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Search of human proteins with 195222730
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|195222730 F-box only protein 34 [Homo sapiens]
(711 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|195222730 F-box only protein 34 [Homo sapiens] 1462 0.0
gi|40807493 F-box only protein 34 [Homo sapiens] 1462 0.0
gi|122937335 F-box protein 46 [Homo sapiens] 288 1e-77
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 37 0.049
gi|150418009 transforming, acidic coiled-coil containing protein... 33 0.70
gi|45827755 transforming, acidic coiled-coil containing protein ... 33 0.70
gi|45827753 transforming, acidic coiled-coil containing protein ... 33 0.70
gi|11119414 transforming, acidic coiled-coil containing protein ... 33 0.70
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 33 0.92
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 33 0.92
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 33 0.92
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 33 0.92
gi|148368987 kleisin beta isoform 1 [Homo sapiens] 33 1.2
gi|151301137 AT-hook transcription factor [Homo sapiens] 33 1.2
gi|239757103 PREDICTED: similar to fos39347_1 [Homo sapiens] 32 1.6
gi|55749621 pleckstrin homology domain containing, family G, mem... 32 1.6
gi|148368978 kleisin beta isoform 2 [Homo sapiens] 32 2.0
gi|55953110 retinoblastoma protein-binding zinc finger protein i... 31 4.5
gi|20336260 retinoblastoma protein-binding zinc finger protein i... 31 4.5
gi|20336258 retinoblastoma protein-binding zinc finger protein i... 31 4.5
gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens] 31 4.5
gi|45505155 F-box protein 38 isoform a [Homo sapiens] 31 4.5
gi|45545409 F-box protein 38 isoform b [Homo sapiens] 31 4.5
gi|40806209 WW domain containing E3 ubiquitin protein ligase 2 i... 30 5.9
gi|40806207 WW domain containing E3 ubiquitin protein ligase 2 i... 30 5.9
gi|18129690 T-box 4 [Homo sapiens] 30 5.9
gi|169214154 PREDICTED: hypothetical protein [Homo sapiens] 30 7.7
gi|169213511 PREDICTED: hypothetical protein [Homo sapiens] 30 7.7
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] 30 7.7
gi|4758404 FSHD region gene 1 [Homo sapiens] 30 7.7
>gi|195222730 F-box only protein 34 [Homo sapiens]
Length = 711
Score = 1462 bits (3785), Expect = 0.0
Identities = 711/711 (100%), Positives = 711/711 (100%)
Query: 1 MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRK 60
MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRK
Sbjct: 1 MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRK 60
Query: 61 PFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKI 120
PFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKI
Sbjct: 61 PFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKI 120
Query: 121 AFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPF 180
AFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPF
Sbjct: 121 AFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPF 180
Query: 181 ACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSG 240
ACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSG
Sbjct: 181 ACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSG 240
Query: 241 QSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPG 300
QSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPG
Sbjct: 241 QSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPG 300
Query: 301 SLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSP 360
SLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSP
Sbjct: 301 SLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSP 360
Query: 361 KEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHT 420
KEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHT
Sbjct: 361 KEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHT 420
Query: 421 YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPG 480
YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPG
Sbjct: 421 YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPG 480
Query: 481 MLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVES 540
MLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVES
Sbjct: 481 MLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVES 540
Query: 541 TLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKC 600
TLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKC
Sbjct: 541 TLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKC 600
Query: 601 TCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPY 660
TCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPY
Sbjct: 601 TCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPY 660
Query: 661 GPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY 711
GPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY
Sbjct: 661 GPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY 711
>gi|40807493 F-box only protein 34 [Homo sapiens]
Length = 711
Score = 1462 bits (3785), Expect = 0.0
Identities = 711/711 (100%), Positives = 711/711 (100%)
Query: 1 MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRK 60
MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRK
Sbjct: 1 MHLKPYWKLQKKEHPPEVSRETQRTPMNHQKAVNDETCKASHITSSVFPSASLGKASSRK 60
Query: 61 PFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKI 120
PFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKI
Sbjct: 61 PFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWAVVKPGNTKEKI 120
Query: 121 AFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPF 180
AFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPF
Sbjct: 121 AFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQVERMREVNSRCYQPEPF 180
Query: 181 ACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSG 240
ACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSG
Sbjct: 181 ACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLASCSKNCTNSPAIVRFSG 240
Query: 241 QSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPG 300
QSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPG
Sbjct: 241 QSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPG 300
Query: 301 SLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSP 360
SLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSP
Sbjct: 301 SLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSP 360
Query: 361 KEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHT 420
KEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHT
Sbjct: 361 KEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHT 420
Query: 421 YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPG 480
YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPG
Sbjct: 421 YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPG 480
Query: 481 MLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVES 540
MLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVES
Sbjct: 481 MLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVES 540
Query: 541 TLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKC 600
TLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKC
Sbjct: 541 TLPVLEASSWKKQVSHDFLETRFKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKC 600
Query: 601 TCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPY 660
TCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPY
Sbjct: 601 TCCYFKFIIEYYNIRPADSRWVRDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPY 660
Query: 661 GPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY 711
GPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY
Sbjct: 661 GPGYWMCCHRSQKGFPGCKLGLHDNHWVPACHSFNRAIHKKAKGTEAEEEY 711
>gi|122937335 F-box protein 46 [Homo sapiens]
Length = 603
Score = 288 bits (737), Expect = 1e-77
Identities = 216/670 (32%), Positives = 302/670 (45%), Gaps = 133/670 (19%)
Query: 49 PSASLGKASSRKPFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGP--LD 106
PSA+L ++ +P G P+ + S +P + V + AP + +EG LD
Sbjct: 28 PSAALKPSACPEPGGGAEPDHGPAHSENTPPALATEVPASQPAPLLSAAAAGDEGRVLLD 87
Query: 107 IWAVVKPGNTKEKIAFFASHQCS--NRIGSMKIKSSWDIDGRATKRRKKSGDLKKAKVQV 164
W V+KPGNTKEK+AFF +HQC +R SMK+K W D KRR++ D KA
Sbjct: 88 TWYVIKPGNTKEKVAFFVAHQCGGGSRASSMKVKGHWGSDSSKAKRRRRCLDPTKAP--- 144
Query: 165 ERMREVNSRCYQPEPFACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRASALLAS 224
P+P + + +G+ V LSV +MVA +EQRA+ L S
Sbjct: 145 ------------PDPGGREGPPAAEEGPASAGEDVDL---LSVAEMVALVEQRAALALQS 189
Query: 225 CSKNCTNSPAIVRFSGQSRGVPAV---SESYSAPGACEEPTERGNLEVGEPQSEPVRVLD 281
+ T +P + F +G PA SE S G C E + S P + L
Sbjct: 190 YPRPTTPAPVV--FVSAEQGGPAKGVGSERRSGGGDCSRVAEAVAHFEAQRDSPPTKGL- 246
Query: 282 MVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDT--- 338
+++ + PG +FR + GR A + G + P +
Sbjct: 247 ----------RKEERPGPGPGEVRIAFRISNGREPRAPDSGLPSGGGGRPGCAYPGSPGP 296
Query: 339 ----------QVNPVGSVSVDCGPSRADRCSPKEDQAWDGAS------QDCPPLPAGVSF 382
+ + S S D PS + + D+A +G S +D PP P
Sbjct: 297 GARAKDKITCDLYQLISPSRDALPSNVEFLLARADEASEGDSPAPARPEDTPPAPP---- 352
Query: 383 HIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSL 442
P ++ + DV +T + F ++
Sbjct: 353 -------PPPARDCGASGFHVDVVVTGVVDECIFFGKDGTK------------------- 386
Query: 443 TSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTT 502
+ ++E++C++++ E P PG LFFL
Sbjct: 387 -----NVKEETVCLTVSPE-------------EPPPPGQLFFL---------QNRGPDGP 419
Query: 503 KESSEASQLEDAAGGDSASEEKSGSAEPFVLPASSVESTLPVLEASSWKKQVSHDFLETR 562
E A A G D A + +++L L + VSHDFLE R
Sbjct: 420 PEPPPADSPATAPGPDDAE--------------GTADTSLCRLY-----RHVSHDFLEIR 460
Query: 563 FKIQQLLEPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYYNIRPADSRWV 622
FKIQ+LLEP+QYM LP H++VKIF LPT++L ALKCTC +FK IIE + +R DSRW
Sbjct: 461 FKIQRLLEPRQYMLLLPEHVLVKIFSFLPTRALAALKCTCHHFKGIIEAFGVRATDSRWS 520
Query: 623 RDPRYREDPCKQCKKKYVKGDVSLCRWHPKPYCQALPYGPGYWMCCHRSQKGFPGCKLGL 682
RDP YR+DPCKQC+K+Y KGDVSLCRWHPKPY LPYG YWMCC R+ + PGC+LGL
Sbjct: 521 RDPLYRDDPCKQCRKRYEKGDVSLCRWHPKPYHHDLPYGRSYWMCCRRADRETPGCRLGL 580
Query: 683 HDNHWVPACH 692
HDN+WV C+
Sbjct: 581 HDNNWVLPCN 590
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 37.4 bits (85), Expect = 0.049
Identities = 22/90 (24%), Positives = 40/90 (44%), Gaps = 3/90 (3%)
Query: 361 KEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHT 420
K D+ ++ +DCP + ++ D ++ +N YD ++T +P S
Sbjct: 2878 KTDETFENLPKDCPSQDSSITTQTDRFSMDVPVSDLAENDEIYDPQITSPYENVPSQSFF 2937
Query: 421 YSQASELPTDA---VDCMSRELVSLTSRNP 447
S+ S+ TDA S E+ S+T +P
Sbjct: 2938 SSEESKTQTDANHTTSFHSSEVYSVTITSP 2967
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 33.5 bits (75), Expect = 0.70
Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 10/135 (7%)
Query: 417 SSHTYSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCED 476
SS +A L DA S S R R SL T K + P + + ++
Sbjct: 2098 SSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKK-PTETPPVKETQQE 2156
Query: 477 PVPGMLFFLPPGQHLSDYSQLNESTTKESS----EASQLEDAAGGDSASEEKSGSAEPFV 532
P L +P G++L+ ++ + T+ S E + LE A G +A S SAE V
Sbjct: 2157 PDEESL--VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 2214
Query: 533 LPASS---VESTLPV 544
PAS V+++ PV
Sbjct: 2215 PPASGGGRVQNSPPV 2229
>gi|45827755 transforming, acidic coiled-coil containing protein 2
isoform b [Homo sapiens]
Length = 1094
Score = 33.5 bits (75), Expect = 0.70
Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 10/135 (7%)
Query: 417 SSHTYSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCED 476
SS +A L DA S S R R SL T K + P + + ++
Sbjct: 244 SSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKK-PTETPPVKETQQE 302
Query: 477 PVPGMLFFLPPGQHLSDYSQLNESTTKESS----EASQLEDAAGGDSASEEKSGSAEPFV 532
P L +P G++L+ ++ + T+ S E + LE A G +A S SAE V
Sbjct: 303 PDEESL--VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 360
Query: 533 LPASS---VESTLPV 544
PAS V+++ PV
Sbjct: 361 PPASGGGRVQNSPPV 375
>gi|45827753 transforming, acidic coiled-coil containing protein 2
isoform c [Homo sapiens]
Length = 996
Score = 33.5 bits (75), Expect = 0.70
Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 10/135 (7%)
Query: 417 SSHTYSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCED 476
SS +A L DA S S R R SL T K + P + + ++
Sbjct: 176 SSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKK-PTETPPVKETQQE 234
Query: 477 PVPGMLFFLPPGQHLSDYSQLNESTTKESS----EASQLEDAAGGDSASEEKSGSAEPFV 532
P L +P G++L+ ++ + T+ S E + LE A G +A S SAE V
Sbjct: 235 PDEESL--VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 292
Query: 533 LPASS---VESTLPV 544
PAS V+++ PV
Sbjct: 293 PPASGGGRVQNSPPV 307
>gi|11119414 transforming, acidic coiled-coil containing protein 2
isoform d [Homo sapiens]
Length = 1026
Score = 33.5 bits (75), Expect = 0.70
Identities = 39/135 (28%), Positives = 58/135 (42%), Gaps = 10/135 (7%)
Query: 417 SSHTYSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCED 476
SS +A L DA S S R R SL T K + P + + ++
Sbjct: 176 SSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKK-PTETPPVKETQQE 234
Query: 477 PVPGMLFFLPPGQHLSDYSQLNESTTKESS----EASQLEDAAGGDSASEEKSGSAEPFV 532
P L +P G++L+ ++ + T+ S E + LE A G +A S SAE V
Sbjct: 235 PDEESL--VPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVV 292
Query: 533 LPASS---VESTLPV 544
PAS V+++ PV
Sbjct: 293 PPASGGGRVQNSPPV 307
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 33.1 bits (74), Expect = 0.92
Identities = 105/516 (20%), Positives = 184/516 (35%), Gaps = 97/516 (18%)
Query: 54 GKASSRKPFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIW-AVVK 112
GK + P V +SGKSP +S+ + +A + + + EEEG + + A K
Sbjct: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSA-----EPSANTTLVSETEEEGSVPAFGAAAK 187
Query: 113 PGNTKEKIAFFASHQCSNRIGSMKIKSSWDIDG---RATKRRKKSGDLKKAKVQVERMRE 169
PG A +S S+ ++ + +A+ K +KA ++ +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGD 247
Query: 170 VN-----------SRCYQPEPFACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRA 218
V R +PE E S S+S + AG V L+ RA
Sbjct: 248 VTPQVKGGALPPAKRAKKPEE-----ESESSEEGSESEEEAPAGTRSQVKASEKILQVRA 302
Query: 219 SALLASCSKNCTNSPAIVRFSGQSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVR 278
++ A + +PA G S + G EE +E + E + + E
Sbjct: 303 ASAPAKGTPGKGATPA-------PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
Query: 279 VLDMVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAP-- 336
A L+++ + Q S S R+ + A GKT V +A
Sbjct: 356 AK---ALLQAKASGKTSQVGAASAPAKESPRKG--------AAPAPPGKTGPAVAKAQAG 404
Query: 337 ----DTQVNPVGSVSVDCGPSRAD----------RCSPKEDQAWDGASQDCPPLPAGVSF 382
D+Q + S S + P++A +P ++ GA+ PP G +
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP-APPRKTGPA- 462
Query: 383 HIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSL 442
+A+++ G Q S + S+ S+ +A+ M+ V
Sbjct: 463 ---AAQVQVGKQEE--------------------DSRSSSEESDSDREALAAMNAAQVKP 499
Query: 443 TSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTT 502
++P + S + K P PG + P + + + +ES++
Sbjct: 500 LGKSPQVKPASTMGMGPLGKGAGPVP----------PGKVGPATPSAQVGKWEEDSESSS 549
Query: 503 KESSEASQLEDAAGGDSASEEKSGS---AEPFVLPA 535
+ESS++S E A E+ G+ A+P PA
Sbjct: 550 EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 33.1 bits (74), Expect = 0.92
Identities = 105/516 (20%), Positives = 184/516 (35%), Gaps = 97/516 (18%)
Query: 54 GKASSRKPFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIW-AVVK 112
GK + P V +SGKSP +S+ + +A + + + EEEG + + A K
Sbjct: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSA-----EPSANTTLVSETEEEGSVPAFGAAAK 187
Query: 113 PGNTKEKIAFFASHQCSNRIGSMKIKSSWDIDG---RATKRRKKSGDLKKAKVQVERMRE 169
PG A +S S+ ++ + +A+ K +KA ++ +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGD 247
Query: 170 VN-----------SRCYQPEPFACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRA 218
V R +PE E S S+S + AG V L+ RA
Sbjct: 248 VTPQVKGGALPPAKRAKKPEE-----ESESSEEGSESEEEAPAGTRSQVKASEKILQVRA 302
Query: 219 SALLASCSKNCTNSPAIVRFSGQSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVR 278
++ A + +PA G S + G EE +E + E + + E
Sbjct: 303 ASAPAKGTPGKGATPA-------PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
Query: 279 VLDMVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAP-- 336
A L+++ + Q S S R+ + A GKT V +A
Sbjct: 356 AK---ALLQAKASGKTSQVGAASAPAKESPRKG--------AAPAPPGKTGPAVAKAQAG 404
Query: 337 ----DTQVNPVGSVSVDCGPSRAD----------RCSPKEDQAWDGASQDCPPLPAGVSF 382
D+Q + S S + P++A +P ++ GA+ PP G +
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP-APPRKTGPA- 462
Query: 383 HIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSL 442
+A+++ G Q S + S+ S+ +A+ M+ V
Sbjct: 463 ---AAQVQVGKQEE--------------------DSRSSSEESDSDREALAAMNAAQVKP 499
Query: 443 TSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTT 502
++P + S + K P PG + P + + + +ES++
Sbjct: 500 LGKSPQVKPASTMGMGPLGKGAGPVP----------PGKVGPATPSAQVGKWEEDSESSS 549
Query: 503 KESSEASQLEDAAGGDSASEEKSGS---AEPFVLPA 535
+ESS++S E A E+ G+ A+P PA
Sbjct: 550 EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 33.1 bits (74), Expect = 0.92
Identities = 105/516 (20%), Positives = 184/516 (35%), Gaps = 97/516 (18%)
Query: 54 GKASSRKPFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIW-AVVK 112
GK + P V +SGKSP +S+ + +A + + + EEEG + + A K
Sbjct: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSA-----EPSANTTLVSETEEEGSVPAFGAAAK 187
Query: 113 PGNTKEKIAFFASHQCSNRIGSMKIKSSWDIDG---RATKRRKKSGDLKKAKVQVERMRE 169
PG A +S S+ ++ + +A+ K +KA ++ +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGD 247
Query: 170 VN-----------SRCYQPEPFACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRA 218
V R +PE E S S+S + AG V L+ RA
Sbjct: 248 VTPQVKGGALPPAKRAKKPEE-----ESESSEEGSESEEEAPAGTRSQVKASEKILQVRA 302
Query: 219 SALLASCSKNCTNSPAIVRFSGQSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVR 278
++ A + +PA G S + G EE +E + E + + E
Sbjct: 303 ASAPAKGTPGKGATPA-------PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
Query: 279 VLDMVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAP-- 336
A L+++ + Q S S R+ + A GKT V +A
Sbjct: 356 AK---ALLQAKASGKTSQVGAASAPAKESPRKG--------AAPAPPGKTGPAVAKAQAG 404
Query: 337 ----DTQVNPVGSVSVDCGPSRAD----------RCSPKEDQAWDGASQDCPPLPAGVSF 382
D+Q + S S + P++A +P ++ GA+ PP G +
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP-APPRKTGPA- 462
Query: 383 HIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSL 442
+A+++ G Q S + S+ S+ +A+ M+ V
Sbjct: 463 ---AAQVQVGKQEE--------------------DSRSSSEESDSDREALAAMNAAQVKP 499
Query: 443 TSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTT 502
++P + S + K P PG + P + + + +ES++
Sbjct: 500 LGKSPQVKPASTMGMGPLGKGAGPVP----------PGKVGPATPSAQVGKWEEDSESSS 549
Query: 503 KESSEASQLEDAAGGDSASEEKSGS---AEPFVLPA 535
+ESS++S E A E+ G+ A+P PA
Sbjct: 550 EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 33.1 bits (74), Expect = 0.92
Identities = 105/516 (20%), Positives = 184/516 (35%), Gaps = 97/516 (18%)
Query: 54 GKASSRKPFGILSPNVLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIW-AVVK 112
GK + P V +SGKSP +S+ + +A + + + EEEG + + A K
Sbjct: 133 GKTGNSMPHPATGKTVANLLSGKSPRKSA-----EPSANTTLVSETEEEGSVPAFGAAAK 187
Query: 113 PGNTKEKIAFFASHQCSNRIGSMKIKSSWDIDG---RATKRRKKSGDLKKAKVQVERMRE 169
PG A +S S+ ++ + +A+ K +KA ++ +
Sbjct: 188 PGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGD 247
Query: 170 VN-----------SRCYQPEPFACGIEHCSVHYVSDSGDGVYAGRPLSVIQMVAFLEQRA 218
V R +PE E S S+S + AG V L+ RA
Sbjct: 248 VTPQVKGGALPPAKRAKKPEE-----ESESSEEGSESEEEAPAGTRSQVKASEKILQVRA 302
Query: 219 SALLASCSKNCTNSPAIVRFSGQSRGVPAVSESYSAPGACEEPTERGNLEVGEPQSEPVR 278
++ A + +PA G S + G EE +E + E + + E
Sbjct: 303 ASAPAKGTPGKGATPA-------PPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPA 355
Query: 279 VLDMVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAP-- 336
A L+++ + Q S S R+ + A GKT V +A
Sbjct: 356 AK---ALLQAKASGKTSQVGAASAPAKESPRKG--------AAPAPPGKTGPAVAKAQAG 404
Query: 337 ----DTQVNPVGSVSVDCGPSRAD----------RCSPKEDQAWDGASQDCPPLPAGVSF 382
D+Q + S S + P++A +P ++ GA+ PP G +
Sbjct: 405 KREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP-APPRKTGPA- 462
Query: 383 HIDSAELEPGSQTAVKNSNRYDVEMTDELVGLPFSSHTYSQASELPTDAVDCMSRELVSL 442
+A+++ G Q S + S+ S+ +A+ M+ V
Sbjct: 463 ---AAQVQVGKQEE--------------------DSRSSSEESDSDREALAAMNAAQVKP 499
Query: 443 TSRNPDQRKESLCISITVSKVDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTT 502
++P + S + K P PG + P + + + +ES++
Sbjct: 500 LGKSPQVKPASTMGMGPLGKGAGPVP----------PGKVGPATPSAQVGKWEEDSESSS 549
Query: 503 KESSEASQLEDAAGGDSASEEKSGS---AEPFVLPA 535
+ESS++S E A E+ G+ A+P PA
Sbjct: 550 EESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPA 585
>gi|148368987 kleisin beta isoform 1 [Homo sapiens]
Length = 299
Score = 32.7 bits (73), Expect = 1.2
Identities = 19/70 (27%), Positives = 32/70 (45%)
Query: 465 KDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEK 524
++QP ++ C PVP + F PG L +++ EA +L +A+ +A E K
Sbjct: 221 EEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPK 280
Query: 525 SGSAEPFVLP 534
+ V P
Sbjct: 281 ESRSPQQVGP 290
>gi|151301137 AT-hook transcription factor [Homo sapiens]
Length = 1439
Score = 32.7 bits (73), Expect = 1.2
Identities = 47/183 (25%), Positives = 66/183 (36%), Gaps = 37/183 (20%)
Query: 239 SGQSRGVPAVSESYSAPGACEEP-------------TER------GNLEVGEPQSEPVRV 279
SG++ G A +E +P + EP TE G+LEV E R
Sbjct: 85 SGETSGEEAEAEDVDSPASSHEPLAWLPQQGRQLDMTEEEPDGTLGSLEVEEAGESSSR- 143
Query: 280 LDMVAKLESECLKRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQ 339
L A L L+ G P +L + R +A+ QA K + P +
Sbjct: 144 LGYEAGLS---LEGHGNTSPMALGHGQA------RGWVASGEQASGDKLSEHSEVNPSVE 194
Query: 340 VNPVGSVSVDCGPSRADRCSPKEDQAWDGASQDCPP------LPAGVSFHIDSAELEPGS 393
++P S S G D S D W+G + P LP G S H+ S + G
Sbjct: 195 LSPARSWS--SGTVSLDHPSDSLDSTWEGETDGPQPTALAETLPEGPSHHLLSPDGRTGG 252
Query: 394 QTA 396
A
Sbjct: 253 SVA 255
>gi|239757103 PREDICTED: similar to fos39347_1 [Homo sapiens]
Length = 181
Score = 32.3 bits (72), Expect = 1.6
Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 4/91 (4%)
Query: 146 RATKRRKK--SGDLKKAKVQVERM--REVNSRCYQPEPFACGIEHCSVHYVSDSGDGVYA 201
RA+ RK SG + A+ + +++ RE+ RCY AC C VHY + S +
Sbjct: 37 RASGIRKAVLSGPGQSAENETDQVNFREIPPRCYPKHAKACIYFTCKVHYSNSSTEIPEF 96
Query: 202 GRPLSVIQMVAFLEQRASALLASCSKNCTNS 232
L V+ + FL+ L A + C +S
Sbjct: 97 LTALEVLMIQHFLQGAGEELPADRNALCRSS 127
>gi|55749621 pleckstrin homology domain containing, family G, member
3 [Homo sapiens]
Length = 1163
Score = 32.3 bits (72), Expect = 1.6
Identities = 53/256 (20%), Positives = 92/256 (35%), Gaps = 29/256 (11%)
Query: 292 KRQGQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCG 351
K+Q + ++ ++ ++ R++L N K K+ +LE N C
Sbjct: 313 KQQYSIQAKTVEEKRNWTHHIKRLILENHHATIPQKAKEAILEMDSYYPN-----RYRCS 367
Query: 352 PSRADRCSPKEDQAWDGASQDCPPLPAGVSFHIDSAELEPGSQTAVKNSNRYDVEMTDEL 411
P R + +D+ Q + + H+ E +K R + E
Sbjct: 368 PERLKKAWSSQDEVSTNVRQG--RRQSEPTKHLLRQLNEKARAAGMKGKGRRESES---- 421
Query: 412 VGLPFSSHTYSQASELPTDAVDCMSRELVSLTSR---NPDQRKESLCISITV------SK 462
S + + PT MS E +S +P+ E S +
Sbjct: 422 -----SRSSRRPSGRSPTSTEKRMSFESISSLPEVEPDPEAGSEQEVFSAVEGPSAEETP 476
Query: 463 VDKDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASE 522
D + P +L + D G+L PPG + + EST + +S+ E+ GG A++
Sbjct: 477 SDTESPEVLETQLDAHQGLLGMDPPGDMVDFVAA--ESTEDLKALSSEEEEEMGG--AAQ 532
Query: 523 EKSGSAEPFVLPASSV 538
E P VL +SV
Sbjct: 533 EPESLLPPSVLDQASV 548
>gi|148368978 kleisin beta isoform 2 [Homo sapiens]
Length = 605
Score = 32.0 bits (71), Expect = 2.0
Identities = 17/60 (28%), Positives = 29/60 (48%)
Query: 465 KDQPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEK 524
++QP ++ C PVP + F PG L +++ EA +L +A+ +A E K
Sbjct: 221 EEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPK 280
>gi|55953110 retinoblastoma protein-binding zinc finger protein
isoform c [Homo sapiens]
Length = 1481
Score = 30.8 bits (68), Expect = 4.5
Identities = 55/236 (23%), Positives = 86/236 (36%), Gaps = 18/236 (7%)
Query: 249 SESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPGSLSRN--- 305
S S+ P E T G+L S P + L K S K+ G P S +N
Sbjct: 1251 SSSHICPYCNREFTYIGSLNKHAAFSCPKKPLSPPKKKVSHSSKKGGHSSPASSDKNSNS 1310
Query: 306 NSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSPKEDQA 365
N RR + S Q GKT+ + TQV P+ S S + S K +
Sbjct: 1311 NHRRRTADAEIKMQSMQTPLGKTR--ARSSGPTQV-PLPSSSFRSKQNVKFAASVKSKKP 1367
Query: 366 WDGASQDCPPLPAGVSFHIDSAELEP-----GSQTAVKNSNRYDVEMTDELVGLPFSSHT 420
+ ++ P+ H++ + + +Q + K S V + L S
Sbjct: 1368 SSSSLRNSSPIRMAKITHVEGKKPKAVAKNHSAQLSSKTSRSLHVRVQKSKAVLQSKS-- 1425
Query: 421 YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCED 476
+ AS+ TD + SRE S P R L + +S+ ++ S +D
Sbjct: 1426 -TLASKKRTDRFNIKSRE----RSGGPVTRSLQLAAAADLSENKREDGSAKQELKD 1476
>gi|20336260 retinoblastoma protein-binding zinc finger protein
isoform b [Homo sapiens]
Length = 1682
Score = 30.8 bits (68), Expect = 4.5
Identities = 55/236 (23%), Positives = 86/236 (36%), Gaps = 18/236 (7%)
Query: 249 SESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPGSLSRN--- 305
S S+ P E T G+L S P + L K S K+ G P S +N
Sbjct: 1452 SSSHICPYCNREFTYIGSLNKHAAFSCPKKPLSPPKKKVSHSSKKGGHSSPASSDKNSNS 1511
Query: 306 NSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSPKEDQA 365
N RR + S Q GKT+ + TQV P+ S S + S K +
Sbjct: 1512 NHRRRTADAEIKMQSMQTPLGKTR--ARSSGPTQV-PLPSSSFRSKQNVKFAASVKSKKP 1568
Query: 366 WDGASQDCPPLPAGVSFHIDSAELEP-----GSQTAVKNSNRYDVEMTDELVGLPFSSHT 420
+ ++ P+ H++ + + +Q + K S V + L S
Sbjct: 1569 SSSSLRNSSPIRMAKITHVEGKKPKAVAKNHSAQLSSKTSRSLHVRVQKSKAVLQSKS-- 1626
Query: 421 YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCED 476
+ AS+ TD + SRE S P R L + +S+ ++ S +D
Sbjct: 1627 -TLASKKRTDRFNIKSRE----RSGGPVTRSLQLAAAADLSENKREDGSAKQELKD 1677
>gi|20336258 retinoblastoma protein-binding zinc finger protein
isoform a [Homo sapiens]
Length = 1718
Score = 30.8 bits (68), Expect = 4.5
Identities = 55/236 (23%), Positives = 86/236 (36%), Gaps = 18/236 (7%)
Query: 249 SESYSAPGACEEPTERGNLEVGEPQSEPVRVLDMVAKLESECLKRQGQREPGSLSRN--- 305
S S+ P E T G+L S P + L K S K+ G P S +N
Sbjct: 1452 SSSHICPYCNREFTYIGSLNKHAAFSCPKKPLSPPKKKVSHSSKKGGHSSPASSDKNSNS 1511
Query: 306 NSFRRNVGRVLLANSTQADEGKTKKGVLEAPDTQVNPVGSVSVDCGPSRADRCSPKEDQA 365
N RR + S Q GKT+ + TQV P+ S S + S K +
Sbjct: 1512 NHRRRTADAEIKMQSMQTPLGKTR--ARSSGPTQV-PLPSSSFRSKQNVKFAASVKSKKP 1568
Query: 366 WDGASQDCPPLPAGVSFHIDSAELEP-----GSQTAVKNSNRYDVEMTDELVGLPFSSHT 420
+ ++ P+ H++ + + +Q + K S V + L S
Sbjct: 1569 SSSSLRNSSPIRMAKITHVEGKKPKAVAKNHSAQLSSKTSRSLHVRVQKSKAVLQSKS-- 1626
Query: 421 YSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKDQPSILNSCED 476
+ AS+ TD + SRE S P R L + +S+ ++ S +D
Sbjct: 1627 -TLASKKRTDRFNIKSRE----RSGGPVTRSLQLAAAADLSENKREDGSAKQELKD 1677
>gi|150010572 SH3 domain containing ring finger 3 [Homo sapiens]
Length = 882
Score = 30.8 bits (68), Expect = 4.5
Identities = 24/105 (22%), Positives = 47/105 (44%), Gaps = 11/105 (10%)
Query: 56 ASSRKPFGILSPN------VLCSMSGKSPVESSLNVKTKKNAPSATIHQGEEEGPLDIWA 109
A+S +P ++SP V P+ S+ + T N +A ++ GP+ + +
Sbjct: 639 ATSLRPHSVVSPQHSHQPPVQMCPRPAIPLTSAASAITPPNVSAANLNGEAGGGPIGVLS 698
Query: 110 VVKPGNTKEKIAFFASHQCSNRIGSMKIKSSWDIDGRATKRRKKS 154
P NT K+ S + + G +K+ + G +TK++ +S
Sbjct: 699 TSSPTNTGCKLDEKKSEKKEKKSGLLKL-----LAGASTKKKSRS 738
>gi|45505155 F-box protein 38 isoform a [Homo sapiens]
Length = 1113
Score = 30.8 bits (68), Expect = 4.5
Identities = 13/43 (30%), Positives = 22/43 (51%)
Query: 570 EPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYY 612
E + YM L H ++ IFR LP + ++ ++C K + Y
Sbjct: 25 ETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLY 67
>gi|45545409 F-box protein 38 isoform b [Homo sapiens]
Length = 1188
Score = 30.8 bits (68), Expect = 4.5
Identities = 13/43 (30%), Positives = 22/43 (51%)
Query: 570 EPQQYMAFLPHHIMVKIFRLLPTKSLVALKCTCCYFKFIIEYY 612
E + YM L H ++ IFR LP + ++ ++C K + Y
Sbjct: 25 ETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLY 67
>gi|40806209 WW domain containing E3 ubiquitin protein ligase 2
isoform 3 [Homo sapiens]
Length = 335
Score = 30.4 bits (67), Expect = 5.9
Identities = 29/98 (29%), Positives = 39/98 (39%), Gaps = 13/98 (13%)
Query: 295 GQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKK--------GVLEAPDTQV----NP 342
G++ PG+ SR+ +N G LAN T DE T GV P + NP
Sbjct: 208 GEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNP 267
Query: 343 -VGSVSVDCGPSRADRCSPKEDQAWDGASQDCPPLPAG 379
S+ P+ + S Q A+Q LPAG
Sbjct: 268 NTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAG 305
>gi|40806207 WW domain containing E3 ubiquitin protein ligase 2
isoform 1 [Homo sapiens]
Length = 870
Score = 30.4 bits (67), Expect = 5.9
Identities = 29/98 (29%), Positives = 39/98 (39%), Gaps = 13/98 (13%)
Query: 295 GQREPGSLSRNNSFRRNVGRVLLANSTQADEGKTKK--------GVLEAPDTQV----NP 342
G++ PG+ SR+ +N G LAN T DE T GV P + NP
Sbjct: 208 GEQSPGARSRHRQPVKNSGHSGLANGTVNDEPTTATDPEEPSVVGVTSPPAAPLSVTPNP 267
Query: 343 -VGSVSVDCGPSRADRCSPKEDQAWDGASQDCPPLPAG 379
S+ P+ + S Q A+Q LPAG
Sbjct: 268 NTTSLPAPATPAEGEEPSTSGTQQLPAAAQAPDALPAG 305
>gi|18129690 T-box 4 [Homo sapiens]
Length = 545
Score = 30.4 bits (67), Expect = 5.9
Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 19/170 (11%)
Query: 352 PSRADRCSPKEDQAWDGASQDCPPLPAGVSFHIDSAELEPGS---QTAVKNSNRYDVEMT 408
PS +P+E + G+ P AGVS +D P S T+V Y V+
Sbjct: 380 PSYCSEVTPREACMYSGSG----PEIAGVS-GVDDLPPPPLSCNMWTSVSPYTSYSVQTM 434
Query: 409 DELVGLPFSSH--TYSQASELPTDAVDCMSRELVSLTSRNPDQRKESLCISITVSKVDKD 466
+ + PF +H + LPT L + +S+ P S+ ++ S+V +
Sbjct: 435 ETVPYQPFPTHFTATTMMPRLPT---------LSAQSSQPPGNAHFSVYNQLSQSQVRER 485
Query: 467 QPSILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAG 516
PS E +P PP HL+ ++ S T S S L+ +G
Sbjct: 486 GPSASFPRERGLPQGCERKPPSPHLNAANEFLYSQTFSLSRESSLQYHSG 535
>gi|169214154 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 30.0 bits (66), Expect = 7.7
Identities = 18/87 (20%), Positives = 36/87 (41%)
Query: 469 SILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSA 528
S+L+S P P M H++ S + S+T S+ S ++ S S + S
Sbjct: 88 SVLSSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSST 147
Query: 529 EPFVLPASSVESTLPVLEASSWKKQVS 555
F ++ +++ + SS ++
Sbjct: 148 SSFTTSTATTSTSISITSTSSISSSIT 174
>gi|169213511 PREDICTED: hypothetical protein [Homo sapiens]
Length = 737
Score = 30.0 bits (66), Expect = 7.7
Identities = 18/87 (20%), Positives = 36/87 (41%)
Query: 469 SILNSCEDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAGGDSASEEKSGSA 528
S+L+S P P M H++ S + S+T S+ S ++ S S + S
Sbjct: 88 SVLSSTITPAPPMSVLSHHTLHITSNSSTSSSSTTSSTSTSSFITSSFTTSTSITSTSST 147
Query: 529 EPFVLPASSVESTLPVLEASSWKKQVS 555
F ++ +++ + SS ++
Sbjct: 148 SSFTTSTATTSTSISITSTSSISSSIT 174
>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
Length = 3062
Score = 30.0 bits (66), Expect = 7.7
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 10/94 (10%)
Query: 475 EDPVPGMLFFLPPGQHLSDYSQLNESTTKESSEASQLEDAAG-----GDSASEEK--SGS 527
ED +L PP + ++ QL + TKE S ++Q + D S+E G
Sbjct: 2664 EDVPSHVLITAPP---MKEHLQLGVNNTKEKSTSTQKDSPLNDMIQSNDLCSKESISGGG 2720
Query: 528 AEPFVLPASSVESTLPVLEASSWKKQVSHDFLET 561
E S+E+TL +L + +DFL++
Sbjct: 2721 TEISQFTPESIEATLSILSRKHVEDVGKNDFLQS 2754
>gi|4758404 FSHD region gene 1 [Homo sapiens]
Length = 258
Score = 30.0 bits (66), Expect = 7.7
Identities = 22/103 (21%), Positives = 46/103 (44%), Gaps = 12/103 (11%)
Query: 90 NAPSATIHQGEEEGPLDIWAVVKPGNTKEKIAFFASHQCSNRIGSMKIKSSWDIDGRATK 149
N+ + + + GP + W +P K+A AS+ C ++ + DI+ ++
Sbjct: 120 NSDGLVVGRSDAIGPREQW---EPVFQNGKMALLASNSCF-----IRCNEAGDIEAKS-- 169
Query: 150 RRKKSGDLKKAKVQVERMREVNSRCYQPEPFACGIEHCSVHYV 192
K +G+ + K++ RE + PE ++ C ++YV
Sbjct: 170 --KTAGEEEMIKIRSCAERETKKKDDIPEEDKGNVKQCEINYV 210
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,824,693
Number of Sequences: 37866
Number of extensions: 1512088
Number of successful extensions: 3467
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 3439
Number of HSP's gapped (non-prelim): 52
length of query: 711
length of database: 18,247,518
effective HSP length: 109
effective length of query: 602
effective length of database: 14,120,124
effective search space: 8500314648
effective search space used: 8500314648
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.