Guide to the Human Genome
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Search of human proteins with 194306647

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194306647 protein phosphatase 1, regulatory subunit 14D
isoform 2 [Homo sapiens]
         (200 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194306647 protein phosphatase 1, regulatory subunit 14D isofo...   414   e-116
gi|8923226 protein phosphatase 1, regulatory subunit 14D isoform...   180   8e-46
gi|15147250 protein phosphatase 1, regulatory (inhibitor) subuni...    50   1e-06
gi|169216486 PREDICTED: hCG_1742852 [Homo sapiens]                     45   4e-05
gi|169216528 PREDICTED: hCG_1742852 [Homo sapiens]                     45   4e-05
gi|239747074 PREDICTED: hypothetical protein XP_002343911 [Homo ...    42   3e-04
gi|169216761 PREDICTED: hCG_1742852 [Homo sapiens]                     42   3e-04
gi|121583542 mitogen-activated protein kinase kinase kinase 15 [...    41   6e-04
gi|148664240 hypothetical protein LOC146556 isoform 1 [Homo sapi...    41   8e-04
gi|149588643 zinc finger protein 283 [Homo sapiens]                    39   0.004
gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo sa...    36   0.019
gi|239755567 PREDICTED: similar to protein phosphatase 1 regulat...    36   0.019
gi|20162550 protein phosphatase 1 regulatory subunit 14B [Homo s...    36   0.019
gi|228480284 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRN...    36   0.025
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]       35   0.043
gi|19743821 integrin beta 1 isoform 1C-2 precursor [Homo sapiens]      34   0.073
gi|19311006 protein phosphatase 1, regulatory (inhibitor) subuni...    34   0.073
gi|239754969 PREDICTED: hypothetical protein [Homo sapiens]            34   0.073
gi|239749517 PREDICTED: hypothetical protein [Homo sapiens]            34   0.073
gi|239743656 PREDICTED: hypothetical protein XP_002342923 [Homo ...    34   0.073
gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens]      34   0.095
gi|73390140 LIM domain kinase 2 isoform 1 [Homo sapiens]               33   0.12 
gi|117676384 splicing factor, arginine/serine-rich 2, interactin...    32   0.28 
gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sap...    32   0.28 
gi|94536788 THAP domain containing 9 [Homo sapiens]                    31   0.61 
gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]          31   0.80 
gi|209364547 suppressor of S. cerevisiae gcr2 isoform 2 [Homo sa...    31   0.80 
gi|237858664 hypothetical protein LOC123207 isoform b [Homo sapi...    30   1.0  
gi|148839316 NIMA-related kinase 4 [Homo sapiens]                      30   1.4  
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    30   1.8  

>gi|194306647 protein phosphatase 1, regulatory subunit 14D isoform
           2 [Homo sapiens]
          Length = 200

 Score =  414 bits (1064), Expect = e-116
 Identities = 200/200 (100%), Positives = 200/200 (100%)

Query: 1   MLSSSPASCTSPSPDGENPCKKVHWASGRRRTSSTDSESKSHPDSSKIPRSRRPSRLTVK 60
           MLSSSPASCTSPSPDGENPCKKVHWASGRRRTSSTDSESKSHPDSSKIPRSRRPSRLTVK
Sbjct: 1   MLSSSPASCTSPSPDGENPCKKVHWASGRRRTSSTDSESKSHPDSSKIPRSRRPSRLTVK 60

Query: 61  YDRGQLQRWLEMEQWVDAQVQELFQSLALSPRLECSGVIHSLQLLPPGFNRFSCLSSWSS 120
           YDRGQLQRWLEMEQWVDAQVQELFQSLALSPRLECSGVIHSLQLLPPGFNRFSCLSSWSS
Sbjct: 61  YDRGQLQRWLEMEQWVDAQVQELFQSLALSPRLECSGVIHSLQLLPPGFNRFSCLSSWSS 120

Query: 121 WDYGIKQPLLSLRLTWKLSWIYPQRSRRLSWRPFLGTAPAPQRLLSLSCSVNSRNSGDSA 180
           WDYGIKQPLLSLRLTWKLSWIYPQRSRRLSWRPFLGTAPAPQRLLSLSCSVNSRNSGDSA
Sbjct: 121 WDYGIKQPLLSLRLTWKLSWIYPQRSRRLSWRPFLGTAPAPQRLLSLSCSVNSRNSGDSA 180

Query: 181 GLRNKPERPSLAASALPGLP 200
           GLRNKPERPSLAASALPGLP
Sbjct: 181 GLRNKPERPSLAASALPGLP 200


>gi|8923226 protein phosphatase 1, regulatory subunit 14D isoform
          1 [Homo sapiens]
          Length = 145

 Score =  180 bits (456), Expect = 8e-46
 Identities = 86/88 (97%), Positives = 86/88 (97%)

Query: 1  MLSSSPASCTSPSPDGENPCKKVHWASGRRRTSSTDSESKSHPDSSKIPRSRRPSRLTVK 60
          MLSSSPASCTSPSPDGENPCKKVHWASGRRRTSSTDSESKSHPDSSKIPRSRRPSRLTVK
Sbjct: 1  MLSSSPASCTSPSPDGENPCKKVHWASGRRRTSSTDSESKSHPDSSKIPRSRRPSRLTVK 60

Query: 61 YDRGQLQRWLEMEQWVDAQVQELFQSLA 88
          YDRGQLQRWLEMEQWVDAQVQELFQ  A
Sbjct: 61 YDRGQLQRWLEMEQWVDAQVQELFQDQA 88


>gi|15147250 protein phosphatase 1, regulatory (inhibitor) subunit
          14A [Homo sapiens]
          Length = 147

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 24/61 (39%), Positives = 41/61 (67%), Gaps = 1/61 (1%)

Query: 28 GRRRTSSTDSESKSH-PDSSKIPRSRRPSRLTVKYDRGQLQRWLEMEQWVDAQVQELFQS 86
          G+R  S   S S++  P  S     +R +R+TVKYDR +LQR L++E+W+D +++EL++ 
Sbjct: 7  GKRVLSKLQSPSRARGPGGSPGGLQKRHARVTVKYDRRELQRRLDVEKWIDGRLEELYRG 66

Query: 87 L 87
          +
Sbjct: 67 M 67


>gi|169216486 PREDICTED: hCG_1742852 [Homo sapiens]
          Length = 402

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 25/43 (58%), Positives = 30/43 (69%), Gaps = 3/43 (6%)

Query: 83  LFQSLALSPR--LECSGVIHSLQLLPPGFNRFSCLSSWSSWDY 123
           L +S AL+P+  + C   + SLQ LPPGF RFSCLS  SSWDY
Sbjct: 299 LRRSFALAPQAGVRCRD-LDSLQPLPPGFKRFSCLSLPSSWDY 340


>gi|169216528 PREDICTED: hCG_1742852 [Homo sapiens]
          Length = 402

 Score = 45.1 bits (105), Expect = 4e-05
 Identities = 25/43 (58%), Positives = 30/43 (69%), Gaps = 3/43 (6%)

Query: 83  LFQSLALSPR--LECSGVIHSLQLLPPGFNRFSCLSSWSSWDY 123
           L +S AL+P+  + C   + SLQ LPPGF RFSCLS  SSWDY
Sbjct: 299 LRRSFALAPQAGVRCRD-LDSLQPLPPGFKRFSCLSLPSSWDY 340


>gi|239747074 PREDICTED: hypothetical protein XP_002343911 [Homo
           sapiens]
          Length = 402

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 24/43 (55%), Positives = 29/43 (67%), Gaps = 3/43 (6%)

Query: 83  LFQSLALSPR--LECSGVIHSLQLLPPGFNRFSCLSSWSSWDY 123
           L +S AL+P+  + C   + SLQ LPPGF RFSCLS  SSW Y
Sbjct: 299 LRRSFALAPQAGVRCRD-LDSLQPLPPGFKRFSCLSLPSSWGY 340


>gi|169216761 PREDICTED: hCG_1742852 [Homo sapiens]
          Length = 402

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 24/43 (55%), Positives = 29/43 (67%), Gaps = 3/43 (6%)

Query: 83  LFQSLALSPR--LECSGVIHSLQLLPPGFNRFSCLSSWSSWDY 123
           L +S AL+P+  + C   + SLQ LPPGF RFSCLS  SSW Y
Sbjct: 299 LRRSFALAPQAGVRCRD-LDSLQPLPPGFKRFSCLSLPSSWGY 340


>gi|121583542 mitogen-activated protein kinase kinase kinase 15
           [Homo sapiens]
          Length = 788

 Score = 41.2 bits (95), Expect = 6e-04
 Identities = 18/27 (66%), Positives = 20/27 (74%)

Query: 101 SLQLLPPGFNRFSCLSSWSSWDYGIKQ 127
           SLQ LPP F RFSCLS  SSWDY + +
Sbjct: 35  SLQPLPPRFKRFSCLSLQSSWDYSLSK 61


>gi|148664240 hypothetical protein LOC146556 isoform 1 [Homo
           sapiens]
          Length = 440

 Score = 40.8 bits (94), Expect = 8e-04
 Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 4/71 (5%)

Query: 65  QLQRWLEMEQWVDAQVQELFQSLALSPRLECSGV----IHSLQLLPPGFNRFSCLSSWSS 120
           +L + ++ +Q    +V+   +    S  +  +GV    + SLQ LPPGF +FSCL   SS
Sbjct: 333 ELSKAIQYQQHFSRRVKRREKQFPDSRSVAQAGVQWRNLGSLQPLPPGFKQFSCLILPSS 392

Query: 121 WDYGIKQPLLS 131
           WDY    P L+
Sbjct: 393 WDYRSVPPYLA 403


>gi|149588643 zinc finger protein 283 [Homo sapiens]
          Length = 679

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 17/23 (73%), Positives = 17/23 (73%)

Query: 101 SLQLLPPGFNRFSCLSSWSSWDY 123
           SLQ  PPGF  FSCLS  SSWDY
Sbjct: 18  SLQAPPPGFTLFSCLSLLSSWDY 40


>gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo
           sapiens]
          Length = 2342

 Score = 36.2 bits (82), Expect = 0.019
 Identities = 17/23 (73%), Positives = 19/23 (82%), Gaps = 1/23 (4%)

Query: 95  CSGVIHS-LQLLPPGFNRFSCLS 116
           CS ++ S LQLLPPGF RFSCLS
Sbjct: 85  CSAMVPSQLQLLPPGFKRFSCLS 107


>gi|239755567 PREDICTED: similar to protein phosphatase 1
          regulatory subunit 14B [Homo sapiens]
          Length = 147

 Score = 36.2 bits (82), Expect = 0.019
 Identities = 14/33 (42%), Positives = 24/33 (72%)

Query: 52 RRPSRLTVKYDRGQLQRWLEMEQWVDAQVQELF 84
          RR  ++TVKYDR +L++ L +E+W+  Q+  L+
Sbjct: 51 RRQGKVTVKYDRKELRKRLNLEEWILEQLTRLY 83


>gi|20162550 protein phosphatase 1 regulatory subunit 14B [Homo
          sapiens]
          Length = 147

 Score = 36.2 bits (82), Expect = 0.019
 Identities = 14/33 (42%), Positives = 24/33 (72%)

Query: 52 RRPSRLTVKYDRGQLQRWLEMEQWVDAQVQELF 84
          RR  ++TVKYDR +L++ L +E+W+  Q+  L+
Sbjct: 51 RRQGKVTVKYDRKELRKRLNLEEWILEQLTRLY 83


>gi|228480284 Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA
           synthase isoform 3 [Homo sapiens]
          Length = 500

 Score = 35.8 bits (81), Expect = 0.025
 Identities = 16/23 (69%), Positives = 17/23 (73%)

Query: 101 SLQLLPPGFNRFSCLSSWSSWDY 123
           SLQ  PPGF  F+CLS  SSWDY
Sbjct: 8   SLQPPPPGFTPFACLSLPSSWDY 30


>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
          Length = 1243

 Score = 35.0 bits (79), Expect = 0.043
 Identities = 25/84 (29%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 3   SSSPASCTSPSPDGENPCKKVHWASGRRRTSSTDSESKSHPDSSKIPRSRRPSRLTVKYD 62
           S+ P    SP P  + P +   W  G    ++ DS     PDS+  P SR P R+    +
Sbjct: 89  SAGPGPARSPPPSSKEPPEGT-WTEGAPVKAAEDSARPELPDSAVGPGSREPLRVP---E 144

Query: 63  RGQLQRWLEMEQWVDAQVQELFQS 86
              L+R  E E+  D + Q +  S
Sbjct: 145 AVALERRREQEEKEDMETQAVATS 168


>gi|19743821 integrin beta 1 isoform 1C-2 precursor [Homo sapiens]
          Length = 819

 Score = 34.3 bits (77), Expect = 0.073
 Identities = 19/47 (40%), Positives = 27/47 (57%), Gaps = 4/47 (8%)

Query: 84  FQSLALSPRLECSGV----IHSLQLLPPGFNRFSCLSSWSSWDYGIK 126
           F+   ++ + +  GV    I SLQ L   F +FSCLS  S+WDY +K
Sbjct: 766 FEKEKMNAKWDTPGVQWCDISSLQPLTSRFQQFSCLSLPSTWDYRVK 812


>gi|19311006 protein phosphatase 1, regulatory (inhibitor) subunit
          14C [Homo sapiens]
          Length = 165

 Score = 34.3 bits (77), Expect = 0.073
 Identities = 13/35 (37%), Positives = 25/35 (71%)

Query: 50 RSRRPSRLTVKYDRGQLQRWLEMEQWVDAQVQELF 84
          R  +  ++TVKYDR +L++ L +E+W+  Q+ +L+
Sbjct: 65 RRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLY 99


>gi|239754969 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 184

 Score = 34.3 bits (77), Expect = 0.073
 Identities = 14/20 (70%), Positives = 15/20 (75%)

Query: 106 PPGFNRFSCLSSWSSWDYGI 125
           PP F RFSCLS  SSWDY +
Sbjct: 154 PPRFKRFSCLSLPSSWDYRV 173


>gi|239749517 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 184

 Score = 34.3 bits (77), Expect = 0.073
 Identities = 14/20 (70%), Positives = 15/20 (75%)

Query: 106 PPGFNRFSCLSSWSSWDYGI 125
           PP F RFSCLS  SSWDY +
Sbjct: 154 PPRFKRFSCLSLPSSWDYRV 173


>gi|239743656 PREDICTED: hypothetical protein XP_002342923 [Homo
           sapiens]
          Length = 184

 Score = 34.3 bits (77), Expect = 0.073
 Identities = 14/20 (70%), Positives = 15/20 (75%)

Query: 106 PPGFNRFSCLSSWSSWDYGI 125
           PP F RFSCLS  SSWDY +
Sbjct: 154 PPRFKRFSCLSLPSSWDYRV 173


>gi|19743817 integrin beta 1 isoform 1C-1 precursor [Homo sapiens]
          Length = 825

 Score = 33.9 bits (76), Expect = 0.095
 Identities = 16/28 (57%), Positives = 19/28 (67%)

Query: 99  IHSLQLLPPGFNRFSCLSSWSSWDYGIK 126
           I SLQ L   F +FSCLS  S+WDY +K
Sbjct: 791 ISSLQPLTSRFQQFSCLSLPSTWDYRVK 818


>gi|73390140 LIM domain kinase 2 isoform 1 [Homo sapiens]
          Length = 686

 Score = 33.5 bits (75), Expect = 0.12
 Identities = 12/33 (36%), Positives = 23/33 (69%)

Query: 52  RRPSRLTVKYDRGQLQRWLEMEQWVDAQVQELF 84
           RR  ++T+KYD  +L++ L +E+W+  Q+  L+
Sbjct: 590 RRQGKVTIKYDPKELRKHLNLEEWILEQLTRLY 622


>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
           protein [Homo sapiens]
          Length = 1463

 Score = 32.3 bits (72), Expect = 0.28
 Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 5   SPASCTSPSPDGENPCKKVHWASGRRRTSSTDSESKSHPDSSKIPRSRRPSR-LTVKYDR 63
           SP++  SP+ D     K+    S RR T     +S+S    ++  R R+ SR  + K D 
Sbjct: 796 SPSTTWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDI 855

Query: 64  GQLQRWLEMEQWVDAQVQELFQSLALSPRLECS 96
            + +R  +         +E  +S +LSPR E S
Sbjct: 856 ARERRQSQSRSPKRDTTRESRRSESLSPRRETS 888


>gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sapiens]
          Length = 1079

 Score = 32.3 bits (72), Expect = 0.28
 Identities = 15/25 (60%), Positives = 18/25 (72%)

Query: 99   IHSLQLLPPGFNRFSCLSSWSSWDY 123
            + SLQ  PPGF RFS LS  +SW+Y
Sbjct: 1003 LSSLQPPPPGFKRFSHLSLPNSWNY 1027


>gi|94536788 THAP domain containing 9 [Homo sapiens]
          Length = 903

 Score = 31.2 bits (69), Expect = 0.61
 Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 3/53 (5%)

Query: 78  AQVQELFQSLALSPRLECSGVIHSLQLLPPGFNRFSCLSSWSSWDYGIKQPLL 130
           A   E   SL L P   C G IH L+L+    N F   +S + +  G+K PLL
Sbjct: 487 ASALEYLLSLDLPPFQNCIGTIHFLRLIN---NLFDIFNSRNCYGKGLKGPLL 536


>gi|34147532 myosin, light chain 10, regulatory [Homo sapiens]
          Length = 226

 Score = 30.8 bits (68), Expect = 0.80
 Identities = 14/22 (63%), Positives = 19/22 (86%)

Query: 78 AQVQELFQSLALSPRLECSGVI 99
          +Q+QE  +SLALSPRLE +G+I
Sbjct: 50 SQIQEFKESLALSPRLERNGMI 71


>gi|209364547 suppressor of S. cerevisiae gcr2 isoform 2 [Homo
           sapiens]
          Length = 677

 Score = 30.8 bits (68), Expect = 0.80
 Identities = 13/21 (61%), Positives = 14/21 (66%)

Query: 102 LQLLPPGFNRFSCLSSWSSWD 122
           LQ  PPGF  F CLS  S+WD
Sbjct: 387 LQAPPPGFTPFICLSLLSTWD 407


>gi|237858664 hypothetical protein LOC123207 isoform b [Homo
           sapiens]
          Length = 167

 Score = 30.4 bits (67), Expect = 1.0
 Identities = 13/17 (76%), Positives = 16/17 (94%)

Query: 83  LFQSLALSPRLECSGVI 99
           L Q+LALSP+LECSGV+
Sbjct: 132 LRQNLALSPKLECSGVV 148


>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
          Length = 841

 Score = 30.0 bits (66), Expect = 1.4
 Identities = 13/15 (86%), Positives = 14/15 (93%)

Query: 85  QSLALSPRLECSGVI 99
           QSLALSP+LECSG I
Sbjct: 456 QSLALSPKLECSGTI 470


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 29.6 bits (65), Expect = 1.8
 Identities = 30/100 (30%), Positives = 44/100 (44%), Gaps = 10/100 (10%)

Query: 4   SSPASCTSPSPDGENPCKKVHWA------SGRRRTSSTDSESKSHPDS-SKIPRSRRPSR 56
           +S A   S S DGE   +K   +      S     SS+DSES+S P+S S+  R  +   
Sbjct: 743 NSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSSDSESESEPESESESRRVTKEKE 802

Query: 57  LTVKYDRGQLQR---WLEMEQWVDAQVQELFQSLALSPRL 93
              K DR  L +    L+++ +          + ALSP L
Sbjct: 803 KKTKQDRTPLTKDVSLLDLDDFNPVSTPVALPTPALSPSL 842


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,525,514
Number of Sequences: 37866
Number of extensions: 439878
Number of successful extensions: 1742
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 46
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 1677
Number of HSP's gapped (non-prelim): 83
length of query: 200
length of database: 18,247,518
effective HSP length: 97
effective length of query: 103
effective length of database: 14,574,516
effective search space: 1501175148
effective search space used: 1501175148
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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