Guide to the Human Genome
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Search of human proteins with 194306635

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194306635 PRAME family member 19 [Homo sapiens]
         (479 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194306635 PRAME family member 19 [Homo sapiens]                    976   0.0  
gi|153791443 PRAME family member 18 [Homo sapiens]                    972   0.0  
gi|154800493 PRAME family member 22 [Homo sapiens]                    892   0.0  
gi|194306638 PRAME family member 3 [Homo sapiens]                     884   0.0  
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]    660   0.0  
gi|194018546 PRAME family member 10 [Homo sapiens]                    574   e-164
gi|12738831 PRAME family member 1 [Homo sapiens]                      565   e-161
gi|157426839 PRAME family member 17 [Homo sapiens]                    562   e-160
gi|113865933 PRAME family member 16 [Homo sapiens]                    560   e-159
gi|66954681 PRAME family member 13 [Homo sapiens]                     553   e-157
gi|12738834 PRAME family member 2 [Homo sapiens]                      545   e-155
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ...   534   e-152
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ...   534   e-152
gi|153792140 PRAME family member 14 [Homo sapiens]                    486   e-137
gi|124249372 PRAME family member 12 [Homo sapiens]                    468   e-132
gi|153792112 PRAME family member 20 [Homo sapiens]                    454   e-128
gi|153945800 PRAME family member 21 [Homo sapiens]                    454   e-128
gi|239741053 PREDICTED: similar to Putative PRAME family member ...   445   e-125
gi|59676587 PRAME family member 8 [Homo sapiens]                      445   e-125
gi|59676593 PRAME family member 7 [Homo sapiens]                      442   e-124
gi|148356236 PRAME family member 15 [Homo sapiens]                    414   e-116
gi|61102721 PRAME family member 9 [Homo sapiens]                      414   e-116
gi|61696142 PRAME family member 5 [Homo sapiens]                      413   e-115
gi|58219004 PRAME family member 6 [Homo sapiens]                      412   e-115
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]         409   e-114
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]         408   e-114
gi|59958373 PRAME family member 4 [Homo sapiens]                      407   e-114
gi|226437621 PRAME family member 11 [Homo sapiens]                    354   9e-98
gi|46249373 preferentially expressed antigen in melanoma [Homo s...   349   3e-96
gi|46249371 preferentially expressed antigen in melanoma [Homo s...   349   3e-96

>gi|194306635 PRAME family member 19 [Homo sapiens]
          Length = 479

 Score =  976 bits (2522), Expect = 0.0
 Identities = 479/479 (100%), Positives = 479/479 (100%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
           PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
           DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
           NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479


>gi|153791443 PRAME family member 18 [Homo sapiens]
          Length = 479

 Score =  972 bits (2512), Expect = 0.0
 Identities = 478/479 (99%), Positives = 478/479 (99%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
           PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
           DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           IG SKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
           NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479


>gi|154800493 PRAME family member 22 [Homo sapiens]
          Length = 481

 Score =  892 bits (2304), Expect = 0.0
 Identities = 441/479 (92%), Positives = 455/479 (94%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLE+RDVDENFWTIWSGAR
Sbjct: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
           PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E SRYLSQM+NLRKLFIS
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
           DGC YL S +SQ QLVAEFSSV LRLEYLQMLY+RR+ FF G+LDQLIRCL+SPLETLAL
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           TYG L++ DLKCLP YPSLSQLKQLNLSHG LRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I  SKLRVILPALS CSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
           +RGRVISELLTPLQAELMRILREVREP RIFFGPVSCPCCG SPTEQLEFNFCL GRPA
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA 481


>gi|194306638 PRAME family member 3 [Homo sapiens]
          Length = 481

 Score =  884 bits (2284), Expect = 0.0
 Identities = 439/479 (91%), Positives = 453/479 (94%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 3   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLE+RDVDENFWTIWSGAR
Sbjct: 63  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
           PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E  RYLSQM+NLRKLFIS
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
           DGC YL S +SQ QLVAEFSSV LRLEYLQMLY+RR+ FF G+LDQLIRCL+SPLETLAL
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           TYG L++ DLKCLP YPSLSQLKQLNLSHG LRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I  SKLRVILPALS CSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
           +RGRVISELLTPLQAELMRILREVREP RIFFGPVSCPCCG SPTEQLEFNFCL GRPA
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA 481


>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
          Length = 474

 Score =  660 bits (1703), Expect = 0.0
 Identities = 344/469 (73%), Positives = 376/469 (80%), Gaps = 1/469 (0%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1   MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLE+RDVDENFWTIWSGAR
Sbjct: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
           PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E S YLSQM+NLRKLFIS
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
           DGC YL S +SQ Q +A F++ FL+L  LQ LYM  + F EG+LDQL+ CLK+ L+ L +
Sbjct: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L DCG
Sbjct: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I  S++  ILPALSRC  L TF F GN  SM  L++LL HT  L NL LE YPAPRES  
Sbjct: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
             G +     T ++AELM+ +R++R P RI FG   CP CG      LE
Sbjct: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468


>gi|194018546 PRAME family member 10 [Homo sapiens]
          Length = 474

 Score =  574 bits (1479), Expect = e-164
 Identities = 294/473 (62%), Positives = 353/473 (74%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAP RLLELAGQSLLR+Q L I  LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMKT  LE L  V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61  FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE ++DE LS+  GW+ +RR  VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CC+KV NYSM   +FRN+LE +YPDSIQ LE+W  C      + + YLSQM NLR+LF++
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
            G         Q   + +  S FL L Y QMLY+++I   + +L+ L+R LK+PL     
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           +   L + D++CL  YPSLSQLK+L L H  +    LEPL  LLEKVAATL+TL L DC 
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I   +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHTG LS L LE YPAP ESLD
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
            +G V  E+LTP++AELMR LREVR+P RIFFGPV CP CG  P+E+++F+ C
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473


>gi|12738831 PRAME family member 1 [Homo sapiens]
          Length = 474

 Score =  565 bits (1457), Expect = e-161
 Identities = 297/473 (62%), Positives = 348/473 (73%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+  LF+EAF+ R  + L VMVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F CLPLGSLMKT  LE L  +++G+  LL QK RPRRWKLQVL++RDVDENFW  W GA 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LSC PE  SKRQT EDCPR GE QPLKVF+D+CLKE   DE L +   WV  RR  VHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CC+K+VNY   I   R  L+ +Y +SIQ LEI NM WP ++ ++  YL +MKNLRKL  S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
               Y    E QG+LVA+FSSVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           TYG L EED+KCL  YPSL  LK LNLS+  L  I LEPL ALLEK+AA+L+TL L  C 
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I YS+L  ILPALSRCS LTTF F  N  S+D LKDLLRHT  LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           +  RV  E+ TPL+AELM  LREVR+P RIF GP  CP CG SP+E+LE + C
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473


>gi|157426839 PRAME family member 17 [Homo sapiens]
          Length = 474

 Score =  562 bits (1448), Expect = e-160
 Identities = 291/473 (61%), Positives = 349/473 (73%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS Q+P RLLELAGQSLLR+Q L I +LDELPRE+FP +F+EA + R  E LK+MVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMKTP LE L  V+ G+D LLAQK+RPRRWKLQVL++RDVD NFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE ++DE LS+   W+ +RR  VHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CC KV NYSM   +FRN+L+ VYPDSIQ LEI   C      + + YLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
            G         Q Q V +    FL L Y QMLY+R+I   + +L+ L+RCLK+PL T   
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
            +  L ++D++CL  YPSLSQLK+L+L H  +    LEPL ALLEKVAATL+ L L DC 
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I  S+LRV+LPALSRCS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           NRG V  E+L P++AELM  LREVR+P RIFFGP+ CP CG  P+E+++F+ C
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473


>gi|113865933 PRAME family member 16 [Homo sapiens]
          Length = 474

 Score =  560 bits (1443), Expect = e-159
 Identities = 290/473 (61%), Positives = 348/473 (73%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS Q+P RLLELAGQSLLR+Q L I +LDELPRE+FP +F+EA + R  E LK+MVQAWP
Sbjct: 1   MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMKTP LE L  V+ G+D LLAQK+RPRRWKLQVL++RDVD NFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE ++DE LS+   W+ +RR  VHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CC KV NYSM   +FRN+L+ VYPDSIQ LEI   C      + + YLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
            G         Q Q V +    FL L Y QMLY+R+I   + +L+ L+RCLK+PL T   
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
            +  L ++D++CL  YPSLSQLK+L+L H  +    LEPL ALLEKVAATL+ L L DC 
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I  S+LRV+LPALSRCS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           NRG V  E+L P++AELM  LREVR+P RIFFGP+ CP CG  P+E+++F+ C
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473


>gi|66954681 PRAME family member 13 [Homo sapiens]
          Length = 474

 Score =  553 bits (1425), Expect = e-157
 Identities = 291/473 (61%), Positives = 343/473 (72%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+  LF+EAF  R  + L VMVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F CLPLGSLMKT  LE L  +++G+  LL QK RPRRWKLQVL++RDVDENFW  W GA 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE   DE L +   WV  RR  VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CC+K+VNY   I + R  L+ +Y +SIQ LEI NM WP ++ ++  YL +MKNLRKL  S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
                +   E +G+LV +FSSVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           TYG L EED+KCL  YPSL  LK LNLS+  L  I LEPL ALLEK+AA+L+TL L  C 
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I YS+L  ILP LS CS LTTF F  N  SM  LKDLLRHT  LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           +  RV  E+   L+AELM  LREVR+P RIF GP  CP CG SP+E+LE + C
Sbjct: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473


>gi|12738834 PRAME family member 2 [Homo sapiens]
          Length = 474

 Score =  545 bits (1404), Expect = e-155
 Identities = 289/473 (61%), Positives = 340/473 (71%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+  LF EAF+ R  + L VMVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F CLPL SLMKT  LE L  +++G+  LL QK RPRRWKLQVL++RDVDENFW  W GA 
Sbjct: 61  FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE   DE L +   WV  RR  VHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CC+K+VNY   I   R  L+ +Y +SI  LEI N CWP ++ ++  YL +MK L KL  S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
               Y    E +G LV  F+SVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           T G+L EEDLKCL  +PSL  LK LNLS+  L  I LEPL ALLEK+AA+L+TL L  C 
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I YS+L  ILP LS CS LTTF F  N  S+D LKDLLRHT  LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           +  RV  E+ TPL+AELM  LRE R+P RIF GP  CP CG SP+E+LE + C
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473


>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
           sapiens]
          Length = 426

 Score =  534 bits (1376), Expect = e-152
 Identities = 280/473 (59%), Positives = 329/473 (69%), Gaps = 48/473 (10%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAP RLLELAGQSLLR+Q L I  LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMKTP LE L  V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE ++DE LS+  GW+ +RR  VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CC+KV NYSM   +FRN+LE +YPDSIQ LE+W  C      + + YLSQM NLR+LF  
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
                                                           R LK+PL     
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           +   L + D++CL  YPSLSQLK+L L H  +    LEPL  LLEKVAATL+TL L DC 
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I   +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT  LS L LE YPAP ESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
            +G V  E+LTP++AELMR LREVR+P RIFFGPV CP CG  P+E+++F+ C
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425


>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
           sapiens]
          Length = 426

 Score =  534 bits (1375), Expect = e-152
 Identities = 280/473 (59%), Positives = 329/473 (69%), Gaps = 48/473 (10%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAP RLLELAGQSLLR+Q L I  LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1   MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMKTP LE L  V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61  FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE ++DE LS+  GW+ +RR  VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CC+KV NYSM   +FRN+LE +YPDSIQ LE+W  C      + + YLSQM NLR+LF  
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
                                                           R LK+PL     
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           +   L + D++CL  YPSLSQLK+L L H  +    LEPL  LLEKVAATL+TL L DC 
Sbjct: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I   +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT  LS L LE YPAP ESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
            +G V  E+LTP++AELMR LREVR+P RIFFGPV CP CG  P+E+++F+ C
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425


>gi|153792140 PRAME family member 14 [Homo sapiens]
          Length = 426

 Score =  486 bits (1251), Expect = e-137
 Identities = 266/473 (56%), Positives = 308/473 (65%), Gaps = 48/473 (10%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+  LF+EAF  R  + L VMVQAWP
Sbjct: 1   MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F CLPLGSLMKT  LE L  +++G+  LL QK RPRRWKLQVL++RDVDENFW  W GA 
Sbjct: 61  FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE   DE L +   WV  RR  VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
           CC+K+VNY   I + R  L+ +Y +SIQ LEI NM WP ++ ++  YL +MKNLRKL  S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240

Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
                                                           RCL++PLE L L
Sbjct: 241 ------------------------------------------------RCLQNPLENLEL 252

Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
           TYG L EED+KCL  YPSL  LK LNLS+  L  I LEPL ALLEK+AA+L+TL L  C 
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312

Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
           I YS+L  ILP LS CS LTTF F  N  SM  LKDLL HT  LS LSLETYPAP ESL+
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372

Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           +  RV  E+   L+AELM  LREVR+P RIF GP  CP CG SP+E+LE + C
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425


>gi|124249372 PRAME family member 12 [Homo sapiens]
          Length = 483

 Score =  468 bits (1205), Expect = e-132
 Identities = 260/481 (54%), Positives = 328/481 (68%), Gaps = 15/481 (3%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS QAP RLLELA QSLLRD+ALAI  L+ELPRELFP LF+EAFT R CE L  MVQAWP
Sbjct: 1   MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F CLPLGSLMK+ +LEI   V++G+D LLAQKVRPRRWKLQVL++R+VDENFW IWSGA 
Sbjct: 61  FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
            LS  PEA+SKR+T  +CPR G +QPL V +D+C K   +DE L+ F  W + R+  +H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
           CC ++  + + I     +L TV  D IQ +E+   C P  ++ + R   YL QM+NLRKL
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235

Query: 238 FISD----GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKS 293
            + +     C  +P  + + Q V +F+S FL+L+Y Q LYM  + F EG+LDQL+RCL++
Sbjct: 236 VLFNIHVSAC--IP-LDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQA 292

Query: 294 PLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQT 353
           PLET+ +T   L E DLK L W PS+ QLK+L+L   TL     EPL  LLE+  ATLQT
Sbjct: 293 PLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQT 352

Query: 354 LFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYP 413
           L L DCGI  S+L  ILPALSRCS L+TF F GN  SM  L++LLRHT  LS LSLE YP
Sbjct: 353 LDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYP 412

Query: 414 APRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           AP ES D +G +     + L AELM+ LR++R+P  I F  V CP CG+  +  LE + C
Sbjct: 413 APLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHC 472

Query: 474 L 474
           L
Sbjct: 473 L 473


>gi|153792112 PRAME family member 20 [Homo sapiens]
          Length = 475

 Score =  454 bits (1169), Expect = e-128
 Identities = 254/474 (53%), Positives = 311/474 (65%), Gaps = 2/474 (0%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS + P RLLELAG+SLLRD+ALAIS L+ELP ELFP LF+EAF+ R CE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMK P  E    V+DG+D LL  +VR RRWKLQVL+++DV ENFW +WS A 
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
              C P AM  R+ V+DCPR   +QPL VF+D+CLK +++DE  +    WV+ R   VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
           CC K+    M   N RNIL+TV  D IQ +E+ N  W   ++AE + YL QM+NLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239

Query: 240 SDGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLA 299
           SD      S E + + V +F++ FL+L  LQ LYM  + F EG+LDQ++ CLK+ L  LA
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299

Query: 300 LTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDC 359
           +T   L E DLK L  YPS+ QLK L+LS   L    L PL+ LLEKVAATL+ L L DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359

Query: 360 GIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 419
           GI  S++  ILPALSRC  LTTF F GN  S   L++LL HT RL+NL LE YPAPRES 
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419

Query: 420 DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           D RG V       L AELM  +R +REP RI F    CP CG      LE + C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473


>gi|153945800 PRAME family member 21 [Homo sapiens]
          Length = 475

 Score =  454 bits (1169), Expect = e-128
 Identities = 254/474 (53%), Positives = 311/474 (65%), Gaps = 2/474 (0%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS + P RLLELAG+SLLRD+ALAIS L+ELP ELFP LF+EAF+ R CE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMK P  E    V+DG+D LL  +VR RRWKLQVL+++DV ENFW +WS A 
Sbjct: 61  FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
              C P AM  R+ V+DCPR   +QPL VF+D+CLK +++DE  +    WV+ R   VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
           CC K+    M   N RNIL+TV  D IQ +E+ N  W   ++AE + YL QM+NLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239

Query: 240 SDGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLA 299
           SD      S E + + V +F++ FL+L  LQ LYM  + F EG+LDQ++ CLK+ L  LA
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299

Query: 300 LTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDC 359
           +T   L E DLK L  YPS+ QLK L+LS   L    L PL+ LLEKVAATL+ L L DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359

Query: 360 GIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 419
           GI  S++  ILPALSRC  LTTF F GN  S   L++LL HT RL+NL LE YPAPRES 
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419

Query: 420 DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           D RG V       L AELM  +R +REP RI F    CP CG      LE + C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473


>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
           [Homo sapiens]
          Length = 474

 Score =  445 bits (1144), Expect = e-125
 Identities = 247/479 (51%), Positives = 325/479 (67%), Gaps = 11/479 (2%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS +AP RLLELA Q LLRDQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMK+P LE L  V++G+D LL Q+VRPR+ KLQVL++R+VDENF  I+SGA 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
             +  PEA+S++QT ++CP TG +QP  VF+D+CLK +++DE L+    W + R+  +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
           CC ++  + M I +   +L  V  D IQ +E+   C P  ++ + +   YL QM+NLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235

Query: 238 FISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPL 295
            + +      +P  +++GQ +A F+S FL+L+Y Q L M  + F EG+LDQL+RCL++ L
Sbjct: 236 VLFNIRASACIPP-DNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294

Query: 296 ETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLF 355
           E + +T   L E DLK L W PS+ QLK+L+L   TL     EPL  LLE+V ATLQTL 
Sbjct: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354

Query: 356 LVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 415
           L DCGI  S+L  ILP LSRCS L+TF F GN  SM  L++LLRHT  LS LSLE YPAP
Sbjct: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414

Query: 416 RESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCL 474
            ES D +G +       L AELM+ LR++R+P  I F  V CP CG+  +  LE + CL
Sbjct: 415 LESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473


>gi|59676587 PRAME family member 8 [Homo sapiens]
          Length = 474

 Score =  445 bits (1144), Expect = e-125
 Identities = 247/479 (51%), Positives = 325/479 (67%), Gaps = 11/479 (2%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS +AP RLLELA Q LLRDQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMK+P LE L  V++G+D LL Q+VRPR+ KLQVL++R+VDENF  I+SGA 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
             +  PEA+S++QT ++CP TG +QP  VF+D+CLK +++DE L+    W + R+  +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
           CC ++  + M I +   +L  V  D IQ +E+   C P  ++ + +   YL QM+NLRKL
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235

Query: 238 FISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPL 295
            + +      +P  +++GQ +A F+S FL+L+Y Q L M  + F EG+LDQL+RCL++ L
Sbjct: 236 VLFNIRASACIPP-DNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294

Query: 296 ETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLF 355
           E + +T   L E DLK L W PS+ QLK+L+L   TL     EPL  LLE+V ATLQTL 
Sbjct: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354

Query: 356 LVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 415
           L DCGI  S+L  ILP LSRCS L+TF F GN  SM  L++LLRHT  LS LSLE YPAP
Sbjct: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414

Query: 416 RESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCL 474
            ES D +G +       L AELM+ LR++R+P  I F  V CP CG+  +  LE + CL
Sbjct: 415 LESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473


>gi|59676593 PRAME family member 7 [Homo sapiens]
          Length = 474

 Score =  442 bits (1137), Expect = e-124
 Identities = 246/479 (51%), Positives = 324/479 (67%), Gaps = 11/479 (2%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS +AP RLLELA Q LLRDQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1   MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPLGSLMK+P LE L  V++G+D LL Q+VRPR+ KLQVL++R+VDENF  I+SGA 
Sbjct: 61  FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
             +  PEA+S++QT ++CP TG +QP  VF+D+CLK +++DE L+    W + R+  +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
           CC ++  + M I +   +L  V  D IQ +E+   C P  ++ + +   YL QM+NLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235

Query: 238 FISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPL 295
            + +      +P  +++GQ +A F+S FL+L+Y Q L M  + F EG+LDQL+RCL++ L
Sbjct: 236 VLFNIRASACIPP-DNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294

Query: 296 ETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLF 355
           E + +T   L E DLK L W PS+ QLK+L+L   TL     EPL  LLE+V ATLQTL 
Sbjct: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354

Query: 356 LVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 415
           L DCGI  S+L  ILP LSRCS L+TF F GN  SM  L++LLRHT  LS LSLE YPAP
Sbjct: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414

Query: 416 RESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCL 474
            ES D +G +       L AELM+  R++R+P  I F  V CP CG+  +  LE + CL
Sbjct: 415 LESYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473


>gi|148356236 PRAME family member 15 [Homo sapiens]
          Length = 478

 Score =  414 bits (1065), Expect = e-116
 Identities = 236/472 (50%), Positives = 306/472 (64%), Gaps = 5/472 (1%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPL  L+K P LE    V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A 
Sbjct: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
              C   A   ++ V+DCPR   +QPL VF+++ LK +++DE L++   WV+ R+  +HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241

Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
           S  D   Y+ S E + ++V +F++ FL+L  LQ LYM  + F EG+LDQL+ CLK+ L+ 
Sbjct: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300

Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360

Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
           DCGI  S++  ILPALSRC  L TF F GN   M  L++LL HT  L NL +E YPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420

Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
           S    G +       ++AELM  +R++R P RI F    CP CG      LE
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472


>gi|61102721 PRAME family member 9 [Homo sapiens]
          Length = 478

 Score =  414 bits (1065), Expect = e-116
 Identities = 236/472 (50%), Positives = 306/472 (64%), Gaps = 5/472 (1%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 3   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPL  L+K P LE    V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A 
Sbjct: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
              C   A   ++ V+DCPR   +QPL VF+++ LK +++DE L++   WV+ R+  +HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241

Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
           S  D   Y+ S E + ++V +F++ FL+L  LQ LYM  + F EG+LDQL+ CLK+ L+ 
Sbjct: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300

Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360

Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
           DCGI  S++  ILPALSRC  L TF F GN   M  L++LL HT  L NL +E YPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420

Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
           S    G +       ++AELM  +R++R P RI F    CP CG      LE
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472


>gi|61696142 PRAME family member 5 [Homo sapiens]
          Length = 476

 Score =  413 bits (1061), Expect = e-115
 Identities = 237/476 (49%), Positives = 308/476 (64%), Gaps = 5/476 (1%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPL  L+K P LE    V+DG+D LL Q V PRRWKLQVL+++DV ENFW +WS A 
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
              C   A   ++ V+DCPR   +QPL VF+++ LK +++DE L+    WV+ R+  +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239

Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
           S  D   Y+ S E + ++V +F++ FL+L  LQ L M  + F EG+LDQL+ CLK+ L+ 
Sbjct: 240 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298

Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358

Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
           DCGI  S++  ILPALSRC  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418

Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           S D  G +       ++AELM+ +R++R P RI F    CP CG      LE + C
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474


>gi|58219004 PRAME family member 6 [Homo sapiens]
          Length = 476

 Score =  412 bits (1060), Expect = e-115
 Identities = 237/476 (49%), Positives = 307/476 (64%), Gaps = 5/476 (1%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPL  L+K P LE    V+DG+D LL Q V PRRWKLQVL+++DV ENFW +WS A 
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
              C   A   +  V+DCPR   +QPL VF+++ LK +++DE L+    WV+ R+  +HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239

Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
           S  D   Y+ S E + ++V +F++ FL+L  LQ L M  + F EG+LDQL+ CLK+ L+ 
Sbjct: 240 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298

Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358

Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
           DCGI  S++  ILPALSRC  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418

Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           S D  G +       ++AELM+ +R++R P RI F    CP CG      LE + C
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474


>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
          Length = 476

 Score =  409 bits (1052), Expect = e-114
 Identities = 236/476 (49%), Positives = 307/476 (64%), Gaps = 5/476 (1%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1   MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPL  L+K P LE    V+DG+D LL Q V PRRWKLQVL+++DV ENFW +WS A 
Sbjct: 61  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
              C   A   ++ V+DCPR   +QPL VF+++ LK +++DE L+    WV+ R+  +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239

Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
           S  D   Y+ S E + ++V +F++ FL+L  LQ L M  + F EG+LDQL+ CLK+ L+ 
Sbjct: 240 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298

Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358

Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
           DCGI  S++  ILPALS C  L TF F GN  SM  L++LL HT  L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418

Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
           S D  G +       ++AELM+ +R++R P RI F    CP CG      LE + C
Sbjct: 419 SYDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474


>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
          Length = 513

 Score =  408 bits (1049), Expect = e-114
 Identities = 232/461 (50%), Positives = 301/461 (65%), Gaps = 5/461 (1%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS + P RLLEL G+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 38  MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPL  L+K P LE    V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A 
Sbjct: 98  FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
              C   A   +  V+DCPR  E+QPL VF+++ LK +++DE L+    WV+ RR  +HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  ++NL+KL +
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276

Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
           S  D   Y+ S E + ++V +F++ FL+L  LQ LYM  + F EG+LDQL+ CLK+ L+ 
Sbjct: 277 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335

Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395

Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
           DCGI  S++  ILPALSRC  L TF F GN   M  L++LL HT  L NL LE YPAP+E
Sbjct: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455

Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCP 458
           S    G +       ++AELM+ +R +R P RI F   +CP
Sbjct: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 496


>gi|59958373 PRAME family member 4 [Homo sapiens]
          Length = 478

 Score =  407 bits (1047), Expect = e-114
 Identities = 235/472 (49%), Positives = 303/472 (64%), Gaps = 5/472 (1%)

Query: 1   MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
           MS   P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQ+WP
Sbjct: 3   MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62

Query: 61  FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
           F  LPL  L+K P LE    V+DG+D LL   VRPRRWKLQVL+++DV ENFW +WS A 
Sbjct: 63  FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122

Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
              C   A   ++ VEDCPR   +QPL VF+++ LK +++DE L+    WV+ R+  +HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182

Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
           CC K+    M   N R+IL+ V  D IQ +E+ N  W   ++ + + YL  M+NL+KL +
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241

Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
           S  D   Y+ S E + ++V +F++ FL+L  LQ LYM  + F EG+LDQL+ CLK+ L+ 
Sbjct: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300

Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
           L +T   L E DLK L   PS+SQLK L+LS   L    L PL+ LLEKVAATL+ L L 
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360

Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
           DCGI  S++  ILPALSRC  L TF F GN   M  L++LL HT  L NL +E YPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420

Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
           S    G +       ++AELM  +R++R P RI F    CP CG      LE
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472


>gi|226437621 PRAME family member 11 [Homo sapiens]
          Length = 436

 Score =  354 bits (909), Expect = 9e-98
 Identities = 203/421 (48%), Positives = 268/421 (63%), Gaps = 5/421 (1%)

Query: 41  VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKL 100
           +EAF+ RRCE LK+MVQAWPF  LPL  L+K P LE    V+DG+D LL Q VRPRRWKL
Sbjct: 1   MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60

Query: 101 QVLEMRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSV 160
           QVL+++DV ENFW +WS A    C   A   +  V+DCPR  E+QPL VF+++ LK +++
Sbjct: 61  QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120

Query: 161 DEDLSFFSGWVQHRRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC- 219
           DE L+    WV+ RR  +HLCC K+    M   N R+IL+ V  D IQ +E+ N  W   
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179

Query: 220 MVAEVSRYLSQMKNLRKLFIS--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRI 277
           ++ + + YL  ++NL+KL +S  D   Y+ S E + ++V +F++ FL+L  LQ LYM  +
Sbjct: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSV 238

Query: 278 RFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRL 337
            F EG+LDQL+ CLK+ L+ L +T   L E DLK L   PS+SQLK L+LS   L    L
Sbjct: 239 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 298

Query: 338 EPLRALLEKVAATLQTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDL 397
            PL+ LLEKVAATL+ L L DCGI  S++  ILPALSRC  L TF F GN   M  L++L
Sbjct: 299 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 358

Query: 398 LRHTGRLSNLSLETYPAPRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSC 457
           L HT  L NL LE YPAP+ES    G +       ++AELM+ +R +R P RI F   +C
Sbjct: 359 LSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNC 418

Query: 458 P 458
           P
Sbjct: 419 P 419


>gi|46249373 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  349 bits (896), Expect = 3e-96
 Identities = 214/471 (45%), Positives = 294/471 (62%), Gaps = 15/471 (3%)

Query: 5   APRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWPFPCL 64
           +PRRL+ELAGQSLL+D+ALAI+ L+ LPRELFP LF+ AF  R  + LK MVQAWPF CL
Sbjct: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81

Query: 65  PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLEMR-DVDENFWTIWSGARP 121
           PLG LMK   L  E    V+DG+D LLAQ+VRPRRWKLQVL++R +  ++FWT+WSG R 
Sbjct: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141

Query: 122 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKSVDEDLSFFSGWVQH 173
              S   PEA   M+K++ V+      E+   P++V +D+ LKE + DE  S+    V+ 
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201

Query: 174 RRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKN 233
           ++  + LCC K+  ++M + + + IL+ V  DSI+ LE+        +A+ S YL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261

Query: 234 LRKLFISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCL 291
           LR+L +S      Y+ S E + Q +A+F+S FL L+ LQ LY+  + F  G LDQL+R +
Sbjct: 262 LRRLLLSHIHASSYI-SPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320

Query: 292 KSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATL 351
            +PLETL++T   L E D+  L   PS+SQL  L+LS   L  +  EPL+ALLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380

Query: 352 QTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLET 411
           Q L   +CGI   +L  +LP+LS CS LTT  F+GN  S+  L+ LL+H   LSNL+   
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440

Query: 412 YPAPRESL-DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCG 461
           YP P ES  D  G +  E L  L A L  +L E+  P+ ++     CP CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491


>gi|46249371 preferentially expressed antigen in melanoma [Homo
           sapiens]
          Length = 509

 Score =  349 bits (896), Expect = 3e-96
 Identities = 214/471 (45%), Positives = 294/471 (62%), Gaps = 15/471 (3%)

Query: 5   APRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWPFPCL 64
           +PRRL+ELAGQSLL+D+ALAI+ L+ LPRELFP LF+ AF  R  + LK MVQAWPF CL
Sbjct: 22  SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81

Query: 65  PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLEMR-DVDENFWTIWSGARP 121
           PLG LMK   L  E    V+DG+D LLAQ+VRPRRWKLQVL++R +  ++FWT+WSG R 
Sbjct: 82  PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141

Query: 122 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKSVDEDLSFFSGWVQH 173
              S   PEA   M+K++ V+      E+   P++V +D+ LKE + DE  S+    V+ 
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201

Query: 174 RRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKN 233
           ++  + LCC K+  ++M + + + IL+ V  DSI+ LE+        +A+ S YL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261

Query: 234 LRKLFISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCL 291
           LR+L +S      Y+ S E + Q +A+F+S FL L+ LQ LY+  + F  G LDQL+R +
Sbjct: 262 LRRLLLSHIHASSYI-SPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320

Query: 292 KSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATL 351
            +PLETL++T   L E D+  L   PS+SQL  L+LS   L  +  EPL+ALLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380

Query: 352 QTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLET 411
           Q L   +CGI   +L  +LP+LS CS LTT  F+GN  S+  L+ LL+H   LSNL+   
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440

Query: 412 YPAPRESL-DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCG 461
           YP P ES  D  G +  E L  L A L  +L E+  P+ ++     CP CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,072,419
Number of Sequences: 37866
Number of extensions: 780379
Number of successful extensions: 2486
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2352
Number of HSP's gapped (non-prelim): 64
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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