... 73 1e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 54 8e-07
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 54 8e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 49 2e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 49 2e-05
gi|88853069 vitronectin precursor [Homo sapiens] 42 0.003
gi|5174623 placental protein 11 precursor [Homo sapiens] 41 0.006
gi|38045917 phosphatidylinositol glycan anchor biosynthesis, cla... 40 0.007
gi|23397648 phosphatidylinositol glycan anchor biosynthesis, cla... 40 0.007
gi|4557733 latent transforming growth factor beta binding protei... 40 0.013
gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens] 38 0.048
gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens] 38 0.048
gi|187608744 zinc finger protein 9 isoform 5 [Homo sapiens] 38 0.048
gi|123702038 keratin associated protein 5-9 [Homo sapiens] 38 0.048
gi|209969800 RPE-spondin [Homo sapiens] 36 0.14
gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens] 36 0.18
gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens] 36 0.18
gi|146229327 arylsulfatase A isoform b [Homo sapiens] 36 0.18
gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens] 36 0.18
gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens] 36 0.18
gi|187608732 zinc finger protein 9 isoform 2 [Homo sapiens] 35 0.24
>gi|195947389 autotaxin isoform 3 preproprotein [Homo sapiens]
Length = 888
Score = 1884 bits (4880), Expect = 0.0
Identities = 888/888 (100%), Positives = 888/888 (100%)
Query: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK
Sbjct: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
Query: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC
Sbjct: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
Query: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK
Sbjct: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
Query: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA
Sbjct: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
Query: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER
Sbjct: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
Query: 301 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360
PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH
Sbjct: 301 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360
Query: 361 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH 420
GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH
Sbjct: 361 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH 420
Query: 421 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK 480
FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK
Sbjct: 421 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK 480
Query: 481 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF 540
VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF
Sbjct: 481 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF 540
Query: 541 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEAETRKFR 600
RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEAETRKFR
Sbjct: 541 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEAETRKFR 600
Query: 601 GSRNENKENINGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT 660
GSRNENKENINGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT
Sbjct: 601 GSRNENKENINGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT 660
Query: 661 VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYD 720
VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYD
Sbjct: 661 VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYD 720
Query: 721 AFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ 780
AFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ
Sbjct: 721 AFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ 780
Query: 781 YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKW 840
YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKW
Sbjct: 781 YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKW 840
Query: 841 VEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 888
VEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI
Sbjct: 841 VEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 888
>gi|91823602 autotaxin isoform 2 preproprotein [Homo sapiens]
Length = 863
Score = 1819 bits (4711), Expect = 0.0
Identities = 863/888 (97%), Positives = 863/888 (97%), Gaps = 25/888 (2%)
Query: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK
Sbjct: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
Query: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC
Sbjct: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
Query: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK
Sbjct: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
Query: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA
Sbjct: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
Query: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER
Sbjct: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
Query: 301 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360
PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH
Sbjct: 301 PSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360
Query: 361 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH 420
GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH
Sbjct: 361 GMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQH 420
Query: 421 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK 480
FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK
Sbjct: 421 FKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNK 480
Query: 481 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF 540
VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF
Sbjct: 481 VNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTF 540
Query: 541 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEAETRKFR 600
RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTE
Sbjct: 541 RPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTE------- 593
Query: 601 GSRNENKENINGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT 660
ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT
Sbjct: 594 ------------------ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYT 635
Query: 661 VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYD 720
VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYD
Sbjct: 636 VSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYD 695
Query: 721 AFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ 780
AFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ
Sbjct: 696 AFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQ 755
Query: 781 YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKW 840
YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKW
Sbjct: 756 YVEGSSIPVPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKW 815
Query: 841 VEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 888
VEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI
Sbjct: 816 VEELMKMHTARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 863
>gi|91823274 autotaxin isoform 1 preproprotein [Homo sapiens]
Length = 915
Score = 1795 bits (4648), Expect = 0.0
Identities = 863/940 (91%), Positives = 863/940 (91%), Gaps = 77/940 (8%)
Query: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK
Sbjct: 1 MARRSSFQSCQIISLFTFAVGVNICLGFTAHRIKRAEGWEEGPPTVLSDSPWTNISGSCK 60
Query: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC
Sbjct: 61 GRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHC 120
Query: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK
Sbjct: 121 SEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRASYMK 180
Query: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA
Sbjct: 181 KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDA 240
Query: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER
Sbjct: 241 TFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHER 300
Query: 301 PSVYAFYSEQPDFSGHKYGPFGPE------------------------------------ 324
PSVYAFYSEQPDFSGHKYGPFGPE
Sbjct: 301 PSVYAFYSEQPDFSGHKYGPFGPEESSYGSPFTPAKRPKRKVAPKRRQERPVAPPKKRRR 360
Query: 325 ----------------MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 368
MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD
Sbjct: 361 KIHRMDHYAAETRQDKMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCD 420
Query: 369 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 428
RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH
Sbjct: 421 RTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQH 480
Query: 429 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 488
LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF
Sbjct: 481 LPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVF 540
Query: 489 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 548
VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV
Sbjct: 541 VGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEV 600
Query: 549 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTEAETRKFRGSRNENKE 608
TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTE
Sbjct: 601 TRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLDELNKRLHTKGSTE--------------- 645
Query: 609 NINGNFEPRKERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVS 668
ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVS
Sbjct: 646 ----------ERHLLYGRPAVLYRTRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVS 695
Query: 669 SVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMV 728
SVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMV
Sbjct: 696 SVPDHLTSCVRPDVRVSPSFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMV 755
Query: 729 PMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIP 788
PMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIP
Sbjct: 756 PMYPAFKRVWNYFQRVLVKKYASERNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIP 815
Query: 789 VPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMH 848
VPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMH
Sbjct: 816 VPTHYYSIITSCLDFTQPADKCDGPLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMH 875
Query: 849 TARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 888
TARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI
Sbjct: 876 TARVRDIEHLTSLDFFRKTSRSYPEILTLKTYLHTYESEI 915
>gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3
[Homo sapiens]
Length = 875
Score = 790 bits (2041), Expect = 0.0
Identities = 379/856 (44%), Positives = 542/856 (63%), Gaps = 56/856 (6%)
Query: 57 GSCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEEN 116
GSC+ +CF+ G +CRCD CK CC DF++ C+++ R W C K RCGE R E +
Sbjct: 52 GSCRKKCFDASFRGLENCRCDVACKDRGDCCWDFEDTCVESTRIWMCNKFRCGETRLEAS 111
Query: 117 ACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRA 176
C CS+DCL R DCC +Y+ VC+GE+ W++++C+ + ++CP GF PP+I+FS+DGFRA
Sbjct: 112 LCSCSDDCLQRKDCCADYKSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRA 171
Query: 177 SYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDP 236
Y+ +MPNI KL++CG HS YMR +YPTKTFPN YT+ TGLYPESHGI+ N+MYD
Sbjct: 172 EYLYTWDTLMPNINKLKTCGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDV 231
Query: 237 VFDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SV 278
+ F L +E+ N WW GQP+W+TA QG+KA T+FW +
Sbjct: 232 NLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNG 291
Query: 279 VIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQ 338
+P E RI T+L+WL LP ERP Y Y E+PD SGH GP + L+ +D G
Sbjct: 292 SVPFEERISTLLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGM 351
Query: 339 LMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFS 398
LM+GLKQ LH CVN+I + DHGM+ C++ E++++Y ++ + G RIR +
Sbjct: 352 LMEGLKQRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIR---A 408
Query: 399 NNAKYD-----PKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWH 453
+N +D + I+ NL+C+KPDQHFKPYL LPKRLHYA N RI+ +HL V+++W
Sbjct: 409 HNIPHDFFSFNSEEIVRNLSCRKPDQHFKPYLTPDLPKRLHYAKNVRIDKVHLFVDQQW- 467
Query: 454 VARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVM 513
L V K + C G+HG++N+ SM+ +F+ +G +FK KT+V PFENIE+YN+M
Sbjct: 468 -----LAVRSKSNTNC-GGGNHGYNNEFRSMEAIFLAHGPSFKEKTEVEPFENIEVYNLM 521
Query: 514 CDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKV 573
CDLL ++PAPNNGTHGSLNHLL+ + P+ EEV++ + G L C C +
Sbjct: 522 CDLLRIQPAPNNGTHGSLNHLLKVPFYEPSHAEEVSKFSVCGFANPLPTESLDCFC-PHL 580
Query: 574 EPKNKLDELNKRLHTKGSTEAETRKFRGSRNENKENINGNFEPRKERHLLYGRPAVLYR- 632
+ +L+++N+ L N +E I + +L +GRP VL +
Sbjct: 581 QNSTQLEQVNQML-----------------NLTQEEITATVKV----NLPFGRPRVLQKN 619
Query: 633 TRYDILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNC 692
+ +LYH ++ SG+ + MP+W+SYTV + + S +P + C+R DVRV PS SQ C
Sbjct: 620 VDHCLLYHREYVSGFGKAMRMPMWSSYTVPQLGDTSPLPPTVPDCLRADVRVPPSESQKC 679
Query: 693 LAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASE 752
Y DK +++GFL+PP + + +++YDA + +N+VPMY F+++W+YF VL+ K+A+E
Sbjct: 680 SFYLADKNITHGFLYPPASNRTSDSQYDALITSNLVPMYEEFRKMWDYFHSVLLIKHATE 739
Query: 753 RNGVNVISGPIFDYDYDGLHDTEDKIKQYVEGSSIPVPTHYYSIITSCLDFTQPADKCDG 812
RNGVNV+SGPIFDY+YDG D D+I +++ + +P+PTHY+ ++TSC + + + C G
Sbjct: 740 RNGVNVVSGPIFDYNYDGHFDAPDEITKHLANTDVPIPTHYFVVLTSCKNKSHTPENCPG 799
Query: 813 PLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYP 872
L V FI+PHRP N ESC + E+ WVEE H ARVRD+E LT LDF++ +
Sbjct: 800 WLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRDVELLTGLDFYQDKVQPVS 859
Query: 873 EILTLKTYLHTYESEI 888
EIL LKTYL T+E+ I
Sbjct: 860 EILQLKTYLPTFETTI 875
>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
[Homo sapiens]
Length = 925
Score = 754 bits (1947), Expect = 0.0
Identities = 379/855 (44%), Positives = 521/855 (60%), Gaps = 62/855 (7%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
SCKGRCFE +CRCD C +CC D+ E C++ W C K RCGE R +
Sbjct: 107 SCKGRCFERTFG---NCRCDAACVELGNCCLDYQETCIEPEHIWTCNKFRCGEKRLTRSL 163
Query: 118 CHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAECPAGFVRPPLIIFSVDGFRAS 177
C CS+DC +GDCC NY VC+GE WV++ CE I +CPAGF PP ++FS+DGFRA
Sbjct: 164 CACSDDCKDKGDCCINYSSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAE 223
Query: 178 YMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV 237
Y+ ++P I KL+ CGT++ MRPVYPTKTFPN Y++ TGLYPESHGI+ N MYDP
Sbjct: 224 YLHTWGGLLPVISKLKKCGTYTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPK 283
Query: 238 FDATFHLRGREKFNHRWWGGQPLWITATKQGVKAGTFFW------------------SVV 279
+A+F L+ +EKFN W+ G+P+W+TA QG+K+GTFFW +
Sbjct: 284 MNASFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGS 343
Query: 280 IPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQL 339
+P E RIL +LQWL LP ERP Y Y E+PD SGH YGP E+ L+ +D +VG L
Sbjct: 344 VPFEERILAVLQWLQLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGML 403
Query: 340 MDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSN 399
MDGLK+L LHRC+N+I + DHGME +C + +L+ YL +V +I ++ G R+R
Sbjct: 404 MDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVP 463
Query: 400 NAKY--DPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARK 457
+ Y + + I NL+C++P+QHFKPYLK LPKRLH+A + RIE + ++ +W +A
Sbjct: 464 DKYYSFNYEGIARNLSCREPNQHFKPYLKHFLPKRLHFAKSDRIEPLTFYLDPQWQLALN 523
Query: 458 PLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFENIELYNVMCDLL 517
P + +K G G HG DN ++MQ +FVGYG FK+ + FENIE+YN+MCDLL
Sbjct: 524 PSE--RKYCG----SGFHGSDNVFSNMQALFVGYGPGFKHGIEADTFENIEVYNLMCDLL 577
Query: 518 GLKPAPNNGTHGSLNHLLRTNTFRPTMPEEVTRPNYPGIMYLQSDFDLGCTCDDKVEPKN 577
L PAPNNGTHGSLNHLL+ + P P+EV P +LGC+C+ + P
Sbjct: 578 NLTPAPNNGTHGSLNHLLKNPVYTPKHPKEV-HPLVQCPFTRNPRDNLGCSCNPSILP-- 634
Query: 578 KLDELNKRLHTKGSTEAETRKFRGSRNENKENINGNFEPRKERHLLYGRPAVLYR-TRYD 636
+++ + + T AE + K L YGRP VL +
Sbjct: 635 -IEDFQTQFNL---TVAEEKII------------------KHETLPYGRPRVLQKENTIC 672
Query: 637 ILYHTDFESGYSEIFLMPLWTSYTVSKQAEVSSVPDHLTSCVRPDVRVSPSFSQNCLAYK 696
+L F SGYS+ LMPLWTSYTV + S+ + ++C+ D R+ S C YK
Sbjct: 673 LLSQHQFMSGYSQDILMPLWTSYTVDRNDSFST--EDFSNCLYQDFRIPLSPVHKCSFYK 730
Query: 697 NDKQMSYGFLFPPYLSSSPEAKY-DAFLVTNMVPMYPAFKRVWNYFQRVLVKKYASERNG 755
N+ ++SYGFL PP L+ + Y +A L TN+VPMY +F+ +W YF L++KYA ERNG
Sbjct: 731 NNTKVSYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFHDTLLRKYAEERNG 790
Query: 756 VNVISGPIFDYDYDGLHDTEDKIKQ---YVEGSSIPVPTHYYSIITSCLDFTQPADKCDG 812
VNV+SGP+FD+DYDG D+ + ++Q + I +PTH++ ++TSC D +Q C+
Sbjct: 791 VNVVSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCEN 850
Query: 813 PLSVSSFILPHRPDNEESCNSSEDESKWVEELMKMHTARVRDIEHLTSLDFFRKTSRSYP 872
L +FILPHR DN ESC + +S WVEEL+ +H AR+ D+EH+T L F+++
Sbjct: 851 -LDTLAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFYQQRKEPVS 909
Query: 873 EILTLKTYLHTYESE 887
+IL LKT+L T+ E
Sbjct: 910 DILKLKTHLPTFSQE 924
>gi|7662358 ectonucleotide pyrophosphatase/phosphodiesterase 4
(putative function) [Homo sapiens]
Length = 453
Score = 192 bits (487), Expect = 2e-48
Identities = 130/394 (32%), Positives = 188/394 (47%), Gaps = 45/394 (11%)
Query: 164 PPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYP 223
P L++ S DGFRA Y+K P+++ G +++ V+ TKTFPN Y++ TGLY
Sbjct: 26 PKLLLVSFDGFRADYLKNYE--FPHLQNFIKEGVLVEHVKNVFITKTFPNHYSIVTGLYE 83
Query: 224 ESHGIVGNSMYDPVFDATFHLRGREKFNHRWWG-GQPLWITATKQGVKAG---------- 272
ESHGIV NSMYD V H + WW P+W+T Q ++
Sbjct: 84 ESHGIVANSMYDAVTKK--HFSDSNDKDPFWWNEAVPIWVTNQLQENRSSAAAMWPGTDV 141
Query: 273 -------TFF--WSVVIPHERRILTILQWLTLPDHERPSVYA-FYSEQPDFSGHKYGPFG 322
++F ++ + E R+ I WL + P +A Y E+PD SGHKYGP
Sbjct: 142 PIHDTISSYFMNYNSSVSFEERLNNITMWLN--NSNPPVTFATLYWEEPDASGHKYGPED 199
Query: 323 PE-MTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVD 381
E M+ L++ID ++G L+ LK L L +NVI DHGM + DR L + + +
Sbjct: 200 KENMSRVLKKIDDLIGDLVQRLKMLGLWENLNVIITSDHGMTQCSQDRLINLDSCIDHSY 259
Query: 382 DITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRI 441
+ + I K + Y+ K H YLK+ +P R +Y +N RI
Sbjct: 260 YTLIDLSPVAAILPKINRTEVYNK--------LKNCSPHMNVYLKEDIPNRFYYQHNDRI 311
Query: 442 EDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKV 501
+ I L+ + W + V + S K GDHG+DN + SM +G F K
Sbjct: 312 QPIILVADEGWTI------VLNESSQKL---GDHGYDNSLPSMHPFLAAHGPAFHKGYKH 362
Query: 502 PPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLL 535
+++Y +MC +LGLKP PNNGT G LL
Sbjct: 363 STINIVDIYPMMCHILGLKPHPNNGTFGHTKCLL 396
>gi|11034849 ectonucleotide pyrophosphatase/phosphodiesterase 5
(putative function) [Homo sapiens]
Length = 477
Score = 184 bits (467), Expect = 3e-46
Identities = 117/391 (29%), Positives = 188/391 (48%), Gaps = 38/391 (9%)
Query: 166 LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPES 225
+++ S DGFR Y+ K P+ + G H + V+ TKT+PN YTL TGL+ E+
Sbjct: 30 VLLVSFDGFRWDYLYKVPT--PHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGLFAEN 87
Query: 226 HGIVGNSMYDPVFDATFHLRGREKFNHRWW-GGQPLWITATKQGVKAGTFFW-------- 276
HGIV N M+DP+ + +F L ++ ++W P+WIT + G +G W
Sbjct: 88 HGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTDVKIH 147
Query: 277 ----------SVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMT 326
+ + E R+ I++W T E ++ Y E PD GH GP P M
Sbjct: 148 KRFPTHYMPYNESVSFEDRVAKIIEWFT--SKEPINLGLLYWEDPDDMGHHLGPDSPLMG 205
Query: 327 NPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLV 386
+ +IDK +G L+ LK+ KL +N+I DHGM + +R L YL + D TL+
Sbjct: 206 PVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYL-DKDHYTLI 264
Query: 387 PGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHL 446
+ + + K+D + LT P + Y K+ +P+R HY N RI+ I
Sbjct: 265 DQS--PVAAILPKEGKFD--EVYEALTHAHP--NLTVYKKEDVPERWHYKYNSRIQPIIA 318
Query: 447 LVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPPFEN 506
+ + WH+ + D F G+HG+DN + M +F+ +G F+ +
Sbjct: 319 VADEGWHILQNKSD--------DFLLGNHGYDNALADMHPIFLAHGPAFRKNFSKEAMNS 370
Query: 507 IELYNVMCDLLGLKPAPNNGTHGSLNHLLRT 537
+LY ++C LL + P+NG+ ++ LL +
Sbjct: 371 TDLYPLLCHLLNITAMPHNGSFWNVQDLLNS 401
>gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6
[Homo sapiens]
Length = 440
Score = 178 bits (451), Expect = 2e-44
Identities = 115/414 (27%), Positives = 209/414 (50%), Gaps = 41/414 (9%)
Query: 163 RPPLIIFSVDGFRASYMK-KGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGL 221
R L++F +DGFR+ Y+ + + +P +++ S G Y+ P +P+ ++PN YTL TG
Sbjct: 23 RRKLLVFLLDGFRSDYISDEALESLPGFKEIVSRGVKVDYLTPDFPSLSYPNYYTLMTGR 82
Query: 222 YPESHGIVGNSMYDPVFDATFHLR-GREKFNHRWWGG-QPLWITATKQGVKAGTFFWSVV 279
+ E H ++GN M+DP + +F + ++ WW G +PLW+T TK K ++W
Sbjct: 83 HCEVHQMIGNYMWDPTTNKSFDIGVNKDSLMPLWWNGSEPLWVTLTKAKRKVYMYYWPGC 142
Query: 280 IPHERRILTI-----LQWLTLPDH----------------ERPSVYAFYSEQPDFSGHKY 318
E IL + L++ +P R + A Y E+ D GH Y
Sbjct: 143 ---EVEILGVRPTYCLEYKNVPTDINFANAVSDALDSFKSGRADLAAIYHERIDVEGHHY 199
Query: 319 GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDVT-CDRTEFLSNYL 377
GP P+ + L+ +D ++ + +++ L +NVI DHGM D+ D+ L+ Y+
Sbjct: 200 GPASPQRKDALKAVDTVLKYMTKWIQERGLQDRLNVIIFSDHGMTDIFWMDKVIELNKYI 259
Query: 378 TNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYAN 437
+ ++D+ V G + S + K+ I L+ +H Y K+ +P R +Y
Sbjct: 260 S-LNDLQQVKDR-GPVVSLWPAPGKHSE--IYNKLSTV---EHMTVYEKEAIPSRFYYKK 312
Query: 438 NRRIEDIHLLVERRWHVA--RKPLDVYKKPSGKC--FFQGDHGFDNKVNSMQTVFVGYGS 493
+ + + L+ + W + R+ L + +G+ + +G HG+DN++ M+ +F+ +G
Sbjct: 313 GKFVSPLTLVADEGWFITENREMLPFWMNSTGRREGWQRGWHGYDNELMDMRGIFLAFGP 372
Query: 494 TFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLL--RTNTFRPTMP 545
FK + P ++++YNVMC+++G+ P PNNG+ + +L R +T P P
Sbjct: 373 DFKSNFRAAPIRSVDVYNVMCNVVGITPLPNNGSWSRVMCMLKGRASTAPPVWP 426
>gi|45545421 ectonucleotide pyrophosphatase/phosphodiesterase 7
[Homo sapiens]
Length = 458
Score = 176 bits (446), Expect = 9e-44
Identities = 130/416 (31%), Positives = 197/416 (47%), Gaps = 67/416 (16%)
Query: 166 LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLYPES 225
L++ S DGFR +Y + PN++ + G + YM P + T T P +TL TG Y E+
Sbjct: 33 LLLVSFDGFRWNYDQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIEN 90
Query: 226 HGIVGNSMYDPV------FDATFHLRGREKFNHRWW--GGQPLWITATKQGVKAGTFFW- 276
HG+V N Y+ + AT ++ RWW G P+WITA +QG++AG+FF+
Sbjct: 91 HGVVHNMYYNTTSKVKLPYHATLGIQ-------RWWDNGSVPIWITAQRQGLRAGSFFYP 143
Query: 277 -------SVVIPHERR----------------ILTILQWLTLPDHERPSVYAFYSEQPDF 313
V + R+ I T++ W T D + + Y +PD
Sbjct: 144 GGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMAWFTEEDLD---LVTLYFGEPDS 200
Query: 314 SGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGMEDV---TCDRT 370
+GH+YGP PE +R++D+ VG L + + + L +N+I DHGM V D
Sbjct: 201 TGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKRAGDLV 260
Query: 371 EF--LSNYLTNVDDITLVP-GTLGRIRSKFSNNAK-YDPKAIIANLTCKKPDQHFKPYLK 426
EF N+ + L+ G G + K K YD L P H Y K
Sbjct: 261 EFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDA------LKDAHPKLHV--YKK 312
Query: 427 QHLPKRLHYANNRRIEDIHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKVNSMQT 486
+ P+ HYANN R+ + L+ +V ++V F G+HGFDNK M+T
Sbjct: 313 EAFPEAFHYANNPRVTPL-LMYSDLGYVIHGRINVQ-------FNNGEHGFDNKDMDMKT 364
Query: 487 VFVGYGSTFKYKTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRP 542
+F G +F+ +V PFE++ +Y +MC LLG+ P N+G +L +L T + P
Sbjct: 365 IFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALP 420
>gi|239755573 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 (putative function)
[Homo sapiens]
Length = 661
Score = 72.8 bits (177), Expect = 1e-12
Identities = 64/264 (24%), Positives = 103/264 (39%), Gaps = 36/264 (13%)
Query: 288 TILQWLTLPDHERPSVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLK 347
T++ T D + Y QPD GH++ P ++++D+ + L+ ++
Sbjct: 269 TVMNCFTKEDFD---FVTLYYRQPDNVGHRFKPEAENRKLMIQQLDRTIWYLVGATEKHS 325
Query: 348 LHRCVNVIFVGDHGMEDVTCDRTE---FLSNYLTNVD----DITLVPGTLGRIRSKFSNN 400
L + VI DHGM V LSNY+ D DI G +
Sbjct: 326 L-QSPQVIITXDHGMMTVKKRPNVNKIXLSNYIKFRDWVKFDIVGYGGFGLPLPKLGQEE 384
Query: 401 AKYDPKAIIANLTCKKPDQHFKPYLKQHLPKRLHYANNRRIEDIHLLVERRWHVARKPLD 460
A Y K H Y K+ P+ H A + R+ I + + +
Sbjct: 385 ALYQ--------ALKNAHPHLHIYKKEEFPEHFHLAKHDRVLPIVMYANSSYRYLDSSMR 436
Query: 461 VYKK----PSGK-------------CFFQGDHGFDNKVNSMQTVFVGYGSTFKYKTKVPP 503
+ + P+ + CF +G HGFDN + M+T+F +G FK
Sbjct: 437 TFNETRTFPTDQPDSLREQDARIIMCFNKGSHGFDNVLMDMKTIFRDFGPDFKKNGLAET 496
Query: 504 FENIELYNVMCDLLGLKPAPNNGT 527
F +I +Y +C LLG+ P +NG+
Sbjct: 497 FNSIHIYPFVCKLLGVXPQTHNGS 520
Score = 40.4 bits (93), Expect = 0.007
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 18/129 (13%)
Query: 154 AAECPAGFVRPP-------LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVY 206
A CPAG PP L++ S GFR + PN++ L G + Y+ P
Sbjct: 10 AIACPAGRPPPPREEEHSQLLLISFQGFRWDXDQDVDT--PNMDHLAGEGVKAKYLMPPL 67
Query: 207 PTKTFPNLYTLATG--LYPESHGIVGNSMYDP--VFDATFHLRGREK--FNHRWWGGQPL 260
T T P +T G L+ H ++ N M++ +++ +F ++ ++R L
Sbjct: 68 VTMTSPFHFTAMPGKLLWVRDHXVIHNMMFNTEMLWNCSFKTTQKKTQCXDNRVLS---L 124
Query: 261 WITATKQGV 269
WITA +QG+
Sbjct: 125 WITAQRQGL 133
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 53.5 bits (127), Expect = 8e-07
Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 5/81 (6%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
SC GRC E + C CD C+ Y CC DF +C K RC E
Sbjct: 29 SCAGRCGE-GYSRDATCNCDYNCQHYMECCPDFKRVCTAEL----SCKGRCFESFERGRE 83
Query: 118 CHCSEDCLARGDCCTNYQVVC 138
C C C CC +Y+ C
Sbjct: 84 CDCDAQCKKYDKCCPDYESFC 104
Score = 34.3 bits (77), Expect = 0.53
Identities = 12/35 (34%), Positives = 20/35 (57%)
Query: 107 RCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGE 141
RCGE + + C+C +C +CC +++ VC E
Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAE 67
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 53.5 bits (127), Expect = 8e-07
Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 5/81 (6%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
SC GRC E + C CD C+ Y CC DF +C K RC E
Sbjct: 29 SCAGRCGE-GYSRDATCNCDYNCQHYMECCPDFKRVCTAEL----SCKGRCFESFERGRE 83
Query: 118 CHCSEDCLARGDCCTNYQVVC 138
C C C CC +Y+ C
Sbjct: 84 CDCDAQCKKYDKCCPDYESFC 104
Score = 34.3 bits (77), Expect = 0.53
Identities = 12/35 (34%), Positives = 20/35 (57%)
Query: 107 RCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGE 141
RCGE + + C+C +C +CC +++ VC E
Sbjct: 33 RCGEGYSRDATCNCDYNCQHYMECCPDFKRVCTAE 67
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 49.3 bits (116), Expect = 2e-05
Identities = 20/37 (54%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
SCKGRCFE E G +C CD CK Y CC D++ C
Sbjct: 28 SCKGRCFESFERGR-ECDCDAQCKKYDKCCPDYESFC 63
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 49.3 bits (116), Expect = 2e-05
Identities = 20/37 (54%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
SCKGRCFE E G +C CD CK Y CC D++ C
Sbjct: 28 SCKGRCFESFERGR-ECDCDAQCKKYDKCCPDYESFC 63
>gi|88853069 vitronectin precursor [Homo sapiens]
Length = 478
Score = 41.6 bits (96), Expect = 0.003
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 3/54 (5%)
Query: 43 PPTVLSDSPWTNISG--SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
P +L+ W ++ SCKGRC E C+CD LC Y SCC D+ C
Sbjct: 6 PLLILALLAWVALADQESCKGRCTEGFNVDKK-CQCDELCSYYQSCCTDYTAEC 58
Score = 37.4 bits (85), Expect = 0.062
Identities = 16/38 (42%), Positives = 18/38 (47%)
Query: 102 ECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
E K RC E N + C C E C CCT+Y CK
Sbjct: 22 ESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECK 59
>gi|5174623 placental protein 11 precursor [Homo sapiens]
Length = 369
Score = 40.8 bits (94), Expect = 0.006
Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 1/37 (2%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELC 94
SC+GRC+E + C C+ C+ + +CC DF+ LC
Sbjct: 48 SCQGRCYEAFDKHH-QCHCNARCQEFGNCCKDFESLC 83
Score = 35.8 bits (81), Expect = 0.18
Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 107 RCGEVRNEENACHCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAE 156
RC E ++ + CHC+ C G+CC +++ +C H V + I E
Sbjct: 52 RCYEAFDKHHQCHCNARCQEFGNCCKDFESLC--SDHEVSHSSDAITKEE 99
>gi|38045917 phosphatidylinositol glycan anchor biosynthesis, class
O isoform 2 [Homo sapiens]
Length = 672
Score = 40.4 bits (93), Expect = 0.007
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 5/51 (9%)
Query: 312 DFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362
D GHK+GP PEM L ++D+++ L++ L+ L ++ GDHGM
Sbjct: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHGM 280
>gi|23397648 phosphatidylinositol glycan anchor biosynthesis, class
O isoform 1 [Homo sapiens]
Length = 1089
Score = 40.4 bits (93), Expect = 0.007
Identities = 19/51 (37%), Positives = 30/51 (58%), Gaps = 5/51 (9%)
Query: 312 DFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362
D GHK+GP PEM L ++D+++ L++ L+ L ++ GDHGM
Sbjct: 235 DHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTL-----LVVAGDHGM 280
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 39.7 bits (91), Expect = 0.013
Identities = 41/170 (24%), Positives = 61/170 (35%), Gaps = 53/170 (31%)
Query: 44 PTVLSDSPWTNISGSC------------KGRCFELQEAGPP----DCRCDNLCKSYT--- 84
P V S TN GS KG C ++ E P D RC N SYT
Sbjct: 937 PGVCSGGQCTNTEGSYHCECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLA 996
Query: 85 ---------SCCHDFDEL----------CLKTARGWECTKDRCGEVRNEENACHCSEDCL 125
C D +E C + C+ ++ EV ++E C ++C
Sbjct: 997 CEEGYRGQSGSCVDVNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECA 1056
Query: 126 ARGDCCTNYQVVCKG--------ESHWVDDD---CEEIKAAE----CPAG 160
+R C T + +G +WV++D CE++ CP+G
Sbjct: 1057 SRASCPTGLCLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSG 1106
>gi|169217819 PREDICTED: similar to hCG1793095 [Homo sapiens]
Length = 167
Score = 37.7 bits (86), Expect = 0.048
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 163 RPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLY 222
R L++ S D FR +Y + PN++ + G + YM P + T T P +TL TG Y
Sbjct: 30 RNKLLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87
>gi|239756564 PREDICTED: similar to hCG1793095 [Homo sapiens]
Length = 98
Score = 37.7 bits (86), Expect = 0.048
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 163 RPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYMRPVYPTKTFPNLYTLATGLY 222
R L++ S D FR +Y + PN++ + G + YM P + T T P +TL TG Y
Sbjct: 30 RNKLLLVSFDSFRWNYEQDVDT--PNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGEY 87
>gi|187608744 zinc finger protein 9 isoform 5 [Homo sapiens]
Length = 171
Score = 37.7 bits (86), Expect = 0.048
Identities = 29/108 (26%), Positives = 38/108 (35%), Gaps = 15/108 (13%)
Query: 60 KGRCFELQEAGPPDC--RCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
+GR F+ + PD RC C DE C RG KD C E + E
Sbjct: 32 RGRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDEACYNCGRGGHIAKD-CKEPKREREQ 90
Query: 118 C--------HCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAEC 157
C H + DC D + GE + DC ++K C
Sbjct: 91 CCYNCGKPGHLARDC----DHADEQKCYSCGEFGHIQKDCTKVKCYRC 134
>gi|123702038 keratin associated protein 5-9 [Homo sapiens]
Length = 169
Score = 37.7 bits (86), Expect = 0.048
Identities = 23/89 (25%), Positives = 32/89 (35%), Gaps = 8/89 (8%)
Query: 58 SCKGRCFELQEAGPPDCRCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENA 117
SC C G C+C + CK Y S C C + RG C + C + +
Sbjct: 81 SCCKPCCCSSGCGSSCCQC-SCCKPYCSQCSCCKPCCSSSGRGSSCCQSSCCKPCCSSSG 139
Query: 118 C-------HCSEDCLARGDCCTNYQVVCK 139
C C + C ++ CC CK
Sbjct: 140 CGSSCCQSSCCKPCCSQSRCCVPVCYQCK 168
>gi|209969800 RPE-spondin [Homo sapiens]
Length = 264
Score = 36.2 bits (82), Expect = 0.14
Identities = 19/68 (27%), Positives = 24/68 (35%), Gaps = 10/68 (14%)
Query: 80 CKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCSEDCLARGDCCTNYQVVCK 139
C CC D C ARGW + C C + C GDCC +Y C
Sbjct: 22 CAEAGRCCPGRDPACF--ARGWRLDR--------VYGTCFCDQACRFTGDCCFDYDRACP 71
Query: 140 GESHWVDD 147
+V +
Sbjct: 72 ARPCFVGE 79
>gi|146229331 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%)
Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360
++ P FSG + GPFG + L E+D VG LM + L L VIF D+
Sbjct: 227 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 282
Query: 361 GMEDVTCDR 369
G E + R
Sbjct: 283 GPETMRMSR 291
>gi|146229329 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%)
Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360
++ P FSG + GPFG + L E+D VG LM + L L VIF D+
Sbjct: 227 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 282
Query: 361 GMEDVTCDR 369
G E + R
Sbjct: 283 GPETMRMSR 291
>gi|146229327 arylsulfatase A isoform b [Homo sapiens]
Length = 423
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%)
Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360
++ P FSG + GPFG + L E+D VG LM + L L VIF D+
Sbjct: 143 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 198
Query: 361 GMEDVTCDR 369
G E + R
Sbjct: 199 GPETMRMSR 207
>gi|146229324 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%)
Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360
++ P FSG + GPFG + L E+D VG LM + L L VIF D+
Sbjct: 227 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 282
Query: 361 GMEDVTCDR 369
G E + R
Sbjct: 283 GPETMRMSR 291
>gi|6005990 arylsulfatase A isoform a precursor [Homo sapiens]
Length = 507
Score = 35.8 bits (81), Expect = 0.18
Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%)
Query: 307 YSEQPDFSGHKY------GPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDH 360
++ P FSG + GPFG + L E+D VG LM + L L VIF D+
Sbjct: 227 HTHYPQFSGQSFAERSGRGPFG----DSLMELDAAVGTLMTAIGDLGLLEETLVIFTADN 282
Query: 361 GMEDVTCDR 369
G E + R
Sbjct: 283 GPETMRMSR 291
>gi|187608732 zinc finger protein 9 isoform 2 [Homo sapiens]
Length = 178
Score = 35.4 bits (80), Expect = 0.24
Identities = 29/111 (26%), Positives = 37/111 (33%), Gaps = 15/111 (13%)
Query: 57 GSCKGRCFELQEAGPPDC--RCDNLCKSYTSCCHDFDELCLKTARGWECTKDRCGEVRNE 114
G R F+ + PD RC C DE C RG KD C E + E
Sbjct: 36 GFTSDRGFQFVSSSLPDICYRCGESGHLAKDCDLQEDEACYNCGRGGHIAKD-CKEPKRE 94
Query: 115 ENAC--------HCSEDCLARGDCCTNYQVVCKGESHWVDDDCEEIKAAEC 157
C H + DC D + GE + DC ++K C
Sbjct: 95 REQCCYNCGKPGHLARDC----DHADEQKCYSCGEFGHIQKDCTKVKCYRC 141
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,593,540
Number of Sequences: 37866
Number of extensions: 1916373
Number of successful extensions: 3992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 3870
Number of HSP's gapped (non-prelim): 125
length of query: 888
length of database: 18,247,518
effective HSP length: 111
effective length of query: 777
effective length of database: 14,044,392
effective search space: 10912492584
effective search space used: 10912492584
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.