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Search of human proteins with 194306635
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194306635 PRAME family member 19 [Homo sapiens]
(479 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194306635 PRAME family member 19 [Homo sapiens] 976 0.0
gi|153791443 PRAME family member 18 [Homo sapiens] 972 0.0
gi|154800493 PRAME family member 22 [Homo sapiens] 892 0.0
gi|194306638 PRAME family member 3 [Homo sapiens] 884 0.0
gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens] 660 0.0
gi|194018546 PRAME family member 10 [Homo sapiens] 574 e-164
gi|12738831 PRAME family member 1 [Homo sapiens] 565 e-161
gi|157426839 PRAME family member 17 [Homo sapiens] 562 e-160
gi|113865933 PRAME family member 16 [Homo sapiens] 560 e-159
gi|66954681 PRAME family member 13 [Homo sapiens] 553 e-157
gi|12738834 PRAME family member 2 [Homo sapiens] 545 e-155
gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo ... 534 e-152
gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo ... 534 e-152
gi|153792140 PRAME family member 14 [Homo sapiens] 486 e-137
gi|124249372 PRAME family member 12 [Homo sapiens] 468 e-132
gi|153792112 PRAME family member 20 [Homo sapiens] 454 e-128
gi|153945800 PRAME family member 21 [Homo sapiens] 454 e-128
gi|239741053 PREDICTED: similar to Putative PRAME family member ... 445 e-125
gi|59676587 PRAME family member 8 [Homo sapiens] 445 e-125
gi|59676593 PRAME family member 7 [Homo sapiens] 442 e-124
gi|148356236 PRAME family member 15 [Homo sapiens] 414 e-116
gi|61102721 PRAME family member 9 [Homo sapiens] 414 e-116
gi|61696142 PRAME family member 5 [Homo sapiens] 413 e-115
gi|58219004 PRAME family member 6 [Homo sapiens] 412 e-115
gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens] 409 e-114
gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens] 408 e-114
gi|59958373 PRAME family member 4 [Homo sapiens] 407 e-114
gi|226437621 PRAME family member 11 [Homo sapiens] 354 9e-98
gi|46249373 preferentially expressed antigen in melanoma [Homo s... 349 3e-96
gi|46249371 preferentially expressed antigen in melanoma [Homo s... 349 3e-96
>gi|194306635 PRAME family member 19 [Homo sapiens]
Length = 479
Score = 976 bits (2522), Expect = 0.0
Identities = 479/479 (100%), Positives = 479/479 (100%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
>gi|153791443 PRAME family member 18 [Homo sapiens]
Length = 479
Score = 972 bits (2512), Expect = 0.0
Identities = 478/479 (99%), Positives = 478/479 (99%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS
Sbjct: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL
Sbjct: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
IG SKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 361 IGDSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA
Sbjct: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
>gi|154800493 PRAME family member 22 [Homo sapiens]
Length = 481
Score = 892 bits (2304), Expect = 0.0
Identities = 441/479 (92%), Positives = 455/479 (94%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLE+RDVDENFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLELRDVDENFWTIWSGAR 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E SRYLSQM+NLRKLFIS
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSRYLSQMRNLRKLFIS 242
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
DGC YL S +SQ QLVAEFSSV LRLEYLQMLY+RR+ FF G+LDQLIRCL+SPLETLAL
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
TYG L++ DLKCLP YPSLSQLKQLNLSHG LRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I SKLRVILPALS CSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
+RGRVISELLTPLQAELMRILREVREP RIFFGPVSCPCCG SPTEQLEFNFCL GRPA
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA 481
>gi|194306638 PRAME family member 3 [Homo sapiens]
Length = 481
Score = 884 bits (2284), Expect = 0.0
Identities = 439/479 (91%), Positives = 453/479 (94%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 3 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLE+RDVDENFWTIWSGAR
Sbjct: 63 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 123 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 182
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E RYLSQM+NLRKLFIS
Sbjct: 183 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFIRYLSQMRNLRKLFIS 242
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
DGC YL S +SQ QLVAEFSSV LRLEYLQMLY+RR+ FF G+LDQLIRCL+SPLETLAL
Sbjct: 243 DGCRYLLSSDSQEQLVAEFSSVLLRLEYLQMLYVRRVCFFRGHLDQLIRCLRSPLETLAL 302
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
TYG L++ DLKCLP YPSLSQLKQLNLSHG LRFIRLEPLRALLEKVAATLQTLFLVDCG
Sbjct: 303 TYGFLEKVDLKCLPRYPSLSQLKQLNLSHGALRFIRLEPLRALLEKVAATLQTLFLVDCG 362
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I SKLRVILPALS CSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD
Sbjct: 363 IRDSKLRVILPALSCCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 422
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCLRGRPA 479
+RGRVISELLTPLQAELMRILREVREP RIFFGPVSCPCCG SPTEQLEFNFCL GRPA
Sbjct: 423 DRGRVISELLTPLQAELMRILREVREPKRIFFGPVSCPCCGTSPTEQLEFNFCLWGRPA 481
>gi|239741047 PREDICTED: PRAME family member 25-like [Homo sapiens]
Length = 474
Score = 660 bits (1703), Expect = 0.0
Identities = 344/469 (73%), Positives = 376/469 (80%), Gaps = 1/469 (0%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAPRRLLELAGQSLL DQALAIS+LDELPRELFP LFVEAFTSRRCEVLKVMVQAWP
Sbjct: 1 MSLQAPRRLLELAGQSLLGDQALAISILDELPRELFPPLFVEAFTSRRCEVLKVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRR KLQVLE+RDVDENFWTIWSGAR
Sbjct: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRRKLQVLELRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEK +DEDLSFFSGWVQHRR SVHL
Sbjct: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKFMDEDLSFFSGWVQHRRGSVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CCTKVVNYSM+ILNFRNILETVYPDSIQVLEIWNMCWPCM+ E S YLSQM+NLRKLFIS
Sbjct: 181 CCTKVVNYSMSILNFRNILETVYPDSIQVLEIWNMCWPCMIVEFSPYLSQMRNLRKLFIS 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
DGC YL S +SQ Q +A F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+ L +
Sbjct: 241 DGCRYLLSSDSQEQ-IAPFTTQFLKLHCLQKLYMNSVSFLEGHLDQLLSCLKTSLKVLTI 299
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L DCG
Sbjct: 300 TNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLDDCG 359
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I S++ ILPALSRC L TF F GN SM L++LL HT L NL LE YPAPRES
Sbjct: 360 IIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCLELYPAPRESYG 419
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
G + T ++AELM+ +R++R P RI FG CP CG LE
Sbjct: 420 ADGTLCWSRFTQIRAELMKRVRDLRHPKRILFGTDYCPDCGNRSFYDLE 468
>gi|194018546 PRAME family member 10 [Homo sapiens]
Length = 474
Score = 574 bits (1479), Expect = e-164
Identities = 294/473 (62%), Positives = 353/473 (74%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAP RLLELAGQSLLR+Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMKT LE L V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61 FLSLPLGSLMKTLHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LSCSPEAMSKRQTVEDCPR GE QPLKVF+D+CLKE ++DE LS+ GW+ +RR VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C + + YLSQM NLR+LF++
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLA 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
G Q + + S FL L Y QMLY+++I + +L+ L+R LK+PL
Sbjct: 241 FGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIF 300
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
+ L + D++CL YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 301 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 360
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHTG LS L LE YPAP ESLD
Sbjct: 361 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTGGLSKLGLELYPAPLESLD 420
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
+G V E+LTP++AELMR LREVR+P RIFFGPV CP CG P+E+++F+ C
Sbjct: 421 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPNCGSWPSEKVDFHLC 473
>gi|12738831 PRAME family member 1 [Homo sapiens]
Length = 474
Score = 565 bits (1457), Expect = e-161
Identities = 297/473 (62%), Positives = 348/473 (73%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF+EAF+ R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFSRRHFQTLTVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LSC PE SKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 ALSCFPETTSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CC+K+VNY I R L+ +Y +SIQ LEI NM WP ++ ++ YL +MKNLRKL S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYLNSIQELEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Y E QG+LVA+FSSVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 RCHHYTSDNELQGRLVAKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
TYG L EED+KCL YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLKTLILEGCQ 360
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I YS+L ILPALSRCS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPALSRCSQLTTFYFGRNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
+ RV E+ TPL+AELM LREVR+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|157426839 PRAME family member 17 [Homo sapiens]
Length = 474
Score = 562 bits (1448), Expect = e-160
Identities = 291/473 (61%), Positives = 349/473 (73%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS Q+P RLLELAGQSLLR+Q L I +LDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRRWKLQVL++RDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LSCSPEAMSKRQTVED PRTGE QPLKVF+D+C KE ++DE LS+ W+ +RR VHL
Sbjct: 121 ALSCSPEAMSKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CC KV NYSM +FRN+L+ VYPDSIQ LEI C + + YLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
G Q Q V + FL L Y QMLY+R+I + +L+ L+RCLK+PL T
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
+ L ++D++CL YPSLSQLK+L+L H + LEPL ALLEKVAATL+ L L DC
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I S+LRV+LPALSRCS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
NRG V E+L P++AELM LREVR+P RIFFGP+ CP CG P+E+++F+ C
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|113865933 PRAME family member 16 [Homo sapiens]
Length = 474
Score = 560 bits (1443), Expect = e-159
Identities = 290/473 (61%), Positives = 348/473 (73%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS Q+P RLLELAGQSLLR+Q L I +LDELPRE+FP +F+EA + R E LK+MVQAWP
Sbjct: 1 MSLQSPSRLLELAGQSLLRNQFLTIFILDELPREVFPLMFMEASSMRHFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D LLAQK+RPRRWKLQVL++RDVD NFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLKGLDTLLAQKLRPRRWKLQVLDLRDVDGNFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LSCSPEAM KRQTVED PRTGE QPLKVF+D+C KE ++DE LS+ W+ +RR VHL
Sbjct: 121 ALSCSPEAMRKRQTVEDYPRTGEHQPLKVFIDLCQKESTLDECLSYLCRWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CC KV NYSM +FRN+L+ VYPDSIQ LEI C + + YLSQM NLRKLF++
Sbjct: 181 CCNKVQNYSMPTSSFRNLLKRVYPDSIQELEIKRKCSLNKTGKFAPYLSQMSNLRKLFLA 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
G Q Q V + FL L Y QMLY+R+I + +L+ L+RCLK+PL T
Sbjct: 241 FGYDDELYVSGQQQFVPDLDCPFLCLYYPQMLYIRKISNIKEHLEHLLRCLKNPLGTFIF 300
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
+ L ++D++CL YPSLSQLK+L+L H + LEPL ALLEKVAATL+ L L DC
Sbjct: 301 CHAYLADQDMECLSQYPSLSQLKELHLIHILMWTTNLEPLGALLEKVAATLEILTLKDCQ 360
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I S+LRV+LPALSRCS LTTF F GN+TS + LKDLL HTG LS L LE YPAP E LD
Sbjct: 361 IQDSQLRVLLPALSRCSQLTTFYFRGNETSTNALKDLLCHTGGLSKLGLELYPAPLECLD 420
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
NRG V E+L P++AELM LREVR+P RIFFGP+ CP CG P+E+++F+ C
Sbjct: 421 NRGHVNWEILAPIRAELMCTLREVRQPKRIFFGPIPCPSCGSWPSEKVDFHLC 473
>gi|66954681 PRAME family member 13 [Homo sapiens]
Length = 474
Score = 553 bits (1425), Expect = e-157
Identities = 291/473 (61%), Positives = 343/473 (72%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF+EAF R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP ++ ++ YL +MKNLRKL S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
+ E +G+LV +FSSVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 RCHHSMSDNELEGRLVTKFSSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
TYG L EED+KCL YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 360
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I YS+L ILP LS CS LTTF F N SM LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
+ RV E+ L+AELM LREVR+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|12738834 PRAME family member 2 [Homo sapiens]
Length = 474
Score = 545 bits (1404), Expect = e-155
Identities = 289/473 (61%), Positives = 340/473 (71%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF EAF+ R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFREAFSRRHFQTLTVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F CLPL SLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FTCLPLVSLMKTLHLEPLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LSC PEAMSKRQT EDCPRTGE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 ALSCFPEAMSKRQTAEDCPRTGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CC+K+VNY I R L+ +Y +SI LEI N CWP ++ ++ YL +MK L KL S
Sbjct: 181 CCSKLVNYLTPIKYLRKSLKIIYINSIGELEIHNTCWPHLIRKLYCYLKEMKTLCKLVFS 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
Y E +G LV F+SVFLRLE+LQ+L ++ I FF G+L+QLIRCL++PLE L L
Sbjct: 241 RCHHYTSDNELEGWLVTRFTSVFLRLEHLQLLKIKLITFFSGHLEQLIRCLQNPLENLEL 300
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
T G+L EEDLKCL +PSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 301 TCGNLLEEDLKCLSQFPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLVLEGCQ 360
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I YS+L ILP LS CS LTTF F N S+D LKDLLRHT LS LSLETYPAP ESL+
Sbjct: 361 IHYSQLSAILPGLSCCSQLTTFYFGSNCMSIDALKDLLRHTSGLSKLSLETYPAPEESLN 420
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
+ RV E+ TPL+AELM LRE R+P RIF GP CP CG SP+E+LE + C
Sbjct: 421 SLVRVNWEIFTPLRAELMCTLREFRQPKRIFIGPTPCPSCGSSPSEELELHLC 473
>gi|239741051 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 534 bits (1376), Expect = e-152
Identities = 280/473 (59%), Positives = 329/473 (69%), Gaps = 48/473 (10%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAP RLLELAGQSLLR+Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE ++DE LS+ GW+ +RR VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C + + YLSQM NLR+LF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
R LK+PL
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
+ L + D++CL YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 253 SDAYLTDRDMECLSQYPSLSQLKELRLIHILMWTTNLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT LS L LE YPAP ESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
+G V E+LTP++AELMR LREVR+P RIFFGPV CP CG P+E+++F+ C
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
>gi|239741055 PREDICTED: similar to PRAME family member 10 [Homo
sapiens]
Length = 426
Score = 534 bits (1375), Expect = e-152
Identities = 280/473 (59%), Positives = 329/473 (69%), Gaps = 48/473 (10%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAP RLLELAGQSLLR+Q L I LDELPRE+FP +F+EAF+ RR E LK+MVQAWP
Sbjct: 1 MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMKTP LE L V+ G+D L+AQKVRPRRWKLQVL++RDVDENFWTIWSGAR
Sbjct: 61 FLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLRDVDENFWTIWSGAR 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LSCSPEAMSKRQTVEDCPR GE+QPLKVF+D+CLKE ++DE LS+ GW+ +RR VHL
Sbjct: 121 VLSCSPEAMSKRQTVEDCPRMGERQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CC+KV NYSM +FRN+LE +YPDSIQ LE+W C + + YLSQM NLR+LF
Sbjct: 181 CCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFFP 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
R LK+PL
Sbjct: 241 ------------------------------------------------RYLKNPLGAFIF 252
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
+ L + D++CL YPSLSQLK+L L H + LEPL LLEKVAATL+TL L DC
Sbjct: 253 SDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTHLEPLGVLLEKVAATLKTLVLKDCR 312
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I +LRV+LPALS CS LTTF FHGN+TSM+ LKDLLRHT LS L LE YPAP ESLD
Sbjct: 313 IQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLD 372
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
+G V E+LTP++AELMR LREVR+P RIFFGPV CP CG P+E+++F+ C
Sbjct: 373 YKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLC 425
>gi|153792140 PRAME family member 14 [Homo sapiens]
Length = 426
Score = 486 bits (1251), Expect = e-137
Identities = 266/473 (56%), Positives = 308/473 (65%), Gaps = 48/473 (10%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAP RLLELAGQSLLRDQAL+IS ++ELPR L+ LF+EAF R + L VMVQAWP
Sbjct: 1 MSIQAPPRLLELAGQSLLRDQALSISAMEELPRVLYLPLFMEAFRRRHFQTLTVMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F CLPLGSLMKT LE L +++G+ LL QK RPRRWKLQVL++RDVDENFW W GA
Sbjct: 61 FTCLPLGSLMKTLHLETLKALLEGLHMLLTQKDRPRRWKLQVLDLRDVDENFWARWPGAW 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LSC PE MSKRQT EDCPR GE QPLKVF+D+CLKE DE L + WV RR VHL
Sbjct: 121 ALSCFPETMSKRQTAEDCPRMGEHQPLKVFIDICLKEIPQDECLRYLFQWVYQRRGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKNLRKLFIS 240
CC+K+VNY I + R L+ +Y +SIQ LEI NM WP ++ ++ YL +MKNLRKL S
Sbjct: 181 CCSKLVNYLTPIKHLRKSLKIIYLNSIQQLEIRNMSWPRLIRKLRCYLKEMKNLRKLVFS 240
Query: 241 DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLAL 300
RCL++PLE L L
Sbjct: 241 ------------------------------------------------RCLQNPLENLEL 252
Query: 301 TYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDCG 360
TYG L EED+KCL YPSL LK LNLS+ L I LEPL ALLEK+AA+L+TL L C
Sbjct: 253 TYGYLLEEDMKCLSQYPSLGYLKHLNLSYVLLFRISLEPLGALLEKIAASLETLILEGCQ 312
Query: 361 IGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESLD 420
I YS+L ILP LS CS LTTF F N SM LKDLL HT LS LSLETYPAP ESL+
Sbjct: 313 IHYSQLSAILPGLSHCSQLTTFYFGRNCMSMGALKDLLCHTSGLSKLSLETYPAPEESLN 372
Query: 421 NRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
+ RV E+ L+AELM LREVR+P RIF GP CP CG SP+E+LE + C
Sbjct: 373 SLVRVDWEIFALLRAELMCTLREVRQPKRIFIGPTPCPSCGSSPSEELELHLC 425
>gi|124249372 PRAME family member 12 [Homo sapiens]
Length = 483
Score = 468 bits (1205), Expect = e-132
Identities = 260/481 (54%), Positives = 328/481 (68%), Gaps = 15/481 (3%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS QAP RLLELA QSLLRD+ALAI L+ELPRELFP LF+EAFT R CE L MVQAWP
Sbjct: 1 MSLQAPPRLLELAEQSLLRDRALAIPTLEELPRELFPPLFMEAFTRRCCETLTTMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F CLPLGSLMK+ +LEI V++G+D LLAQKVRPRRWKLQVL++R+VDENFW IWSGA
Sbjct: 61 FTCLPLGSLMKSCNLEIFRAVLEGLDALLAQKVRPRRWKLQVLDLRNVDENFWGIWSGAS 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
LS PEA+SKR+T +CPR G +QPL V +D+C K +DE L+ F W + R+ +H+
Sbjct: 121 ALS--PEALSKRRTAGNCPRPGGQQPLMVILDLCFKNGMLDECLTHFLEWGKQRKGLLHV 178
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
CC ++ + + I +L TV D IQ +E+ C P ++ + R YL QM+NLRKL
Sbjct: 179 CCKELQIFGIAIHRIIEVLNTVELDCIQEVEV---CCPWELSILIRFAPYLGQMRNLRKL 235
Query: 238 FISD----GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKS 293
+ + C +P + + Q V +F+S FL+L+Y Q LYM + F EG+LDQL+RCL++
Sbjct: 236 VLFNIHVSAC--IP-LDRKEQFVIQFTSQFLKLDYFQKLYMHSVSFLEGHLDQLLRCLQA 292
Query: 294 PLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQT 353
PLET+ +T L E DLK L W PS+ QLK+L+L TL EPL LLE+ ATLQT
Sbjct: 293 PLETVVMTECLLSESDLKHLSWCPSIRQLKELDLRGITLTHFSPEPLSVLLEQAEATLQT 352
Query: 354 LFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYP 413
L L DCGI S+L ILPALSRCS L+TF F GN SM L++LLRHT LS LSLE YP
Sbjct: 353 LDLEDCGIVDSQLSAILPALSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYP 412
Query: 414 APRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
AP ES D +G + + L AELM+ LR++R+P I F V CP CG+ + LE + C
Sbjct: 413 APLESYDAQGALCWGRFSQLGAELMKTLRDLRQPKIIVFSTVPCPRCGIRASYDLEPSHC 472
Query: 474 L 474
L
Sbjct: 473 L 473
>gi|153792112 PRAME family member 20 [Homo sapiens]
Length = 475
Score = 454 bits (1169), Expect = e-128
Identities = 254/474 (53%), Positives = 311/474 (65%), Gaps = 2/474 (0%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS + P RLLELAG+SLLRD+ALAIS L+ELP ELFP LF+EAF+ R CE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMK P E V+DG+D LL +VR RRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
C P AM R+ V+DCPR +QPL VF+D+CLK +++DE + WV+ R VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
CC K+ M N RNIL+TV D IQ +E+ N W ++AE + YL QM+NLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 SDGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLA 299
SD S E + + V +F++ FL+L LQ LYM + F EG+LDQ++ CLK+ L LA
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 300 LTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDC 359
+T L E DLK L YPS+ QLK L+LS L L PL+ LLEKVAATL+ L L DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 360 GIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 419
GI S++ ILPALSRC LTTF F GN S L++LL HT RL+NL LE YPAPRES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 420 DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
D RG V L AELM +R +REP RI F CP CG LE + C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473
>gi|153945800 PRAME family member 21 [Homo sapiens]
Length = 475
Score = 454 bits (1169), Expect = e-128
Identities = 254/474 (53%), Positives = 311/474 (65%), Gaps = 2/474 (0%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS + P RLLELAG+SLLRD+ALAIS L+ELP ELFP LF+EAF+ R CE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDEALAISTLEELPTELFPPLFMEAFSRRHCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMK P E V+DG+D LL +VR RRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FLRLPLGSLMKRPCPETFQAVLDGLDALLTHRVRLRRWKLQVLDLQDVSENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
C P AM R+ V+DCPR +QPL VF+D+CLK +++DE + WV+ R VHL
Sbjct: 121 ARRCLPNAMMNRKPVQDCPRMRGQQPLTVFIDLCLKNRTLDEYFTCLFLWVKQREGLVHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
CC K+ M N RNIL+TV D IQ +E+ N W ++AE + YL QM+NLRKL +
Sbjct: 181 CCKKLKMLGMLFHNIRNILKTVNLDCIQEVEV-NCNWTLPVLAEFTPYLGQMRNLRKLVL 239
Query: 240 SDGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLETLA 299
SD S E + + V +F++ FL+L LQ LYM + F EG+LDQ++ CLK+ L LA
Sbjct: 240 SDIDSRYISPEQKKEFVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQMLSCLKTSLNILA 299
Query: 300 LTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLVDC 359
+T L E DLK L YPS+ QLK L+LS L L PL+ LLEKVAATL+ L L DC
Sbjct: 300 ITNCVLLESDLKHLSKYPSIGQLKTLDLSGTRLANFSLVPLQVLLEKVAATLEYLDLDDC 359
Query: 360 GIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRESL 419
GI S++ ILPALSRC LTTF F GN S L++LL HT RL+NL LE YPAPRES
Sbjct: 360 GIVDSQVNAILPALSRCFELTTFSFRGNPISTATLENLLCHTIRLNNLCLELYPAPRESY 419
Query: 420 DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
D RG V L AELM +R +REP RI F CP CG LE + C
Sbjct: 420 DVRGIVCRSRFAQLGAELMGRVRALREPERILFCTDYCPQCGNRSLYDLEVDRC 473
>gi|239741053 PREDICTED: similar to Putative PRAME family member 24
[Homo sapiens]
Length = 474
Score = 445 bits (1144), Expect = e-125
Identities = 247/479 (51%), Positives = 325/479 (67%), Gaps = 11/479 (2%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS +AP RLLELA Q LLRDQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL++R+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
+ PEA+S++QT ++CP TG +QP VF+D+CLK +++DE L+ W + R+ +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
CC ++ + M I + +L V D IQ +E+ C P ++ + + YL QM+NLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 238 FISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPL 295
+ + +P +++GQ +A F+S FL+L+Y Q L M + F EG+LDQL+RCL++ L
Sbjct: 236 VLFNIRASACIPP-DNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294
Query: 296 ETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLF 355
E + +T L E DLK L W PS+ QLK+L+L TL EPL LLE+V ATLQTL
Sbjct: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354
Query: 356 LVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 415
L DCGI S+L ILP LSRCS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414
Query: 416 RESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCL 474
ES D +G + L AELM+ LR++R+P I F V CP CG+ + LE + CL
Sbjct: 415 LESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
>gi|59676587 PRAME family member 8 [Homo sapiens]
Length = 474
Score = 445 bits (1144), Expect = e-125
Identities = 247/479 (51%), Positives = 325/479 (67%), Gaps = 11/479 (2%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS +AP RLLELA Q LLRDQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL++R+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
+ PEA+S++QT ++CP TG +QP VF+D+CLK +++DE L+ W + R+ +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
CC ++ + M I + +L V D IQ +E+ C P ++ + + YL QM+NLRKL
Sbjct: 179 CCQELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 238 FISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPL 295
+ + +P +++GQ +A F+S FL+L+Y Q L M + F EG+LDQL+RCL++ L
Sbjct: 236 VLFNIRASACIPP-DNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294
Query: 296 ETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLF 355
E + +T L E DLK L W PS+ QLK+L+L TL EPL LLE+V ATLQTL
Sbjct: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354
Query: 356 LVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 415
L DCGI S+L ILP LSRCS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414
Query: 416 RESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCL 474
ES D +G + L AELM+ LR++R+P I F V CP CG+ + LE + CL
Sbjct: 415 LESYDTQGALCWGRFAELGAELMKTLRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
>gi|59676593 PRAME family member 7 [Homo sapiens]
Length = 474
Score = 442 bits (1137), Expect = e-124
Identities = 246/479 (51%), Positives = 324/479 (67%), Gaps = 11/479 (2%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS +AP RLLELA Q LLRDQALAIS ++ELPRELFP LF+EAF+ RRCE LK MVQAWP
Sbjct: 1 MSIRAPPRLLELARQRLLRDQALAISTMEELPRELFPTLFMEAFSRRRCETLKTMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPLGSLMK+P LE L V++G+D LL Q+VRPR+ KLQVL++R+VDENF I+SGA
Sbjct: 61 FTRLPLGSLMKSPHLESLKSVLEGVDVLLTQEVRPRQSKLQVLDLRNVDENFCDIFSGAT 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
+ PEA+S++QT ++CP TG +QP VF+D+CLK +++DE L+ W + R+ +H+
Sbjct: 121 --ASFPEALSQKQTADNCPGTGRQQPFMVFIDLCLKNRTLDECLTHLLEWGKQRKGLLHV 178
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSR---YLSQMKNLRKL 237
CC ++ + M I + +L V D IQ +E+ C P ++ + + YL QM+NLRKL
Sbjct: 179 CCKELQVFGMPIHSIIEVLNMVELDCIQEVEV---CCPWELSTLVKFAPYLGQMRNLRKL 235
Query: 238 FISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPL 295
+ + +P +++GQ +A F+S FL+L+Y Q L M + F EG+LDQL+RCL++ L
Sbjct: 236 VLFNIRASACIPP-DNKGQFIARFTSQFLKLDYFQNLSMHSVSFLEGHLDQLLRCLQASL 294
Query: 296 ETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLF 355
E + +T L E DLK L W PS+ QLK+L+L TL EPL LLE+V ATLQTL
Sbjct: 295 EMVVMTDCLLSESDLKHLSWCPSIRQLKELDLRGVTLTHFSPEPLTGLLEQVVATLQTLD 354
Query: 356 LVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAP 415
L DCGI S+L ILP LSRCS L+TF F GN SM L++LLRHT LS LSLE YPAP
Sbjct: 355 LEDCGIMDSQLSAILPVLSRCSQLSTFSFCGNLISMAALENLLRHTVGLSKLSLELYPAP 414
Query: 416 RESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFCL 474
ES D +G + L AELM+ R++R+P I F V CP CG+ + LE + CL
Sbjct: 415 LESYDTQGALCWGRFAELGAELMKTPRDLRQPKIIVFCTVPCPRCGIRASYDLEPSHCL 473
>gi|148356236 PRAME family member 15 [Homo sapiens]
Length = 478
Score = 414 bits (1065), Expect = e-116
Identities = 236/472 (50%), Positives = 306/472 (64%), Gaps = 5/472 (1%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
C A ++ V+DCPR +QPL VF+++ LK +++DE L++ WV+ R+ +HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL M+NL+KL +
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
S D Y+ S E + ++V +F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+
Sbjct: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
DCGI S++ ILPALSRC L TF F GN M L++LL HT L NL +E YPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
S G + ++AELM +R++R P RI F CP CG LE
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
>gi|61102721 PRAME family member 9 [Homo sapiens]
Length = 478
Score = 414 bits (1065), Expect = e-116
Identities = 236/472 (50%), Positives = 306/472 (64%), Gaps = 5/472 (1%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 3 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
C A ++ V+DCPR +QPL VF+++ LK +++DE L++ WV+ R+ +HL
Sbjct: 123 AHGCFLNAKRNKKPVQDCPRMRGRQPLTVFVELWLKNRTLDEYLTYLLLWVKQRKDLLHL 182
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL M+NL+KL +
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 241
Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
S D Y+ S E + ++V +F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+
Sbjct: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 300
Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
DCGI S++ ILPALSRC L TF F GN M L++LL HT L NL +E YPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
S G + ++AELM +R++R P RI F CP CG LE
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
>gi|61696142 PRAME family member 5 [Homo sapiens]
Length = 476
Score = 413 bits (1061), Expect = e-115
Identities = 237/476 (49%), Positives = 308/476 (64%), Gaps = 5/476 (1%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q V PRRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
C A ++ V+DCPR +QPL VF+++ LK +++DE L+ WV+ R+ +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL M+NL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
S D Y+ S E + ++V +F++ FL+L LQ L M + F EG+LDQL+ CLK+ L+
Sbjct: 240 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
DCGI S++ ILPALSRC L TF F GN SM L++LL HT L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
S D G + ++AELM+ +R++R P RI F CP CG LE + C
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
>gi|58219004 PRAME family member 6 [Homo sapiens]
Length = 476
Score = 412 bits (1060), Expect = e-115
Identities = 237/476 (49%), Positives = 307/476 (64%), Gaps = 5/476 (1%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q V PRRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
C A + V+DCPR +QPL VF+++ LK +++DE L+ WV+ R+ +HL
Sbjct: 121 ARGCFLNAKRNKTPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL M+NL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
S D Y+ S E + ++V +F++ FL+L LQ L M + F EG+LDQL+ CLK+ L+
Sbjct: 240 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
DCGI S++ ILPALSRC L TF F GN SM L++LL HT L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSRCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
S D G + ++AELM+ +R++R P RI F CP CG LE + C
Sbjct: 419 SYDADGTLCWSRFAQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
>gi|239741045 PREDICTED: PRAME family member 23 [Homo sapiens]
Length = 476
Score = 409 bits (1052), Expect = e-114
Identities = 236/476 (49%), Positives = 307/476 (64%), Gaps = 5/476 (1%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS + P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 1 MSIRTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 60
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q V PRRWKLQVL+++DV ENFW +WS A
Sbjct: 61 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVHPRRWKLQVLDLQDVCENFWMVWSEAM 120
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
C A ++ V+DCPR +QPL VF+++ LK +++DE L+ WV+ R+ +HL
Sbjct: 121 AHGCFLNAKRNKKPVQDCPRMRGQQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 180
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL M+NL+KL +
Sbjct: 181 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLVL 239
Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
S D Y+ S E + ++V +F++ FL+L LQ L M + F EG+LDQL+ CLK+ L+
Sbjct: 240 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLCCLQKLSMNSVSFLEGHLDQLLSCLKTSLKV 298
Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 299 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 358
Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
DCGI S++ ILPALS C L TF F GN SM L++LL HT L NL +E YPAPRE
Sbjct: 359 DCGIIDSQVNAILPALSCCFELNTFSFCGNPISMATLENLLSHTIILKNLCVELYPAPRE 418
Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLEFNFC 473
S D G + ++AELM+ +R++R P RI F CP CG LE + C
Sbjct: 419 SYDADGTLCWSRFPQIRAELMKRVRDLRHPKRILFCTDCCPDCGNRSFYDLEADQC 474
>gi|239741043 PREDICTED: PRAME family member 11 [Homo sapiens]
Length = 513
Score = 408 bits (1049), Expect = e-114
Identities = 232/461 (50%), Positives = 301/461 (65%), Gaps = 5/461 (1%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS + P RLLEL G+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQAWP
Sbjct: 38 MSIRIPPRLLELXGRSLLRDQALAVSTLEELPTELFPPLFMEAFSRRRCEALKLMVQAWP 97
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL Q VRPRRWKLQVL+++DV ENFW +WS A
Sbjct: 98 FRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKLQVLDLQDVCENFWMVWSEAM 157
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
C A + V+DCPR E+QPL VF+++ LK +++DE L+ WV+ RR +HL
Sbjct: 158 AHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTLDEYLTCLLLWVKQRRDLLHL 217
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL ++NL+KL +
Sbjct: 218 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILPILTQFTPYLGHLRNLQKLVL 276
Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
S D Y+ S E + ++V +F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+
Sbjct: 277 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKV 335
Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 336 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 395
Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
DCGI S++ ILPALSRC L TF F GN M L++LL HT L NL LE YPAP+E
Sbjct: 396 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCLELYPAPQE 455
Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCP 458
S G + ++AELM+ +R +R P RI F +CP
Sbjct: 456 SYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNCP 496
>gi|59958373 PRAME family member 4 [Homo sapiens]
Length = 478
Score = 407 bits (1047), Expect = e-114
Identities = 235/472 (49%), Positives = 303/472 (64%), Gaps = 5/472 (1%)
Query: 1 MSFQAPRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWP 60
MS P RLLELAG+SLLRDQALA+S L+ELP ELFP LF+EAF+ RRCE LK+MVQ+WP
Sbjct: 3 MSIWTPPRLLELAGRSLLRDQALAMSTLEELPTELFPPLFMEAFSRRRCEALKLMVQSWP 62
Query: 61 FPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKLQVLEMRDVDENFWTIWSGAR 120
F LPL L+K P LE V+DG+D LL VRPRRWKLQVL+++DV ENFW +WS A
Sbjct: 63 FRRLPLRPLIKMPCLEAFQAVLDGLDALLNLGVRPRRWKLQVLDLQDVCENFWMVWSEAM 122
Query: 121 PLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSVDEDLSFFSGWVQHRRRSVHL 180
C A ++ VEDCPR +QPL VF+++ LK +++DE L+ WV+ R+ +HL
Sbjct: 123 AHGCFLNAKRNKKPVEDCPRMRGRQPLTVFVELWLKNRTLDEYLTCLLLWVKQRKDLLHL 182
Query: 181 CCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC-MVAEVSRYLSQMKNLRKLFI 239
CC K+ M N R+IL+ V D IQ +E+ N W ++ + + YL M+NL+KL +
Sbjct: 183 CCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWVLPILTQFTPYLGHMRNLQKLIL 241
Query: 240 S--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCLKSPLET 297
S D Y+ S E + ++V +F++ FL+L LQ LYM + F EG+LDQL+ CLK+ L+
Sbjct: 242 SHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSVSFLEGHLDQLLSCLKTSLKF 300
Query: 298 LALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATLQTLFLV 357
L +T L E DLK L PS+SQLK L+LS L L PL+ LLEKVAATL+ L L
Sbjct: 301 LTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSLVPLQILLEKVAATLEYLDLD 360
Query: 358 DCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLETYPAPRE 417
DCGI S++ ILPALSRC L TF F GN M L++LL HT L NL +E YPAPRE
Sbjct: 361 DCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENLLSHTIILKNLCVELYPAPRE 420
Query: 418 SLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCGMSPTEQLE 469
S G + ++AELM +R++R P RI F CP CG LE
Sbjct: 421 SYGADGTLCWSRFAQIRAELMNRVRDLRHPKRILFCTDYCPDCGNRSFYDLE 472
>gi|226437621 PRAME family member 11 [Homo sapiens]
Length = 436
Score = 354 bits (909), Expect = 9e-98
Identities = 203/421 (48%), Positives = 268/421 (63%), Gaps = 5/421 (1%)
Query: 41 VEAFTSRRCEVLKVMVQAWPFPCLPLGSLMKTPDLEILHYVVDGIDCLLAQKVRPRRWKL 100
+EAF+ RRCE LK+MVQAWPF LPL L+K P LE V+DG+D LL Q VRPRRWKL
Sbjct: 1 MEAFSRRRCEALKLMVQAWPFRRLPLRPLIKMPCLEAFQAVLDGLDALLTQGVRPRRWKL 60
Query: 101 QVLEMRDVDENFWTIWSGARPLSCSPEAMSKRQTVEDCPRTGEKQPLKVFMDVCLKEKSV 160
QVL+++DV ENFW +WS A C A + V+DCPR E+QPL VF+++ LK +++
Sbjct: 61 QVLDLQDVCENFWMVWSEAMAHGCFLNAKRNKTPVQDCPRMRERQPLTVFVELWLKNRTL 120
Query: 161 DEDLSFFSGWVQHRRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPC- 219
DE L+ WV+ RR +HLCC K+ M N R+IL+ V D IQ +E+ N W
Sbjct: 121 DEYLTCLLLWVKQRRDLLHLCCKKLKILGMPFRNIRSILKMVNLDCIQEVEV-NCKWILP 179
Query: 220 MVAEVSRYLSQMKNLRKLFIS--DGCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRI 277
++ + + YL ++NL+KL +S D Y+ S E + ++V +F++ FL+L LQ LYM +
Sbjct: 180 ILTQFTPYLGHLRNLQKLVLSHMDVSRYV-SPEQKKEIVTQFTTQFLKLRCLQKLYMNSV 238
Query: 278 RFFEGYLDQLIRCLKSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRL 337
F EG+LDQL+ CLK+ L+ L +T L E DLK L PS+SQLK L+LS L L
Sbjct: 239 SFLEGHLDQLLSCLKTSLKVLTITNCVLLESDLKHLSQCPSISQLKTLDLSGIRLTNYSL 298
Query: 338 EPLRALLEKVAATLQTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDL 397
PL+ LLEKVAATL+ L L DCGI S++ ILPALSRC L TF F GN M L++L
Sbjct: 299 VPLQILLEKVAATLEYLDLDDCGIIDSQVNAILPALSRCFELNTFSFCGNPICMATLENL 358
Query: 398 LRHTGRLSNLSLETYPAPRESLDNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSC 457
L HT L NL LE YPAP+ES G + ++AELM+ +R +R P RI F +C
Sbjct: 359 LSHTIILKNLCLELYPAPQESYGADGTLCWSRFAQIRAELMKKVRHLRHPKRILFCTDNC 418
Query: 458 P 458
P
Sbjct: 419 P 419
>gi|46249373 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 349 bits (896), Expect = 3e-96
Identities = 214/471 (45%), Positives = 294/471 (62%), Gaps = 15/471 (3%)
Query: 5 APRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWPFPCL 64
+PRRL+ELAGQSLL+D+ALAI+ L+ LPRELFP LF+ AF R + LK MVQAWPF CL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLEMR-DVDENFWTIWSGARP 121
PLG LMK L E V+DG+D LLAQ+VRPRRWKLQVL++R + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKSVDEDLSFFSGWVQH 173
S PEA M+K++ V+ E+ P++V +D+ LKE + DE S+ V+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKN 233
++ + LCC K+ ++M + + + IL+ V DSI+ LE+ +A+ S YL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLFISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCL 291
LR+L +S Y+ S E + Q +A+F+S FL L+ LQ LY+ + F G LDQL+R +
Sbjct: 262 LRRLLLSHIHASSYI-SPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 KSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATL 351
+PLETL++T L E D+ L PS+SQL L+LS L + EPL+ALLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 QTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLET 411
Q L +CGI +L +LP+LS CS LTT F+GN S+ L+ LL+H LSNL+
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPRESL-DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCG 461
YP P ES D G + E L L A L +L E+ P+ ++ CP CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
>gi|46249371 preferentially expressed antigen in melanoma [Homo
sapiens]
Length = 509
Score = 349 bits (896), Expect = 3e-96
Identities = 214/471 (45%), Positives = 294/471 (62%), Gaps = 15/471 (3%)
Query: 5 APRRLLELAGQSLLRDQALAISVLDELPRELFPRLFVEAFTSRRCEVLKVMVQAWPFPCL 64
+PRRL+ELAGQSLL+D+ALAI+ L+ LPRELFP LF+ AF R + LK MVQAWPF CL
Sbjct: 22 SPRRLVELAGQSLLKDEALAIAALELLPRELFPPLFMAAFDGRHSQTLKAMVQAWPFTCL 81
Query: 65 PLGSLMKTPDL--EILHYVVDGIDCLLAQKVRPRRWKLQVLEMR-DVDENFWTIWSGARP 121
PLG LMK L E V+DG+D LLAQ+VRPRRWKLQVL++R + ++FWT+WSG R
Sbjct: 82 PLGVLMKGQHLHLETFKAVLDGLDVLLAQEVRPRRWKLQVLDLRKNSHQDFWTVWSGNRA 141
Query: 122 LSCS---PEA---MSKRQTVEDCPRTGEKQ--PLKVFMDVCLKEKSVDEDLSFFSGWVQH 173
S PEA M+K++ V+ E+ P++V +D+ LKE + DE S+ V+
Sbjct: 142 SLYSFPEPEAAQPMTKKRKVDGLSTEAEQPFIPVEVLVDLFLKEGACDELFSYLIEKVKR 201
Query: 174 RRRSVHLCCTKVVNYSMNILNFRNILETVYPDSIQVLEIWNMCWPCMVAEVSRYLSQMKN 233
++ + LCC K+ ++M + + + IL+ V DSI+ LE+ +A+ S YL QM N
Sbjct: 202 KKNVLRLCCKKLKIFAMPMQDIKMILKMVQLDSIEDLEVTCTWKLPTLAKFSPYLGQMIN 261
Query: 234 LRKLFISD--GCGYLPSFESQGQLVAEFSSVFLRLEYLQMLYMRRIRFFEGYLDQLIRCL 291
LR+L +S Y+ S E + Q +A+F+S FL L+ LQ LY+ + F G LDQL+R +
Sbjct: 262 LRRLLLSHIHASSYI-SPEKEEQYIAQFTSQFLSLQCLQALYVDSLFFLRGRLDQLLRHV 320
Query: 292 KSPLETLALTYGSLDEEDLKCLPWYPSLSQLKQLNLSHGTLRFIRLEPLRALLEKVAATL 351
+PLETL++T L E D+ L PS+SQL L+LS L + EPL+ALLE+ +ATL
Sbjct: 321 MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQALLERASATL 380
Query: 352 QTLFLVDCGIGYSKLRVILPALSRCSNLTTFCFHGNDTSMDGLKDLLRHTGRLSNLSLET 411
Q L +CGI +L +LP+LS CS LTT F+GN S+ L+ LL+H LSNL+
Sbjct: 381 QDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISISALQSLLQHLIGLSNLTHVL 440
Query: 412 YPAPRESL-DNRGRVISELLTPLQAELMRILREVREPNRIFFGPVSCPCCG 461
YP P ES D G + E L L A L +L E+ P+ ++ CP CG
Sbjct: 441 YPVPLESYEDIHGTLHLERLAYLHARLRELLCELGRPSMVWLSANPCPHCG 491
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.438
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,072,419
Number of Sequences: 37866
Number of extensions: 780379
Number of successful extensions: 2486
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2352
Number of HSP's gapped (non-prelim): 64
length of query: 479
length of database: 18,247,518
effective HSP length: 106
effective length of query: 373
effective length of database: 14,233,722
effective search space: 5309178306
effective search space used: 5309178306
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.