Search of human proteins with 194294543

Search of human proteins with 194294543

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|194294543 alpha 3 type IV collagen binding protein isoform 3
[Homo sapiens]
         (752 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|194294543 alpha 3 type IV collagen binding protein isoform 3 ...  1535   0.0  
gi|5031717 alpha 3 type IV collagen binding protein isoform 1 [H...  1280   0.0  
gi|14165452 alpha 3 type IV collagen binding protein isoform 2 [...  1217   0.0  
gi|4505531 oxysterol binding protein [Homo sapiens]                    87   4e-17
gi|54792084 pleckstrin homology domain containing, family A (pho...    86   1e-16
gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]       84   5e-16
gi|20070331 oxysterol binding protein-like 9 isoform e [Homo sap...    83   1e-15
gi|22547173 oxysterol binding protein-like 9 isoform d [Homo sap...    83   1e-15
gi|14249174 pleckstrin homology domain containing, family A (pho...    82   2e-15
gi|22547176 oxysterol binding protein-like 9 isoform f [Homo sap...    82   2e-15
gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]           67   8e-11
gi|19923812 oxysterol-binding protein-like protein 10 [Homo sapi...    64   5e-10
gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo sa...    60   1e-08
gi|55741447 pleckstrin homology domain containing, family H (wit...    52   2e-06
gi|217416392 pleckstrin homology domain containing, family H (wi...    52   2e-06
gi|93102364 SWAP-70 protein [Homo sapiens]                             51   5e-06
gi|29788755 SET binding factor 2 [Homo sapiens]                        49   2e-05
gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo sa...    46   1e-04
gi|116812600 START domain containing 10 [Homo sapiens]                 46   1e-04
gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo sa...    46   1e-04
gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]             45   3e-04
gi|239735519 SET binding factor 1 [Homo sapiens]                       44   4e-04
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    43   0.001
gi|154146216 pleckstrin homology domain containing, family A (ph...    43   0.001
gi|156151415 phosphatidylcholine transfer protein isoform 1 [Hom...    43   0.001
gi|151301035 START domain containing 7 [Homo sapiens]                  42   0.003
gi|154354979 myosin X [Homo sapiens]                                   41   0.004
gi|21735584 oxysterol-binding protein-like protein 3 isoform d [...    41   0.004
gi|21735582 oxysterol-binding protein-like protein 3 isoform c [...    41   0.004
gi|21735580 oxysterol-binding protein-like protein 3 isoform b [...    41   0.004

>gi|194294543 alpha 3 type IV collagen binding protein isoform 3
           [Homo sapiens]
          Length = 752

 Score = 1535 bits (3974), Expect = 0.0
 Identities = 752/752 (100%), Positives = 752/752 (100%)

Query: 1   MQHSCIPTPPSPFSAPPAFLPVVTRESRRGLSSGGSAGRNAGVTATAAAADGWKGRLPSP 60
           MQHSCIPTPPSPFSAPPAFLPVVTRESRRGLSSGGSAGRNAGVTATAAAADGWKGRLPSP
Sbjct: 1   MQHSCIPTPPSPFSAPPAFLPVVTRESRRGLSSGGSAGRNAGVTATAAAADGWKGRLPSP 60

Query: 61  LVLLPRSARCQARRRRGGRTSSLLLLPPTPERALFASPSPDPSPRGLGASSGAAEGAGAG 120
           LVLLPRSARCQARRRRGGRTSSLLLLPPTPERALFASPSPDPSPRGLGASSGAAEGAGAG
Sbjct: 61  LVLLPRSARCQARRRRGGRTSSLLLLPPTPERALFASPSPDPSPRGLGASSGAAEGAGAG 120

Query: 121 LLLGCRASMSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNAL 180
           LLLGCRASMSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNAL
Sbjct: 121 LLLGCRASMSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNAL 180

Query: 181 SYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAI 240
           SYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAI
Sbjct: 181 SYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAI 240

Query: 241 EQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILC 300
           EQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILC
Sbjct: 241 EQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILC 300

Query: 301 RQVDTLQKYFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVT 360
           RQVDTLQKYFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVT
Sbjct: 301 RQVDTLQKYFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVT 360

Query: 361 PKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYK 420
           PKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYK
Sbjct: 361 PKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYK 420

Query: 421 NAMTELKKKSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTS 480
           NAMTELKKKSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTS
Sbjct: 421 NAMTELKKKSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTS 480

Query: 481 LPSGDAFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDV 540
           LPSGDAFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDV
Sbjct: 481 LPSGDAFSSVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDV 540

Query: 541 GGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWE 600
           GGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWE
Sbjct: 541 GGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWE 600

Query: 601 TTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFS 660
           TTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFS
Sbjct: 601 TTIENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFS 660

Query: 661 VDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPAS 720
           VDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPAS
Sbjct: 661 VDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPAS 720

Query: 721 VLRAVAKREYPKFLKRFTSYVQEKTAGKPILF 752
           VLRAVAKREYPKFLKRFTSYVQEKTAGKPILF
Sbjct: 721 VLRAVAKREYPKFLKRFTSYVQEKTAGKPILF 752


>gi|5031717 alpha 3 type IV collagen binding protein isoform 1 [Homo
           sapiens]
          Length = 624

 Score = 1280 bits (3313), Expect = 0.0
 Identities = 624/624 (100%), Positives = 624/624 (100%)

Query: 129 MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDE 188
           MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDE
Sbjct: 1   MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDE 60

Query: 189 TEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESG 248
           TEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESG
Sbjct: 61  TEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESG 120

Query: 249 YGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQK 308
           YGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQK
Sbjct: 121 YGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQK 180

Query: 309 YFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGID 368
           YFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGID
Sbjct: 181 YFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGID 240

Query: 369 FKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKK 428
           FKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKK
Sbjct: 241 FKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKK 300

Query: 429 KSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFS 488
           KSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFS
Sbjct: 301 KSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFS 360

Query: 489 SVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDVGGDANWQL 548
           SVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDVGGDANWQL
Sbjct: 361 SVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDVGGDANWQL 420

Query: 549 VVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHV 608
           VVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHV
Sbjct: 421 VVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHV 480

Query: 609 VETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPL 668
           VETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPL
Sbjct: 481 VETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPL 540

Query: 669 NNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKR 728
           NNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKR
Sbjct: 541 NNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKR 600

Query: 729 EYPKFLKRFTSYVQEKTAGKPILF 752
           EYPKFLKRFTSYVQEKTAGKPILF
Sbjct: 601 EYPKFLKRFTSYVQEKTAGKPILF 624


>gi|14165452 alpha 3 type IV collagen binding protein isoform 2
           [Homo sapiens]
          Length = 598

 Score = 1217 bits (3150), Expect = 0.0
 Identities = 598/624 (95%), Positives = 598/624 (95%), Gaps = 26/624 (4%)

Query: 129 MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDE 188
           MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDE
Sbjct: 1   MSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDE 60

Query: 189 TEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESG 248
           TEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESG
Sbjct: 61  TEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESG 120

Query: 249 YGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQK 308
           YGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQK
Sbjct: 121 YGSESSLRRHGSMVSLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQK 180

Query: 309 YFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGID 368
           YFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGID
Sbjct: 181 YFDACADAVSKDELQRDKVVEDDEDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGID 240

Query: 369 FKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKK 428
           FKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKK
Sbjct: 241 FKGEAITFKATTAGILATLSHCIELMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKK 300

Query: 429 KSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFS 488
           KSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFS
Sbjct: 301 KSHFGGPDYEEGPNSLINEEEFFDAVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFS 360

Query: 489 SVGTHRFVQKPYSRSSSMSSIDLVSASDDVHRFSSQVEEMVQNHMTYSLQDVGGDANWQL 548
           SVGTHRFVQK                          VEEMVQNHMTYSLQDVGGDANWQL
Sbjct: 361 SVGTHRFVQK--------------------------VEEMVQNHMTYSLQDVGGDANWQL 394

Query: 549 VVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHV 608
           VVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHV
Sbjct: 395 VVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTIENFHV 454

Query: 609 VETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPL 668
           VETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPL
Sbjct: 455 VETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDHDSAPL 514

Query: 669 NNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKR 728
           NNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKR
Sbjct: 515 NNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVLRAVAKR 574

Query: 729 EYPKFLKRFTSYVQEKTAGKPILF 752
           EYPKFLKRFTSYVQEKTAGKPILF
Sbjct: 575 EYPKFLKRFTSYVQEKTAGKPILF 598


>gi|4505531 oxysterol binding protein [Homo sapiens]
          Length = 807

 Score = 87.4 bits (215), Expect = 4e-17
 Identities = 70/209 (33%), Positives = 101/209 (48%), Gaps = 22/209 (10%)

Query: 106 GLGASSG---AAEGAGAGLLLGCRASMSDNQSWNSSGSEEDPETESGPPVERCGVLSKWT 162
           G GA+SG   AA   G G   G  A+     +  + GS       SG   E  G L KWT
Sbjct: 42  GSGAASGTVVAAAAGGPGPGAGGVAAAGPAPAPPTGGSGGSGAGGSGSARE--GWLFKWT 99

Query: 163 NYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDS- 221
           NYI G+Q RW VL N  LSYY+S+ E  + CRG+I L+ A IT    D C F IS   + 
Sbjct: 100 NYIKGYQRRWFVLSNGLLSYYRSKAEMRHTCRGTINLATANITVE--DSCNFIISNGGAQ 157

Query: 222 VWYLRAQDPDHRQQWIDAIEQHKTES--------GYGSESSLRR------HGSMVSLVSG 267
            ++L+A     RQ+W+ A+E  K ++          G E S+ +        ++ +L S 
Sbjct: 158 TYHLKASSEVERQRWVTALELAKAKAVKMLAESDESGDEESVSQTDKTELQNTLRTLSSK 217

Query: 268 ASGYSATSTSSFKKGHSLREKLAEMETFR 296
               S  +    K G +L+  L+E+E+ +
Sbjct: 218 VEDLSTCNDLIAKHGTALQRSLSELESLK 246


>gi|54792084 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 3 [Homo
           sapiens]
          Length = 300

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 51/161 (31%), Positives = 81/161 (50%), Gaps = 33/161 (20%)

Query: 156 GVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFD 215
           GVL KWTNY+ GWQ RW VL N  LSYY S+D+   G +GSI ++   I  H  D  R +
Sbjct: 3   GVLYKWTNYLTGWQPRWFVLDNGILSYYDSQDDVCKGSKGSIKMAVCEIKVHSADNTRME 62

Query: 216 ISV-NDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSAT 274
           + +  +  +Y++A +   RQ+W+ A+                          G+S    T
Sbjct: 63  LIIPGEQHFYMKAVNAAERQRWLVAL--------------------------GSSKACLT 96

Query: 275 STSSFKK------GHSLREKLAEMETFRDILCRQVDTLQKY 309
            T + K+        SL+ K++E+  + D+L +QV T+Q++
Sbjct: 97  DTRTKKEKEISETSESLKTKMSELRLYCDLLMQQVHTIQEF 137


>gi|13540513 oxysterol binding protein 2 isoform a [Homo sapiens]
          Length = 916

 Score = 84.0 bits (206), Expect = 5e-16
 Identities = 97/394 (24%), Positives = 157/394 (39%), Gaps = 71/394 (18%)

Query: 156 GVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFD 215
           G L KWTNY+ G+Q RW VL N  LSYY+++ E  + CRG+I LS A I   D   C   
Sbjct: 187 GWLLKWTNYLKGYQRRWFVLGNGLLSYYRNQGEMAHTCRGTINLSTAHIDTED--SCGIL 244

Query: 216 ISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATS 275
           ++     ++L+A     RQQWI A+E  K ++         R  +  S  SG    + T 
Sbjct: 245 LTSGARSYHLKASSEVDRQQWITALELAKAKAV--------RVMNTHSDDSGDDDEATTP 296

Query: 276 TSSFKKGHSLRE---KLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDE 332
               +  H+L+    KL ++ T  D++ +    LQ+                        
Sbjct: 297 ADKSELHHTLKNLSLKLDDLSTCNDLIAKHGAALQRSL---------------------- 334

Query: 333 DDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIE 392
                T  DG  + S +G K K+                 A  F+ T+  ++      +E
Sbjct: 335 -----TELDGLKIPSESGEKLKVVNE-------------RATLFRITSNAMINACRDFLE 376

Query: 393 LMVKREDSWQKRLDKETEKKRRTEEAYKNAMTELKKKSHFGGPDYEEGPNSLINEEEFFD 452
           L       WQ+ L  E E++   EE     + +L K+ +     +   P    N  + F 
Sbjct: 377 LAEIHSRKWQRALQYEQEQRVHLEE----TIEQLAKQHNSLERAFHSAPGRPANPSKSFI 432

Query: 453 AVEAALDRQDKIEEQSQSEKVRLHWPTSLPSGDAFSSVGTH-RFVQKPYSRSSSMSSIDL 511
                  + +  EE   +E     +  ++    +F +V T  +   +    S+  SS+D 
Sbjct: 433 EGSLLTPKGEDSEEDEDTE-----YFDAMEDSTSFITVITEAKEDSRKAEGSTGTSSVDW 487

Query: 512 VSASDD------VHRFSSQVEEMVQ--NHMTYSL 537
            SA +       V + SS+V+  V+  N   YSL
Sbjct: 488 SSADNVLDGASLVPKGSSKVKRRVRIPNKPNYSL 521


>gi|20070331 oxysterol binding protein-like 9 isoform e [Homo
           sapiens]
          Length = 736

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 62/175 (35%), Positives = 84/175 (48%), Gaps = 28/175 (16%)

Query: 156 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 212
           G LSKWTN + GWQ RW VL  NA  LSYY S+D+   G R G + L  AVI   D D+ 
Sbjct: 7   GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66

Query: 213 RFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYS 272
            F I+V+   ++ +A+D D R++WI A+E          E+ LR    +  L SG     
Sbjct: 67  TFTITVDQKTFHFQARDADEREKWIHALE----------ETILRHTLQLQGLDSG----F 112

Query: 273 ATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKV 327
             S   F K      KL E + +  IL  Q+         C     K++ QR K+
Sbjct: 113 VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDEQRKKI 156


>gi|22547173 oxysterol binding protein-like 9 isoform d [Homo
           sapiens]
          Length = 723

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 62/175 (35%), Positives = 84/175 (48%), Gaps = 28/175 (16%)

Query: 156 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 212
           G LSKWTN + GWQ RW VL  NA  LSYY S+D+   G R G + L  AVI   D D+ 
Sbjct: 7   GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66

Query: 213 RFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYS 272
            F I+V+   ++ +A+D D R++WI A+E          E+ LR    +  L SG     
Sbjct: 67  TFTITVDQKTFHFQARDADEREKWIHALE----------ETILRHTLQLQGLDSG----F 112

Query: 273 ATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKV 327
             S   F K      KL E + +  IL  Q+         C     K++ QR K+
Sbjct: 113 VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDEQRKKI 156


>gi|14249174 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 8 [Homo
           sapiens]
          Length = 440

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 48/153 (31%), Positives = 74/153 (48%), Gaps = 27/153 (17%)

Query: 156 GVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFD 215
           GVL KWTNY+ GWQ RW +L    LSYY S ++   GC+GSI ++   I  H  D  R D
Sbjct: 3   GVLYKWTNYLSGWQPRWFLLCGGILSYYDSPEDAWKGCKGSIQMAVCEIQVHSVDNTRMD 62

Query: 216 ISV-NDSVWYLRAQDPDHRQQWIDAIEQHK---TESGYGSESSLRRHGSMVSLVSGASGY 271
           + +  +  +YL+A+    RQ+W+ A+   K   T+S    E                   
Sbjct: 63  LIIPGEQYFYLKARSVAERQRWLVALGSAKACLTDSRTQKEKEFA--------------- 107

Query: 272 SATSTSSFKKGHSLREKLAEMETFRDILCRQVD 304
                   +   +L+ K++E+  + D+L +QVD
Sbjct: 108 --------ENTENLKTKMSELRLYCDLLVQQVD 132


>gi|22547176 oxysterol binding protein-like 9 isoform f [Homo
           sapiens]
          Length = 746

 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 61/185 (32%), Positives = 86/185 (46%), Gaps = 25/185 (13%)

Query: 156 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCR-GSICLSKAVITPHDFDEC 212
           G LSKWTN + GWQ RW VL  NA  LSYY S+D+   G R G + L  AVI   D D+ 
Sbjct: 7   GPLSKWTNVMKGWQYRWFVLDYNAGLLSYYTSKDKMMRGSRRGCVRLRGAVIGIDDEDDS 66

Query: 213 RFDISVNDSVWYLRAQDPDHRQQWIDAIE----------QHKTESGYGSESSLRRHGSMV 262
            F I+V+   ++ +A+D D R++WI A+E          Q  T   +   S +       
Sbjct: 67  TFTITVDQKTFHFQARDADEREKWIHALEETILRHTLQLQISTTLAFFQSSGISPVLEFS 126

Query: 263 SLVSGASGYSATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDEL 322
            ++   SG+   S   F K      KL E + +  IL  Q+         C     K++ 
Sbjct: 127 KIIGLDSGF-VPSVQDFDK------KLTEADAYLQILIEQLKLFDDKLQNC-----KEDE 174

Query: 323 QRDKV 327
           QR K+
Sbjct: 175 QRKKI 179


>gi|19923592 oxysterol binding protein-like 11 [Homo sapiens]
          Length = 747

 Score = 66.6 bits (161), Expect = 8e-11
 Identities = 49/146 (33%), Positives = 71/146 (48%), Gaps = 10/146 (6%)

Query: 156 GVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGCRGSICLSKAVITPHDFDECR 213
           G L K+TN + GWQ R+ VL N A  L Y+ +E       RG++ L+ AVI+P D D   
Sbjct: 63  GYLMKYTNLVTGWQYRFFVLNNEAGLLEYFVNEQSRNQKPRGTLQLAGAVISPSDEDSHT 122

Query: 214 FDISVNDSVWY-LRAQDPDHRQQWIDAIE---QHKTES-GYGSESSLRRHGSMVSLVSGA 268
           F ++      Y LRA D   RQ W+  ++   QH TE+ G  +     R  S+ S  +  
Sbjct: 123 FTVNAASGEQYKLRATDAKERQHWVSRLQICTQHHTEAIGKNNPPLKSRSFSLASSSNSP 182

Query: 269 SGY---SATSTSSFKKGHSLREKLAE 291
                 S  + S F  GHS  + L++
Sbjct: 183 ISQRRPSQNAISFFNVGHSKLQSLSK 208


>gi|19923812 oxysterol-binding protein-like protein 10 [Homo
           sapiens]
          Length = 764

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 58/165 (35%), Positives = 77/165 (46%), Gaps = 17/165 (10%)

Query: 77  GGRTSSLLLLPPTPERALFASPSPDPSPRGLGASS-GAAEGAGAGLLLGCRASMSDNQSW 135
           GG  SS      +  RA  A  SP  S  G G SS  AA G G G   G R+S     + 
Sbjct: 12  GGSNSS----SRSSSRATSAGSSPSCSLAGRGVSSRSAAAGLGGG---GSRSSPGSVAAS 64

Query: 136 NSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNA--LSYYKSEDETEYGC 193
            S G     E    P +E  GVLSK+TN + GWQ+R+ VL   A  L Y+ +E       
Sbjct: 65  PSGGGGRRRE----PALE--GVLSKYTNLLQGWQNRYFVLDFEAGILQYFVNEQSKHQKP 118

Query: 194 RGSICLSKAVITPHDFDECRFDI-SVNDSVWYLRAQDPDHRQQWI 237
           RG + LS A+++  D       + S N  ++ LRA D   +Q W+
Sbjct: 119 RGVLSLSGAIVSLSDEAPHMLVVYSANGEMFKLRAADAKEKQFWV 163


>gi|19718741 oxysterol-binding protein-like 1A isoform B [Homo
           sapiens]
          Length = 950

 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 80/351 (22%), Positives = 134/351 (38%), Gaps = 89/351 (25%)

Query: 167 GWQDRWVVLKNNALSYYKSEDETEYGCRGSIC--LSKAVITPHDFDECRFDIS-VNDSVW 223
           GW+  WVVL++  LS+Y+ + +  +      C  L++AV T    D C F I   +D++ 
Sbjct: 250 GWRLFWVVLEHGVLSWYRKQPDAVHNIYRQGCKHLTQAVCTVKSTDSCLFFIKCFDDTIH 309

Query: 224 YLRAQD---PDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGYSATSTSSFK 280
             R         R+ W++AIE+H   S +               VS A            
Sbjct: 310 GFRVPKNSLQQSREDWLEAIEEHSAYSTHYCSQDQLTDEEEEDTVSAA------------ 357

Query: 281 KGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDDEDDFPTTRS 340
               L++ L + ++ +  L R++    K    C  A                        
Sbjct: 358 ---DLKKSLEKAQSCQQRLDREISNFLKMIKECDMA------------------------ 390

Query: 341 DGDFLHSTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCIELMVKREDS 400
                      KE L     P  +  ++   EA      +      L+ C+ L  K+E  
Sbjct: 391 -----------KEML-----PSFLQKVEVVSEA------SRETCVALTDCLNLFTKQEGV 428

Query: 401 WQKRLDKETEKKRRTEEAYKNAMT---ELKKKSHFGGPDYEEGPNSLINEEEFFDAV--- 454
              +L++E EK +   EA +   T   EL++    G P     P S+++E+EF+DA+   
Sbjct: 429 RNFKLEQEQEKNKILSEALETLATEHHELEQSLVKGSP-----PASILSEDEFYDALSDS 483

Query: 455 --EAALDRQDKI-----EEQSQ---SEKVRLHWPTSLPSGDAFSS-VGTHR 494
             E +L R + +     EE+ +   S K R+        GDA S+ +  HR
Sbjct: 484 ESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHR 534


>gi|55741447 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 1 [Homo sapiens]
          Length = 1364

 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 42/182 (23%), Positives = 71/182 (39%), Gaps = 4/182 (2%)

Query: 79  RTSSLLLLPPTPERALFASPSPDPSPRGLGASSGAAEGAGA----GLLLGCRASMSDNQS 134
           + S  + +P +  R      SP    RG+  SS ++EG  A       L    S  +++ 
Sbjct: 502 QASFRISVPSSESRKTSGLGSPRAIKRGVSMSSLSSEGDYAIPPDACSLDSDYSEPEHKL 561

Query: 135 WNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCR 194
             +S    D     G  +E+ G L K  + +  W+ RW VL+   + YYKS  +     +
Sbjct: 562 QRTSSYSTDGLGLGGESLEKSGYLLKMGSQVKTWKRRWFVLRQGQIMYYKSPSDVIRKPQ 621

Query: 195 GSICLSKAVITPHDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESS 254
           G + L+             F +      +YL A  P   ++WI  ++        G  + 
Sbjct: 622 GQVDLNSRCQIVRGEGSQTFQLISEKKTYYLTADSPSLLEEWIRVLQSLLKVQATGPPAL 681

Query: 255 LR 256
           LR
Sbjct: 682 LR 683


>gi|217416392 pleckstrin homology domain containing, family H (with
           MyTH4 domain) member 2 [Homo sapiens]
          Length = 1493

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 41/150 (27%), Positives = 67/150 (44%), Gaps = 12/150 (8%)

Query: 99  SPDPSPRGLGASSGAAEGAGAGLLLGCRASMSDNQSWNSSGSEEDPETESGP-------P 151
           SP    RG+  SS A+E   A   +   A  +D +   S   ++ P+T S         P
Sbjct: 649 SPRAMKRGVSLSSVASESDYA---IPPDAYSTDTEY--SQPEQKLPKTCSSSSDNGKNEP 703

Query: 152 VERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDE 211
           +E+ G L K +  +  W+ RW VLK   L YYKS  +     +G I LS +       ++
Sbjct: 704 LEKSGYLLKMSGKVKSWKRRWFVLKGGELLYYKSPSDVIRKPQGHIELSASCSILRGDNK 763

Query: 212 CRFDISVNDSVWYLRAQDPDHRQQWIDAIE 241
               ++     +YL A  P+  ++WI  ++
Sbjct: 764 QTVQLTTEKHTYYLTADSPNILEEWIKVLQ 793


>gi|93102364 SWAP-70 protein [Homo sapiens]
          Length = 585

 Score = 50.8 bits (120), Expect = 5e-06
 Identities = 72/345 (20%), Positives = 138/345 (40%), Gaps = 50/345 (14%)

Query: 156 GVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSK----AVITPHDFDE 211
           G + K  +    W +RW VLK N +SYY SED  +   +G I L +      +   D  +
Sbjct: 215 GYMMKKGHRRKNWTERWFVLKPNIISYYVSEDLKDK--KGDILLDENCCVESLPDKDGKK 272

Query: 212 CRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHKTESGYGSESSLRRHGSMVSLVSGASGY 271
           C F +   D  + + A D   +Q+WI AI          S   L + GS           
Sbjct: 273 CLFLVKCFDKTFEISASDKKKKQEWIQAIH---------STIHLLKLGSPPPHKEARQRR 323

Query: 272 SATSTSSFKKGHSLREKLAEMETFRDILCRQVDTLQKYFDACADAVSKDELQRDKVVEDD 331
                    +   L  ++ E++   +   ++++ ++K  +  A   +++E +R +   + 
Sbjct: 324 KELRKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVEL 383

Query: 332 EDDFPTTRSDGDFLHSTNGNKEKLFPHVTPKGINGIDFKGEAITFKATTAGILATLSHCI 391
           +  F           ST   +EKL      + +       ++   +     +       +
Sbjct: 384 QARF-----------STELEREKLIRQQMEEQV-----AQKSSELEQYLQRVRELEDMYL 427

Query: 392 ELMVKREDSWQKRLDKETEKKRRT----EEAYKNAMTE---LKKKSHFGGPDYE--EGPN 442
           +L    ED  Q R D+ET +K +     EE+ K A  E   L+++      + E  E  N
Sbjct: 428 KLQEALEDERQARQDEETVRKLQARLLEEESSKRAELEKWHLEQQQAIQTTEAEKQELEN 487

Query: 443 SLINEEEFFDAVEAALDRQDKIE-------EQSQSEKVRLHWPTS 480
             + +E+   A++ A+++ +++E       EQ +  K +L   T+
Sbjct: 488 QRVLKEQ---ALQEAMEQLEQLELERKQALEQYEEVKKKLEMATN 529


>gi|29788755 SET binding factor 2 [Homo sapiens]
          Length = 1849

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 14/98 (14%)

Query: 156  GVLSKWTNYIHGWQDRWVVLK--NNALSYYKSEDETEYGCRGSICLSKA-VITP------ 206
            G L K    + GW+ RW VL    + L YY S ++T   C+G I L++  ++ P      
Sbjct: 1748 GTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTS--CKGHIDLAEVEMVIPAGPSMG 1805

Query: 207  ---HDFDECRFDISVNDSVWYLRAQDPDHRQQWIDAIE 241
               H  D+  FD+  +  V+   AQD    QQW+D I+
Sbjct: 1806 APKHTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDKIQ 1843


>gi|111154092 Rho GTPase activating protein 24 isoform 1 [Homo
           sapiens]
          Length = 748

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 16/121 (13%)

Query: 136 NSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRG 195
           N+  +E   + +      +CG L K   ++  W  RW VLK + L Y+K EDET+    G
Sbjct: 4   NNDSTENPQQGQGRQNAIKCGWLRKQGGFVKTWHTRWFVLKGDQLYYFKDEDETK--PLG 61

Query: 196 SICLSKAVITPHDFDE--------------CRFDISVNDSVWYLRAQDPDHRQQWIDAIE 241
           +I L    ++ H  +E               R  ++ N   + L A   +  + W+ +I 
Sbjct: 62  TIFLPGNKVSEHPCNEENPGKFLFEVVPGGDRDRMTANHESYLLMASTQNDMEDWVKSIR 121

Query: 242 Q 242
           +
Sbjct: 122 R 122


>gi|116812600 START domain containing 10 [Homo sapiens]
          Length = 291

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 46/194 (23%), Positives = 76/194 (39%), Gaps = 19/194 (9%)

Query: 543 DANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETT 602
           +  W L      + V+ + VE +   L  +K       V    + +   +++ R  W++ 
Sbjct: 40  EVGWNLTYSRAGVSVWVQAVEMDR-TLHKIKCRMECCDVPAETLYDVLHDIEYRKKWDSN 98

Query: 603 IENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVD 662
           +     +  L  NA + Y + +   P   RDV+ L     + A        +I+ N+SV 
Sbjct: 99  VIETFDIARLTVNADVGYYSWRCPKPLKNRDVITLRSWLPMGA-------DYIIMNYSVK 151

Query: 663 HDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVL 722
           H   P     VRA           VS   G    S     C ITY+A V+P G  P  V+
Sbjct: 152 HPKYPPRKDLVRA-----------VSIQTGYLIQSTGPKSCVITYLAQVDPKGSLPKWVV 200

Query: 723 RAVAKREYPKFLKR 736
              ++   PK +K+
Sbjct: 201 NKSSQFLAPKAMKK 214


>gi|7662310 FERM, RhoGEF and pleckstrin domain protein 2 [Homo
            sapiens]
          Length = 1054

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 47/205 (22%), Positives = 81/205 (39%), Gaps = 24/205 (11%)

Query: 56   RLPSPLVLLPRSARCQARRRRGGRTSSLLLLPPTPERALFASPSPDPSPRGLGASS---- 111
            RL     +L  ++  QA +  GG T+     P  P R +   P   P+   L   S    
Sbjct: 837  RLEKEKWMLDLNSAIQAAKS-GGDTA-----PALPGRTVCTRPPRSPNEVSLEQESEDDA 890

Query: 112  ----GAAEGAGAGLLLGCRASMSDNQSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHG 167
                 + EG G       RA+ + +  W  + S    +  +    +  G L +     HG
Sbjct: 891  RGVRSSLEGHGQH-----RANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSHG 945

Query: 168  WQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFD----ECRFDISVNDSVW 223
            WQ  WVV  N  L +YK+  + +Y       L  +V  P + D    +  F +     V+
Sbjct: 946  WQKLWVVFTNFCLFFYKTHQD-DYPLASLPLLGYSVSIPREADGIHKDYVFKLQFKSHVY 1004

Query: 224  YLRAQDPDHRQQWIDAIEQHKTESG 248
            + RA+     ++W++ I+   + +G
Sbjct: 1005 FFRAESKYTFERWMEVIQGASSSAG 1029


>gi|34013590 Rho GTPase activating protein 2 [Homo sapiens]
          Length = 698

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 18/108 (16%)

Query: 151 PVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVIT----- 205
           PV + G L K  + +  WQ RW VL+ + L YYK +DE +   +G I L    +T     
Sbjct: 37  PVLKAGWLKKQRSIMKNWQQRWFVLRGDQLFYYKDKDEIK--PQGFISLQGTQVTELPPG 94

Query: 206 PHDFDECRFDIS-----------VNDSVWYLRAQDPDHRQQWIDAIEQ 242
           P D  +  F+IS            N     L A      + W+ AI +
Sbjct: 95  PEDPGKHLFEISPGGAGEREKVPANPEALLLMASSQRDMEDWVQAIRR 142


>gi|239735519 SET binding factor 1 [Homo sapiens]
          Length = 1893

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 50/181 (27%), Positives = 71/181 (39%), Gaps = 25/181 (13%)

Query: 76   RGGRTSSLLLLPPTPERAL--FASPSPDPSPRGLGASSGAAEGAG-AGLLLGCRASMSDN 132
            RG  +S L+   P   R+L  +    P  S   L   S  + G+  +G     R S S  
Sbjct: 1717 RGTPSSLLVSTAPHHRRSLGVYLQEGPVGSTLSLSLDSDQSSGSTTSGSRQAARRSTSTL 1776

Query: 133  QSWNSSGSEEDPETESGPPVERCGVLSKWTNYIHGWQDRWVVLKN--NALSYYKSEDETE 190
             S   +   E+   E        G L K   ++  W+ RW VL    + L YY    +TE
Sbjct: 1777 YSQFQTAESENRSYE--------GTLYKKGAFMKPWKARWFVLDKTKHQLRYYDHRVDTE 1828

Query: 191  YGCRGSICLSKAVIT---------PHDFDE-CRFDISVNDSVWYLRAQDPDHRQQWIDAI 240
              C+G I L++             P   DE   FD+     V+   AQD    QQW+D I
Sbjct: 1829 --CKGVIDLAEVEAVAPGTPTMGAPKTVDEKAFFDVKTTRRVYNFCAQDVPSAQQWVDRI 1886

Query: 241  E 241
            +
Sbjct: 1887 Q 1887


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein
           [Homo sapiens]
          Length = 3969

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 27/73 (36%), Positives = 36/73 (49%), Gaps = 1/73 (1%)

Query: 84  LLLPPTPERALFASPSPDPSPRGLGASSGAAEGAGAGLLLGCRASMSDNQSWNSSGSEED 143
           LLLPP P       P   PSP  + A++ AA  +GAG+  G  A+ + + S  SS S   
Sbjct: 38  LLLPPGPPVG-GGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSS 96

Query: 144 PETESGPPVERCG 156
               SGP + R G
Sbjct: 97  SSASSGPALLRVG 109



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 33/140 (23%), Positives = 55/140 (39%), Gaps = 1/140 (0%)

Query: 11  SPFSAPPAFLPVVTRESRRGLSSGGSAGRNAGVTATAAAADGWKGRLPSPLVLLPRSARC 70
           SP    P F P           +  S   +AG +++  +    K ++ SP+   PRS   
Sbjct: 694 SPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPS- 752

Query: 71  QARRRRGGRTSSLLLLPPTPERALFASPSPDPSPRGLGASSGAAEGAGAGLLLGCRASMS 130
            + R R GR SS  L P TP  ++ +S S   SP    A +         L     ++  
Sbjct: 753 HSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESAEK 812

Query: 131 DNQSWNSSGSEEDPETESGP 150
           + +    + +  +P + S P
Sbjct: 813 NQRPRKQTSAPAEPFSSSSP 832


>gi|154146216 pleckstrin homology domain containing, family A
           (phosphoinositide binding specific) member 2 [Homo
           sapiens]
          Length = 425

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 35/136 (25%), Positives = 57/136 (41%), Gaps = 20/136 (14%)

Query: 148 SGPPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPH 207
           +GPP+ + G   K  N    W+ R+  L +  + Y+K E + E          K V+  H
Sbjct: 195 TGPPLIKSGYCVKQGNVRKSWKRRFFALDDFTICYFKCEQDRE---PLRTIFLKDVLKTH 251

Query: 208 D---------FDECRFDISVNDSVWYLRAQDPDHRQQWI-------DAIEQHKTESGYGS 251
           +           +  F+I  +   +Y++A  P+    WI        A++ H  E+ +  
Sbjct: 252 ECLVKSGDLLMRDNLFEIITSSRTFYVQADSPEDMHSWIKEIGAAVQALKCHPRETSFSR 311

Query: 252 ESSLRRHGSMVSLVSG 267
             SL R GS  SL SG
Sbjct: 312 SISLTRPGSS-SLSSG 326


>gi|156151415 phosphatidylcholine transfer protein isoform 1 [Homo
           sapiens]
          Length = 214

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 47/193 (24%), Positives = 78/193 (40%), Gaps = 20/193 (10%)

Query: 544 ANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWETTI 603
           A+WQL+VE   + +YR   ++ G  L   K    ++  +   + + + + D R  W+  +
Sbjct: 28  ADWQLLVETSGISIYRLLDKKTG--LYEYKVFGVLEDCSPTLLADIYMDSDYRKQWDQYV 85

Query: 604 ENFHVVETLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCNFSVDH 663
           +  +  E   +   ++Y   K  +P S RD +YL   R +      D E   +       
Sbjct: 86  KELY--EQECNGETVVYWEVKYPFPMSNRDYVYLRQRRDL------DMEGRKIHVILARS 137

Query: 664 DSAP-LNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAPASVL 722
            S P L  R     I V    Q+L    +G +         K+      NPGG  P+ ++
Sbjct: 138 TSMPQLGER--SGVIRVKQYKQSLAIESDGKKG-------SKVFMYYFDNPGGQIPSWLI 188

Query: 723 RAVAKREYPKFLK 735
              AK   P FLK
Sbjct: 189 NWAAKNGVPNFLK 201


>gi|151301035 START domain containing 7 [Homo sapiens]
          Length = 370

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 43/198 (21%), Positives = 87/198 (43%), Gaps = 18/198 (9%)

Query: 541 GGDANWQLVVEEGEMKVYRREVEENGIVLDPLKATHAVKGVTGHEVCNYFWNVDVRNDWE 600
           G +  W++V+++   K++RR +   G  L   +       VT  +  N   + + R  W+
Sbjct: 136 GKEQRWEMVMDKKHFKLWRRPI--TGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWD 193

Query: 601 TTIENFHVVE--TLADNAIIIYQTHKRVWPASQRDVLYLSVIRKIPALTENDPETWIVCN 658
             +    V+E   ++ + ++ + TH   +P   RD +Y   +R+     EN+    ++ +
Sbjct: 194 ALVIKLEVIERDVVSGSEVLHWVTH-FPYPMYSRDYVY---VRRYSVDQENN--MMVLVS 247

Query: 659 FSVDHDSAPLNNRCVRAKINVAMICQTLVSPPEGNQEISRDNILCKITYVANVNPGGWAP 718
            +V+H S P +   VR +   +   Q ++ P +   E   D +L   TY  + NP    P
Sbjct: 248 RAVEHPSVPESPEFVRVR---SYESQMVIRPHKSFDENGFDYLL---TY--SDNPQTVFP 299

Query: 719 ASVLRAVAKREYPKFLKR 736
              +  +     P FL++
Sbjct: 300 RYCVSWMVSSGMPDFLEK 317


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 20/75 (26%), Positives = 38/75 (50%), Gaps = 1/75 (1%)

Query: 168  WQDRWVVLKNNALSYYKSEDETEYGCRGSICLSKAVITPHDFDECRFDISVNDSVWYLRA 227
            W+ RW VL+ + L Y++++ E +      +  +K +I  +   E   DI + D  ++L A
Sbjct: 1234 WKKRWFVLRQSKLMYFENDSEEKLKGTVEVRTAKEII-DNTTKENGIDIIMADRTFHLIA 1292

Query: 228  QDPDHRQQWIDAIEQ 242
            + P+   QW   + Q
Sbjct: 1293 ESPEDASQWFSVLSQ 1307


>gi|21735584 oxysterol-binding protein-like protein 3 isoform d
           [Homo sapiens]
          Length = 820

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 22/96 (22%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 150 PPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETE-YGCRGSICLSKAVITPHD 208
           PPV++  +L K    + GW  R+  L    L Y KS+ + E     G I +  +V++   
Sbjct: 51  PPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKK 110

Query: 209 FDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHK 244
             +C  D+   + +++L+ +  +   +W+  +  H+
Sbjct: 111 SSKC-IDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145


>gi|21735582 oxysterol-binding protein-like protein 3 isoform c
           [Homo sapiens]
          Length = 851

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 22/96 (22%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 150 PPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETE-YGCRGSICLSKAVITPHD 208
           PPV++  +L K    + GW  R+  L    L Y KS+ + E     G I +  +V++   
Sbjct: 51  PPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKK 110

Query: 209 FDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHK 244
             +C  D+   + +++L+ +  +   +W+  +  H+
Sbjct: 111 SSKC-IDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145


>gi|21735580 oxysterol-binding protein-like protein 3 isoform b
           [Homo sapiens]
          Length = 856

 Score = 41.2 bits (95), Expect = 0.004
 Identities = 22/96 (22%), Positives = 46/96 (47%), Gaps = 2/96 (2%)

Query: 150 PPVERCGVLSKWTNYIHGWQDRWVVLKNNALSYYKSEDETE-YGCRGSICLSKAVITPHD 208
           PPV++  +L K    + GW  R+  L    L Y KS+ + E     G I +  +V++   
Sbjct: 51  PPVQKGFLLKKRKWPLKGWHKRFFYLDKGILKYAKSQTDIEREKLHGCIDVGLSVMSVKK 110

Query: 209 FDECRFDISVNDSVWYLRAQDPDHRQQWIDAIEQHK 244
             +C  D+   + +++L+ +  +   +W+  +  H+
Sbjct: 111 SSKC-IDLDTEEHIYHLKVKSEEVFDEWVSKLRHHR 145


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,615,061
Number of Sequences: 37866
Number of extensions: 1558135
Number of successful extensions: 8524
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 208
Number of HSP's that attempted gapping in prelim test: 8128
Number of HSP's gapped (non-prelim): 534
length of query: 752
length of database: 18,247,518
effective HSP length: 110
effective length of query: 642
effective length of database: 14,082,258
effective search space: 9040809636
effective search space used: 9040809636
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.