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Search of human proteins with 195927037
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a
[Homo sapiens]
(1632 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho... 3341 0.0
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo... 3298 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 76 2e-13
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 72 3e-12
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 72 4e-12
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 72 6e-12
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 72 6e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 71 7e-12
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 71 1e-11
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 69 3e-11
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 69 4e-11
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 69 4e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 69 4e-11
gi|148746195 trichohyalin [Homo sapiens] 68 6e-11
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 67 2e-10
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 66 3e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 64 9e-10
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 64 9e-10
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 64 9e-10
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 64 9e-10
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 64 9e-10
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 64 1e-09
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 64 2e-09
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 63 3e-09
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 62 3e-09
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 62 3e-09
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 62 3e-09
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 62 3e-09
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 62 3e-09
gi|55956788 nucleolin [Homo sapiens] 62 5e-09
>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
sapiens]
Length = 1632
Score = 3341 bits (8663), Expect = 0.0
Identities = 1632/1632 (100%), Positives = 1632/1632 (100%)
Query: 1 MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ 60
MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ
Sbjct: 1 MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ 60
Query: 61 LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV 120
LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV
Sbjct: 61 LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV 120
Query: 121 GMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQ 180
GMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQ
Sbjct: 121 GMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQ 180
Query: 181 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 240
TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER
Sbjct: 181 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 240
Query: 241 AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 300
AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK
Sbjct: 241 AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 300
Query: 301 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM 360
KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM
Sbjct: 301 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM 360
Query: 361 NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ 420
NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ
Sbjct: 361 NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ 420
Query: 421 HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW 480
HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW
Sbjct: 421 HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW 480
Query: 481 WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY 540
WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY
Sbjct: 481 WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY 540
Query: 541 EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL 600
EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL
Sbjct: 541 EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL 600
Query: 601 IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK 660
IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK
Sbjct: 601 IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK 660
Query: 661 ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE 720
ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE
Sbjct: 661 ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE 720
Query: 721 VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS 780
VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS
Sbjct: 721 VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS 780
Query: 781 VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ 840
VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ
Sbjct: 781 VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ 840
Query: 841 LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP 900
LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP
Sbjct: 841 LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP 900
Query: 901 TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE 960
TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE
Sbjct: 901 TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE 960
Query: 961 AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK 1020
AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK
Sbjct: 961 AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK 1020
Query: 1021 SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY 1080
SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY
Sbjct: 1021 SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY 1080
Query: 1081 GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA 1140
GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA
Sbjct: 1081 GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA 1140
Query: 1141 CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS 1200
CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS
Sbjct: 1141 CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS 1200
Query: 1201 TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK 1260
TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK
Sbjct: 1201 TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK 1260
Query: 1261 NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY 1320
NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY
Sbjct: 1261 NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY 1320
Query: 1321 GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT 1380
GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT
Sbjct: 1321 GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT 1380
Query: 1381 ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR 1440
ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR
Sbjct: 1381 ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR 1440
Query: 1441 MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA 1500
MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA
Sbjct: 1441 MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA 1500
Query: 1501 CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ 1560
CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ
Sbjct: 1501 CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ 1560
Query: 1561 HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA 1620
HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA
Sbjct: 1561 HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA 1620
Query: 1621 SAKIKEEEAAKD 1632
SAKIKEEEAAKD
Sbjct: 1621 SAKIKEEEAAKD 1632
>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
sapiens]
Length = 1616
Score = 3298 bits (8552), Expect = 0.0
Identities = 1615/1632 (98%), Positives = 1615/1632 (98%), Gaps = 16/1632 (0%)
Query: 1 MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ 60
MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ
Sbjct: 1 MPARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ 60
Query: 61 LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV 120
LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV
Sbjct: 61 LCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV 120
Query: 121 GMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQ 180
GMADANSPPKPLSKPRTPRRSKSDGEAK EPSPSPRITRKSTRQ
Sbjct: 121 GMADANSPPKPLSKPRTPRRSKSDGEAK----------------PEPSPSPRITRKSTRQ 164
Query: 181 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 240
TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER
Sbjct: 165 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 224
Query: 241 AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 300
AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK
Sbjct: 225 AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 284
Query: 301 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM 360
KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM
Sbjct: 285 KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVM 344
Query: 361 NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ 420
NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ
Sbjct: 345 NSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQ 404
Query: 421 HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW 480
HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW
Sbjct: 405 HKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLGPINEW 464
Query: 481 WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY 540
WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY
Sbjct: 465 WITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYISKIVVEFLQSNSDSTY 524
Query: 541 EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL 600
EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL
Sbjct: 525 EDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDL 584
Query: 601 IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK 660
IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK
Sbjct: 585 IKLAGVTLGQRRAQARRQTIRHSTREKDRGPTKATTTKLVYQIFDTFFAEQIEKDDREDK 644
Query: 661 ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE 720
ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE
Sbjct: 645 ENAFKRRRCGVCEVCQQPECGKCKACKDMVKFGGSGRSKQACQERRCPNMAMKEADDDEE 704
Query: 721 VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS 780
VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS
Sbjct: 705 VDDNIPEMPSPKKMHQGKKKKQNKNRISWVGEAVKTDGKKSYYKKVCIDAETLEVGDCVS 764
Query: 781 VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ 840
VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ
Sbjct: 765 VIPDDSSKPLYLARVTALWEDSSNGQMFHAHWFCAGTDTVLGATSDPLELFLVDECEDMQ 824
Query: 841 LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP 900
LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP
Sbjct: 825 LSYIHSKVKVIYKAPSENWAMEGGMDPESLLEGDDGKTYFYQLWYDQDYARFESPPKTQP 884
Query: 901 TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE 960
TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE
Sbjct: 885 TEDNKFKFCVSCARLAEMRQKEIPRVLEQLEDLDSRVLYYSATKNGILYRVGDGVYLPPE 944
Query: 961 AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK 1020
AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK
Sbjct: 945 AFTFNIKLSSPVKRPRKEPVDEDLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIFCPKK 1004
Query: 1021 SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY 1080
SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY
Sbjct: 1005 SNGRPNETDIKIRVNKFYRPENTHKSTPASYHADINLLYWSDEEAVVDFKAVQGRCTVEY 1064
Query: 1081 GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA 1140
GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA
Sbjct: 1065 GEDLPECVQVYSMGGPNRFYFLEAYNAKSKSFEDPPNHARSPGNKGKGKGKGKGKPKSQA 1124
Query: 1141 CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS 1200
CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS
Sbjct: 1125 CEPSEPEIEIKLPKLRTLDVFSGCGGLSEGFHQAGISDTLWAIEMWDPAAQAFRLNNPGS 1184
Query: 1201 TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK 1260
TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK
Sbjct: 1185 TVFTEDCNILLKLVMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFK 1244
Query: 1261 NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY 1320
NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY
Sbjct: 1245 NSLVVSFLSYCDYYRPRFFLLENVRNFVSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQY 1304
Query: 1321 GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT 1380
GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT
Sbjct: 1305 GVAQTRRRAIILAAAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRT 1364
Query: 1381 ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR 1440
ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR
Sbjct: 1365 ITVRDTMSDLPEVRNGASALEISYNGEPQSWFQRQLRGAQYQPILRDHICKDMSALVAAR 1424
Query: 1441 MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA 1500
MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA
Sbjct: 1425 MRHIPLAPGSDWRDLPNIEVRLSDGTMARKLRYTHHDRKNGRSSSGALRGVCSCVEAGKA 1484
Query: 1501 CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ 1560
CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ
Sbjct: 1485 CDPAARQFNTLIPWCLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQ 1544
Query: 1561 HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA 1620
HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA
Sbjct: 1545 HRVVSVRECARSQGFPDTYRLFGNILDKHRQVGNAVPPPLAKAIGLEIKLCMLAKARESA 1604
Query: 1621 SAKIKEEEAAKD 1632
SAKIKEEEAAKD
Sbjct: 1605 SAKIKEEEAAKD 1616
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 76.3 bits (186), Expect = 2e-13
Identities = 85/347 (24%), Positives = 137/347 (39%), Gaps = 38/347 (10%)
Query: 27 RLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLL 86
++K E+ + EK KE + + + +T++ ++ + E K KEE +E
Sbjct: 437 KVKSEEKIKVVEKS-EKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKE---------- 485
Query: 87 NKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGE 146
E G E G E +E +A SP K +K +S E
Sbjct: 486 ------EEGGE--EEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEE 537
Query: 147 AKRSRD--PPASASQVTGIRAEPSPSPRITRKSTRQTTI---TSHFAKGPAK---RKPQE 198
AK + P A A+ P + K ++ + AK PAK + P E
Sbjct: 538 AKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAE 597
Query: 199 ESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE----KEEERD 254
K+ +KEE K E + V +E P + PE+AKS T+ E ++ +
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPV--KEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP 655
Query: 255 EKEEKRLRSQTKEPTPKQ-KLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKR 313
EKEE + + K P + K E+ +A ++ E K+E K P+ +
Sbjct: 656 EKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAK---SPEKAKSPV 712
Query: 314 RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE-KKMARAKTV 359
+ E K PEK + +E EK + K K P + K +AKT+
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL 759
Score = 73.6 bits (179), Expect = 2e-12
Identities = 70/258 (27%), Positives = 110/258 (42%), Gaps = 22/258 (8%)
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEP---- 167
+A+S A A SP K +K +P ++KS E + ++ P + S V P
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAK--SPEKAKSP-EKEEAKSPEKAKSPVKAEAKSPEKAK 681
Query: 168 SPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTS-- 225
SP + + + AK P K K + E AKS E K K++ + + S
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE-AKSPEKAKSPVKEEAKTPEKAKSPV 740
Query: 226 RERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAG 285
+E P A+ PE+AK+ E + KEE R + K +KEE +A
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK 800
Query: 286 VQADEDEDGDEKD---------EKKHRSQPKDLAAKRRPEEKEPEK--VNPQISDEKDED 334
ED EK+ K +P+++ K P++ E EK P+ ++EK +
Sbjct: 801 SPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPK-TEEKKDS 859
Query: 335 EKEEKRRKTTPKEPTEKK 352
+KEE +K PK E+K
Sbjct: 860 KKEEAPKKEAPKPKVEEK 877
Score = 72.4 bits (176), Expect = 3e-12
Identities = 77/314 (24%), Positives = 119/314 (37%), Gaps = 42/314 (13%)
Query: 65 ETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMAD 124
ET + +E+ E +V K+ E G E G E E + +
Sbjct: 453 ETVIVEEQTEETQVTEEVTEEEEKEAKEEEG----KEEEGGEEEEAEGGEEETKSPPAEE 508
Query: 125 ANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTIT 184
A SP K P +KS EAK E + SP + + +
Sbjct: 509 AASPEKEAKSP-VKEEAKSPAEAKSPEK-------------EEAKSPAEVKSPEKAKSPA 554
Query: 185 SHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSG 244
AK P + K E+ E AKS +K +K + ++E P A+ PE+AKS
Sbjct: 555 KEEAKSPPEAKSPEKEE-AKSPAEVKSPEKAKSP------AKEEAKSPAEAKSPEKAKSP 607
Query: 245 TRTEK----EEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 300
+ E E + KEE + ++ K P +K K EA++ +A E + K +
Sbjct: 608 VKEEAKSPAEAKSPVKEEAKSPAEVKSP---EKAKSPTKEEAKSPEKAKSPEKEEAKSPE 664
Query: 301 KHRS-------QPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK- 352
K +S P+ + + E K PEK + +E EK + K K P + K
Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724
Query: 353 --MARAKTVMNSKT 364
AKT +K+
Sbjct: 725 PVKEEAKTPEKAKS 738
Score = 68.2 bits (165), Expect = 6e-11
Identities = 93/433 (21%), Positives = 162/433 (37%), Gaps = 49/433 (11%)
Query: 6 APARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLE 65
+PA+ + P+ + +K+ + K VKE+ E E E
Sbjct: 586 SPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEE 645
Query: 66 TKLRKEELSEEGYLAKVKSLLNKDLSLE-NGAHAYNREVNGRLENGNQARSEARRVGMAD 124
K ++ S E AK + E V ++ +A+S + +
Sbjct: 646 AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSP 705
Query: 125 --ANSPPKPLSKPRTPRRSKSDGEAK---RSRDPPASASQVTGIRAEPSPSPRITRKSTR 179
A SP K +K +S EAK +++ P ++ P + + KS
Sbjct: 706 EKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPE 765
Query: 180 QTTITSHFAKGPAKRKPQEES----ERAKSDESIKEEDK-DQDEKRRRVTSRERVARPLP 234
T A+ PA + P++ E KS E K K D + + +E V P+
Sbjct: 766 AKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825
Query: 235 AEEP-------------ERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDRE 281
EE E K+ + EE++D K+E+ + + +P ++K + ++
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKP 885
Query: 282 ARAGVQADEDEDGDEKDEKKHRSQPKDLAAK------RRPEE------KEPEKV---NPQ 326
+ V+A ++E +D+KK + K+ AK +P+E KEP+ P
Sbjct: 886 KESKVEAKKEE---AEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPS 942
Query: 327 ISDEKDE------DEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDPD 380
EK E D KEEK +K K TE K ++ + PK + + D
Sbjct: 943 KPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA-EKAEKSSSTD 1001
Query: 381 LKYGQHPPDAVDE 393
K + P A ++
Sbjct: 1002 QKDSKPPEKATED 1014
Score = 65.1 bits (157), Expect = 5e-10
Identities = 82/352 (23%), Positives = 137/352 (38%), Gaps = 56/352 (15%)
Query: 33 RDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSL 92
+DSL + + +L H+ + + L+ +LR + L + + LLN ++L
Sbjct: 339 KDSLERQ---RSELEDRHQADIASYQEAIQQLDAELRNTKWEMAAQLREYQDLLNVKMAL 395
Query: 93 ENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRD 152
+ AY + + G E R+G P P S P
Sbjct: 396 DIEIAAYRKLLEG----------EECRIGFG-----PIPFSLPE---------------G 425
Query: 153 PPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGP--AKRKPQEESERAKSDESIK 210
P S T I+ + ++ KS ++T I + + +EE + AK +E +
Sbjct: 426 LPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKE 485
Query: 211 EEDKDQDEKRRRVTSRERVARPLPAEE---PER-AKSGTRTE----KEEERDEKEEKRLR 262
EE +++E E + PAEE PE+ AKS + E E + EKEE +
Sbjct: 486 EEGGEEEE----AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSP 541
Query: 263 SQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRS-----QPKDLAAKRRPEE 317
++ K P +K K EA++ +A E + K + +S P AK E
Sbjct: 542 AEVKSP---EKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEA 598
Query: 318 KEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE-KKMARAKTVMNSKTHPPK 368
K PEK + +E + + K K P E K +AK+ + P+
Sbjct: 599 KSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPE 650
Score = 62.8 bits (151), Expect = 3e-09
Identities = 73/288 (25%), Positives = 117/288 (40%), Gaps = 58/288 (20%)
Query: 125 ANSPPKPLSKPRTPRRSKSDGEAKRS--RDPPASASQVTGIRAEPSPSPRITRKSTRQTT 182
A SP K +K +P ++KS +AK + P A R+ P + ++
Sbjct: 736 AKSPVKEEAK--SPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEV 793
Query: 183 ITSHFAKGPAK---RKPQEESERAKSDES-IKEEDKDQDEKRR---RVTSRERVARPLPA 235
+ AK P K + P++E + + +S +KEE+K Q+ K + + E+
Sbjct: 794 KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKT 853
Query: 236 EEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEE----------PDREARAG 285
EE + +K +KE + + EEK+ + K K + K+E P++EA A
Sbjct: 854 EEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAK 913
Query: 286 VQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEK--EEKRR-- 341
V+ ED EK E + +P D AK + E ++ P+ D K+E K EEK +
Sbjct: 914 VEVKEDAKPKEKTEVA-KKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTE 972
Query: 342 -------KTTPKEP-------------------------TEKKMARAK 357
KT KEP TE K A+ K
Sbjct: 973 AKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
Score = 40.8 bits (94), Expect = 0.011
Identities = 55/280 (19%), Positives = 101/280 (36%), Gaps = 44/280 (15%)
Query: 2 PARTAPARVPTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQL 61
PA P + + + P+ + LK E EKE K+ E +++ +K +
Sbjct: 777 PADKFPEKAKSPVKEEVKSPEKAKSPLK--EDAKAPEKEIPKK------EEVKSPVKEEE 828
Query: 62 CDLETKLRK--EELSEEGYLAKVKSLLNKDLSLENGAHA------YNREVNGRLENGNQA 113
E K+++ ++ EE A K+ KD E + +E ++
Sbjct: 829 KPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKES 888
Query: 114 RSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRI 173
+ EA++ D P P + K D A+P +
Sbjct: 889 KVEAKKEEAEDKKKVPTPEKEAPAKVEVKED--------------------AKPKEKTEV 928
Query: 174 TRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPL 233
+K AK KP E+ E A + KEE + E++ + ++ +
Sbjct: 929 AKKEPDD-------AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKT 981
Query: 234 PAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQK 273
++EP + K+ + EK D+K+ K T++ K K
Sbjct: 982 LSKEPSKPKA-EKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 72.4 bits (176), Expect = 3e-12
Identities = 64/289 (22%), Positives = 119/289 (41%), Gaps = 27/289 (9%)
Query: 95 GAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPP 154
G +R+ +G+ E Q +E R D + + R + + + +R R+
Sbjct: 135 GERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQ 194
Query: 155 ASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDE----SIK 210
T R R + T T R+ + E ER K E S +
Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
Query: 211 EEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTP 270
E ++D++ +R R R+R R E K RTE++ E + K E R R + +E
Sbjct: 255 ETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRE-RQRERERERER 313
Query: 271 KQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQP--------------KDLAAKRRPE 316
+K + E +RE Q + + D +++ E+K + Q + A + R
Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERER 373
Query: 317 EKEPEKVNPQISDEKDED---EKEEKRRKTTPKE-----PTEKKMARAK 357
E+E ++ + + +E++ D +++++R + T K+ TEK+ R K
Sbjct: 374 ERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREK 422
Score = 70.1 bits (170), Expect = 2e-11
Identities = 54/252 (21%), Positives = 101/252 (40%), Gaps = 13/252 (5%)
Query: 106 RLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRA 165
R N + R R + + K + R K D +R RD + T
Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 166 EPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTS 225
+ R+ R+ +G R+ + ER + ++ KE ++ D +R+R T
Sbjct: 114 DRQREKERNRQKERERETEREGERG-RDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 226 RERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAG 285
R R +E ER K+ + +E ER ++E + + E +++ + E + E
Sbjct: 173 RNR------QKEREREKN-RQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 286 VQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTP 345
Q D + D K E++ Q + A R E++ E+ E+D D ++R+K
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKER-----ERERDRDRDRDRRQKERE 280
Query: 346 KEPTEKKMARAK 357
++ K+ R +
Sbjct: 281 RQTDRKRQRRTE 292
Score = 70.1 bits (170), Expect = 2e-11
Identities = 78/366 (21%), Positives = 151/366 (41%), Gaps = 34/366 (9%)
Query: 32 ERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLS 91
ER+ + E +E+ QTE Q K R+E E K +D
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENK--TEDRH 205
Query: 92 LENGAHAYN-REVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRS 150
E G RE E Q E R + + + + R ++ D E +R
Sbjct: 206 SERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERE 265
Query: 151 RDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIK 210
RD R + + RK R+T + +R+ + E ER ++ + +
Sbjct: 266 RDRDRDRD-----RRQKERERQTDRKRQRRTE-RDRETERKRERQRERERERERNRKRER 319
Query: 211 EEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERD-----------EKEEK 259
E +++++ +R+R T R+R E+ K +TE + ER+ E+E +
Sbjct: 320 ERERERERERQRETERDR-------EKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372
Query: 260 RLRSQTKEPTPKQKLKE---EPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKR--- 313
R R + ++ +++ +E + DR+ Q ++D DG +++ +K R + KD ++R
Sbjct: 373 RERERDRQSAREREERERDRDRDRQKERERQTEKDRDG-QRETEKQREREKDRESERGRE 431
Query: 314 RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCG 373
R E+E +K + + + + + +R+++T + AR+ V + P + I+
Sbjct: 432 RGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWK 491
Query: 374 QYLDDP 379
+DP
Sbjct: 492 SSPEDP 497
Score = 65.1 bits (157), Expect = 5e-10
Identities = 72/330 (21%), Positives = 126/330 (38%), Gaps = 16/330 (4%)
Query: 22 DDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTE---IKNQLCDLETKLRKEELSEEGY 78
D R R ++ ER+ E+E E+ QT+ + + D E K R+ + E
Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAE-KERERQTDRERQ 168
Query: 79 LAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQAR-SEARRVGMADANSPPKPLSKPRT 137
++ + +N RE EN + R SE R + + + K +T
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT 228
Query: 138 PRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQ 197
R + +R R+ A + + E R R + RK Q
Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
Query: 198 EESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKE 257
+ER + E +E ++++ +R R RER E ER + R + + E+E
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRER------ERERERERERQRETERDREKERE 342
Query: 258 EKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEE 317
KR R + ++ E R+A + + + D E++ R + +D R +
Sbjct: 343 RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRD-----RDRQ 397
Query: 318 KEPEKVNPQISDEKDEDEKEEKRRKTTPKE 347
KE E+ + D + E EK+ +R K E
Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRESE 427
Score = 56.2 bits (134), Expect = 2e-07
Identities = 57/228 (25%), Positives = 101/228 (44%), Gaps = 19/228 (8%)
Query: 139 RRSKSDGEAKRSRDPPASASQVTGIRAEPS-PSPRITRKSTRQTTITSHFAKGPAKRKPQ 197
RR E+ R R + G E + R R+ RQT + KR+ +
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTE-----RETDRKRERR 82
Query: 198 EESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKE 257
E +R + + +E +D++++R R T RER + E ER + R E+E ER+ +
Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQ----REKERNRQKER-ERETEREGE- 136
Query: 258 EKRLRSQTKEPTPKQKLKEEPDREARAGVQAD-EDEDGDEKDEKKHRSQPKDLAAKRRPE 316
R + ++ +++ + + D E Q D E + E++ +K R + K+ +RR
Sbjct: 137 ----RGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKN-RQERRER 191
Query: 317 EKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKT 364
E++ EK N + D E +E +R + T E K+ + KT
Sbjct: 192 ERQREKEN-KTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Score = 50.4 bits (119), Expect = 1e-05
Identities = 45/173 (26%), Positives = 74/173 (42%), Gaps = 14/173 (8%)
Query: 192 AKRKP--QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK 249
++R+P QE R ++ K+ D D D +R R RER E K R EK
Sbjct: 27 SRRRPGSQESPRRRGLGQAHKDADGD-DRERNRQKERERRREKRQTERETDRKRERRREK 85
Query: 250 E--------EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEK--DE 299
+ ER EK QT +Q+ KE ++ R E E G ++ D
Sbjct: 86 DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
Query: 300 KKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 352
++ R + +D A K R + + E+ + + E E+E+ R++ +E +K
Sbjct: 146 QRERERQRD-AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREK 197
Score = 39.3 bits (90), Expect = 0.032
Identities = 35/154 (22%), Positives = 68/154 (44%), Gaps = 14/154 (9%)
Query: 217 DEKRRRVTSRERVARPLPAEEPERAKSGTRT-----EKEEERD----EKEEKRLRSQTKE 267
D RRR S+E R + + A R E+E R+ E+E R R + +E
Sbjct: 25 DFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRRE 84
Query: 268 PTPKQK----LKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKV 323
+K + + DRE Q D + D +++++++R + ++ +R E +
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERD-RQREKERNRQKERERETEREGERGRDRQT 143
Query: 324 NPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357
+ Q E+ D ++E+ R+T + + + R K
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQK 177
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 72.0 bits (175), Expect = 4e-12
Identities = 67/291 (23%), Positives = 121/291 (41%), Gaps = 78/291 (26%)
Query: 138 PRRSKSDG-----------EAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSH 186
PR+ K DG E +RSR P S S R+S R++ SH
Sbjct: 237 PRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSP---------------RRSPRRSRSRSH 281
Query: 187 FAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTR 246
+G E ER K + ++ E K+++++RRR S +R + ER +S +R
Sbjct: 282 HREGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSR 341
Query: 247 T--------------EKEEERD---------------EKEEKRLRSQTKEPTPKQKLKEE 277
+ EKE ER EKE +R R ++KE + +++E+
Sbjct: 342 SRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEK 401
Query: 278 PDREARAGVQADEDEDGDEKD---------EKKHRSQPKDLAAKRRPEEKEPEKVNPQIS 328
+E + + +D+ +K+ E+KHRS+ + A +R + EK + +
Sbjct: 402 KHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKN 461
Query: 329 DEKDEDEK--------------EEKRRKTTPKEPTEKKMARAKTVMNSKTH 365
+ K++ K + K+R+ +P + +K +R+K + + H
Sbjct: 462 ESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDH 512
Score = 70.9 bits (172), Expect = 1e-11
Identities = 71/305 (23%), Positives = 133/305 (43%), Gaps = 59/305 (19%)
Query: 108 ENGNQARSEA-RRVGMADANSPPKPLSKPRTPRRSKS-------------DGEAKRSRDP 153
++G + E R V + SP + LS R+PRRS+S D E +R ++
Sbjct: 242 KDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKER 301
Query: 154 PASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQE------ESERAKSDE 207
+ E S I R R+ + + + ++ + ++ + ER K +E
Sbjct: 302 QRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENE 361
Query: 208 SIKEEDKDQDEKR----------RRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKE 257
+ D+D D++R R S+E+ +R E+ + R ++++RD K+
Sbjct: 362 RGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKK 421
Query: 258 EK-----------------------RLRSQTKEPTPKQK--LKEEPDREARAGVQADEDE 292
EK R RS++KE + K K KE+ ++ +R+G Q D
Sbjct: 422 EKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDS 481
Query: 293 DGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 352
EK +K+ S K+ + KR ++ K + SD KD+ +K ++RR + ++ +++K
Sbjct: 482 V--EKSKKREHSPSKEKSRKRSRSKERSHKRDH--SDSKDQSDKHDRRRSQSIEQESQEK 537
Query: 353 MARAK 357
+ K
Sbjct: 538 QHKNK 542
Score = 50.8 bits (120), Expect = 1e-05
Identities = 40/196 (20%), Positives = 84/196 (42%), Gaps = 15/196 (7%)
Query: 178 TRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEE 237
TR I +G + E R++S + R R RE E
Sbjct: 235 TRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRE 294
Query: 238 PERAKSGTRTEKEEERDEKEEKRLRS-----QTKEPTPKQKLKEEPDREARAGVQADEDE 292
ER K R E+E + EKE +R RS + + +++ + R G + D D
Sbjct: 295 LEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDR 354
Query: 293 DGDEKDEK---------KHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKT 343
+ ++++E+ K R ++ +R E + ++ ++ ++K +++K+++R +
Sbjct: 355 EREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRD 414
Query: 344 TPKE-PTEKKMARAKT 358
++ EKK +R+++
Sbjct: 415 DKRDSKKEKKHSRSRS 430
Score = 39.3 bits (90), Expect = 0.032
Identities = 50/263 (19%), Positives = 96/263 (36%), Gaps = 34/263 (12%)
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKS 143
S +++L E RE R + ++RS R + + S + S+ R+ R K
Sbjct: 289 SSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRS-RDRKG 347
Query: 144 DGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERA 203
D +R RD G R + + ++ + +K R EE +
Sbjct: 348 D---RRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHK 404
Query: 204 KSDESIKEEDKDQDEKRRRVTSRERV----------ARPLPAEEPERAKSGTRTEKEEER 253
+ + + D +D K+ + SR R +R R+K + K E +
Sbjct: 405 EDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESK 464
Query: 254 D-----------------EKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDE 296
+ EK +KR S +KE + K+ +E + +D + D+
Sbjct: 465 EKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRD---HSDSKDQSDK 521
Query: 297 KDEKKHRSQPKDLAAKRRPEEKE 319
D ++ +S ++ K+ + E
Sbjct: 522 HDRRRSQSIEQESQEKQHKNKDE 544
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 71.6 bits (174), Expect = 6e-12
Identities = 62/254 (24%), Positives = 114/254 (44%), Gaps = 25/254 (9%)
Query: 114 RSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRI 173
+S R+ G + +++ K S ++ R K RSR S S+ R SP +
Sbjct: 299 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 358
Query: 174 TR-KSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARP 232
++ + R++ SH ++ K ++ E+ K E +KE+D++++ +R + +E+
Sbjct: 359 SKSRERRKSRSRSH-----SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK---- 409
Query: 233 LPAEEPERAKSGTRT---EKEEERD-EKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQA 288
ER K+ R EK+ E+D EK+ +R R + E ++ ++E D+E
Sbjct: 410 ------ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 463
Query: 289 DEDEDGDEKDEKKHRSQPKDLAAKR--RPEEKEPEKVNPQISDEKDEDEKEEKR---RKT 343
++ D K +KK R+ P+ A R R +E + + S K KR R
Sbjct: 464 SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 523
Query: 344 TPKEPTEKKMARAK 357
+P+ +K R K
Sbjct: 524 SPRSRNKKDKKREK 537
Score = 68.6 bits (166), Expect = 5e-11
Identities = 69/316 (21%), Positives = 129/316 (40%), Gaps = 45/316 (14%)
Query: 96 AHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPA 155
+H+ + + + + RS +R+ + SP K SK R R+S+S SRD
Sbjct: 322 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS---RSHSRD--- 375
Query: 156 SASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKD 215
RK TR+ K ++ ++E ER K E KE K+
Sbjct: 376 ------------------KRKDTREKIKEKERVK---EKDREKEREREKEREKEKERGKN 414
Query: 216 QDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLK 275
+D + R RE+ E E+ R +++E+ +KE++R + ++KE K+K K
Sbjct: 415 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK-K 473
Query: 276 EEPDREARAGVQADEDEDGDEKDEKKHRSQ-----PKDLAAKRRPEEKEPEKVNPQISDE 330
++ R A ++ ++ RS+ P+ +R + P + D+
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533
Query: 331 KDEDEKE------EKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLKYG 384
K E E++ E+ R T+ ++ + + + K NS + K ++ +PD
Sbjct: 534 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEK-----EHNKEPDSSVS 588
Query: 385 QHPPDAVDEPQMLTNE 400
+ D D P+ N+
Sbjct: 589 KEVDDK-DAPRTEENK 603
Score = 63.5 bits (153), Expect = 2e-09
Identities = 45/193 (23%), Positives = 100/193 (51%), Gaps = 14/193 (7%)
Query: 174 TRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPL 233
+R TR + +S +K ++RK + R++S + KD RRR S +
Sbjct: 308 SRSHTRSKSRSS--SKSHSRRKRSQSKHRSRSHNRSRSRQKD----RRRSKSPHKKRSKS 361
Query: 234 PAEEPERAKSGTRTEKEEERDE-KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDE 292
R++S +R ++++ R++ KE++R++ + +E +++ + E ++E D++
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 421
Query: 293 DGD-EKDEKKHRSQPKDLAAKR---RPEEKEPEKVNPQISD---EKDEDEKEEKRRKTTP 345
+ D EKD++K R + ++ ++ + +EKE +K + D E DE K++K+ +T P
Sbjct: 422 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 481
Query: 346 KEPTEKKMARAKT 358
+ + +R+ +
Sbjct: 482 RSYNASRRSRSSS 494
Score = 56.6 bits (135), Expect = 2e-07
Identities = 57/259 (22%), Positives = 103/259 (39%), Gaps = 28/259 (10%)
Query: 120 VGMADANSPPKPLS--------KPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSP 171
V AD NS P+ L+ +P S + P A+A ++ + +
Sbjct: 227 VEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQ 286
Query: 172 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKS-DESIKEEDKDQDEKRRRVTSRERVA 230
+ + S+ KG R R+ S S ++ + + R SR R
Sbjct: 287 SFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK 346
Query: 231 RPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADE 290
++ P + +S +R E+ + R + R T+E +++ +E DRE E
Sbjct: 347 DRRRSKSPHKKRSKSR-ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK-------E 398
Query: 291 DEDGDEKDEKKHRSQPKDLAAKR-----------RPEEKEPEKVNPQISDEKDEDEKEEK 339
E E++++K R + KD +R R E+E E + +++ E +KE++
Sbjct: 399 REREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 458
Query: 340 RRKTTPKEPTEKKMARAKT 358
R K KE EK+ K+
Sbjct: 459 REKDRSKEIDEKRKKDKKS 477
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 71.6 bits (174), Expect = 6e-12
Identities = 62/254 (24%), Positives = 114/254 (44%), Gaps = 25/254 (9%)
Query: 114 RSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRI 173
+S R+ G + +++ K S ++ R K RSR S S+ R SP +
Sbjct: 183 KSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKR 242
Query: 174 TR-KSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARP 232
++ + R++ SH ++ K ++ E+ K E +KE+D++++ +R + +E+
Sbjct: 243 SKSRERRKSRSRSH-----SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEK---- 293
Query: 233 LPAEEPERAKSGTRT---EKEEERD-EKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQA 288
ER K+ R EK+ E+D EK+ +R R + E ++ ++E D+E
Sbjct: 294 ------ERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDR 347
Query: 289 DEDEDGDEKDEKKHRSQPKDLAAKR--RPEEKEPEKVNPQISDEKDEDEKEEKR---RKT 343
++ D K +KK R+ P+ A R R +E + + S K KR R
Sbjct: 348 SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSP 407
Query: 344 TPKEPTEKKMARAK 357
+P+ +K R K
Sbjct: 408 SPRSRNKKDKKREK 421
Score = 68.6 bits (166), Expect = 5e-11
Identities = 69/316 (21%), Positives = 129/316 (40%), Gaps = 45/316 (14%)
Query: 96 AHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPA 155
+H+ + + + + RS +R+ + SP K SK R R+S+S SRD
Sbjct: 206 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRS---RSHSRD--- 259
Query: 156 SASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKD 215
RK TR+ K ++ ++E ER K E KE K+
Sbjct: 260 ------------------KRKDTREKIKEKERVK---EKDREKEREREKEREKEKERGKN 298
Query: 216 QDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLK 275
+D + R RE+ E E+ R +++E+ +KE++R + ++KE K+K K
Sbjct: 299 KDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRK-K 357
Query: 276 EEPDREARAGVQADEDEDGDEKDEKKHRSQ-----PKDLAAKRRPEEKEPEKVNPQISDE 330
++ R A ++ ++ RS+ P+ +R + P + D+
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417
Query: 331 KDEDEKE------EKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLKYG 384
K E E++ E+ R T+ ++ + + + K NS + K ++ +PD
Sbjct: 418 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEK-----EHNKEPDSSVS 472
Query: 385 QHPPDAVDEPQMLTNE 400
+ D D P+ N+
Sbjct: 473 KEVDDK-DAPRTEENK 487
Score = 63.5 bits (153), Expect = 2e-09
Identities = 45/193 (23%), Positives = 100/193 (51%), Gaps = 14/193 (7%)
Query: 174 TRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPL 233
+R TR + +S +K ++RK + R++S + KD RRR S +
Sbjct: 192 SRSHTRSKSRSS--SKSHSRRKRSQSKHRSRSHNRSRSRQKD----RRRSKSPHKKRSKS 245
Query: 234 PAEEPERAKSGTRTEKEEERDE-KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDE 292
R++S +R ++++ R++ KE++R++ + +E +++ + E ++E D++
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKER 305
Query: 293 DGD-EKDEKKHRSQPKDLAAKR---RPEEKEPEKVNPQISD---EKDEDEKEEKRRKTTP 345
+ D EKD++K R + ++ ++ + +EKE +K + D E DE K++K+ +T P
Sbjct: 306 EKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPP 365
Query: 346 KEPTEKKMARAKT 358
+ + +R+ +
Sbjct: 366 RSYNASRRSRSSS 378
Score = 56.6 bits (135), Expect = 2e-07
Identities = 57/259 (22%), Positives = 103/259 (39%), Gaps = 28/259 (10%)
Query: 120 VGMADANSPPKPLS--------KPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSP 171
V AD NS P+ L+ +P S + P A+A ++ + +
Sbjct: 111 VEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQ 170
Query: 172 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKS-DESIKEEDKDQDEKRRRVTSRERVA 230
+ + S+ KG R R+ S S ++ + + R SR R
Sbjct: 171 SFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQK 230
Query: 231 RPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADE 290
++ P + +S +R E+ + R + R T+E +++ +E DRE E
Sbjct: 231 DRRRSKSPHKKRSKSR-ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK-------E 282
Query: 291 DEDGDEKDEKKHRSQPKDLAAKR-----------RPEEKEPEKVNPQISDEKDEDEKEEK 339
E E++++K R + KD +R R E+E E + +++ E +KE++
Sbjct: 283 REREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKE 342
Query: 340 RRKTTPKEPTEKKMARAKT 358
R K KE EK+ K+
Sbjct: 343 REKDRSKEIDEKRKKDKKS 361
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 71.2 bits (173), Expect = 7e-12
Identities = 47/186 (25%), Positives = 90/186 (48%), Gaps = 9/186 (4%)
Query: 180 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 239
Q SH +K + Q E + + ++E K + E R+ RER R E+
Sbjct: 18 QMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKER 77
Query: 240 RAKSGTRTEKEEERDEKEEKRLRSQTKEPTP-------KQKLKEEPDREARAGVQADEDE 292
+ + G + +K E + E+ E++ R + KE K+K K+E R ++ G + + E
Sbjct: 78 KRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137
Query: 293 DGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE-DEKEEKRRKTTPKEPTEK 351
+ +++E+K R + K+ K R ++ ++ Q+ ++++E EKE K RK + E+
Sbjct: 138 ER-KREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 352 KMARAK 357
K R +
Sbjct: 197 KKERER 202
Score = 70.5 bits (171), Expect = 1e-11
Identities = 44/173 (25%), Positives = 87/173 (50%), Gaps = 10/173 (5%)
Query: 195 KPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE----KE 250
K + ESER K ++ ++++++R+R ++ EE ER K E +E
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
Query: 251 EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLA 310
+E+ +K+EK+ R +T + +++ KEE RE R + ++E E++ K+ + + +
Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQV 171
Query: 311 AKRRPEEKEPEKVNPQISD------EKDEDEKEEKRRKTTPKEPTEKKMARAK 357
++ E KE E+ + + +K+ + KE + RK K+ E+K R K
Sbjct: 172 GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224
Score = 69.7 bits (169), Expect = 2e-11
Identities = 60/228 (26%), Positives = 100/228 (43%), Gaps = 30/228 (13%)
Query: 116 EARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITR 175
E R+ G + S K + R R+ + + E KR R + E R +
Sbjct: 46 ETRKEGKKERESERKKERREREKRKREREKERKRERGKKEK-------KGERKKEERERK 98
Query: 176 KSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPA 235
K R+ K KRK +E+ ER ++ + KE ++ ++ KR RER
Sbjct: 99 KRRREKENKEGEEK--EKRKKKEKKERGRTSKEGKERERKEERKREERKERER------- 149
Query: 236 EEPERAKSGTRTEKEEERDEKE-EKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDG 294
+ E+E+ER+ KE +KR R Q E ++K KE +R+ R + + E
Sbjct: 150 ---------KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKR---ERNRKERK 197
Query: 295 DEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK 342
E++ K+ R + K+ K+ +KE +K EK+ ++E K RK
Sbjct: 198 KERERKERRERKKE-RKKKEERKKERQKDRQTNWREKERGKRERKERK 244
Score = 66.2 bits (160), Expect = 2e-10
Identities = 38/160 (23%), Positives = 87/160 (54%), Gaps = 3/160 (1%)
Query: 189 KGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE 248
K +R+ + + ER K ++ + + ++++ K+RR + + + K RT
Sbjct: 68 KRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTS 127
Query: 249 KE-EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPK 307
KE +ER+ KEE++ R + KE ++K + E +RE + + + + G++++E+K + + +
Sbjct: 128 KEGKERERKEERK-REERKE-RERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE 185
Query: 308 DLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKE 347
+R +E++ E+ + + K E +K+E+R+K K+
Sbjct: 186 RKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
Score = 62.4 bits (150), Expect = 3e-09
Identities = 40/163 (24%), Positives = 88/163 (53%), Gaps = 11/163 (6%)
Query: 193 KRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE 252
K+ +++ ER + ++E+K+ +EK +R ++ E +K G E++EE
Sbjct: 86 KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK-------ERGRTSKEGKERERKEE 138
Query: 253 RDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAK 312
R ++EE++ R + KE ++K +E +R+ R Q E E+ ++ E+K R + ++ K
Sbjct: 139 R-KREERKERERKKE--EREKERERKERKKRERKQVGEKEEERKEKERKERKK-RERNRK 194
Query: 313 RRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMAR 355
R +E+E ++ + + K ++E++++R+K EK+ +
Sbjct: 195 ERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237
Score = 57.0 bits (136), Expect = 1e-07
Identities = 44/206 (21%), Positives = 90/206 (43%), Gaps = 4/206 (1%)
Query: 101 REVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDP-PASASQ 159
RE+ R E G + R R+ + + K R R K + + +R ++ +
Sbjct: 43 REIETRKE-GKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR 101
Query: 160 VTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEK 219
E + +K ++ TS +G + + +E + + K+E+++++ +
Sbjct: 102 REKENKEGEEKEKRKKKEKKERGRTSK--EGKERERKEERKREERKERERKKEEREKERE 159
Query: 220 RRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPD 279
R+ RER EE + + R ++E R E++++R R + +E ++K KEE
Sbjct: 160 RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERK 219
Query: 280 REARAGVQADEDEDGDEKDEKKHRSQ 305
+E + Q + E K E+K R +
Sbjct: 220 KERQKDRQTNWREKERGKRERKERKK 245
Score = 41.6 bits (96), Expect = 0.006
Identities = 47/228 (20%), Positives = 90/228 (39%), Gaps = 25/228 (10%)
Query: 54 QTEIKNQLCDLETKL--RKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGN 111
Q+EI+ + ++ET+ +KE SE + + ++ E +E G +
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSP 171
+ R + RR + K R ++ E K R
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE--------------RERKEERK 140
Query: 172 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKR---RRVTSRER 228
R RK + + +RK +E + + +E KE+++ + +KR R+ +ER
Sbjct: 141 REERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER 200
Query: 229 VARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKE 276
+ E ER K R +KEE + E+++ R + ++ K++ KE
Sbjct: 201 ERK----ERRERKKE--RKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 36.6 bits (83), Expect = 0.20
Identities = 30/120 (25%), Positives = 51/120 (42%), Gaps = 18/120 (15%)
Query: 249 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKD 308
+ E R+ + E R + K+ ++ KE +RE R + EK+ K+ R + K+
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKRER--------EKERKRERGK-KE 85
Query: 309 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPK 368
+R+ EE+E +K EKE K + K ++K R +T K K
Sbjct: 86 KKGERKKEERERKK---------RRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERK 136
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 70.9 bits (172), Expect = 1e-11
Identities = 47/197 (23%), Positives = 94/197 (47%), Gaps = 20/197 (10%)
Query: 188 AKGPAKRKPQEESERAKSDESIKEEDKDQ-DEKRRRVTSRERVARPLPAEEPERAKSGTR 246
A GP +K ++++ + S++S +EE++ Q ++ +RV P P + +A +
Sbjct: 70 ANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLP-PGKAAAKASESSS 128
Query: 247 TEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQP 306
+E+ + D++E+++ + K P+ K + P ++A++ +D D D +DE +P
Sbjct: 129 SEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKS---SDSDSDSSSEDEPPKNQKP 185
Query: 307 KDLAAKRRPEEKEPEK---VNPQISDEK------------DEDEKEEKRRKTTPKEPTEK 351
K + + K P K P+I++ K D+ EE++ TPK+ K
Sbjct: 186 KITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK 245
Query: 352 KMARAKTVMNSKTHPPK 368
K AK + + T P +
Sbjct: 246 KQVVAKAPVKAATTPTR 262
Score = 63.5 bits (153), Expect = 2e-09
Identities = 62/293 (21%), Positives = 115/293 (39%), Gaps = 43/293 (14%)
Query: 109 NGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPP--ASASQVTGIRAE 166
NG A+ ++ +D+ + + + P K+ AKR PP A+A +E
Sbjct: 71 NGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSE 130
Query: 167 PSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVT-- 224
S +Q + A + P ++++ + SD ED+ ++ ++T
Sbjct: 131 ESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPV 190
Query: 225 --SRERVARPLPAEEPER------AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQ---- 272
+ A P PA + A S + + D+ EE++ + K+ PK+
Sbjct: 191 TVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVA 250
Query: 273 ----KLKEEPDREARAGVQADEDEDGDEKDEKKHRSQP-------------KDLAA---K 312
K P R++ + + DE+ ++K K++ P K L K
Sbjct: 251 KAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPK 310
Query: 313 RRPEEKEPEKVNPQISDEKDEDEKEEKR-------RKTTPKEPTEKKMARAKT 358
+ E+++P + + SDE D +EEK+ K T K P KK A + +
Sbjct: 311 KAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSS 363
Score = 56.2 bits (134), Expect = 2e-07
Identities = 65/325 (20%), Positives = 132/325 (40%), Gaps = 35/325 (10%)
Query: 70 KEELSEEGYLAKVKSLLNKDLSLENG-AHAYNREVNGRLENGNQARSEARRVGMADANSP 128
+EE +G AK ++ K + L G A A E + E+ + E ++
Sbjct: 92 EEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVK 151
Query: 129 PKPLSKPRTPRRSKS---DGEAKRSRDPPASAS-QVTGI--RAEPSPSPRITRKSTRQTT 182
P+ + P+++KS D ++ +PP + ++T + +A+ P+ R + +
Sbjct: 152 PQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPK--- 208
Query: 183 ITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVAR-PLPAEEPERA 241
A G A S + SD+S EE+K ++ V ++ VA+ P+ A
Sbjct: 209 ----IANGKAASSSSSSSSSSSSDDS--EEEKAAATPKKTVPKKQVVAKAPVKAATTPTR 262
Query: 242 KSGTRTEKEEERDEKEEKRLRSQT---------KEPTPKQKLKEEPDREA---RAGVQAD 289
KS + + + +E+++K ++++ P PK+ L +P ++A + V++
Sbjct: 263 KSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESS 322
Query: 290 EDED------GDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKT 343
ED +E+ + ++ K P +K E + + ED++ +
Sbjct: 323 EDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAG 382
Query: 344 TPKEPTEKKMARAKTVMNSKTHPPK 368
T K + K K+ PK
Sbjct: 383 TTKNSSNKPAVTTKSPAVKPAAAPK 407
Score = 54.3 bits (129), Expect = 9e-07
Identities = 63/307 (20%), Positives = 111/307 (36%), Gaps = 57/307 (18%)
Query: 131 PLSKPRTPRRSKSDGEAKRSRD-----PPASASQVTGIRAEPSPSPRITRKSTRQTTITS 185
P++K + S SD E + PPA + V R P
Sbjct: 73 PVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPP---------------- 116
Query: 186 HFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGT 245
G A K E S +S + EED+ + ++ V + + A+ P ++ + + S +
Sbjct: 117 ----GKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKA-PPKKAKSSDSDS 171
Query: 246 RTEKEEERDEKEEKRL-----RSQTKEPTPKQKL--KEEPDREARAGVQADEDEDGDEKD 298
+ E+E + ++ ++ ++QTK P + K + A + + D+ +
Sbjct: 172 DSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSE 231
Query: 299 EKKHRSQPKDLAAKRRPEEKEPEKV------NPQISDEKDEDEKEEKRRKTTPKEPTEKK 352
E+K + PK K++ K P K S++ DE+EE+ K+P + K
Sbjct: 232 EEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQ------KKPMKNK 285
Query: 353 MARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGF 412
+V PPK G PP E Q D ++S
Sbjct: 286 PGPYSSVPPPSAPPPK------------KSLGTQPPKKAVEKQQPVESSEDSSDESDSSS 333
Query: 413 ESYEALP 419
E + P
Sbjct: 334 EEEKKPP 340
Score = 54.3 bits (129), Expect = 9e-07
Identities = 53/268 (19%), Positives = 108/268 (40%), Gaps = 40/268 (14%)
Query: 128 PPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHF 187
PPK + P+++ + S + + S + + P+ + K+T +
Sbjct: 299 PPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPP----- 353
Query: 188 AKGPAKRKPQEESERAKSDESIKEEDKDQ-------DEKRRRVTSRERVARPLPAEE--- 237
PAK+ + S+ + SD S +E + + VT++ +P A +
Sbjct: 354 ---PAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPV 410
Query: 238 -------PERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQ--- 287
+A S + E+ +E++ K++ + TK + P ++A G +
Sbjct: 411 GGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSS 470
Query: 288 ADEDEDGDEKDEKKH-----RSQPKDLAAKRRP------EEKEPEKVNPQISDEKDEDEK 336
+D D E++E+K + +P+ +A P ++ + E N SD+ E+E+
Sbjct: 471 SDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEE 530
Query: 337 EEKRRKTTPKEPTEK-KMARAKTVMNSK 363
E+ + K +P+ K A T N K
Sbjct: 531 EKLKGKGSPRPQAPKANGTSALTAQNGK 558
Score = 50.4 bits (119), Expect = 1e-05
Identities = 60/293 (20%), Positives = 114/293 (38%), Gaps = 12/293 (4%)
Query: 65 ETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMAD 124
E+ EE + A V K + A + + + ++A S+
Sbjct: 328 ESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNS 387
Query: 125 ANSPP----KPLSKPRT-PRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTR 179
+N P P KP P++ G+ +R +S+S+ +E + ++ +
Sbjct: 388 SNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKP 447
Query: 180 QTTITSHFAKGPAKRKPQEESERAK-SDESIKEEDKDQDEKRRRVTSRERVARPLPAEEP 238
+ T + + PAK+ PQ + + SD S EE++++ K ++VA +P
Sbjct: 448 KATAKAALSL-PAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKP 506
Query: 239 ERAKSG----TRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDG 294
AK G + + ++ E+EE++L+ + K A+ G A E+
Sbjct: 507 ASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEE 566
Query: 295 DEKDEKKHRSQPKDLAAKRRPE-EKEPEKVNPQISDEKDEDEKEEKRRKTTPK 346
+E+ +K K + K+R + E E PQ K + +RK K
Sbjct: 567 EEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEK 619
Score = 38.9 bits (89), Expect = 0.041
Identities = 31/141 (21%), Positives = 62/141 (43%), Gaps = 9/141 (6%)
Query: 133 SKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPA 192
SKP + ++ K++ S D +S + ++ + SP P+ K+ + +T+ K A
Sbjct: 504 SKPASAKKGKAESSNSSSSDD-SSEEEEEKLKGKGSPRPQAP-KANGTSALTAQNGKA-A 560
Query: 193 KRKPQEESERAKS------DESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTR 246
K +EE E+ K+ S+K+ +++ K +++ P P+R K R
Sbjct: 561 KNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKR 620
Query: 247 TEKEEERDEKEEKRLRSQTKE 267
R +EE + S+ +
Sbjct: 621 ASSPFRRVREEEIEVDSRVAD 641
Score = 36.2 bits (82), Expect = 0.27
Identities = 33/140 (23%), Positives = 60/140 (42%), Gaps = 14/140 (10%)
Query: 231 RPLPAEEP---ERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQ 287
R L A P + K + ++ E+ +E+EE + K P +++ P + A +
Sbjct: 66 RKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASE 125
Query: 288 A-------DEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKR 340
+ D+D++ D+K + + A + P +K + S +DE K +K
Sbjct: 126 SSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKP 185
Query: 341 RKT--TPKEPTE--KKMARA 356
+ T T K T+ K ARA
Sbjct: 186 KITPVTVKAQTKAPPKPARA 205
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 69.3 bits (168), Expect = 3e-11
Identities = 46/154 (29%), Positives = 82/154 (53%), Gaps = 34/154 (22%)
Query: 193 KRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE 252
K+K +E E +++E+ +EE+K+ K +R R+ E E+ K TEK +E
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRK---------EKEKKKKTKETEKRKE 54
Query: 253 RDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAK 312
++E+E+KR R + K+ KEE +RE + +E+E+ ++++E+K + + K
Sbjct: 55 KEEEEKKRKRKRKKK-------KEEEERE-----EEEEEEEEEKEEEEKEEGRRRKKKKK 102
Query: 313 RRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPK 346
RR +E+E EK K+++RRKT K
Sbjct: 103 RRRKEEEEEK-------------KKKRRRKTKKK 123
Score = 60.8 bits (146), Expect = 1e-08
Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 24/130 (18%)
Query: 236 EEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGD 295
+E E + TE+EEE++ K +++ + + KE K+K KE R+ + +
Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK-----------E 56
Query: 296 EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEE-------KRRKTTPKEP 348
E+++K+ R + K + R EE+E E+ +EK+E+EKEE K+R+ +E
Sbjct: 57 EEEKKRKRKRKKKKEEEEREEEEEEEE------EEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Query: 349 TEKKMARAKT 358
+KK R KT
Sbjct: 111 EKKKKRRRKT 120
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/95 (29%), Positives = 55/95 (57%), Gaps = 6/95 (6%)
Query: 189 KGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE 248
K K K +E+ ++ K+ E+ K ++K+++EK+R+ +++ EE ER + E
Sbjct: 30 KEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKK------KEEEEREEEEEEEE 83
Query: 249 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREAR 283
+E+E +EKEE R R + K+ K++ +E+ + R
Sbjct: 84 EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118
Score = 45.1 bits (105), Expect = 6e-04
Identities = 22/102 (21%), Positives = 59/102 (57%), Gaps = 3/102 (2%)
Query: 256 KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP 315
K++K+ + +T+E ++ +EE ++E G + ++ ++ ++ EKK +++ + ++
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKE---GKRKEKRKEKRKEKEKKKKTKETEKRKEKEE 57
Query: 316 EEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357
EEK+ ++ + +E++ +E+EE+ + +E E+ R K
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKK 99
Score = 44.3 bits (103), Expect = 0.001
Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 23/136 (16%)
Query: 139 RRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITS-------HFAKGP 191
++ K + E + + G R E R ++ ++T T K
Sbjct: 4 KKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRK 63
Query: 192 AKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEE 251
KRK ++E E + +E +EE+K+++EK EE R K + ++E
Sbjct: 64 RKRKKKKEEEEREEEEEEEEEEKEEEEK----------------EEGRRRKKKKKRRRKE 107
Query: 252 ERDEKEEKRLRSQTKE 267
E +EK++KR R K+
Sbjct: 108 EEEEKKKKRRRKTKKK 123
Score = 31.2 bits (69), Expect = 8.6
Identities = 16/52 (30%), Positives = 31/52 (59%), Gaps = 2/52 (3%)
Query: 312 KRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSK 363
K++ ++KE E+ ++E +E+E++E +RK KE ++K + KT K
Sbjct: 2 KKKKKKKETEETEE--TEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK 51
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 68.9 bits (167), Expect = 4e-11
Identities = 58/250 (23%), Positives = 110/250 (44%), Gaps = 22/250 (8%)
Query: 105 GRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIR 164
GRL + RS DA+ + + R +++ + + R RD R
Sbjct: 52 GRLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDRKRDRE---------R 102
Query: 165 AEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVT 224
R +QT I + +R+ Q+ ER + +E D+D++++R R T
Sbjct: 103 RRKEKETNRNRDREKQTEI-----ERDREREKQKGRERERDRGRERERDRDREKERERQT 157
Query: 225 SRERVARPLPAEEPERAKSGTRTEKEEERD-EKEEKRLRSQTKEPTPKQKLKEEPDREAR 283
++R + E ER + EK++ER+ E++ R R KE + + + R+ +
Sbjct: 158 EKDRDGQRETETERERDRE---REKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQ 214
Query: 284 AGVQADEDEDGD-EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK 342
Q + D +G+ E D ++ R + +D +R ++E ++ + + K E +KE K +K
Sbjct: 215 TERQRETDREGERETDRRRERQRDRDRGKER---DRERDRKEERKKERKKERKKERKEKK 271
Query: 343 TTPKEPTEKK 352
K +KK
Sbjct: 272 KEEKRREDKK 281
Score = 50.8 bits (120), Expect = 1e-05
Identities = 44/178 (24%), Positives = 79/178 (44%), Gaps = 13/178 (7%)
Query: 180 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 239
+ TI F++G R +ES R+ ++ D +R R RE+ + + +
Sbjct: 42 EVTIPLDFSRG---RLGSQESPRSWGLGQAHKDADGDDRQRERDRVREKTEKERDRDR-K 97
Query: 240 RAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDE 299
R + R EKE R+ EK+ + KQK +E RE G + + D D +++ E
Sbjct: 98 RDRERRRKEKETNRNRDREKQTEIERDREREKQKGRE---RERDRGRERERDRDREKERE 154
Query: 300 K---KHRSQPKDLAAKR---RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEK 351
+ K R ++ +R R EK+ E+ + D + + EKE +R+ ++ K
Sbjct: 155 RQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRK 212
Score = 35.0 bits (79), Expect = 0.60
Identities = 32/159 (20%), Positives = 60/159 (37%), Gaps = 11/159 (6%)
Query: 108 ENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEP 167
+ G + + R D + + + R + + E +R RD + +
Sbjct: 130 QKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDR 189
Query: 168 SPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDK------DQDEKRR 221
++ RQT + +RK Q E +R E +E D+ D+D +
Sbjct: 190 DRQRDTEKERERQTD-----RERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKE 244
Query: 222 RVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKR 260
R R+R + ER K +KEE+R E ++++
Sbjct: 245 RDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 68.9 bits (167), Expect = 4e-11
Identities = 45/190 (23%), Positives = 91/190 (47%), Gaps = 12/190 (6%)
Query: 180 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQD-----------EKRRRVTSRER 228
Q SH +K +R+ + + ER + ++ +E +K++ +KR R RER
Sbjct: 18 QMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER 77
Query: 229 VARPLPAEEPERA-KSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQ 287
+ + ER K + +KE+++ E++++ R + K+ K++ +E R R +
Sbjct: 78 KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137
Query: 288 ADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKE 347
+ + E+ +K R + + KR+ EE+E ++ + +K+ + KE + RK K+
Sbjct: 138 RRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKK 197
Query: 348 PTEKKMARAK 357
KK R K
Sbjct: 198 ERRKKKERKK 207
Score = 68.2 bits (165), Expect = 6e-11
Identities = 38/159 (23%), Positives = 81/159 (50%), Gaps = 8/159 (5%)
Query: 189 KGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE 248
+G ++K +++ ER K E ++E + Q ++RR R+R E +R + + +
Sbjct: 58 RGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKK 117
Query: 249 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKD 308
KE + E+E K+ R + ++ K+K ++E RE G + E+ KK + + ++
Sbjct: 118 KERKERERENKQRRERKRKKRRKKKRRKERKREKERGKR--------ERKRKKRKKEERE 169
Query: 309 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKE 347
+R +E++ E+ + + K E +KE +++K K+
Sbjct: 170 KKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Score = 60.1 bits (144), Expect = 2e-08
Identities = 50/228 (21%), Positives = 96/228 (42%), Gaps = 19/228 (8%)
Query: 132 LSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGP 191
+SKP T R S+ E +R R+ + R + +K R +
Sbjct: 25 ISKPCTQRESERKKE-RREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKERE 83
Query: 192 AKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEE 251
+RK + E ER K + K+ ++ Q +R R +ER +E ER R K +
Sbjct: 84 KQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER-------KERERENKQRRERKRK 136
Query: 252 ERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAA 311
+R +K+ ++ R + KE +++ +++ +E R ++K E+ + + K+
Sbjct: 137 KRRKKKRRKERKREKERGKRERKRKKRKKEER-----------EKKRERNRKERKKERER 185
Query: 312 KRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTV 359
K R E K+ K + E+ +D K +++ + P + TV
Sbjct: 186 KERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTV 233
Score = 57.4 bits (137), Expect = 1e-07
Identities = 41/177 (23%), Positives = 78/177 (44%), Gaps = 1/177 (0%)
Query: 127 SPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSH 186
S K + R R+ + + E KR R + R + R R+ R+
Sbjct: 34 SERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93
Query: 187 FAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTR 246
K ++K +E +R + + K+E K+++ + ++ R+R R ER + R
Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
Query: 247 TEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHR 303
++E +R +K +K R + +E K++ KE +E R + + E +K+ KK R
Sbjct: 154 GKRERKR-KKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDR 209
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 68.9 bits (167), Expect = 4e-11
Identities = 88/378 (23%), Positives = 155/378 (41%), Gaps = 45/378 (11%)
Query: 11 PTLAVPAISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEI------KNQLCDL 64
PT+ ++SLP RR D + TEKE E +E +TE KN D
Sbjct: 123 PTITDASLSLPS--RRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDA 180
Query: 65 ETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMAD 124
E ++++ EE K K G+ N+ E +++ E + + +
Sbjct: 181 EENKKEDKEKEEEEEEKPK----------RGSIGENQVEVMVEEKTTESQEETVVMSLKN 230
Query: 125 AN-SPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTI 183
S +P + + S ++ + ++ R E RI K+ + I
Sbjct: 231 GQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERI--KAEQDKKI 288
Query: 184 TSHFAKGPAKRKP---QEESERAKSDESIKEEDKDQDEKRRRVTSRERVA----RPLPAE 236
A+ A+ K + E A+ E ++EE+K E+R+R+ E+ A + + E
Sbjct: 289 ADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEE 348
Query: 237 EPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREAR---------AGVQ 287
E A+ R ++EE+R +E +R R++ +E ++ K E + G +
Sbjct: 349 EKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEK 408
Query: 288 ADEDEDGDEKDEKKHRSQPKDLAA-KRRPEEK------EPEKVNPQISDEKDEDEKEEKR 340
++ +G +EKK + A K++ EEK + EK+ K E+ K+EK
Sbjct: 409 VEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKI 468
Query: 341 RK-TTPKEPTEKKMARAK 357
+K PKE + M R K
Sbjct: 469 KKDKEPKEEVKSFMDRKK 486
Score = 64.7 bits (156), Expect = 7e-10
Identities = 74/342 (21%), Positives = 137/342 (40%), Gaps = 28/342 (8%)
Query: 54 QTEIKNQLCDLETKLRKEELSEEGYLAKVK-------SLLNKDLSLENGAHAYNREVNGR 106
Q E ++ LE R+EE ++ ++ ++ + LSL + + N
Sbjct: 87 QVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET 146
Query: 107 LENGNQARSEARRVGMADANSPPKPLSKP--RTPRRSKSDGEAKRSRDPPASASQVTGIR 164
E ++ S R + + + K K R +K + + K + G
Sbjct: 147 TEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGEN 206
Query: 165 AEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESI------KEEDKDQDE 218
T +S +T + S + +P++E ER + + I +EEDK++ E
Sbjct: 207 QVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE 266
Query: 219 KRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE--------RDEKEEKRLRSQTKEPT- 269
R E R ++ + A R E EE+ R+ +E +R+R + K
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE 326
Query: 270 PKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKR---RPEEKEPEKVNPQ 326
+Q++KEE R A + E+E ++ ++ + + K A +R R EE+E KV Q
Sbjct: 327 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386
Query: 327 ISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPK 368
+++ E++K + E E+K+ K V K K
Sbjct: 387 KRNKQLEEKKHAMQETKIKGEKVEQKI-EGKWVNEKKAQEDK 427
Score = 43.1 bits (100), Expect = 0.002
Identities = 42/199 (21%), Positives = 86/199 (43%), Gaps = 21/199 (10%)
Query: 197 QEESERAKSDESIKEE--DKDQDEKRRRVTSRERV--ARPLPAEEPERAKSGTRTEKEEE 252
+EE+ R + + +E K ++E +VT + V +P EE + + T+ E ++E
Sbjct: 34 EEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDE 93
Query: 253 ---------RDEKEEKRL-----RSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKD 298
R+E+ +KRL R + +PT P R + +E + +EK
Sbjct: 94 AAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 153
Query: 299 E---KKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMAR 355
E +++ + + K + + + D++ E+E+EEK ++ + E + M
Sbjct: 154 ESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVE 213
Query: 356 AKTVMNSKTHPPKCIQCGQ 374
KT + + ++ GQ
Sbjct: 214 EKTTESQEETVVMSLKNGQ 232
Score = 42.7 bits (99), Expect = 0.003
Identities = 48/259 (18%), Positives = 109/259 (42%), Gaps = 33/259 (12%)
Query: 173 ITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARP 232
+ R+ TIT P++R +++ A+++ + KEE + ++R + E V +
Sbjct: 115 LERQKEFDPTITDASLSLPSRRM---QNDTAENETTEKEEKSESRQERYEIEETETVTKS 171
Query: 233 LPAEEPERAKSGTRTEKEEERDEKEEKRLRS---------------QTKEPTPKQKLK-- 275
+ A+ + +KE+E +E+E+ + S +++E T LK
Sbjct: 172 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNG 231
Query: 276 ----EEPDREARAGVQADE---DEDGDEKDEKKHRSQPKDLAAKRRPEEK--EPEKVNPQ 326
EEP +E +DE E +E+D+++ ++ L A+ R K + +K+ +
Sbjct: 232 QISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADE 291
Query: 327 IS----DEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLK 382
+ +EK ++ E+R + E++ A+ K + + Q + + + +
Sbjct: 292 RARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKR 351
Query: 383 YGQHPPDAVDEPQMLTNEK 401
+ +E + E+
Sbjct: 352 AAEERQRIKEEEKRAAEER 370
Score = 41.6 bits (96), Expect = 0.006
Identities = 36/149 (24%), Positives = 59/149 (39%), Gaps = 11/149 (7%)
Query: 215 DQDEKRRRVTSRERVARPLPAE----------EPERAKSGTRTEKEEERDEKEEKRLRSQ 264
D E+RR + ++R L AE E E A+ R ++E +K+E+ Q
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 265 TKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEK-V 323
+ PD EA+ + E DE + ++ ++ KR E E +K
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 324 NPQISDEKDEDEKEEKRRKTTPKEPTEKK 352
+P I+D + T E TEK+
Sbjct: 122 DPTITDASLSLPSRRMQNDTAENETTEKE 150
Score = 38.9 bits (89), Expect = 0.041
Identities = 76/363 (20%), Positives = 141/363 (38%), Gaps = 59/363 (16%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
R+R+K+ E+ + E++ +KE+ E Q + + E + R +EE AKV+
Sbjct: 328 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRAR--AEEEEKAKVEE 385
Query: 85 LLNKDLSLENGAHAYN----------REVNGRLENGNQARSEARRVGMADANSPPKPLS- 133
++ LE HA +++ G+ N +A+ + + + K
Sbjct: 386 Q-KRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKV 444
Query: 134 ----------KPRTPRRSKSDGEAKRSRDPPASASQVT----GIRAEPSPSPRITRKSTR 179
KP + D + K+ ++P G S + +
Sbjct: 445 QAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLK 504
Query: 180 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 239
T T G A +++ A+ ++ + ++ +RRR + L ++ E
Sbjct: 505 HTENTFSRPGGRAS----VDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQE 560
Query: 240 RAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDE 299
A E EE + ++EE+R + +E KQ EE DR+ R E++E
Sbjct: 561 AA-----LELEELKKKREERRKVLEEEEQRRKQ---EEADRKLR------------EEEE 600
Query: 300 KKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTV 359
K+ + K+ +RR E E + P+ D +D+K K TPK + K RA+ +
Sbjct: 601 KR---RLKEEIERRRAEAAEKRQKMPE--DGLSDDKKPFK--CFTPKGSSLKIEERAEFL 653
Query: 360 MNS 362
S
Sbjct: 654 NKS 656
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 68.2 bits (165), Expect = 6e-11
Identities = 83/382 (21%), Positives = 160/382 (41%), Gaps = 46/382 (12%)
Query: 26 RRLKDLERDSLTEKECVKEKLNLLHEFLQTE--IKNQLCDLETKLRKEELSEEGYLAKVK 83
RR + L R+ +E +E+ HE + E +K + + L++EE +E + K
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKP-RTPRRSK 142
L +D E E R E + + RR K + R +R +
Sbjct: 474 QQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLR 533
Query: 143 SDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESER 202
S+ + +R ++ ++ E R+ R KR+ + +R
Sbjct: 534 SEQQLRREQEERREQL----LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Query: 203 AKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEP--ERAKSGTRTEKEEER------- 253
K ++ + E + + E+ R+ ER + L EEP ER + ++E++EER
Sbjct: 590 LKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRR 649
Query: 254 --DEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED-----------------G 294
E+ E+RL+ + +E +Q+LK E + E R A+E+++
Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE 709
Query: 295 DEKDEKKHR--SQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEK-------EEKRRKTTP 345
E D ++ + S+P+ +RR +E+E ++ + + E+E+ EE+RR T
Sbjct: 710 SEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTW 769
Query: 346 KEPTEKKMARAKTVMNSKTHPP 367
+ E+K R + ++++ PP
Sbjct: 770 QWQAEEKSERGRQRLSAR--PP 789
Score = 63.5 bits (153), Expect = 2e-09
Identities = 69/340 (20%), Positives = 143/340 (42%), Gaps = 27/340 (7%)
Query: 33 RDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSL 92
R +L K ++E+L + LQ E + +L E + R+ + E Y + + ++ L
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEE-EEELQREEREKRRRQEQERQYREEEQLQQEEEQLL 944
Query: 93 ENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRD 152
RE R E Q R + + + +P + R R K E + ++
Sbjct: 945 RE-----EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQE 999
Query: 153 PPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEE 212
+ R + +K Q + KR+ QE + + +E +++E
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059
Query: 213 DKDQDEKRRRVTSRERVARP-------------LPAEEPERAKSGTRTE--KEEERDEKE 257
++ + R R+ + R L EEPE+ + R +EEE ++E
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 258 EKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEE 317
E++L + +E +Q+L+ + E VQ +E++ E+ EK+ R + ++ EE
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEE--VQQEEEQLLREEPEKRRRQE----LERQYREE 1173
Query: 318 KEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357
+E ++ Q+ E+ E ++E+ R+ +E +++ + +
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Score = 62.8 bits (151), Expect = 3e-09
Identities = 66/334 (19%), Positives = 147/334 (44%), Gaps = 37/334 (11%)
Query: 24 VRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVK 83
+RR+ ++ R+ E+ +E+ E + +++ + + + R+++L E + +
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRRE----QEERREQQLRREQEEERRE 361
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKS 143
L ++ E RE R E + + RR + + R ++ +
Sbjct: 362 QQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 421
Query: 144 DGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERA 203
+ + +R ++ + R E R+ R+ + K +EE+ER
Sbjct: 422 EQQLRREQEEERHEQKHEQERREQ----RLKREQEERRDWL----------KREEETERH 467
Query: 204 KSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKE--EERDEKEEKRL 261
+ + ++ +DQ+E+RR R L EE ER + R E++ E++E+ E+RL
Sbjct: 468 EQERRKQQLKRDQEEERRE--------RWLKLEEEERREQQERREQQLRREQEERREQRL 519
Query: 262 RSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPE 321
+ Q +E +Q+L+ E ++ R + ++ ++EK+ + ++ KR EE+ +
Sbjct: 520 KRQEEEERLQQRLRSE--QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577
Query: 322 KVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMAR 355
+ K E+E+ ++R K +E E+++ R
Sbjct: 578 LL-------KREEERRQQRLKREQEERLEQRLKR 604
Score = 61.6 bits (148), Expect = 6e-09
Identities = 70/355 (19%), Positives = 147/355 (41%), Gaps = 26/355 (7%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEE------------ 72
RR L +L R EK+ +++ Q E + + ET LRKEE
Sbjct: 212 RRELLELRRKGREEKQ--QQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 73 -LSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKP 131
L EE +++ L ++L E ++ R + + + E RR + +
Sbjct: 270 ELQEEE--EQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Query: 132 LSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGP 191
+ R + E + R+ Q R + + + +Q +
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 192 AKRKPQE--ESERAKSDESIKEED---KDQDEKRRRVTSRERVA-RPLPAEEPERAKSGT 245
R+ Q+ ++ + ++ ++ E ++Q +R + RE+ R E ER +
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRL 447
Query: 246 RTEKEEERDEKEEKRLRSQTKEPTPKQKLK---EEPDREARAGVQADEDEDGDEKDEKKH 302
+ E+EE RD + + + ++ KQ+LK EE RE ++ +E + E+ E++
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQL 507
Query: 303 RSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357
R + ++ +R ++E E++ ++ E+ ++E+RR+ K EK++ + +
Sbjct: 508 RREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Score = 57.8 bits (138), Expect = 9e-08
Identities = 53/251 (21%), Positives = 124/251 (49%), Gaps = 38/251 (15%)
Query: 191 PAKRKPQEESERAKSDESIKEED----KDQDEKRRRVTSRERVARPLPAEEPERAKSGTR 246
P KR+ QE ++ + +E +++E+ +++ EKRRR E R K +
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW----------ERQYRKKDELQ 1027
Query: 247 TEKEEE-RDEKEEKRLRSQTKEPTPKQKLKEEPD------REARAGVQAD----EDEDGD 295
E+E+ R+E+E++RL+ + ++ +++L++E + RE R + + ++E+
Sbjct: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQ 1087
Query: 296 EKDEKKHRSQPKDLAAKRRPEEKEPE-KVNPQISDEKDE---DEKEEKRRKTTPKEPTEK 351
+++E+ R +P+ KRR +E+E + + ++ E+++ +E+E++RR+ ++ E+
Sbjct: 1088 QEEEQLLREEPE----KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREE 1143
Query: 352 KMARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESG 411
+ + + + P K + + + +Y + +E Q+L E+ E
Sbjct: 1144 EEVQQEEEQLLREEPEK-----RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ 1198
Query: 412 FESYEALPQHK 422
+ E L + K
Sbjct: 1199 YREEEELQRQK 1209
Score = 57.0 bits (136), Expect = 1e-07
Identities = 61/310 (19%), Positives = 131/310 (42%), Gaps = 37/310 (11%)
Query: 56 EIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNR----EVNGRLENGN 111
E K CD + L ++ EE + +D LE R E L G
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQ----RRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE 152
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSP 171
+ + R+ D + L + R + + + A+ + G E P
Sbjct: 153 EQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQ-----LQSCKGHETEEFPD- 206
Query: 172 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVAR 231
+ R+ + KG R+ +++ R + D +EE++ + KR V +E
Sbjct: 207 ---EEQLRRRELLELRRKG---REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEE--E 258
Query: 232 PLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQ---A 288
L EEP+R + E E+EE+ + + +E +++ +E+ + R Q
Sbjct: 259 KLQEEEPQR---------QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 289 DEDEDGDEKDEKKHRSQPKDLAAKRRPEE---KEPEKVNPQISDEKDEDEKEEKRRKTTP 345
E+E ++++E++ + + ++ +RR ++ ++ E+ Q+ E++E+ +E++ R+
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 346 KEPTEKKMAR 355
+E E+++ R
Sbjct: 370 EERREQQLRR 379
Score = 54.7 bits (130), Expect = 7e-07
Identities = 79/403 (19%), Positives = 166/403 (41%), Gaps = 51/403 (12%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
+RR ++ ER + E +E+ LL E + K +L + E + R+EE ++ + +
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREERE---KRRLQERERQYREEEELQQ----EEEQ 1062
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSD 144
LL ++ RE R E Q R E +P RR + +
Sbjct: 1063 LLGEE-----------RETRRRQELERQYRKEEE----LQQEEEQLLREEPEKRRRQERE 1107
Query: 145 GEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSH----FAKGPAKRKPQEES 200
+ + + Q+ E + R+ + + + P KR+ QE
Sbjct: 1108 RQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Query: 201 ERAKSDESIKEEDKD--QDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERD---- 254
+ + +E +++E++ ++E+ +R RER R EE +R K R E++R
Sbjct: 1168 RQYREEEELQQEEEQLLREEQEKRRQERERQYRE--EEELQRQKRKQRYRDEDQRSDLKW 1225
Query: 255 ----EKE----EKRLRSQTKEPTPKQKLKEEP--DREARAGVQ--ADEDEDGDEKDEKKH 302
EKE + ++ + +E ++L++ DR+++ +Q E ++ D + E++
Sbjct: 1226 QWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR- 1284
Query: 303 RSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEK----EEKRRKTTPKEPTEKKMARAKT 358
R Q +D + + E+ + D K ++EK EE+ K +E K +
Sbjct: 1285 RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL 1344
Query: 359 VMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEK 401
+ + P + + + + +L++ + ++E Q L ++
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQE 1387
Score = 53.9 bits (128), Expect = 1e-06
Identities = 46/180 (25%), Positives = 86/180 (47%), Gaps = 20/180 (11%)
Query: 186 HFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGT 245
++A G A +E+ R ES+ ++ + + E +RR R+R EEP + +
Sbjct: 86 YYALGQATGLDEEKRARCDGKESLLQDRRQE-EDQRRFEPRDRQLE----EEPGQRRRQK 140
Query: 246 RTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEK-------- 297
R E+E E E EE+ + + E +Q+ EE R+ + + +E +E+
Sbjct: 141 RQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHE 200
Query: 298 ------DEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEK 351
+E+ R + +L K R EEK+ ++ Q ++E+EKE ++R+T ++ EK
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGR-EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK 259
Score = 53.5 bits (127), Expect = 2e-06
Identities = 80/405 (19%), Positives = 161/405 (39%), Gaps = 45/405 (11%)
Query: 21 PDDVRRR--LKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGY 78
P++ RR+ LK E++ +++ +E+ + L+ E + + + K EE E
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE 684
Query: 79 LA---------KVKSLLNK-DLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSP 128
LA ++KS + K LE+ A A +V R R +
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 129 PKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGI-RAEPSPSPRITRKSTRQTTITSHF 187
+ R + + E +R A + + R S P + + RQ
Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ 804
Query: 188 AKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRT 247
+ +EE E+ + +E++ E+ ++ RER + E+ + R
Sbjct: 805 QREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRR 864
Query: 248 EKEEERDEK------EEKRLRSQT--KEPTPKQKLKEEPDREARAGVQADEDEDGDEKDE 299
+E+ RD+K EE++ R T +P +++L++E +Q +E+E E+ E
Sbjct: 865 SQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL-----LQEEEEELQREERE 919
Query: 300 KKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDE---DEKEEKRRKTTPKEPTEKKMARA 356
K +RR E++ + Q+ E+++ +E+E++RR+ ++ + K +
Sbjct: 920 K-----------RRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQ 968
Query: 357 KTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEK 401
K P K + + + KY + +E Q+L E+
Sbjct: 969 KEEQLLGEEPEK-----RRRQEREKKYREEEELQQEEEQLLREER 1008
Score = 53.1 bits (126), Expect = 2e-06
Identities = 76/348 (21%), Positives = 150/348 (43%), Gaps = 34/348 (9%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
+RR ++LER E+E +E+ LL E + K + +LE + R+EE ++ + +
Sbjct: 1130 KRRRQELERQYREEEEVQQEEEQLLREEPE---KRRRQELERQYREEEELQQ----EEEQ 1182
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSD 144
LL + E RE R E Q + +R D S K +P + +
Sbjct: 1183 LLRE----EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDN 1238
Query: 145 GEAKRSRDPPA----SASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEES 200
+ R+ SQ+ +++ + + R + + P+EE
Sbjct: 1239 KVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQ 1298
Query: 201 -ERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEER--DEKE 257
ER + E+ + + K Q+EK ++ ER EE R + R +EEE+ E+E
Sbjct: 1299 LEREEQKEAKRRDRKSQEEK--QLLREER-------EEKRRRQETDRKFREEEQLLQERE 1349
Query: 258 EKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED--GDEKDEKKHRSQPKDLAAKRRP 315
E+ LR Q ++ +K +EE R G + E+E ++ E+K + + L + R
Sbjct: 1350 EQPLRRQERD----RKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE 1405
Query: 316 EEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSK 363
++ ++ + + +E+ + ++E+ RK +E ++ R + + +
Sbjct: 1406 QQLRQDR-DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452
Score = 52.4 bits (124), Expect = 4e-06
Identities = 68/331 (20%), Positives = 139/331 (41%), Gaps = 37/331 (11%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLC------DLETKLRKEELSEEGY 78
+RR ++LER E+E +E+ LL E + + + +L+ + RK+ +E
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQ 1219
Query: 79 LAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTP 138
+ +K + EN GR EN + E ++ + + L +
Sbjct: 1220 RSDLKWQWEPEK--ENAVRDNKVYCKGR-ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276
Query: 139 RRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQE 198
R + + + RD + R E + R RKS + + + + +E
Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLE-REEQKEAKRRDRKSQEEKQLL--------REEREE 1327
Query: 199 ESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE--- 255
+ R ++D +EE++ E+ + R+ R EE + G + +EE+R
Sbjct: 1328 KRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQE 1387
Query: 256 ------KEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDL 309
KEE++LR Q +E Q+L+++ DR+ R E+E + E+ + + ++
Sbjct: 1388 RERKFLKEEQQLRCQERE----QQLRQDRDRKFR------EEEQQLSRQERDRKFREEEQ 1437
Query: 310 AAKRRPEEKEPEKVNPQISDEKDEDEKEEKR 340
+R+ E++ + Q+ E+ +EE++
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQ 1468
Score = 51.2 bits (121), Expect = 8e-06
Identities = 77/376 (20%), Positives = 154/376 (40%), Gaps = 44/376 (11%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEE--LSEEGYLAKV 82
+RR ++ ER E+E +E+ LL E + K + +LE + R+EE EE L +
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREERE---KRRRQELERQYREEEEVQQEEEQLLRE 1156
Query: 83 KSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSK 142
+ + LE Y E + E R E + + R R+ +
Sbjct: 1157 EPEKRRRQELER---QYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQR 1213
Query: 143 SDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESER 202
E +RS ++ + P + R + + R+ ++ R
Sbjct: 1214 YRDEDQRS-----------DLKWQWEPEKE---NAVRDNKVYCKGRENEQFRQLEDSQLR 1259
Query: 203 AKSDESI------KEEDKDQDEKRRRVTSRER---VARPLPAEEPERAKSGTRTEKEEE- 252
+ + +++++D++++RRR R+R L EE + AK R +EE+
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQ 1319
Query: 253 --RDEKEEKRLRSQT-----KEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 305
R+E+EEKR R +T +E Q+ +E+P R + E+E ++ +K +
Sbjct: 1320 LLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEE 1379
Query: 306 PKDLAAKRRPEE--KEPEKVNPQISDEK---DEDEKEEKRRKTTPKEPTEKKMARAKTVM 360
+ L + R + KE +++ Q +++ D D K + + ++ ++K + +
Sbjct: 1380 EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV 1439
Query: 361 NSKTHPPKCIQCGQYL 376
+ K ++ Q L
Sbjct: 1440 RRQERERKFLEEEQQL 1455
Score = 50.8 bits (120), Expect = 1e-05
Identities = 74/351 (21%), Positives = 146/351 (41%), Gaps = 49/351 (13%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRK-EELSEEGYLAKVK 83
+RR ++ E+ E+E +E+ LL E + K + + E + RK +EL +E +
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREERE---KRRRQEWERQYRKKDELQQEE-----E 1031
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKS 143
LL ++ RE E Q R E + L + R RR +
Sbjct: 1032 QLLREE-----------REKRRLQERERQYREEEEL-----QQEEEQLLGEERETRR-RQ 1074
Query: 144 DGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERA 203
+ E + ++ + +R EP R R+ + + R+ +E+ R
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 204 KSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRS 263
+ + +EE++ Q E+ + + R E R + + E+E+ E++EKR +
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194
Query: 264 QTKEPTPKQKLKEEPDREARAGVQADEDEDGDEK----DEKKHRSQPKDLAAKRRPEEKE 319
+ ++ + +EE R+ R DED+ D K EK++ + + K R E+
Sbjct: 1195 RERQ----YREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Query: 320 PEKVNPQISD------------EKDEDEKEEKRRKTTPKE---PTEKKMAR 355
+ + Q+ D E+ E ++E++RR+ ++ P E+++ R
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLER 1301
Score = 50.4 bits (119), Expect = 1e-05
Identities = 40/184 (21%), Positives = 87/184 (47%), Gaps = 26/184 (14%)
Query: 179 RQTTITSHFAKGPAKRKPQEESERA--KSDESIKEEDKDQDEKRRRVTSRERVARPLPAE 236
RQ T + RK EE + + ++ ++ +++D+ + +ER + L ++
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 237 EPERAKSGTRTEKEEERDEKEEKRLRSQTKE------------PTPKQKLKEEPDREARA 284
E +R E+E+ R E+EE++LR Q ++ +Q+L++E DR+ RA
Sbjct: 1792 ESDRKFR----EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRA 1847
Query: 285 GVQ--------ADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEK 336
Q +E E E+++K+ + + + L + +++ E+ + Q+ + K ++ K
Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGK 1907
Query: 337 EEKR 340
R
Sbjct: 1908 GHGR 1911
Score = 49.7 bits (117), Expect = 2e-05
Identities = 43/170 (25%), Positives = 87/170 (51%), Gaps = 18/170 (10%)
Query: 197 QEESERAKSDESIKEE----DKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEE- 251
QE+ ER +S E +++ +++ KRRR T A+P E+ + + + E+EE
Sbjct: 857 QEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL---YAKPALQEQLRKEQQLLQEEEEEL 913
Query: 252 ---ERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKD 308
ER+++ + Q +E Q+ +E+ RE R + E E KD+K + + +
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973
Query: 309 LA---AKRRPEEKEPE-KVNPQISDEKDE---DEKEEKRRKTTPKEPTEK 351
L KRR +E+E + + ++ E+++ +E+E++RR+ ++ +K
Sbjct: 974 LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKK 1023
Score = 48.1 bits (113), Expect = 7e-05
Identities = 38/182 (20%), Positives = 84/182 (46%), Gaps = 26/182 (14%)
Query: 197 QEESERAKSDESIKEEDKD--QDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE-- 252
+++ R + D +EE++ + E+ R+ E+ R E R + R E E+E
Sbjct: 1681 EQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQL 1740
Query: 253 ---------------RDEKEEKRLRSQTKEP--TPKQKLKEEPDREARAGVQAD-----E 290
R E+EE++LR Q ++ +++L++E + + ++D E
Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREE 1800
Query: 291 DEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 350
++ E++E++ R Q +D + E+ + E+ ++ E+D + E++ T K E
Sbjct: 1801 EQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860
Query: 351 KK 352
++
Sbjct: 1861 EQ 1862
Score = 46.6 bits (109), Expect = 2e-04
Identities = 35/163 (21%), Positives = 79/163 (48%), Gaps = 14/163 (8%)
Query: 193 KRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE 252
+R+ + + R D +EE++ + E+ + SR+ R EE + R +++E
Sbjct: 1541 RRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQK-----VRRQEQER 1595
Query: 253 RDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAK 312
+ ++E++LR Q + Q+L++E DR+ R DE + ++++ HR + +
Sbjct: 1596 KFMEDEQQLRRQEGQ----QQLRQERDRKFR----EDEQLLQEREEQQLHRQERDRKFLE 1647
Query: 313 RRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMAR 355
P+ + E+ Q+ ++D +EE++ +E ++ R
Sbjct: 1648 EEPQLRRQER-EQQLRHDRDRKFREEEQLLQEGEEQQLRRQER 1689
Score = 45.1 bits (105), Expect = 6e-04
Identities = 65/348 (18%), Positives = 141/348 (40%), Gaps = 34/348 (9%)
Query: 43 KEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNRE 102
+E+ L E + ++ Q D + +L ++++ + K + L + G +E
Sbjct: 1558 REEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMED-EQQLRRQEGQQQLRQE 1616
Query: 103 VNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTG 162
+ + Q E + K L + RR + + + + RD +
Sbjct: 1617 RDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 163 IRAEPSPSPRITR--------KSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDK 214
E R R + R+ F + + + QE + + +E +++E +
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
Query: 215 DQD----EKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE--RDEKEEKRLRSQTKEP 268
+ E+ R++ E++ RP E+ R + R +EEE R E+EE++LRSQ +
Sbjct: 1737 QEQLRRQERYRKILEEEQL-RPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDR 1795
Query: 269 T--PKQKLKEEPDREARAGVQAD-----EDEDGDEKDEKKHRSQPKD----------LAA 311
+++L++E + + Q D E+E +++++ Q +D
Sbjct: 1796 KFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQE 1855
Query: 312 KRRPEEKEP-EKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKT 358
K R EE+E ++ + E++ +EE R+ +E +++ K+
Sbjct: 1856 KSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKS 1903
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/160 (21%), Positives = 76/160 (47%), Gaps = 13/160 (8%)
Query: 217 DEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEE------RDEKEEKRLRSQTKEPTP 270
+EKR R +E + + EE +R + EEE + +E++R ++ +E +
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 271 KQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQP----KDLAAKRRPEEKEPEKVNPQ 326
KQ+ E+ DR+ R + ++ E++E++ + K + P+E++ +
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELL 216
Query: 327 ISDEKDEDEKEEKRRKTTPK---EPTEKKMARAKTVMNSK 363
K +EK+++RR+ + E EK+ + +TV+ +
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE 256
Score = 43.1 bits (100), Expect = 0.002
Identities = 74/391 (18%), Positives = 157/391 (40%), Gaps = 71/391 (18%)
Query: 20 LPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYL 79
L + ++ K +R S EK+ ++E + E K + + + K R+EE
Sbjct: 1299 LEREEQKEAKRRDRKSQEEKQLLRE---------EREEKRRRQETDRKFREEE------- 1342
Query: 80 AKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPR 139
++ + L + + E E G + E +R+ + K L + + R
Sbjct: 1343 QLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERER--KFLKEEQQLR 1400
Query: 140 RSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEE 199
+ + + ++ RD + R E R + R+ F + + + QE
Sbjct: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR-QER 1459
Query: 200 SERAKSDESIKEEDKDQ-------------DEKRRRVTSRERVARP--LPAEEPE----- 239
+ + +E + +E ++Q +E++ R R+R R L ++EPE
Sbjct: 1460 HRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE 1519
Query: 240 ----------------------RAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEE 277
R + G + ++ +R +EE++LR + +E +Q ++E
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE---QQLSRQE 1576
Query: 278 PDREAR---AGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDED 334
DR+ R V+ E E +DE++ R Q ++ + K E + Q+ E++E
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFRE--DEQLLQEREEQ 1634
Query: 335 E--KEEKRRKTTPKEPTEKKMARAKTVMNSK 363
+ ++E+ RK +EP ++ R + + + +
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDR 1665
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 66.6 bits (161), Expect = 2e-10
Identities = 53/263 (20%), Positives = 117/263 (44%), Gaps = 9/263 (3%)
Query: 102 EVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVT 161
+++G NG + R + G S + S R+ RS+ +++SR S+
Sbjct: 159 KLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSR---HSRKSRSRSGSSKSSH 215
Query: 162 GIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRR 221
S S +R +R + + +K R P +E R++S + K K +D+
Sbjct: 216 SKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEE 275
Query: 222 RVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR- 280
++ + + V +P + P R KS +++ + EE++ S ++ + ++ L++ R
Sbjct: 276 KIQNNDNVGKP-KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRS 334
Query: 281 EARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKR 340
++ G ++ KD++K R + ++ + R + E+ + ++D K+
Sbjct: 335 RSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKR-GSKRDSKAGSSKK 393
Query: 341 RKTTPKEPTEKKMARAKTVMNSK 363
+K KE T++ +R+ + SK
Sbjct: 394 KK---KEDTDRSQSRSPSRSVSK 413
Score = 61.6 bits (148), Expect = 6e-09
Identities = 56/276 (20%), Positives = 118/276 (42%), Gaps = 17/276 (6%)
Query: 99 YNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASAS 158
++R+ R + + S++R + + S K S+ ++ RSK + S++ S S
Sbjct: 200 HSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRS 259
Query: 159 QVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDE 218
G ++ + K + ++ P++ K + +S R++S E EE+K
Sbjct: 260 HSAG-KSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKS-RSRSQERRVEEEKRGSV 317
Query: 219 KRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPT-PKQKLKEE 277
R R S+E+ R + R+K G+R+ K++++ R +++E + + + + +
Sbjct: 318 SRGR--SQEKSLRQ--SRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSK 373
Query: 278 PDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKE 337
+R + G + D + G K +KK + + R KE E + S + E E
Sbjct: 374 SERSRKRGSKRD-SKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESE 432
Query: 338 ---------EKRRKTTPKEPTEKKMARAKTVMNSKT 364
+ R + +P +R+++ SKT
Sbjct: 433 NAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKT 468
Score = 46.6 bits (109), Expect = 2e-04
Identities = 41/161 (25%), Positives = 72/161 (44%), Gaps = 8/161 (4%)
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSP 171
Q+RS +R G + + S + SK + R +S E+ RSR S S+ + R S
Sbjct: 329 QSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES-RSRSRSRSKSERSRKRGSKRDSK 387
Query: 172 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQD------EKRRRVTS 225
+ K ++ ++ P+ R +E E AKS+ S +E + + E R R S
Sbjct: 388 AGSSKKKKKEDTDRSQSRSPS-RSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRS 446
Query: 226 RERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTK 266
+ LP+E R+KS ++T + + R S+++
Sbjct: 447 NSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSR 487
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 65.9 bits (159), Expect = 3e-10
Identities = 58/256 (22%), Positives = 99/256 (38%), Gaps = 13/256 (5%)
Query: 111 NQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPS 170
++ R+ R +D++ PK + PRRS+S G + + R P S T E P
Sbjct: 1606 DKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS-GSSSKGRGPSPEGSSSTESSPEHPPK 1664
Query: 171 PRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDK---DQDEKRRRVTSRE 227
R R+ +R + ++ P +R+ S + + E R R R
Sbjct: 1665 SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH 1724
Query: 228 R----VARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDRE-A 282
R V+ P PAE+ S R R + +R RS + +P Q+ + RE
Sbjct: 1725 RRSPSVSSPEPAEKSR--SSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782
Query: 283 RAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK 342
R + D ++ RS+ + +RR +P + + + R
Sbjct: 1783 RTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRS 1842
Query: 343 TTPKEPTEKKMARAKT 358
TP PT +K +R++T
Sbjct: 1843 RTP--PTSRKRSRSRT 1856
Score = 51.2 bits (121), Expect = 8e-06
Identities = 46/176 (26%), Positives = 79/176 (44%), Gaps = 10/176 (5%)
Query: 111 NQARSEARRVGMADANSPPKP-LSKPRTPRRSKSDGEAKRSRDPPASAS-QVTGIRAEPS 168
+++R+ ARR G + + +P + S+ RTPRR +S + R S + Q G S
Sbjct: 669 SRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSS 728
Query: 169 PSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRER 228
+R S R++ S P +K + S R++S S + + K + RR ++
Sbjct: 729 ERKNKSRTSQRRSRSNS----SPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSP 784
Query: 229 VARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARA 284
+ P R++SG+ K + R R + P PKQK K P R++ +
Sbjct: 785 CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR---SSSSPPPKQKSK-TPSRQSHS 836
Score = 51.2 bits (121), Expect = 8e-06
Identities = 47/234 (20%), Positives = 83/234 (35%), Gaps = 19/234 (8%)
Query: 136 RTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRI-TRKSTRQTTITSHFAKGPAKR 194
RTP +S + + D SAS ++ SP + TR RQ + + + +K
Sbjct: 1530 RTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589
Query: 195 KPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSG---------- 244
+ R+ S +K++ + + S P P P R++SG
Sbjct: 1590 RLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSP 1649
Query: 245 ---TRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKK 301
+ TE E K R P PK K + P R + + + K
Sbjct: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRS-----SRSSPELTRKARLS 1704
Query: 302 HRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMAR 355
RS+ + + R + +P +S + ++ RR+ + P K +R
Sbjct: 1705 RRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758
Score = 48.9 bits (115), Expect = 4e-05
Identities = 54/241 (22%), Positives = 93/241 (38%), Gaps = 34/241 (14%)
Query: 121 GMADANSPPKPLSKPRTPR-RSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTR 179
G ++ +S P+P + P+TPR RS+S P + +T R + +K+
Sbjct: 1476 GRSECDSSPEPKALPQTPRPRSRSPS------SPELNNKCLTPQRERSGSESSVDQKTVA 1529
Query: 180 QTTITSHFAKGPAKR---KPQ-EESERAKSDESIKEEDKDQDEKRRR--------VTSRE 227
+T + G ++ KP ER++SD S + K + R+R V S+
Sbjct: 1530 RTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKS 1589
Query: 228 RVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQ 287
R++ P R++SG+ E +++ + P PK R +R+G
Sbjct: 1590 RLS-------PRRSRSGSSPE-VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSS 1641
Query: 288 A---DEDEDGDEKDEKKHRSQPKDLAAKR----RPEEKEPEKVNPQISDEKDEDEKEEKR 340
+ +G E PK A+R PE K + P+ + E K
Sbjct: 1642 SKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKA 1701
Query: 341 R 341
R
Sbjct: 1702 R 1702
Score = 48.5 bits (114), Expect = 5e-05
Identities = 55/259 (21%), Positives = 98/259 (37%), Gaps = 27/259 (10%)
Query: 123 ADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQ--VTGIRAEPSPSPRITRKSTRQ 180
+ A+SP PRTP R G + RD + S+ ++G PR + +
Sbjct: 1420 SSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSE 1479
Query: 181 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEP-- 238
+ K PQ R++S S + +K +R R S V + A P
Sbjct: 1480 CD-----SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLG 1534
Query: 239 ERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKD 298
+R++SG+ E + + ++R S + P K K + + +R+G + D
Sbjct: 1535 QRSRSGSSQELDVKPSASPQERSESDS-SPDSKAKTRTPLRQRSRSGSSPEVD------- 1586
Query: 299 EKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDED-EKEEKRRKTTPKEPTEKKMARAK 357
K R P+ + PE K+ + P+ D E + + P+ ++ +
Sbjct: 1587 -SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645
Query: 358 --------TVMNSKTHPPK 368
+ +S HPPK
Sbjct: 1646 GPSPEGSSSTESSPEHPPK 1664
Score = 48.1 bits (113), Expect = 7e-05
Identities = 77/375 (20%), Positives = 141/375 (37%), Gaps = 58/375 (15%)
Query: 28 LKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLN 87
L+++ + E++ ++EK+ L + N ET ++ ++E LA++ N
Sbjct: 73 LEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKN 132
Query: 88 KDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEA 147
+ L G + V+G + + EA++ A PPKP S R S+S
Sbjct: 133 ERLRAAFGIS--DSYVDGSSFDPQRRAREAKQ----PAPEPPKPYSLVRESSSSRSPTPK 186
Query: 148 KRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDE 207
++ + + G R+E S SPR RK + +K R E +R
Sbjct: 187 QKKK----KKKKDRGRRSESS-SPRRERKKS---------SKKKKHRSESESKKRKHRSP 232
Query: 208 SIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQT-- 265
+ K + K +D+KR+R S + A A S + ++ R + +
Sbjct: 233 TPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALA 292
Query: 266 -KEPTPKQKLKEE------------------PDREARAGVQADEDEDGDEKDEKKHRSQP 306
+ P+P + E P+ + ED+D D+K++ R P
Sbjct: 293 GRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSP 352
Query: 307 KDLAAKRRPEEKEPEKV-------NPQ------ISDE--KDEDEKEEKRRKTTPKEPTEK 351
+ PE P + +PQ +S E E R ++ PK P +
Sbjct: 353 SPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP--E 410
Query: 352 KMARAKTVMNSKTHP 366
K+ ++ + +S P
Sbjct: 411 KLPQSSSSESSPPSP 425
Score = 45.4 bits (106), Expect = 4e-04
Identities = 53/241 (21%), Positives = 84/241 (34%), Gaps = 42/241 (17%)
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSP 171
+++ + R+ + +P + T S S + RSR A+A T A SPSP
Sbjct: 239 KSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSP 298
Query: 172 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVAR 231
R+ + G + E A S EDKD+D+K + T R
Sbjct: 299 ASGRRGEGDAPFSE---PGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT------R 349
Query: 232 PLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEE----PDREARAGVQ 287
P P+ PER+ +G + P P L E P A +
Sbjct: 350 PSPS--PERSSTGP--------------------EPPAPTPLLAERHGGSPQPLATTPLS 387
Query: 288 ADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKE 347
+ E + RS PK EK P+ + + S + K + ++P+
Sbjct: 388 QEPVNPPSEASPTRDRSPPKS-------PEKLPQSSSSESSPPSPQPTKVSRHASSSPES 440
Query: 348 P 348
P
Sbjct: 441 P 441
Score = 45.1 bits (105), Expect = 6e-04
Identities = 58/279 (20%), Positives = 103/279 (36%), Gaps = 33/279 (11%)
Query: 108 ENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAK--RSRDPPASASQVTGIRA 165
E ++R+ RR + S P+ K R RRS+S + RSR PP +
Sbjct: 1677 EPKTKSRTPPRR---RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP 1733
Query: 166 EPSPSPRITRK----STRQTTITSHFAKGPA----------------KRKPQEESERAKS 205
EP+ R +R+ S+ +T TS + P+ K + +R+ S
Sbjct: 1734 EPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793
Query: 206 DESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEK-----EEKR 260
+S + + R RVT R R + P R +S +RT R KR
Sbjct: 1794 SQSTSRR-RQRSRSRSRVTRRRRGGSGYHSRSPARQES-SRTSSRRRRGRSRTPPTSRKR 1851
Query: 261 LRSQTK-EPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKE 319
RS+T P + + + P R+ + + S+ + + +
Sbjct: 1852 SRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRS 1911
Query: 320 PEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKT 358
+ +P RR++ + PT ++ +R++T
Sbjct: 1912 RSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRT 1950
Score = 43.1 bits (100), Expect = 0.002
Identities = 59/266 (22%), Positives = 104/266 (39%), Gaps = 33/266 (12%)
Query: 111 NQARSEARRVGMADANSPPKPLSKPRTP-RRSKSDGEAKRSRDPPASASQVTGIRAEPSP 169
+++R+ ARR + + +P + S+ RTP RR +S RSR P S+ S
Sbjct: 584 SRSRTPARR--RSRSRTPTRRRSRSRTPARRGRS-----RSRTPARRRSRTRSPVRRRSR 636
Query: 170 SPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERV 229
S R+S R + T PA+R A+ S + + RR SR R
Sbjct: 637 SRSPARRSGRSRSRT------PARRGRSRSRTPARRGRS-----RSRTPARRSGRSRSRT 685
Query: 230 ARPLPAEEPERAKSGTRTEKE-EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQA 288
PA R +S +RT + R +R RS ++ P + + +R+ ++
Sbjct: 686 ----PA---RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ 738
Query: 289 DEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQIS------DEKDEDEKEEKRRK 342
+ KK R + + P K +++ + S K + + +R +
Sbjct: 739 RRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSR 798
Query: 343 TTPKEPTEKKMARAKTVMNSKTHPPK 368
+ +P K + +S + PPK
Sbjct: 799 SGSSQPKAKSRTPPRRSRSSSSPPPK 824
Score = 41.2 bits (95), Expect = 0.008
Identities = 42/197 (21%), Positives = 80/197 (40%), Gaps = 22/197 (11%)
Query: 193 KRKPQEESERAKSDESIKEEDKDQDEKRRRVTS-----RERVARPLPAEE-PERAKSGTR 246
+RK + E + +E ++E+ ++ + + +V + E+ P EE P + + T
Sbjct: 61 ERKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTE 120
Query: 247 TEKEEERDEKEEKRLRS-----------QTKEPTPKQKLKEEPDREARAGVQADEDEDGD 295
T + E +EK+ +RLR+ + +P + + ++P E +
Sbjct: 121 THQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSS 180
Query: 296 EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEK----DEDEKEEKRRKTTPKEPTEK 351
K + + K RR E P + + S +K + + K+ K R TPK +
Sbjct: 181 RSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKS 240
Query: 352 KMARAKTVMNSKTHPPK 368
K + K S T PK
Sbjct: 241 KDKKRKR-SRSTTPAPK 256
Score = 40.0 bits (92), Expect = 0.018
Identities = 37/190 (19%), Positives = 69/190 (36%), Gaps = 17/190 (8%)
Query: 104 NGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGI 163
+GR G+ SE +SP +P +P K + ++S P+ + + +
Sbjct: 300 SGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSST 359
Query: 164 RAE-PSPSPRITRK------STRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQ 216
E P+P+P + + T ++ P++ P + KS E + + +
Sbjct: 360 GPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSE 419
Query: 217 D--------EKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEP 268
+ R +S +P PA R S + T K R KR +S + P
Sbjct: 420 SSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSK--NRSHGRAKRDKSHSHTP 477
Query: 269 TPKQKLKEEP 278
+ + P
Sbjct: 478 SRRMGRSRSP 487
Score = 40.0 bits (92), Expect = 0.018
Identities = 48/261 (18%), Positives = 96/261 (36%), Gaps = 25/261 (9%)
Query: 133 SKPRTP--RRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTT------IT 184
S+ R+P RRS+S RSR P + R S S R+ ++
Sbjct: 506 SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSR 565
Query: 185 SHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLP-AEEPERAKS 243
S +G ++ + R++S + + + RRR SR R + P R +S
Sbjct: 566 SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS 625
Query: 244 GTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEE---PDREARAGVQADEDEDGDEKDE- 299
TR+ + R +++ TP ++ + P R R+ + G +
Sbjct: 626 RTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRT 685
Query: 300 ------------KKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKE 347
++ RS+ + L + R + P++ S + +++ +R++
Sbjct: 686 PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNS 745
Query: 348 PTEKKMARAKTVMNSKTHPPK 368
E K +R + + P+
Sbjct: 746 SPEMKKSRISSRRSRSLSSPR 766
Score = 40.0 bits (92), Expect = 0.018
Identities = 44/213 (20%), Positives = 80/213 (37%), Gaps = 20/213 (9%)
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSP 171
++RS A V + S P+++ R+ R+ + RSR PP + R S +P
Sbjct: 1910 RSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTR------RRSRSRTP 1963
Query: 172 RITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVAR 231
+TR+ +R T + ++ P R +S + + R +R R
Sbjct: 1964 PVTRRRSRSRTSPITRRRSRSRTSP---VTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRS 2020
Query: 232 PLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTP-----KQKLKEEPD---REAR 283
P R++S T + + +R +++ TP K+ L P R +
Sbjct: 2021 RTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSA 2080
Query: 284 AGVQADEDEDGDEKDEKKH---RSQPKDLAAKR 313
+G +D + H R+ P L + R
Sbjct: 2081 SGSSSDRSRSATPPATRNHSGSRTPPVALNSSR 2113
Score = 37.0 bits (84), Expect = 0.16
Identities = 32/182 (17%), Positives = 63/182 (34%), Gaps = 15/182 (8%)
Query: 136 RTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRK 195
R P + + EA R PP EP+P+ R R S+ ++ +S + +
Sbjct: 2578 RVPSPTPAPKEAVREGRPP-----------EPTPAKRKRRSSSSSSSSSSSSSSSSSSSS 2626
Query: 196 PQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEP---ERAKSGTRTEKEEE 252
S + S S + + + +P ++P ER R +
Sbjct: 2627 SSSSSSSSSSSSSSSSSSSSSSPSPAK-PGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685
Query: 253 RDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAK 312
RD + + + P+P+ +++ + G + + D K+ R P +
Sbjct: 2686 RDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR 2745
Query: 313 RR 314
R
Sbjct: 2746 HR 2747
Score = 35.0 bits (79), Expect = 0.60
Identities = 42/169 (24%), Positives = 60/169 (35%), Gaps = 33/169 (19%)
Query: 130 KPLSKPRTP-RRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKS---TRQTTITS 185
+P +K RTP RRS+S S PP S+ ++ S SP KS RQ +ITS
Sbjct: 803 QPKAKSRTPPRRSRSS-----SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857
Query: 186 HFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGT 245
PQ + E E + R SR + P R KS T
Sbjct: 858 ----------PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS----GSSPPRVKSST 903
Query: 246 RTEKEEERDEKEE----------KRLRSQTKEPTPKQKLKEEPDREARA 284
+ R + +R S + P+P + R +R+
Sbjct: 904 PPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
Score = 35.0 bits (79), Expect = 0.60
Identities = 37/178 (20%), Positives = 67/178 (37%), Gaps = 25/178 (14%)
Query: 106 RLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRA 165
R+ + A EA R G PP+P R R S S + S +S+S
Sbjct: 2578 RVPSPTPAPKEAVREGR-----PPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSS------ 2626
Query: 166 EPSPSPRITRKSTRQTTITSHFAKGPAK------------RKPQEESERAKSDESIKEED 213
S S + S+ ++ +S + PAK +KP R++S +
Sbjct: 2627 -SSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685
Query: 214 KDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPK 271
+D R R + P P+ +++ S R + +R + + + + P+P+
Sbjct: 2686 RDSRSLSYSPVERRRPS-PQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPR 2742
Score = 32.0 bits (71), Expect = 5.0
Identities = 41/185 (22%), Positives = 71/185 (38%), Gaps = 14/185 (7%)
Query: 95 GAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPP 154
G Y+ R E+ S RR G + +PP + R+ R S + + RSR P
Sbjct: 1816 GGSGYHSRSPARQESSRT--SSRRRRGRS--RTPPTSRKRSRS-RTSPAPWKRSRSRASP 1870
Query: 155 ASASQ-------VTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDE 207
A+ + ++ R+ SP R+S +T++T ++ A + S R+++
Sbjct: 1871 ATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS-RSRTPP 1929
Query: 208 SIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKE 267
+ + + RR SR R R TR +R RS+T
Sbjct: 1930 VTRRRSRSRTPTTRR-RSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSP 1988
Query: 268 PTPKQ 272
T ++
Sbjct: 1989 VTRRR 1993
Score = 31.2 bits (69), Expect = 8.6
Identities = 57/251 (22%), Positives = 91/251 (36%), Gaps = 44/251 (17%)
Query: 69 RKEELSEEGYLAKVKSLLNKDLS------LENGAHAYNREVNGRLENGNQARSEARRVGM 122
R LS AK + L + LS + R +G + ++R+ RR
Sbjct: 758 RSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRR--- 814
Query: 123 ADANSPPKPLSKPRTPRR----SKSDGEAKRSRDPP---------ASASQVTGIRA---E 166
+ ++S P P K +TP R S S +S PP A+ VT R E
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFE 874
Query: 167 PSPSPRI-TRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESI---------KEEDKDQ 216
SP P + +R +R + S + + P++ R+ S + +
Sbjct: 875 SSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSS 934
Query: 217 DEKRRRVTSR-----ERVARPLPAEE----PERAKSGTRTEKEEERDEKEEKRLRSQTKE 267
RVTSR R P E P + SG+ + + + E ++ S +
Sbjct: 935 SPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSIS 994
Query: 268 PTPKQKLKEEP 278
P PK K + P
Sbjct: 995 PYPKVKAQTPP 1005
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 64.3 bits (155), Expect = 9e-10
Identities = 70/329 (21%), Positives = 124/329 (37%), Gaps = 38/329 (11%)
Query: 63 DLETKLRKEELSEEGYLAKV-KSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVG 121
D KL +E+ +E ++ K ++ E RE E + E R
Sbjct: 286 DTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERER 345
Query: 122 MADANSPPKPLSKPRTPRRSKS-DGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQ 180
D + + RT R + D E R RD S+ + R KS +
Sbjct: 346 ERDRD-------RDRTKERDRDRDRERDRDRDRERSSDR-------NKDRSRSREKSRDR 391
Query: 181 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 240
+ +R+ + E ER + E +E ++++D+KR R E E R
Sbjct: 392 EREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLR 451
Query: 241 AKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKD-- 298
K E+ + + +E K+ R KE +++ + E +EA+ + ED D D D
Sbjct: 452 EKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPK 511
Query: 299 -------EKKHRSQPKDLAAKRRPEEKEPEKV-------------NPQISDEKDEDEKEE 338
+K+ R + K++ A R ++E E++ +P ++ E E E
Sbjct: 512 YYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAER 571
Query: 339 KRRKTTPKEPTEKKMARAKTVMNSKTHPP 367
+R+ +EP ++ K K P
Sbjct: 572 RRQPQIKQEPESEEEEEEKQEKEEKREEP 600
Score = 58.5 bits (140), Expect = 5e-08
Identities = 71/342 (20%), Positives = 142/342 (41%), Gaps = 32/342 (9%)
Query: 38 EKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSL---LNKDLSLEN 94
E E L LLH+ LQ K L ++ K K +L E + AK K+ + +
Sbjct: 136 EPESTLRALRLLHD-LQIGEKKLLVKVDAKT-KAQLDE--WKAKKKASNGNARPETVTND 191
Query: 95 GAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPL-SKPRTPRRSKSDGEAKRSRDP 153
A + E R + A R ++ N+P + S PR ++ K + +R
Sbjct: 192 DEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVA 251
Query: 154 PA------SASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDE 207
P + + I E I+R+ ++ + K+ +E+ ++ K +
Sbjct: 252 PLIPYPLITKEDINAIEMEEDKRDLISREISK--------FRDTHKKLEEEKGKKEKERQ 303
Query: 208 SIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDE-----KEEKRLR 262
I++E ++++ +R R RER R E + E+E ERD KE R R
Sbjct: 304 EIEKERRERERERER--ERERREREREREREREREKEKERERERERDRDRDRTKERDRDR 361
Query: 263 SQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEK 322
+ ++ ++ + +++ + D + + + E++ + + + R E+E E+
Sbjct: 362 DRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERER 421
Query: 323 VNPQISDEK---DEDEKEEKRRKTTPKEPTEKKMARAKTVMN 361
+ D+K +EDE++ R+ ++ EK+ A + + N
Sbjct: 422 EREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKN 463
Score = 49.3 bits (116), Expect = 3e-05
Identities = 43/180 (23%), Positives = 83/180 (46%), Gaps = 24/180 (13%)
Query: 195 KPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER-----------AKS 243
K E ER K+ E KE +++++ +R +R+ L + +R K
Sbjct: 462 KNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKR 521
Query: 244 GTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHR 303
EKE E DE++ KR + + +E + + PD +A E + E + R
Sbjct: 522 LRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDA---------ELQRMEQEAERR 572
Query: 304 SQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTP-KEPTEKKMARAKTVMNS 362
QP+ K+ PE +E E+ + ++++E +EE+ + P +PT + ++ A +V ++
Sbjct: 573 RQPQ---IKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSA 629
Score = 44.3 bits (103), Expect = 0.001
Identities = 75/369 (20%), Positives = 130/369 (35%), Gaps = 66/369 (17%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKS 84
R R ++ ER+ E+E +EK E + LE KLR++E + + +
Sbjct: 407 REREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQ------ER 460
Query: 85 LLNKDLSLENGAHAYNREVNGRLENGNQARSEARRV-----GMADANSPPK-----PLSK 134
L N ++ Y +E E + EA+R+ D PK L K
Sbjct: 461 LKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQK 520
Query: 135 PRTPRRSKSDGEAK-RSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAK 193
R + + + + R R+ + AE P P + Q A+
Sbjct: 521 RLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQE----------AE 570
Query: 194 RKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEER 253
R+ Q + ++ E +EE ++++EKR E EEPE+ K R
Sbjct: 571 RRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEE--------EEPEQKP----CLKPTLR 618
Query: 254 DEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHR---------- 303
+ S + TP P E+ G+ + D++ ++HR
Sbjct: 619 PISSAPSVSSASGNATP-----NTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLG 673
Query: 304 -----SQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEK-------EEKRRKTTPKEPTEK 351
QP + K+ P + K + SD+ K E+ + T TE+
Sbjct: 674 ASNSPGQPNSVKRKKLPVDSVFNKFEDEDSDDVPRKRKLVPLDYGEDDKNATKGTVNTEE 733
Query: 352 KMARAKTVM 360
K K+++
Sbjct: 734 KRKHIKSLI 742
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 64.3 bits (155), Expect = 9e-10
Identities = 67/321 (20%), Positives = 126/321 (39%), Gaps = 35/321 (10%)
Query: 45 KLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVN 104
KL + H+F++ I+ ETK+ E+ E L + L + E A +E
Sbjct: 445 KLKVQHKFVEEIIE------ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE-- 496
Query: 105 GRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIR 164
EA +A SP K + P + +GE + + G +
Sbjct: 497 --------EEPEAEEEEVAAKKSPVKATA----PEVKEEEGEKEEEEGQEEEEEEDEGAK 544
Query: 165 AEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVT 224
++ + ++ + + K +++ E A+ +E+ +E+K +EK V
Sbjct: 545 SDQAEEGGSEKEGSSE--------KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA 596
Query: 225 SRERVARPLPAEEPERAKSGTRTEKEEERDEK--EEKRLRSQTKEPTPKQKLKEEPDREA 282
++E + E+PE+AKS EE+ + + + + K P PK ++E+
Sbjct: 597 TKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 656
Query: 283 RAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK 342
++ +E G K + + P E+ K ++K+E+EKE K +
Sbjct: 657 ---PKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK--E 711
Query: 343 TTPKEPTEKKMARAKTVMNSK 363
+E EKK + K V K
Sbjct: 712 APKEEKVEKKEEKPKDVPEKK 732
Score = 60.5 bits (145), Expect = 1e-08
Identities = 44/180 (24%), Positives = 83/180 (46%), Gaps = 6/180 (3%)
Query: 194 RKPQEESERAKSD----ESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK 249
+KP+ E+ + K E I EE K +DEK + + L E K ++
Sbjct: 437 QKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE 496
Query: 250 EEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED-GDEKDEKKHRSQPKD 308
EE E+EE + + T + +EE ++E G + +E+ED G + D+ + K+
Sbjct: 497 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 556
Query: 309 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPT-EKKMARAKTVMNSKTHPP 367
++++ E+E + + E+ E ++E+K + + + T E+ +A AK K P
Sbjct: 557 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP 616
Score = 59.7 bits (143), Expect = 2e-08
Identities = 78/346 (22%), Positives = 145/346 (41%), Gaps = 42/346 (12%)
Query: 23 DVRRRL--KDLERDSLT-EKECVKEKLNLLHEFLQTEI---KNQLCDLETKLRKEELSEE 76
+ RR+L K +E +S+ KE ++ +L+ + E ++ ++ + LE +LR +
Sbjct: 319 EYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMA 378
Query: 77 GYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPR 136
+L + + LLN ++L+ AY + + G E R A + + P +P
Sbjct: 379 RHLREYQDLLNVKMALDIEIAAYRKLLEG---------EETRFSTFAGSITGPLYTHRPP 429
Query: 137 TPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKP 196
SK + V I E + T IT A + K
Sbjct: 430 ITISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKK 489
Query: 197 QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE-RAKSGTRTEKE-EERD 254
+ E+ + E+ +EE V +++ P+ A PE + + G + E+E +E +
Sbjct: 490 EAAEEKEEEPEAEEEE----------VAAKK---SPVKATAPEVKEEEGEKEEEEGQEEE 536
Query: 255 EKEEKRLRSQTKEPTPKQK----LKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLA 310
E+E++ +S E +K KEE ++E E E+ + K+EKK + +++A
Sbjct: 537 EEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA 596
Query: 311 AKRR----PEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 352
K + ++PEK + + EEK + PK P E+K
Sbjct: 597 TKEELVADAKVEKPEKAKSPV----PKSPVEEKGKSPVPKSPVEEK 638
Score = 49.7 bits (117), Expect = 2e-05
Identities = 67/330 (20%), Positives = 128/330 (38%), Gaps = 24/330 (7%)
Query: 17 AISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEE 76
A+S+ ++ + ++ E + E+E V K + + + E+K + + E + +EE EE
Sbjct: 481 AVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV-KATAPEVKEEEGEKEEEEGQEEEEEE 539
Query: 77 GYLAKVKSLLNKDLSLENGAH---AYNREVNGRLENGNQARSEARRVGMADANSPPKPLS 133
AK D + E G+ + +E + E +A +E + +
Sbjct: 540 DEGAK------SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSE 593
Query: 134 KPRTPRRSKSDGEAKR---SRDP-PASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAK 189
+ T +D + ++ ++ P P S + G P KS + K
Sbjct: 594 EVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 653
Query: 190 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK 249
P + P EE ++ +S EE + V + A E+ E + +
Sbjct: 654 SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP 713
Query: 250 EEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDL 309
+EE+ EK+E++ + P++K E P +E +A + K K H +
Sbjct: 714 KEEKVEKKEEK-----PKDVPEKKKAESPVKE-----EAVAEVVTITKSVKVHLEKETKE 763
Query: 310 AAKRRPEEKEPEKVNPQISDEKDEDEKEEK 339
K +EKE EK + E++ +K K
Sbjct: 764 EGKPLQQEKEKEKAGGEGGSEEEGSDKGAK 793
Score = 45.8 bits (107), Expect = 3e-04
Identities = 68/341 (19%), Positives = 121/341 (35%), Gaps = 53/341 (15%)
Query: 72 ELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKP 131
E EG A+ K + E A + ++E +A+S + + + P P
Sbjct: 572 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 631
Query: 132 LSK---------PRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTT 182
S P++P K +S S V+ E + + +
Sbjct: 632 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 691
Query: 183 ITSHFAKGPAKRKPQEESERAKSDESIK---EEDKDQDEKRRRVT--SRERVA------- 230
+ KG K + ++E + A +E ++ E+ KD EK++ + E VA
Sbjct: 692 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 751
Query: 231 --------------RPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKE 276
+PL +E E+ K+G EEE +K K R + + + KE
Sbjct: 752 SVKVHLEKETKEEGKPLQ-QEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKE 810
Query: 277 EPDREARAGVQADEDEDG--------DEKDEKKHRSQPKDLAAKRRPEEKEPEK----VN 324
E ++E + E+E G DEKK + ++ + EK +
Sbjct: 811 EVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGAT 870
Query: 325 PQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTH 365
I+ +K E+ +T E+K+ K V +H
Sbjct: 871 KYITKSVTVTQKVEEHEET-----FEEKLVSTKKVEKVTSH 906
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 64.3 bits (155), Expect = 9e-10
Identities = 67/321 (20%), Positives = 126/321 (39%), Gaps = 35/321 (10%)
Query: 45 KLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVN 104
KL + H+F++ I+ ETK+ E+ E L + L + E A +E
Sbjct: 69 KLKVQHKFVEEIIE------ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE-- 120
Query: 105 GRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIR 164
EA +A SP K + P + +GE + + G +
Sbjct: 121 --------EEPEAEEEEVAAKKSPVKATA----PEVKEEEGEKEEEEGQEEEEEEDEGAK 168
Query: 165 AEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVT 224
++ + ++ + + K +++ E A+ +E+ +E+K +EK V
Sbjct: 169 SDQAEEGGSEKEGSSE--------KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVA 220
Query: 225 SRERVARPLPAEEPERAKSGTRTEKEEERDEK--EEKRLRSQTKEPTPKQKLKEEPDREA 282
++E + E+PE+AKS EE+ + + + + K P PK ++E+
Sbjct: 221 TKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPV 280
Query: 283 RAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK 342
++ +E G K + + P E+ K ++K+E+EKE K +
Sbjct: 281 ---PKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVK--E 335
Query: 343 TTPKEPTEKKMARAKTVMNSK 363
+E EKK + K V K
Sbjct: 336 APKEEKVEKKEEKPKDVPEKK 356
Score = 60.5 bits (145), Expect = 1e-08
Identities = 44/180 (24%), Positives = 83/180 (46%), Gaps = 6/180 (3%)
Query: 194 RKPQEESERAKSD----ESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK 249
+KP+ E+ + K E I EE K +DEK + + L E K ++
Sbjct: 61 QKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE 120
Query: 250 EEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDED-GDEKDEKKHRSQPKD 308
EE E+EE + + T + +EE ++E G + +E+ED G + D+ + K+
Sbjct: 121 EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKE 180
Query: 309 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPT-EKKMARAKTVMNSKTHPP 367
++++ E+E + + E+ E ++E+K + + + T E+ +A AK K P
Sbjct: 181 GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP 240
Score = 49.7 bits (117), Expect = 2e-05
Identities = 67/330 (20%), Positives = 128/330 (38%), Gaps = 24/330 (7%)
Query: 17 AISLPDDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEE 76
A+S+ ++ + ++ E + E+E V K + + + E+K + + E + +EE EE
Sbjct: 105 AVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV-KATAPEVKEEEGEKEEEEGQEEEEEE 163
Query: 77 GYLAKVKSLLNKDLSLENGAH---AYNREVNGRLENGNQARSEARRVGMADANSPPKPLS 133
AK D + E G+ + +E + E +A +E + +
Sbjct: 164 DEGAK------SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSE 217
Query: 134 KPRTPRRSKSDGEAKR---SRDP-PASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAK 189
+ T +D + ++ ++ P P S + G P KS + K
Sbjct: 218 EVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 277
Query: 190 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK 249
P + P EE ++ +S EE + V + A E+ E + +
Sbjct: 278 SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP 337
Query: 250 EEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDL 309
+EE+ EK+E++ + P++K E P +E +A + K K H +
Sbjct: 338 KEEKVEKKEEK-----PKDVPEKKKAESPVKE-----EAVAEVVTITKSVKVHLEKETKE 387
Query: 310 AAKRRPEEKEPEKVNPQISDEKDEDEKEEK 339
K +EKE EK + E++ +K K
Sbjct: 388 EGKPLQQEKEKEKAGGEGGSEEEGSDKGAK 417
Score = 45.8 bits (107), Expect = 3e-04
Identities = 68/341 (19%), Positives = 121/341 (35%), Gaps = 53/341 (15%)
Query: 72 ELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKP 131
E EG A+ K + E A + ++E +A+S + + + P P
Sbjct: 196 EAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP 255
Query: 132 LSK---------PRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTT 182
S P++P K +S S V+ E + + +
Sbjct: 256 KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAK 315
Query: 183 ITSHFAKGPAKRKPQEESERAKSDESIK---EEDKDQDEKRRRVT--SRERVA------- 230
+ KG K + ++E + A +E ++ E+ KD EK++ + E VA
Sbjct: 316 SKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 375
Query: 231 --------------RPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKE 276
+PL +E E+ K+G EEE +K K R + + + KE
Sbjct: 376 SVKVHLEKETKEEGKPLQ-QEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKE 434
Query: 277 EPDREARAGVQADEDEDG--------DEKDEKKHRSQPKDLAAKRRPEEKEPEK----VN 324
E ++E + E+E G DEKK + ++ + EK +
Sbjct: 435 EVEQETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGAT 494
Query: 325 PQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTH 365
I+ +K E+ +T E+K+ K V +H
Sbjct: 495 KYITKSVTVTQKVEEHEET-----FEEKLVSTKKVEKVTSH 530
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 64.3 bits (155), Expect = 9e-10
Identities = 51/193 (26%), Positives = 96/193 (49%), Gaps = 7/193 (3%)
Query: 128 PPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVT-GIRAEPSP--SPRITRKSTRQTTIT 184
PP+ S P TP+ E++ P S ++ + PS SP +Q + T
Sbjct: 250 PPQIKSLPATPQGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSST 309
Query: 185 SHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSR-ERVARPLPAEEPERAKS 243
S F R+ ++ + ++++ +DQ+ +++ R ER + EE +RAK
Sbjct: 310 SPFPTSTPLRRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKE 369
Query: 244 GTRTEKEEERDEKEEKRLRSQTK---EPTPKQKLKEEPDREARAGVQADEDEDGDEKDEK 300
+ +KEEE++ KE++R + K E KQ+LKEE +E + ++A +E +++EK
Sbjct: 370 EAKKKKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEK 429
Query: 301 KHRSQPKDLAAKR 313
+ R + K + A++
Sbjct: 430 RLREEEKRIKAEK 442
Score = 51.2 bits (121), Expect = 8e-06
Identities = 68/293 (23%), Positives = 115/293 (39%), Gaps = 25/293 (8%)
Query: 127 SPPKPLSKPRT-PRR-----SKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQ 180
S P+ S PR PR+ S++ G + + P + +R S T +
Sbjct: 206 SCPELTSGPRMCPRKEQDSWSEAGGILFKGKVPMVVLQDILAVRPPQIKSLPATPQGKNM 265
Query: 181 TTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPER 240
T + P + S + + E K+ TS + PL +
Sbjct: 266 TPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKF 325
Query: 241 AKSGTRTEKEEERDEKEEKRLRSQTK---EPTPKQKLKEEPDR---EARAGVQADEDEDG 294
K T EK + R +++++RL Q K E K+KLKEE R EA+ + +++
Sbjct: 326 VKGST--EKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKE 383
Query: 295 DEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPK--EPTEKK 352
E+ EK+ + + + +R EE+ E+ E E + EEKR+K K EK+
Sbjct: 384 KERREKREKDEKEKAEKQRLKEERRKER------QEALEAKLEEKRKKEEEKRLREEEKR 437
Query: 353 MARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIF 405
+ K + PK Q + L G+ P + E +L + + F
Sbjct: 438 IKAEKAEITRFFQKPKTPQAPKTLAG---SCGKFAPFEIKEHMVLAPRRRTAF 487
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 64.3 bits (155), Expect = 9e-10
Identities = 63/275 (22%), Positives = 109/275 (39%), Gaps = 36/275 (13%)
Query: 101 REVNGRLENGNQARSEAR------RVGMADANSPPKPLSKPRTPRRSKSDGEAKRS---- 150
RE + R E N++R+E+R R+G + P P R R S+ D + S
Sbjct: 535 REESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHD 594
Query: 151 ----------------RDPPASASQVTGIRAEPSPSPRITR-KSTRQTTITSHFAKGPAK 193
RD A + R R R + R ++ H +
Sbjct: 595 SWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDEL 654
Query: 194 RKPQEESERA------KSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRT 247
+ + ER + DE +E D++++ R R RER E ER R
Sbjct: 655 ERDERREERRVDRVDDRRDERARERDRERERDRERERERERERD--REREKERELERERA 712
Query: 248 EKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPK 307
+ E EKE R R + ++ +++ + E DRE + +E E E++ ++ R + +
Sbjct: 713 REREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERER 772
Query: 308 DLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK 342
+ + R +KE E+ +K D++ EKR +
Sbjct: 773 E-RERARERDKERERQRDWEDKDKGRDDRREKREE 806
Score = 63.2 bits (152), Expect = 2e-09
Identities = 69/332 (20%), Positives = 134/332 (40%), Gaps = 14/332 (4%)
Query: 32 ERDSLTEKECVKEKLNLLHEFLQTEIKNQLC-DLETKLRKEELSEEGYLAKVKSLLNKDL 90
+ D+ E+ + +L E +TEI+N+ + +++R + + +V L K
Sbjct: 518 KEDTYPEESRSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGRSR--GRVPELPEKGS 575
Query: 91 SLENGAHAYNREVNGRLENGNQARS---EARRVGMADANSPPKPLSKPRTPRRSKSDGEA 147
G+ + N + + RS E R D + S R R + D
Sbjct: 576 RGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSFER--RHGERDRRD 633
Query: 148 KRSRDP-PASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSD 206
R RD P+S + G E R R+ R + + R+ E ER +
Sbjct: 634 NRERDQRPSSPIRHQGRNDELERDER--REERRVDRVDDR--RDERARERDRERERDRER 689
Query: 207 ESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTK 266
E +E ++D++ ++ R RER E ER + R + E+E +R R + +
Sbjct: 690 ERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKER 749
Query: 267 EPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEP-EKVNP 325
E +++ +E R + E E E+D+++ R + + K R + +E E++
Sbjct: 750 EREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRE 809
Query: 326 QISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357
+ DE++ K+R P+ ++ + +
Sbjct: 810 DRNPRDGHDERKSKKRYRNEGSPSPRQSPKRR 841
Score = 60.8 bits (146), Expect = 1e-08
Identities = 86/368 (23%), Positives = 149/368 (40%), Gaps = 51/368 (13%)
Query: 33 RDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSL 92
R+ L E+ E N ++EI+N ++ R EL E+G S ++ S
Sbjct: 531 RNHLREESSRTEIRNESRNESRSEIRNDRMG-RSRGRVPELPEKGSRGSRGSQIDSHSSN 589
Query: 93 ENGAHAYN-------REVNGRLENGNQARSEA--RRVGMADANSPPKPLSKPRTPRR--S 141
N ++ R+ +N +QAR + RR G D + +P +P R
Sbjct: 590 SNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQG 649
Query: 142 KSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQE-ES 200
++D + R +V R E + R+ R+ + + K +E E
Sbjct: 650 RNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELER 709
Query: 201 ERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERD------ 254
ERA+ E +E+++D++ R R RER E ER + R + EER+
Sbjct: 710 ERAREREREREKERDRERDRDRDHDRER------ERERERDREKEREREREERERERERE 763
Query: 255 -------EKEEKRLRSQTKEPTPKQKLKEEPD------REARAGVQAD---EDEDGDEKD 298
E+E +R R + KE +Q+ E+ D RE R ++ D D + K
Sbjct: 764 RERERERERERERARERDKE-RERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKS 822
Query: 299 EKKHRSQ--PKDLAAKRRPEEKEPEKVNPQISDEKDEDE-------KEEKRRKTTPKEPT 349
+K++R++ P + +R E P+ D+K+E + ++ R +P T
Sbjct: 823 KKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLT 882
Query: 350 EKKMARAK 357
E + R K
Sbjct: 883 EDRQGRWK 890
Score = 49.7 bits (117), Expect = 2e-05
Identities = 72/337 (21%), Positives = 128/337 (37%), Gaps = 31/337 (9%)
Query: 22 DDVRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAK 81
D R R ++ ERD E+E +E+ E + + + + E +++ E +
Sbjct: 732 DHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERE-----R 786
Query: 82 VKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRS 141
+ +KD ++ RE N E + P P P+ R
Sbjct: 787 QRDWEDKDKGRDDRRE--KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREH 844
Query: 142 KSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQ-EES 200
D +A S D ++ P S + S T RKP+ +ES
Sbjct: 845 SPDSDAYNSGDDKNEKHRLLSQVVRPQESRSL---SPSHLTEDRQGRWKEEDRKPERKES 901
Query: 201 ERAKSDESIKEEDKDQDEKRRRV----TSRERVARPLPAEEPERAKSGTRTEKEEERDEK 256
R ++ +KE+ D++R + +SR R + + E ++ R E ++ K
Sbjct: 902 SRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAK 961
Query: 257 EEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE 316
+K+ P +K KE+ R ++ EDG KK Q K K+R +
Sbjct: 962 IQKK---------PIKKKKEDDVGIERGNIETTS-EDGQVFSPKK--GQKKKSIEKKRKK 1009
Query: 317 EKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKM 353
K + ISDE+ + ++KR TP T++++
Sbjct: 1010 SKG----DSDISDEEAAQQSKKKRGPRTPPITTKEEL 1042
Score = 40.0 bits (92), Expect = 0.018
Identities = 43/211 (20%), Positives = 87/211 (41%), Gaps = 21/211 (9%)
Query: 131 PLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKG 190
PL + +P S S +R + PP S + R + + T SH +
Sbjct: 366 PLRRSASPYPSHSLSSPQRKQSPPRHRSPM-----------REKGRHDHERTSQSHDRRH 414
Query: 191 PAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKE 250
+ + + +R K +E ++DQ R RE P + +R + ++
Sbjct: 415 ERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDRE------PRDGRDRRDARDTRDRR 468
Query: 251 EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKD-EKKHRSQPKDL 309
E RD ++ + R + ++ + K +P R++R+ A + D + +D +K + P++
Sbjct: 469 ELRDSRDMRDSR-EMRDYSRDTKESRDP-RDSRSTRDAHDYRDREGRDTHRKEDTYPEES 526
Query: 310 AAKRRPEEKEPEKVNPQISDEKDEDEKEEKR 340
+ R +E E +I +E + + E R
Sbjct: 527 RSYGRNHLRE-ESSRTEIRNESRNESRSEIR 556
Score = 36.2 bits (82), Expect = 0.27
Identities = 40/174 (22%), Positives = 65/174 (37%), Gaps = 24/174 (13%)
Query: 184 TSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKS 243
T F GP+ R S +S E + +++ + +R+ E R +S
Sbjct: 56 TCRFVHGPSPRGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKR-------NTEES 108
Query: 244 GTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHR 303
+ KE R EK TKE TP E + D+ ++GD + H
Sbjct: 109 SSPVRKESSRGRHREKEDIKITKERTP-----ESEEENVEWETNRDDSDNGDINYDYVHE 163
Query: 304 SQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357
L KR+ ++E K+ E E EKR + K+ ++ R+K
Sbjct: 164 ---LSLEMKRQKIQRELMKL---------EQENMEKREEIIIKKEVSPEVVRSK 205
Score = 35.8 bits (81), Expect = 0.35
Identities = 64/348 (18%), Positives = 130/348 (37%), Gaps = 34/348 (9%)
Query: 24 VRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVK 83
++R L LE++++ ++E + K + E +++++ LRK S + +
Sbjct: 173 IQRELMKLEQENMEKREEIIIKKEVSPEVVRSKLSPS-----PSLRKSSKSPKRKSSPKS 227
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENG--NQARSEARRVGMADANSPPKPLSKPRTPRRS 141
S +K + A + + + N NQ++ + R SPP P+ P
Sbjct: 228 SSASKK---DRKTSAVSSPLLDQQRNSKTNQSKKKGPRTP-----SPPPPI--PEDIALG 277
Query: 142 KSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESE 201
K E + +D ++ R R R R T+ + R S
Sbjct: 278 KKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSR---HHSS 334
Query: 202 RAKSDESIKEEDKDQDEKRRRVTSRERV--------ARPLPAEE---PERAKSGTR--TE 248
++S SI+ KR S +R A P P+ P+R +S R +
Sbjct: 335 SSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSP 394
Query: 249 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKD 308
E+ E+ +S + ++ + + DRE + + + ++D + + +P+D
Sbjct: 395 MREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRD 454
Query: 309 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKT-TPKEPTEKKMAR 355
+R + + D +D E + R T ++P + + R
Sbjct: 455 GRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTR 502
Score = 34.7 bits (78), Expect = 0.78
Identities = 54/266 (20%), Positives = 92/266 (34%), Gaps = 53/266 (19%)
Query: 94 NGAHAYNREVNGR---LENGNQARSEARRVGMA-DANSPPKPLSKPRTPRRSKSDGEAKR 149
+ AH + +GR L +G++ R + + + + + S L + R + SD + R
Sbjct: 1212 DSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSR 1271
Query: 150 S----RDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKS 205
S R P S QV R+ + + + E ER +
Sbjct: 1272 SHSSRRSSPESDRQVHSRSGSFDSRDRLQERD---------------RYEHDRERERERR 1316
Query: 206 DESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQT 265
D +E D+D D+ R R+R+ +E ER+ + +KR
Sbjct: 1317 DTRQREWDRDADKDWPRNRDRDRL-------------------RERERERERDKR----- 1352
Query: 266 KEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNP 325
+ L E +R V+ D D D D E K AK E + +
Sbjct: 1353 ------RDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTS 1406
Query: 326 QISDEKDEDEKEEKRRKTTPKEPTEK 351
+ S D++ ++ E T K
Sbjct: 1407 RDSLALDKERMDKDLGSVQGFEETNK 1432
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 63.9 bits (154), Expect = 1e-09
Identities = 57/209 (27%), Positives = 101/209 (48%), Gaps = 22/209 (10%)
Query: 165 AEPSPSPRITRKSTRQT---TITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRR 221
A+P PS + ++S +T T +H K P + +E K D+ IK E K ++
Sbjct: 549 AKPLPSKSVRKESKEETPEVTKVNHVEKPP--KVESKEKVMVKKDKPIKTETKPSVTEKE 606
Query: 222 RVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDRE 281
V S+E + P+ AE E+ + + + +E+ K+E +++ P K++ KE+P +E
Sbjct: 607 -VPSKEEPS-PVKAEVAEKQATDVKPKAAKEKTVKKETKVK-----PEDKKEEKEKPKKE 659
Query: 282 ARAGVQADEDEDGDEKDEKKHRSQPKDLAAK--RRPEEKEPEKV----NPQISDEKDEDE 335
V ED+ +K+EK + + K K ++ E+KEP+K P +K+ +
Sbjct: 660 ----VAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKK 715
Query: 336 KEEKRRKTTPKEPTEKKMARAKTVMNSKT 364
+E+K K KEP ++ K S T
Sbjct: 716 EEKKEVKKEEKEPKKEIKKLPKDAKKSST 744
Score = 62.4 bits (150), Expect = 3e-09
Identities = 64/293 (21%), Positives = 124/293 (42%), Gaps = 40/293 (13%)
Query: 65 ETKLRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMAD 124
+TKL++ S E K L +K + E+ +E + E++ M
Sbjct: 532 QTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEK--PPKVESKEKVMVK 589
Query: 125 ANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTIT 184
+ P K +KP S ++ E +P ++V +A K+ ++ T
Sbjct: 590 KDKPIKTETKP-----SVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKV 644
Query: 185 SHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSG 244
K K KP++E + + IK+E+K + E+ ++ +E
Sbjct: 645 KPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKE----------------- 687
Query: 245 TRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRS 304
+KEE+++ K+E K+ TP +++K+E +E + V+ +E E +K+ +
Sbjct: 688 --IKKEEKKEPKKE------VKKETPPKEVKKEVKKEEKKEVKKEEKE-----PKKEIKK 734
Query: 305 QPKDLAAKRRP--EEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMAR 355
PKD P E K+P + P++ +K+E K++ PKE + K+ +
Sbjct: 735 LPKDAKKSSTPLSEAKKPAALKPKV-PKKEESVKKDSVAAGKPKEKGKIKVIK 786
Score = 55.8 bits (133), Expect = 3e-07
Identities = 57/256 (22%), Positives = 112/256 (43%), Gaps = 34/256 (13%)
Query: 123 ADANSPPKPLSKPRTPRRSKSDGEAKRSR--------DPPASASQVTGIRAEPSPSPRIT 174
AD+ KP +KP + + + + + PP S+ + + P T
Sbjct: 539 ADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTET 598
Query: 175 RKSTRQTTITSHFAKGPAKRKPQEESE-----RAKSDESIKEEDK--DQDEKRRRVTSRE 227
+ S + + S P K + E+ +A ++++K+E K +D+K + ++
Sbjct: 599 KPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKK 658
Query: 228 RVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQ 287
VA+ E+ K + +KEE + E +++ + + KEP + K KE P +E + V+
Sbjct: 659 EVAKK---EDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVK-KETPPKEVKKEVK 714
Query: 288 ADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKE 347
+E +K+ KK +PK K+ P K+ +K + +S+ K K PK
Sbjct: 715 KEE-----KKEVKKEEKEPKK-EIKKLP--KDAKKSSTPLSEAK-------KPAALKPKV 759
Query: 348 PTEKKMARAKTVMNSK 363
P +++ + +V K
Sbjct: 760 PKKEESVKKDSVAAGK 775
Score = 53.5 bits (127), Expect = 2e-06
Identities = 44/166 (26%), Positives = 78/166 (46%), Gaps = 11/166 (6%)
Query: 195 KPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERD 254
K + +RA S ES+K K K R S+E E+ + E +E+
Sbjct: 531 KQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPEVTKVNHVEKP---PKVESKEKVM 587
Query: 255 EKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQAD-EDEDGDEKDEKKHRSQPKDLAAKR 313
K++K ++++TK P KE P +E + V+A+ ++ + K + + K
Sbjct: 588 VKKDKPIKTETK---PSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKV 644
Query: 314 RPEEKEPEKVNPQISDEKDED----EKEEKRRKTTPKEPTEKKMAR 355
+PE+K+ EK P+ K ED +KEEK +K K+ +K++ +
Sbjct: 645 KPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKK 690
Score = 49.7 bits (117), Expect = 2e-05
Identities = 81/400 (20%), Positives = 155/400 (38%), Gaps = 59/400 (14%)
Query: 21 PDDVRRRLKDLERDSLTEKEC---VKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEG 77
P+D ++ K+ + + +KE +K++ E ++ E+K ++ E K K+E+ +E
Sbjct: 646 PED-KKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704
Query: 78 YLAKVKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRT 137
+VK + K+ E +E + + +A++ + + KP+
Sbjct: 705 PPKEVKKEVKKEEKKE-----VKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKV 759
Query: 138 PRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAK------GP 191
P++ +S + + P ++ I+ E + + T + A GP
Sbjct: 760 PKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGP 819
Query: 192 AKRKPQEES------ERAKSDESIKEEDKD------------QDEKRRRVTS-------- 225
AK E S + K E +K E+ D +DE++ + T
Sbjct: 820 AKELEAERSLMSSPEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQ 879
Query: 226 RERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPK--------QKLKEE 277
+ER PAE P+ + T E E E+ +E + + Q + K ++ E
Sbjct: 880 KEREVTKGPAESPDEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSET 939
Query: 278 PDREARAGVQADE--DEDGDEK---DEKKHRSQPKDLAAKRRPE----EKEPEKVNPQIS 328
D E +A + E +EDG+E KH + +AK + EK +
Sbjct: 940 GDYEEKAETEEAEEPEEDGEEHVCVSASKHSPTEDEESAKAEADAYIREKRESVASGDDR 999
Query: 329 DEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPK 368
E+D DE EK +E +++ +A+ + P K
Sbjct: 1000 AEEDMDEAIEKGEAEQSEEEADEE-DKAEDAREEEYEPEK 1038
Score = 32.7 bits (73), Expect = 3.0
Identities = 38/212 (17%), Positives = 75/212 (35%), Gaps = 7/212 (3%)
Query: 198 EESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKE 257
E+ E +S+E EEDK +D + + A ++A E++
Sbjct: 1009 EKGEAEQSEEEADEEDKAEDAREEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTP 1068
Query: 258 EKRLRSQTKEPTPKQKLKEE--PDREARAGVQADEDEDGDEKDE----KKHRSQPKDLAA 311
K+L +Q+ P + +E P +DE+ D+ +E + ++++
Sbjct: 1069 TKQLGAQSPGREPASSIHDETLPGGSESEATASDEENREDQPEEFTATSGYTQSTIEISS 1128
Query: 312 KRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQ 371
+ P + E +SDE + +E E ++ E + + + P
Sbjct: 1129 EPTPMD-EMSTPRDVMSDETNNEETESPSQEFVNITKYESSLYSQEYSKPADVTPLNGFS 1187
Query: 372 CGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLS 403
G D D K + P + +K S
Sbjct: 1188 EGSKTDATDGKDYNASASTISPPSSMEEDKFS 1219
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 63.5 bits (153), Expect = 2e-09
Identities = 54/235 (22%), Positives = 105/235 (44%), Gaps = 26/235 (11%)
Query: 130 KPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAK 189
+P K R S+S ++R R P +S + + R+ R+ + + + +K
Sbjct: 238 EPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRS---------RRRSHSKSRSRRRSK 288
Query: 190 GPAKRKP--QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRT 247
P +R+ +E R++S +++ K+ EK+R T P R++S +R
Sbjct: 289 SPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTP------PKSYSTARRSRSASR- 341
Query: 248 EKEEERDEKEEKRLRSQTKEPTPKQKLKEEPD-REARAGVQADEDEDGDEKDEKKHRSQP 306
E R + RS K +PK+KL P R + + D+D++ + ++ S+
Sbjct: 342 ---ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKK 398
Query: 307 KDLAAKRRPEEK--EPEKVNPQISDEKDEDEK--EEKRRKTTPKEPTEKKMARAK 357
K K + E+ E +K Q++ + DE+E+ + ++ K K+P E + K
Sbjct: 399 KKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTK 453
Score = 55.1 bits (131), Expect = 6e-07
Identities = 63/266 (23%), Positives = 107/266 (40%), Gaps = 31/266 (11%)
Query: 100 NREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTP---RRSKSDGEAKRSRDPPAS 156
++E+ ++ +A+S D + S+ R+ RR+ S +RSR
Sbjct: 216 SKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRR 275
Query: 157 ASQVTGIRAEPSPSPRITRKSTRQTTITSHF-AKGPAKRKPQEESERAKSDE---SIKEE 212
S S SPR R +R+ S +K K+K +E +R+K+ S
Sbjct: 276 RSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR 335
Query: 213 DKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRT------------EKEEERDEKE--- 257
+ +RRR SR P P+R S + + +KE RDE+E
Sbjct: 336 SRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERST 395
Query: 258 EKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPE- 316
K+ +S+ KE ++K + + D + +E++ D + EKK +P + + + E
Sbjct: 396 SKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEKKPIETGSPKTKEC 455
Query: 317 --EK------EPEKVNPQISDEKDED 334
EK KVN E+D D
Sbjct: 456 SVEKGTGDSLRESKVNGDDHHEEDMD 481
Score = 36.2 bits (82), Expect = 0.27
Identities = 38/186 (20%), Positives = 75/186 (40%), Gaps = 29/186 (15%)
Query: 192 AKRKPQEESERAKSDESIKE---EDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE 248
+ ++ +E +R + +S+ E ++EKRR SR R R +S +R+
Sbjct: 215 SSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSR 274
Query: 249 KEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKD 308
+ + R R ++K P ++ E R +R+ + D ++D++K RS
Sbjct: 275 RRSH----SKSRSRRRSKSPRRRRSHSRERGRRSRS---TSKTRDKKKEDKEKKRS---- 323
Query: 309 LAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRK----TTPKEP--TEKKMARAKTVMNS 362
K P K + + +RR +PK+P ++K++R+ +
Sbjct: 324 ---------KTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRH 374
Query: 363 KTHPPK 368
K K
Sbjct: 375 KKEKKK 380
Score = 32.3 bits (72), Expect = 3.9
Identities = 25/124 (20%), Positives = 49/124 (39%), Gaps = 8/124 (6%)
Query: 266 KEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNP 325
K T ++++E R A + D+K+EK+ S+ + + +RR + +
Sbjct: 211 KSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSR 270
Query: 326 QISDEKDEDEKEEKRRKTTPKEPTEKKMARA-KTVMNSKTHPPKCIQCGQYLDDPDLKYG 384
S + + +RR +P+ R ++ SKT K +D + K
Sbjct: 271 SRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKK-------KEDKEKKRS 323
Query: 385 QHPP 388
+ PP
Sbjct: 324 KTPP 327
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 62.8 bits (151), Expect = 3e-09
Identities = 64/276 (23%), Positives = 113/276 (40%), Gaps = 25/276 (9%)
Query: 127 SPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQ---VT---------GIRAEPSPSPRIT 174
SPPK K R R + + E PAS + VT G R +PS +
Sbjct: 290 SPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRS 349
Query: 175 RKSTRQTTITSHFAKGP--AKRKPQEESER-AKSDESIKEEDKDQDEKRRRVTSRERVAR 231
R R++ H+ + A+R ER K D+S E K+ RV R+
Sbjct: 350 RDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDH 409
Query: 232 PLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADED 291
+E P R + K+ + + KE R+ K+ K K+K+ ++R+ ++ E
Sbjct: 410 RNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRS--KSKEK 467
Query: 292 EDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDED-EKEEKRRKTTPKEPTE 350
E+D K +R++ K + ++ + + E K + SD K +D E+ + K+ E
Sbjct: 468 SKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKS 527
Query: 351 KKMARAKTVMNSKTHPPKCIQCGQYLDDPDLKYGQH 386
+ +K+ + + +C D+ G+H
Sbjct: 528 NEHDHSKSKEKDRRAQSRSREC-------DITKGKH 556
Score = 57.4 bits (137), Expect = 1e-07
Identities = 76/363 (20%), Positives = 140/363 (38%), Gaps = 33/363 (9%)
Query: 25 RRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELS---EEGYLAK 81
+R+ K + +KE K K + ++E +N ++ +R EE+ E +L +
Sbjct: 229 KRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMR 288
Query: 82 VKSLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLS--KPRTPR 139
+ +N RE N +Q S RR+ + + K + RTP
Sbjct: 289 KSPPKADEKERKNRERERERECN---PPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPS 345
Query: 140 RSKSDGEAKRSRDPPASASQVTGI-RAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQE 198
RS+S +RS PP ++ R S R + + + P + K ++
Sbjct: 346 RSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERK 405
Query: 199 --------ESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKE 250
ES K+++ K +D + K R + + +RAKS +R++ +
Sbjct: 406 ITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSK 465
Query: 251 E-----ERDEK----EEKRLRSQTK-------EPTPKQKLKEEPDREARAGVQADEDEDG 294
E ERD K EEKR+RS++K + KQ + D+E + + +
Sbjct: 466 EKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 295 DEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMA 354
+ +S+ KD A+ R E + K + E + R + ++ +
Sbjct: 526 KSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRS 585
Query: 355 RAK 357
R+K
Sbjct: 586 RSK 588
Score = 52.4 bits (124), Expect = 4e-06
Identities = 54/286 (18%), Positives = 117/286 (40%), Gaps = 33/286 (11%)
Query: 24 VRRRLKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVK 83
+R R K + +++ EKE + E +++ K++ LE+K + + S+ +
Sbjct: 485 MRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSK--QLESKSNEHDHSKSKEKDRRA 542
Query: 84 SLLNKDLSLENGAHAYNREVNGRLENGNQARSEARRVGMADANSPPKPLSKPRTPRRSKS 143
+++ + G H+Y N R +++R +RRV + RT R +S
Sbjct: 543 QSRSRECDITKGKHSY----NSRTRERSRSRDRSRRV-------------RSRTHDRDRS 585
Query: 144 -DGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESER 202
E R R+ + R +P R K R+ +R+ SER
Sbjct: 586 RSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRR------------RRRDSRSSER 633
Query: 203 AKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLR 262
+S K++ ++Q+ K + + ++ + S EK+ +RD+ +++
Sbjct: 634 EESQSRNKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIK 693
Query: 263 SQTKEPTPKQK-LKEEPDREARAGVQADEDEDGDEKDEKKHRSQPK 307
+++ K LK + D + R+ V+ + + ++++ H K
Sbjct: 694 QSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDHVHEKNKK 739
Score = 48.1 bits (113), Expect = 7e-05
Identities = 64/340 (18%), Positives = 136/340 (40%), Gaps = 42/340 (12%)
Query: 36 LTEKECVKEKLNLLHEFLQTEIKNQLCDLETKLRKEELSEEGYLAKVKSLLNKDLSLENG 95
+T+ V E N +E + ++ E +R+ ++ Y KVK ++
Sbjct: 406 ITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSK 465
Query: 96 AHAYNREVNGRLENGNQARSEARRVGMADANSPPKPL---SKPRTPRRSKSDGEAK---- 148
+ ++E + + + R +R G N K SK + RS+S ++K
Sbjct: 466 EKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 149 RSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTIT----SHFAKGPAKRKPQEESERAK 204
+S + S S+ RA+ +R+ IT S+ ++ + + ++ S R +
Sbjct: 526 KSNEHDHSKSKEKDRRAQ---------SRSRECDITKGKHSYNSRTRERSRSRDRSRRVR 576
Query: 205 SDESIKEEDKDQD-------EKRRRVTSRERVARPLPA-----EEPERAKSGTRTEKEEE 252
S ++ + ++ E RRR SR R R P + R + +E+EE
Sbjct: 577 SRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREES 636
Query: 253 RDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAK 312
+ ++K ++K K+ + E +++ D + + +++K R Q K
Sbjct: 637 QSRNKDKYRNQESKSSHRKENSESEKRMYSKS---RDHNSSNNSREKKADRDQSPFSKIK 693
Query: 313 RRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKK 352
+ ++ E + +++++EK R + KE + K
Sbjct: 694 QSSQDNE-------LKSSMLKNKEDEKIRSSVEKENQKSK 726
Score = 43.9 bits (102), Expect = 0.001
Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 2/132 (1%)
Query: 191 PAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKE 250
P + +EE +R KS S D D +S + EE ++K + ++
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEE--KSKKRKKKHRK 236
Query: 251 EERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLA 310
R K+EK+ R ++K+ + E + + ++ V+ +E E +S PK
Sbjct: 237 NSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADE 296
Query: 311 AKRRPEEKEPEK 322
+R+ E+E E+
Sbjct: 297 KERKNRERERER 308
Score = 43.5 bits (101), Expect = 0.002
Identities = 61/335 (18%), Positives = 122/335 (36%), Gaps = 33/335 (9%)
Query: 56 EIKNQLCDLETK----LRKEELSEEGYLAKVKSLLNKDLSLENGAHAYNREVNGRLENGN 111
EI+NQ D +K +R E +KVK K + + + + + + ++ +
Sbjct: 153 EIENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQS 212
Query: 112 QARSEARRVGMADANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSP 171
+ S + + K + + + K + K+S+ +S S+ + A+P +
Sbjct: 213 SSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQST- 271
Query: 172 RITRKSTRQTTITSHF--AKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERV 229
R + F K P K +E R + E Q +R R
Sbjct: 272 --VRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRS 329
Query: 230 ARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAG---V 286
R + P R ++ +R+ + R R P +Q+++ +G +
Sbjct: 330 GRKIKGRGPRRYRTPSRSRSRD--------RFRRSETPPHWRQEMQRAQRMRVSSGERWI 381
Query: 287 QADEDEDGDEKDEKK------------HRSQPKDLAAKRRPEEK-EPEKVNPQISDEKDE 333
+ D+ E + K+ ++ HR+ + K E+K + K N + D +
Sbjct: 382 KGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRN 441
Query: 334 DEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPK 368
EK++K + K K +++K SK K
Sbjct: 442 SEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSK 476
Score = 37.7 bits (86), Expect = 0.092
Identities = 41/240 (17%), Positives = 90/240 (37%), Gaps = 20/240 (8%)
Query: 130 KPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAK 189
K SK R RR+ + +++ + S+ E S S K R
Sbjct: 430 KSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRN--------- 480
Query: 190 GPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEK 249
+ K + + E++KE++K D K + +ER +++ E + K
Sbjct: 481 ---EEKRMRSRSKGRDHENVKEKEKQSDSKGK---DQERSRSKEKSKQLESKSNEHDHSK 534
Query: 250 EEERDEKEEKRLR----SQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQ 305
+E+D + + R R ++ K + + R+ V++ + + ++ HR +
Sbjct: 535 SKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYR 594
Query: 306 PKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTH 365
++ + R +E + P S KD + R + +E + + + + +H
Sbjct: 595 EQEYRRRGRSRSRE-RRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSH 653
Score = 34.3 bits (77), Expect = 1.0
Identities = 24/127 (18%), Positives = 54/127 (42%), Gaps = 3/127 (2%)
Query: 221 RRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR 280
R + +++ A P E G K + + KEEK+ R ++ + +
Sbjct: 152 REIENQKTDAASKPFAEVRILSCGELIPKSKVK--KEEKK-RHKSSSSSSSSSSDSDSSS 208
Query: 281 EARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKR 340
++++ + + E E+ KK + + + + K + E+K+ +K S E + + E +
Sbjct: 209 DSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQP 268
Query: 341 RKTTPKE 347
+ T E
Sbjct: 269 QSTVRPE 275
Score = 33.1 bits (74), Expect = 2.3
Identities = 31/138 (22%), Positives = 59/138 (42%), Gaps = 12/138 (8%)
Query: 267 EPTPKQKLK-EEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNP 325
E PK K+K EE R + + D D + + S D + + K+ +K +
Sbjct: 176 ELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHR 235
Query: 326 QISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLDDPDLKY-- 383
+ S + +KE+K+RK + K + + A N + P ++ + P+ ++
Sbjct: 236 KNSRKH---KKEKKKRKKSKKSASSESEAE-----NLEAQPQSTVRPEEIPPIPENRFLM 287
Query: 384 GQHPPDAVDEPQMLTNEK 401
+ PP A DE + E+
Sbjct: 288 RKSPPKA-DEKERKNRER 304
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 62.4 bits (150), Expect = 3e-09
Identities = 63/240 (26%), Positives = 103/240 (42%), Gaps = 19/240 (7%)
Query: 126 NSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITS 185
NSP +P + TP + K +SR P + G + S I ST+ I
Sbjct: 1135 NSPLEPDTS--TPLKKKKGWPKGKSRKP-IHWKKRPGRKPGFKLSREIMPVSTQACVIEP 1191
Query: 186 HFAKGPAKRKPQ----EESERAKSDESIKEEDKDQDEKRRRVTSRER------VARPLPA 235
+ A RKP+ EE+ K D + EE K+++E + E + +PA
Sbjct: 1192 IVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPA 1251
Query: 236 EEPERAKSGTRTEKEEERDEKEEKRLR---SQTKEPTPKQKLKE-EPDREARAGVQADED 291
P + + TE +E E+EE++ R Q + +Q+L+E EP+ E A + ++
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 292 EDGDEKDEKK-HRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 350
+D D DE H K + +P +E K P + + + ++ R K KE TE
Sbjct: 1312 DDHDADDEDDGHLESTKKKELEEQP-TREDVKEEPGVQESFLDANMQKSREKIKDKEETE 1370
Score = 49.3 bits (116), Expect = 3e-05
Identities = 51/201 (25%), Positives = 90/201 (44%), Gaps = 26/201 (12%)
Query: 242 KSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKK 301
K+G + + +E + E K P P+++ KEE + +A A +A+E E+ D +
Sbjct: 1197 KAGRKPKIQESEETVEPKE-----DMPLPEER-KEEEEMQAEA-EEAEEGEEEDAASSEV 1249
Query: 302 HRSQPKDLAAKRRPEEKEP----EKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357
+ P D + E KEP E+ P++S+E + + EE++++ EP E++ A A+
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPRVSEE--QRQSEEEQQELEEPEPEEEEDAAAE 1307
Query: 358 TVMNSKTHPPKCIQCGQYLDDPDLKYGQHPP---DAVDEPQM--------LTNEKLSIFD 406
T N H G +L+ K + P D +EP + + + I D
Sbjct: 1308 TAQND-DHDADDEDDG-HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKD 1365
Query: 407 ANESGFESYEALPQHKLTCFS 427
E+ +S E P H + S
Sbjct: 1366 KEETELDSEEEQPSHDTSVVS 1386
Score = 38.5 bits (88), Expect = 0.054
Identities = 35/192 (18%), Positives = 70/192 (36%), Gaps = 25/192 (13%)
Query: 129 PKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFA 188
P P + EA+ + A++S+V A P+ S T++ +
Sbjct: 1218 PLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPA--ASPADSSNSPETETKEPEVEEEEE 1275
Query: 189 KGPAKRK---------------PQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPL 233
K + P+EE + A + D D ++ +++++
Sbjct: 1276 KPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQ 1335
Query: 234 PAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR------EARAGVQ 287
P E + + G + + +K ++++ KE T +E+P E AG +
Sbjct: 1336 PTREDVKEEPGVQESFLDANMQKSREKIKD--KEETELDSEEEQPSHDTSVVSEQMAGSE 1393
Query: 288 ADEDEDGDEKDE 299
D +ED K+E
Sbjct: 1394 DDHEEDSHTKEE 1405
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 62.4 bits (150), Expect = 3e-09
Identities = 63/240 (26%), Positives = 103/240 (42%), Gaps = 19/240 (7%)
Query: 126 NSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITS 185
NSP +P + TP + K +SR P + G + S I ST+ I
Sbjct: 1135 NSPLEPDTS--TPLKKKKGWPKGKSRKP-IHWKKRPGRKPGFKLSREIMPVSTQACVIEP 1191
Query: 186 HFAKGPAKRKPQ----EESERAKSDESIKEEDKDQDEKRRRVTSRER------VARPLPA 235
+ A RKP+ EE+ K D + EE K+++E + E + +PA
Sbjct: 1192 IVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPA 1251
Query: 236 EEPERAKSGTRTEKEEERDEKEEKRLR---SQTKEPTPKQKLKE-EPDREARAGVQADED 291
P + + TE +E E+EE++ R Q + +Q+L+E EP+ E A + ++
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 292 EDGDEKDEKK-HRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 350
+D D DE H K + +P +E K P + + + ++ R K KE TE
Sbjct: 1312 DDHDADDEDDGHLESTKKKELEEQP-TREDVKEEPGVQESFLDANMQKSREKIKDKEETE 1370
Score = 49.3 bits (116), Expect = 3e-05
Identities = 51/201 (25%), Positives = 90/201 (44%), Gaps = 26/201 (12%)
Query: 242 KSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKK 301
K+G + + +E + E K P P+++ KEE + +A A +A+E E+ D +
Sbjct: 1197 KAGRKPKIQESEETVEPKE-----DMPLPEER-KEEEEMQAEA-EEAEEGEEEDAASSEV 1249
Query: 302 HRSQPKDLAAKRRPEEKEP----EKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357
+ P D + E KEP E+ P++S+E + + EE++++ EP E++ A A+
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPRVSEE--QRQSEEEQQELEEPEPEEEEDAAAE 1307
Query: 358 TVMNSKTHPPKCIQCGQYLDDPDLKYGQHPP---DAVDEPQM--------LTNEKLSIFD 406
T N H G +L+ K + P D +EP + + + I D
Sbjct: 1308 TAQND-DHDADDEDDG-HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKD 1365
Query: 407 ANESGFESYEALPQHKLTCFS 427
E+ +S E P H + S
Sbjct: 1366 KEETELDSEEEQPSHDTSVVS 1386
Score = 38.5 bits (88), Expect = 0.054
Identities = 35/192 (18%), Positives = 70/192 (36%), Gaps = 25/192 (13%)
Query: 129 PKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFA 188
P P + EA+ + A++S+V A P+ S T++ +
Sbjct: 1218 PLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPA--ASPADSSNSPETETKEPEVEEEEE 1275
Query: 189 KGPAKRK---------------PQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPL 233
K + P+EE + A + D D ++ +++++
Sbjct: 1276 KPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQ 1335
Query: 234 PAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR------EARAGVQ 287
P E + + G + + +K ++++ KE T +E+P E AG +
Sbjct: 1336 PTREDVKEEPGVQESFLDANMQKSREKIKD--KEETELDSEEEQPSHDTSVVSEQMAGSE 1393
Query: 288 ADEDEDGDEKDE 299
D +ED K+E
Sbjct: 1394 DDHEEDSHTKEE 1405
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 62.4 bits (150), Expect = 3e-09
Identities = 63/240 (26%), Positives = 103/240 (42%), Gaps = 19/240 (7%)
Query: 126 NSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITS 185
NSP +P + TP + K +SR P + G + S I ST+ I
Sbjct: 1135 NSPLEPDTS--TPLKKKKGWPKGKSRKP-IHWKKRPGRKPGFKLSREIMPVSTQACVIEP 1191
Query: 186 HFAKGPAKRKPQ----EESERAKSDESIKEEDKDQDEKRRRVTSRER------VARPLPA 235
+ A RKP+ EE+ K D + EE K+++E + E + +PA
Sbjct: 1192 IVSIPKAGRKPKIQESEETVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPA 1251
Query: 236 EEPERAKSGTRTEKEEERDEKEEKRLR---SQTKEPTPKQKLKE-EPDREARAGVQADED 291
P + + TE +E E+EE++ R Q + +Q+L+E EP+ E A + ++
Sbjct: 1252 ASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQN 1311
Query: 292 EDGDEKDEKK-HRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 350
+D D DE H K + +P +E K P + + + ++ R K KE TE
Sbjct: 1312 DDHDADDEDDGHLESTKKKELEEQP-TREDVKEEPGVQESFLDANMQKSREKIKDKEETE 1370
Score = 49.3 bits (116), Expect = 3e-05
Identities = 51/201 (25%), Positives = 90/201 (44%), Gaps = 26/201 (12%)
Query: 242 KSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKK 301
K+G + + +E + E K P P+++ KEE + +A A +A+E E+ D +
Sbjct: 1197 KAGRKPKIQESEETVEPKE-----DMPLPEER-KEEEEMQAEA-EEAEEGEEEDAASSEV 1249
Query: 302 HRSQPKDLAAKRRPEEKEP----EKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAK 357
+ P D + E KEP E+ P++S+E + + EE++++ EP E++ A A+
Sbjct: 1250 PAASPADSSNSPETETKEPEVEEEEEKPRVSEE--QRQSEEEQQELEEPEPEEEEDAAAE 1307
Query: 358 TVMNSKTHPPKCIQCGQYLDDPDLKYGQHPP---DAVDEPQM--------LTNEKLSIFD 406
T N H G +L+ K + P D +EP + + + I D
Sbjct: 1308 TAQND-DHDADDEDDG-HLESTKKKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKD 1365
Query: 407 ANESGFESYEALPQHKLTCFS 427
E+ +S E P H + S
Sbjct: 1366 KEETELDSEEEQPSHDTSVVS 1386
Score = 38.5 bits (88), Expect = 0.054
Identities = 35/192 (18%), Positives = 70/192 (36%), Gaps = 25/192 (13%)
Query: 129 PKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFA 188
P P + EA+ + A++S+V A P+ S T++ +
Sbjct: 1218 PLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPA--ASPADSSNSPETETKEPEVEEEEE 1275
Query: 189 KGPAKRK---------------PQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPL 233
K + P+EE + A + D D ++ +++++
Sbjct: 1276 KPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQ 1335
Query: 234 PAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDR------EARAGVQ 287
P E + + G + + +K ++++ KE T +E+P E AG +
Sbjct: 1336 PTREDVKEEPGVQESFLDANMQKSREKIKD--KEETELDSEEEQPSHDTSVVSEQMAGSE 1393
Query: 288 ADEDEDGDEKDE 299
D +ED K+E
Sbjct: 1394 DDHEEDSHTKEE 1405
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 62.4 bits (150), Expect = 3e-09
Identities = 56/212 (26%), Positives = 96/212 (45%), Gaps = 12/212 (5%)
Query: 153 PPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEE 212
PP V G P P P S +Q K +R+ E S + +EE
Sbjct: 418 PPPDRQAVPG---RPGPFP-----SKQQVADEDEIWK-QRRRQQSEISAAVERARKRREE 468
Query: 213 DKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQ 272
++ + E++R+ E++ R L + K + E E EKE +R + KE ++
Sbjct: 469 EERRMEEQRKAACAEKLKR-LDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQER 527
Query: 273 KLKEEPDREARAGVQAD-EDEDGDEKDEKKHRSQPKDLAAKRRPE-EKEPEKVNPQISDE 330
+ + E DRE + + + E E +++ +K R Q K+ +R+ E EKE +K+ Q +
Sbjct: 528 EKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKEC 587
Query: 331 KDEDEKEEKRRKTTPKEPTEKKMARAKTVMNS 362
+ E E+E+ K P+EP + M + NS
Sbjct: 588 ELEKEREKLEEKIEPREPNLEPMVEKQESENS 619
Score = 57.0 bits (136), Expect = 1e-07
Identities = 61/252 (24%), Positives = 114/252 (45%), Gaps = 36/252 (14%)
Query: 125 ANSPPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPS--PRITRKSTRQTT 182
+NSP + S+ + + S+++ E K+ D ++ + I A+PS + P S Q
Sbjct: 342 SNSPKENNSEDQGSKASENN-ENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQER 400
Query: 183 ITSHFAKGPAKRKPQEESERAK-----------SDESIKEEDKDQDEKRRR------VTS 225
TS P K Q+ + S + + +ED+ ++RR+
Sbjct: 401 GTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVE 460
Query: 226 RERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQ--KLKEEPDREAR 283
R R R EE ER R E+ ++ +++L K+P+P++ + + E +RE
Sbjct: 461 RARKRR----EEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERERE 516
Query: 284 AGVQADEDEDGD---EKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKR 340
++ +++++ + EKD ++ + + K+L EKE EK + K E EKE +R
Sbjct: 517 KELEKEQEQEREKEREKDRERQQEKEKEL-------EKEQEKQREMEKERKQEKEKELER 569
Query: 341 RKTTPKEPTEKK 352
+K KE + K
Sbjct: 570 QKEKEKELQKMK 581
Score = 45.8 bits (107), Expect = 3e-04
Identities = 38/175 (21%), Positives = 72/175 (41%), Gaps = 14/175 (8%)
Query: 166 EPSPSPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTS 225
E PSP R+ R+ +R+ ++E E+ + E KE +KD++ ++ +
Sbjct: 496 EKQPSPEEIREREREK-----------EREREKELEKEQEQEREKEREKDRERQQEKEKE 544
Query: 226 RERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAG 285
E+ E ER + EKE ER +++EK L+ ++ + KE E +
Sbjct: 545 LEKEQEKQREMEKERKQE---KEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIE 601
Query: 286 VQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKR 340
+ E EK E ++ ++ R + EK + E + + + R
Sbjct: 602 PREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPR 656
Score = 43.9 bits (102), Expect = 0.001
Identities = 43/172 (25%), Positives = 82/172 (47%), Gaps = 27/172 (15%)
Query: 196 PQE--ESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEER 253
P+E E ER K E KE +K+Q+++R + ++R + +E E+ E+E++R
Sbjct: 501 PEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEK-------EQEKQR 553
Query: 254 D-EKE-----EKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQP- 306
+ EKE EK L Q ++ QK+KE+ + + +++ ++ +EK +P
Sbjct: 554 EMEKERKQEKEKELERQKEKEKELQKMKEQEK-------ECELEKEREKLEEKIEPREPN 606
Query: 307 -KDLAAKRRPE---EKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMA 354
+ + K+ E KE E V + + E E +T P+ ++ + A
Sbjct: 607 LEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPA 658
Score = 40.8 bits (94), Expect = 0.011
Identities = 42/212 (19%), Positives = 90/212 (42%), Gaps = 26/212 (12%)
Query: 163 IRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKPQE-ESERAKSDESIKEEDKDQDEKRR 221
+ +PSP R+ ++ K + + +E E +R + E KE +K+Q EK+R
Sbjct: 495 LEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ-EKQR 553
Query: 222 RVTSRERVARPLPAEEPERAKSGTRTEKEEERD---EKEEKRL------RSQTKEPTPKQ 272
+ + + E + + + KE+E++ EKE ++L R EP ++
Sbjct: 554 EMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK 613
Query: 273 KLKEEPDREARAGVQADEDEDGDEKD--------EKKHRSQPKDLAAK---RRPEEKEPE 321
+ E + V +D + EK+ E + SQP+ ++ ++ P
Sbjct: 614 QESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPP 673
Query: 322 KVNPQISDEKDEDEKEEKRR----KTTPKEPT 349
+ Q K + ++++++ +T P +P+
Sbjct: 674 RFQRQQEQMKQQQWQQQQQQGVLPQTVPSQPS 705
Score = 33.1 bits (74), Expect = 2.3
Identities = 45/257 (17%), Positives = 96/257 (37%), Gaps = 20/257 (7%)
Query: 127 SPPKPLSKPR---TPRRSKSD----GEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTR 179
S P P ++P+ TP+ ++ EA ++ +A V + E P R+S+
Sbjct: 809 SDPYPHAEPQQATTPKATEEPEDVRSEAALDQEQITAAYSVEHNQLEAHPKADFIRESS- 867
Query: 180 QTTITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPE 239
+ + ++ +P +++S E DQ R P+ +
Sbjct: 868 EAQVQKFLSRSVEDVRPHHTDA---NNQSACFEAPDQKTLSAPQEERISAVESQPSRKRS 924
Query: 240 RAKSGTRTEKEEERDEKEEKRLRSQTKE----PTPKQKLKEEPDREARAGVQADEDEDGD 295
+ T+K +E+ + + T P ++ +E+P +E +
Sbjct: 925 VSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEGFIRSSEGPKPEKV 984
Query: 296 EKDEKKHRSQPKDLAAKR-----RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTE 350
K + + R P+ + +R RP + P + D K+E E+ +++ ++ TE
Sbjct: 985 YKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKEGEKAEKVTE 1044
Query: 351 KKMARAKTVMNSKTHPP 367
K + + + PP
Sbjct: 1045 KVVVKPEKTEKKDLPPP 1061
Score = 32.3 bits (72), Expect = 3.9
Identities = 34/131 (25%), Positives = 48/131 (36%), Gaps = 17/131 (12%)
Query: 221 RRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEP-D 279
R + S+E + RP E + K G E + EK K P P +EE D
Sbjct: 952 RCIDSKEPIERP----EEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVND 1007
Query: 280 REARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEK 339
R R + D K+E++ R +EKE EK + EK EK
Sbjct: 1008 RPVRRSGPIKKPVLRDMKEEREQR------------KEKEGEKAEKVTEKVVVKPEKTEK 1055
Query: 340 RRKTTPKEPTE 350
+ P P +
Sbjct: 1056 KDLPPPPPPPQ 1066
Score = 32.3 bits (72), Expect = 3.9
Identities = 65/312 (20%), Positives = 110/312 (35%), Gaps = 74/312 (23%)
Query: 118 RRVGMADANSPPKPLSKPRTPRRS------KSDGEAKRSRDPPASASQVTGIRAEPSP-- 169
RR G P +P + R R +S+ +PP Q I A+ P
Sbjct: 1349 RRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEVPKPEDGEPPRRHEQFIPIAADKRPPK 1408
Query: 170 -----SPRITRKSTRQTTITSHFAKGPAKRKPQEESERAKSDE-----------SIKEE- 212
P R ++ T K P R+ +E +KS+E ++ +E
Sbjct: 1409 FERKFDPARERPRRQRPTRPPRQDKPPRFRRLREREAASKSNEVVAVPTNGTVNNVAQEP 1468
Query: 213 ---------DKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRS 263
+K D + + + EE E A + + ERDEK+ L +
Sbjct: 1469 VNTLGDISGNKTPDLSNQNSSDQAN-------EEWETASESSDFNERRERDEKKNADLNA 1521
Query: 264 QTKEPT------PKQKLKEEP-------DREARAGVQADEDEDGD-EKDEKKHRSQPKDL 309
QT PK+++ + DR+ R G + + RS P
Sbjct: 1522 QTVVKVGENVLPPKREIAKRSFSSQRPVDRQNRRGNNGPPKSGRNFSGPRNERRSGPPSK 1581
Query: 310 AAKRRPEEKEP------EKVN----------PQISDEKDEDEKEEKRR---KTTPKEPTE 350
+ KR P + +P + +N P + +K+ + K+R K PK+P E
Sbjct: 1582 SGKRGPFDDQPAGTTGVDLINGSSAHHQEGVPNGTGQKNSKDSTGKKREDPKPGPKKPKE 1641
Query: 351 KKMARAKTVMNS 362
K A ++ +N+
Sbjct: 1642 KVDALSQFDLNN 1653
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 62.4 bits (150), Expect = 3e-09
Identities = 40/139 (28%), Positives = 71/139 (51%), Gaps = 9/139 (6%)
Query: 197 QEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEK 256
+EESE DE ED+DQ+ +R R+ S+++ R ++ + K +KEEE +K
Sbjct: 335 EEESE----DEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKK 390
Query: 257 EEK--RLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRR 314
EEK + K+ +++++ + + E + + DEDEDG +K E + + P +
Sbjct: 391 EEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDP---GTEET 447
Query: 315 PEEKEPEKVNPQISDEKDE 333
E E E ++ D+ DE
Sbjct: 448 YGEVEEEPLDEAQDDDLDE 466
Score = 41.2 bits (95), Expect = 0.008
Identities = 31/143 (21%), Positives = 67/143 (46%), Gaps = 24/143 (16%)
Query: 223 VTSRERVARPLPAEEPER-----AKSGTRTEKEEER-----DEKEEKRLRSQTKEPTPK- 271
+ + RV +P+P A S E E+E +++E +R R +K+ +
Sbjct: 307 IERKVRVPKPIPLPGVRNIIFPFAPSPNEEESEDEEYYSEDEDQEARRHRLHSKDQRKRM 366
Query: 272 ----QKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRPEEKEPEKVNPQI 327
Q++KE+ + E + + + E+ +E++E++ K++ EE+E N +
Sbjct: 367 RAFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEE---------MKQKEEEEEIRNKNEEE 417
Query: 328 SDEKDEDEKEEKRRKTTPKEPTE 350
+ KDE++++E + EP +
Sbjct: 418 GESKDEEDEDEDGGQKPEGEPQQ 440
Score = 35.8 bits (81), Expect = 0.35
Identities = 34/140 (24%), Positives = 64/140 (45%), Gaps = 22/140 (15%)
Query: 268 PTPKQKLKEEPDREARAGVQADEDEDGDEKDEKKHRSQPKDLAAKRRP-----EEKEPEK 322
P+P ++ E+ + + EDED ++ ++HR KD + R +EKE E+
Sbjct: 331 PSPNEEESEDEEYYS-------EDED---QEARRHRLHSKDQRKRMRAFQQEMKEKEEEE 380
Query: 323 VNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSKTHPPKCIQCGQYLD----- 377
+ + +K E+++EE+ + KE E+ + + SK + GQ +
Sbjct: 381 MKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQ 440
Query: 378 DPDLK--YGQHPPDAVDEPQ 395
DP + YG+ + +DE Q
Sbjct: 441 DPGTEETYGEVEEEPLDEAQ 460
Score = 34.7 bits (78), Expect = 0.78
Identities = 29/138 (21%), Positives = 52/138 (37%), Gaps = 6/138 (4%)
Query: 189 KGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARPLPAEEPERAKSGTRTE 248
K + K +EE ++ + E +EE+ Q E+ + ++ EE E G + E
Sbjct: 376 KEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPE 435
Query: 249 KEEERDEKEEKRLRSQTKEPTPK------QKLKEEPDREARAGVQADEDEDGDEKDEKKH 302
E ++D E+ +EP + +L E A Q G +
Sbjct: 436 GEPQQDPGTEETYGEVEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENFLG 495
Query: 303 RSQPKDLAAKRRPEEKEP 320
S P ++RR + + P
Sbjct: 496 ASPPIIQPSRRRNQNRVP 513
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 62.0 bits (149), Expect = 5e-09
Identities = 57/230 (24%), Positives = 99/230 (43%), Gaps = 22/230 (9%)
Query: 137 TPRRSKSDGEAKRSRDPPASASQVTGIRAEPSPSPRITRKSTRQTTITSHFAKGPAKRKP 196
TP + + AK++ P A A G + + + I + AK K
Sbjct: 84 TPGKKAAATPAKKTVTP-AKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKK 142
Query: 197 QEESERAKSD-ESIKEEDKDQDEKRRRVT-SRERVARPLPAEEPERAKSGTRTEKEEERD 254
++ E D E +E+D+D+DE + + + A PA E E + E +E+ D
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDD---EDDEDDD 199
Query: 255 EKEEKRLRSQTKEPTPKQKLKEEPDREARA-GVQADEDEDGDEKDEKKHRSQPKDLAAKR 313
+ EE + E TP + K +A V DEDE+ D++DE
Sbjct: 200 DDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDED------------- 246
Query: 314 RPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMNSK 363
++ E ++ + DE++E+E+EE+ K P + +K+MA+ K +K
Sbjct: 247 -DDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGK-RKKEMAKQKAAPEAK 294
Score = 40.0 bits (92), Expect = 0.018
Identities = 51/272 (18%), Positives = 101/272 (37%), Gaps = 38/272 (13%)
Query: 128 PPKPLSKPRTPRRSKSDGEAKRSRDPPASASQVT-----GIRAEPSPSPRITRKSTRQTT 182
P K P+ D E + +S +V G +A + + ++ T++
Sbjct: 14 PKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVA 73
Query: 183 ITSHFAKGPAKRKPQEESERAKSDESIKEEDKDQDEKRRRVTSRERVARP-LPAEEPERA 241
+ + PAK+ ++A + + ++ VT + V P P +A
Sbjct: 74 VAT-----PAKKAAVTPGKKAAATPA-----------KKTVTPAKAVTTPGKKGATPGKA 117
Query: 242 KSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEPDREARAGVQADEDEDGDEKDEKK 301
T +K K K ++ KE + ++ E+ D E +++ED +++DE +
Sbjct: 118 LVATPGKKGAAIPAKGAKNGKNAKKEDSDEE---EDDDSE-------EDEEDDEDEDEDE 167
Query: 302 HRSQPKDLAAKRRPEEKEPEKVNPQISDEKDEDEKEEKRRKTTPKEPTEKKMARAKTVMN 361
+P + A E E DE DED++++ + E + AK
Sbjct: 168 DEIEPAAMKAAAAAPASEDE------DDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKA 221
Query: 362 SKTHPPKCIQCGQYLDDPDLKYGQHPPDAVDE 393
+K P K + D+ + + D D+
Sbjct: 222 AKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDD 253
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,138,690
Number of Sequences: 37866
Number of extensions: 3733142
Number of successful extensions: 43870
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 500
Number of HSP's successfully gapped in prelim test: 1140
Number of HSP's that attempted gapping in prelim test: 18929
Number of HSP's gapped (non-prelim): 11000
length of query: 1632
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1516
effective length of database: 13,855,062
effective search space: 21004273992
effective search space used: 21004273992
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.