Guide to the Human Genome
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Search of human proteins with 195927041

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
         (297 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]           599   e-171
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]             597   e-171
gi|16306492 cell division cycle 2 isoform 2 [Homo sapiens]            426   e-119
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]                   397   e-111
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]        395   e-110
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]                   331   4e-91
gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens]       326   1e-89
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]                   324   5e-89
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]        316   1e-86
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]          316   1e-86
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]         314   7e-86
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]         314   7e-86
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]         314   7e-86
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]                    273   1e-73
gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]                 257   1e-68
gi|4502741 cyclin-dependent kinase 6 [Homo sapiens]                   257   1e-68
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...   252   2e-67
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...   252   2e-67
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...   252   2e-67
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...   252   2e-67
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...   252   2e-67
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...   252   2e-67
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]                   251   5e-67
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]    251   7e-67
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]    251   7e-67
gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens]                   244   5e-65
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]        240   1e-63
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]      238   5e-63
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]    231   8e-61
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]    231   8e-61

>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
          Length = 297

 Score =  599 bits (1544), Expect = e-171
 Identities = 297/297 (100%), Positives = 297/297 (100%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
Sbjct: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
           PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
Sbjct: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
           SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
           YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240

Query: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
           FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297


>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
          Length = 297

 Score =  597 bits (1539), Expect = e-171
 Identities = 295/297 (99%), Positives = 296/297 (99%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
Sbjct: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
           PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH
Sbjct: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
           SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHE +TLWYRSPEVLLGSAR
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
           YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240

Query: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
           FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297


>gi|16306492 cell division cycle 2 isoform 2 [Homo sapiens]
          Length = 240

 Score =  426 bits (1095), Expect = e-119
 Identities = 227/297 (76%), Positives = 232/297 (78%), Gaps = 57/297 (19%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH
Sbjct: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
           PNIVSLQDVLMQDSRLYLIFEFLSMDLKK         Y+DS     Y+           
Sbjct: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKK---------YLDSIPPGQYM----------- 100

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
                            D   +K+                    +TLWYRSPEVLLGSAR
Sbjct: 101 -----------------DSSLVKV--------------------VTLWYRSPEVLLGSAR 123

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
           YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT
Sbjct: 124 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 183

Query: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
           FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
Sbjct: 184 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 240


>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
          Length = 305

 Score =  397 bits (1019), Expect = e-111
 Identities = 191/288 (66%), Positives = 232/288 (80%), Gaps = 1/288 (0%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           M+ + K+EKIGEGTYGVVYK +++ TGQ+VA+KKIRL+ E EGVPSTAIREISLLKEL+H
Sbjct: 1   MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
           PNIV L DV+  + +LYL+FEFLS DLKKY+DS P G  +   L+KSYL+Q+LQG+ FCH
Sbjct: 61  PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTP-GSELPLHLIKSYLFQLLQGVSFCH 119

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
           S RV+HRDLKPQNLLI++ G IKLADFGLARAFG+P+R YTHE +TLWYR+PE+LLGS  
Sbjct: 120 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF 179

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
           Y+T VDIWSIG IFAE+ T+K LF GDSEIDQLFRIFR LGTP+ + WP V  L DYK +
Sbjct: 180 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS 239

Query: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
           FPKW    L   V NL+  G DLL ++L YDP++RI+ K AL HPYF+
Sbjct: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287


>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
          Length = 298

 Score =  395 bits (1014), Expect = e-110
 Identities = 194/295 (65%), Positives = 234/295 (79%), Gaps = 3/295 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           ME++ K+EKIGEGTYGVVYK R+K TG+VVA+KKIRL++E EGVPSTAIREISLLKEL H
Sbjct: 1   MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLD-SIPPGQYMDSSLVKSYLYQILQGIVFC 119
           PNIV L DV+  +++LYL+FEFL  DLKK++D S   G  +   L+KSYL+Q+LQG+ FC
Sbjct: 61  PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFC 118

Query: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSA 179
           HS RVLHRDLKPQNLLI+ +G IKLADFGLARAFG+P+R YTHE +TLWYR+PE+LLG  
Sbjct: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCK 178

Query: 180 RYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239
            YST VDIWS+G IFAE+ T++ LF GDSEIDQLFRIFR LGTP+  VWP V S+ DYK 
Sbjct: 179 YYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 238

Query: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQI 294
           +FPKW     +  V  LDE+G  LLS+ML YDP KRIS K AL HP+F D+   +
Sbjct: 239 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 293


>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
          Length = 523

 Score =  331 bits (849), Expect = 4e-91
 Identities = 160/295 (54%), Positives = 214/295 (72%), Gaps = 4/295 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           ME Y K+EK+GEGTY  VYKGR K T  +VA+K+IRLE  EEG P TAIRE+SLLK+L+H
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 247

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
            NIV+L D++  D  L L+FE+L  DLK+Y+D    G  M    VK +LYQIL+G+ +CH
Sbjct: 248 ANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDC--GNIMSMHNVKLFLYQILRGLAYCH 305

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
            R+VLHRDLKPQNLLI++KG +KLADFGLARA  +P + Y++E +TLWYR P+VLLGS+ 
Sbjct: 306 RRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSE 365

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN- 239
           YST +D+W +G IF E+A+ +PLF G +  D+L  IFR LGTP+ E WP + S +++KN 
Sbjct: 366 YSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNY 425

Query: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQI 294
            FPK+KP  L +H   LD  G++L++K L Y+  KR+S + A+ H YF  L  +I
Sbjct: 426 NFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRI 480


>gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens]
          Length = 264

 Score =  326 bits (836), Expect = 1e-89
 Identities = 171/295 (57%), Positives = 206/295 (69%), Gaps = 37/295 (12%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           ME++ K+EKIGEGTYGVVYK R+K TG+VVA+KKIRL++E EGVPSTAIREISLLKEL H
Sbjct: 1   MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLD-SIPPGQYMDSSLVKSYLYQILQGIVFC 119
           PNIV L DV+  +++LYL+FEFL  DLKK++D S   G  +   L+KSYL+Q+LQG+ FC
Sbjct: 61  PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTG--IPLPLIKSYLFQLLQGLAFC 118

Query: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSA 179
           HS RVLHRDLKPQNLLI+ +G IKLADFGLARAFG+P+R YTHE                
Sbjct: 119 HSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHE---------------- 162

Query: 180 RYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239
                              T++ LF GDSEIDQLFRIFR LGTP+  VWP V S+ DYK 
Sbjct: 163 ------------------VTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKP 204

Query: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQI 294
           +FPKW     +  V  LDE+G  LLS+ML YDP KRIS K AL HP+F D+   +
Sbjct: 205 SFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPV 259


>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
          Length = 292

 Score =  324 bits (831), Expect = 5e-89
 Identities = 164/291 (56%), Positives = 211/291 (72%), Gaps = 5/291 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           M+ Y K+EKIGEGTYG V+K +++ T ++VA+K++RL+ ++EGVPS+A+REI LLKEL+H
Sbjct: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
            NIV L DVL  D +L L+FEF   DLKKY DS      +D  +VKS+L+Q+L+G+ FCH
Sbjct: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGD--LDPEIVKSFLFQLLKGLGFCH 118

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
           SR VLHRDLKPQNLLI+  G +KLADFGLARAFGIP+R Y+ E +TLWYR P+VL G+  
Sbjct: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178

Query: 181 YSTPVDIWSIGTIFAELATK-KPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239
           YST +D+WS G IFAELA   +PLF G+   DQL RIFR LGTP  E WP +  L DYK 
Sbjct: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237

Query: 240 TFPKW-KPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
            +P +    SL + V  L+  G DLL  +L  +P +RIS + AL HPYF+D
Sbjct: 238 PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288


>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
          Length = 502

 Score =  316 bits (810), Expect = 1e-86
 Identities = 152/298 (51%), Positives = 215/298 (72%), Gaps = 4/298 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E Y K++K+GEGTY  VYKG+ K T  +VA+K+IRLE  EEG P TAIRE+SLLK+L+H
Sbjct: 168 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 226

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
            NIV+L D++  +  L L+FE+L  DLK+YLD    G  ++   VK +L+Q+L+G+ +CH
Sbjct: 227 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDC--GNIINMHNVKLFLFQLLRGLAYCH 284

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
            ++VLHRDLKPQNLLI+++G +KLADFGLARA  IP + Y++E +TLWYR P++LLGS  
Sbjct: 285 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 344

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN- 239
           YST +D+W +G IF E+AT +PLF G +  +QL  IFR LGTP  E WP + S +++K  
Sbjct: 345 YSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTY 404

Query: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
            +PK++  +L SH   LD +G DLL+K+L ++   RIS + A+ HP+F  L  +I K+
Sbjct: 405 NYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKL 462


>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
          Length = 496

 Score =  316 bits (810), Expect = 1e-86
 Identities = 152/298 (51%), Positives = 215/298 (72%), Gaps = 4/298 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E Y K++K+GEGTY  VYKG+ K T  +VA+K+IRLE  EEG P TAIRE+SLLK+L+H
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLE-HEEGAPCTAIREVSLLKDLKH 220

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
            NIV+L D++  +  L L+FE+L  DLK+YLD    G  ++   VK +L+Q+L+G+ +CH
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDC--GNIINMHNVKLFLFQLLRGLAYCH 278

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
            ++VLHRDLKPQNLLI+++G +KLADFGLARA  IP + Y++E +TLWYR P++LLGS  
Sbjct: 279 RQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTD 338

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN- 239
           YST +D+W +G IF E+AT +PLF G +  +QL  IFR LGTP  E WP + S +++K  
Sbjct: 339 YSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTY 398

Query: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
            +PK++  +L SH   LD +G DLL+K+L ++   RIS + A+ HP+F  L  +I K+
Sbjct: 399 NYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKL 456


>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
          Length = 504

 Score =  314 bits (804), Expect = 7e-86
 Identities = 149/298 (50%), Positives = 211/298 (70%), Gaps = 4/298 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E Y K++K+GEGTY  V+KGR K T  +VA+K+IRLE  EEG P TAIRE+SLLK L+H
Sbjct: 171 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKNLKH 229

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
            NIV+L D++  D  L L+FE+L  DLK+YLD    G  M    VK +++Q+L+G+ +CH
Sbjct: 230 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHC--GNLMSMHNVKIFMFQLLRGLAYCH 287

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
            R++LHRDLKPQNLLI+++G +KLADFGLARA  +P + Y++E +TLWYR P+VLLGS  
Sbjct: 288 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 347

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN- 239
           YSTP+D+W +G I  E+AT +PLF G +  ++L  IFR LGTP  E WP V +  +++  
Sbjct: 348 YSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTY 407

Query: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
           +FP + P  L +H   LD +G+ LLS +L+Y+   R+S + AL+H YF  L  ++ ++
Sbjct: 408 SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQL 465


>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score =  314 bits (804), Expect = 7e-86
 Identities = 149/298 (50%), Positives = 211/298 (70%), Gaps = 4/298 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E Y K++K+GEGTY  V+KGR K T  +VA+K+IRLE  EEG P TAIRE+SLLK L+H
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKNLKH 199

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
            NIV+L D++  D  L L+FE+L  DLK+YLD    G  M    VK +++Q+L+G+ +CH
Sbjct: 200 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHC--GNLMSMHNVKIFMFQLLRGLAYCH 257

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
            R++LHRDLKPQNLLI+++G +KLADFGLARA  +P + Y++E +TLWYR P+VLLGS  
Sbjct: 258 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 317

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN- 239
           YSTP+D+W +G I  E+AT +PLF G +  ++L  IFR LGTP  E WP V +  +++  
Sbjct: 318 YSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTY 377

Query: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
           +FP + P  L +H   LD +G+ LLS +L+Y+   R+S + AL+H YF  L  ++ ++
Sbjct: 378 SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQL 435


>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score =  314 bits (804), Expect = 7e-86
 Identities = 149/298 (50%), Positives = 211/298 (70%), Gaps = 4/298 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E Y K++K+GEGTY  V+KGR K T  +VA+K+IRLE  EEG P TAIRE+SLLK L+H
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLE-HEEGAPCTAIREVSLLKNLKH 199

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
            NIV+L D++  D  L L+FE+L  DLK+YLD    G  M    VK +++Q+L+G+ +CH
Sbjct: 200 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHC--GNLMSMHNVKIFMFQLLRGLAYCH 257

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
            R++LHRDLKPQNLLI+++G +KLADFGLARA  +P + Y++E +TLWYR P+VLLGS  
Sbjct: 258 HRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTE 317

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN- 239
           YSTP+D+W +G I  E+AT +PLF G +  ++L  IFR LGTP  E WP V +  +++  
Sbjct: 318 YSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTY 377

Query: 240 TFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
           +FP + P  L +H   LD +G+ LLS +L+Y+   R+S + AL+H YF  L  ++ ++
Sbjct: 378 SFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQL 435


>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
          Length = 451

 Score =  273 bits (699), Expect = 1e-73
 Identities = 146/300 (48%), Positives = 192/300 (64%), Gaps = 21/300 (7%)

Query: 2   EDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHP 61
           + Y K+EK+GEG+Y  VYKG+ K  G++VA+K IRL+ EEEG P TAIRE SLLK L+H 
Sbjct: 115 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHA 173

Query: 62  NIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHS 121
           NIV L D++     L L+FE++  DL +Y+D  P G + D+  VK +L+Q+L+G+ + H 
Sbjct: 174 NIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDN--VKLFLFQLLRGLSYIHQ 231

Query: 122 RRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARY 181
           R +LHRDLKPQNLLI D G +KLADFGLARA  +P   Y++E +TLWYR P+VLLGS  Y
Sbjct: 232 RYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEY 291

Query: 182 STPVDIWSIGTIFAELATKKPLFHGDSEI-DQLFRIFRALGTPNNEVWPEVESLQDY--- 237
           ST +D+W +G IF E+      F G  +I DQL RIF  LGTPN + WP V SL  +   
Sbjct: 292 STCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPE 351

Query: 238 -------KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDL 290
                  KN    W   S  +H +       DL SK+L   P  R+S + AL+H YF+DL
Sbjct: 352 RFTLYSSKNLRQAWNKLSYVNHAE-------DLASKLLQCSPKNRLSAQAALSHEYFSDL 404


>gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]
          Length = 326

 Score =  257 bits (656), Expect = 1e-68
 Identities = 137/300 (45%), Positives = 197/300 (65%), Gaps = 16/300 (5%)

Query: 2   EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59
           + Y  + +IGEG YG V+K R  K  G+ VA+K++R+++ EEG+P + IRE+++L+ L  
Sbjct: 11  QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70

Query: 60  --HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMDSSLVKSYLYQ 111
             HPN+V L DV       ++++L L+FE +  DL  YLD +P PG  + +  +K  ++Q
Sbjct: 71  FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VPTETIKDMMFQ 128

Query: 112 ILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRS 171
           +L+G+ F HS RV+HRDLKPQN+L+   G IKLADFGLAR +   + + T   +TLWYR+
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-TSVVVTLWYRA 187

Query: 172 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 231
           PEVLL S+ Y+TPVD+WS+G IFAE+  +KPLF G S++DQL +I   +G P  E WP  
Sbjct: 188 PEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRD 246

Query: 232 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
            +L   +  F       +   V ++DE G DLL K L ++PAKRIS   AL+HPYF DL+
Sbjct: 247 VALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 304


>gi|4502741 cyclin-dependent kinase 6 [Homo sapiens]
          Length = 326

 Score =  257 bits (656), Expect = 1e-68
 Identities = 137/300 (45%), Positives = 197/300 (65%), Gaps = 16/300 (5%)

Query: 2   EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59
           + Y  + +IGEG YG V+K R  K  G+ VA+K++R+++ EEG+P + IRE+++L+ L  
Sbjct: 11  QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70

Query: 60  --HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMDSSLVKSYLYQ 111
             HPN+V L DV       ++++L L+FE +  DL  YLD +P PG  + +  +K  ++Q
Sbjct: 71  FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VPTETIKDMMFQ 128

Query: 112 ILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRS 171
           +L+G+ F HS RV+HRDLKPQN+L+   G IKLADFGLAR +   + + T   +TLWYR+
Sbjct: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-TSVVVTLWYRA 187

Query: 172 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 231
           PEVLL S+ Y+TPVD+WS+G IFAE+  +KPLF G S++DQL +I   +G P  E WP  
Sbjct: 188 PEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRD 246

Query: 232 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
            +L   +  F       +   V ++DE G DLL K L ++PAKRIS   AL+HPYF DL+
Sbjct: 247 VALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 304


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score =  252 bits (644), Expect = 2e-67
 Identities = 122/297 (41%), Positives = 196/297 (65%), Gaps = 14/297 (4%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E++  + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 411 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 470

Query: 61  PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
           PNIV+++++++  +  ++Y++  ++  DLK  ++++     PG+      VK+ + Q+L+
Sbjct: 471 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 524

Query: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
           G+   H   +LHRDLK  NLL+   G +K+ DFGLAR +G P++ YT   +TLWYR+PE+
Sbjct: 525 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPEL 584

Query: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
           LLG+  YST VD+WS+G IF EL T+KPLF G SEIDQ+ ++F+ LGTP+ ++WP    L
Sbjct: 585 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 644

Query: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
              K  TF +    +L       L + G DL++K L Y P +RIS +  L H YF +
Sbjct: 645 PAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 701


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score =  252 bits (644), Expect = 2e-67
 Identities = 122/297 (41%), Positives = 196/297 (65%), Gaps = 14/297 (4%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E++  + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479

Query: 61  PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
           PNIV+++++++  +  ++Y++  ++  DLK  ++++     PG+      VK+ + Q+L+
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 533

Query: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
           G+   H   +LHRDLK  NLL+   G +K+ DFGLAR +G P++ YT   +TLWYR+PE+
Sbjct: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPEL 593

Query: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
           LLG+  YST VD+WS+G IF EL T+KPLF G SEIDQ+ ++F+ LGTP+ ++WP    L
Sbjct: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 653

Query: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
              K  TF +    +L       L + G DL++K L Y P +RIS +  L H YF +
Sbjct: 654 PAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score =  252 bits (644), Expect = 2e-67
 Identities = 122/297 (41%), Positives = 196/297 (65%), Gaps = 14/297 (4%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E++  + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 447

Query: 61  PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
           PNIV+++++++  +  ++Y++  ++  DLK  ++++     PG+      VK+ + Q+L+
Sbjct: 448 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 501

Query: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
           G+   H   +LHRDLK  NLL+   G +K+ DFGLAR +G P++ YT   +TLWYR+PE+
Sbjct: 502 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPEL 561

Query: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
           LLG+  YST VD+WS+G IF EL T+KPLF G SEIDQ+ ++F+ LGTP+ ++WP    L
Sbjct: 562 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 621

Query: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
              K  TF +    +L       L + G DL++K L Y P +RIS +  L H YF +
Sbjct: 622 PAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 678


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score =  252 bits (644), Expect = 2e-67
 Identities = 122/297 (41%), Positives = 196/297 (65%), Gaps = 14/297 (4%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E++  + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 377 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 436

Query: 61  PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
           PNIV+++++++  +  ++Y++  ++  DLK  ++++     PG+      VK+ + Q+L+
Sbjct: 437 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 490

Query: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
           G+   H   +LHRDLK  NLL+   G +K+ DFGLAR +G P++ YT   +TLWYR+PE+
Sbjct: 491 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPEL 550

Query: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
           LLG+  YST VD+WS+G IF EL T+KPLF G SEIDQ+ ++F+ LGTP+ ++WP    L
Sbjct: 551 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 610

Query: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
              K  TF +    +L       L + G DL++K L Y P +RIS +  L H YF +
Sbjct: 611 PAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 667


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score =  252 bits (644), Expect = 2e-67
 Identities = 122/297 (41%), Positives = 196/297 (65%), Gaps = 14/297 (4%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E++  + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 166 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 225

Query: 61  PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
           PNIV+++++++  +  ++Y++  ++  DLK  ++++     PG+      VK+ + Q+L+
Sbjct: 226 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 279

Query: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
           G+   H   +LHRDLK  NLL+   G +K+ DFGLAR +G P++ YT   +TLWYR+PE+
Sbjct: 280 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPEL 339

Query: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
           LLG+  YST VD+WS+G IF EL T+KPLF G SEIDQ+ ++F+ LGTP+ ++WP    L
Sbjct: 340 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 399

Query: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
              K  TF +    +L       L + G DL++K L Y P +RIS +  L H YF +
Sbjct: 400 PAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 456


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score =  252 bits (644), Expect = 2e-67
 Identities = 122/297 (41%), Positives = 196/297 (65%), Gaps = 14/297 (4%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E++  + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 481

Query: 61  PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
           PNIV+++++++  +  ++Y++  ++  DLK  ++++     PG+      VK+ + Q+L+
Sbjct: 482 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 535

Query: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
           G+   H   +LHRDLK  NLL+   G +K+ DFGLAR +G P++ YT   +TLWYR+PE+
Sbjct: 536 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPEL 595

Query: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
           LLG+  YST VD+WS+G IF EL T+KPLF G SEIDQ+ ++F+ LGTP+ ++WP    L
Sbjct: 596 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSEL 655

Query: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
              K  TF +    +L       L + G DL++K L Y P +RIS +  L H YF +
Sbjct: 656 PAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 712


>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
          Length = 346

 Score =  251 bits (641), Expect = 5e-67
 Identities = 128/290 (44%), Positives = 182/290 (62%), Gaps = 8/290 (2%)

Query: 4   YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEE---GVPSTAIREISLLKELRH 60
           Y K++ +GEG +  VYK R K T Q+VA+KKI+L    E   G+  TA+REI LL+EL H
Sbjct: 12  YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71

Query: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
           PNI+ L D     S + L+F+F+  DL+  +        +  S +K+Y+   LQG+ + H
Sbjct: 72  PNIIGLLDAFGHKSNISLVFDFMETDLEVIIKD--NSLVLTPSHIKAYMLMTLQGLEYLH 129

Query: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
              +LHRDLKP NLL+D+ G +KLADFGLA++FG P R YTH+ +T WYR+PE+L G+  
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189

Query: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
           Y   VD+W++G I AEL  + P   GDS++DQL RIF  LGTP  E WP++ SL DY  T
Sbjct: 190 YGVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV-T 248

Query: 241 FPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
           F  + PG    H+     ++ LDL+  + +++P  RI+   AL   YF++
Sbjct: 249 FKSF-PGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score =  251 bits (640), Expect = 7e-67
 Identities = 121/297 (40%), Positives = 196/297 (65%), Gaps = 14/297 (4%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E++  + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469

Query: 61  PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
           PNIV+++++++  +  ++Y++  ++  DLK  ++++     PG+      VK+ + Q+L+
Sbjct: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 523

Query: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
           G+   H   +LHRDLK  NLL+   G +K+ DFGLAR +G P++ YT   +T WYR+PE+
Sbjct: 524 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 583

Query: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
           LLG+  YST VD+WS+G IF EL T+KPLF G+SEIDQ+ ++F+ LGTP+ ++WP    L
Sbjct: 584 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 643

Query: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
              K  TF +    +L       L + G DL++K L Y P +RIS +  L H YF +
Sbjct: 644 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score =  251 bits (640), Expect = 7e-67
 Identities = 121/297 (40%), Positives = 196/297 (65%), Gaps = 14/297 (4%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           +E++  + +I EGTYGVVY+ + K T ++VA+K++++E E+EG P T++REI+ + + +H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479

Query: 61  PNIVSLQDVLMQDS--RLYLIFEFLSMDLKKYLDSIP----PGQYMDSSLVKSYLYQILQ 114
           PNIV+++++++  +  ++Y++  ++  DLK  ++++     PG+      VK+ + Q+L+
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE------VKTLMIQLLR 533

Query: 115 GIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEV 174
           G+   H   +LHRDLK  NLL+   G +K+ DFGLAR +G P++ YT   +T WYR+PE+
Sbjct: 534 GVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPEL 593

Query: 175 LLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESL 234
           LLG+  YST VD+WS+G IF EL T+KPLF G+SEIDQ+ ++F+ LGTP+ ++WP    L
Sbjct: 594 LLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSEL 653

Query: 235 QDYKN-TFPKWKPGSLASHV-KNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
              K  TF +    +L       L + G DL++K L Y P +RIS +  L H YF +
Sbjct: 654 PVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710


>gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens]
          Length = 384

 Score =  244 bits (624), Expect = 5e-65
 Identities = 135/298 (45%), Positives = 185/298 (62%), Gaps = 7/298 (2%)

Query: 4   YTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNI 63
           Y  +EK+GEG+Y  VYKG  +  GQ+VA+K I + +EE GVP TAIRE SLLK L+H NI
Sbjct: 52  YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAEE-GVPFTAIREASLLKGLKHANI 110

Query: 64  VSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRR 123
           V L D++     L  +FE++  DL +Y+   P G +  +  V+ +++Q+L+G+ + H + 
Sbjct: 111 VLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHN--VRLFMFQLLRGLAYIHHQH 168

Query: 124 VLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSARYST 183
           VLHRDLKPQNLLI   G +KLADFGLARA  IP + Y+ E +TLWYR P+ LLG+  YS+
Sbjct: 169 VLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSS 228

Query: 184 PVDIWSIGTIFAELATKKPLFHGDSEI-DQLFRIFRALGTPNNEVWPEVESLQDYK-NTF 241
            +DIW  G IF E+   +PLF G S I +QL +I+  LG P  + WP V  L +Y    F
Sbjct: 229 ELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWF 288

Query: 242 PKWKPGSLASHVKNLDE--NGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM 297
           P   P SL      L       DL S+ML   P  R+S + AL H YF+ L +Q+ ++
Sbjct: 289 PLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQL 346


>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
          Length = 346

 Score =  240 bits (613), Expect = 1e-63
 Identities = 124/290 (42%), Positives = 180/290 (62%), Gaps = 5/290 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59
           M+ Y  + +IGEG +G+V+K +H  TG++VA+KK+ L   E+G P+ A+REI  L+E+  
Sbjct: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60

Query: 60  HPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
           +  +V L+ V        L FEF+  DL + +      + +  + VKSYL  +L+G+ FC
Sbjct: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQ--RPLAQAQVKSYLQMLLKGVAFC 118

Query: 120 HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-IRVYTHEAITLWYRSPEVLLGS 178
           H+  ++HRDLKP NLLI   G +K+ADFGLAR F     R+YTH+  T WYR+PE+L G+
Sbjct: 119 HANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGA 178

Query: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDY- 237
            +Y   VD+WS+G I  EL    PLF G ++I+QL  + R LGTPN +VWPE+  L DY 
Sbjct: 179 RQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYN 238

Query: 238 KNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYF 287
           K +F +  P  L   + ++    LDLL + L+Y P +RI+   AL H YF
Sbjct: 239 KISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288


>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
          Length = 360

 Score =  238 bits (607), Expect = 5e-63
 Identities = 117/292 (40%), Positives = 186/292 (63%), Gaps = 5/292 (1%)

Query: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
           ++++ K+ +IGEGTYG+VY+ R   T ++VA+KK+R++ E++G+P +++REI+LL  LRH
Sbjct: 36  VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95

Query: 61  PNIVSLQDVLMQD--SRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVF 118
           PNIV L++V++ +    ++L+  +   DL   L+++P       + VK  + Q+L+G+ +
Sbjct: 96  PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTP--FSEAQVKCIVLQVLRGLQY 153

Query: 119 CHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGS 178
            H   ++HRDLK  NLL+ DKG +K ADFGLARA+G+P++  T + +TLWYR+PE+LLG+
Sbjct: 154 LHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGT 213

Query: 179 ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK 238
              +T +D+W++G I AEL   +PL  G SEI Q+  I + LGTP+  +WP    L    
Sbjct: 214 TTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVG 273

Query: 239 NTFPKWKP-GSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289
               + +P  +L      L E GL LL  + +YDP KR +    L   YF +
Sbjct: 274 QYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE 325


>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
          Length = 1512

 Score =  231 bits (588), Expect = 8e-61
 Identities = 121/294 (41%), Positives = 182/294 (61%), Gaps = 14/294 (4%)

Query: 10   IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69
            IGEGTYG VYK R K TG++VA+KK+RL++E+EG P TAIREI +L++L H +I++++++
Sbjct: 711  IGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEI 770

Query: 70   LMQDS----------RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
            +                YL+FE++  DL   L+S     + + + +KS++ Q+++G+ +C
Sbjct: 771  VTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLES--GLVHFNENHIKSFMRQLMEGLDYC 828

Query: 120  HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-IRVYTHEAITLWYRSPEVLLGS 178
            H +  LHRD+K  N+L++++G IKLADFGLAR +     R YT++ ITLWYR PE+LLG 
Sbjct: 829  HKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGE 888

Query: 179  ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK 238
             RY+  +D+WS G I  EL TKKP+F  + E+ QL  I R  G+P   VWP+V  L  + 
Sbjct: 889  ERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFN 948

Query: 239  NTFPKWK-PGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
               PK +    L      +    LDL   ML  DP+KR + + AL   +  D++
Sbjct: 949  TMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVE 1002


>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
          Length = 1452

 Score =  231 bits (588), Expect = 8e-61
 Identities = 121/294 (41%), Positives = 182/294 (61%), Gaps = 14/294 (4%)

Query: 10   IGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDV 69
            IGEGTYG VYK R K TG++VA+KK+RL++E+EG P TAIREI +L++L H +I++++++
Sbjct: 711  IGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTHQSIINMKEI 770

Query: 70   LMQDS----------RLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFC 119
            +                YL+FE++  DL   L+S     + + + +KS++ Q+++G+ +C
Sbjct: 771  VTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLES--GLVHFNENHIKSFMRQLMEGLDYC 828

Query: 120  HSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIP-IRVYTHEAITLWYRSPEVLLGS 178
            H +  LHRD+K  N+L++++G IKLADFGLAR +     R YT++ ITLWYR PE+LLG 
Sbjct: 829  HKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYRPPELLLGE 888

Query: 179  ARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYK 238
             RY+  +D+WS G I  EL TKKP+F  + E+ QL  I R  G+P   VWP+V  L  + 
Sbjct: 889  ERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPDVIKLPYFN 948

Query: 239  NTFPKWK-PGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
               PK +    L      +    LDL   ML  DP+KR + + AL   +  D++
Sbjct: 949  TMKPKKQYRRKLREEFVFIPAAALDLFDYMLALDPSKRCTAEQALQCEFLRDVE 1002


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,006,850
Number of Sequences: 37866
Number of extensions: 466804
Number of successful extensions: 3547
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 757
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 984
Number of HSP's gapped (non-prelim): 956
length of query: 297
length of database: 18,247,518
effective HSP length: 102
effective length of query: 195
effective length of database: 14,385,186
effective search space: 2805111270
effective search space used: 2805111270
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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