BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens] (839 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens] 1691 0.0 gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens] 1553 0.0 gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo sapi... 340 2e-93 gi|170932524 nuclear receptor coactivator 7 isoform 1 [Homo sapi... 340 2e-93 gi|62909985 hypothetical protein LOC140711 [Homo sapiens] 205 1e-52 gi|205360930 hypothetical protein LOC57707 [Homo sapiens] 78 3e-14 gi|89886453 TBC1 domain family, member 24 [Homo sapiens] 77 9e-14 gi|116805342 human immunodeficiency virus type I enhancer bindin... 45 3e-04 gi|93204867 G protein-coupled receptor 158 [Homo sapiens] 45 4e-04 gi|56676335 RAP1 interacting factor 1 [Homo sapiens] 44 8e-04 gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 43 0.001 gi|60097902 filaggrin [Homo sapiens] 43 0.001 gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 41 0.004 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 41 0.005 gi|62244004 modulator of estrogen induced transcription isoform ... 40 0.007 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 40 0.009 gi|87299628 biorientation of chromosomes in cell division 1-like... 40 0.009 gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 40 0.012 gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 40 0.012 gi|71061468 centromere protein E [Homo sapiens] 40 0.012 gi|117414154 sodium channel associated protein 2 isoform b [Homo... 39 0.015 gi|117414162 sodium channel associated protein 2 isoform a [Homo... 39 0.015 gi|217330641 IWS1 homolog [Homo sapiens] 39 0.020 gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 39 0.020 gi|119226220 membrane-spanning 4-domains, subfamily A, member 14... 39 0.020 gi|119226217 membrane-spanning 4-domains, subfamily A, member 14... 39 0.020 gi|24415404 MDN1, midasin homolog [Homo sapiens] 39 0.020 gi|189217876 sal-like 1 isoform b [Homo sapiens] 39 0.026 gi|118442837 sal-like 1 isoform a [Homo sapiens] 39 0.026 gi|8922940 gamma-taxilin [Homo sapiens] 39 0.026 >gi|194306543 oxidation resistance 1 isoform 2 [Homo sapiens] Length = 839 Score = 1691 bits (4379), Expect = 0.0 Identities = 839/839 (100%), Positives = 839/839 (100%) Query: 1 MDYLTTFTEKSGRLLRGTANRLLGFGGGGEARQVRFEDYLREPAQGDLGCGSPPHRPPAP 60 MDYLTTFTEKSGRLLRGTANRLLGFGGGGEARQVRFEDYLREPAQGDLGCGSPPHRPPAP Sbjct: 1 MDYLTTFTEKSGRLLRGTANRLLGFGGGGEARQVRFEDYLREPAQGDLGCGSPPHRPPAP 60 Query: 61 SSPEGPDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNK 120 SSPEGPDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNK Sbjct: 61 SSPEGPDTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNK 120 Query: 121 LFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPS 180 LFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPS Sbjct: 121 LFSRAVVTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPS 180 Query: 181 STFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKND 240 STFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKND Sbjct: 181 STFTGIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKND 240 Query: 241 PLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSN 300 PLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSN Sbjct: 241 PLVQENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSN 300 Query: 301 TEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASS 360 TEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASS Sbjct: 301 TEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASS 360 Query: 361 ESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIA 420 ESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIA Sbjct: 361 ESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIA 420 Query: 421 DNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQ 480 DNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQ Sbjct: 421 DNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQ 480 Query: 481 GKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLK 540 GKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLK Sbjct: 481 GKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLK 540 Query: 541 EKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFI 600 EKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFI Sbjct: 541 EKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFI 600 Query: 601 QWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDINSKQVATV 660 QWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDINSKQVATV Sbjct: 601 QWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDINSKQVATV 660 Query: 661 KADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRT 720 KADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRT Sbjct: 661 KADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRT 720 Query: 721 MTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMF 780 MTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMF Sbjct: 721 MTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMF 780 Query: 781 FIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE 839 FIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE Sbjct: 781 FIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE 839 >gi|194306541 oxidation resistance 1 isoform 1 [Homo sapiens] Length = 846 Score = 1553 bits (4020), Expect = 0.0 Identities = 773/773 (100%), Positives = 773/773 (100%) Query: 67 DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV 126 DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV Sbjct: 74 DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV 133 Query: 127 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGI 186 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGI Sbjct: 134 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGI 193 Query: 187 RPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQEN 246 RPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQEN Sbjct: 194 RPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQEN 253 Query: 247 GCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDS 306 GCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDS Sbjct: 254 GCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDS 313 Query: 307 RIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTV 366 RIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTV Sbjct: 314 RIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTV 373 Query: 367 NQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGI 426 NQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGI Sbjct: 374 NQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGI 433 Query: 427 SGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQ 486 SGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQ Sbjct: 434 SGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQ 493 Query: 487 DSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHR 546 DSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHR Sbjct: 494 DSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHR 553 Query: 547 LHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEI 606 LHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEI Sbjct: 554 LHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERTDHLYAFFIQWSPEI 613 Query: 607 YAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDINSKQVATVKADLES 666 YAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDINSKQVATVKADLES Sbjct: 614 YAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDINSKQVATVKADLES 673 Query: 667 ESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDT 726 ESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDT Sbjct: 674 ESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDT 733 Query: 727 PVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDM 786 PVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDM Sbjct: 734 PVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVFKWTGDNMFFIKGDM 793 Query: 787 DSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE 839 DSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE Sbjct: 794 DSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQDIEIWAFE 846 >gi|170932526 nuclear receptor coactivator 7 isoform 2 [Homo sapiens] Length = 931 Score = 340 bits (873), Expect = 2e-93 Identities = 163/307 (53%), Positives = 210/307 (68%), Gaps = 5/307 (1%) Query: 533 IESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERT 592 IE KE++ FLC++VGKPMRK+F + +A +QQY +R K+ EYWFAVP+ER Sbjct: 630 IEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERV 689 Query: 593 DHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDI 652 DHLY FF+QWSP++Y +D +E GF+VV+K EE I++ ++ + WEI T E+ Sbjct: 690 DHLYTFFVQWSPDVYGKDA----KEQGFVVVEK-EELNMIDNFFSEPTTKSWEIITVEEA 744 Query: 653 NSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGT 712 ++ + E E P L S LL IE+L + LP R GYPW L Y T +HGT Sbjct: 745 KRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGT 804 Query: 713 SLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVF 772 SLKTLYR LD+PVL+VIKD D Q+FGA A+ P K SD +YGTGETF++TF P F+VF Sbjct: 805 SLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVF 864 Query: 773 KWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQD 832 KW+G+N +FI GD+ SL GGGGG F LWLD DLYHGRS+SC TF N LSKKEDF +QD Sbjct: 865 KWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQD 924 Query: 833 IEIWAFE 839 +E+WAF+ Sbjct: 925 LEVWAFD 931 Score = 237 bits (605), Expect = 3e-62 Identities = 152/353 (43%), Positives = 199/353 (56%), Gaps = 33/353 (9%) Query: 67 DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV 126 D Q KT DKK+ ++M QKP GT+EYT ++D+LNSIALKF+ TPN+LV+LNKLF+ + Sbjct: 91 DDNQNKTHDKKE-KKMVVQKPHGTMEYTAGNQDTLNSIALKFNITPNKLVELNKLFTHTI 149 Query: 127 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGI 186 V GQVL+VPD SS S SP + +SP+SS+AE+DK + D+ P Sbjct: 150 VPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIE----- 204 Query: 187 RPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQEN 246 RV+SSTSEE+E KFLK+NC+Y T GKG V GV++VTPNNIMFDPHK+DPLV EN Sbjct: 205 ---RVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIEN 261 Query: 247 GCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPID---IDQLSGRDFCHSKKMTGSNTEE 303 GCEEYG++CPMEEV+S A+Y +I KIK++LP D S +D K N E+ Sbjct: 262 GCEEYGLICPMEEVVSIALYNDISHMKIKDALPSPGEWEDLASEKDINPFSKFKSINKEK 321 Query: 304 IDSRIRDAGNDSASTA---PRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASS 360 R + T+ P E + T+ S + E+L D SS +S Sbjct: 322 -----RQQNGEKIMTSDSRPIVPLEKSTGHTPTKPSGSSVSEKLKKLD------SSRETS 370 Query: 361 ESVQTVNQAEVESLTVKS--ESTGTPGHLRS-----DTEHSTNEVGTLCHKTD 406 TV + E S EST L D E +++ G HK D Sbjct: 371 HGSPTVTKLSKEPSDTSSAFESTAKENFLGEDDDFVDLEELSSQTGGGMHKKD 423 >gi|170932524 nuclear receptor coactivator 7 isoform 1 [Homo sapiens] Length = 942 Score = 340 bits (873), Expect = 2e-93 Identities = 163/307 (53%), Positives = 210/307 (68%), Gaps = 5/307 (1%) Query: 533 IESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHEYWFAVPQERT 592 IE KE++ FLC++VGKPMRK+F + +A +QQY +R K+ EYWFAVP+ER Sbjct: 641 IEDILPSKEEKSKTPPMFLCIKVGKPMRKSFATHTAAMVQQYGKRRKQPEYWFAVPRERV 700 Query: 593 DHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDI 652 DHLY FF+QWSP++Y +D +E GF+VV+K EE I++ ++ + WEI T E+ Sbjct: 701 DHLYTFFVQWSPDVYGKDA----KEQGFVVVEK-EELNMIDNFFSEPTTKSWEIITVEEA 755 Query: 653 NSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGKHGT 712 ++ + E E P L S LL IE+L + LP R GYPW L Y T +HGT Sbjct: 756 KRRKSTCSYYEDEDEEVLPVLRPHSALLENMHIEQLARRLPARVQGYPWRLAYSTLEHGT 815 Query: 713 SLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEFEVF 772 SLKTLYR LD+PVL+VIKD D Q+FGA A+ P K SD +YGTGETF++TF P F+VF Sbjct: 816 SLKTLYRKSASLDSPVLLVIKDMDNQIFGAYATHPFKFSDHYYGTGETFLYTFSPHFKVF 875 Query: 773 KWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFFIQD 832 KW+G+N +FI GD+ SL GGGGG F LWLD DLYHGRS+SC TF N LSKKEDF +QD Sbjct: 876 KWSGENSYFINGDISSLELGGGGGRFGLWLDADLYHGRSNSCSTFNNDILSKKEDFIVQD 935 Query: 833 IEIWAFE 839 +E+WAF+ Sbjct: 936 LEVWAFD 942 Score = 238 bits (608), Expect = 1e-62 Identities = 122/218 (55%), Positives = 157/218 (72%), Gaps = 9/218 (4%) Query: 67 DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV 126 D Q KT DKK+ ++M QKP GT+EYT ++D+LNSIALKF+ TPN+LV+LNKLF+ + Sbjct: 91 DDNQNKTHDKKE-KKMVVQKPHGTMEYTAGNQDTLNSIALKFNITPNKLVELNKLFTHTI 149 Query: 127 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGI 186 V GQVL+VPD SS S SP + +SP+SS+AE+DK + D+ P Sbjct: 150 VPGQVLFVPDANSPSSTLRLSSSSPGATVSPSSSDAEYDKLPDADLARKALKPIE----- 204 Query: 187 RPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQEN 246 RV+SSTSEE+E KFLK+NC+Y T GKG V GV++VTPNNIMFDPHK+DPLV EN Sbjct: 205 ---RVLSSTSEEDEPGVVKFLKMNCRYFTDGKGVVGGVMIVTPNNIMFDPHKSDPLVIEN 261 Query: 247 GCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQ 284 GCEEYG++CPMEEV+S A+Y +I KIK++LP D+ Q Sbjct: 262 GCEEYGLICPMEEVVSIALYNDISHMKIKDALPSDLPQ 299 >gi|62909985 hypothetical protein LOC140711 [Homo sapiens] Length = 215 Score = 205 bits (522), Expect = 1e-52 Identities = 91/187 (48%), Positives = 128/187 (68%) Query: 650 EDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYPWTLVYGTGK 709 E+ ++ A A + P L++ S++L +I +L+ H PPR G+PW+LV+ T + Sbjct: 26 EEEEEEEAAPDPAAAPEDPTVPQLTEASQVLSASEIRQLSFHFPPRVTGHPWSLVFCTSR 85 Query: 710 HGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDGFYGTGETFVFTFCPEF 769 G SL++LYR M G PVL+V++D DGQ+FGA +S +++S GFYGTGETF+F+F P+ Sbjct: 86 DGFSLQSLYRRMEGCSGPVLLVLRDQDGQIFGAFSSSAIRLSKGFYGTGETFLFSFSPQL 145 Query: 770 EVFKWTGDNMFFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTLSKKEDFF 829 +VFKWTG N FF+KGD+DSL G G G F LWLDGDL+ G S C TF N L+++E F Sbjct: 146 KVFKWTGSNSFFVKGDLDSLMMGSGSGRFGLWLDGDLFRGGSSPCPTFNNEVLARQEQFC 205 Query: 830 IQDIEIW 836 IQ++E W Sbjct: 206 IQELEAW 212 >gi|205360930 hypothetical protein LOC57707 [Homo sapiens] Length = 456 Score = 78.2 bits (191), Expect = 3e-14 Identities = 50/153 (32%), Positives = 72/153 (47%), Gaps = 10/153 (6%) Query: 694 PRTIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSDG 753 PR + W L++ + HG S L +T P + V++D D VFG AS +V Sbjct: 259 PREQRHRWCLLFSSELHGHSFSQLCGHITHRG-PCVAVLEDHDKHVFGGFASCSWEVKPQ 317 Query: 754 FYGTGETFVFTFCPEFEVFKWTGDN---MFFIKGDM---DSLAFGGGGGEFALWLDGDLY 807 F G F+F+ CP V+ TG N M+ G + L GG F LW+D D Sbjct: 318 FQGDNRCFLFSICPSMAVYTHTGYNDHYMYLNHGQQTIPNGLGMGGQHNYFGLWVDVDFG 377 Query: 808 HGRSH---SCKTFGNRTLSKKEDFFIQDIEIWA 837 G S +C T+ + LS +E+F +E+WA Sbjct: 378 KGHSRAKPTCTTYNSPQLSAQENFQFDKMEVWA 410 >gi|89886453 TBC1 domain family, member 24 [Homo sapiens] Length = 553 Score = 76.6 bits (187), Expect = 9e-14 Identities = 68/257 (26%), Positives = 108/257 (42%), Gaps = 67/257 (26%) Query: 636 SNQAAAREWEITTREDINSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPR 695 +N+ A ++ IT ++ +A + +E+FR SE++ ++ + +P R Sbjct: 306 ANEKALKQKGITVKQKRQFVHLA-----VHAENFR------SEIVSVREMRDIWSWVPER 354 Query: 696 TIGYPWTLVYGTGKHGTSLKTLYRTMTGLDTPVLMVIKDSDGQVFGALASEPLKVSD--- 752 L++ + +HG SL Y G + P L++IK + +V GA S + Sbjct: 355 FALCQPLLLFSSLQHGYSLARFYFQCEGHE-PTLLLIKTTQKEVCGAYLSTDWSERNKFG 413 Query: 753 ---GFYGTGETFVFTFCPEFEVFKWT------------------------------GDNM 779 GF+GTGE FVF PE + ++W D + Sbjct: 414 GKLGFFGTGECFVFRLQPEVQRYEWVVIKHPELTKPPPLMAAEPTAPLSHSASSDPADRL 473 Query: 780 -----------------FFIKGDMDSLAFGGGGGEFALWLDGDLYHGRSHSCKTFGNRTL 822 F+ G D L GGGGG+ AL++DGDL GR+ C TF N+ L Sbjct: 474 SPFLAARHFNLPSKTESMFMAGGSDCLIVGGGGGQ-ALYIDGDLNRGRTSHCDTFNNQPL 532 Query: 823 SKKEDFFIQDIEIWAFE 839 E+F I +E W F+ Sbjct: 533 C-SENFLIAAVEAWGFQ 548 >gi|116805342 human immunodeficiency virus type I enhancer binding protein 1 [Homo sapiens] Length = 2718 Score = 45.1 bits (105), Expect = 3e-04 Identities = 82/373 (21%), Positives = 145/373 (38%), Gaps = 53/373 (14%) Query: 47 DLGCGSPPHRPPA-----PSSPEGPD-TGQKKTLDKKDG---RRMSFQKPKGTIEYTVES 97 D G +PP P PSSP TG L+++ G R++S + V Sbjct: 1389 DCGSITPPQTTPLTELQPPSSPSRVGVTGHVPLLERRRGPLVRQISLNIAPDSHLSPVHP 1448 Query: 98 RDSLNSIALKFDTTPNELVQLNKLFSRAVVTGQVLY----VPDPEYVSSVESSPSLSPVS 153 N+ + P + QL S A + L+ V D + +S SS ++ PV Sbjct: 1449 TSFQNTALPSVNAVPYQGPQLTST-SLAEFSANTLHSQTQVKDLQAETSNSSSTNVFPVQ 1507 Query: 154 PLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGIRPAR--VVSSTSEEEEAFTEKFLKINC 211 L + + P T+ + + G +P + V+S +S+ E+ F K+ +++C Sbjct: 1508 QLCDINLLNQIHAP--PSHQSTQLSLQVSTQGSKPDKNSVLSGSSKSEDCFAPKY-QLHC 1564 Query: 212 KYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQ---------ENGCEEYGIMCP------ 256 + TSG S + PN ++ DP D V ++ + ++ P Sbjct: 1565 QVFTSGPSCSSNPVHSLPNQVISDPVGTDHCVTSATLPTKLIDSMSNSHPLLPPELRPLG 1624 Query: 257 --MEEVMSAAMYKEILDSKIK-------ESLP--IDIDQLSGRDFCHSKKMTGSNTEEID 305 +++V S+ M L S + SLP + L + C + +EE + Sbjct: 1625 SQVQKVPSSFMLPIRLQSSVPAYCFATLTSLPQILVTQDLPNQPICQTNHSVVPISEEQN 1684 Query: 306 SRIRDAGNDSASTAPRSTEESLSEDVFTE-------SELSPIREELVSSDELRQDKSSGA 358 S + + P +E L E+VF+E SE PI +++ Q +SS + Sbjct: 1685 S-VPTLQKGHQNALPNPEKEFLCENVFSEMSQNSSLSESLPITQKISVGRLSPQQESSAS 1743 Query: 359 SSESVQTVNQAEV 371 S + N ++ Sbjct: 1744 SKRMLSPANSLDI 1756 >gi|93204867 G protein-coupled receptor 158 [Homo sapiens] Length = 1215 Score = 44.7 bits (104), Expect = 4e-04 Identities = 50/212 (23%), Positives = 83/212 (39%), Gaps = 23/212 (10%) Query: 308 IRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVN 367 IR +S+ +S EE+L VF+ + + + D+ + S S+ +T Sbjct: 788 IRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHV--RDQTEESSSLPTESQEEETTE 845 Query: 368 QAEVESLTVKSESTGTPGHLRSDTE-HSTNEVGTLCHKTDLNNLEMAIKE-----DQIAD 421 + +ESL+ K + L+ D+E ST V +C +NL K + Sbjct: 846 NSTLESLSGKKLTQ----KLKEDSEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQK 901 Query: 422 NFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQG 481 + I+ KE + + G + EE K P + E + S + + Sbjct: 902 SLSVIASAKEKTLGLAGKTQTAGV--------EERTKSQKPLPKDKETNRNHSNSDNTET 953 Query: 482 KEQNQDSQTEAEELRKLWKTHTMQQTKQQREN 513 K+ + AEE RK K+ M KQQR N Sbjct: 954 KDPAPQNSNPAEEPRKPQKSGIM---KQQRVN 982 >gi|56676335 RAP1 interacting factor 1 [Homo sapiens] Length = 2472 Score = 43.5 bits (101), Expect = 8e-04 Identities = 50/237 (21%), Positives = 102/237 (43%), Gaps = 28/237 (11%) Query: 295 KMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVF---------TESELSPIREELV 345 K+T SN E+ + + GN+++ T+ +SE+ +E++ + + + V Sbjct: 1905 KVTESNLEKAKTMELNVGNEASFHGQERTKTGISEEAAIEENKRNDDSEADTAKLNAKEV 1964 Query: 346 SSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKT 405 +++E D S ++ V+ Q E+ T E G G+ SD HS+ E T Sbjct: 1965 ATEEFNSDISLSDNTTPVKLNAQTEISEQTAAGELDG--GNDVSDL-HSSEETNTKMK-- 2019 Query: 406 DLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGE 465 NN EM I E G T +G + + S E + ++ +N C + Sbjct: 2020 --NNEEMMIGEAMAETGHDG-------ETENEGITTKTSKPDEAETNMLTAEMDNFVC-D 2069 Query: 466 TAEFKQKQSV---NKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQ 519 T E ++ + NK + E ++ S+ + + + + ++ +Q+ + +++ SQ Sbjct: 2070 TVEMSTEEGIIDANKTETNTEYSK-SEEKLDNNQMVMESDILQEDHHTSQKVEEPSQ 2125 >gi|124249396 coiled-coil domain containing 30 [Homo sapiens] Length = 783 Score = 43.1 bits (100), Expect = 0.001 Identities = 92/435 (21%), Positives = 161/435 (37%), Gaps = 76/435 (17%) Query: 198 EEEAFTEKFLKINCKYITSGKGTVSGVL----LVTPNNIMFDPHKNDPLVQ---ENGCEE 250 E K LK++ ++ T+ G L+T N DP N+P+++ ++ EE Sbjct: 78 ENSELETKVLKLSQEFAQLNHFTLGGKTAPSNLITSENTCKDPESNEPILETEIQSRKEE 137 Query: 251 YGIMCPMEEVMSAAMYKEILDSKIKE-SLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIR 309 +CP + KEI + +KE S P + EE + R Sbjct: 138 TEELCPK---LGERKQKEIPEESVKEGSFPRE-----------------GQKEEGSQQNR 177 Query: 310 DAGNDSASTAPRSTEESLSEDVFTESELSPIREELVS-SDELRQDKSSGASSESVQTVNQ 368 D EE + E+ +REEL + L Q +SSG SS+ + Sbjct: 178 D----------MKDEEKEQQLTMKPEEIVRLREELSHINQSLLQSQSSGDSSDDSGAQHP 227 Query: 369 AEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISG 428 + E L + H + + + LC+ + E+ + Q D Q S Sbjct: 228 SSGEKLKYNQQGEVQQLH------QNLHRLQILCNSAE---NELRYERGQNLDLKQHNSL 278 Query: 429 PKEDSTSIK-----------GNSDQDSFLHENSLHQEESQKE----------NMPCGETA 467 +E++ IK ++ S L H ++ KE ++ Sbjct: 279 LQEENIKIKIELKHAQQKLLDSTKMCSSLTAEYKHCQQKIKELELEVLKHTQSIKSQNNL 338 Query: 468 EFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQ-RENIQQVSQKEAKHKI 526 + K Q +K +E+ D Q + E K+ T T KQQ E I++ +Q EAK K Sbjct: 339 QEKLVQEKSKVADAEEKILDLQRKLEHAHKVCLTDTCISEKQQLEEKIKEATQNEAKVKQ 398 Query: 527 TSADGHIESSALLKE-KQRHRLHKFL-----CLRVGKPMRKTFVSQASATMQQYAQRDKK 580 + + L + + HR + L L + +++ + Q A ++Q +K Sbjct: 399 QYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENEKRK 458 Query: 581 HEYWFAVPQERTDHL 595 ++ QE ++ L Sbjct: 459 YDEHVKSNQELSEKL 473 >gi|60097902 filaggrin [Homo sapiens] Length = 4061 Score = 43.1 bits (100), Expect = 0.001 Identities = 66/299 (22%), Positives = 114/299 (38%), Gaps = 49/299 (16%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 347 S + +G + S +RD+G+ +S + S E SED T+S + P ++ S Sbjct: 3636 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQ---SH 3692 Query: 348 DELRQDKSSGASSES------VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNE 397 E + +S+G S S V T Q+E + G G R + HS ++ Sbjct: 3693 QESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQ 3752 Query: 398 VG---TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ------------ 442 G H +Q D G SG T+ +G SD Sbjct: 3753 EGQDTIRGHPGSRRGGRQGSYHEQSVDR-SGHSGSHHSHTTSQGRSDASHGQSGSRSASR 3811 Query: 443 ---------DSFLHENSLHQEES-QKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEA 492 D H S H E S Q ++ ++ + + S +QG +QDS +EA Sbjct: 3812 ETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEA 3871 Query: 493 --EELRKLWKTHTMQQTKQQRENIQQVSQKE-AKHKITSADGHIESSALLKEKQRHRLH 548 E+ + ++ + RE + S+ + H+ T++ H++SS + + + H Sbjct: 3872 YPEDSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTAS--HVQSSPVQSDSSTAKEH 3928 Score = 42.0 bits (97), Expect = 0.002 Identities = 58/272 (21%), Positives = 94/272 (34%), Gaps = 25/272 (9%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 347 S + +G + S +RD+G+ +S + S E SED T+S + P ++ S Sbjct: 2340 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 2399 Query: 348 DELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG-------HLRSDTEHSTNEVGT 400 R SG S + V+ E T T G R + HST++ G Sbjct: 2400 TRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQ 2459 Query: 401 LC---HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQ 457 H + +Q+ D G SG T+ +G SD S H S Sbjct: 2460 DTIHGHPGSSSGGRQGSHYEQLVDR-SGHSGSHHSHTTSQGRSDA-SHGHSGSRSASRQT 2517 Query: 458 KENMPCGETAEFK----QKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQREN 513 + + G+ + + S G Q Q+E + W + Q + Q + Sbjct: 2518 RNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHS 2577 Query: 514 IQQVSQKEAKHKITSADGHIESSALLKEKQRH 545 E S + H + L++ RH Sbjct: 2578 ----EDSERWSGSASRNHHGSAQEQLRDGSRH 2605 Score = 41.2 bits (95), Expect = 0.004 Identities = 55/278 (19%), Positives = 97/278 (34%), Gaps = 47/278 (16%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 347 S + +G + S +RD+G+ +S + + E SED T+S + P ++ S Sbjct: 1367 SSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKES 1426 Query: 348 DELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG-------HLRSDTEHSTNEVG- 399 + +SSG S + V+ E T + T G R+ + HS ++ G Sbjct: 1427 ARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQ 1486 Query: 400 --TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ--------------- 442 H +Q D G SG T+ +G SD Sbjct: 1487 DTIRGHPGSSRGGRQGSYHEQSVDR-SGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTR 1545 Query: 443 ------DSFLHENSLHQEESQK----------ENMPCGETAEFKQKQSVNKGKQGKEQNQ 486 D H S H E S + + G +Q SV++ + + ++ Sbjct: 1546 NEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSE 1605 Query: 487 DSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKH 524 DS+ +E + +Q++ N + + A H Sbjct: 1606 DSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASH 1643 Score = 37.0 bits (84), Expect = 0.076 Identities = 58/272 (21%), Positives = 99/272 (36%), Gaps = 46/272 (16%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 352 S + +G + S +RD+G+ S + S E SED T+S + + S + Q Sbjct: 2988 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA--HGQAGSHQQSHQ 3045 Query: 353 DKSSGASSES----------VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNEV 398 + + G S E+ V T Q+E + G G + + HS ++ Sbjct: 3046 ESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQY 3105 Query: 399 G---TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ------------- 442 G H + D+ G SG T+ +G SD Sbjct: 3106 GQDTIRGHPGSSRGGRQGYHHEHSVDS-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRT 3164 Query: 443 --------DSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKG-KQGKEQNQDSQTEA- 492 DS H S H E S ++ A Q + + +QG +QDS +E Sbjct: 3165 TRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGH 3224 Query: 493 EELRKLWKTHTMQQTKQQRENIQQVSQKEAKH 524 E + W + ++ R ++Q+ S+ ++H Sbjct: 3225 SEDSERW---SGSASRNHRGSVQEQSRHGSRH 3253 Score = 36.6 bits (83), Expect = 0.100 Identities = 55/270 (20%), Positives = 96/270 (35%), Gaps = 42/270 (15%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESEL--SPIREELVSSDEL 350 S + +G+ + S +RD+G+ +S + + E SED T+S S E Sbjct: 719 SSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQES 778 Query: 351 RQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG----------HLRSDTEHSTNEVG- 399 +D+S S S + Q + S P R ++ HS ++ G Sbjct: 779 ARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQ 838 Query: 400 --TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD---------------- 441 H +Q D G SG T+ +G SD Sbjct: 839 DTIRGHPGSSRRGRQGSHHEQSVDR-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 897 Query: 442 -----QDSFLHENSLHQEESQKENMP-CGETAEFKQKQSVNKGKQGKEQNQDSQTEA-EE 494 +D H S H E S ++ + + + + S +QG +QDS +E E Sbjct: 898 NEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSE 957 Query: 495 LRKLWKTHTMQQTKQQRENIQQVSQKEAKH 524 + W + ++ R + Q+ S+ ++H Sbjct: 958 DSERW---SGSASRNHRGSAQEQSRHGSRH 984 Score = 34.3 bits (77), Expect = 0.49 Identities = 61/285 (21%), Positives = 101/285 (35%), Gaps = 41/285 (14%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE--ELVSSDEL 350 S + +G + S +RD+G+ +S + S E SE+ T+S ++ S E Sbjct: 1043 SSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQES 1102 Query: 351 RQDKSSGASSES------VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNEVG- 399 +D S G S S V T Q+E ++ + G R + HS ++ G Sbjct: 1103 ARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQ 1162 Query: 400 --TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ--------------- 442 H +Q D G SG T+ +G SD Sbjct: 1163 DTIRAHPGSRRGGRQGSHHEQSVDR-SGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTR 1221 Query: 443 ------DSFLHENSLHQE-ESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTE--AE 493 D H S H E S ++ + + + S QG +QDS +E ++ Sbjct: 1222 KDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSD 1281 Query: 494 ELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSAD-GHIESSA 537 + +L + + RE + S+ H+ A GH S+ Sbjct: 1282 DSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSS 1326 Score = 33.1 bits (74), Expect = 1.1 Identities = 38/164 (23%), Positives = 62/164 (37%), Gaps = 16/164 (9%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 347 S + +G + S +RD+G+ S + S E SED T+S + P ++ S Sbjct: 2016 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKES 2075 Query: 348 DELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG-------HLRSDTEHSTNEVG- 399 + +SSG S + V+ E T + T G + + HS ++ G Sbjct: 2076 ARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQ 2135 Query: 400 --TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD 441 H ++Q D G SG T+ +G SD Sbjct: 2136 DTIRGHPGPSRGGRQGSHQEQSVDR-SGHSGSHHSHTTSQGRSD 2178 Score = 32.7 bits (73), Expect = 1.4 Identities = 59/285 (20%), Positives = 101/285 (35%), Gaps = 45/285 (15%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 352 S + +G + S +RD+G+ S + S E SED T+S + + S + Q Sbjct: 2664 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSA--HGQAGSHQQSHQ 2721 Query: 353 DKSSGASSES----------VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNEV 398 + + G S E+ V T Q+E + G G + + HS ++ Sbjct: 2722 ESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQD 2781 Query: 399 G---TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ------------- 442 G H + D+ G SG T+ +G SD Sbjct: 2782 GQDTIRGHPGSSRGGRQGYHHEHSVDS-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRT 2840 Query: 443 --------DSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKG-KQGKEQNQDSQTE-- 491 D H S H E S ++ A Q + + +QG +QDS +E Sbjct: 2841 TRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGH 2900 Query: 492 AEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESS 536 +E+ + + + +E ++ S+ H+ A GH S+ Sbjct: 2901 SEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRA-GHGHSA 2944 Score = 31.6 bits (70), Expect = 3.2 Identities = 60/282 (21%), Positives = 101/282 (35%), Gaps = 50/282 (17%) Query: 305 DSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSES-- 362 DSR + AS + +EES ++ V + P ++ S E +D+S G S S Sbjct: 3329 DSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQ---SHQESARDRSGGRSGRSGS 3385 Query: 363 ----VQTVNQAEVESLTVKSESTGTPG----HLRSDTEHSTNEVG---TLCHKTDLNNLE 411 V T Q+E ++ + G R + HS ++ G H Sbjct: 3386 FLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGR 3445 Query: 412 MAIKEDQIADNFQGISGPKEDSTSIKGNSDQ---------------------DSFLHENS 450 +Q D G SG T+ +G SD D H S Sbjct: 3446 QGSHYEQSVDR-SGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWS 3504 Query: 451 LHQEES----QKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQ 506 H E S + G+ + S N+G Q+ DSQ +E+ + W + Sbjct: 3505 HHHEASTQADSSRHSQSGQGQSAGPRTSRNQG-SSVSQDSDSQGHSEDSER-W---SGSA 3559 Query: 507 TKQQRENIQQVSQKEAKHKITSAD---GHIESSALLKEKQRH 545 ++ R + Q+ S+ ++H + + GH S+ ++ H Sbjct: 3560 SRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTH 3601 Score = 30.4 bits (67), Expect = 7.1 Identities = 61/297 (20%), Positives = 103/297 (34%), Gaps = 50/297 (16%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSS 347 S + + + + S + D G+ +S + S E SE+ T+S + ++ S Sbjct: 394 SSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQES 453 Query: 348 DELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG-------HLRSDTEHSTNEVG- 399 R + SG S S+ V+ E T T G R + HS ++ G Sbjct: 454 TRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQ 513 Query: 400 -TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQ---------------- 442 T+ + + + N G SG T+ +G SD Sbjct: 514 DTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRN 573 Query: 443 -----DSFLHENSLHQEESQK----ENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAE 493 D H S H E S + + G+ + S N+G Q+ DSQ +E Sbjct: 574 EEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQG-SSVSQDSDSQGHSE 632 Query: 494 ELRKLW-----KTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRH 545 + + W + H +Q R+ + + H+ + GH S+ K RH Sbjct: 633 DSER-WSGSASRNHHGSAQEQSRDGSR---HPRSHHEDRAGHGHSADSS-RKSGTRH 684 Score = 30.0 bits (66), Expect = 9.3 Identities = 52/258 (20%), Positives = 93/258 (36%), Gaps = 39/258 (15%) Query: 297 TGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTES-----ELSPIREELVSSDELR 351 +G+ + S + D+GN +S + S E SE+ T+S + P ++ S + Sbjct: 1695 SGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQ 1754 Query: 352 QDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLE 411 + SG S + V+ E T G RS E + + ++ Sbjct: 1755 SGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARD-----------SSRH 1803 Query: 412 MAIKEDQIADNFQGISGPK---------EDSTSIKGNSDQDSFLHENSLHQEESQKENMP 462 A +E Q D +G G E S G+S H ++ QE S Sbjct: 1804 SASQEGQ--DTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSH---HSHTTSQERSDVSRGQ 1858 Query: 463 CGETAEFKQ----KQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVS 518 G + +Q KQS + + ++ ++ + A+ R H+ Q + Sbjct: 1859 SGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSR-----HSQVGQGQSSGPRTSRN 1913 Query: 519 QKEAKHKITSADGHIESS 536 Q + + + + GH E S Sbjct: 1914 QGSSVSQDSDSQGHSEDS 1931 >gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] Length = 727 Score = 41.2 bits (95), Expect = 0.004 Identities = 49/237 (20%), Positives = 94/237 (39%), Gaps = 32/237 (13%) Query: 355 SSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAI 414 SS AS E + NQ E + + +E EV ++ ++ E Sbjct: 118 SSSASREPYK--NQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVN 175 Query: 415 KEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQS 474 E+ +D+ G SG ++ +GN N+ ++EE +E++ E E ++ Sbjct: 176 SEEYGSDHETGSSGSSDE----QGN---------NTENEEEGVEEDVEEDEEVEEDAEED 222 Query: 475 VNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEA----KHKITSAD 530 + G+E+ ++ + E EE + + + + Q+ E ++ EA ++ D Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTD 282 Query: 531 GHIESSALL-----KEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHE 582 G + S + K+K+R R + F S+ + YA +KKHE Sbjct: 283 GSVRSGSGTDGSDEKKKERKRARGISPI--------VFDRSGSSASESYAGSEKKHE 331 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 40.8 bits (94), Expect = 0.005 Identities = 45/241 (18%), Positives = 102/241 (42%), Gaps = 30/241 (12%) Query: 314 DSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVES 373 D+ A +S++ + + + +++ V D+ ++D S ++ + + Sbjct: 287 DTKKNAKKSSDAESEDSKDAKKDSKKVKKN-VKKDDKKKDVKKDTESTDAESGDSKDERK 345 Query: 374 LTVKSESTGTPGHLRSDT----EHSTNEVGTLCH-KTDLNNLEMAIKEDQIADNFQGISG 428 T K + + DT E + E G + D NL+ A K D Sbjct: 346 DTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDD---------- 395 Query: 429 PKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDS 488 K+D+ I ++D E+ L +ESQK+ + ++ K+SV ++ + + + Sbjct: 396 KKKDAKKITFSTDS-----ESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEP 450 Query: 489 QTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLH 548 + ++++ +K + K ++++ + +K+AK S + +ES LK+ ++H Sbjct: 451 KGDSKKGKK-------DEKKGKKDSKKDDKKKDAKKNAESTE--MESDLELKKDKKHSKE 501 Query: 549 K 549 K Sbjct: 502 K 502 >gi|62244004 modulator of estrogen induced transcription isoform b [Homo sapiens] Length = 1016 Score = 40.4 bits (93), Expect = 0.007 Identities = 52/283 (18%), Positives = 116/283 (40%), Gaps = 50/283 (17%) Query: 295 KMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSE-DVFTESELSPIREELVSSDELRQD 353 +++G + E D+ I+D ++ + + L + + F E+E + + + S E + Sbjct: 91 ELSGDASVEDDAFIKDCELENQEAHEQDGNDELKDSEEFGENEEENVHSKELLSAEENKR 150 Query: 354 KSSGASSESVQTVNQAEVESLTVKSES-------TGTPGHLRSD-----------TEHST 395 +E ++ + + ++ES ++++ T G + T H Sbjct: 151 AHELIEAEGIEDIEKEDIESQEIEAQEGEDDTFLTAQDGEEEENEKEGSLAEADHTAHEE 210 Query: 396 NEVGTLCHKTDLNNLEMAIK-EDQIADNFQG----------------ISGPKEDSTSIKG 438 E T + + +N+ + I+ ED I +F G S PK+ +I Sbjct: 211 MEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKITDSEASKPKDGQDAIAQ 270 Query: 439 NSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQ-----DSQTEAE 493 + +++S +E + + ++ +KE+ G+ E + ++S K + G ++ S T A Sbjct: 271 SPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESGDKEKDTLKKGPSSTGAS 330 Query: 494 ELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESS 536 K +K+ +++ + S K+ K +S G SS Sbjct: 331 GQAK-------SSSKESKDS--KTSSKDDKGSTSSTSGSSGSS 364 Score = 37.4 bits (85), Expect = 0.058 Identities = 88/489 (17%), Positives = 185/489 (37%), Gaps = 73/489 (14%) Query: 67 DTGQKKTLDKKDGRRMSFQKPKGTIEYTVESRDSLNSIALKFDTTPNELVQLNKLFSRAV 126 D+ K D +D S +K E +D +K D E + +K Sbjct: 255 DSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEARESSKKAESG- 313 Query: 127 VTGQVLYVPDPEYVSSVESSPSLSPVSPLSPTSSEAEFDKTTNP--DVHPTEATPSSTFT 184 D E +++ PS + S + +SS+ D T+ D T +T S+ + Sbjct: 314 ---------DKEK-DTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGS 363 Query: 185 GIRPARVVSSTSEEEEAFTEKFLKINCKYITSGKGTVSGVLLVTPNNIMFDPHKNDPLVQ 244 + V +S + A + K + G V +VT + Sbjct: 364 STKNIWVSGLSSNTKAA--------DLKNLFGKYGKVLSAKVVTN-------------AR 402 Query: 245 ENGCEEYGIMCPMEEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEI 304 G + YGI+ + + +++ L I ++++ G K+M N E+ Sbjct: 403 SPGAKCYGIVTMSSSTEVSRCIAHLHRTELHGQL-ISVEKVKGDP--SKKEMKKENDEKS 459 Query: 305 DSRIRDAGNDSASTAPRS--TEESLSEDVFTESELSPIRE-----ELVSSDELRQDKSSG 357 SR + D +T+ RS T+ S+ ++ SE S +E ++ DE + +SG Sbjct: 460 SSR---SSGDKKNTSDRSSKTQASVKKEEKRSSEKSEKKESKDTKKIEGKDEKNDNGASG 516 Query: 358 ASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKED 417 +SES++ +S K S+ +PGH+ + +T ++ + + Sbjct: 517 QTSESIK-------KSEEKKRISSKSPGHM------------VILDQTKGDHCRPSRR-- 555 Query: 418 QIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNK 477 ++ I G ++ + +D + E KE F++ + + Sbjct: 556 ---GRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAME 612 Query: 478 GKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSA 537 ++ +E + + E E +R + + ++ +++RE ++ QK + ++ +E Sbjct: 613 LRRRREIAERERRERERIRIIREREERERLQRERERLEIERQKLERERMERE--RLERER 670 Query: 538 LLKEKQRHR 546 + E++R + Sbjct: 671 IRIEQERRK 679 Score = 33.1 bits (74), Expect = 1.1 Identities = 31/150 (20%), Positives = 66/150 (44%), Gaps = 5/150 (3%) Query: 403 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 462 H+T+L+ +++++ + + + + ++ +S + + D+ + +S Q +KE Sbjct: 428 HRTELHGQLISVEKVKGDPSKKEMKKENDEKSSSRSSGDKKNTSDRSSKTQASVKKEEKR 487 Query: 463 CGETAEFKQKQSVNK--GKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQK 520 E +E K+ + K GK K N S +E ++K + + + ++ + Q Sbjct: 488 SSEKSEKKESKDTKKIEGKDEKNDNGASGQTSESIKK--SEEKKRISSKSPGHMVILDQT 545 Query: 521 EAKHKITSADGHIES-SALLKEKQRHRLHK 549 + H S G E KEK+R L K Sbjct: 546 KGDHCRPSRRGRYEKIHGRSKEKERASLDK 575 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 40.0 bits (92), Expect = 0.009 Identities = 42/257 (16%), Positives = 85/257 (33%), Gaps = 4/257 (1%) Query: 281 DIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPI 340 D D + D +S + S+ S D+ + S S + ++ S S D S+ S Sbjct: 817 DSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNS 876 Query: 341 REELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGT 400 + SSD SS +S S N ++ +S + S + SD+ S+N Sbjct: 877 SDSSDSSDSNESSNSSDSSDSS----NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDN 932 Query: 401 LCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKEN 460 N+ + + D + S +S+ ++ DS NS +S + Sbjct: 933 SNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSS 992 Query: 461 MPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQK 520 + S + N + + + + + ++ Sbjct: 993 DSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1052 Query: 521 EAKHKITSADGHIESSA 537 ++ + S+D S + Sbjct: 1053 DSSNSSDSSDSSDSSDS 1069 Score = 38.9 bits (89), Expect = 0.020 Identities = 40/202 (19%), Positives = 77/202 (38%), Gaps = 8/202 (3%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSA-STAPRSTEESLSEDVFTESELSPIREELVSSDELR 351 S + S+ E DS D+ +DS+ S + S++ S S D S S + SSD Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSD--- 676 Query: 352 QDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLE 411 S +SS+S + + ++ + SES+ + SD+ S++ + +D +N Sbjct: 677 ----SSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSS 732 Query: 412 MAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQ 471 + +D+ +S +S S ++S + S N + Sbjct: 733 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSS 792 Query: 472 KQSVNKGKQGKEQNQDSQTEAE 493 S + + DS ++ Sbjct: 793 DSSDSSNSSDSSNSSDSSDSSD 814 Score = 38.1 bits (87), Expect = 0.034 Identities = 41/247 (16%), Positives = 92/247 (37%), Gaps = 6/247 (2%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSE--DVFTESELSPIREELVSSDEL 350 S S++ + DS ++ +DS S+ S++ S S+ D S+ S + SSD Sbjct: 558 SNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDS- 616 Query: 351 RQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNL 410 D S S S + ++ +S + S+S + SD+ S+N + ++ Sbjct: 617 -SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS 675 Query: 411 EMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFK 470 + + D + N S + S S + + DS ++S + S + + Sbjct: 676 DSSSSSD--SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733 Query: 471 QKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSAD 530 S N + + +++ + + + ++ + ++ S+D Sbjct: 734 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793 Query: 531 GHIESSA 537 S++ Sbjct: 794 SSDSSNS 800 Score = 38.1 bits (87), Expect = 0.034 Identities = 34/198 (17%), Positives = 73/198 (36%), Gaps = 4/198 (2%) Query: 299 SNTEEIDSRIRDAGNDS----ASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDK 354 S ++ DS D+ ++S +S + S++ S S D S S SSD Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN 697 Query: 355 SSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAI 414 SS +S S + + + S + S S+ + SD+ S+N + N+ + + Sbjct: 698 SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757 Query: 415 KEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQS 474 D + S DS+ +SD + + + + ++ ++++ Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817 Query: 475 VNKGKQGKEQNQDSQTEA 492 + N +++ Sbjct: 818 SDSSNSSDSSNSSDSSDS 835 Score = 36.6 bits (83), Expect = 0.100 Identities = 44/222 (19%), Positives = 76/222 (34%), Gaps = 5/222 (2%) Query: 272 SKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDV 331 S +S D S D S + S+ S D+ + S S + S ES S D Sbjct: 577 SSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636 Query: 332 FTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDT 391 ++S+ S SSD SS +S+ S + + +S S S + SD+ Sbjct: 637 DSKSDSSDSN----SSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDS 692 Query: 392 EHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSL 451 S+N +D ++ + + D N +S NS S ++S Sbjct: 693 SDSSNS-SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751 Query: 452 HQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAE 493 + S + + S + + DS ++ Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSD 793 Score = 36.6 bits (83), Expect = 0.100 Identities = 36/215 (16%), Positives = 84/215 (39%), Gaps = 7/215 (3%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSPIR 341 D + D S + S+ S D+ + S +S + S+ S S D S+ S Sbjct: 748 DSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSS 807 Query: 342 EELVSSDELRQDKSSGA----SSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTN- 396 + SSD D S+ + SS+S + N ++ + S+ + + RSD+ +S++ Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867 Query: 397 -EVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEE 455 + + +D ++ + + +D+ + DS+ +SD + + + Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESS 927 Query: 456 SQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQT 490 + +N +++ + + + S + Sbjct: 928 NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDS 962 Score = 36.2 bits (82), Expect = 0.13 Identities = 38/215 (17%), Positives = 72/215 (33%), Gaps = 2/215 (0%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 342 D D S + S+ S D+ N S S+ S++ S S D S+ S + Sbjct: 1062 DSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSD--SSDSSDSSDSSDSSDSSDSSD 1119 Query: 343 ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 402 SSD SS +S S + + ES S + SD+ S++ + Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1179 Query: 403 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 462 ++ + + D + S DS+ +SD + ++ Sbjct: 1180 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239 Query: 463 CGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRK 497 ++++ + + DS E++ K Sbjct: 1240 SSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274 Score = 36.2 bits (82), Expect = 0.13 Identities = 43/213 (20%), Positives = 80/213 (37%), Gaps = 4/213 (1%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 342 D D S + S+ S D+ + S S+ S++ S S D S+ S + Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSNSSDSSDSSDSSDSSD 1137 Query: 343 ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 402 SSD +SS +S S + + +S S + SD+ S++ + Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197 Query: 403 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD-QDSFLHENSLHQEESQKENM 461 ++ + + D + S DS+ +SD DS +S + +S + Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD 1257 Query: 462 PCGETAEFK-QKQSVNKGKQGKEQNQDSQTEAE 493 T++ + S +K G DS +++E Sbjct: 1258 SSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSE 1290 Score = 35.8 bits (81), Expect = 0.17 Identities = 38/212 (17%), Positives = 78/212 (36%), Gaps = 4/212 (1%) Query: 281 DIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPI 340 D D S D +S N D+ D+G + ++ + +S + ++S S Sbjct: 512 DDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571 Query: 341 REELVSSDELRQDKSSGAS--SESVQTVNQAEVESLTVKSESTGT--PGHLRSDTEHSTN 396 + SSD D S S S+S + N ++ + S+S+ + +SD+ S + Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631 Query: 397 EVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEES 456 + K+D ++ + D + S DS+ +SD S ++ Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691 Query: 457 QKENMPCGETAEFKQKQSVNKGKQGKEQNQDS 488 ++ E+++ + N +S Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723 Score = 35.4 bits (80), Expect = 0.22 Identities = 37/197 (18%), Positives = 72/197 (36%), Gaps = 2/197 (1%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 352 S SN+ E + +DS+ ++ S S D S+ S SSD Sbjct: 690 SDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDS 749 Query: 353 DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEM 412 SS SS+S + N ++ + S+S+ + S+ ++++ + +D +N Sbjct: 750 SNSSD-SSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808 Query: 413 AIKEDQIADNFQGISGPKEDST-SIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQ 471 + +D+ S +S+ S ++ DS +S +S N + Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS 868 Query: 472 KQSVNKGKQGKEQNQDS 488 S + + DS Sbjct: 869 DSSDSSNSSDSSDSSDS 885 Score = 35.4 bits (80), Expect = 0.22 Identities = 33/202 (16%), Positives = 74/202 (36%), Gaps = 6/202 (2%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 352 S SN+ + + N ++S + S++ S S D S+ S + SSD Sbjct: 912 SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDS--S 969 Query: 353 DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHL----RSDTEHSTNEVGTLCHKTDLN 408 D +S SS+S + + ++ + S+S+ + SD+ S+N + N Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029 Query: 409 NLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAE 468 + + + D + S DS++ +SD + ++ ++++ Sbjct: 1030 SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089 Query: 469 FKQKQSVNKGKQGKEQNQDSQT 490 + + + S + Sbjct: 1090 SSNSSDSSDSSDSSDSSDSSDS 1111 Score = 35.4 bits (80), Expect = 0.22 Identities = 45/222 (20%), Positives = 76/222 (34%), Gaps = 14/222 (6%) Query: 268 EILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESL 327 E DS + D D S + S+ S D+ + S S+ S++ S Sbjct: 1083 ESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSDSSN 1140 Query: 328 SEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHL 387 S D SE S + SSD SS +S S + + +S S + Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1200 Query: 388 RSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLH 447 SD+ S++ + ++ + + D + S DS++ +SD Sbjct: 1201 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSD 1260 Query: 448 ENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQ 489 S +ES Q +S N G + + DS+ Sbjct: 1261 STSDSNDESD------------SQSKSGNGNNNGSDSDSDSE 1290 Score = 35.0 bits (79), Expect = 0.29 Identities = 39/222 (17%), Positives = 78/222 (35%), Gaps = 14/222 (6%) Query: 271 DSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSED 330 DS + D D +S + S+ S D+ + S S+ S++ S S D Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913 Query: 331 VFTESELSPIREELVSSDELRQDKSSGAS--SESVQTVNQAEVESLTVKSESTGTPGHLR 388 S S E SSD SS +S S+S + N ++ + + S S+ + Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973 Query: 389 SDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHE 448 SD+ S+N + + + D + S DS+ +SD + Sbjct: 974 SDSSDSSN------------SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDS 1021 Query: 449 NSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQT 490 ++ + ++ ++++ + + S + Sbjct: 1022 SNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1063 Score = 34.7 bits (78), Expect = 0.38 Identities = 34/209 (16%), Positives = 73/209 (34%), Gaps = 1/209 (0%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSPIR 341 D + D S + S+ S D+ + S +S + S++ S S D S+ S Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSS 1037 Query: 342 EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTL 401 + SSD SS +S+ S + + +S S + SD+ S+N + Sbjct: 1038 DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSS 1097 Query: 402 CHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENM 461 ++ + + D + S DS+ +SD + + + ++ Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSS 1157 Query: 462 PCGETAEFKQKQSVNKGKQGKEQNQDSQT 490 ++++ + + S + Sbjct: 1158 DSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186 Score = 34.3 bits (77), Expect = 0.49 Identities = 45/224 (20%), Positives = 78/224 (34%), Gaps = 12/224 (5%) Query: 271 DSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSED 330 DSK S D D S SN+ + + + S+S + S++ S S D Sbjct: 637 DSKSDSSDSNSSDSSDNSD--SSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694 Query: 331 VFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSD 390 SE S + SSD D S ++S N ++ +S S + SD Sbjct: 695 SSNSSESSDSSD---SSDSDSSDSSDSSNS------NSSDSDSSNSSDSSDSSNSSDSSD 745 Query: 391 TEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD-QDSFLHEN 449 + S+N + N+ + + D + S DS++ +SD +S N Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSN 805 Query: 450 SLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAE 493 S +S + + S + + DS ++ Sbjct: 806 SSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849 Score = 34.3 bits (77), Expect = 0.49 Identities = 34/198 (17%), Positives = 74/198 (37%), Gaps = 3/198 (1%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 352 S + S+ S D+ N S S+ S++ S S + S+ S + SSD Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNS 1003 Query: 353 DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEM 412 SS SS+S + N ++ + + S S+ + SD+ S++ + N+ + Sbjct: 1004 SDSSD-SSDSSDSSNSSDSSNSSDSSNSSDSSDS--SDSSDSSDSSDSSDSSDSSNSSDS 1060 Query: 413 AIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQK 472 + D + S DS+ +SD + + ++ ++++ Sbjct: 1061 SDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1120 Query: 473 QSVNKGKQGKEQNQDSQT 490 + + + + S + Sbjct: 1121 SNSSDSSDSSDSSDSSDS 1138 Score = 34.3 bits (77), Expect = 0.49 Identities = 38/211 (18%), Positives = 78/211 (36%), Gaps = 7/211 (3%) Query: 281 DIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSP 339 D + D +S + S+ S D+ N S +S + S++ S S D S+ S Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSN 1029 Query: 340 IREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVG 399 + SSD SS SS+S + N ++ + S+S+ + SD+ S++ Sbjct: 1030 SSDSSDSSDSSDSSDSSD-SSDSSDSSNSSDSSDSSDSSDSSDS-----SDSSDSSDSSE 1083 Query: 400 TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKE 459 + N+ + + D + S DS+ +SD + + + Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143 Query: 460 NMPCGETAEFKQKQSVNKGKQGKEQNQDSQT 490 + E+++ + + + S + Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174 Score = 33.9 bits (76), Expect = 0.65 Identities = 32/208 (15%), Positives = 70/208 (33%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 342 D D +S + S+ S D+ + +S + S++ S S D S+ S Sbjct: 943 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSN 1002 Query: 343 ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 402 SSD SS +S S + + +S S + SD+ S+N + Sbjct: 1003 SSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1062 Query: 403 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 462 ++ + + D + S +S+ +SD + ++ Sbjct: 1063 SSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSN 1122 Query: 463 CGETAEFKQKQSVNKGKQGKEQNQDSQT 490 ++++ + + + S++ Sbjct: 1123 SSDSSDSSDSSDSSDSSNSSDSSDSSES 1150 Score = 33.1 bits (74), Expect = 1.1 Identities = 35/208 (16%), Positives = 69/208 (33%), Gaps = 2/208 (0%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 342 D + D S + S+ S D+ N S S+ S++ S S D S+ S E Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD--SSDSSDSSDSSDSSDSSDSSE 1083 Query: 343 ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 402 SSD SS +S S + + +S S + SD+ S++ + Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSD 1143 Query: 403 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 462 + + + D + S DS+ +SD + ++ Sbjct: 1144 SSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1203 Query: 463 CGETAEFKQKQSVNKGKQGKEQNQDSQT 490 ++++ + + + S + Sbjct: 1204 SSDSSDSSDSSDSSDSSDSSDSSDSSDS 1231 Score = 32.7 bits (73), Expect = 1.4 Identities = 44/256 (17%), Positives = 87/256 (33%), Gaps = 14/256 (5%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESEL-SPIR 341 D D S + S+ S D+ N S S+ + +S S D S S Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726 Query: 342 EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTL 401 + SSD SS +S S + + +S + S + SD+ S+N Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN----- 781 Query: 402 CHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENM 461 +D N + + D + S DS+ +SD DS +S + +S + Sbjct: 782 --SSDSN--DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS- 836 Query: 462 PCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKE 521 +++ + G N+ + + + + + ++ + + + Sbjct: 837 ---NSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSD 893 Query: 522 AKHKITSADGHIESSA 537 + S+D S+ Sbjct: 894 SSDSSNSSDSDSSDSS 909 Score = 32.7 bits (73), Expect = 1.4 Identities = 35/202 (17%), Positives = 72/202 (35%), Gaps = 4/202 (1%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSA--STAPRSTEESLSEDVFTESELSPIREELVSSDEL 350 S SN+ + DS +DS+ S + S+E S S D S+ S + SSD Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951 Query: 351 RQDKSSGAS--SESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLN 408 SS +S S S + + +S + S + SD+ S++ + + Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011 Query: 409 NLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAE 468 + + + D + S DS+ +SD + ++ ++++ Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071 Query: 469 FKQKQSVNKGKQGKEQNQDSQT 490 + + + + S + Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNS 1093 Score = 32.7 bits (73), Expect = 1.4 Identities = 35/208 (16%), Positives = 69/208 (33%), Gaps = 2/208 (0%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 342 D + D S + S+ S D+ N S S+ S++ S S D S+ S Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD--SSDSSDSSDSSDSSDSSDSSN 1056 Query: 343 ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 402 SSD SS +S S + + +S + S + SD+ S++ + Sbjct: 1057 SSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1116 Query: 403 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 462 N+ + + D + S DS+ +SD + ++ Sbjct: 1117 SSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSD 1176 Query: 463 CGETAEFKQKQSVNKGKQGKEQNQDSQT 490 +++ + + + S + Sbjct: 1177 SSNSSDSSDSSDSSDSSDSSDSSDSSDS 1204 Score = 32.3 bits (72), Expect = 1.9 Identities = 41/210 (19%), Positives = 76/210 (36%), Gaps = 16/210 (7%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 342 D + D S + S+ S ++ + S S+ ++ S S D S+ S Sbjct: 778 DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837 Query: 343 ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 402 SSD D S G+ S+S N+++ + + S+S+ + S +NE Sbjct: 838 SSDSSDS--SDSSDGSDSDSS---NRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892 Query: 403 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSD--QDSFLHENSLHQEESQKEN 460 +D +N +D+ S DS+ +SD + S +NS + S + Sbjct: 893 DSSDSSNS---------SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSD 943 Query: 461 MPCGETAEFKQKQSVNKGKQGKEQNQDSQT 490 + S + + DS + Sbjct: 944 SSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973 Score = 31.6 bits (70), Expect = 3.2 Identities = 35/210 (16%), Positives = 74/210 (35%), Gaps = 6/210 (2%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 342 D D S + S+ S D+ N S S+ S++ S S D S+ S + Sbjct: 987 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS--NSSDSSNSSDSSDSSDSSDSSD 1044 Query: 343 ELVSSDELRQDKSSGAS--SESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGT 400 SSD SS +S S+S + + ++ + SES+ + S +++ Sbjct: 1045 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104 Query: 401 LCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKEN 460 +D ++ + +D+ S DS+ +SD + ++ Sbjct: 1105 SSDSSDSSDSSDSSDSSNSSDSSD--SSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162 Query: 461 MPCGETAEFKQKQSVNKGKQGKEQNQDSQT 490 ++++ + + + S + Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1192 Score = 31.6 bits (70), Expect = 3.2 Identities = 30/198 (15%), Positives = 66/198 (33%) Query: 293 SKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQ 352 S SN+ + + + +S + S++ S S D S S + SSD Sbjct: 1049 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS 1108 Query: 353 DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEM 412 SS +S S + + +S S + SD+ S++ + ++ + Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS 1168 Query: 413 AIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQK 472 + D + S DS+ +SD + ++ ++++ Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228 Query: 473 QSVNKGKQGKEQNQDSQT 490 N+ + + S + Sbjct: 1229 SDSNESSDSSDSSDSSDS 1246 Score = 30.4 bits (67), Expect = 7.1 Identities = 41/214 (19%), Positives = 79/214 (36%), Gaps = 9/214 (4%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSPIR 341 D D S + S+ S D+ + S +S + S++ S S D S+ S Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1064 Query: 342 EELVSSDELRQDKSSGAS--SESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVG 399 + SSD SS +S S+S + N ++ + S+S+ + SD+ S++ Sbjct: 1065 DSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS-----SDSSDSSDSSD 1119 Query: 400 TLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKE 459 + ++ + + D + S DS+ +SD S ++S + S Sbjct: 1120 SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSD-SSDSSDSSDSSDSSDSS 1178 Query: 460 NMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAE 493 N + S + + DS ++ Sbjct: 1179 NSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1212 Score = 30.0 bits (66), Expect = 9.3 Identities = 30/208 (14%), Positives = 70/208 (33%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDVFTESELSPIRE 342 D + D S S++ + + +S + S+ S S D S+ S + Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020 Query: 343 ELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTLC 402 SSD SS +S S + + +S + S + SD+ S++ + Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080 Query: 403 HKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMP 462 ++ + + D + S DS+ +SD + + ++ Sbjct: 1081 SSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN 1140 Query: 463 CGETAEFKQKQSVNKGKQGKEQNQDSQT 490 ++++ + + + + S + Sbjct: 1141 SSDSSDSSESSDSSDSSDSSDSSDSSDS 1168 Score = 30.0 bits (66), Expect = 9.3 Identities = 32/209 (15%), Positives = 73/209 (34%), Gaps = 1/209 (0%) Query: 283 DQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDS-ASTAPRSTEESLSEDVFTESELSPIR 341 D + D +S + S+ S D+ + S +S + S+ S S D S+ S Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073 Query: 342 EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGTL 401 + SSD SS +S+ S + + +S S + S++ S++ + Sbjct: 1074 DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1133 Query: 402 CHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENM 461 N+ + + + + S DS+ +SD + + ++ Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193 Query: 462 PCGETAEFKQKQSVNKGKQGKEQNQDSQT 490 ++++ + + + S + Sbjct: 1194 DSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222 >gi|87299628 biorientation of chromosomes in cell division 1-like [Homo sapiens] Length = 3051 Score = 40.0 bits (92), Expect = 0.009 Identities = 78/395 (19%), Positives = 143/395 (36%), Gaps = 80/395 (20%) Query: 258 EEVMSAAMYKEILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSAS 317 +E +A E ++K E + D K+ T + + + D+G + Sbjct: 213 QEASAARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLE 272 Query: 318 TAPRSTEES---------------------LSEDVFTES-----------ELSPIREELV 345 TAP+S E S L++DV ES E P E Sbjct: 273 TAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKG 332 Query: 346 SSDELRQDKSS-----GASSESVQTV------NQAEVESLTVKSESTGTPGH-------- 386 + +++K+ SE Q V + EVESL + SE Sbjct: 333 ERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKED 392 Query: 387 ---LRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQ---GISGPKE--------- 431 + SD + T+ + H +DL++ E +E+ + + I+ E Sbjct: 393 FSLIDSDVDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTK 452 Query: 432 ----DSTSIKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQD 487 DS+ K S + +++H+ L+ + + E +++QS+ K K+ + + Sbjct: 453 TQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSD---DELTVEQRRQSIAKEKEERLLRRQ 509 Query: 488 SQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALLKE--KQRH 545 E E ++ K + +K + + V +E+ K +A +KE K+R Sbjct: 510 INREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLE-----PKAARIKEVLKERK 564 Query: 546 RLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKK 580 L K + L + V + S QQY + K+ Sbjct: 565 VLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKE 599 Score = 36.2 bits (82), Expect = 0.13 Identities = 55/259 (21%), Positives = 99/259 (38%), Gaps = 44/259 (16%) Query: 290 FCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESLSEDV--------FTESELSPIR 341 + S+ N + +DSRI A T P T+E S D+ T S S + Sbjct: 2777 YLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVM 2836 Query: 342 EELVSSDELRQDKSSGASSE--SVQTVNQAEVESLTVKSESTGTPGHLRSDT-------- 391 EE DE +++G E T+ E + + G P +T Sbjct: 2837 EE---KDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDS 2893 Query: 392 ---------EHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSI--KGNS 440 E S + +TD +N E A +++ N G ++ TS+ +G Sbjct: 2894 KTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISN---DDGEEKIVTSVRRRGRK 2950 Query: 441 DQDSF-LHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQD------SQTEAE 493 + S + +++ E +K + E K++Q ++ ++ +E+++ S T +E Sbjct: 2951 PKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSE 3010 Query: 494 ELRKLWKTHTMQQTKQQRE 512 R KT K++RE Sbjct: 3011 AQRS--KTQLSPSIKRKRE 3027 Score = 32.7 bits (73), Expect = 1.4 Identities = 33/150 (22%), Positives = 66/150 (44%), Gaps = 20/150 (13%) Query: 377 KSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGP-KEDSTS 435 K++S+ T G RS + + +L K ++ +KE ++ + +S K+DS + Sbjct: 525 KTKSSKTKGQGRSSVDLEESSTKSLEPKAA--RIKEVLKERKVLEKKVALSKKRKKDSRN 582 Query: 436 IKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEEL 495 ++ NS + EE KE + +T+E +K+ ++ K+ K + S+ Sbjct: 583 VEENSKKKQ-------QYEEDSKETL---KTSEHCEKEKISSSKELKHVHAKSEPSKPAR 632 Query: 496 RKLWKTHTMQQTKQQRENIQQVSQKEAKHK 525 R H + + K + S+ E +HK Sbjct: 633 RLSESLHVVDENKNE-------SKLEREHK 655 Score = 30.0 bits (66), Expect = 9.3 Identities = 46/243 (18%), Positives = 94/243 (38%), Gaps = 25/243 (10%) Query: 295 KMTGSNTEEIDSRIRDAGNDSASTAP----RSTEESLSEDV---------FTESELSPIR 341 K G + +++ +++ A+T ++TEE+ SE F E+ + P+ Sbjct: 915 KTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVL 974 Query: 342 EELVSSDELRQ-DKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHSTNEVGT 400 E SS Q D S A + +++ +S + + E + GH +HS+ ++ Sbjct: 975 ETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDI-- 1032 Query: 401 LCHKTDLNNLE--MAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQK 458 K D N + + D + +G S E S + ++ SL QE ++ Sbjct: 1033 --KKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENR-----RGSLSQEMAKG 1085 Query: 459 ENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVS 518 E T S+ + K+ + + E E+ + + + ++N S Sbjct: 1086 EEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNS 1145 Query: 519 QKE 521 Q++ Sbjct: 1146 QQD 1148 >gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] Length = 1220 Score = 39.7 bits (91), Expect = 0.012 Identities = 51/242 (21%), Positives = 98/242 (40%), Gaps = 32/242 (13%) Query: 403 HKTDLNNLEMAIKEDQIA-----DNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQ 457 H+ L L+ A++ ++A D + KE + ++ ++ L E + Q Sbjct: 561 HRDSLVTLKRALEAKELARQHLRDQLDEVE--KETRSKLQEIDIFNNQLKELREIHNKQQ 618 Query: 458 KENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQR-ENIQQ 516 + E KQK+ K + ++Q +++Q A+E K W H Q+ + QR + + Sbjct: 619 LQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHE 678 Query: 517 VSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKP-MRKTFVSQASATMQQYA 575 + + + + DG + ++K H+ KP ++ + + + A Sbjct: 679 EEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH--QEPAKPAVQAPWSTAEKGPLTISA 736 Query: 576 QRDKKHEYWFAV-PQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKK---IEESET 631 Q + K Y+ A+ P E H E T +PG IV+ K ++ES+T Sbjct: 737 QENVKVVYYRALYPFESRSH-----------------DEITIQPGDIVMVKGEWVDESQT 779 Query: 632 IE 633 E Sbjct: 780 GE 781 >gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] Length = 1721 Score = 39.7 bits (91), Expect = 0.012 Identities = 51/242 (21%), Positives = 98/242 (40%), Gaps = 32/242 (13%) Query: 403 HKTDLNNLEMAIKEDQIA-----DNFQGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQ 457 H+ L L+ A++ ++A D + KE + ++ ++ L E + Q Sbjct: 561 HRDSLVTLKRALEAKELARQHLRDQLDEVE--KETRSKLQEIDIFNNQLKELREIHNKQQ 618 Query: 458 KENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQR-ENIQQ 516 + E KQK+ K + ++Q +++Q A+E K W H Q+ + QR + + Sbjct: 619 LQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQEDEHQRPRKLHE 678 Query: 517 VSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKP-MRKTFVSQASATMQQYA 575 + + + + DG + ++K H+ KP ++ + + + A Sbjct: 679 EEKLKREESVKKKDGEEKGKQEAQDKLGRLFHQH--QEPAKPAVQAPWSTAEKGPLTISA 736 Query: 576 QRDKKHEYWFAV-PQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKK---IEESET 631 Q + K Y+ A+ P E H E T +PG IV+ K ++ES+T Sbjct: 737 QENVKVVYYRALYPFESRSH-----------------DEITIQPGDIVMVKGEWVDESQT 779 Query: 632 IE 633 E Sbjct: 780 GE 781 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 39.7 bits (91), Expect = 0.012 Identities = 50/199 (25%), Positives = 85/199 (42%), Gaps = 24/199 (12%) Query: 321 RSTEESLS--EDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKS 378 RS EE+L D E+ I +L +EL+ E +T+++ + S Sbjct: 1692 RSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMH--LKEHQETIDKLR----GIVS 1745 Query: 379 ESTGTPGHLRSDTEHSTNEVGT--LCHKTDLNNLEMAIKEDQ-IADNFQGISGPKEDSTS 435 E T +++ D EHS + + L + +L M +KE Q D +GI K D S Sbjct: 1746 EKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLS 1805 Query: 436 IKGNSDQDSFLHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEEL 495 N +D ENS + + + + + E K+ VN + Q +E E+L Sbjct: 1806 ---NMQKDL---ENSNAKLQEKIQELKANEHQLITLKKDVN-------ETQKKVSEMEQL 1852 Query: 496 RKLWKTHTMQQTKQQRENI 514 +K K ++ +K + EN+ Sbjct: 1853 KKQIKDQSLTLSKLEIENL 1871 Score = 35.0 bits (79), Expect = 0.29 Identities = 43/194 (22%), Positives = 75/194 (38%), Gaps = 44/194 (22%) Query: 367 NQAEVESLTVKSESTGTPGH---LRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNF 423 N+A E + + SE P LR + + + E+ + + D E+ KE ++ Sbjct: 736 NEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLL 795 Query: 424 QGISGPKEDSTSIKGN--SDQDSFLHENSLHQEESQKENMPCGE---------------- 465 + I K+D + + N S F + +LH + QK M E Sbjct: 796 EEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQ 855 Query: 466 ----------------TAEFKQK-----QSVNKGKQGKEQ--NQDSQTEAEELRKLWKTH 502 T E ++K + +N+ +Q KEQ N+DS + E K T Sbjct: 856 KFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITE 915 Query: 503 TMQQTKQQRENIQQ 516 +QQT ++ + + Q Sbjct: 916 KLQQTLEEVKTLTQ 929 >gi|117414154 sodium channel associated protein 2 isoform b [Homo sapiens] Length = 939 Score = 39.3 bits (90), Expect = 0.015 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 8/124 (6%) Query: 480 QGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALL 539 + K+Q +D L K + Q+ +QQ I+ + + E K + ++ ++L Sbjct: 416 KAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLH 475 Query: 540 KEK-QRHRLHKFLCLRVGKPMR----KTFVSQA---SATMQQYAQRDKKHEYWFAVPQER 591 +E+ Q +LH+ L L+ + + + F + A A ++ A+ +KKHE QE+ Sbjct: 476 REREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEK 535 Query: 592 TDHL 595 D L Sbjct: 536 IDVL 539 Score = 32.0 bits (71), Expect = 2.5 Identities = 47/208 (22%), Positives = 83/208 (39%), Gaps = 36/208 (17%) Query: 327 LSEDVFTESELSPIR-EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG 385 +SE ES + +R E V EL Q SS A + +A++ESL+ ++E Sbjct: 656 ISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKL---EAQIESLSRENEC----- 707 Query: 386 HLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSF 445 LR E ++ + C D + +D + + + I +E T I+ Sbjct: 708 -LRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIE-------- 758 Query: 446 LHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKT---- 501 QE+ +++ E E ++ + K K K+Q + + E EE+RK + T Sbjct: 759 ----KCTQEQLDEKSSQLDEVLEKLERHNERKEKL-KQQLKGKEVELEEIRKAYSTLNRK 813 Query: 502 ---------HTMQQTKQQRENIQQVSQK 520 H Q K+ +E + +K Sbjct: 814 WHDKGELLCHLETQVKEVKEKFENKEKK 841 >gi|117414162 sodium channel associated protein 2 isoform a [Homo sapiens] Length = 1032 Score = 39.3 bits (90), Expect = 0.015 Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 8/124 (6%) Query: 480 QGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSADGHIESSALL 539 + K+Q +D L K + Q+ +QQ I+ + + E K + ++ ++L Sbjct: 509 KAKDQQEDHLKHLRTLEKTLEKMERQKRQQQAAQIRLIQEVELKASAADREIYLLRTSLH 568 Query: 540 KEK-QRHRLHKFLCLRVGKPMR----KTFVSQA---SATMQQYAQRDKKHEYWFAVPQER 591 +E+ Q +LH+ L L+ + + + F + A A ++ A+ +KKHE QE+ Sbjct: 569 REREQAQQLHQLLALKEQEHRKELETREFFTDADFQDALAKEIAKEEKKHEQMIKEYQEK 628 Query: 592 TDHL 595 D L Sbjct: 629 IDVL 632 Score = 32.0 bits (71), Expect = 2.5 Identities = 47/208 (22%), Positives = 83/208 (39%), Gaps = 36/208 (17%) Query: 327 LSEDVFTESELSPIR-EELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPG 385 +SE ES + +R E V EL Q SS A + +A++ESL+ ++E Sbjct: 749 ISELAAKESLIFGLRTERKVWGHELAQQGSSLAQNRGKL---EAQIESLSRENEC----- 800 Query: 386 HLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSF 445 LR E ++ + C D + +D + + + I +E T I+ Sbjct: 801 -LRKTNESDSDALRIKCKIIDDQTETIRKLKDCLQEKDEHIKRLQEKITEIE-------- 851 Query: 446 LHENSLHQEESQKENMPCGETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKT---- 501 QE+ +++ E E ++ + K K K+Q + + E EE+RK + T Sbjct: 852 ----KCTQEQLDEKSSQLDEVLEKLERHNERKEKL-KQQLKGKEVELEEIRKAYSTLNRK 906 Query: 502 ---------HTMQQTKQQRENIQQVSQK 520 H Q K+ +E + +K Sbjct: 907 WHDKGELLCHLETQVKEVKEKFENKEKK 934 >gi|217330641 IWS1 homolog [Homo sapiens] Length = 819 Score = 38.9 bits (89), Expect = 0.020 Identities = 58/275 (21%), Positives = 109/275 (39%), Gaps = 34/275 (12%) Query: 269 ILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEE------IDSRIRDA---GNDSASTA 319 + DS+ E L ++ + H +K + S +EE DS D G+DS S Sbjct: 66 VTDSENDEPLNLNASDSESEEL-HRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEE 124 Query: 320 PR------STEESLSEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVES 373 R S E L ++SE + + S E+ + + S AS + + ++ Sbjct: 125 TRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKPQISD 184 Query: 374 LTVKSESTGTPGHLRSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDS 433 SES P H SD+E NE +D + E+ + Q++D+ E+ Sbjct: 185 ----SESEEPPRHQASDSE---NEEPPKPRMSDSESEELP--KPQVSDS------ESEEP 229 Query: 434 TSIKGNSDQDSFLHENSLHQEESQ---KENMPCGETAEFKQKQSVNKGKQGKEQNQDSQT 490 + + ++ L + + ES+ + E E + + + + +NQ S + Sbjct: 230 PRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDS 289 Query: 491 EAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHK 525 E EEL K + + + Q+ ++ ++HK Sbjct: 290 ENEELPKPRVSDSESEGPQKGPASDSETEDASRHK 324 >gi|195976782 Paf1/RNA polymerase II complex component [Homo sapiens] Length = 710 Score = 38.9 bits (89), Expect = 0.020 Identities = 59/299 (19%), Positives = 122/299 (40%), Gaps = 43/299 (14%) Query: 304 IDSRIRDAGNDS------ASTAPRSTEESLSEDVFTESELSPIREELVSSDELRQDKSSG 357 IDS D+G+D S A R +S E + P+ + SSD D Sbjct: 51 IDSDTEDSGSDENLDQELLSLAKRKRSDS-------EEKEPPVSQPAASSDSETSDSDDE 103 Query: 358 ASSESVQTVNQAEVESL----TVKSESTGTPGHLRSD----TEHSTNEVGTLCHK----- 404 + S + + + + T+K ++ T SD E S E G + Sbjct: 104 WTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSS 163 Query: 405 TDLNNLEMAIKEDQIADNF-QGISGPKEDSTSIKGNSDQDSFLHENSLHQEESQKENMPC 463 + ++ + + ++++ D + + + G +ED ++ ++++ E L ++E + Sbjct: 164 SSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQMTEKE---REQELFNRIEKREVLK- 219 Query: 464 GETAEFKQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAK 523 E K+K K K+ KE+ + Q E +E +KL + Q T +E + + Sbjct: 220 -RRFEIKKKLKTAKKKEKKEKKK-KQEEEQEKKKLTQIQESQVTSHNKER-----RSKRD 272 Query: 524 HKITSADGHIESSALLKEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYAQRDKKHE 582 K+ +E +EK+++R + L + +P++ S+ + ++ + DK E Sbjct: 273 EKLDKKSQAMEELKAEREKRKNRTAELLAKK--QPLK---TSEVYSDDEEEEEDDKSSE 326 >gi|119226220 membrane-spanning 4-domains, subfamily A, member 14 isoform 2 [Homo sapiens] Length = 662 Score = 38.9 bits (89), Expect = 0.020 Identities = 50/226 (22%), Positives = 96/226 (42%), Gaps = 23/226 (10%) Query: 335 SELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHS 394 SE+ +E S +EL + KSS S + QT + ++ ++ G +S HS Sbjct: 445 SEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQ----KSSKRHS 500 Query: 395 TNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSF-LHENSLHQ 453 ++ +L+ IK+ PK S + +Q L + Sbjct: 501 LDQQSKGWQSPKQKSLDQQIKD---------WLSPKRHSVDKQAQLNQTKEQLPDQQAED 551 Query: 454 EESQKENMPCGETAEFKQK-QSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRE 512 ++++ E P G++ + + K Q +K + K+Q QD QTE + ++ + K Q + Sbjct: 552 QQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQE------KKSPKGQFQ 605 Query: 513 NIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKP 558 N+Q Q+ K+ +S + +++ Q + HK L+ G+P Sbjct: 606 NVQAEGQQAQVEKVPKLLCQ-DSESQIQQYQFWQFHKG-NLQAGQP 649 >gi|119226217 membrane-spanning 4-domains, subfamily A, member 14 isoform 1 [Homo sapiens] Length = 679 Score = 38.9 bits (89), Expect = 0.020 Identities = 50/226 (22%), Positives = 96/226 (42%), Gaps = 23/226 (10%) Query: 335 SELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHLRSDTEHS 394 SE+ +E S +EL + KSS S + QT + ++ ++ G +S HS Sbjct: 462 SEVMEETKEWKSEEELHRRKSSRRHSLNQQTKALQYLRRHSLDVQAKGQ----KSSKRHS 517 Query: 395 TNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSF-LHENSLHQ 453 ++ +L+ IK+ PK S + +Q L + Sbjct: 518 LDQQSKGWQSPKQKSLDQQIKD---------WLSPKRHSVDKQAQLNQTKEQLPDQQAED 568 Query: 454 EESQKENMPCGETAEFKQK-QSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRE 512 ++++ E P G++ + + K Q +K + K+Q QD QTE + ++ + K Q + Sbjct: 569 QQAKGEQYPEGQSKDGQVKDQQTDKEQNSKKQTQDQQTEDQPAQE------KKSPKGQFQ 622 Query: 513 NIQQVSQKEAKHKITSADGHIESSALLKEKQRHRLHKFLCLRVGKP 558 N+Q Q+ K+ +S + +++ Q + HK L+ G+P Sbjct: 623 NVQAEGQQAQVEKVPKLLCQ-DSESQIQQYQFWQFHKG-NLQAGQP 666 >gi|24415404 MDN1, midasin homolog [Homo sapiens] Length = 5596 Score = 38.9 bits (89), Expect = 0.020 Identities = 88/468 (18%), Positives = 163/468 (34%), Gaps = 76/468 (16%) Query: 268 EILDSKIKESLPIDIDQLSGRDFCHSKKMTGSNTEEIDSRIRDAGNDSASTAPRSTEESL 327 E LD + + L +D + +G + +++ N EI + +AG+++ T+++ Sbjct: 4877 EALD--LPDDLNLDSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNE 4934 Query: 328 SEDVFTESELSPIREELVSSDELRQDKSSGASSESVQTVNQAEVESLTVKSESTGTPGHL 387 S+ E E P ++ +E + +GA + E Sbjct: 4935 SQSP-QEPEEGPSEDDKAEGEE---EMDTGADDQDGDAAQHPE----------------- 4973 Query: 388 RSDTEHSTNEVGTLCHKTDLNNLEMAIKEDQIADNFQGISGPKEDSTSIKGNSDQDSFLH 447 EHS + ++ K D+ AD G +GP + + +++ Sbjct: 4974 ----EHSEEQQQSVEEK------------DKEADEEGGENGPADQGFQPQEEEEREDSDT 5017 Query: 448 ENSLHQEESQKENMPCGETA--EFKQKQSVN------KGKQGKEQNQDSQTEAEELRKLW 499 E + + +KE+ CG+T + Q++ + +QGKE++ +A + Sbjct: 5018 EEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHE 5077 Query: 500 KTHTMQQTKQQ--RENIQQVSQK--------------EAKHK---ITSADGHIESS-ALL 539 Q Q+ R+N Q +K E HK D H E A Sbjct: 5078 SNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQ 5137 Query: 540 KEKQRHRLHKFLCLRVGKPMRKTFVSQASATMQQYA-------QRDKKHEYWFAVPQERT 592 + Q F ++ G ++ QQ + Q +++ E +E+ Sbjct: 5138 PQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQE 5197 Query: 593 DHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWEITTREDI 652 + A Q PE T V + ++E +D A +E E E Sbjct: 5198 EFKAADVEQLKPEEIKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERS 5257 Query: 653 NSKQVATVKADLESESFRPNLSDPSELLLPDQIEKLTKHLPPRTIGYP 700 + T L F+P L D +E L ++E+ + PR G P Sbjct: 5258 RESTIHTAHQFLMDTIFQPFLKDVNE--LRQELERQLEMWQPRESGNP 5303 >gi|189217876 sal-like 1 isoform b [Homo sapiens] Length = 1227 Score = 38.5 bits (88), Expect = 0.026 Identities = 49/192 (25%), Positives = 74/192 (38%), Gaps = 34/192 (17%) Query: 51 GSPPHRPPAPSSPEG--PDTGQ--KKTLDKKDGRRMSFQK--PKGTIEYTVES----RDS 100 G P+ P S E DTG +K D D + P+G+I T +S +DS Sbjct: 694 GQIPNTPVPDSYSESMESDTGSFDEKNFDDLDNFSDENMEDCPEGSIPDTPKSADASQDS 753 Query: 101 LNSIALKFDTTP-----NELVQLN-----------KLFSRAVVTGQVLYVPDPEYVSSVE 144 L+S L + + N++ +N K + G VL +E Sbjct: 754 LSSSPLPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDME 813 Query: 145 S--------SPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGIRPARVVSSTS 196 S S S S + LSP++S EF K+ + + P A PS G+ P V Sbjct: 814 SQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAVPSEFANGLSPTPVNGGAL 873 Query: 197 EEEEAFTEKFLK 208 + + EK +K Sbjct: 874 DLTSSHAEKIIK 885 >gi|118442837 sal-like 1 isoform a [Homo sapiens] Length = 1324 Score = 38.5 bits (88), Expect = 0.026 Identities = 49/192 (25%), Positives = 74/192 (38%), Gaps = 34/192 (17%) Query: 51 GSPPHRPPAPSSPEG--PDTGQ--KKTLDKKDGRRMSFQK--PKGTIEYTVES----RDS 100 G P+ P S E DTG +K D D + P+G+I T +S +DS Sbjct: 791 GQIPNTPVPDSYSESMESDTGSFDEKNFDDLDNFSDENMEDCPEGSIPDTPKSADASQDS 850 Query: 101 LNSIALKFDTTP-----NELVQLN-----------KLFSRAVVTGQVLYVPDPEYVSSVE 144 L+S L + + N++ +N K + G VL +E Sbjct: 851 LSSSPLPLEMSSIAALENQMKMINAGLAEQLQASLKSVENGSIEGDVLTNDSSSVGGDME 910 Query: 145 S--------SPSLSPVSPLSPTSSEAEFDKTTNPDVHPTEATPSSTFTGIRPARVVSSTS 196 S S S S + LSP++S EF K+ + + P A PS G+ P V Sbjct: 911 SQSAGSPAISESTSSMQALSPSNSTQEFHKSPSIEEKPQRAVPSEFANGLSPTPVNGGAL 970 Query: 197 EEEEAFTEKFLK 208 + + EK +K Sbjct: 971 DLTSSHAEKIIK 982 >gi|8922940 gamma-taxilin [Homo sapiens] Length = 528 Score = 38.5 bits (88), Expect = 0.026 Identities = 43/229 (18%), Positives = 99/229 (43%), Gaps = 28/229 (12%) Query: 470 KQKQSVNKGKQGKEQNQDSQTEAEELRKLWKTHTMQQTKQQRENIQQVSQKEAKHKITSA 529 KQ Q V + + ++ + +L L + + EN+QQ ++E + K +A Sbjct: 183 KQAQIVKEKVHLQSEHSKAILARSKLESLCRELQRHNKTLKEENMQQAREEEERRKEATA 242 Query: 530 DGHIESSALLKEKQRHRLHKFLC----LRVGKPMRKTFVSQASATMQQYAQRDKKHEYWF 585 I + + ++H +H + +G+ ++K ++QYA R++ + F Sbjct: 243 HFQITLDEIQAQLEQHDIHNAKLRQENIELGEKLKK--------LIEQYALREEHIDKVF 294 Query: 586 AVPQERTDHLYAFFIQWSPEIYAEDTGEYTREPGFIVVKKIEESETIEDSSNQAAAREWE 645 +E L +Q + ++ E ++ RE F++ + E + ++E Sbjct: 295 K-RKELQQQLVDAKLQQTTQLIKEADEKHQREREFLLKEATE------------SRHKYE 341 Query: 646 ITTREDINSKQVATVKADLESESFRPNLSDPSELL--LPDQIEKLTKHL 692 ++++ KQ ++ D + E F+ ++ +EL ++EK+TK + Sbjct: 342 QMKQQEVQLKQQLSLYMD-KFEEFQTTMAKSNELFTTFRQEMEKMTKKI 389 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.129 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 33,287,183 Number of Sequences: 37866 Number of extensions: 1633308 Number of successful extensions: 8342 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 58 Number of HSP's successfully gapped in prelim test: 366 Number of HSP's that attempted gapping in prelim test: 7215 Number of HSP's gapped (non-prelim): 1296 length of query: 839 length of database: 18,247,518 effective HSP length: 111 effective length of query: 728 effective length of database: 14,044,392 effective search space: 10224317376 effective search space used: 10224317376 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.