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Search of human proteins with 194018539
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194018539 myosin binding protein H-like [Homo sapiens]
(354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194018539 myosin binding protein H-like [Homo sapiens] 727 0.0
gi|55956914 myosin binding protein H [Homo sapiens] 473 e-133
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ... 375 e-104
gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ... 375 e-104
gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ... 375 e-104
gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ... 375 e-104
gi|148596957 myosin binding protein C, cardiac [Homo sapiens] 344 8e-95
gi|133908641 myosin binding protein C, fast type [Homo sapiens] 342 4e-94
gi|148839296 immunoglobulin-like and fibronectin type III domain... 134 9e-32
gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens] 127 1e-29
gi|110349719 titin isoform N2-A [Homo sapiens] 113 2e-25
gi|110349717 titin isoform novex-2 [Homo sapiens] 113 2e-25
gi|110349713 titin isoform novex-1 [Homo sapiens] 113 2e-25
gi|110349715 titin isoform N2-B [Homo sapiens] 113 2e-25
gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens] 64 3e-10
gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens] 64 3e-10
gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens] 64 3e-10
gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens] 64 3e-10
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens] 63 5e-10
gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens] 63 5e-10
gi|140560917 myomesin 1 isoform b [Homo sapiens] 62 8e-10
gi|140560919 myomesin 1 isoform a [Homo sapiens] 62 8e-10
gi|155969693 myomesin family, member 3 [Homo sapiens] 61 1e-09
gi|156104903 myomesin 2 [Homo sapiens] 61 2e-09
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact... 60 2e-09
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac... 60 2e-09
gi|75709184 contactin 3 [Homo sapiens] 59 9e-09
gi|118572606 hemicentin 1 [Homo sapiens] 58 1e-08
gi|15147240 brother of CDO [Homo sapiens] 56 4e-08
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 55 7e-08
>gi|194018539 myosin binding protein H-like [Homo sapiens]
Length = 354
Score = 727 bits (1877), Expect = 0.0
Identities = 354/354 (100%), Positives = 354/354 (100%)
Query: 1 MEAATAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALR 60
MEAATAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALR
Sbjct: 1 MEAATAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALR 60
Query: 61 QTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADS 120
QTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADS
Sbjct: 61 QTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADS 120
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY 180
GRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY
Sbjct: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY 180
Query: 181 TVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHI 240
TVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHI
Sbjct: 181 TVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHI 240
Query: 241 QKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMD 300
QKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMD
Sbjct: 241 QKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMD 300
Query: 301 IQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
IQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN
Sbjct: 301 IQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
>gi|55956914 myosin binding protein H [Homo sapiens]
Length = 477
Score = 473 bits (1216), Expect = e-133
Identities = 235/349 (67%), Positives = 276/349 (79%), Gaps = 9/349 (2%)
Query: 5 TAPEVAAGSK--LKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQT 62
T +A G K L+V S A A PP A P + E PKI +PR LRQT
Sbjct: 131 TVRNLALGDKFLLRVSAVSSAGAGPP-------AMLDQPIHIRENIEAPKIRVPRHLRQT 183
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
YIR+VG+TVNL IPFQGKPKPQA WTH+G ALD++RVS+R G+QDSILFIR AQR+DSGR
Sbjct: 184 YIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGR 243
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Y+L V++ LEA A IDILVIE+PGPP SI+L+DVWG +A L+WTPPQDTGNT LLGY V
Sbjct: 244 YELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMV 303
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQK 242
QKAD K+G WFTVLE YH T+C +SDLIIGNSY+FRVF+EN CGLS +A +T +LAHIQK
Sbjct: 304 QKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQK 363
Query: 243 AATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ 302
A K KGF +RDFSEAP FTQPLAD T+ GY+TQLFC VRASP+PKIIW+KNKM+IQ
Sbjct: 364 ADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQ 423
Query: 303 GNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
GNPKYRAL+ G+C+LEIRKP PFD G+YTCKA+N LGEASVDCR++VK
Sbjct: 424 GNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVK 472
Score = 43.5 bits (101), Expect = 3e-04
Identities = 40/156 (25%), Positives = 57/156 (36%), Gaps = 19/156 (12%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
P P + L DV S T+ W PP+ G L GY ++ + W V T
Sbjct: 71 PSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQ 130
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
V +L +G+ + RV A + G A + + HI R+ EAPK
Sbjct: 131 TVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPI-HI--------------RENIEAPKIR 175
Query: 265 QPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKN 297
P T G L + P+P+ W N
Sbjct: 176 VPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHN 211
>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
sapiens]
Length = 1123
Score = 375 bits (963), Expect = e-104
Identities = 172/322 (53%), Positives = 232/322 (72%), Gaps = 4/322 (1%)
Query: 35 GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
GA P P L+ I E PKI +PR L+QTYIR+VG+ VNL+IPFQGKP+P+ W D
Sbjct: 799 GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 858
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
G +D ++++RN E D+I+FIR+A+R+ SG+Y L+V++ TA+IDI +I+RPGPPQ
Sbjct: 859 GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 918
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
+K+ DVWG + L WTPP+D GN A+ GYT+QKAD KS WFTV+EHYHRTS +++L+
Sbjct: 919 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 978
Query: 211 IGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC 270
IGN Y FRVF+EN CGLSE A +T + A I + +YK + DFSEAP FTQPL +
Sbjct: 979 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1038
Query: 271 TTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
+ GYN L C VR +P+PKI W+KNK+ I +P+YR ++ G+C+LEIRKP P+DGG
Sbjct: 1039 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1098
Query: 331 YTCKAVNPLGEASVDCRVDVKV 352
Y CKAVN LG ++C+++VKV
Sbjct: 1099 YCCKAVNDLGTVEIECKLEVKV 1120
Score = 81.3 bits (199), Expect = 1e-15
Identities = 48/165 (29%), Positives = 84/165 (50%), Gaps = 3/165 (1%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
G+ + L IP G+P P+A+W+ A+ + R+ + S L I A+R DSG Y +
Sbjct: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
Query: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
++ EA A+I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
Query: 186 DTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+S W + + T+ +I G +Y R+FA N G+S+
Sbjct: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
Score = 37.0 bits (84), Expect = 0.027
Identities = 36/161 (22%), Positives = 56/161 (34%), Gaps = 19/161 (11%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP + + V + T+ W PP G L GY ++ + W + +T +
Sbjct: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 779
Query: 207 SDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQP 266
+ L RV A N G SE Y ++ ++ E PK P
Sbjct: 780 TGLPTDAKIFVRVKAVNAAGASEPK---------------YYSQPILVKEIIEPPKIRIP 824
Query: 267 LADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGN 304
T G L + PRP++ W K+ +I N
Sbjct: 825 RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 865
Score = 34.7 bits (78), Expect = 0.13
Identities = 57/260 (21%), Positives = 93/260 (35%), Gaps = 38/260 (14%)
Query: 98 RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDI--LVIERPGPPQSIKLV 155
R +R + IL I A +AD+ Y + G A ++D+ L I P Q++ L
Sbjct: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
Query: 156 DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSY 215
+ P G G VQ++D L+ H+ + L+I N+
Sbjct: 448 KEICLKCEISENIP---GKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANA- 493
Query: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC----T 271
+T D A Y A+ + PK D T
Sbjct: 494 -----------------LTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
Query: 272 TVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
+ G +L + P PK +W + +K ++G+ + R ++ +L I D G+
Sbjct: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
Query: 331 YTCKAVNPLGEASVDCRVDV 350
Y N GEA +V V
Sbjct: 597 YHINLKNEAGEAHASIKVKV 616
>gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
sapiens]
Length = 1141
Score = 375 bits (963), Expect = e-104
Identities = 172/322 (53%), Positives = 232/322 (72%), Gaps = 4/322 (1%)
Query: 35 GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
GA P P L+ I E PKI +PR L+QTYIR+VG+ VNL+IPFQGKP+P+ W D
Sbjct: 817 GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 876
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
G +D ++++RN E D+I+FIR+A+R+ SG+Y L+V++ TA+IDI +I+RPGPPQ
Sbjct: 877 GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 936
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
+K+ DVWG + L WTPP+D GN A+ GYT+QKAD KS WFTV+EHYHRTS +++L+
Sbjct: 937 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 996
Query: 211 IGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC 270
IGN Y FRVF+EN CGLSE A +T + A I + +YK + DFSEAP FTQPL +
Sbjct: 997 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1056
Query: 271 TTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
+ GYN L C VR +P+PKI W+KNK+ I +P+YR ++ G+C+LEIRKP P+DGG
Sbjct: 1057 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1116
Query: 331 YTCKAVNPLGEASVDCRVDVKV 352
Y CKAVN LG ++C+++VKV
Sbjct: 1117 YCCKAVNDLGTVEIECKLEVKV 1138
Score = 81.3 bits (199), Expect = 1e-15
Identities = 48/165 (29%), Positives = 84/165 (50%), Gaps = 3/165 (1%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
G+ + L IP G+P P+A+W+ A+ + R+ + S L I A+R DSG Y +
Sbjct: 540 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 599
Query: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
++ EA A+I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 600 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 659
Query: 186 DTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+S W + + T+ +I G +Y R+FA N G+S+
Sbjct: 660 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 704
Score = 34.7 bits (78), Expect = 0.13
Identities = 57/260 (21%), Positives = 93/260 (35%), Gaps = 38/260 (14%)
Query: 98 RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDI--LVIERPGPPQSIKLV 155
R +R + IL I A +AD+ Y + G A ++D+ L I P Q++ L
Sbjct: 388 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 447
Query: 156 DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSY 215
+ P G G VQ++D L+ H+ + L+I N+
Sbjct: 448 KEICLKCEISENIP---GKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANA- 493
Query: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC----T 271
+T D A Y A+ + PK D T
Sbjct: 494 -----------------LTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 536
Query: 272 TVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
+ G +L + P PK +W + +K ++G+ + R ++ +L I D G+
Sbjct: 537 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 596
Query: 331 YTCKAVNPLGEASVDCRVDV 350
Y N GEA +V V
Sbjct: 597 YHINLKNEAGEAHASIKVKV 616
Score = 30.4 bits (67), Expect = 2.5
Identities = 36/164 (21%), Positives = 56/164 (34%), Gaps = 7/164 (4%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI-V 206
PP + + V + T+ W PP G L GY ++ S E+ +
Sbjct: 720 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPA 779
Query: 207 SDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAAT---VYKTKGFAQRDFSEAPKF 263
D I+ N GL A I + + A Y ++ ++ E PK
Sbjct: 780 EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 839
Query: 264 TQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGN 304
P T G L + PRP++ W K+ +I N
Sbjct: 840 RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 883
>gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
sapiens]
Length = 1148
Score = 375 bits (963), Expect = e-104
Identities = 172/322 (53%), Positives = 232/322 (72%), Gaps = 4/322 (1%)
Query: 35 GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
GA P P L+ I E PKI +PR L+QTYIR+VG+ VNL+IPFQGKP+P+ W D
Sbjct: 824 GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
G +D ++++RN E D+I+FIR+A+R+ SG+Y L+V++ TA+IDI +I+RPGPPQ
Sbjct: 884 GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
+K+ DVWG + L WTPP+D GN A+ GYT+QKAD KS WFTV+EHYHRTS +++L+
Sbjct: 944 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 1003
Query: 211 IGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC 270
IGN Y FRVF+EN CGLSE A +T + A I + +YK + DFSEAP FTQPL +
Sbjct: 1004 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1063
Query: 271 TTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
+ GYN L C VR +P+PKI W+KNK+ I +P+YR ++ G+C+LEIRKP P+DGG
Sbjct: 1064 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1123
Query: 331 YTCKAVNPLGEASVDCRVDVKV 352
Y CKAVN LG ++C+++VKV
Sbjct: 1124 YCCKAVNDLGTVEIECKLEVKV 1145
Score = 81.3 bits (199), Expect = 1e-15
Identities = 48/165 (29%), Positives = 84/165 (50%), Gaps = 3/165 (1%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
G+ + L IP G+P P+A+W+ A+ + R+ + S L I A+R DSG Y +
Sbjct: 565 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
Query: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
++ EA A+I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 625 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
Query: 186 DTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+S W + + T+ +I G +Y R+FA N G+S+
Sbjct: 685 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
Score = 37.0 bits (84), Expect = 0.027
Identities = 36/161 (22%), Positives = 56/161 (34%), Gaps = 19/161 (11%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP + + V + T+ W PP G L GY ++ + W + +T +
Sbjct: 745 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
Query: 207 SDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQP 266
+ L RV A N G SE Y ++ ++ E PK P
Sbjct: 805 TGLPTDAKIFVRVKAVNAAGASEPK---------------YYSQPILVKEIIEPPKIRIP 849
Query: 267 LADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGN 304
T G L + PRP++ W K+ +I N
Sbjct: 850 RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
Score = 34.7 bits (78), Expect = 0.13
Identities = 57/260 (21%), Positives = 93/260 (35%), Gaps = 38/260 (14%)
Query: 98 RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDI--LVIERPGPPQSIKLV 155
R +R + IL I A +AD+ Y + G A ++D+ L I P Q++ L
Sbjct: 413 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
Query: 156 DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSY 215
+ P G G VQ++D L+ H+ + L+I N+
Sbjct: 473 KEICLKCEISENIP---GKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANA- 518
Query: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC----T 271
+T D A Y A+ + PK D T
Sbjct: 519 -----------------LTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
Query: 272 TVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
+ G +L + P PK +W + +K ++G+ + R ++ +L I D G+
Sbjct: 562 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 621
Query: 331 YTCKAVNPLGEASVDCRVDV 350
Y N GEA +V V
Sbjct: 622 YHINLKNEAGEAHASIKVKV 641
>gi|45976288 myosin binding protein C, slow type isoform 1 [Homo
sapiens]
Length = 1171
Score = 375 bits (963), Expect = e-104
Identities = 172/322 (53%), Positives = 232/322 (72%), Gaps = 4/322 (1%)
Query: 35 GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
GA P P L+ I E PKI +PR L+QTYIR+VG+ VNL+IPFQGKP+P+ W D
Sbjct: 824 GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
G +D ++++RN E D+I+FIR+A+R+ SG+Y L+V++ TA+IDI +I+RPGPPQ
Sbjct: 884 GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
+K+ DVWG + L WTPP+D GN A+ GYT+QKAD KS WFTV+EHYHRTS +++L+
Sbjct: 944 IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 1003
Query: 211 IGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC 270
IGN Y FRVF+EN CGLSE A +T + A I + +YK + DFSEAP FTQPL +
Sbjct: 1004 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1063
Query: 271 TTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
+ GYN L C VR +P+PKI W+KNK+ I +P+YR ++ G+C+LEIRKP P+DGG
Sbjct: 1064 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1123
Query: 331 YTCKAVNPLGEASVDCRVDVKV 352
Y CKAVN LG ++C+++VKV
Sbjct: 1124 YCCKAVNDLGTVEIECKLEVKV 1145
Score = 81.3 bits (199), Expect = 1e-15
Identities = 48/165 (29%), Positives = 84/165 (50%), Gaps = 3/165 (1%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
G+ + L IP G+P P+A+W+ A+ + R+ + S L I A+R DSG Y +
Sbjct: 565 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
Query: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
++ EA A+I + V++ P PP + + +V + W PP G + +LGY +++
Sbjct: 625 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
Query: 186 DTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+S W + + T+ +I G +Y R+FA N G+S+
Sbjct: 685 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
Score = 37.0 bits (84), Expect = 0.027
Identities = 36/161 (22%), Positives = 56/161 (34%), Gaps = 19/161 (11%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP + + V + T+ W PP G L GY ++ + W + +T +
Sbjct: 745 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
Query: 207 SDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQP 266
+ L RV A N G SE Y ++ ++ E PK P
Sbjct: 805 TGLPTDAKIFVRVKAVNAAGASEPK---------------YYSQPILVKEIIEPPKIRIP 849
Query: 267 LADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGN 304
T G L + PRP++ W K+ +I N
Sbjct: 850 RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
Score = 34.7 bits (78), Expect = 0.13
Identities = 57/260 (21%), Positives = 93/260 (35%), Gaps = 38/260 (14%)
Query: 98 RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDI--LVIERPGPPQSIKLV 155
R +R + IL I A +AD+ Y + G A ++D+ L I P Q++ L
Sbjct: 413 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
Query: 156 DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSY 215
+ P G G VQ++D L+ H+ + L+I N+
Sbjct: 473 KEICLKCEISENIP---GKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANA- 518
Query: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC----T 271
+T D A Y A+ + PK D T
Sbjct: 519 -----------------LTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
Query: 272 TVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
+ G +L + P PK +W + +K ++G+ + R ++ +L I D G+
Sbjct: 562 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 621
Query: 331 YTCKAVNPLGEASVDCRVDV 350
Y N GEA +V V
Sbjct: 622 YHINLKNEAGEAHASIKVKV 641
>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
Length = 1274
Score = 344 bits (882), Expect = 8e-95
Identities = 162/324 (50%), Positives = 214/324 (66%)
Query: 30 ASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH 89
A PG + P + I + P++ LPR LRQT +KVG+ VNLLIPFQGKP+PQ WT
Sbjct: 950 AGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTK 1009
Query: 90 DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
+G L VS+RN D+ILFIR A+R SG YQ+ V++ +E AT+ + V+++P PP
Sbjct: 1010 EGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTYQVTVRIENMEDKATLVLQVVDKPSPP 1069
Query: 150 QSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDL 209
Q +++ D WG + LEW PPQD GNT L GYTVQKAD K+ WFTVLEHY RT C+V +L
Sbjct: 1070 QDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQKADKKTMEWFTVLEHYRRTHCVVPEL 1129
Query: 210 IIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLAD 269
IIGN Y FRVF++N G S+ A T + I + Y+ + DFSEAP FTQPL +
Sbjct: 1130 IIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRPGITYEPPNYKALDFSEAPSFTQPLVN 1189
Query: 270 CTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGG 329
+ + GY L C VR SP+PKI W KN +D+ + ++R + G+ +LEIRKP PFDGG
Sbjct: 1190 RSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGEDARFRMFSKQGVLTLEIRKPCPFDGG 1249
Query: 330 IYTCKAVNPLGEASVDCRVDVKVP 353
IY C+A N GEA +CR++V+VP
Sbjct: 1250 IYVCRATNLQGEARCECRLEVRVP 1273
Score = 73.2 bits (178), Expect = 3e-13
Identities = 66/260 (25%), Positives = 103/260 (39%), Gaps = 41/260 (15%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQL--------LPPIEEHPKIWL--PRALRQTY 63
KL + + +PAD P A + + +L P +E PKI L P + T
Sbjct: 600 KLTIDDVTPADEADYSFVPEGFACNLSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPDTI 659
Query: 64 IRKVGDTVNLLIPFQGKPKPQAIWTH-----------------------DGCALDTR--- 97
+ G+ + L +P G P P IW D D +
Sbjct: 660 VVVAGNKLRLDVPISGDPAPTVIWQKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLC 719
Query: 98 ----RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIK 153
RV V + SI + A++ D G Y + V+ E + + VI+ P P + K
Sbjct: 720 ETEGRVRVETTKDRSIFTVEGAEKEDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPK 779
Query: 154 LVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIG 212
+ +V S T++W PP G +LGY +++ KS W + + S +I G
Sbjct: 780 ISNVGEDSCTVQWEPPAYDGGQPILGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEG 839
Query: 213 NSYAFRVFAENQCGLSETAP 232
Y RV+A N G+S +P
Sbjct: 840 VVYEMRVYAVNAIGMSRPSP 859
Score = 56.2 bits (134), Expect = 4e-08
Identities = 45/172 (26%), Positives = 68/172 (39%), Gaps = 19/172 (11%)
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
A+ + I P P + + DV + +L+W PP+ G L GY+V+ W
Sbjct: 860 ASQPFMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAA 919
Query: 196 LEHY-HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQ 254
L+ TS +V DL G FRV A N G AP+TT T+
Sbjct: 920 LQGLTEHTSILVKDLPTGARLLFRVRAHNMAG--PGAPVTT-------------TEPVTV 964
Query: 255 RDFSEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
++ + P+ P T+ G L + PRP++ W K + G
Sbjct: 965 QEILQRPRLQLPRHLRQTIQKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAG 1016
>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
Length = 1141
Score = 342 bits (876), Expect = 4e-94
Identities = 157/313 (50%), Positives = 216/313 (69%)
Query: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVS 100
P + I E PKI LPR LRQTYIRKVG+ +NL++PFQGKP+PQ +WT G LDT RV
Sbjct: 828 PVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVH 887
Query: 101 VRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGF 160
VR + D++ F+R+A R+DSG Y+L VQ+ ++ TATI I V+E+ GPP ++ + +VWG
Sbjct: 888 VRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGT 947
Query: 161 SATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVF 220
+A +EW P+D GN+ ++GY VQKAD K+ WF V E TSC VSDLI+GN Y FRV+
Sbjct: 948 NALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVY 1007
Query: 221 AENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQL 280
EN CGLS++ ++ + A I K +K + + DF APKF PL D V GY+ L
Sbjct: 1008 TENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAAL 1067
Query: 281 FCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
C VR P+PK++W+KNKM+I+ +PK+ + G+ +L IR+P PFD G YTC+AVN LG
Sbjct: 1068 NCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELG 1127
Query: 341 EASVDCRVDVKVP 353
EA +C+++V+VP
Sbjct: 1128 EALAECKLEVRVP 1140
Score = 79.7 bits (195), Expect = 4e-15
Identities = 56/190 (29%), Positives = 85/190 (44%), Gaps = 6/190 (3%)
Query: 46 PIEEHPKIWLP---RALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR--RVS 100
P +E PKI L + + G+ + L + G+P P A W T R
Sbjct: 534 PKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEVFTTTEGRTR 593
Query: 101 VRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGF 160
+ S I AQR D GRY ++V E A+I + V++ P PP+++++ V
Sbjct: 594 IEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEAVRITSVGED 653
Query: 161 SATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRV 219
A L W PP G + GY V++ S W + E + T+ + +I G Y RV
Sbjct: 654 WAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMIEGILYEMRV 713
Query: 220 FAENQCGLSE 229
FA N G+S+
Sbjct: 714 FAVNAIGVSQ 723
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/152 (26%), Positives = 57/152 (37%), Gaps = 19/152 (12%)
Query: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVS 207
P + + DV + TL+W PP G + GY V+ S W E R V
Sbjct: 740 PLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVK 799
Query: 208 DLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPL 267
+L G FRV N G SE A + + T+ R+ +E PK P
Sbjct: 800 NLPTGARILFRVVGVNIAGRSEPATLA-------QPVTI--------REIAEPPKIRLPR 844
Query: 268 ADCTTV---TGYNTQLFCCVRASPRPKIIWLK 296
T G L + PRP+++W K
Sbjct: 845 HLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTK 876
Score = 31.2 bits (69), Expect = 1.5
Identities = 68/304 (22%), Positives = 109/304 (35%), Gaps = 38/304 (12%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-----RVSVRNGEQDSILFIREAQRADSG 121
VGD V + + + Q +W DG L R + + IL + + D G
Sbjct: 359 VGDRVEMAVEVS-EEGAQVMWMKDGVELTREDSFKARYRFKKDGKRHILIFSDVVQEDRG 417
Query: 122 RYQLRVQLGGLEATATIDILVIE--RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLG 179
RYQ+ G EA ++ +E + ++K + F E + + TG G
Sbjct: 418 RYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKC--EVSDEKVTGKWYKNG 475
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAH 239
V+ + + H R +V D + F + LS +A + +
Sbjct: 476 VEVRPSKR------ITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKL-----N 524
Query: 240 IQKAATVYKTKGFAQRDFSEAPKFTQPLADCTT------VTGYNTQLFCCVRASPRPKII 293
+ Y K E PK + T+ V G +L + P P
Sbjct: 525 FLEIKVEYVPK-------QEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVAT 577
Query: 294 WLK-NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE--ASVDCRVDV 350
WLK +++ + R + S I D G YT K NP+GE AS+ +V V
Sbjct: 578 WLKGDEVFTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQV-V 636
Query: 351 KVPN 354
VP+
Sbjct: 637 DVPD 640
>gi|148839296 immunoglobulin-like and fibronectin type III domain
containing 1 [Homo sapiens]
Length = 868
Score = 134 bits (338), Expect = 9e-32
Identities = 90/299 (30%), Positives = 131/299 (43%), Gaps = 3/299 (1%)
Query: 46 PIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGE 105
P+ PK + + + KVGDTV + + F+ P P+ W DG L R V+V
Sbjct: 558 PVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPLPKRSVTVTKDG 617
Query: 106 QDSILFIREAQRADSGRYQLRVQ-LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATL 164
+L I A +DSG Y + ++ L G E + I V P P I L + + T
Sbjct: 618 LTQLL-IPVAGLSDSGLYTVVLRTLQGKEVAHSFRIRVAACPQAPGPIHLQENVPGTVTA 676
Query: 165 EWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQ 224
EW P D L Y V + G W + H + ++ G+ Y FRV A+N+
Sbjct: 677 EWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAADRIHTNRFTLLGILPGHEYHFRVVAKNE 736
Query: 225 CGLSETAPITTDLA-HIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCC 283
G S+ + + Q+ K + + D S+ P+F L G + C
Sbjct: 737 LGASKPSDTSQPWCIPRQRDRFTVKAPCYREPDLSQKPRFLVGLRSHLLPQGCECCMSCA 796
Query: 284 VRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
V+ SPRP + W KN ++GNP + LG+CSL I P D G Y A N LG+A
Sbjct: 797 VQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTLGQA 855
Score = 72.8 bits (177), Expect = 4e-13
Identities = 56/201 (27%), Positives = 86/201 (42%), Gaps = 7/201 (3%)
Query: 36 AGSPTPQLLPPIEEHPKIW--LPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCA 93
AG + +++ P I + LR+ + K G V + IPFQ QA W DG
Sbjct: 146 AGDQQSEATLTVQDSPTIAPDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAE 205
Query: 94 L---DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
+ R V G+ + L + A R D G+Y + ++ G A + + VI++P PPQ
Sbjct: 206 VVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQ 265
Query: 151 S-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTSCIVSD 208
+++ D L W PP+D G + Y V++ W V E T+ +
Sbjct: 266 GPMEVQDCHRAGVCLRWRPPRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAH 325
Query: 209 LIIGNSYAFRVFAENQCGLSE 229
+ G Y FRV A G E
Sbjct: 326 VEPGRKYTFRVRAVTSEGAGE 346
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/141 (27%), Positives = 57/141 (40%), Gaps = 8/141 (5%)
Query: 99 VSVRNGEQDSILFIREAQRADSGRYQLRVQL----GGLEATATIDILVIER--PGPPQSI 152
+ V DS F +A +Y RV+ G EA + +ILV P P +
Sbjct: 309 LKVGEAPADSTTFT-DAHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEALPKAPSAP 367
Query: 153 KLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRTSCIVSDLII 211
++ TL WT P+ G+ +LGY +++ S W V + V+D+
Sbjct: 368 AILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRWTVADVRQ 427
Query: 212 GNSYAFRVFAENQCGLSETAP 232
G Y FRV A G E P
Sbjct: 428 GCQYEFRVTAVAPSGPGEPGP 448
Score = 43.5 bits (101), Expect = 3e-04
Identities = 50/192 (26%), Positives = 76/192 (39%), Gaps = 23/192 (11%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
PG +++++ D S TL W P GY V+ + S W + T+
Sbjct: 462 PGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLPCHVGTVPVTTY 521
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF- 263
L G Y RV A N+ G S+ + + T + +A V + PKF
Sbjct: 522 TAKGLRPGEGYFVRVTAVNEGGQSQPSALDT----LVQAMPV-----------TVCPKFL 566
Query: 264 -TQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR-ALTHLGICSLEI 320
D TV G ++ A P P++ WLK+ + + PK +T G+ L I
Sbjct: 567 VDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWLKDGLPL---PKRSVTVTKDGLTQLLI 623
Query: 321 RKPGPFDGGIYT 332
G D G+YT
Sbjct: 624 PVAGLSDSGLYT 635
>gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]
Length = 1326
Score = 127 bits (320), Expect = 1e-29
Identities = 92/327 (28%), Positives = 140/327 (42%), Gaps = 17/327 (5%)
Query: 35 GAGSPTP-----QLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH 89
G G P + +PP PK L L+ + + G + + F G P P IW
Sbjct: 982 GVGEPVELDKGVRAMPP-PAAPKFDLSARLKSHMVVRAGTALCIHAAFSGSPPPDVIWQK 1040
Query: 90 DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
DG R ++ + S I +R+DSG Y++ +Q EA I + V + P PP
Sbjct: 1041 DGVPTKGRE-TITKSKNHSQFLINSTKRSDSGVYRILLQNEFGEARYDIHVRVADFPRPP 1099
Query: 150 QSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDL 209
+++L + + TL W D Y + K D + W+T E V+ L
Sbjct: 1100 TNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKRDASTATWYTAAERVFSNKYTVTGL 1159
Query: 210 IIGNSYAFRVFAENQCGLSE------TAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
+ G Y FRV A N+ G SE T I D IQ + K K + ++D+ AP+F
Sbjct: 1160 LPGRKYYFRVVARNEIGDSEPLDSRDTWLINKD--QIQDLSA--KLKPYEKKDWRHAPRF 1215
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
PL T + G + + C +PRP + K ++I N K+ + G+C+L I
Sbjct: 1216 VTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANSKFWYNSTSGVCTLVIPTC 1275
Query: 324 GPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y+ N LG+ C + V
Sbjct: 1276 TLKDSGDYSVLVENELGKDRSSCTLTV 1302
Score = 95.5 bits (236), Expect = 6e-20
Identities = 60/212 (28%), Positives = 105/212 (49%), Gaps = 13/212 (6%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
KVG T ++ +PF+GKP P+ W DG + + RVS+ GE ++L I R DSG
Sbjct: 620 KVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQALLTISNCVREDSGLIL 679
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
L+++ ATAT+ + V++RP PPQ ++ +++ G ++W P+D G + + V+
Sbjct: 680 LKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVE 739
Query: 184 KADTKSGLWFTVLEHYHR-TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQK 242
+ W + E + T+ + + G +Y FR+ A N G+S+ P+ T+
Sbjct: 740 RRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSD--PLETE------ 791
Query: 243 AATVYKTKGFAQRDFSEAPKFTQPLADCTTVT 274
V+ F+ P+ T + T+T
Sbjct: 792 --EVFAGNPIEPPGFASQPQVTDVTKEAVTIT 821
Score = 52.8 bits (125), Expect = 5e-07
Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 9/135 (6%)
Query: 101 VRNGEQDSILFIREAQRADSGR-YQLRVQLGGLEATA----TIDILV---IERPGPPQSI 152
++ GE D + + + G+ YQ R+ E + T ++ IE PG
Sbjct: 749 IKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPIEPPGFASQP 808
Query: 153 KLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLII 211
++ DV + T+ W P G +LGY V++ S LW V + T C V L+
Sbjct: 809 QVTDVTKEAVTITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLE 868
Query: 212 GNSYAFRVFAENQCG 226
Y FRV A N+ G
Sbjct: 869 DTEYEFRVIAVNKAG 883
Score = 35.0 bits (79), Expect = 0.10
Identities = 58/271 (21%), Positives = 103/271 (38%), Gaps = 33/271 (12%)
Query: 80 KPKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATA 136
K +P +W +G L D ++V L I++A+ +DSG + +A
Sbjct: 353 KKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNLVQKAQL 412
Query: 137 TIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
TID + I+ +++++ + A LE + T L + G +++
Sbjct: 413 TIDRIPIKFVSNLKNVRVKE--RSRACLEC---ELTSKDVTLRWKKDGQLLMHGTKYSMN 467
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE---TAPITTDLAHIQKAATVYKTKGFA 253
R I+ D + + + V A +E TA +T + ++ ATV
Sbjct: 468 HEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVE----ERLATV------- 516
Query: 254 QRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL 313
++D TG +L C V + + +WLK+ +I P + +
Sbjct: 517 ----------KSGMSDVHAATGSPAEL-CVVLNDEKVEGVWLKDGKEITDLPGMQIVKQG 565
Query: 314 GICSLEIRKPGPFDGGIYTCKAVNPLGEASV 344
+ L GP G YT +A EASV
Sbjct: 566 AVHKLIFPSMGPEHEGKYTFRAKGTESEASV 596
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 113 bits (283), Expect = 2e-25
Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 5/177 (2%)
Query: 62 TYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADS 120
+Y +VG + + +P G+PKP WT DG L T R++V + + L I+E + D
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 23297
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLG 179
G+Y + V + TA+I+I+ +++P PP+ +K DV S TL W PP TG +
Sbjct: 23298 GQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITN 23357
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETAPI 233
Y VQK DT + +W V RT+ V+ L G Y FR+FAEN+ G S E+ PI
Sbjct: 23358 YIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI 23414
Score = 112 bits (280), Expect = 5e-25
Identities = 67/189 (35%), Positives = 100/189 (52%), Gaps = 4/189 (2%)
Query: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRV 99
P + IE P + LP T+ K + + + +PF+G+P+ W DG L +T RV
Sbjct: 25385 PVIARDIEIKPSVELPF---HTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRV 25441
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWG 159
+V + + + L I+EA + D G Y+L V T I I+V++RPGPP I++ +V
Sbjct: 25442 NVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSC 25501
Query: 160 FSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRV 219
S T+ W PP+ G + Y V+K +T S W V + RTS + L G+ Y FRV
Sbjct: 25502 DSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRV 25561
Query: 220 FAENQCGLS 228
AEN+ G S
Sbjct: 25562 CAENRYGKS 25570
Score = 110 bits (275), Expect = 2e-24
Identities = 67/212 (31%), Positives = 105/212 (49%), Gaps = 8/212 (3%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLI 75
+VK + A P + S PQ+ EE P + +R+T I K G + + +
Sbjct: 26156 RVKSVNKVGASDP-------SDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTV 26208
Query: 76 PFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEAT 135
PF+G+P P +W+ L TR V + + L I A R DSG+Y L +Q A+
Sbjct: 26209 PFRGRPVPNVLWSKPDTDLRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAAS 26267
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
T+ + V++ PGPP +I + DV SA L W P++ G + Y ++K + W +V
Sbjct: 26268 LTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSV 26327
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
+ +R S V++L G Y FRV EN+ G+
Sbjct: 26328 TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 26359
Score = 108 bits (270), Expect = 7e-24
Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 6/185 (3%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD-GCALDTRRVSVRNGEQDSI 109
P+I L LR+ + T+ L +P +G+P P+ W D G +LD + S+ + ++
Sbjct: 21858 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIESTSSYTL 21915
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPP 169
L + R DSG+Y L V+ +A +++ V++ PGPPQ +K+ +V S TL W PP
Sbjct: 21916 LIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPP 21975
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL-- 227
G + + Y V+K ++ + TV + H+TS V L G SY FRV AEN+ G+
Sbjct: 21976 LLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGL 22035
Query: 228 -SETA 231
+ETA
Sbjct: 22036 PAETA 22040
Score = 108 bits (270), Expect = 7e-24
Identities = 68/206 (33%), Positives = 102/206 (49%), Gaps = 6/206 (2%)
Query: 35 GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G G P P I E P+I L ALR + I K G+ V +LIPF+G+P P W D
Sbjct: 27249 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKD 27308
Query: 91 GCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG-GLEATATIDILVIERPGP 148
L + R S+ N + S+L I + R D+G+Y L ++ G G ++T+ + V++ P
Sbjct: 27309 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAA 27368
Query: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
Q +++ V + TL W PP G + ++ Y ++K D W V TS + D
Sbjct: 27369 CQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLID 27428
Query: 209 LIIGNSYAFRVFAENQCGLSETAPIT 234
L + FRV AEN+ G+ E T
Sbjct: 27429 LSEKTPFFFRVLAENEIGIGEPCETT 27454
Score = 107 bits (266), Expect = 2e-23
Identities = 75/252 (29%), Positives = 122/252 (48%), Gaps = 14/252 (5%)
Query: 57 RALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREA 115
+ L T+ G+ + + +PF G+P P W D L T RV+ + E +S+L I++A
Sbjct: 22151 KLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDA 22210
Query: 116 QRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGN 174
R D G Y +++ EA T++++V+++PGPP +K+ +V S TL W PP+ G
Sbjct: 22211 CREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGG 22270
Query: 175 TALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETA 231
+++ Y V+K DT + W V RT+ L G Y FR+ AEN+ G S +
Sbjct: 22271 SSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE 22330
Query: 232 PITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLAD-CTTVTGYNTQLFCCVRASPRP 290
P + RD E ++ +P++D + V GY+ + R
Sbjct: 22331 PTVAQYPFKVPGPPGTPVVTLSSRDSMEV-QWNEPISDGGSRVIGYH------LERKERN 22383
Query: 291 KIIWLK-NKMDI 301
I+W+K NK I
Sbjct: 22384 SILWVKLNKTPI 22395
Score = 106 bits (265), Expect = 3e-23
Identities = 62/192 (32%), Positives = 102/192 (53%), Gaps = 6/192 (3%)
Query: 39 PTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR- 97
P L+PP E L LR+T I + G T+ L +P +G+P P+ W+ L R
Sbjct: 19684 PKDILIPPEGE-----LDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRI 19738
Query: 98 RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDV 157
+ +++ + D+ L + D+G+Y L ++ + TI + V++ PGPP ++ + ++
Sbjct: 19739 GLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEI 19798
Query: 158 WGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAF 217
SA + W PP G + ++ Y VQK D + W TV +TS V++L G SY F
Sbjct: 19799 SKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFF 19858
Query: 218 RVFAENQCGLSE 229
RVFAEN+ G+ +
Sbjct: 19859 RVFAENEYGIGD 19870
Score = 105 bits (263), Expect = 5e-23
Identities = 62/203 (30%), Positives = 100/203 (49%), Gaps = 7/203 (3%)
Query: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRV 99
P + + P + LP TY + G+ + + IP G+P+P W DG L T RV
Sbjct: 24302 PVIAKDLTIQPSLKLPF---NTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRV 24358
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVW 158
+V ++L I+E + D G+Y + AT + ++V+E+PGPP ++ +V
Sbjct: 24359 NVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVS 24418
Query: 159 GFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFR 218
+ W PP TG + Y V+K DT + W V RT+ ++ L G Y FR
Sbjct: 24419 ADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFR 24478
Query: 219 VFAENQCGLSETAPITTDLAHIQ 241
+FAEN+ G ++AP+ + +Q
Sbjct: 24479 IFAENRYG--KSAPLDSKAVIVQ 24499
Score = 104 bits (259), Expect = 1e-22
Identities = 71/226 (31%), Positives = 104/226 (46%), Gaps = 13/226 (5%)
Query: 12 GSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTV 71
G K K + A+ +G QLLPP KI +P + K G +
Sbjct: 18866 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPP-----KILMPEQITI----KAGKKL 18916
Query: 72 NLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG 130
+ GKP P W + + + ++V + SIL I++ R DSG Y L +
Sbjct: 18917 RIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 18976
Query: 131 GLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKS 189
T I ++V++ PGPPQ + D+ + +L W P + G + + Y V+K D
Sbjct: 18977 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSR 19036
Query: 190 GLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITT 235
G W T L +TSC V LI G Y FRV AEN+ G+SE P+T+
Sbjct: 19037 GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE--PLTS 19080
Score = 103 bits (257), Expect = 2e-22
Identities = 60/191 (31%), Positives = 97/191 (50%), Gaps = 4/191 (2%)
Query: 48 EEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQ 106
+E P+I+L L K G + L GKP+P+ WT L +R+++ N +
Sbjct: 13685 QEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK 13744
Query: 107 DSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEW 166
S + I +++R+D+G Y + ATA +++ V+++PGPP + + DV S L W
Sbjct: 13745 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 13804
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
PP+D G + + Y V++ T S +W + T+ + LI Y FRV AEN G
Sbjct: 13805 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 13864
Query: 227 LSE---TAPIT 234
+ E +PIT
Sbjct: 13865 VGEPVQASPIT 13875
Score = 102 bits (255), Expect = 4e-22
Identities = 57/204 (27%), Positives = 101/204 (49%), Gaps = 6/204 (2%)
Query: 36 AGSPTPQLLPPIE-----EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
AG P ++P +E P L LR+T + + G ++ + +P +G+P P+ WT D
Sbjct: 20754 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 20813
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
L R ++ N E ++L I E R D+G++ + ++ + + +++ V++ PGP
Sbjct: 20814 NINLKNR-ANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 20872
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
+++ D+ S TL W P G + + Y V+K + + T H+ + V+ L
Sbjct: 20873 NLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLS 20932
Query: 211 IGNSYAFRVFAENQCGLSETAPIT 234
G Y FRV AEN+ G+ E T
Sbjct: 20933 EGCEYFFRVMAENEYGIGEPTETT 20956
Score = 102 bits (253), Expect = 7e-22
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 2/190 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDT-RRVSVRNGEQDSI 109
P + L L + + K G TV +G P P A WT DG + T +V S+
Sbjct: 17508 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 17567
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L I+ R D+G YQ+ V T + + V++ PGPP I ++DV T+ W P
Sbjct: 17568 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP 17627
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P+D G + ++ Y V+K DT+ W V +T + L G Y FRV AEN+ G+
Sbjct: 17628 PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVG 17687
Query: 229 ETAPITTDLA 238
T +A
Sbjct: 17688 PPLDSTPTVA 17697
Score = 101 bits (252), Expect = 9e-22
Identities = 61/176 (34%), Positives = 93/176 (52%), Gaps = 10/176 (5%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCALD---TRRVSVRNGEQDSILFIREAQRADSGR 122
K GDT+ L +GKP P+ WT D A D + RV + S + +A+R+D G+
Sbjct: 18214 KAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGK 18273
Query: 123 YQLRVQ--LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY 180
Y + G A AT+++L ++PGP +++K+VDV T+ W PP+D G + Y
Sbjct: 18274 YVVTATNTAGSFVAYATVNVL--DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNY 18331
Query: 181 TVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL---SETAPI 233
++K +TK +W T V+ LI GN Y FRV AEN+ G +E+ P+
Sbjct: 18332 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPV 18387
Score = 101 bits (252), Expect = 9e-22
Identities = 61/199 (30%), Positives = 96/199 (48%), Gaps = 2/199 (1%)
Query: 32 PGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDG 91
PG+ A P + + E+P L ++ + G + L IP +GKP P WT +G
Sbjct: 30115 PGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG 30174
Query: 92 CALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS 151
+ ++R + E + L I+EA R DSG Y L ++ + I + VI P P+
Sbjct: 30175 QDI-SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEG 30233
Query: 152 -IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
++ D+ S + W PP D G +LGY +++ + W+T+ TS +V L
Sbjct: 30234 PLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLK 30293
Query: 211 IGNSYAFRVFAENQCGLSE 229
Y FRV AENQ G+S+
Sbjct: 30294 ENVEYHFRVSAENQFGISK 30312
Score = 101 bits (251), Expect = 1e-21
Identities = 86/307 (28%), Positives = 134/307 (43%), Gaps = 30/307 (9%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRR-VSVRNGEQDSI 109
P I LP + + G +V L GKP P W D L T V V N +
Sbjct: 26870 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 26929
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
+ I++A R +SG Y+L+++ A+ATI + ++++PGPP I+ V TL W P
Sbjct: 26930 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRP 26989
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P D G + Y V+K +T +W V EH + +I GN Y FRV A N+ G+
Sbjct: 26990 PADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIG 27049
Query: 229 ETAPITTDLAHIQKAATVYKTKGFAQ----RDFSEAPKFTQPLAD-CTTVTGY------- 276
E P+ +D + A G + S +++P+AD + ++GY
Sbjct: 27050 E--PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDK 27107
Query: 277 -NTQLFCCVRAS---PRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYT 332
+ F ++ + R K+ L D Q YR +C++ GPF
Sbjct: 27108 KSLGWFKVLKETIRDTRQKVTGLTENSDYQ----YR------VCAVNAAGQGPFSEPSEF 27157
Query: 333 CKAVNPL 339
KA +P+
Sbjct: 27158 YKAADPI 27164
Score = 100 bits (248), Expect = 3e-21
Identities = 58/170 (34%), Positives = 89/170 (52%), Gaps = 4/170 (2%)
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWT--HDGCALDTRRVSVRNGEQDSILFIREAQRADS 120
Y+ K L IP +GKP P W D A DTR VSV + ++ L + + Q++D+
Sbjct: 19992 YLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTR-VSVESSAVNTTLIVYDCQKSDA 20050
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLG 179
G+Y + ++ TI I V+ +PG P IK +V + TL+W PP+D G + +
Sbjct: 20051 GKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITN 20110
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
Y ++K D+ + W T +T+ V+ L G Y FRV AEN+ G+ E
Sbjct: 20111 YILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 20160
Score = 99.8 bits (247), Expect = 3e-21
Identities = 55/166 (33%), Positives = 83/166 (50%), Gaps = 1/166 (0%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQL 125
V + + +L+P G P+P A W L+T RV ++ + L I ++R+D G Y L
Sbjct: 13408 VPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTL 13467
Query: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
+++ + ID+ VI RP P+ +K D+ S L W PP D G + L GY V+K
Sbjct: 13468 KLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR 13527
Query: 186 DTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
+ W V++ V DL+ G Y F+V A N+CG E A
Sbjct: 13528 EVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573
Score = 99.8 bits (247), Expect = 3e-21
Identities = 62/201 (30%), Positives = 99/201 (49%), Gaps = 6/201 (2%)
Query: 35 GAGSPTPQLLPPIE----EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G P LLP + E P+I + T + G + + IP GKP P+ + D
Sbjct: 26454 GLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRD 26513
Query: 91 GCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
G L T R + ++ + ++E+ AD+GRY++ A I+I+V++RPGPP
Sbjct: 26514 GVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPP 26573
Query: 150 QS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
+ + D+ S TL+W PP+ G + + Y + K +T + +W V RT V
Sbjct: 26574 TGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMK 26633
Query: 209 LIIGNSYAFRVFAENQCGLSE 229
L G Y FR+ AEN+ G+S+
Sbjct: 26634 LTTGEEYQFRIKAENRFGISD 26654
Score = 99.4 bits (246), Expect = 4e-21
Identities = 61/234 (26%), Positives = 106/234 (45%), Gaps = 19/234 (8%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNL 73
+ +VK + A P + G+ + I+E P++++ + + K G + +
Sbjct: 15778 RFRVKAVNEAGESEPSDTTGEIPATD-------IQEEPEVFIDIGAQDCLVCKAGSQIRI 15830
Query: 74 LIPFQGKPKPQAIWTHDGCALDTRRVSVRN---------GEQDSILFIREAQRADSGRYQ 124
+G+P P++ W DG A + V + E S++ I E +R+ +G+Y
Sbjct: 15831 PAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYS 15890
Query: 125 LRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK 184
+ + + TA + V++ PGPP+ +K+ D+ S L W P D G + GY ++K
Sbjct: 15891 ITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEK 15950
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETAPITT 235
W V T+ +V DL+ Y FRV AEN+ G+ ET TT
Sbjct: 15951 RTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTT 16004
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/190 (32%), Positives = 92/190 (48%), Gaps = 5/190 (2%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSI- 109
P+I L A++ K G V L GKP P W DG L ++ Q ++
Sbjct: 19293 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE-GIKMAMQRNLC 19351
Query: 110 -LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTP 168
L + R DSG Y + + +ATI + V+++PGPP S+K+ ++ A L W P
Sbjct: 19352 TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEP 19411
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P + G + + Y V K +T W V TSC V LI G+ Y FR+ AEN+ G+
Sbjct: 19412 PLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVG 19471
Query: 229 ETAPITTDLA 238
+ P+ T+ A
Sbjct: 19472 D--PVFTEPA 19479
Score = 98.6 bits (244), Expect = 8e-21
Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQD 107
E PKI + + T I K G+ L G+P P W+ DG L+ T ++ ++ +
Sbjct: 21457 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS 21516
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEW 166
+ L +++ R DSG Y L G A ++ V++RPGPP+ + + +V L W
Sbjct: 21517 TNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSW 21576
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
PP D G + Y VQK +T W V T V+ L+ GN Y FRV A N+ G
Sbjct: 21577 FPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYG 21636
Query: 227 LSE 229
+ E
Sbjct: 21637 VGE 21639
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/225 (27%), Positives = 108/225 (48%), Gaps = 12/225 (5%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P+I + + T + G++ + GKP P W L +T R+ +++ + +
Sbjct: 22541 PRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS 22600
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L +++A R DSG Y L+ + E + T+++ V++RPGPP+ + + V TL W P
Sbjct: 22601 LSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKP 22660
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P G + ++ Y V++ +T +W V + SC V+ L+ GN Y FR+ A N+ G+
Sbjct: 22661 PLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 22720
Query: 229 ETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTV 273
E P+ ++ V F D +AP+ T D V
Sbjct: 22721 E--PLESE--------PVVAKNPFVVPDAPKAPEVTTVTKDSMIV 22755
Score = 98.2 bits (243), Expect = 1e-20
Identities = 60/200 (30%), Positives = 97/200 (48%), Gaps = 2/200 (1%)
Query: 29 QASPGQGAGSPTPQLLPPIE--EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAI 86
Q G G + + + P E E P+I L ++R+ I + G + L +G+P P+
Sbjct: 18580 QNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVT 18639
Query: 87 WTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERP 146
W G R+ V + + L I + R DSG+Y L + E +++ V++ P
Sbjct: 18640 WRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTP 18699
Query: 147 GPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIV 206
GP +K+ DV S + W PP++ G + + Y V+K + W TV +TS V
Sbjct: 18700 GPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHV 18759
Query: 207 SDLIIGNSYAFRVFAENQCG 226
++L+ GN Y FRV A N+ G
Sbjct: 18760 TNLVPGNEYYFRVTAVNEYG 18779
Score = 97.8 bits (242), Expect = 1e-20
Identities = 60/205 (29%), Positives = 102/205 (49%), Gaps = 5/205 (2%)
Query: 33 GQGAGSPTPQLLPPIE--EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G G + P + P + E P++ L LR+ + + G + + IPF+G+P P+ W+ +
Sbjct: 24002 GLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSRE 24061
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
T +V + G + L I R D+G+Y L+++ +A + + V++ PGPPQ
Sbjct: 24062 EGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQ 24120
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
++ + +V SA L W PP G + Y + K ++ + V +TS V +L
Sbjct: 24121 NLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLT 24180
Query: 211 IGNSYAFRVFAENQCGLSETAPITT 235
G Y FRV AEN+ G+ P+ T
Sbjct: 24181 EGAIYYFRVMAENEFGVG--VPVET 24203
Score = 97.8 bits (242), Expect = 1e-20
Identities = 56/179 (31%), Positives = 86/179 (48%), Gaps = 1/179 (0%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
P++ + +QT++ + G ++ L I +QG+P P A+W+ L R + + S L
Sbjct: 28355 PELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR-ADIHTTDSFSTL 28413
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQ 170
+ R D+G+Y L V+ + T + V++ PGPP I DV SATL W P
Sbjct: 28414 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPL 28473
Query: 171 DTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
G + Y V+K + W + E R V+DL G Y FRV A N+ G+ E
Sbjct: 28474 LDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGE 28532
Score = 97.4 bits (241), Expect = 2e-20
Identities = 60/179 (33%), Positives = 91/179 (50%), Gaps = 2/179 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P I L ++T G V L+IP G+P P A W G L ++ RV+V + +
Sbjct: 29736 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 29795
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L IRE D+G Y L ++ + TI ++++++PGPP IK+ ++ S T+ W P
Sbjct: 29796 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 29855
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
P+ G L GY V++ D W V E R++ + L GN Y FRV A N+ G+
Sbjct: 29856 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGI 29914
Score = 96.7 bits (239), Expect = 3e-20
Identities = 55/190 (28%), Positives = 94/190 (49%), Gaps = 5/190 (2%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQD 107
E P+I + R T + G+T L GKP P W ++ + R ++N +
Sbjct: 23621 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 23680
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEW 166
++L +++A R D G+Y LR + +++ V++RPGPP+ +++ V +L W
Sbjct: 23681 ALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW 23740
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
+PP G + + Y V+K +T W V S V+ L+ GN Y FR+ A N+ G
Sbjct: 23741 SPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYG 23800
Query: 227 LS---ETAPI 233
+ E+AP+
Sbjct: 23801 VGEPLESAPV 23810
Score = 94.7 bits (234), Expect = 1e-19
Identities = 62/198 (31%), Positives = 92/198 (46%), Gaps = 3/198 (1%)
Query: 30 ASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH 89
A A P P L+ E P++ L + + KVGDT+ L +G P P+ W
Sbjct: 17195 AGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKK 17254
Query: 90 DGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGP 148
+ T+ R+ V S L IR A D G Y L V+ T ++ +LV+++PGP
Sbjct: 17255 EDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGP 17312
Query: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
P+ +++ ++ S L W P D G + + Y V++ D S W + + S
Sbjct: 17313 PRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH 17372
Query: 209 LIIGNSYAFRVFAENQCG 226
L GN Y FRV AENQ G
Sbjct: 17373 LNEGNQYLFRVAAENQYG 17390
Score = 93.6 bits (231), Expect = 2e-19
Identities = 55/190 (28%), Positives = 91/190 (47%), Gaps = 6/190 (3%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD--TRRVSVRNGEQDS 108
P L + + G+T L +GKP P +W+ DG L+ R+ +++ Q +
Sbjct: 24705 PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKT 24764
Query: 109 ILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWT 167
L +++ R D G+Y L++ G + I + V++RPGPP+ +K+ V L W
Sbjct: 24765 TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 24824
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
PP G + Y ++K +T W V + V+ L+ GN Y FRV A N+ G+
Sbjct: 24825 PPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 24884
Query: 228 S---ETAPIT 234
E+ P+T
Sbjct: 24885 GEPLESGPVT 24894
Score = 93.6 bits (231), Expect = 2e-19
Identities = 55/187 (29%), Positives = 94/187 (50%), Gaps = 3/187 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQD 107
E P+I L LR+ + + T+ L + +G+P+P+ W +G D ++ V +
Sbjct: 25103 EPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSF-- 25160
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWT 167
++L I R DSGRY L ++ TA +++ V++ P P ++ + +V S TL W
Sbjct: 25161 TMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWE 25220
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
PP G + Y V+K +T + T+ + +T+ + +L G SY FRV A N+ G+
Sbjct: 25221 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280
Query: 228 SETAPIT 234
A T
Sbjct: 25281 GLPAETT 25287
Score = 93.6 bits (231), Expect = 2e-19
Identities = 64/205 (31%), Positives = 100/205 (48%), Gaps = 7/205 (3%)
Query: 45 PPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRN 103
P IE P L Q K G + +P G+P P+ W + L +T RVS+
Sbjct: 28641 PQIE--PTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT 28698
Query: 104 GEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSA 162
+ + L ++++ R DSGRY L ++ T ++ ++VI RPGP I++ V S
Sbjct: 28699 TKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESC 28758
Query: 163 TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAE 222
L W P+D G T + Y V+K ++ + W V RT V+ L Y+FRV +E
Sbjct: 28759 VLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSE 28818
Query: 223 NQCGLS---ETAPITTDLAHIQKAA 244
N+ G+S E+API + + +A
Sbjct: 28819 NRFGVSKPLESAPIIAEHPFVPPSA 28843
Score = 93.2 bits (230), Expect = 3e-19
Identities = 66/236 (27%), Positives = 103/236 (43%), Gaps = 11/236 (4%)
Query: 5 TAPEVAAGS--KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQT 62
T E+ G+ KL+V + A PP G P + +E P + L +++
Sbjct: 15062 TVKEIREGADYKLRVSAVNAAGEGPP--------GETQPVTVAEPQEPPAVELDVSVKGG 15113
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
G T+ + G+P P +WT + LD RV + N S L I++A R D GR
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGR 15173
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Y + A + V + PGP +K V L W+ P+D G + + G+ +
Sbjct: 15174 YVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 15233
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
++ D K W +E R+ C ++ L+ G Y FRV A+N+ G I LA
Sbjct: 15234 ERKDAKMHTWRQPIE-TERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILA 15288
Score = 93.2 bits (230), Expect = 3e-19
Identities = 57/200 (28%), Positives = 98/200 (49%), Gaps = 3/200 (1%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWT 88
+A G+ A P P ++ E P I L LR+ + G ++ L +P +G+P P+ W
Sbjct: 22918 KAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWG 22977
Query: 89 H-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPG 147
DG D + V + +L R DSG+Y L ++ +A + + V++ P
Sbjct: 22978 KVDGEIRDAAIIDVTSSFTSLVL--DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPS 23035
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVS 207
PP ++K+ ++ S ++ W PP G + + Y V+K + + V+ + H+ S +
Sbjct: 23036 PPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKID 23095
Query: 208 DLIIGNSYAFRVFAENQCGL 227
L G SY FRV AEN+ G+
Sbjct: 23096 QLQEGCSYYFRVTAENEYGI 23115
Score = 91.7 bits (226), Expect = 9e-19
Identities = 57/183 (31%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNL-LIPFQGKPKPQAIWTHDGCALDTRRVS-VRNGEQ 106
E P I L ++ K GDT+ L I GKP P++ W+ G + ++ + +
Sbjct: 20374 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 20433
Query: 107 DSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEW 166
S+L I+ A R D+G Y + + + V++ PGPP +++ +V ATL W
Sbjct: 20434 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTW 20493
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
TPP + G + + Y ++K +T LW V E + + LI GN Y FRV A N G
Sbjct: 20494 TPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 20553
Query: 227 LSE 229
E
Sbjct: 20554 KGE 20556
Score = 90.5 bits (223), Expect = 2e-18
Identities = 69/223 (30%), Positives = 96/223 (43%), Gaps = 7/223 (3%)
Query: 12 GSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRA-LRQTY----IRK 66
G + V+ + + Q AG P+ P+ + LP LR Y I K
Sbjct: 21019 GLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAK 21078
Query: 67 VGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
GD + + IP G+PKP W D T+RV+ +IL I E R+DSG Y L
Sbjct: 21079 AGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 21138
Query: 126 RVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK 184
+ E I I V + PGPP IK +V T W PP++ G + Y V+
Sbjct: 21139 TARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEM 21198
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
T S W + RT+ + L G Y FRV A+N+ G+
Sbjct: 21199 RQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGV 21241
Score = 90.1 bits (222), Expect = 3e-18
Identities = 56/191 (29%), Positives = 92/191 (48%), Gaps = 2/191 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P++ L R +VG T+ +L +G+P+P WT +G L +RV +
Sbjct: 17906 PEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE 17965
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPP 169
L I+EA RAD G+Y + + A + + V++RPGP Q++K+ +V + T+ W P
Sbjct: 17966 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENP 18025
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
D G + + + V+ W V + I ++L+ N Y FRV AEN+ G+
Sbjct: 18026 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGVGP 18084
Query: 230 TAPITTDLAHI 240
T T + I
Sbjct: 18085 TIETKTPILAI 18095
Score = 89.7 bits (221), Expect = 3e-18
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 4/173 (2%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGC-ALDTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+VG+ L + GKPKP+ W D L+ R ++ L +A+R+DSG+Y
Sbjct: 16831 RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYC 16890
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ V+ + V++RPGPP + +V + W PP D G + + Y ++
Sbjct: 16891 VVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIE 16950
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTD 236
K + +W V +T+C VS L+ G Y FR+ AEN G+S+ P+ +D
Sbjct: 16951 KKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISD--PLVSD 17001
Score = 89.7 bits (221), Expect = 3e-18
Identities = 61/227 (26%), Positives = 105/227 (46%), Gaps = 10/227 (4%)
Query: 5 TAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIE--EHPKIWLPRALRQT 62
T P++ G K + A+ G S + + P+E E P + L L++T
Sbjct: 29403 TVPDLKMGQKYSFRVAAVN-------VKGMSEYSESIAEIEPVERIEIPDLELADDLKKT 29455
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
+ G ++ L++ G+P P W+ G L +R + + E S+L + + R D+G+
Sbjct: 29456 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIVDKVNRYDAGK 29514
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Y + + + +AT+ + V + PGP S+K+ +V S T+ W P G + Y V
Sbjct: 29515 YTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIV 29574
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+K + + TV +T +S L+ G Y FRV EN G+ E
Sbjct: 29575 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 29621
Score = 89.4 bits (220), Expect = 5e-18
Identities = 51/201 (25%), Positives = 96/201 (47%), Gaps = 2/201 (0%)
Query: 31 SPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
S + + S P ++ E P++ + R + K G+ + + G+P P W D
Sbjct: 25767 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 25826
Query: 91 GCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
G ++ R R + + + ++L +++ R D+G+Y L ++ + ++ V+++PGPP
Sbjct: 25827 GIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPP 25886
Query: 150 QS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
+++ + +L W PQ+ G + Y V+K +T W TSC V+
Sbjct: 25887 AGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTK 25946
Query: 209 LIIGNSYAFRVFAENQCGLSE 229
L+ GN Y FRV N+ G+ E
Sbjct: 25947 LLKGNEYIFRVTGVNKYGVGE 25967
Score = 87.8 bits (216), Expect = 1e-17
Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 1/163 (0%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLR 126
G+ +++ +PF+ P P W DG + R++++N + L + ++ RAD+G Y +
Sbjct: 14401 GEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTIT 14460
Query: 127 VQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKAD 186
++ ATA+I++ VI PGP + IK D+ S L W PP+ G T +L Y +++ +
Sbjct: 14461 LENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERRE 14520
Query: 187 TKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ V+ ++ S V DLI Y FRV A N+ G E
Sbjct: 14521 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGE 14563
Score = 86.3 bits (212), Expect = 4e-17
Identities = 54/187 (28%), Positives = 92/187 (49%), Gaps = 8/187 (4%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
PKI + Q + VG + +++P+ PK +A W + L T+ + EQ S
Sbjct: 13000 PKI---KTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT-TAEQTSFR 13055
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQ 170
+ EA++ D GRY++ +Q +A I++ VI+ PGP +++++ + + +L W P
Sbjct: 13056 IL-EAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPL 13114
Query: 171 DTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGN-SYAFRVFAENQCGLSE 229
G + ++GY V++ D K W + V+ L G Y FRV A N+ G E
Sbjct: 13115 TDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE 13174
Query: 230 TAPITTD 236
P+ TD
Sbjct: 13175 --PVETD 13179
Score = 84.7 bits (208), Expect = 1e-16
Identities = 69/250 (27%), Positives = 111/250 (44%), Gaps = 13/250 (5%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
++G V+L +P++GKPKP W DG L ++ V E L I+ A++ G+Y
Sbjct: 27576 RIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 27635
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ + I ++ + P P+ I+ ++ S L W P+D G + Y+++
Sbjct: 27636 VILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 27695
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
K +T W V RT+ V +L+ Y FRV AEN+ G+S+ + +A Q
Sbjct: 27696 KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFR 27755
Query: 244 ATVYKTKGFAQRDFSEAPKFT--QPLAD-CTTVTGYNTQLFCCVRASPRPKIIWLK-NKM 299
K S+ T P+ D + VTG++ V R I+W K N
Sbjct: 27756 IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFH------VEKKERNSILWQKVNTS 27809
Query: 300 DIQGNPKYRA 309
I G +YRA
Sbjct: 27810 PISGR-EYRA 27818
Score = 82.8 bits (203), Expect = 4e-16
Identities = 56/206 (27%), Positives = 90/206 (43%), Gaps = 15/206 (7%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-TVLEHYHRT 202
++P P ++++ + S TL+W P+ G +LGY V+ + W + E
Sbjct: 30429 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 30488
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+ L+ Y FRVFAEN+ GLS ++ A KTK + EAP
Sbjct: 30489 QFTIGGLLEATEYEFRVFAENETGLSRP----------RRTAMSIKTKLTS----GEAPG 30534
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ + D TT G QL C + P P I W + ++ + KY+ + +L +
Sbjct: 30535 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 30594
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRV 348
D G+YTC A N +GE ++
Sbjct: 30595 EEQEDEGVYTCIATNEVGEVETSSKL 30620
Score = 80.5 bits (197), Expect = 2e-15
Identities = 52/183 (28%), Positives = 93/183 (50%), Gaps = 8/183 (4%)
Query: 59 LRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQR 117
L++ Y VG T+ L + + G+P P W H L ++ +++ N E + L ++ QR
Sbjct: 30634 LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQR 30693
Query: 118 -ADSGRYQLRVQLGGLEAT--ATIDILVIERPGPPQSIKLVD-VWGFSATLEWTPPQDTG 173
+G+Y +VQL + T A +D+ + ++P P +++ + SA + W PP D G
Sbjct: 30694 KTHAGKY--KVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 30751
Query: 174 NTALLGYTVQKADTKSGL-WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAP 232
+ + Y V+K + K G W V T+C + +L Y FRV A+N G+S+
Sbjct: 30752 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 30811
Query: 233 ITT 235
+++
Sbjct: 30812 VSS 30814
Score = 80.1 bits (196), Expect = 3e-15
Identities = 65/221 (29%), Positives = 96/221 (43%), Gaps = 7/221 (3%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKV--GDTV 71
+L + + DA Q GS + +E KI LP+ L G+ V
Sbjct: 30986 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 31045
Query: 72 NLLIPFQGKPKPQAIWTHDGCALDTR---RVSVRNGEQDSILFIREAQRADSGRYQLRVQ 128
++ IPF GKP P W +D +V V S++F +R D+G Y + +
Sbjct: 31046 SIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAGFYVVCAK 31104
Query: 129 LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTK 188
T+++ V + P PP+ +K+ DV S L WT P G + + Y V+K T
Sbjct: 31105 NRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT 31164
Query: 189 SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ W V T V +L SY FRV AEN+ GLS+
Sbjct: 31165 AERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLSK 31204
Score = 79.0 bits (193), Expect = 6e-15
Identities = 63/231 (27%), Positives = 98/231 (42%), Gaps = 34/231 (14%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIR-KVGDTVNLLIPFQGKPKPQAIW 87
+A G P+ + PP + I P+ + +T + K GD + L G P P W
Sbjct: 14655 RAENAAGISEPS-RATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITW 14713
Query: 88 THDGCALD-----------------------------TRRVSVRNGEQ-DSILFIREAQR 117
D + T+R+S+ N ++ +S L +R++ R
Sbjct: 14714 IKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLR 14773
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTAL 177
D G Y ++V+ A A + V++ PGPP + D+ S +W PP D G + +
Sbjct: 14774 PDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEI 14833
Query: 178 LGYTVQKAD-TK-SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
+ YT++K D TK W V V+ LI G Y FRV AEN+ G
Sbjct: 14834 INYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG 14884
Score = 77.0 bits (188), Expect = 2e-14
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
Query: 79 GKPKPQAIWTHDGCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATAT 137
GKP+P+ IWT LD +VS++ + + I+ R+DSG+Y L V+ +
Sbjct: 29073 GKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS 29132
Query: 138 IDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE 197
+ + V++ PGP + + V TL W+ PQ+ G + Y V++ +T W V
Sbjct: 29133 VMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEG 29192
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
S +V+ LI N Y FRV A N+ G
Sbjct: 29193 ECPTLSYVVTRLIKNNEYIFRVRAVNKYG 29221
Score = 75.5 bits (184), Expect = 7e-14
Identities = 53/193 (27%), Positives = 86/193 (44%), Gaps = 4/193 (2%)
Query: 64 IRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGR 122
I K G+++ + QG+P P+ W DG ++ R + + + + LF+R+A R G
Sbjct: 27969 IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGV 28028
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYT 181
Y + + A A I + V + PG I+ ++ G TL W P + G + Y
Sbjct: 28029 YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYI 28088
Query: 182 VQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQ 241
++K +T W + + S LI GN Y FRV A N+ G+ P+ +D Q
Sbjct: 28089 IEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGR--PLDSDPVVAQ 28146
Query: 242 KAATVYKTKGFAQ 254
TV G +
Sbjct: 28147 IQYTVPDAPGIPE 28159
Score = 74.7 bits (182), Expect = 1e-13
Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 2/178 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
P + L ++R + G + ++ GKP P W + L + ++ S +
Sbjct: 16522 PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP-QEATIETTAISSSM 16580
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLV-DVWGFSATLEWTPP 169
I+ QR+ G Y L + E TI + V++ PGP + L ++ S L W P
Sbjct: 16581 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 16640
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
+D G + + Y ++K ++ W V R + V LI G +Y FR+ AEN G+
Sbjct: 16641 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGM 16698
Score = 74.3 bits (181), Expect = 2e-13
Identities = 56/212 (26%), Positives = 86/212 (40%), Gaps = 16/212 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A + ERP PP I L+DV S +L W P+ G + +LGY V+ S
Sbjct: 22034 GLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSD 22093
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W T T ++ LI G Y+FRV A+N+ G+S+ ++ +
Sbjct: 22094 KWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPV------------- 22139
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
+D P F T + G + ++ P P + W K+ + ++ + A
Sbjct: 22140 --IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE 22197
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
+ L I+ D G Y K N GEA
Sbjct: 22198 STENNSLLTIKDACREDVGHYVVKLTNSAGEA 22229
Score = 74.3 bits (181), Expect = 2e-13
Identities = 55/216 (25%), Positives = 87/216 (40%), Gaps = 20/216 (9%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEH 198
+L I+ PP+++++ D+ S +L W P G + + GY V++ D G W +
Sbjct: 26762 VLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTN 26821
Query: 199 YHRTSCIVSDLIIGNSYAFRVFAENQCG-LSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
T I+S L + Y FRVFA N G +S + + + I D
Sbjct: 26822 VTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI---------------DS 26866
Query: 258 SEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
P PL V G + +L + P P I W K+ ++Q N
Sbjct: 26867 YGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD 26926
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ S+ I+ + G Y K N +G AS RV +
Sbjct: 26927 LASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 26962
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/226 (24%), Positives = 95/226 (42%), Gaps = 22/226 (9%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNL 73
+ +VK + A P A+ G P + P I+ L++ + G VN+
Sbjct: 16088 EFRVKAVNAAGVSKPSATVGP-CDCQRPDMPPSID----------LKEFMEVEEGTNVNI 16136
Query: 74 LIPFQGKPKPQAIW---------THDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+ +G P P W + DT V+ + L I +++R+D+G Y
Sbjct: 16137 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTH-VNKLVVDDTCTLVIPQSRRSDTGLYT 16195
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ A+ + + V+ RPGPP IK V TL W PP+D G + + Y ++
Sbjct: 16196 ITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIE 16255
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
K + W V + + L+ G+ Y FR+ A+N+ G+ E
Sbjct: 16256 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGE 16301
Score = 73.6 bits (179), Expect = 3e-13
Identities = 58/209 (27%), Positives = 91/209 (43%), Gaps = 20/209 (9%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH--YHRTS 203
PGPP + ++VD S +L WT P G T ++GY ++ + + W+ V + T
Sbjct: 29342 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 29401
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V DL +G Y+FRV A N G+SE + ++ +++ + ++ K
Sbjct: 29402 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIE-------IPDLELADDLKK 29454
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL--THLGICSLEIR 321
T T G + +L V P P I W K +D+ RA+ T L +
Sbjct: 29455 T-----VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS----RAIIDTTESYSLLIVD 29505
Query: 322 KPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
K +D G YT +A N G+ S V V
Sbjct: 29506 KVNRYDAGKYTIEAENQSGKKSATVLVKV 29534
Score = 72.8 bits (177), Expect = 4e-13
Identities = 58/208 (27%), Positives = 87/208 (41%), Gaps = 18/208 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP+++K D S L W PP++ G + + GY V++ S W E T
Sbjct: 13588 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 13647
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF-- 263
V+ L G YA+RV A N+ G S+ + T ++ + D EAP+
Sbjct: 13648 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAV---------------DTQEAPEIFL 13692
Query: 264 -TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ LA T G +L V P PKI W K M ++ + + ++ I
Sbjct: 13693 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVD 13752
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y +AVN G A+ V+V
Sbjct: 13753 SKRSDTGTYIIEAVNVCGRATAVVEVNV 13780
Score = 71.6 bits (174), Expect = 1e-12
Identities = 49/218 (22%), Positives = 86/218 (39%), Gaps = 16/218 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A I V E P PP I + DV S +L WT P+ G + ++ Y V+ S
Sbjct: 23116 GLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE 23175
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W + ++++L G Y FRV A N+ G S+ + +
Sbjct: 23176 KW-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPI------------- 23221
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
+D P + + G + ++ + P+P I W K+ + ++ +
Sbjct: 23222 --VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT 23279
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
L + +L I++ DGG Y N +G+ + +
Sbjct: 23280 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEI 23317
Score = 69.7 bits (169), Expect = 4e-12
Identities = 59/213 (27%), Positives = 82/213 (38%), Gaps = 16/213 (7%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRT 202
E+PG P + V S + W PP G + Y ++K + K W +V E T
Sbjct: 30823 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 30882
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
V +LI G Y FRV EN G SE + I+ + +AP
Sbjct: 30883 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPI-------------QAPH 30929
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHL-GICSLEI 320
F + L + N L C V P+P + W + K I KYR G L I
Sbjct: 30930 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLII 30989
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D +Y +A N G S ++V+VP
Sbjct: 30990 ASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 31022
Score = 69.3 bits (168), Expect = 5e-12
Identities = 59/215 (27%), Positives = 88/215 (40%), Gaps = 17/215 (7%)
Query: 137 TID-ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
T+D + E P PP + L DV SA+L W P+ G + +LGY V+ + W V
Sbjct: 24203 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 24262
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR 255
E + +V+ L G Y FRV A N+ G S+ P + I K T+
Sbjct: 24263 AES-KVCNAVVTGLSSGQEYQFRVKAYNEKGKSD--PRVLGVPVIAKDLTI--------- 24310
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
P P + G + ++ V PRP I W+K+ ++ +
Sbjct: 24311 ----QPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATS 24366
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I++ D G YT A N G A+ + V V
Sbjct: 24367 TVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 24401
Score = 68.9 bits (167), Expect = 6e-12
Identities = 60/212 (28%), Positives = 85/212 (40%), Gaps = 23/212 (10%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT---VLEHY 199
I +P PP + + +D S L W PP+ G + +LGY V+ W E
Sbjct: 17110 IAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESC 17169
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
T V+ L G +Y FRV A N G S D AH+ + V +D E
Sbjct: 17170 PETKYKVTGLRDGQTYKFRVLAVNAAGES-------DPAHVPEPVLV--------KDRLE 17214
Query: 260 APKF---TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC 316
P+ + G +L ++ P PK+ W K D + +T +G
Sbjct: 17215 PPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARI-DVTPVG-S 17272
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
LEIR DGGIY+ NP G +V +V
Sbjct: 17273 KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKV 17304
Score = 67.8 bits (164), Expect = 1e-11
Identities = 76/309 (24%), Positives = 123/309 (39%), Gaps = 41/309 (13%)
Query: 48 EEHPKIWLPRALRQTYIR-KVGDTVNLLIPFQGKPKPQAIWTHDGC-------ALDTRRV 99
E P I L ++R I+ K G+ V++ G P P+ W+ + AL +
Sbjct: 15392 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 15451
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWG 159
V E + L I +A R D G Y + + + V +RP PP+++ + D+
Sbjct: 15452 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKA 15511
Query: 160 FSATLEWTPPQDTGNTALLGYTVQKADT--KSGLWFTVLEHYHRTSCIVSDLIIGNSYAF 217
S L W P D G + + Y + K D K W V + LI Y F
Sbjct: 15512 ESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEF 15571
Query: 218 RVFAENQCGLSETAPITTDLAHIQKAATV----YKTKGFAQRDFSEAPKFTQPLAD-CTT 272
RV A N+ G+S+ +D IQ + K K A+ S +T PL + +
Sbjct: 15572 RVRAVNKYGISDEC--KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSP 15629
Query: 273 VTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKY-----RALTHLGICSLEIRKPGPFD 327
+TGY WL+ + +G+P + +T +G+ +E P +
Sbjct: 15630 ITGY-----------------WLEKRE--EGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 15670
Query: 328 GGIYTCKAV 336
G Y +A+
Sbjct: 15671 GVKYQFRAM 15679
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/216 (27%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF------ 193
+LV E P P +++VDV + TL W P G + L GY ++ + W
Sbjct: 29629 VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLK 29688
Query: 194 -TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGF 252
TVLEH V+ L G Y FR+ A+N+ G+SE T A TV +
Sbjct: 29689 PTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETVT-------AVTVQDLRVL 29735
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTH 312
D S T P G +L + P P W ++ + + TH
Sbjct: 29736 PTIDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH 29790
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
+ L IR+ D G YT + N G S +V
Sbjct: 29791 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 29826
Score = 67.0 bits (162), Expect = 2e-11
Identities = 57/213 (26%), Positives = 88/213 (41%), Gaps = 22/213 (10%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHR 201
IERP PP ++ D S L+W PP G + +LGY +++ + W ++
Sbjct: 13289 IERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPE 13348
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETA----PITTDLAHIQKAATVYKTKGFAQRDF 257
+ V+ L GN Y +RV AEN+ G+S+ + P+T D A ++ + A +D
Sbjct: 13349 LTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDL-----SAFKDG 13403
Query: 258 SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
E P+ TGY PRP W ++ + + T
Sbjct: 13404 LEV-IVPNPITILVPSTGY-----------PRPTATWCFGDKVLETGDRVKMKTLSAYAE 13451
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I D GIYT K N + S + V+V
Sbjct: 13452 LVISPSERSDKGIYTLKLENRVKTISGEIDVNV 13484
Score = 67.0 bits (162), Expect = 2e-11
Identities = 52/220 (23%), Positives = 82/220 (37%), Gaps = 16/220 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A T + V E P PP + LVDV +AT++W P+ G + + GY V+ S
Sbjct: 25281 GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSE 25340
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W T + +S L G Y FRV A N+ G S+ + +
Sbjct: 25341 KWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV------------- 25386
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
RD P P ++ + P+ + W K+ ++ +
Sbjct: 25387 --IARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVS 25444
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + SL I++ D G Y N G +V + V
Sbjct: 25445 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIV 25484
Score = 66.6 bits (161), Expect = 3e-11
Identities = 59/215 (27%), Positives = 88/215 (40%), Gaps = 21/215 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE--HYH 200
I+ PGPP I++ D S TL W+ P G +A+ GY V+ + W TV
Sbjct: 27164 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 27223
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
T +VS+L G +Y FRV A N G E + + +D EA
Sbjct: 27224 TTEYVVSNLKPGVNYYFRVSAVNCAGQGE---------------PIEMNEPVQAKDILEA 27268
Query: 261 PKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P+ +A T+V G + Q+ + P P + W K++ ++ + +Y
Sbjct: 27269 PEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL 27328
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
L I + D G Y N +GE V VKV
Sbjct: 27329 LTIPQVTRNDTGKYILTIENGVGEPK-SSTVSVKV 27362
Score = 65.9 bits (159), Expect = 5e-11
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 19/211 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHR 201
+ PGPP +K+ D + +LEW+ P G ++GY ++ G W V E +
Sbjct: 28251 VNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVK 28310
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
T V+DL G Y FRV A N G ++ +T + + + + D
Sbjct: 28311 TRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTA-------PELDIDANF 28363
Query: 262 KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL--GICSLE 319
K T + G + +LF + P P +W K N RA H +L
Sbjct: 28364 KQTHVVR-----AGASIRLFIAYQGRPTPTAVWSKP----DSNLSLRADIHTTDSFSTLT 28414
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ D G YT N G S+ V V
Sbjct: 28415 VENCNRNDAGKYTLTVENNSGSKSITFTVKV 28445
Score = 63.9 bits (154), Expect = 2e-10
Identities = 57/217 (26%), Positives = 87/217 (40%), Gaps = 21/217 (9%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY 199
++ ++ PP +++++ S TL WT P+ G L GY V+K D S W H
Sbjct: 20268 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKA-NHV 20326
Query: 200 HRTSC--IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
+ C V+DL+ G Y FR+ A+N G +A T+ +D
Sbjct: 20327 NVPECAFTVTDLVEGGKYEFRIRAKNTAGAI--------------SAPSESTETIICKDE 20372
Query: 258 SEAPKFT--QPLADCTTVTGYNTQLF--CCVRASPRPKIIWLKNKMDIQGNPKYRALTHL 313
EAP + D T+ +T + + P PK W K DI+ + + +
Sbjct: 20373 YEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTP 20432
Query: 314 GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I+ D G YT A NP G +V V
Sbjct: 20433 TSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 20469
Score = 63.5 bits (153), Expect = 3e-10
Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 26/215 (12%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW--FTVLEHYH 200
I +PGPP + K++D+ S L W+ P G + GY V+K D G W T +
Sbjct: 22835 IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGIN 22894
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
+T+ V L+ + Y FR+ A N+ G+ E A + + +K EA
Sbjct: 22895 KTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL---------------EA 22939
Query: 261 PKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL--GI 315
P L + G + +LF ++ P P++ W K + G + A+ +
Sbjct: 22940 PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGK----VDGEIRDAAIIDVTSSF 22995
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
SL + +D G YT N G S V V
Sbjct: 22996 TSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRV 23030
Score = 63.2 bits (152), Expect = 3e-10
Identities = 66/274 (24%), Positives = 113/274 (41%), Gaps = 40/274 (14%)
Query: 101 VRNGEQDSILFIREAQRADSGR------------YQLRVQL---GGLEATA-----TIDI 140
V E++SIL+ + SGR YQ RV GL + + T+ +
Sbjct: 27793 VEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAV 27852
Query: 141 LVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYH 200
++ PG P I DV + TL+W PP G + ++GY+++K
Sbjct: 27853 SPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVS 27909
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
V+ L G+ Y FR+ A N G ++ +++ + T RD +
Sbjct: 27910 ECQYTVTGLSPGDRYEFRIIARNAVG---------TISPPSQSSGIIMT-----RDENVP 27955
Query: 261 P--KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P +F D + +G + ++ V+ P P++ W K+ ++I+ LG S
Sbjct: 27956 PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTS 28015
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L +R G+YT +A N G A + +V V+
Sbjct: 28016 LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049
Score = 62.0 bits (149), Expect = 8e-10
Identities = 62/276 (22%), Positives = 113/276 (40%), Gaps = 26/276 (9%)
Query: 77 FQGKPKPQAIWTHDGCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEAT 135
F G P W +G + ++R ++ E+ +IL I + D+G+Y ++ + +
Sbjct: 7891 FTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDS 7950
Query: 136 ATIDILVIERPGPPQSIKLVDV-WGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT 194
+ IL++E P + ++ V V G SA+L+ T +G + K DTK T
Sbjct: 7951 CSAQILILEPPYFVKQLEPVKVSVGDSASLQC----QLAGTPEIGVSWYKGDTKLRPTTT 8006
Query: 195 VLEHYHR--TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGF 252
H+ + + + + I +S + AEN G + +A+ + T
Sbjct: 8007 YKMHFRNNVATLVFNQVDINDSGEYICKAENSVG--------------EVSASTFLT--- 8049
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTH 312
++ P F++ L D G C + S + W K+ ++ +P +
Sbjct: 8050 -VQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFL 8108
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
+L I K G Y+C A NP+G AS R+
Sbjct: 8109 DNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 8144
Score = 62.0 bits (149), Expect = 8e-10
Identities = 31/88 (35%), Positives = 48/88 (54%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP+ ++++++ +A L+WT P+ G + + Y V+K D + W TV T C
Sbjct: 14084 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 14143
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPI 233
V+ L G+ Y FRV AEN G S+ I
Sbjct: 14144 VTPLTEGSLYVFRVAAENAIGQSDYTEI 14171
Score = 61.2 bits (147), Expect = 1e-09
Identities = 56/213 (26%), Positives = 81/213 (38%), Gaps = 20/213 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRT 202
I+ PGPP + KL D +A L WT P G + +LGY V+ + W + +
Sbjct: 17801 IKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIR 17860
Query: 203 SCI--VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
C V LI GN Y FR+ A N G E + + +D
Sbjct: 17861 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL---------------AESVIAKDILHP 17905
Query: 261 PKFTQPLA--DCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P+ + D TV G ++ V+ P P I W K + + + L
Sbjct: 17906 PEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE 17965
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L+I++ D G Y A N G A V+V
Sbjct: 17966 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNV 17998
Score = 60.8 bits (146), Expect = 2e-09
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 9/142 (6%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
+EA + D+ PGPP ++ + DV F +L W PP+ G + Y ++ D S
Sbjct: 13182 VEARSKYDV-----PGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIR 13236
Query: 192 WFTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGL---SETAPITTDLAHIQKAATVY 247
W T + S V+D++ G Y+FRV A+N+ G+ S P I++ +
Sbjct: 13237 WDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPV 13296
Query: 248 KTKGFAQRDFSEAPKFTQPLAD 269
Q S K+ PL D
Sbjct: 13297 NLTSSDQTQSSVQLKWEPPLKD 13318
Score = 59.7 bits (143), Expect = 4e-09
Identities = 61/221 (27%), Positives = 83/221 (37%), Gaps = 32/221 (14%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ------KADTKSGLW--FT 194
IE PGPP + ++VD S TL W P G ++GY V+ A G W
Sbjct: 18494 IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEG-WKRCN 18552
Query: 195 VLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQ 254
R V+ L Y FRV A+NQ G+ A + +
Sbjct: 18553 AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAEL---------------KEAIKP 18597
Query: 255 RDFSEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
++ E P+ + V G +LF VR P PK+ W K +D N +
Sbjct: 18598 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID---NVVRKGQV 18654
Query: 312 HL--GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L + L I D G Y+ VNP GE +V V V
Sbjct: 18655 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRV 18695
Score = 59.7 bits (143), Expect = 4e-09
Identities = 66/250 (26%), Positives = 94/250 (37%), Gaps = 30/250 (12%)
Query: 114 EAQRADSG-RYQLRVQ----LGGLEATATIDILVIERP-GPPQSIKLVDVWGFSATLEWT 167
+AQ + G Y+ RV +G +A+ + V P PP + + + V TL+WT
Sbjct: 23483 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 23542
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
P G + + GY V+K D G W + T VS L Y FRV A+N G
Sbjct: 23543 KPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG 23602
Query: 227 L-----SETAPITT-DLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQL 280
T PIT D + + S PKF + G +L
Sbjct: 23603 AISKPSDSTGPITAKDEVELPR--------------ISMDPKFRDTI---VVNAGETFRL 23645
Query: 281 FCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
V P P I WL+ +I+ + + L ++ DGG Y +A N G
Sbjct: 23646 EADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 23705
Query: 341 EASVDCRVDV 350
S V V
Sbjct: 23706 SKSFPVNVKV 23715
Score = 59.3 bits (142), Expect = 5e-09
Identities = 46/207 (22%), Positives = 76/207 (36%), Gaps = 17/207 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR--TS 203
P PP + + D + W PP+ G + ++GY V+ + W V +
Sbjct: 14285 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 14344
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
+ ++ Y RV A N G+SE + I+ ++ +D P
Sbjct: 14345 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV---------------VAKDPDCKPTI 14389
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
D + G + RA P P + W K+ +++ + + LE+ K
Sbjct: 14390 DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKS 14449
Query: 324 GPFDGGIYTCKAVNPLGEASVDCRVDV 350
D GIYT N LG A+ V V
Sbjct: 14450 VRADAGIYTITLENKLGSATASINVKV 14476
Score = 59.3 bits (142), Expect = 5e-09
Identities = 56/225 (24%), Positives = 88/225 (39%), Gaps = 30/225 (13%)
Query: 135 TATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT 194
T + I I+RPG P+++ + D L+W P G + L Y V++ S W
Sbjct: 18090 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER 18149
Query: 195 VLE------HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYK 248
V + HY C+ + + Y FRV +N+ G S+ K
Sbjct: 18150 VHKGSIKETHYMVDRCVENQI-----YEFRVQTKNEGGESDWV----------------K 18188
Query: 249 TKGFAQRDFSEAPKFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNK--MDIQGNP 305
T+ ++ + P L+ TV G +L VR P P++ W K+K D+ +P
Sbjct: 18189 TEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP 18248
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + T + K DGG Y A N G V+V
Sbjct: 18249 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 18293
Score = 59.3 bits (142), Expect = 5e-09
Identities = 49/210 (23%), Positives = 78/210 (37%), Gaps = 15/210 (7%)
Query: 133 EATATID-ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
E T T + + E P PP S+ ++D+ + +L W P+ G + + GY ++ S
Sbjct: 20951 EPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 21010
Query: 192 WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKG 251
W T + C+V +L G Y F+V A N G S + Q +G
Sbjct: 21011 W-THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRG 21069
Query: 252 FAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
Q+ G N ++ V P+P + W K ++ + T
Sbjct: 21070 IYQK-------------LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFET 21116
Query: 312 HLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
L I + D G Y A N +GE
Sbjct: 21117 TATSTILNINECVRSDSGPYPLTARNIVGE 21146
Score = 58.9 bits (141), Expect = 7e-09
Identities = 67/299 (22%), Positives = 111/299 (37%), Gaps = 41/299 (13%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRY- 123
VG V L +G +W D + ++ + + E + L + A++G+Y
Sbjct: 7505 VGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYT 7564
Query: 124 -QLRVQLGGLEATATIDIL----VIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALL 178
Q++ G E AT+ +L ++E+P +SIK+ TG+T L
Sbjct: 7565 CQIKNDAGMQECFATLSVLEPATIVEKP---ESIKVT----------------TGDTCTL 7605
Query: 179 GYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAE-NQCGLSETAPITTDL 237
TV S WF + +L N Y F + + + AP + +
Sbjct: 7606 ECTVAGTPELSTKWFKDGK----------ELTSDNKYKISFFNKVSGLKIINVAPSDSGV 7655
Query: 238 AHIQKAATVYK---TKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIW 294
+ V K T D + P FT+ L + ++G + + C V SP + W
Sbjct: 7656 YSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSW 7715
Query: 295 LKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+I KY+ C+L + D G YTC A N G + V+ P
Sbjct: 7716 FHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREP 7774
Score = 58.9 bits (141), Expect = 7e-09
Identities = 52/208 (25%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP + + V S TL+W P G + + GY V+K + G W + T V
Sbjct: 22441 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEV 22500
Query: 207 SDLIIGNSYAFRVFAENQCGL-SETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
+ L+ + Y FRV A N G+ SE + T RD + P+ +
Sbjct: 22501 TGLVEDHRYEFRVIARNAAGVFSEPSE---------------STGAITARDEVDPPRISM 22545
Query: 266 PLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
T+ G + ++ + P P I W+K ++ + + SL ++
Sbjct: 22546 DPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKD 22605
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y KA N GE SV V V
Sbjct: 22606 AVRVDSGNYILKAKNVAGERSVTVNVKV 22633
Score = 58.5 bits (140), Expect = 9e-09
Identities = 51/212 (24%), Positives = 77/212 (36%), Gaps = 35/212 (16%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY 199
I+ E+P PP+ + +VD SA L W P G + + GY ++ S W H
Sbjct: 28540 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHT 28598
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
+ + V L+ Y FRV A+N G SE + F+ E
Sbjct: 28599 KQLTFTVERLVEKTEYEFRVKAKNDAGYSE------------------PREAFSSVIIKE 28640
Query: 260 APKFTQPLADCTTVTGYNTQLFCC-----------VRASPRPKIIWLKNKMDIQGNPKYR 308
+P AD +TG QL C + P PK+ W +M ++ +
Sbjct: 28641 PQ--IEPTAD---LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS 28695
Query: 309 ALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
T +L ++ D G Y N G
Sbjct: 28696 ITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 28727
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/218 (24%), Positives = 81/218 (37%), Gaps = 29/218 (13%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ-----KADTKSGLWFTVLEH-Y 199
P PP +K+ + + L W PP++ G + + Y V+ TK W +
Sbjct: 16012 PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDV 16071
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
V DL+ G Y FRV A N G+S+ + T G +
Sbjct: 16072 EELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS----------------ATVGPCDCQRPD 16115
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-------NKMDIQGNPKYRALTH 312
P G N + ++ P P + W K NK + + L
Sbjct: 16116 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVV 16175
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
C+L I + D G+YT AVN LG AS + R++V
Sbjct: 16176 DDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 16213
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/208 (25%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP K+VD + T+ W P G + GYTV+ + W T ++ T
Sbjct: 26084 PSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYT 26143
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF-- 263
+S L G Y FRV + N+ G S+ +D + Q A ++ E P F
Sbjct: 26144 ISGLTTGAEYVFRVKSVNKVGASD----PSDSSDPQIA-----------KEREEEPLFDI 26188
Query: 264 -TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
++ G + + R P P ++W K D++ + T SL I
Sbjct: 26189 DSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLR--TRAYVDTTDSRTSLTIEN 26246
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G YT N L AS+ V V
Sbjct: 26247 ANRNDSGKYTLTIQNVLSAASLTLVVKV 26274
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/212 (21%), Positives = 86/212 (40%), Gaps = 17/212 (8%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
G+ A + + E+P PP+ + + + S +L W P+ G + ++ Y V+ +
Sbjct: 26360 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 26419
Query: 191 LWF--TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYK 248
W V + H +VS L + Y FRVFAENQ GLS+ + + ++
Sbjct: 26420 NWVKCAVAKSTHH---VVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEP--- 26473
Query: 249 TKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR 308
+ D P T + G N ++ + P PK+ ++ + ++ ++
Sbjct: 26474 ----PEIDMKNFPSHTVYVR-----AGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFN 26524
Query: 309 ALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
++ +++ D G Y A N G
Sbjct: 26525 TEITAENLTINLKESVTADAGRYEITAANSSG 26556
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 10/106 (9%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L++T T+ P PP + D+ +AT+ WT P+ G + + GY +++ + +G
Sbjct: 17690 LDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREV-TGK 17748
Query: 192 WFTVLEHYHRTSCI-----VSDLIIGNSYAFRVFAENQCGLSETAP 232
W V ++T V+ L GN+Y FRVFAEN GLS+ +P
Sbjct: 17749 WVRV----NKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSP 17790
Score = 57.8 bits (138), Expect = 1e-08
Identities = 55/208 (26%), Positives = 79/208 (37%), Gaps = 29/208 (13%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-----TVLE 197
I+ PG P + + + TL+W P+ TG + Y V+K D +G W +LE
Sbjct: 21357 IDPPGKPVPLNITR---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 21413
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
+ S + D +Y FRV A+N G +D RD
Sbjct: 21414 NEFTVSGLTEDA----AYEFRVIAKNAAGAISPPSEPSD--------------AITCRDD 21455
Query: 258 SEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
EAPK + TV G +L V P P + W K+ +++G K
Sbjct: 21456 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 21515
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
+L + D G YT A NP G A
Sbjct: 21516 STNLVNKDSTRRDSGAYTLTATNPGGFA 21543
Score = 56.6 bits (135), Expect = 3e-08
Identities = 60/302 (19%), Positives = 123/302 (40%), Gaps = 38/302 (12%)
Query: 47 IEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGE 105
++E PK + L + + K G+++ L G P+ + W + L ++ + ++
Sbjct: 6360 VKEPPKF--VKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFIN 6417
Query: 106 QDSILFIREAQRADSGRYQLRVQLGGLEATATIDILV------IERPGPPQSIKLVDVWG 159
++L I EA DSG Y G +A+ + + V ++P P ++K DV
Sbjct: 6418 SVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVI- 6476
Query: 160 FSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRV 219
+ TPP + + + + ++ F + + TS + +L + +
Sbjct: 6477 LQCEISGTPPFE------VVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHC 6530
Query: 220 FAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQ 279
A N+ G S+T + F E P+F + L+D +T+ G +
Sbjct: 6531 KATNEVG-SDTCSCSVK--------------------FKEPPRFVKKLSDTSTLIGDAVE 6569
Query: 280 LFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL-GICSLEIRKPGPFDGGIYTCKAVNP 338
L V ++WLK++ ++ + ++ + I +L++ P + G Y C+ N
Sbjct: 6570 LRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKND 6629
Query: 339 LG 340
G
Sbjct: 6630 AG 6631
Score = 56.6 bits (135), Expect = 3e-08
Identities = 46/200 (23%), Positives = 78/200 (39%), Gaps = 17/200 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF--TVLEHYHRTS 203
PGPP + + D SA+L W P G + GY V+ W T T
Sbjct: 20673 PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQ 20732
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
+V DL Y FR+ A N G+ E A + D+ +++ DF +
Sbjct: 20733 FVVPDLQTKEKYNFRISAINDAGVGEPA-VIPDVEIVEREMA---------PDFELDAEL 20782
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
+ L G + ++F ++ P P++ W K+ ++++ + L I +
Sbjct: 20783 RRTL---VVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--LIIPEC 20837
Query: 324 GPFDGGIYTCKAVNPLGEAS 343
+D G + NP G+ S
Sbjct: 20838 NRYDTGKFVMTIENPAGKKS 20857
Score = 56.2 bits (134), Expect = 4e-08
Identities = 74/294 (25%), Positives = 112/294 (38%), Gaps = 32/294 (10%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCALDT---RRVSVRNGEQDSILFIREAQRADSGRY 123
VG+T L G P+ W DG L + + S N + S L I +R D+G Y
Sbjct: 5717 VGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYN--KISSLRILSVERQDAGTY 5774
Query: 124 QLRVQ--LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYT 181
+VQ +G TA +D V +R PP F+ L+ T G + +L
Sbjct: 5775 TFQVQNNVGKSSCTAVVD--VSDRAVPPS---------FTRRLKNTGGV-LGASCILECK 5822
Query: 182 VQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQ 241
V + S WF H + IVS G Y F++N C L + ++D+ +
Sbjct: 5823 VAGSSPISVAWF------HEKTKIVS----GAKYQ-TTFSDNVCTLQLNSLDSSDMGNYT 5871
Query: 242 KAAT--VYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKM 299
A + A E P F + + G N +R +P K+ W +
Sbjct: 5872 CVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGAR 5931
Query: 300 DIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
++ + + LE+ G YTC N G+AS R+ VK P
Sbjct: 5932 ELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEP 5985
Score = 55.8 bits (133), Expect = 6e-08
Identities = 65/289 (22%), Positives = 116/289 (40%), Gaps = 22/289 (7%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQL 125
VG++ + G + W D + + + + E + L + + + DSG+Y
Sbjct: 8166 VGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTC 8225
Query: 126 RV--QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
++G TA ++I ER PP F+ L T + GN+ L V
Sbjct: 8226 YAVNEVGKDSCTAQLNIK--ERLIPPS---------FTKRLSETVEETEGNSFKLEGRVA 8274
Query: 184 KADTKSGLWF-TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQK 242
+ + W+ +E ++C ++ N+ +V + G+++ T +++
Sbjct: 8275 GSQPITVAWYKNNIEIQPTSNCEIT--FKNNTLVLQV---RKAGMNDAGLYTCKVSN--D 8327
Query: 243 AATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ 302
A + T ++ + P F Q L T G QL C V+ S +I WLK +I+
Sbjct: 8328 AGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIK 8387
Query: 303 GNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
+ + G LE+R D G Y CKA N G + +V +K
Sbjct: 8388 PSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIK 8436
Score = 55.8 bits (133), Expect = 6e-08
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTSC 204
PGPP+ ++ +V +AT+ W P D G + + GY V++ + KS W ++ C
Sbjct: 20572 PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 20631
Query: 205 IVSDLIIGNSYAFRVFAENQCGL 227
V+ L G++Y FRV AEN+ G+
Sbjct: 20632 KVTGLQEGSTYEFRVSAENRAGI 20654
Score = 55.1 bits (131), Expect = 1e-07
Identities = 66/305 (21%), Positives = 119/305 (39%), Gaps = 37/305 (12%)
Query: 62 TYIRKV-------GDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIR 113
T+++KV G TV L +G W + + ++ + ++L I
Sbjct: 3925 TFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIP 3984
Query: 114 EAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTG 173
+ Q + G+Y + T+ +++V E + +L+ V G
Sbjct: 3985 DVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKIIERAELIQV-------------TAG 4031
Query: 174 NTALLGYTVQKADTKSGLWFT-----VLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
+ A L YTV W+ V +R S N+ A F + L
Sbjct: 4032 DPATLEYTVAGTPELKPKWYKDGRPLVASKKYRIS-------FKNNVAQLKFYSAE--LH 4082
Query: 229 ETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASP 288
++ T ++++ +++ T RD AP FT+PL + +V +L C + S
Sbjct: 4083 DSGQYTFEISNEVGSSSCETTFTVLDRDI--APFFTKPLRNVDSVVNGTCRLDCKIAGSL 4140
Query: 289 RPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
++ W K+ +I + +YR G SLEI + D G +TC+A N +G +
Sbjct: 4141 PMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL 4200
Query: 349 DVKVP 353
V+ P
Sbjct: 4201 IVQEP 4205
Score = 55.1 bits (131), Expect = 1e-07
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 1/102 (0%)
Query: 253 AQRDFSEAPKFTQPL-ADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
AQ E PKF + L A G + QL C + SP K+ W +N ++ + KY
Sbjct: 6356 AQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSF 6415
Query: 312 HLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ L I + D G Y C+A N +G+AS + VK P
Sbjct: 6416 INSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVKAP 6457
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/223 (25%), Positives = 88/223 (39%), Gaps = 22/223 (9%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
G T + E P P + + + D S L WT P G + + Y V++
Sbjct: 27448 GEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQ 27507
Query: 191 LWFTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKT 249
W +T I VS L + FRVFA+N+ GLS+ P+T +++ +
Sbjct: 27508 TWSHA--GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD--PVTIGPITVKELIITPEV 27563
Query: 250 KGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA 309
D S+ P A T G+N L + P+P I WLK+ + ++ + R
Sbjct: 27564 ------DLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRF 27612
Query: 310 LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
+L I+ GG YT N + CR+ V +
Sbjct: 27613 SKTENKITLSIKNAKKEHGGKYTVILDNAV------CRIAVPI 27649
Score = 54.7 bits (130), Expect = 1e-07
Identities = 57/253 (22%), Positives = 98/253 (38%), Gaps = 33/253 (13%)
Query: 107 DSILFIREAQRADSGRYQLRVQ--LGGLEATATIDI----LVIERPGPPQSIKLVDVWGF 160
+S L + + +DSG Y +V GG+E +A + + +E+ P Q +K D
Sbjct: 4260 ESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQL 4319
Query: 161 SATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVF 220
+ + TPP T K +K + F R ++D+ I +S +
Sbjct: 4320 ACKVTGTPPIKI--TWFANDREIKESSKHRMSFVESTAVLR----LTDVGIEDSGEYMCE 4373
Query: 221 AENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQL 280
A+N+ G + I E+P FT+ + Y+ L
Sbjct: 4374 AQNEAGSDHCSSIVI---------------------VKESPYFTKEFKPIEVLKEYDVML 4412
Query: 281 FCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
V +P +I W K+ ++ KY+ + SL+I K D G Y C+ N +G
Sbjct: 4413 LAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVG 4472
Query: 341 EASVDCRVDVKVP 353
+ RV ++ P
Sbjct: 4473 SSICSARVTLREP 4485
Score = 54.7 bits (130), Expect = 1e-07
Identities = 31/95 (32%), Positives = 44/95 (46%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P F + L V + +L C V +P ++ WLKN +I+ + KY + + +L
Sbjct: 4953 EPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNL 5012
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
I K P D G Y C N G S RV +K P
Sbjct: 5013 HITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEP 5047
Score = 54.7 bits (130), Expect = 1e-07
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 1/97 (1%)
Query: 258 SEAPKFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC 316
+E PKF + L V G +++L C + SP +++W +N+ ++ + KYR +
Sbjct: 5420 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 5479
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+++ D G + C+A NP G S +V VK P
Sbjct: 5480 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEP 5516
Score = 54.7 bits (130), Expect = 1e-07
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 14/159 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ--KADTKSGLWFTVLEHYHRTS 203
PGPP K+ D S +L W P G + ++GY V+ +AD+ + + + ++ +T
Sbjct: 19589 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 19648
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V+ L+ Y FRV+A N+ G S+ + + H K + +G D +
Sbjct: 19649 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPD--KHYPKDILI-PPEGELDADLRKT--- 19702
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ 302
G +L+ V+ P PKI W K ++++
Sbjct: 19703 ------LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLR 19735
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query: 146 PGPPQSI-KLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTS 203
P PP + +++DV S +L W+ P+D G + + GY +++ +T + W + T
Sbjct: 30329 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 30388
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAP 232
V+ L+ Y FR+ A+N GLSET+P
Sbjct: 30389 YTVTGLVPDAEYQFRIIAQNDVGLSETSP 30417
Score = 53.9 bits (128), Expect = 2e-07
Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP+S+++ ++ S T+ W P G + ++GY V+K D +SG+ + T
Sbjct: 23819 PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRD-RSGIRWIKCNKRRITDLR 23877
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
V+ L + Y FRV AEN G+ E +P T
Sbjct: 23878 LRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 23908
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 3/136 (2%)
Query: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTG 275
AF+ E +SET +D + T KT+ A S P L D T +
Sbjct: 32810 AFKSIHEKVSKISETKK--SDQKTTESTVT-RKTEPKAPEPISSKPVIVTGLQDTTVSSD 32866
Query: 276 YNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
+ PRP IW K+ I KY+ G LEI K D G+YTC
Sbjct: 32867 SVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTV 32926
Query: 336 VNPLGEASVDCRVDVK 351
N G S C++ +K
Sbjct: 32927 KNSAGSVSSSCKLTIK 32942
Score = 53.5 bits (127), Expect = 3e-07
Identities = 64/290 (22%), Positives = 111/290 (38%), Gaps = 25/290 (8%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIREAQRADSGRY 123
VGD+ +L G P+ W L T ++ RN + L + DSG Y
Sbjct: 7974 VGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNV--ATLVFNQVDINDSGEY 8031
Query: 124 QLRVQLGGLEATATIDILVIERPGPPQ-SIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
+ + E +A+ + V E+ PP S +L DV + G + +
Sbjct: 8032 ICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDV-----------QETVGLPVVFDCAI 8080
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE-TAPITTDLAHIQ 241
++ S W+ + + S V + N+ +F ++ + + T +
Sbjct: 8081 SGSEPISVSWYKDGKPL-KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSAS 8139
Query: 242 KAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDI 301
+A + T+G P F LA V G + C V + K+ W K+ +I
Sbjct: 8140 SSARLILTEG------KNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREI 8193
Query: 302 QGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
+ KY+ L + K D G YTC AVN +G+ S ++++K
Sbjct: 8194 RSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIK 8243
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Query: 131 GLEATATIDILV---IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADT 187
G + +T IL+ I+ P PP + DV S L WT P+ G + Y ++ T
Sbjct: 13966 GKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKT 14025
Query: 188 KSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ W V E T ++ L+ G Y+FRV A N+ G SE
Sbjct: 14026 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESE 14067
Score = 52.8 bits (125), Expect = 5e-07
Identities = 27/92 (29%), Positives = 41/92 (44%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P L + T + G + L C + P P + W + I+ + ++ GI L I
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
R+ D G +TC AVN G S C + V+V
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 1034
Score = 52.4 bits (124), Expect = 6e-07
Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYN-TQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
AQ E P+F + L V T+ C + SP K++W K++ +IQ + K+R
Sbjct: 7297 AQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSF 7356
Query: 312 HLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ LE+ D G YTC+A N G AS + VK P
Sbjct: 7357 VDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEP 7398
Score = 52.4 bits (124), Expect = 6e-07
Identities = 68/290 (23%), Positives = 102/290 (35%), Gaps = 26/290 (8%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLR 126
GDT L G P+ W DG L + + + + S L I +DSG Y
Sbjct: 7600 GDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFE 7659
Query: 127 VQLGGLEATATIDILVIERPGPPQ-SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
VQ + + T + V +R PP + KL + G S G++ ++ V +
Sbjct: 7660 VQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS-----------GSSVVMECKVYGS 7708
Query: 186 DTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAAT 245
S WF H + I S G Y +N C L+ +D AT
Sbjct: 7709 PPISVSWF------HEGNEISS----GRKYQ-TTLTDNTCALTVNMLEESDSGDYTCIAT 7757
Query: 246 --VYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
+ A E P F Q +TG N V+ +P + W K ++
Sbjct: 7758 NMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVP 7817
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ + LE+ G YTC N G+AS + +K P
Sbjct: 7818 GDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAP 7867
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/211 (25%), Positives = 80/211 (37%), Gaps = 24/211 (11%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
PG P++I + + TL+W P G + + GY V+K D G W + T
Sbjct: 24606 PGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEF 24662
Query: 205 IVSDLIIGNSYAFRVFAENQCG-LSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP-- 261
VS L+ Y FRV A N G SE + + RD +AP
Sbjct: 24663 TVSGLVEDQRYEFRVIARNAAGNFSEPSD---------------SSGAITARDEIDAPNA 24707
Query: 262 KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGN-PKYRALTHLGICSLE 319
D V G L +R P P ++W K+ +++ + + + +L
Sbjct: 24708 SLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLV 24767
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
++ DGG Y K N G S+ V V
Sbjct: 24768 VKDCIRTDGGQYILKLSNVGGTKSIPITVKV 24798
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 9/125 (7%)
Query: 114 EAQRADSG-RYQLRVQLG-------GLEATATIDILVIERPGPPQSIKLVDVWGFSATLE 165
+A R +G YQ RV+ G+ + + + PGPP + ++ V S T+
Sbjct: 21219 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 21278
Query: 166 WTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD-LIIGNSYAFRVFAENQ 224
W P G + +LGY V++ + LW TV + + S L G +Y FRV AEN
Sbjct: 21279 WHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENM 21338
Query: 225 CGLSE 229
G S+
Sbjct: 21339 AGKSK 21343
Score = 50.8 bits (120), Expect = 2e-06
Identities = 30/93 (32%), Positives = 39/93 (41%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P FT+ L ++ G L C V S I W K+ +I + KY+ H LEI
Sbjct: 4675 PSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEI 4734
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ D G YTC A N G + VK P
Sbjct: 4735 SQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEP 4767
Score = 50.8 bits (120), Expect = 2e-06
Identities = 67/279 (24%), Positives = 102/279 (36%), Gaps = 26/279 (9%)
Query: 79 GKPKPQAIWTHDGCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATAT 137
G P+ A W DG L + + + + L I A+ +D G Y V+ ++ T
Sbjct: 6670 GTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCT 6729
Query: 138 IDILVIERPGPPQSI-KLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
+ + V +R PP I KL DV A+LG +V SG +
Sbjct: 6730 VSVHVSDRIVPPSFIRKLKDV-----------------NAILGASVVLECRVSGSAPISV 6772
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQC--GLSETAPITTDLAHIQKAATVYKTKGFAQ 254
+ + IVS +S F+EN C LS P T + A + A
Sbjct: 6773 GWFQDGNEIVSGPKCQSS-----FSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAV 6827
Query: 255 RDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
E P F Q + G + +R +P K+ W K ++
Sbjct: 6828 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 6887
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ LE+ + P + G Y+C N G AS + VK P
Sbjct: 6888 VTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEP 6926
Score = 50.8 bits (120), Expect = 2e-06
Identities = 55/235 (23%), Positives = 82/235 (34%), Gaps = 46/235 (19%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRTSC 204
P PP +++ + + T+ W PP G + ++GY ++K W EH +
Sbjct: 14580 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 14639
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
L G Y FRV AEN G+SE + T + D +APK
Sbjct: 14640 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV---------------DPIDAPKVI 14684
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNK-MDIQGNPKYRALTHLGICSLEIRKP 323
G L + SP P I W+K++ + + K RA + E+++
Sbjct: 14685 L-RTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 14743
Query: 324 GPF----------------------------DGGIYTCKAVNPLGEASVDCRVDV 350
PF D G+Y K N G A C V V
Sbjct: 14744 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 14798
Score = 50.8 bits (120), Expect = 2e-06
Identities = 55/221 (24%), Positives = 84/221 (38%), Gaps = 33/221 (14%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH---YHRT 202
PGPP ++ D S +L W PP G + + GY V+ + + W V E
Sbjct: 15705 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 15764
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDL--AHIQKAATVYKTKGFAQRDFSEA 260
C+V +L Y FRV A N+ G SE + T ++ IQ+ V+ G
Sbjct: 15765 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIG--------- 15815
Query: 261 PKFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIW-----LKNKM-----DIQGNPKYRA 309
DC G ++ ++ P PK W K M DI + +
Sbjct: 15816 ------AQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLET 15869
Query: 310 LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + + K G Y+ A N G+ + +CRV V
Sbjct: 15870 AENSSVIIIPECKRS--HTGKYSITAKNKAGQKTANCRVKV 15908
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 20/211 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR- 201
I PGPP K+ D SA LEW+PP G + + GY V+ + W + R
Sbjct: 16419 IAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 16477
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
T +V+ L G Y FRV A N G+ E + TD+ ++ R S
Sbjct: 16478 TKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEV-TDVIEMK------------DRLVSPDL 16524
Query: 262 KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI-CSLE 319
+ + D V G ++ V P P + W N+ + P+ + I S+
Sbjct: 16525 QLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL---PQEATIETTAISSSMV 16581
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I+ G+Y+ A N GE VDV
Sbjct: 16582 IKNCQRSHQGVYSLLAKNEAGERKKTIIVDV 16612
Score = 50.8 bits (120), Expect = 2e-06
Identities = 52/206 (25%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PGPP+ + VDV +L W P G + + GY V+ + + W + C+
Sbjct: 17410 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECV 17468
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
V+ L G +Y FRV AEN GL P TT Q ++ + +
Sbjct: 17469 VTGLQQGKTYRFRVKAENIVGLG--LPDTTIPIECQ------------EKLVPPSVELDV 17514
Query: 266 PLADCTTVTGYNTQLF-CCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
L + V T F +R P P W + +I+ + Y T L I+
Sbjct: 17515 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCL 17574
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y N G +V + V
Sbjct: 17575 RRDTGEYQITVSNAAGSKTVAVHLTV 17600
Score = 50.8 bits (120), Expect = 2e-06
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
P PP S+++ V S TL W+ P+ G + + GY +++ + S W V + +
Sbjct: 25983 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 26042
Query: 205 IVSDLIIGNSYAFRVFAENQCGL---SETAPI 233
+ L G Y +RV+AEN GL SET+P+
Sbjct: 26043 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL 26074
Score = 50.4 bits (119), Expect = 2e-06
Identities = 72/304 (23%), Positives = 116/304 (38%), Gaps = 38/304 (12%)
Query: 64 IRKVGDTVNLLIPFQ----GKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRA 118
+R V +TV L + F G W DG L D+ V + + L I + R+
Sbjct: 8063 LRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRS 8122
Query: 119 DSGRYQLRVQLGGLEATATIDILVIERPGPPQ-SIKLVDV---WGFSATLEWTPPQDTGN 174
+G+Y A+++ +++ E PP I+L V G SA E TG
Sbjct: 8123 LAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFEC---HVTGT 8179
Query: 175 TAL-LGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPI 233
+ + + + +SG + + + V + G+S + +A N+ G
Sbjct: 8180 QPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVG------- 8232
Query: 234 TTDLAHIQKAATVYKTKGFAQRDFSEA---PKFTQPLADCTTVT-GYNTQLFCCVRASPR 289
K AQ + E P FT+ L++ T G + +L V S
Sbjct: 8233 --------------KDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQP 8278
Query: 290 PKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVD 349
+ W KN ++IQ L++RK G D G+YTCK N G A +
Sbjct: 8279 ITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIV 8338
Query: 350 VKVP 353
+K P
Sbjct: 8339 IKEP 8342
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PGPP + + +V S T+ W P G +A++GY ++ D S LW + RT+
Sbjct: 26670 PGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHF 26729
Query: 206 -VSDLIIGNSYAFRVFAENQCGLSE 229
V+ + G Y FRV+AEN G+ +
Sbjct: 26730 KVTTISAGLIYEFRVYAENAAGVGK 26754
Score = 49.7 bits (117), Expect = 4e-06
Identities = 27/85 (31%), Positives = 36/85 (42%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P F L G + L C V +P + W K ++ P+YR + +L
Sbjct: 6077 EPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATL 6136
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEAS 343
K D G YTCKA N +G AS
Sbjct: 6137 VFNKVNINDSGEYTCKAENSIGTAS 6161
Score = 49.7 bits (117), Expect = 4e-06
Identities = 29/93 (31%), Positives = 41/93 (44%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P F +PL V G L C V +P +I W K ++ P Y+ + SL
Sbjct: 7018 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 7077
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
I K D G Y+CKA N +G + + +K
Sbjct: 7078 VINKVDHSDVGEYSCKADNSVGAVASSAVLVIK 7110
Score = 49.7 bits (117), Expect = 4e-06
Identities = 54/223 (24%), Positives = 89/223 (39%), Gaps = 27/223 (12%)
Query: 137 TIDILVIERP----GPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
T + LVI P P+ +++ +V + TL W PP+ G + ++ Y ++ + +
Sbjct: 16704 TSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 16763
Query: 193 FTVL-EHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE----TAPITTDLAHIQKAATVY 247
V ++ V L G++Y +RV A N G + T PIT K
Sbjct: 16764 HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITC------KDELAP 16817
Query: 248 KTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKY 307
T RD K T + + +TG + P+PK+ W K++ D+ + +
Sbjct: 16818 PTLHLDFRD-----KLTIRVGEAFALTGRYS-------GKPKPKVSWFKDEADVLEDDRT 16865
Query: 308 RALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
T +LE K D G Y N G C+V+V
Sbjct: 16866 HIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 16908
Score = 49.7 bits (117), Expect = 4e-06
Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 11/90 (12%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV------L 196
I PGPP+++++ DV TL W PP+D G + + GY V++ + ++ W V +
Sbjct: 29929 IRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTM 29988
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
Y T L G Y RV A N G
Sbjct: 29989 TRYRSTG-----LTEGLEYEHRVTAINARG 30013
Score = 49.3 bits (116), Expect = 5e-06
Identities = 79/345 (22%), Positives = 126/345 (36%), Gaps = 35/345 (10%)
Query: 15 LKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLL 74
L++ A D+ + AGS + + E P + + +Y+ G++ L
Sbjct: 3701 LEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSF--VKKVDPSYLMLPGESARLH 3758
Query: 75 IPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLE 133
+G P Q W + L ++ V + ++IL I + + DSG Y
Sbjct: 3759 CKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGS 3818
Query: 134 ATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDT--GNTALLGYTVQKADTKSGL 191
+ + +I++ E PP IK TLE P D G ALL V
Sbjct: 3819 DSCSTEIVIKE---PPSFIK---------TLE---PADIVRGTNALLQCEVSGTGPFEIS 3863
Query: 192 WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITT-DLAHIQ--KAATVYK 248
WF + I +S +R+F++ E + D+ + A V K
Sbjct: 3864 WFKDKKQ------------IRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGK 3911
Query: 249 TKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR 308
A E P F + + D + G L VR S + W+K + I+ + K +
Sbjct: 3912 CGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIK 3971
Query: 309 ALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
G+ L I GG YTC A N G + + VK P
Sbjct: 3972 MSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEP 4016
Score = 49.3 bits (116), Expect = 5e-06
Identities = 51/209 (24%), Positives = 80/209 (38%), Gaps = 17/209 (8%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY-TVQKADTKSGLWFTVLEHYHR 201
+ P PP+ +++ ++ SATL W PP G + GY T + + + +T
Sbjct: 18796 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD 18855
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
S +V+ L G Y FRV A N G+S ++A VY+ K + P
Sbjct: 18856 LSLVVTGLKEGKKYKFRVAARNAVGVSLP----------REAEGVYEAK-----EQLLPP 18900
Query: 262 KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIR 321
K P T G ++ V P P W K + ++ + L I+
Sbjct: 18901 KILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 18959
Query: 322 KPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y+ A N G + +V V
Sbjct: 18960 DVTRKDSGYYSLTAENSSGTDTQKIKVVV 18988
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP + ++ + S + W P D G T + GY ++K D K G+ +T T
Sbjct: 24902 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRD-KEGVRWTKCNKKTLTDLR 24960
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSE 229
V+ L G+SY FRV AEN G+ E
Sbjct: 24961 LRVTGLTEGHSYEFRVAAENAAGVGE 24986
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
A I V + PG P+ + G S TL W P+ G + + Y +++ + KS W V
Sbjct: 28145 AQIQYTVPDAPGIPEPSNIT---GNSITLTWARPESDGGSEIQQYILERREKKSTRWVKV 28201
Query: 196 LEH--YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
+ T V+ L GN Y F V AEN G+ + I+
Sbjct: 28202 ISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGIS 28242
Score = 49.3 bits (116), Expect = 5e-06
Identities = 58/232 (25%), Positives = 90/232 (38%), Gaps = 57/232 (24%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK---ADTKSGLW----FTV 195
++ PG P+ + DV + +L W+ P G + ++GY +++ ++ G W +T+
Sbjct: 28939 VDAPGRPE---VTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTI 28995
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL-----SETAPITTDLAHIQKAATVYKTK 250
+ T +S+ G++Y FRV A+N G+ T P+T
Sbjct: 28996 VSDNFFTVTALSE---GDTYEFRVLAKNAAGVISKGSESTGPVTC--------------- 29037
Query: 251 GFAQRDFSEAPKF---TQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLK--------NK 298
RD PK + D T+ G + L V P PKIIW K K
Sbjct: 29038 ----RDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK 29093
Query: 299 MDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ +Q K RA + C D G YT N G +V V V
Sbjct: 29094 VSLQYTGK-RATAVIKFCDRS-------DSGKYTLTVKNASGTKAVSVMVKV 29137
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/214 (25%), Positives = 84/214 (39%), Gaps = 25/214 (11%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV--QKAD----TKSGLWFTVL 196
I PG PQ+ ++ D S +L W+ P+D G + + GY + QK D TK T +
Sbjct: 30030 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 30089
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRD 256
Y ++ L G Y FRV A N G E A + TV T+ D
Sbjct: 30090 REY-----TLTHLPQGAEYRFRVLACNAGGPGEPAEV---------PGTVKVTEMLEYPD 30135
Query: 257 FSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC 316
+ ++ + + G +L ++ P P W K DI + + T
Sbjct: 30136 YELDERYQEGI---FVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHT 30190
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I++ D G Y N G+ +V +V V
Sbjct: 30191 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 30224
Score = 48.9 bits (115), Expect = 7e-06
Identities = 68/316 (21%), Positives = 122/316 (38%), Gaps = 44/316 (13%)
Query: 35 GAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIW---THDG 91
G+ S T LL + E PK + L + I K GD+ L G P+ + +W H+
Sbjct: 5409 GSDSCTTMLL--VTEPPKF--VKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHEL 5464
Query: 92 CALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPG---- 147
A D R++ + +++ + DSG + Q + + ++V E P
Sbjct: 5465 PASDKYRMTFIDSV--AVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSF 5522
Query: 148 PP--QSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PP +++K +V L TPP + + + K +S + + TS
Sbjct: 5523 PPIVETLKNAEV-SLECELSGTPPFE------VVWYKDKRQLRSSKKYKIASKNFHTSIH 5575
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
+ ++ + + A+N+ G S+T T L E P+F
Sbjct: 5576 ILNVDTSDIGEYHCKAQNEVG-SDTCVCTVKL--------------------KEPPRFVS 5614
Query: 266 PLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL-GICSLEIRKPG 324
L T V G +L + + + WLK K ++ + +T + + +L+ K
Sbjct: 5615 KLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAE 5674
Query: 325 PFDGGIYTCKAVNPLG 340
P + G Y C+ N G
Sbjct: 5675 PANAGKYICQIKNDGG 5690
Score = 48.9 bits (115), Expect = 7e-06
Identities = 26/93 (27%), Positives = 45/93 (48%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P FTQ + + G + L C + +P +++W+K++ ++ + K++ + SL I
Sbjct: 6458 PVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHI 6517
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D G Y CKA N +G + C V K P
Sbjct: 6518 LNLEASDVGEYHCKATNEVGSDTCSCSVKFKEP 6550
Score = 48.9 bits (115), Expect = 7e-06
Identities = 54/270 (20%), Positives = 106/270 (39%), Gaps = 36/270 (13%)
Query: 79 GKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATAT 137
G P+ + +W D + ++ + + + ++L + DSG Y A+++
Sbjct: 7331 GSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSS 7390
Query: 138 IDILVIE------RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
+ V E +P P +++K DV L+ TPP + + K + +SG
Sbjct: 7391 TSLKVKEPPIFRKKPHPIETLKGADVH-LECELQGTPPFH------VSWYKDKRELRSGK 7443
Query: 192 WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKG 251
+ ++ TS + ++ + E QC + T + I A
Sbjct: 7444 KYKIMSENFLTSIHILNVDAAD------IGEYQCKATNDVGSDTCVGSIALKAP------ 7491
Query: 252 FAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
P+F + L+D +TV G QL + + ++W K+K +I ++
Sbjct: 7492 ---------PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWIS 7542
Query: 312 HL-GICSLEIRKPGPFDGGIYTCKAVNPLG 340
+ I +L+ + P + G YTC+ N G
Sbjct: 7543 YSENIATLQFSRVEPANAGKYTCQIKNDAG 7572
Score = 48.9 bits (115), Expect = 7e-06
Identities = 52/211 (24%), Positives = 76/211 (36%), Gaps = 22/211 (10%)
Query: 145 RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ--KADTKSGLWFTVLEHYHRT 202
+PGPP + +VD S TL W P G + +LGY V+ KAD + T T
Sbjct: 23919 KPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVT 23978
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+S L Y RV A N+ GL E + + D EAP+
Sbjct: 23979 RFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTV---------------KPEDKLEAPE 24023
Query: 263 F---TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
++ G + ++ + P P+I W + + + K + + L
Sbjct: 24024 LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLS 24081
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I D G Y K N G S V V
Sbjct: 24082 IDNCDRNDAGKYILKLENSSGSKSAFVTVKV 24112
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/221 (25%), Positives = 87/221 (39%), Gaps = 22/221 (9%)
Query: 140 ILVIERPGPPQS---IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
IL ++ GPP S + + + TL+W P+ G + + GY ++K + V
Sbjct: 15286 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 15345
Query: 197 EHY-HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR 255
+ TS +V +L Y FRV A N+ G SE + + + K + +
Sbjct: 15346 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG 15405
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
D + K +P+ VTG P PKI W KN+ I+ +T +
Sbjct: 15406 DTIKV-KAGEPVHIPADVTGL-----------PMPKIEWSKNETVIEKPTDALQITKEEV 15453
Query: 316 ------CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I K D G YT A N LG + V+V
Sbjct: 15454 SRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 15494
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 123 YQLRV-------QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNT 175
YQ R+ Q LE+ + + PGPP + + S ++W P + G +
Sbjct: 23393 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 23452
Query: 176 ALLGYTVQKADTKSGLWFTVLEH-YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
++GY +++ + S LW V + H T +L G Y FRV+AEN G+ + +
Sbjct: 23453 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKAS 23509
Score = 47.8 bits (112), Expect = 2e-05
Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTSC 204
PGPP ++ D+ + TL W P D G + + GY V++ D + W + T+
Sbjct: 13883 PGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTY 13942
Query: 205 IVSDLIIGNSYAFRVFAENQCG 226
V L Y FRV AEN G
Sbjct: 13943 RVKGLTNKKKYRFRVLAENLAG 13964
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 18/119 (15%)
Query: 123 YQLRVQLG---GLEATATIDILVIER----PGPPQSIKLVDVWGFSATLEWTPPQDTGNT 175
YQ RV+ G+ I+V + PGPP + +V +L W P G +
Sbjct: 27727 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 27786
Query: 176 ALLGYTVQKADTKSGLWFTVLEHYHRTSCI------VSDLIIGNSYAFRVFAENQCGLS 228
+ G+ V+K + S LW V TS I + L+ G Y FRV+AEN GLS
Sbjct: 27787 EVTGFHVEKKERNSILWQKV-----NTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 27840
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 37/89 (41%)
Query: 255 RDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
++ S+AP F G N C + P P+I W KN + I +
Sbjct: 33128 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN 33187
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEAS 343
+ SLEIR D G YT KA N G+ S
Sbjct: 33188 VYSLEIRNASVSDSGKYTIKAKNFRGQCS 33216
Score = 47.4 bits (111), Expect = 2e-05
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 3/89 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH--YHRTS 203
P P + +V SA + W P D G + Y ++K +T S W V + + T
Sbjct: 17012 PDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTK 17070
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAP 232
V DL+ G Y FRV AEN+ G+ + +P
Sbjct: 17071 FRVPDLLEGCQYEFRVSAENEIGIGDPSP 17099
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRT 202
++PG P ++ V T+ W PP+ G ++ GY ++K + S W V +
Sbjct: 18394 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPER 18453
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSE 229
V +L+ + Y FRV AEN+ G+ E
Sbjct: 18454 RMKVQNLLPDHEYQFRVKAENEIGIGE 18480
Score = 47.0 bits (110), Expect = 3e-05
Identities = 50/215 (23%), Positives = 76/215 (35%), Gaps = 30/215 (13%)
Query: 145 RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW--FTVLEHYHRT 202
+PGPP + +++D S ++ W P G + + GY V+ A + W T T
Sbjct: 21755 KPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT 21814
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
S ++ L Y R++A N GL E A V T R +
Sbjct: 21815 SYTITGLTENQEYKIRIYAMNSEGLGE-------------PALVPGTPKAEDRMLPPEIE 21861
Query: 263 FTQPLADCTTVTGYNT-QLFCCVRASPRPKIIWLK------NKMDIQGNPKYRALTHLGI 315
L T+ T +LF ++ P P++ W + +K I+ Y L
Sbjct: 21862 LDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI---- 21917
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ FD G Y N G S V V
Sbjct: 21918 ----VGNVNRFDSGKYILTVENSSGSKSAFVNVRV 21948
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
PGPP ++ +VDV L+W PP++ G + Y ++K + W + +
Sbjct: 14184 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 14243
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
V+D+I G F+V AEN+ G+ + T L+
Sbjct: 14244 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILS 14277
Score = 46.2 bits (108), Expect = 4e-05
Identities = 25/95 (26%), Positives = 45/95 (47%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P F + T+ G + L C ++ +P + W K+K +++ KY+ ++ + S+
Sbjct: 7397 EPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSI 7456
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
I D G Y CKA N +G + + +K P
Sbjct: 7457 HILNVDAADIGEYQCKATNDVGSDTCVGSIALKAP 7491
Score = 46.2 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 73/206 (35%), Gaps = 15/206 (7%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF---TVLEHYHRTSC 204
PP +++DV + +L W P+ G + ++GY V+ W T +
Sbjct: 19192 PPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 19251
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
+ L Y FR A +S + + + T+ + D S A K
Sbjct: 19252 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPV-------TILAENVPPRIDLSVAMKSL 19304
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
T G N L V P P + W K+ ++ + +C+LE+
Sbjct: 19305 -----LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVN 19359
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDV 350
D G YT A N G S ++ V
Sbjct: 19360 RKDSGDYTITAENSSGSKSATIKLKV 19385
Score = 46.2 bits (108), Expect = 4e-05
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
P P++ ++ V S + W P G + +LGY ++K D + W +
Sbjct: 22737 PDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRL 22796
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAP 232
V+ LI + Y FRV AEN GLSE +P
Sbjct: 22797 RVTGLIENHDYEFRVSAENAAGLSEPSP 22824
Score = 45.8 bits (107), Expect = 6e-05
Identities = 27/95 (28%), Positives = 43/95 (45%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P+ Q L T +G + + P+PKI W K + + K + L +L
Sbjct: 3237 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3296
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ + P D +YTC+A N G A+ + V+VP
Sbjct: 3297 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP 3331
Score = 45.8 bits (107), Expect = 6e-05
Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 13/121 (10%)
Query: 120 SGRYQLRVQLG---GLEATATIDILVIERP----GPPQSIKLVDVWGFSATLEWTPPQDT 172
+G+Y+ RV+ G+ D +VI+ P GPP K++ S + WTPP D
Sbjct: 15566 NGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDN 15625
Query: 173 GNTALLGYTVQKADTKSGLWFTVLE------HYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
G + + GY ++K + S W V V L+ G Y FR A N G
Sbjct: 15626 GGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAG 15685
Query: 227 L 227
+
Sbjct: 15686 I 15686
Score = 45.8 bits (107), Expect = 6e-05
Identities = 48/207 (23%), Positives = 76/207 (36%), Gaps = 18/207 (8%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS 203
+ PGP +K+ V S ++ W P G + ++GY V T+ W V++
Sbjct: 19882 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL-SLQ 19939
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
DL G Y FRV AEN+ G + IT +A A KG
Sbjct: 19940 YSAKDLTEGKEYTFRVSAENENGEGTPSEITV-VARDDVVAPDLDLKGL----------- 19987
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
P N +L ++ P P + W K + + + + + +L +
Sbjct: 19988 --PDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDC 20045
Query: 324 GPFDGGIYTCKAVNPLG--EASVDCRV 348
D G YT N G E ++ +V
Sbjct: 20046 QKSDAGKYTITLKNVAGTKEGTISIKV 20072
Score = 45.4 bits (106), Expect = 8e-05
Identities = 29/93 (31%), Positives = 40/93 (43%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P FT+ L V G + + C V S W K+ +I + KYR + H SLE+
Sbjct: 5237 PSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEV 5296
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D YTCK N G+ + + VK P
Sbjct: 5297 NNLELEDTANYTCKVSNVAGDDACSGILTVKEP 5329
Score = 45.4 bits (106), Expect = 8e-05
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY--HRTS 203
P PP + V ++WT P+ G + Y V K + KS W V + Y + T
Sbjct: 29240 PSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTR 29299
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSE 229
V+ L+ G Y FRV A N G SE
Sbjct: 29300 LKVTSLMEGCDYQFRVTAVNAAGNSE 29325
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 5/171 (2%)
Query: 61 QTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRR---VSVRNGEQDSILFIREAQR 117
Q+ + G T G P P+ W DG + T V + + + L I +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERPGPPQSI-KLVDVWGFSATLEWTPPQDTG-NT 175
A+SGRY L+ G +AT+T ++LV PP + +L + + + TG T
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT 132
Query: 176 ALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
++ + A+ +S L F + + S ++++ +S + V A N G
Sbjct: 133 PVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Score = 45.1 bits (105), Expect = 1e-04
Identities = 58/288 (20%), Positives = 117/288 (40%), Gaps = 20/288 (6%)
Query: 79 GKPKPQAIWTHDGCALDT--RRVSVRNGEQDSILFIREAQRADSGRY--QLRVQLGGLEA 134
G+P+P+ W + L T + + +G++ ++L I EA D+ Y + + G
Sbjct: 3264 GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI-EAFPEDAAVYTCEAKNDYGVATT 3322
Query: 135 TATIDILVIERPGPPQSIK-----LVDVWGFSATLEWTPPQD----TGNTALLGYTVQKA 185
+A++ + V E P Q + ++ + T E P + +G + + +
Sbjct: 3323 SASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDK 3382
Query: 186 DTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG-LSETAPITTDLAHIQKAA 244
K +F + + +++ + + A N G +S TA ++ + ++
Sbjct: 3383 KIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP---ESI 3439
Query: 245 TVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN 304
+ + + + AP + + G+ + C ++++P + W K +I +
Sbjct: 3440 LHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYES 3499
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
K + I SLEI + D G YTCKA N G SV C + V
Sbjct: 3500 DKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYG--SVSCTATLTV 3545
Score = 45.1 bits (105), Expect = 1e-04
Identities = 62/309 (20%), Positives = 108/309 (34%), Gaps = 28/309 (9%)
Query: 48 EEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQ 106
E +P +L R T VG + G P + IW DG AL + + + E
Sbjct: 3547 EAYPPTFLSRPKSLTTF--VGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAEN 3604
Query: 107 DSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLV-DVWGFSATLE 165
IL + D G Y + ++++I++P + ++ V LE
Sbjct: 3605 KHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLE 3664
Query: 166 WTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQC 225
+D T QK G + + + + + +S + A N+
Sbjct: 3665 CQVDEDRKVTVTWSKDGQK--LPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEA 3722
Query: 226 GLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPL-ADCTTVTGYNTQLFCCV 284
G S + T E P F + + + G + +L C +
Sbjct: 3723 GSSSCSATVT---------------------VREPPSFVKKVDPSYLMLPGESARLHCKL 3761
Query: 285 RASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASV 344
+ SP ++ W KN ++ + R L+I D G Y+C+AVN +G S
Sbjct: 3762 KGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSC 3821
Query: 345 DCRVDVKVP 353
+ +K P
Sbjct: 3822 STEIVIKEP 3830
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 9/106 (8%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
LE+ + + P PP++ ++ + S + W P G + ++ Y V++ D
Sbjct: 21641 LESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQR 21700
Query: 192 WF-----TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAP 232
W T+ + ++ VS L G+ Y FR+ AEN G+S +P
Sbjct: 21701 WIKCNKKTLTDLRYK----VSGLTEGHEYEFRIMAENAAGISAPSP 21742
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/152 (26%), Positives = 62/152 (40%), Gaps = 18/152 (11%)
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
S I+ +S + V A+N+ G S + I T A ++ K P
Sbjct: 1514 SLIIVPATPSDSGEWTVVAQNRAGRSSISVILT------VEAVEHQVK----------PM 1557
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN--PKYRALTHLGICSLEI 320
F + L + G ++ +P P I+WLKN I + PK R G +L+I
Sbjct: 1558 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKI 1617
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
D YT A+N G + C+V+V+V
Sbjct: 1618 DSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649
Score = 44.7 bits (104), Expect = 1e-04
Identities = 56/293 (19%), Positives = 111/293 (37%), Gaps = 32/293 (10%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLR 126
G ++ L + G W DG + T + ++ E+ IL I + + D+G+Y
Sbjct: 6000 GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCE 6059
Query: 127 VQLGGLEATATIDILVIERPGPPQSIKLVD----VWGFSATLEWTPPQDTGNTALLGYTV 182
++ EA + ++ PP + ++ G S +L+ T + +
Sbjct: 6060 IEN---EAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQC----QVAGTPEITVSW 6112
Query: 183 QKADTKSGLWFTVLEHYHRT--SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHI 240
K DTK ++ + + + + I +S + AEN G + + +
Sbjct: 6113 YKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTV------- 6165
Query: 241 QKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMD 300
F ++ P F + L D G L C + S ++ W ++ +
Sbjct: 6166 -----------FRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVL 6214
Query: 301 IQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
++ + + + +L+I + G Y+C A NPLG AS R+ + P
Sbjct: 6215 LRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREP 6267
Score = 44.3 bits (103), Expect = 2e-04
Identities = 26/95 (27%), Positives = 43/95 (45%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P F+ T+ L C + +P +++W K+K ++ + KY+ + S+
Sbjct: 5515 EPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSI 5574
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
I D G Y CKA N +G + C V +K P
Sbjct: 5575 HILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEP 5609
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
P P + DV S ++W P+D G+ +LGY ++K + S W V + +
Sbjct: 14903 PDAPDKPIVEDVTSNSMLVKWNEPKDNGSP-ILGYWLEKREVNSTHWSRVNKSLLNALKA 14961
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAP 232
V L+ G +Y FRV AEN G + +P
Sbjct: 14962 NVDGLLEGLTYVFRVCAENAAGPGKFSP 14989
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 133 EATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
E++A + PGPP + K+V + + W P + G + ++GY ++ + S LW
Sbjct: 25574 ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILW 25633
Query: 193 FTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ T VS L G Y +RV+AEN G+ +
Sbjct: 25634 SKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGK 25671
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/208 (22%), Positives = 81/208 (38%), Gaps = 22/208 (10%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP ++ ++ S +L+W+ P G + GY V++ + G W + T V
Sbjct: 25687 PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEV 25746
Query: 207 SDLIIGNSYAFRVFAENQC-GLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
++L Y FRVFA N +SE + T + +D E P+
Sbjct: 25747 TELTEDQRYEFRVFARNAADSVSEPSESTGPI---------------IVKDDVEPPRVMM 25791
Query: 266 PL--ADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ D V G ++ + P P I W K+ ++I+ + ++ L ++
Sbjct: 25792 DVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKD 25851
Query: 323 PGPFDGGIYTCKAVNPLGEAS--VDCRV 348
D G Y N G S V+C+V
Sbjct: 25852 CIRRDTGQYVLTLKNVAGTRSVAVNCKV 25879
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PG P + V S T+ W P+ G + + GY ++ DT S W V + +
Sbjct: 16317 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 16376
Query: 206 -----VSDLIIGNSYAFRVFAENQCGL 227
V+ LI G+ Y FRV+A N G+
Sbjct: 16377 GVSYKVTGLIEGSDYQFRVYAINAAGV 16403
Score = 43.5 bits (101), Expect = 3e-04
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 8/129 (6%)
Query: 233 ITTDLAHIQKAA--------TVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCV 284
+ TDL+H + + T + R+ ++P F + G + C V
Sbjct: 6235 LQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHV 6294
Query: 285 RASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASV 344
+ +I W K+ +I+ Y L I K G D G YTC+A N +G+
Sbjct: 6295 TGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMC 6354
Query: 345 DCRVDVKVP 353
++ VK P
Sbjct: 6355 SAQLSVKEP 6363
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/216 (25%), Positives = 80/216 (37%), Gaps = 30/216 (13%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRT 202
I PGPP ++ D + LEW PP G ++GY V K + W E +
Sbjct: 15000 ISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKV 15058
Query: 203 -SCIVSDLIIGNSYAFRVFAENQCG---LSETAPITTDLAHIQKAATV---YKTKGFAQR 255
V ++ G Y RV A N G ET P+T +A Q+ V KG Q
Sbjct: 15059 RQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVT--VAEPQEPPAVELDVSVKGGIQ- 15115
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
+ G ++ V P P +W K + ++ + + ++G
Sbjct: 15116 ----------------IMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRV--VIDNVGT 15157
Query: 316 CS-LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
S L I+ D G Y A N G RV+V
Sbjct: 15158 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 15193
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 248 KTKGFAQRDFS--EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNP 305
K + +Q+ F+ AP+ T + G NT+ V++ P ++ W N +++Q +
Sbjct: 32359 KYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS 32418
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
K G+ +LEI D G Y N GEAS +DV
Sbjct: 32419 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L++ A I + PGPP + + + ++W P + G T ++GY +++ + S L
Sbjct: 24491 LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 24550
Query: 192 WFTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
W + + T + L G Y F+V AEN G+ + + ++
Sbjct: 24551 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVS 24594
Score = 42.7 bits (99), Expect = 5e-04
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL++ + + P P +VDV S +L WT P+ TG + + GY ++ + S
Sbjct: 20161 GLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSL 20220
Query: 191 LWFTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSE 229
LW + R V+ L G Y FRV A N G+ +
Sbjct: 20221 LWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGK 20260
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)
Query: 248 KTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ---GN 304
K + R P+FT PL + T G N + + P P + W K+ I+ +
Sbjct: 31677 KRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDND 31736
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
KY + G+ L I D YT A N GE S ++ V
Sbjct: 31737 KKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR-TSC 204
P P++ ++ V + W P G + ++GY +++ + S LW + R T
Sbjct: 19092 PSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEY 19151
Query: 205 IVSDLIIGNSYAFRVFAENQCGLS 228
+ L+ G Y+FR++A N+ G S
Sbjct: 19152 PCAGLVEGLEYSFRIYALNKAGSS 19175
Score = 41.6 bits (96), Expect = 0.001
Identities = 49/211 (23%), Positives = 75/211 (35%), Gaps = 26/211 (12%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL--EHYHRTS 203
PGPP + K+ D S +L W+ P G + GY V+ + + W T
Sbjct: 25003 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 25062
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V+ L Y FR+ A N G+ E A + + ++ E P+
Sbjct: 25063 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERI---------------EPPEI 25107
Query: 264 TQPLADCTTV----TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AD V +LF ++ P P++ W K + + + + L
Sbjct: 25108 ELD-ADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLV 25164
Query: 320 IRKPGPFDGGIYTCKAVNPLGE--ASVDCRV 348
I FD G Y N G A V+ RV
Sbjct: 25165 IDNVTRFDSGRYNLTLENNSGSKTAFVNVRV 25195
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 13/100 (13%)
Query: 141 LVIERPG-PPQSIKLVDVWGFSA---TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
++ E P PP + +V+ SA ++ W P G + ++GY V+K + + LW
Sbjct: 28832 IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWV--- 28888
Query: 197 EHYHRTSCI-----VSDLIIGNSYAFRVFAENQCGLSETA 231
++ C+ V+ L+ G Y FR +A N G+S+ +
Sbjct: 28889 -KENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 28927
Score = 40.4 bits (93), Expect = 0.002
Identities = 39/169 (23%), Positives = 59/169 (34%), Gaps = 9/169 (5%)
Query: 173 GNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
G+ A +Q A WF E Y C + +S CG T
Sbjct: 3470 GHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCG-EYTC 3528
Query: 232 PITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPK 291
+ + + AT+ T+ + P F TT G + C V +P +
Sbjct: 3529 KASNEYGSVSCTATLTVTEAYP-------PTFLSRPKSLTTFVGKAAKFICTVTGTPVIE 3581
Query: 292 IIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
IW K+ + +P +R LE+ D G+Y+CKA N G
Sbjct: 3582 TIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFG 3630
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 236 DLAHIQKAATVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIW 294
D +Q A +KT A E P +FT+PL D T G L C V + K+ W
Sbjct: 12261 DAGEVQLTAKDFKTH--ANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKW 12317
Query: 295 LKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
KN +I + KY + + L I P D YTC A + C ++V P+
Sbjct: 12318 FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA----KDFKTSCNLNVVPPH 12373
Score = 39.7 bits (91), Expect = 0.004
Identities = 61/286 (21%), Positives = 102/286 (35%), Gaps = 47/286 (16%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDG---CALDTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
G + G PK + W DG A+ +S +G + I A+ +SG Y
Sbjct: 4876 GQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGL--ATFQISGARVENSGTYV 4933
Query: 125 LRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFS-----ATLEWTPPQDTGNTALLG 179
+ A+ +I++ V E P + +K V+V +S + TPP + +
Sbjct: 4934 CEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFE------VT 4987
Query: 180 YTVQKADTKSGLWFTVLE-----HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
+ + +S +T+ + + H T C SD E QC +S
Sbjct: 4988 WLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDT-----------GEYQCIVSNEGGSC 5036
Query: 235 TDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIW 294
+ + E P F + + + TTV + V SP I W
Sbjct: 5037 SCSTRVA---------------LKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITW 5081
Query: 295 LKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
LK+ + + + +L+IR G YTC+A N G
Sbjct: 5082 LKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESG 5127
Score = 39.7 bits (91), Expect = 0.004
Identities = 55/285 (19%), Positives = 107/285 (37%), Gaps = 22/285 (7%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+ G + L + G P W D + + R S+ E+ +IL I E+ D +Y
Sbjct: 6939 ETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYS 6998
Query: 125 LRVQLGGLEATATIDILVIERPGPPQSIKLVD-VWGFSATLEWTPPQDTGNTALLGYTVQ 183
++ + + V+E P + ++ V+ V G ATL+ D + + +
Sbjct: 6999 CLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKV--DGTPEIRISWYKE 7056
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
+S + + + S +++ + + + A+N G A A
Sbjct: 7057 HTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVG-----------AVASSA 7105
Query: 244 ATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
V K + P F + L D G+ C + S ++ W K+ + ++
Sbjct: 7106 VLVIKARKLP-------PFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKD 7158
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
+ + + +L+I + G Y C A NPLG AS ++
Sbjct: 7159 DANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 7203
Score = 39.7 bits (91), Expect = 0.004
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L + T+ + PGPP + + S ++W P G + ++GY +++ + S L
Sbjct: 22327 LNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSIL 22386
Query: 192 WFTVLEH-YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
W + + +T + L G Y FRV AEN G+ + + ++
Sbjct: 22387 WVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 22430
Score = 39.7 bits (91), Expect = 0.004
Identities = 55/295 (18%), Positives = 110/295 (37%), Gaps = 32/295 (10%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQLR 126
G V G+P P+ W + + + VS+ L IR A +DSG+Y ++
Sbjct: 33148 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 33207
Query: 127 VQ--LGGLEATATIDIL-VIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLG---- 179
+ G ATA++ +L ++E P ++ +G+T+L G
Sbjct: 33208 AKNFRGQCSATASLMVLPLVEEPSREVVLR-----------------TSGDTSLQGSFSS 33250
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPI-TTDLA 238
+VQ + +K F+ +S ++ + E+ +S ++ + +++
Sbjct: 33251 QSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT 33310
Query: 239 HIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWL--K 296
++ + + G PK +D + G + C P P++ W
Sbjct: 33311 QLESSTSKMLKAGIR----GIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 33366
Query: 297 NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
K+ Q ++ + +L I DGG+YT N G S + ++
Sbjct: 33367 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 33421
Score = 39.3 bits (90), Expect = 0.005
Identities = 63/295 (21%), Positives = 104/295 (35%), Gaps = 35/295 (11%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
+G Q P + W G + ++ + S+R+ + S L I Q D G Y
Sbjct: 3469 LGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTC 3528
Query: 126 RV--QLGGLEATATIDILVIERP---GPPQSIKLV--DVWGFSATLEWTPPQDTGNTALL 178
+ + G + TAT+ + P P+S+ F T+ TP +T +
Sbjct: 3529 KASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIET-----I 3583
Query: 179 GYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
A + S W + + ++ +S+L I + + A N+ G A
Sbjct: 3584 WQKDGAALSPSPNW-RISDAENKHILELSNLTIQDRGVYSCKASNKFG-----------A 3631
Query: 239 HIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNK 298
I +A + K P F + L + L C V + + W K+
Sbjct: 3632 DICQAELIIIDK----------PHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDG 3681
Query: 299 MDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ Y+ I +LEI D G Y C A N G +S V V+ P
Sbjct: 3682 QKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREP 3736
Score = 39.3 bits (90), Expect = 0.005
Identities = 22/72 (30%), Positives = 33/72 (45%)
Query: 282 CCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
C V + KI W K+ +I+ Y+ +L + K G D G YTC A N G+
Sbjct: 7233 CHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGK 7292
Query: 342 ASVDCRVDVKVP 353
S ++ V+ P
Sbjct: 7293 DSCSAQLGVQEP 7304
Score = 39.3 bits (90), Expect = 0.005
Identities = 23/93 (24%), Positives = 37/93 (39%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P F + L G + L C + +P + W K ++ Y+ + +L
Sbjct: 7959 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8018
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
+ D G Y CKA N +GE S + V+
Sbjct: 8019 VFNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051
Score = 39.3 bits (90), Expect = 0.005
Identities = 59/346 (17%), Positives = 123/346 (35%), Gaps = 52/346 (15%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLI 75
K+ E +D + +++ + P+ PI P I L+ T + +
Sbjct: 32820 KISETKKSDQKTTESTVTRKTEPKAPE---PISSKPVI--VTGLQDTTVSS-DSVAKFAV 32873
Query: 76 PFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQ--LGGL 132
G+P+P AIWT DG A+ + + + L I + +DSG Y V+ G +
Sbjct: 32874 KATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSV 32933
Query: 133 EATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
++ + I I + Q + + + ++ AL ++ ++ KS
Sbjct: 32934 SSSCKLTIKAI-KDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKS--- 32989
Query: 193 FTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGF 252
+ + L E A ++K+A K
Sbjct: 32990 -----------------------------QEKLALKEEASKVLISEEVKKSAATSLEKSI 33020
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYNTQ--------LFCCVRASPRPKIIWLKNKMDIQGN 304
+ ++ + ++ + + ++TQ L + + W+ N +++ +
Sbjct: 33021 VHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNS 33080
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+YR +L I++ D GI TC ++ E V C+ D+
Sbjct: 33081 EEYRYGVSGSDQTLTIKQASHRDEGILTC--ISKTKEGIVKCQYDL 33124
Score = 38.9 bits (89), Expect = 0.007
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 163 TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFA 221
T+ W PP D G + + GY ++K +T++ W V + + + L G Y FRV A
Sbjct: 19505 TVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTA 19564
Query: 222 ENQCG 226
N+ G
Sbjct: 19565 INKAG 19569
Score = 38.5 bits (88), Expect = 0.009
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 25/162 (15%)
Query: 2 EAATAPEVAAGSKLKVKEA-----SPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLP 56
EA E AA K +K SP +AE + PG G P +E P +
Sbjct: 11058 EAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPP-------DEAPFTYQL 11110
Query: 57 RALRQTYIRKVGDTVNLLIPFQGKP-------KPQAI---WTHDGCAL--DTRRVSVRNG 104
+A+ +++++ D + F G P W DG + + + +G
Sbjct: 11111 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADG 11170
Query: 105 EQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERP 146
+ D L I + Q +D+G Y ++LG E T+T ++V E P
Sbjct: 11171 K-DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP 11211
Score = 38.1 bits (87), Expect = 0.012
Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 3/115 (2%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWT 88
+A+ G G + T +LL E P ++ R T + G V L + G P P +
Sbjct: 81 KATNGSGQATSTAELLVKAETAPPNFVQRLQSMTV--RQGSQVRLQVRVTGIPTPVVKFY 138
Query: 89 HDGCALDTRRVSVRNGEQDSI-LFIREAQRADSGRYQLRVQLGGLEATATIDILV 142
DG + + + E D L I EA DSG Y + AT+T ++LV
Sbjct: 139 RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 37.0 bits (84), Expect = 0.027
Identities = 23/83 (27%), Positives = 37/83 (44%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P F Q L T G +L V P P + + ++ +IQ + ++ + SL I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 321 RKPGPFDGGIYTCKAVNPLGEAS 343
+ P D G Y+ A N +G A+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRAT 186
Score = 37.0 bits (84), Expect = 0.027
Identities = 56/302 (18%), Positives = 102/302 (33%), Gaps = 35/302 (11%)
Query: 59 LRQTYIRKVGDTVNLLIPFQGKPKPQAIW-THDGCALDTRRVSVRNGEQDSILFIREAQR 117
L + + K GD L G P + W +D ++ + + E ++L + +
Sbjct: 4305 LEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGI 4364
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERP------GPPQSIKLVDVWGFSATLEWTPPQD 171
DSG Y Q + ++V E P P + +K DV A + TPP +
Sbjct: 4365 EDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVM-LLAEVAGTPPFE 4423
Query: 172 TGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
+ + +SG + H S + + ++ ++ N+ G S +
Sbjct: 4424 ------ITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICS 4477
Query: 232 PITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPK 291
T E P F + + +++ G ++ S
Sbjct: 4478 ARVT---------------------LREPPSFIKKIESTSSLRGGTAAFQATLKGSLPIT 4516
Query: 292 IIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
+ WLK+ +I + R + SL + G Y C+A N G + VK
Sbjct: 4517 VTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK 4576
Query: 352 VP 353
P
Sbjct: 4577 EP 4578
Score = 37.0 bits (84), Expect = 0.027
Identities = 69/305 (22%), Positives = 109/305 (35%), Gaps = 44/305 (14%)
Query: 57 RALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-------TRRVSVRNGEQDSI 109
R L+ + K D V L G P + W + + T RVSV N
Sbjct: 4959 RELKPVEVVKYSD-VELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFN------ 5011
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVD----VWGFSATLE 165
L I + +D+G YQ V G + + + + E PP IK ++ V SAT +
Sbjct: 5012 LHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKE---PPSFIKKIENTTTVLKSSATFQ 5068
Query: 166 WTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQC 225
T + Q D ++ + ++ + + + G+S + A+N+
Sbjct: 5069 STVAGSPPISITWLKDDQILDEDDNVYISFVDSV--ATLQIRSVDNGHSGRYTCQAKNES 5126
Query: 226 GLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVR 285
G+ L + A V K K D +E T L C V
Sbjct: 5127 GVERCYAF---LLVQEPAQIVEKAKSV---DVTEKDPMT---------------LECVVA 5165
Query: 286 ASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVD 345
+P K+ WLK+ I + + + S I+ D G YT K N G +S D
Sbjct: 5166 GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCD 5225
Query: 346 CRVDV 350
+ V
Sbjct: 5226 AYLRV 5230
Score = 36.6 bits (83), Expect = 0.035
Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 22/126 (17%)
Query: 13 SKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKV----- 67
+++ SPA P + SPG+ +EE + L R + ++ K
Sbjct: 1420 ARMSPARMSPARMSPARMSPGRR-----------LEETDESQLERLYKPVFVLKPVSFKC 1468
Query: 68 --GDTVNLLIPFQGKPKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIREAQRADSGR 122
G T + G+P P+ W HDG + T +V ++ S++ + A +DSG
Sbjct: 1469 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGE 1527
Query: 123 YQLRVQ 128
+ + Q
Sbjct: 1528 WTVVAQ 1533
Score = 36.6 bits (83), Expect = 0.035
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P PL D T G + C V + K+ W I+ + +R LEI
Sbjct: 3345 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3403
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ P D G YT A N +G+ S + ++ P
Sbjct: 3404 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436
Score = 36.6 bits (83), Expect = 0.035
Identities = 24/96 (25%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 259 EAPKFTQ-PLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
E P+F + P G +T C + +P+ ++ W + +I K+ G+ +
Sbjct: 4859 EPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLAT 4918
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+I + G Y C+A N G AS + VK P
Sbjct: 4919 FQISGARVENSGTYVCEARNDAGTASCSIELKVKEP 4954
Score = 36.2 bits (82), Expect = 0.046
Identities = 23/80 (28%), Positives = 35/80 (43%)
Query: 271 TTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330
T G L C V +P + W K+ + + K++ + I SL I D G
Sbjct: 5714 TVTVGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGT 5773
Query: 331 YTCKAVNPLGEASVDCRVDV 350
YT + N +G++S VDV
Sbjct: 5774 YTFQVQNNVGKSSCTAVVDV 5793
Score = 35.4 bits (80), Expect = 0.078
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 258 SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN--PKYRALTHLGI 315
++AP FTQPL + G + P P++ W ++ I + P + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L I + G Y+ KA N G+A+ + VK
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 35.4 bits (80), Expect = 0.078
Identities = 61/291 (20%), Positives = 100/291 (34%), Gaps = 28/291 (9%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLR 126
GD L + F G + A W DG L + + + SIL I ++ DSG Y
Sbjct: 4593 GDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFE 4652
Query: 127 VQ--LGGLEATATIDIL-VIERPGPPQSIKLVD-VWGFSATLEWTPPQDTGNTALLGYTV 182
VQ +G A I++L +I P + +K +D + G LE + + +
Sbjct: 4653 VQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVA--GSHPISIQWFK 4710
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQK 242
+ + + H + +S L +S + A N+ G ++ + T
Sbjct: 4711 DDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLT------- 4763
Query: 243 AATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ 302
E P F + QL V + I W K+ ++
Sbjct: 4764 --------------VKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELH 4809
Query: 303 GNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
SLE+ D G Y C+ N +G A+ + VK P
Sbjct: 4810 SGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEP 4860
Score = 35.0 bits (79), Expect = 0.10
Identities = 59/286 (20%), Positives = 104/286 (36%), Gaps = 24/286 (8%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLR 126
G V L G P + +W D + ++++ + + D+ L I + +D G Y +
Sbjct: 6472 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 6531
Query: 127 VQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKAD 186
T + + E PP+ +K + ++TL G+ L V+
Sbjct: 6532 ATNEVGSDTCSCSVKFKE---PPRFVKKLSD---TSTL-------IGDAVELRAIVEGFQ 6578
Query: 187 TKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATV 246
S +W R S I N A Q G E + + I+ A +
Sbjct: 6579 PISVVWLKDRGEVIRESENTRISFIDN------IATLQLGSPEASNSGKYICQIKNDAGM 6632
Query: 247 YKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPK 306
+ A E + + T TG L C V +P W K+ ++ + K
Sbjct: 6633 RECS--AVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSK 6690
Query: 307 YRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
+ + SL+I D G+Y+ + N +G++ +C V V V
Sbjct: 6691 HHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKS--NCTVSVHV 6734
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA-LTHLGICSLEIR 321
F + + + G C + P PKI W K+ I+ +Y+ G SL I
Sbjct: 1293 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1352
Query: 322 KPGPFDGGIYTCKAVNPLGEA 342
P D GIYT A N G A
Sbjct: 1353 VVLPEDEGIYTAFASNIKGNA 1373
Score = 34.7 bits (78), Expect = 0.13
Identities = 18/64 (28%), Positives = 27/64 (42%)
Query: 288 PRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCR 347
P + WL + ++ + R + G CSL+ D GI TC+A N G
Sbjct: 1732 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1791
Query: 348 VDVK 351
+ VK
Sbjct: 1792 LIVK 1795
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPK-YRALTHLGICS 317
EAPK + + T G + V P P+ W KN + I+ + + Y +C
Sbjct: 2076 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2135
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEAS 343
L IR D KA+N GE S
Sbjct: 2136 LVIRDVTAEDSASIMVKAINIAGETS 2161
Score = 33.9 bits (76), Expect = 0.23
Identities = 64/278 (23%), Positives = 101/278 (36%), Gaps = 41/278 (14%)
Query: 69 DTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRV 127
DT+ L+ KP + IW D ++T R + + IL I+ A D+G Y R+
Sbjct: 12478 DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRL 12536
Query: 128 QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ-KAD 186
+ + L E PQ++++ LE + + + + VQ K D
Sbjct: 12537 PSSRTDGKVKVHELAAEFISKPQNLEI---------LEGEKAEFVCSISKESFPVQWKRD 12587
Query: 187 TK---SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
K SG + V+ + +V D + + + V G + A AH+
Sbjct: 12588 DKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAA------AHL--- 12634
Query: 244 ATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
TV E + PL D T V +F C + K W +N+ I
Sbjct: 12635 -TVI-----------EKLRIVVPLKD-TRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFD 12681
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
+ KY L + +L IR D Y N GE
Sbjct: 12682 SSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGE 12719
Score = 33.5 bits (75), Expect = 0.30
Identities = 17/61 (27%), Positives = 26/61 (42%)
Query: 291 KIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
++ W ++ + KY G+ L ++ D G Y CK VN GE S + V
Sbjct: 31599 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 31658
Query: 351 K 351
K
Sbjct: 31659 K 31659
Score = 33.1 bits (74), Expect = 0.39
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 260 APKF-TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL--THLGIC 316
AP F T+P+ V G + C V +P+P + W K+ + + +Y+ G C
Sbjct: 1081 APYFITKPVVQ-KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGEC 1139
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEAS 343
L I D G YT N GE S
Sbjct: 1140 KLVISMTFADDAGEYTIVVRNKHGETS 1166
Score = 32.7 bits (73), Expect = 0.51
Identities = 21/74 (28%), Positives = 29/74 (39%)
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
FTQ L D F C + P K+ W K+ M++ KYR + + L I
Sbjct: 2176 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILT 2235
Query: 323 PGPFDGGIYTCKAV 336
D Y+C V
Sbjct: 2236 IDTSDAEDYSCVLV 2249
Score = 31.6 bits (70), Expect = 1.1
Identities = 25/70 (35%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 284 VRASPRPKIIWLKNKMDIQGNPKYRALTHL--GICSLEIRKPGPFDGGIYTCKAVNPLG- 340
V P P + W K K Q N R H LEIR D G+Y C A N G
Sbjct: 8477 VGGDPIPNVKWTKGKWR-QLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGE 8535
Query: 341 -EASVDCRVD 349
E++V+ +VD
Sbjct: 8536 IESNVNLQVD 8545
Score = 31.2 bits (69), Expect = 1.5
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 245 TVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
T + K A+ EAP +F + L D TVT ++ +F C + + + W +N +I+
Sbjct: 12806 TAGQDKSVAELLIIEAPTEFVEHLED-QTVTEFDDAVFSCQLSREKANVKWYRNGREIKE 12864
Query: 304 NPKYR 308
KY+
Sbjct: 12865 GKKYK 12869
Score = 30.4 bits (67), Expect = 2.5
Identities = 59/294 (20%), Positives = 101/294 (34%), Gaps = 37/294 (12%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLR 126
G +V + G P W H+G + + R+ + L + + +DSG Y
Sbjct: 7696 GSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCI 7755
Query: 127 V--QLGGLEATATIDIL----VIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY 180
G E +A + + +++P P + +V F++ ++ TPP
Sbjct: 7756 ATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVT-FTSIVKGTPPFSVSWFKGSSE 7814
Query: 181 TVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHI 240
V L +V E + D+ S + N+ G A TT L
Sbjct: 7815 LVPGDRCNVSLEDSVAE------LELFDVDTSQSGEYTCIVSNEAG---KASCTTHL--- 7862
Query: 241 QKAATVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKM 299
+ +AP KF + L D + G L +P + W KN +
Sbjct: 7863 ----------------YIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGI 7906
Query: 300 DIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
++ + + T LEI D G Y C N G+ S ++ + P
Sbjct: 7907 NVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEP 7960
Score = 30.0 bits (66), Expect = 3.3
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 275 GYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCK 334
G + C V P+PK+ W N I+ + ++R + + GI L+I +D G
Sbjct: 1855 GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFR-VRYDGIHYLDIVDCKSYDTGEVKVT 1913
Query: 335 AVNPLGEASVDCRVDVK 351
A NP G +++++
Sbjct: 1914 AENPEGVIEHKVKLEIQ 1930
Score = 29.6 bits (65), Expect = 4.3
Identities = 21/82 (25%), Positives = 33/82 (40%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E F + L+D + G + L + + W K+ +I + K +T C L
Sbjct: 5984 EPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCIL 6043
Query: 319 EIRKPGPFDGGIYTCKAVNPLG 340
EI D G Y+C+ N G
Sbjct: 6044 EILNSTKRDAGQYSCEIENEAG 6065
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPK-IIWLKNKMDIQGNPKYRALTHLGICS 317
EA K + L + T VT +F P K + W+KN + ++ N KY I S
Sbjct: 2705 EAVKIKKTLKNLT-VTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYS 2763
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L I+ D +Y + LG R+ V+
Sbjct: 2764 LRIKNCAIVDESVYGFR----LGRLGASARLHVE 2793
Score = 28.9 bits (63), Expect = 7.3
Identities = 28/96 (29%), Positives = 33/96 (34%), Gaps = 2/96 (2%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHLGICS 317
E P F + G L + S I W K NK + G Y L S
Sbjct: 4204 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALE-SS 4262
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
LE+ D G YTCK N G + VK P
Sbjct: 4263 LELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEP 4298
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 113 bits (283), Expect = 2e-25
Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 5/177 (2%)
Query: 62 TYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADS 120
+Y +VG + + +P G+PKP WT DG L T R++V + + L I+E + D
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 16992
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLG 179
G+Y + V + TA+I+I+ +++P PP+ +K DV S TL W PP TG +
Sbjct: 16993 GQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITN 17052
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETAPI 233
Y VQK DT + +W V RT+ V+ L G Y FR+FAEN+ G S E+ PI
Sbjct: 17053 YIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI 17109
Score = 112 bits (280), Expect = 5e-25
Identities = 67/189 (35%), Positives = 100/189 (52%), Gaps = 4/189 (2%)
Query: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRV 99
P + IE P + LP T+ K + + + +PF+G+P+ W DG L +T RV
Sbjct: 19080 PVIARDIEIKPSVELPF---HTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRV 19136
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWG 159
+V + + + L I+EA + D G Y+L V T I I+V++RPGPP I++ +V
Sbjct: 19137 NVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSC 19196
Query: 160 FSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRV 219
S T+ W PP+ G + Y V+K +T S W V + RTS + L G+ Y FRV
Sbjct: 19197 DSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRV 19256
Query: 220 FAENQCGLS 228
AEN+ G S
Sbjct: 19257 CAENRYGKS 19265
Score = 110 bits (275), Expect = 2e-24
Identities = 67/212 (31%), Positives = 105/212 (49%), Gaps = 8/212 (3%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLI 75
+VK + A P + S PQ+ EE P + +R+T I K G + + +
Sbjct: 19851 RVKSVNKVGASDP-------SDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTV 19903
Query: 76 PFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEAT 135
PF+G+P P +W+ L TR V + + L I A R DSG+Y L +Q A+
Sbjct: 19904 PFRGRPVPNVLWSKPDTDLRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAAS 19962
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
T+ + V++ PGPP +I + DV SA L W P++ G + Y ++K + W +V
Sbjct: 19963 LTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSV 20022
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
+ +R S V++L G Y FRV EN+ G+
Sbjct: 20023 TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 20054
Score = 108 bits (270), Expect = 7e-24
Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 6/185 (3%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD-GCALDTRRVSVRNGEQDSI 109
P+I L LR+ + T+ L +P +G+P P+ W D G +LD + S+ + ++
Sbjct: 15553 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIESTSSYTL 15610
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPP 169
L + R DSG+Y L V+ +A +++ V++ PGPPQ +K+ +V S TL W PP
Sbjct: 15611 LIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPP 15670
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL-- 227
G + + Y V+K ++ + TV + H+TS V L G SY FRV AEN+ G+
Sbjct: 15671 LLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGL 15730
Query: 228 -SETA 231
+ETA
Sbjct: 15731 PAETA 15735
Score = 108 bits (270), Expect = 7e-24
Identities = 68/206 (33%), Positives = 102/206 (49%), Gaps = 6/206 (2%)
Query: 35 GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G G P P I E P+I L ALR + I K G+ V +LIPF+G+P P W D
Sbjct: 20944 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKD 21003
Query: 91 GCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG-GLEATATIDILVIERPGP 148
L + R S+ N + S+L I + R D+G+Y L ++ G G ++T+ + V++ P
Sbjct: 21004 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAA 21063
Query: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
Q +++ V + TL W PP G + ++ Y ++K D W V TS + D
Sbjct: 21064 CQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLID 21123
Query: 209 LIIGNSYAFRVFAENQCGLSETAPIT 234
L + FRV AEN+ G+ E T
Sbjct: 21124 LSEKTPFFFRVLAENEIGIGEPCETT 21149
Score = 107 bits (266), Expect = 2e-23
Identities = 75/252 (29%), Positives = 122/252 (48%), Gaps = 14/252 (5%)
Query: 57 RALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREA 115
+ L T+ G+ + + +PF G+P P W D L T RV+ + E +S+L I++A
Sbjct: 15846 KLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDA 15905
Query: 116 QRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGN 174
R D G Y +++ EA T++++V+++PGPP +K+ +V S TL W PP+ G
Sbjct: 15906 CREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGG 15965
Query: 175 TALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETA 231
+++ Y V+K DT + W V RT+ L G Y FR+ AEN+ G S +
Sbjct: 15966 SSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE 16025
Query: 232 PITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLAD-CTTVTGYNTQLFCCVRASPRP 290
P + RD E ++ +P++D + V GY+ + R
Sbjct: 16026 PTVAQYPFKVPGPPGTPVVTLSSRDSMEV-QWNEPISDGGSRVIGYH------LERKERN 16078
Query: 291 KIIWLK-NKMDI 301
I+W+K NK I
Sbjct: 16079 SILWVKLNKTPI 16090
Score = 106 bits (265), Expect = 3e-23
Identities = 62/192 (32%), Positives = 102/192 (53%), Gaps = 6/192 (3%)
Query: 39 PTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR- 97
P L+PP E L LR+T I + G T+ L +P +G+P P+ W+ L R
Sbjct: 13379 PKDILIPPEGE-----LDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRI 13433
Query: 98 RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDV 157
+ +++ + D+ L + D+G+Y L ++ + TI + V++ PGPP ++ + ++
Sbjct: 13434 GLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEI 13493
Query: 158 WGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAF 217
SA + W PP G + ++ Y VQK D + W TV +TS V++L G SY F
Sbjct: 13494 SKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFF 13553
Query: 218 RVFAENQCGLSE 229
RVFAEN+ G+ +
Sbjct: 13554 RVFAENEYGIGD 13565
Score = 105 bits (263), Expect = 5e-23
Identities = 62/203 (30%), Positives = 100/203 (49%), Gaps = 7/203 (3%)
Query: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRV 99
P + + P + LP TY + G+ + + IP G+P+P W DG L T RV
Sbjct: 17997 PVIAKDLTIQPSLKLPF---NTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRV 18053
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVW 158
+V ++L I+E + D G+Y + AT + ++V+E+PGPP ++ +V
Sbjct: 18054 NVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVS 18113
Query: 159 GFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFR 218
+ W PP TG + Y V+K DT + W V RT+ ++ L G Y FR
Sbjct: 18114 ADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFR 18173
Query: 219 VFAENQCGLSETAPITTDLAHIQ 241
+FAEN+ G ++AP+ + +Q
Sbjct: 18174 IFAENRYG--KSAPLDSKAVIVQ 18194
Score = 104 bits (259), Expect = 1e-22
Identities = 71/226 (31%), Positives = 104/226 (46%), Gaps = 13/226 (5%)
Query: 12 GSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTV 71
G K K + A+ +G QLLPP KI +P + K G +
Sbjct: 12561 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPP-----KILMPEQITI----KAGKKL 12611
Query: 72 NLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG 130
+ GKP P W + + + ++V + SIL I++ R DSG Y L +
Sbjct: 12612 RIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 12671
Query: 131 GLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKS 189
T I ++V++ PGPPQ + D+ + +L W P + G + + Y V+K D
Sbjct: 12672 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSR 12731
Query: 190 GLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITT 235
G W T L +TSC V LI G Y FRV AEN+ G+SE P+T+
Sbjct: 12732 GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE--PLTS 12775
Score = 103 bits (257), Expect = 2e-22
Identities = 60/191 (31%), Positives = 97/191 (50%), Gaps = 4/191 (2%)
Query: 48 EEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQ 106
+E P+I+L L K G + L GKP+P+ WT L +R+++ N +
Sbjct: 7380 QEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK 7439
Query: 107 DSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEW 166
S + I +++R+D+G Y + ATA +++ V+++PGPP + + DV S L W
Sbjct: 7440 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7499
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
PP+D G + + Y V++ T S +W + T+ + LI Y FRV AEN G
Sbjct: 7500 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 7559
Query: 227 LSE---TAPIT 234
+ E +PIT
Sbjct: 7560 VGEPVQASPIT 7570
Score = 102 bits (255), Expect = 4e-22
Identities = 57/204 (27%), Positives = 101/204 (49%), Gaps = 6/204 (2%)
Query: 36 AGSPTPQLLPPIE-----EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
AG P ++P +E P L LR+T + + G ++ + +P +G+P P+ WT D
Sbjct: 14449 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14508
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
L R ++ N E ++L I E R D+G++ + ++ + + +++ V++ PGP
Sbjct: 14509 NINLKNR-ANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14567
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
+++ D+ S TL W P G + + Y V+K + + T H+ + V+ L
Sbjct: 14568 NLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLS 14627
Query: 211 IGNSYAFRVFAENQCGLSETAPIT 234
G Y FRV AEN+ G+ E T
Sbjct: 14628 EGCEYFFRVMAENEYGIGEPTETT 14651
Score = 102 bits (253), Expect = 7e-22
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 2/190 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDT-RRVSVRNGEQDSI 109
P + L L + + K G TV +G P P A WT DG + T +V S+
Sbjct: 11203 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11262
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L I+ R D+G YQ+ V T + + V++ PGPP I ++DV T+ W P
Sbjct: 11263 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP 11322
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P+D G + ++ Y V+K DT+ W V +T + L G Y FRV AEN+ G+
Sbjct: 11323 PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVG 11382
Query: 229 ETAPITTDLA 238
T +A
Sbjct: 11383 PPLDSTPTVA 11392
Score = 101 bits (252), Expect = 9e-22
Identities = 61/176 (34%), Positives = 93/176 (52%), Gaps = 10/176 (5%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCALD---TRRVSVRNGEQDSILFIREAQRADSGR 122
K GDT+ L +GKP P+ WT D A D + RV + S + +A+R+D G+
Sbjct: 11909 KAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGK 11968
Query: 123 YQLRVQ--LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY 180
Y + G A AT+++L ++PGP +++K+VDV T+ W PP+D G + Y
Sbjct: 11969 YVVTATNTAGSFVAYATVNVL--DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNY 12026
Query: 181 TVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL---SETAPI 233
++K +TK +W T V+ LI GN Y FRV AEN+ G +E+ P+
Sbjct: 12027 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPV 12082
Score = 101 bits (252), Expect = 9e-22
Identities = 61/199 (30%), Positives = 96/199 (48%), Gaps = 2/199 (1%)
Query: 32 PGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDG 91
PG+ A P + + E+P L ++ + G + L IP +GKP P WT +G
Sbjct: 23810 PGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG 23869
Query: 92 CALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS 151
+ ++R + E + L I+EA R DSG Y L ++ + I + VI P P+
Sbjct: 23870 QDI-SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEG 23928
Query: 152 -IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
++ D+ S + W PP D G +LGY +++ + W+T+ TS +V L
Sbjct: 23929 PLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLK 23988
Query: 211 IGNSYAFRVFAENQCGLSE 229
Y FRV AENQ G+S+
Sbjct: 23989 ENVEYHFRVSAENQFGISK 24007
Score = 101 bits (251), Expect = 1e-21
Identities = 86/307 (28%), Positives = 134/307 (43%), Gaps = 30/307 (9%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRR-VSVRNGEQDSI 109
P I LP + + G +V L GKP P W D L T V V N +
Sbjct: 20565 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20624
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
+ I++A R +SG Y+L+++ A+ATI + ++++PGPP I+ V TL W P
Sbjct: 20625 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRP 20684
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P D G + Y V+K +T +W V EH + +I GN Y FRV A N+ G+
Sbjct: 20685 PADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIG 20744
Query: 229 ETAPITTDLAHIQKAATVYKTKGFAQ----RDFSEAPKFTQPLAD-CTTVTGY------- 276
E P+ +D + A G + S +++P+AD + ++GY
Sbjct: 20745 E--PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDK 20802
Query: 277 -NTQLFCCVRAS---PRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYT 332
+ F ++ + R K+ L D Q YR +C++ GPF
Sbjct: 20803 KSLGWFKVLKETIRDTRQKVTGLTENSDYQ----YR------VCAVNAAGQGPFSEPSEF 20852
Query: 333 CKAVNPL 339
KA +P+
Sbjct: 20853 YKAADPI 20859
Score = 100 bits (248), Expect = 3e-21
Identities = 58/170 (34%), Positives = 89/170 (52%), Gaps = 4/170 (2%)
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWT--HDGCALDTRRVSVRNGEQDSILFIREAQRADS 120
Y+ K L IP +GKP P W D A DTR VSV + ++ L + + Q++D+
Sbjct: 13687 YLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTR-VSVESSAVNTTLIVYDCQKSDA 13745
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLG 179
G+Y + ++ TI I V+ +PG P IK +V + TL+W PP+D G + +
Sbjct: 13746 GKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITN 13805
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
Y ++K D+ + W T +T+ V+ L G Y FRV AEN+ G+ E
Sbjct: 13806 YILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13855
Score = 99.8 bits (247), Expect = 3e-21
Identities = 55/166 (33%), Positives = 83/166 (50%), Gaps = 1/166 (0%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQL 125
V + + +L+P G P+P A W L+T RV ++ + L I ++R+D G Y L
Sbjct: 7103 VPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTL 7162
Query: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
+++ + ID+ VI RP P+ +K D+ S L W PP D G + L GY V+K
Sbjct: 7163 KLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR 7222
Query: 186 DTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
+ W V++ V DL+ G Y F+V A N+CG E A
Sbjct: 7223 EVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268
Score = 99.8 bits (247), Expect = 3e-21
Identities = 62/201 (30%), Positives = 99/201 (49%), Gaps = 6/201 (2%)
Query: 35 GAGSPTPQLLPPIE----EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G P LLP + E P+I + T + G + + IP GKP P+ + D
Sbjct: 20149 GLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRD 20208
Query: 91 GCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
G L T R + ++ + ++E+ AD+GRY++ A I+I+V++RPGPP
Sbjct: 20209 GVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPP 20268
Query: 150 QS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
+ + D+ S TL+W PP+ G + + Y + K +T + +W V RT V
Sbjct: 20269 TGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMK 20328
Query: 209 LIIGNSYAFRVFAENQCGLSE 229
L G Y FR+ AEN+ G+S+
Sbjct: 20329 LTTGEEYQFRIKAENRFGISD 20349
Score = 99.4 bits (246), Expect = 4e-21
Identities = 61/234 (26%), Positives = 106/234 (45%), Gaps = 19/234 (8%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNL 73
+ +VK + A P + G+ + I+E P++++ + + K G + +
Sbjct: 9473 RFRVKAVNEAGESEPSDTTGEIPATD-------IQEEPEVFIDIGAQDCLVCKAGSQIRI 9525
Query: 74 LIPFQGKPKPQAIWTHDGCALDTRRVSVRN---------GEQDSILFIREAQRADSGRYQ 124
+G+P P++ W DG A + V + E S++ I E +R+ +G+Y
Sbjct: 9526 PAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYS 9585
Query: 125 LRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK 184
+ + + TA + V++ PGPP+ +K+ D+ S L W P D G + GY ++K
Sbjct: 9586 ITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEK 9645
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETAPITT 235
W V T+ +V DL+ Y FRV AEN+ G+ ET TT
Sbjct: 9646 RTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTT 9699
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/190 (32%), Positives = 92/190 (48%), Gaps = 5/190 (2%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSI- 109
P+I L A++ K G V L GKP P W DG L ++ Q ++
Sbjct: 12988 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE-GIKMAMQRNLC 13046
Query: 110 -LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTP 168
L + R DSG Y + + +ATI + V+++PGPP S+K+ ++ A L W P
Sbjct: 13047 TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEP 13106
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P + G + + Y V K +T W V TSC V LI G+ Y FR+ AEN+ G+
Sbjct: 13107 PLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVG 13166
Query: 229 ETAPITTDLA 238
+ P+ T+ A
Sbjct: 13167 D--PVFTEPA 13174
Score = 98.6 bits (244), Expect = 8e-21
Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQD 107
E PKI + + T I K G+ L G+P P W+ DG L+ T ++ ++ +
Sbjct: 15152 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS 15211
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEW 166
+ L +++ R DSG Y L G A ++ V++RPGPP+ + + +V L W
Sbjct: 15212 TNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSW 15271
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
PP D G + Y VQK +T W V T V+ L+ GN Y FRV A N+ G
Sbjct: 15272 FPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYG 15331
Query: 227 LSE 229
+ E
Sbjct: 15332 VGE 15334
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/225 (27%), Positives = 108/225 (48%), Gaps = 12/225 (5%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P+I + + T + G++ + GKP P W L +T R+ +++ + +
Sbjct: 16236 PRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS 16295
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L +++A R DSG Y L+ + E + T+++ V++RPGPP+ + + V TL W P
Sbjct: 16296 LSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKP 16355
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P G + ++ Y V++ +T +W V + SC V+ L+ GN Y FR+ A N+ G+
Sbjct: 16356 PLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 16415
Query: 229 ETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTV 273
E P+ ++ V F D +AP+ T D V
Sbjct: 16416 E--PLESE--------PVVAKNPFVVPDAPKAPEVTTVTKDSMIV 16450
Score = 98.2 bits (243), Expect = 1e-20
Identities = 60/200 (30%), Positives = 97/200 (48%), Gaps = 2/200 (1%)
Query: 29 QASPGQGAGSPTPQLLPPIE--EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAI 86
Q G G + + + P E E P+I L ++R+ I + G + L +G+P P+
Sbjct: 12275 QNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVT 12334
Query: 87 WTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERP 146
W G R+ V + + L I + R DSG+Y L + E +++ V++ P
Sbjct: 12335 WRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTP 12394
Query: 147 GPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIV 206
GP +K+ DV S + W PP++ G + + Y V+K + W TV +TS V
Sbjct: 12395 GPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHV 12454
Query: 207 SDLIIGNSYAFRVFAENQCG 226
++L+ GN Y FRV A N+ G
Sbjct: 12455 TNLVPGNEYYFRVTAVNEYG 12474
Score = 97.8 bits (242), Expect = 1e-20
Identities = 60/205 (29%), Positives = 102/205 (49%), Gaps = 5/205 (2%)
Query: 33 GQGAGSPTPQLLPPIE--EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G G + P + P + E P++ L LR+ + + G + + IPF+G+P P+ W+ +
Sbjct: 17697 GLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSRE 17756
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
T +V + G + L I R D+G+Y L+++ +A + + V++ PGPPQ
Sbjct: 17757 EGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQ 17815
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
++ + +V SA L W PP G + Y + K ++ + V +TS V +L
Sbjct: 17816 NLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLT 17875
Query: 211 IGNSYAFRVFAENQCGLSETAPITT 235
G Y FRV AEN+ G+ P+ T
Sbjct: 17876 EGAIYYFRVMAENEFGVG--VPVET 17898
Score = 97.8 bits (242), Expect = 1e-20
Identities = 56/179 (31%), Positives = 86/179 (48%), Gaps = 1/179 (0%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
P++ + +QT++ + G ++ L I +QG+P P A+W+ L R + + S L
Sbjct: 22050 PELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR-ADIHTTDSFSTL 22108
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQ 170
+ R D+G+Y L V+ + T + V++ PGPP I DV SATL W P
Sbjct: 22109 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPL 22168
Query: 171 DTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
G + Y V+K + W + E R V+DL G Y FRV A N+ G+ E
Sbjct: 22169 LDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGE 22227
Score = 97.4 bits (241), Expect = 2e-20
Identities = 60/179 (33%), Positives = 91/179 (50%), Gaps = 2/179 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P I L ++T G V L+IP G+P P A W G L ++ RV+V + +
Sbjct: 23431 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23490
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L IRE D+G Y L ++ + TI ++++++PGPP IK+ ++ S T+ W P
Sbjct: 23491 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23550
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
P+ G L GY V++ D W V E R++ + L GN Y FRV A N+ G+
Sbjct: 23551 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGI 23609
Score = 96.7 bits (239), Expect = 3e-20
Identities = 55/190 (28%), Positives = 94/190 (49%), Gaps = 5/190 (2%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQD 107
E P+I + R T + G+T L GKP P W ++ + R ++N +
Sbjct: 17316 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17375
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEW 166
++L +++A R D G+Y LR + +++ V++RPGPP+ +++ V +L W
Sbjct: 17376 ALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW 17435
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
+PP G + + Y V+K +T W V S V+ L+ GN Y FR+ A N+ G
Sbjct: 17436 SPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYG 17495
Query: 227 LS---ETAPI 233
+ E+AP+
Sbjct: 17496 VGEPLESAPV 17505
Score = 94.7 bits (234), Expect = 1e-19
Identities = 62/198 (31%), Positives = 92/198 (46%), Gaps = 3/198 (1%)
Query: 30 ASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH 89
A A P P L+ E P++ L + + KVGDT+ L +G P P+ W
Sbjct: 10890 AGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKK 10949
Query: 90 DGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGP 148
+ T+ R+ V S L IR A D G Y L V+ T ++ +LV+++PGP
Sbjct: 10950 EDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGP 11007
Query: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
P+ +++ ++ S L W P D G + + Y V++ D S W + + S
Sbjct: 11008 PRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH 11067
Query: 209 LIIGNSYAFRVFAENQCG 226
L GN Y FRV AENQ G
Sbjct: 11068 LNEGNQYLFRVAAENQYG 11085
Score = 93.6 bits (231), Expect = 2e-19
Identities = 55/190 (28%), Positives = 91/190 (47%), Gaps = 6/190 (3%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD--TRRVSVRNGEQDS 108
P L + + G+T L +GKP P +W+ DG L+ R+ +++ Q +
Sbjct: 18400 PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKT 18459
Query: 109 ILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWT 167
L +++ R D G+Y L++ G + I + V++RPGPP+ +K+ V L W
Sbjct: 18460 TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 18519
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
PP G + Y ++K +T W V + V+ L+ GN Y FRV A N+ G+
Sbjct: 18520 PPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18579
Query: 228 S---ETAPIT 234
E+ P+T
Sbjct: 18580 GEPLESGPVT 18589
Score = 93.6 bits (231), Expect = 2e-19
Identities = 55/187 (29%), Positives = 94/187 (50%), Gaps = 3/187 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQD 107
E P+I L LR+ + + T+ L + +G+P+P+ W +G D ++ V +
Sbjct: 18798 EPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSF-- 18855
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWT 167
++L I R DSGRY L ++ TA +++ V++ P P ++ + +V S TL W
Sbjct: 18856 TMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWE 18915
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
PP G + Y V+K +T + T+ + +T+ + +L G SY FRV A N+ G+
Sbjct: 18916 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975
Query: 228 SETAPIT 234
A T
Sbjct: 18976 GLPAETT 18982
Score = 93.6 bits (231), Expect = 2e-19
Identities = 64/205 (31%), Positives = 100/205 (48%), Gaps = 7/205 (3%)
Query: 45 PPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRN 103
P IE P L Q K G + +P G+P P+ W + L +T RVS+
Sbjct: 22336 PQIE--PTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT 22393
Query: 104 GEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSA 162
+ + L ++++ R DSGRY L ++ T ++ ++VI RPGP I++ V S
Sbjct: 22394 TKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESC 22453
Query: 163 TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAE 222
L W P+D G T + Y V+K ++ + W V RT V+ L Y+FRV +E
Sbjct: 22454 VLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSE 22513
Query: 223 NQCGLS---ETAPITTDLAHIQKAA 244
N+ G+S E+API + + +A
Sbjct: 22514 NRFGVSKPLESAPIIAEHPFVPPSA 22538
Score = 93.2 bits (230), Expect = 3e-19
Identities = 66/236 (27%), Positives = 103/236 (43%), Gaps = 11/236 (4%)
Query: 5 TAPEVAAGS--KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQT 62
T E+ G+ KL+V + A PP G P + +E P + L +++
Sbjct: 8757 TVKEIREGADYKLRVSAVNAAGEGPP--------GETQPVTVAEPQEPPAVELDVSVKGG 8808
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
G T+ + G+P P +WT + LD RV + N S L I++A R D GR
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGR 8868
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Y + A + V + PGP +K V L W+ P+D G + + G+ +
Sbjct: 8869 YVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 8928
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
++ D K W +E R+ C ++ L+ G Y FRV A+N+ G I LA
Sbjct: 8929 ERKDAKMHTWRQPIE-TERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILA 8983
Score = 93.2 bits (230), Expect = 3e-19
Identities = 57/200 (28%), Positives = 98/200 (49%), Gaps = 3/200 (1%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWT 88
+A G+ A P P ++ E P I L LR+ + G ++ L +P +G+P P+ W
Sbjct: 16613 KAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWG 16672
Query: 89 H-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPG 147
DG D + V + +L R DSG+Y L ++ +A + + V++ P
Sbjct: 16673 KVDGEIRDAAIIDVTSSFTSLVL--DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPS 16730
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVS 207
PP ++K+ ++ S ++ W PP G + + Y V+K + + V+ + H+ S +
Sbjct: 16731 PPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKID 16790
Query: 208 DLIIGNSYAFRVFAENQCGL 227
L G SY FRV AEN+ G+
Sbjct: 16791 QLQEGCSYYFRVTAENEYGI 16810
Score = 91.7 bits (226), Expect = 9e-19
Identities = 57/183 (31%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNL-LIPFQGKPKPQAIWTHDGCALDTRRVS-VRNGEQ 106
E P I L ++ K GDT+ L I GKP P++ W+ G + ++ + +
Sbjct: 14069 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14128
Query: 107 DSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEW 166
S+L I+ A R D+G Y + + + V++ PGPP +++ +V ATL W
Sbjct: 14129 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTW 14188
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
TPP + G + + Y ++K +T LW V E + + LI GN Y FRV A N G
Sbjct: 14189 TPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 14248
Query: 227 LSE 229
E
Sbjct: 14249 KGE 14251
Score = 90.5 bits (223), Expect = 2e-18
Identities = 69/223 (30%), Positives = 96/223 (43%), Gaps = 7/223 (3%)
Query: 12 GSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRA-LRQTY----IRK 66
G + V+ + + Q AG P+ P+ + LP LR Y I K
Sbjct: 14714 GLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAK 14773
Query: 67 VGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
GD + + IP G+PKP W D T+RV+ +IL I E R+DSG Y L
Sbjct: 14774 AGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 14833
Query: 126 RVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK 184
+ E I I V + PGPP IK +V T W PP++ G + Y V+
Sbjct: 14834 TARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEM 14893
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
T S W + RT+ + L G Y FRV A+N+ G+
Sbjct: 14894 RQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGV 14936
Score = 90.1 bits (222), Expect = 3e-18
Identities = 56/191 (29%), Positives = 92/191 (48%), Gaps = 2/191 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P++ L R +VG T+ +L +G+P+P WT +G L +RV +
Sbjct: 11601 PEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE 11660
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPP 169
L I+EA RAD G+Y + + A + + V++RPGP Q++K+ +V + T+ W P
Sbjct: 11661 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENP 11720
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
D G + + + V+ W V + I ++L+ N Y FRV AEN+ G+
Sbjct: 11721 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGVGP 11779
Query: 230 TAPITTDLAHI 240
T T + I
Sbjct: 11780 TIETKTPILAI 11790
Score = 89.7 bits (221), Expect = 3e-18
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 4/173 (2%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGC-ALDTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+VG+ L + GKPKP+ W D L+ R ++ L +A+R+DSG+Y
Sbjct: 10526 RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYC 10585
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ V+ + V++RPGPP + +V + W PP D G + + Y ++
Sbjct: 10586 VVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIE 10645
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTD 236
K + +W V +T+C VS L+ G Y FR+ AEN G+S+ P+ +D
Sbjct: 10646 KKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISD--PLVSD 10696
Score = 89.7 bits (221), Expect = 3e-18
Identities = 61/227 (26%), Positives = 105/227 (46%), Gaps = 10/227 (4%)
Query: 5 TAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIE--EHPKIWLPRALRQT 62
T P++ G K + A+ G S + + P+E E P + L L++T
Sbjct: 23098 TVPDLKMGQKYSFRVAAVN-------VKGMSEYSESIAEIEPVERIEIPDLELADDLKKT 23150
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
+ G ++ L++ G+P P W+ G L +R + + E S+L + + R D+G+
Sbjct: 23151 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIVDKVNRYDAGK 23209
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Y + + + +AT+ + V + PGP S+K+ +V S T+ W P G + Y V
Sbjct: 23210 YTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIV 23269
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+K + + TV +T +S L+ G Y FRV EN G+ E
Sbjct: 23270 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 23316
Score = 89.4 bits (220), Expect = 5e-18
Identities = 51/201 (25%), Positives = 96/201 (47%), Gaps = 2/201 (0%)
Query: 31 SPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
S + + S P ++ E P++ + R + K G+ + + G+P P W D
Sbjct: 19462 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19521
Query: 91 GCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
G ++ R R + + + ++L +++ R D+G+Y L ++ + ++ V+++PGPP
Sbjct: 19522 GIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPP 19581
Query: 150 QS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
+++ + +L W PQ+ G + Y V+K +T W TSC V+
Sbjct: 19582 AGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTK 19641
Query: 209 LIIGNSYAFRVFAENQCGLSE 229
L+ GN Y FRV N+ G+ E
Sbjct: 19642 LLKGNEYIFRVTGVNKYGVGE 19662
Score = 87.8 bits (216), Expect = 1e-17
Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 1/163 (0%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLR 126
G+ +++ +PF+ P P W DG + R++++N + L + ++ RAD+G Y +
Sbjct: 8096 GEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTIT 8155
Query: 127 VQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKAD 186
++ ATA+I++ VI PGP + IK D+ S L W PP+ G T +L Y +++ +
Sbjct: 8156 LENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERRE 8215
Query: 187 TKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ V+ ++ S V DLI Y FRV A N+ G E
Sbjct: 8216 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGE 8258
Score = 86.3 bits (212), Expect = 4e-17
Identities = 54/187 (28%), Positives = 92/187 (49%), Gaps = 8/187 (4%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
PKI + Q + VG + +++P+ PK +A W + L T+ + EQ S
Sbjct: 6695 PKI---KTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT-TAEQTSFR 6750
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQ 170
+ EA++ D GRY++ +Q +A I++ VI+ PGP +++++ + + +L W P
Sbjct: 6751 IL-EAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPL 6809
Query: 171 DTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGN-SYAFRVFAENQCGLSE 229
G + ++GY V++ D K W + V+ L G Y FRV A N+ G E
Sbjct: 6810 TDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE 6869
Query: 230 TAPITTD 236
P+ TD
Sbjct: 6870 --PVETD 6874
Score = 84.7 bits (208), Expect = 1e-16
Identities = 69/250 (27%), Positives = 111/250 (44%), Gaps = 13/250 (5%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
++G V+L +P++GKPKP W DG L ++ V E L I+ A++ G+Y
Sbjct: 21271 RIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21330
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ + I ++ + P P+ I+ ++ S L W P+D G + Y+++
Sbjct: 21331 VILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 21390
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
K +T W V RT+ V +L+ Y FRV AEN+ G+S+ + +A Q
Sbjct: 21391 KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFR 21450
Query: 244 ATVYKTKGFAQRDFSEAPKFT--QPLAD-CTTVTGYNTQLFCCVRASPRPKIIWLK-NKM 299
K S+ T P+ D + VTG++ V R I+W K N
Sbjct: 21451 IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFH------VEKKERNSILWQKVNTS 21504
Query: 300 DIQGNPKYRA 309
I G +YRA
Sbjct: 21505 PISGR-EYRA 21513
Score = 82.8 bits (203), Expect = 4e-16
Identities = 56/206 (27%), Positives = 90/206 (43%), Gaps = 15/206 (7%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-TVLEHYHRT 202
++P P ++++ + S TL+W P+ G +LGY V+ + W + E
Sbjct: 24124 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 24183
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+ L+ Y FRVFAEN+ GLS ++ A KTK + EAP
Sbjct: 24184 QFTIGGLLEATEYEFRVFAENETGLSRP----------RRTAMSIKTKLTS----GEAPG 24229
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ + D TT G QL C + P P I W + ++ + KY+ + +L +
Sbjct: 24230 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 24289
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRV 348
D G+YTC A N +GE ++
Sbjct: 24290 EEQEDEGVYTCIATNEVGEVETSSKL 24315
Score = 80.5 bits (197), Expect = 2e-15
Identities = 52/183 (28%), Positives = 93/183 (50%), Gaps = 8/183 (4%)
Query: 59 LRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQR 117
L++ Y VG T+ L + + G+P P W H L ++ +++ N E + L ++ QR
Sbjct: 24329 LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQR 24388
Query: 118 -ADSGRYQLRVQLGGLEAT--ATIDILVIERPGPPQSIKLVD-VWGFSATLEWTPPQDTG 173
+G+Y +VQL + T A +D+ + ++P P +++ + SA + W PP D G
Sbjct: 24389 KTHAGKY--KVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24446
Query: 174 NTALLGYTVQKADTKSGL-WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAP 232
+ + Y V+K + K G W V T+C + +L Y FRV A+N G+S+
Sbjct: 24447 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24506
Query: 233 ITT 235
+++
Sbjct: 24507 VSS 24509
Score = 80.1 bits (196), Expect = 3e-15
Identities = 65/221 (29%), Positives = 96/221 (43%), Gaps = 7/221 (3%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKV--GDTV 71
+L + + DA Q GS + +E KI LP+ L G+ V
Sbjct: 24681 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 24740
Query: 72 NLLIPFQGKPKPQAIWTHDGCALDTR---RVSVRNGEQDSILFIREAQRADSGRYQLRVQ 128
++ IPF GKP P W +D +V V S++F +R D+G Y + +
Sbjct: 24741 SIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAGFYVVCAK 24799
Query: 129 LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTK 188
T+++ V + P PP+ +K+ DV S L WT P G + + Y V+K T
Sbjct: 24800 NRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT 24859
Query: 189 SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ W V T V +L SY FRV AEN+ GLS+
Sbjct: 24860 AERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLSK 24899
Score = 79.0 bits (193), Expect = 6e-15
Identities = 63/231 (27%), Positives = 98/231 (42%), Gaps = 34/231 (14%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIR-KVGDTVNLLIPFQGKPKPQAIW 87
+A G P+ + PP + I P+ + +T + K GD + L G P P W
Sbjct: 8350 RAENAAGISEPS-RATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITW 8408
Query: 88 THDGCALD-----------------------------TRRVSVRNGEQ-DSILFIREAQR 117
D + T+R+S+ N ++ +S L +R++ R
Sbjct: 8409 IKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLR 8468
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTAL 177
D G Y ++V+ A A + V++ PGPP + D+ S +W PP D G + +
Sbjct: 8469 PDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEI 8528
Query: 178 LGYTVQKAD-TK-SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
+ YT++K D TK W V V+ LI G Y FRV AEN+ G
Sbjct: 8529 INYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG 8579
Score = 77.0 bits (188), Expect = 2e-14
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
Query: 79 GKPKPQAIWTHDGCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATAT 137
GKP+P+ IWT LD +VS++ + + I+ R+DSG+Y L V+ +
Sbjct: 22768 GKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS 22827
Query: 138 IDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE 197
+ + V++ PGP + + V TL W+ PQ+ G + Y V++ +T W V
Sbjct: 22828 VMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEG 22887
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
S +V+ LI N Y FRV A N+ G
Sbjct: 22888 ECPTLSYVVTRLIKNNEYIFRVRAVNKYG 22916
Score = 75.5 bits (184), Expect = 7e-14
Identities = 53/193 (27%), Positives = 86/193 (44%), Gaps = 4/193 (2%)
Query: 64 IRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGR 122
I K G+++ + QG+P P+ W DG ++ R + + + + LF+R+A R G
Sbjct: 21664 IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGV 21723
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYT 181
Y + + A A I + V + PG I+ ++ G TL W P + G + Y
Sbjct: 21724 YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYI 21783
Query: 182 VQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQ 241
++K +T W + + S LI GN Y FRV A N+ G+ P+ +D Q
Sbjct: 21784 IEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGR--PLDSDPVVAQ 21841
Query: 242 KAATVYKTKGFAQ 254
TV G +
Sbjct: 21842 IQYTVPDAPGIPE 21854
Score = 74.7 bits (182), Expect = 1e-13
Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 2/178 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
P + L ++R + G + ++ GKP P W + L + ++ S +
Sbjct: 10217 PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP-QEATIETTAISSSM 10275
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLV-DVWGFSATLEWTPP 169
I+ QR+ G Y L + E TI + V++ PGP + L ++ S L W P
Sbjct: 10276 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10335
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
+D G + + Y ++K ++ W V R + V LI G +Y FR+ AEN G+
Sbjct: 10336 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGM 10393
Score = 74.3 bits (181), Expect = 2e-13
Identities = 56/212 (26%), Positives = 86/212 (40%), Gaps = 16/212 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A + ERP PP I L+DV S +L W P+ G + +LGY V+ S
Sbjct: 15729 GLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSD 15788
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W T T ++ LI G Y+FRV A+N+ G+S+ ++ +
Sbjct: 15789 KWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPV------------- 15834
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
+D P F T + G + ++ P P + W K+ + ++ + A
Sbjct: 15835 --IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE 15892
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
+ L I+ D G Y K N GEA
Sbjct: 15893 STENNSLLTIKDACREDVGHYVVKLTNSAGEA 15924
Score = 74.3 bits (181), Expect = 2e-13
Identities = 55/216 (25%), Positives = 87/216 (40%), Gaps = 20/216 (9%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEH 198
+L I+ PP+++++ D+ S +L W P G + + GY V++ D G W +
Sbjct: 20457 VLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTN 20516
Query: 199 YHRTSCIVSDLIIGNSYAFRVFAENQCG-LSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
T I+S L + Y FRVFA N G +S + + + I D
Sbjct: 20517 VTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI---------------DS 20561
Query: 258 SEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
P PL V G + +L + P P I W K+ ++Q N
Sbjct: 20562 YGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD 20621
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ S+ I+ + G Y K N +G AS RV +
Sbjct: 20622 LASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 20657
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/226 (24%), Positives = 95/226 (42%), Gaps = 22/226 (9%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNL 73
+ +VK + A P A+ G P + P I+ L++ + G VN+
Sbjct: 9783 EFRVKAVNAAGVSKPSATVGP-CDCQRPDMPPSID----------LKEFMEVEEGTNVNI 9831
Query: 74 LIPFQGKPKPQAIW---------THDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+ +G P P W + DT V+ + L I +++R+D+G Y
Sbjct: 9832 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTH-VNKLVVDDTCTLVIPQSRRSDTGLYT 9890
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ A+ + + V+ RPGPP IK V TL W PP+D G + + Y ++
Sbjct: 9891 ITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIE 9950
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
K + W V + + L+ G+ Y FR+ A+N+ G+ E
Sbjct: 9951 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9996
Score = 73.6 bits (179), Expect = 3e-13
Identities = 58/209 (27%), Positives = 91/209 (43%), Gaps = 20/209 (9%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH--YHRTS 203
PGPP + ++VD S +L WT P G T ++GY ++ + + W+ V + T
Sbjct: 23037 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 23096
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V DL +G Y+FRV A N G+SE + ++ +++ + ++ K
Sbjct: 23097 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIE-------IPDLELADDLKK 23149
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL--THLGICSLEIR 321
T T G + +L V P P I W K +D+ RA+ T L +
Sbjct: 23150 T-----VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS----RAIIDTTESYSLLIVD 23200
Query: 322 KPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
K +D G YT +A N G+ S V V
Sbjct: 23201 KVNRYDAGKYTIEAENQSGKKSATVLVKV 23229
Score = 72.8 bits (177), Expect = 4e-13
Identities = 58/208 (27%), Positives = 87/208 (41%), Gaps = 18/208 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP+++K D S L W PP++ G + + GY V++ S W E T
Sbjct: 7283 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 7342
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF-- 263
V+ L G YA+RV A N+ G S+ + T ++ + D EAP+
Sbjct: 7343 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAV---------------DTQEAPEIFL 7387
Query: 264 -TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ LA T G +L V P PKI W K M ++ + + ++ I
Sbjct: 7388 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVD 7447
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y +AVN G A+ V+V
Sbjct: 7448 SKRSDTGTYIIEAVNVCGRATAVVEVNV 7475
Score = 71.6 bits (174), Expect = 1e-12
Identities = 49/218 (22%), Positives = 86/218 (39%), Gaps = 16/218 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A I V E P PP I + DV S +L WT P+ G + ++ Y V+ S
Sbjct: 16811 GLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE 16870
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W + ++++L G Y FRV A N+ G S+ + +
Sbjct: 16871 KW-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPI------------- 16916
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
+D P + + G + ++ + P+P I W K+ + ++ +
Sbjct: 16917 --VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT 16974
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
L + +L I++ DGG Y N +G+ + +
Sbjct: 16975 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEI 17012
Score = 69.7 bits (169), Expect = 4e-12
Identities = 59/213 (27%), Positives = 82/213 (38%), Gaps = 16/213 (7%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRT 202
E+PG P + V S + W PP G + Y ++K + K W +V E T
Sbjct: 24518 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24577
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
V +LI G Y FRV EN G SE + I+ + +AP
Sbjct: 24578 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPI-------------QAPH 24624
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHL-GICSLEI 320
F + L + N L C V P+P + W + K I KYR G L I
Sbjct: 24625 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLII 24684
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D +Y +A N G S ++V+VP
Sbjct: 24685 ASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 24717
Score = 69.3 bits (168), Expect = 5e-12
Identities = 59/215 (27%), Positives = 88/215 (40%), Gaps = 17/215 (7%)
Query: 137 TID-ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
T+D + E P PP + L DV SA+L W P+ G + +LGY V+ + W V
Sbjct: 17898 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 17957
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR 255
E + +V+ L G Y FRV A N+ G S+ P + I K T+
Sbjct: 17958 AES-KVCNAVVTGLSSGQEYQFRVKAYNEKGKSD--PRVLGVPVIAKDLTI--------- 18005
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
P P + G + ++ V PRP I W+K+ ++ +
Sbjct: 18006 ----QPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATS 18061
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I++ D G YT A N G A+ + V V
Sbjct: 18062 TVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18096
Score = 68.9 bits (167), Expect = 6e-12
Identities = 60/212 (28%), Positives = 85/212 (40%), Gaps = 23/212 (10%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT---VLEHY 199
I +P PP + + +D S L W PP+ G + +LGY V+ W E
Sbjct: 10805 IAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESC 10864
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
T V+ L G +Y FRV A N G S D AH+ + V +D E
Sbjct: 10865 PETKYKVTGLRDGQTYKFRVLAVNAAGES-------DPAHVPEPVLV--------KDRLE 10909
Query: 260 APKF---TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC 316
P+ + G +L ++ P PK+ W K D + +T +G
Sbjct: 10910 PPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARI-DVTPVG-S 10967
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
LEIR DGGIY+ NP G +V +V
Sbjct: 10968 KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKV 10999
Score = 67.8 bits (164), Expect = 1e-11
Identities = 76/309 (24%), Positives = 123/309 (39%), Gaps = 41/309 (13%)
Query: 48 EEHPKIWLPRALRQTYIR-KVGDTVNLLIPFQGKPKPQAIWTHDGC-------ALDTRRV 99
E P I L ++R I+ K G+ V++ G P P+ W+ + AL +
Sbjct: 9087 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 9146
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWG 159
V E + L I +A R D G Y + + + V +RP PP+++ + D+
Sbjct: 9147 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKA 9206
Query: 160 FSATLEWTPPQDTGNTALLGYTVQKADT--KSGLWFTVLEHYHRTSCIVSDLIIGNSYAF 217
S L W P D G + + Y + K D K W V + LI Y F
Sbjct: 9207 ESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEF 9266
Query: 218 RVFAENQCGLSETAPITTDLAHIQKAATV----YKTKGFAQRDFSEAPKFTQPLAD-CTT 272
RV A N+ G+S+ +D IQ + K K A+ S +T PL + +
Sbjct: 9267 RVRAVNKYGISDEC--KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSP 9324
Query: 273 VTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKY-----RALTHLGICSLEIRKPGPFD 327
+TGY WL+ + +G+P + +T +G+ +E P +
Sbjct: 9325 ITGY-----------------WLEKRE--EGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 9365
Query: 328 GGIYTCKAV 336
G Y +A+
Sbjct: 9366 GVKYQFRAM 9374
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/216 (27%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF------ 193
+LV E P P +++VDV + TL W P G + L GY ++ + W
Sbjct: 23324 VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLK 23383
Query: 194 -TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGF 252
TVLEH V+ L G Y FR+ A+N+ G+SE T A TV +
Sbjct: 23384 PTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETVT-------AVTVQDLRVL 23430
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTH 312
D S T P G +L + P P W ++ + + TH
Sbjct: 23431 PTIDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH 23485
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
+ L IR+ D G YT + N G S +V
Sbjct: 23486 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23521
Score = 67.0 bits (162), Expect = 2e-11
Identities = 57/213 (26%), Positives = 88/213 (41%), Gaps = 22/213 (10%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHR 201
IERP PP ++ D S L+W PP G + +LGY +++ + W ++
Sbjct: 6984 IERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPE 7043
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETA----PITTDLAHIQKAATVYKTKGFAQRDF 257
+ V+ L GN Y +RV AEN+ G+S+ + P+T D A ++ + A +D
Sbjct: 7044 LTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDL-----SAFKDG 7098
Query: 258 SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
E P+ TGY PRP W ++ + + T
Sbjct: 7099 LEV-IVPNPITILVPSTGY-----------PRPTATWCFGDKVLETGDRVKMKTLSAYAE 7146
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I D GIYT K N + S + V+V
Sbjct: 7147 LVISPSERSDKGIYTLKLENRVKTISGEIDVNV 7179
Score = 67.0 bits (162), Expect = 2e-11
Identities = 52/220 (23%), Positives = 82/220 (37%), Gaps = 16/220 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A T + V E P PP + LVDV +AT++W P+ G + + GY V+ S
Sbjct: 18976 GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSE 19035
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W T + +S L G Y FRV A N+ G S+ + +
Sbjct: 19036 KWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV------------- 19081
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
RD P P ++ + P+ + W K+ ++ +
Sbjct: 19082 --IARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVS 19139
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + SL I++ D G Y N G +V + V
Sbjct: 19140 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19179
Score = 66.6 bits (161), Expect = 3e-11
Identities = 59/215 (27%), Positives = 88/215 (40%), Gaps = 21/215 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE--HYH 200
I+ PGPP I++ D S TL W+ P G +A+ GY V+ + W TV
Sbjct: 20859 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20918
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
T +VS+L G +Y FRV A N G E + + +D EA
Sbjct: 20919 TTEYVVSNLKPGVNYYFRVSAVNCAGQGE---------------PIEMNEPVQAKDILEA 20963
Query: 261 PKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P+ +A T+V G + Q+ + P P + W K++ ++ + +Y
Sbjct: 20964 PEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL 21023
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
L I + D G Y N +GE V VKV
Sbjct: 21024 LTIPQVTRNDTGKYILTIENGVGEPK-SSTVSVKV 21057
Score = 65.9 bits (159), Expect = 5e-11
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 19/211 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHR 201
+ PGPP +K+ D + +LEW+ P G ++GY ++ G W V E +
Sbjct: 21946 VNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVK 22005
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
T V+DL G Y FRV A N G ++ +T + + + + D
Sbjct: 22006 TRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTA-------PELDIDANF 22058
Query: 262 KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL--GICSLE 319
K T + G + +LF + P P +W K N RA H +L
Sbjct: 22059 KQTHVVR-----AGASIRLFIAYQGRPTPTAVWSKP----DSNLSLRADIHTTDSFSTLT 22109
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ D G YT N G S+ V V
Sbjct: 22110 VENCNRNDAGKYTLTVENNSGSKSITFTVKV 22140
Score = 63.9 bits (154), Expect = 2e-10
Identities = 57/217 (26%), Positives = 87/217 (40%), Gaps = 21/217 (9%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY 199
++ ++ PP +++++ S TL WT P+ G L GY V+K D S W H
Sbjct: 13963 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKA-NHV 14021
Query: 200 HRTSC--IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
+ C V+DL+ G Y FR+ A+N G +A T+ +D
Sbjct: 14022 NVPECAFTVTDLVEGGKYEFRIRAKNTAGAI--------------SAPSESTETIICKDE 14067
Query: 258 SEAPKFT--QPLADCTTVTGYNTQLF--CCVRASPRPKIIWLKNKMDIQGNPKYRALTHL 313
EAP + D T+ +T + + P PK W K DI+ + + +
Sbjct: 14068 YEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTP 14127
Query: 314 GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I+ D G YT A NP G +V V
Sbjct: 14128 TSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 14164
Score = 63.5 bits (153), Expect = 3e-10
Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 26/215 (12%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW--FTVLEHYH 200
I +PGPP + K++D+ S L W+ P G + GY V+K D G W T +
Sbjct: 16530 IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGIN 16589
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
+T+ V L+ + Y FR+ A N+ G+ E A + + +K EA
Sbjct: 16590 KTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL---------------EA 16634
Query: 261 PKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL--GI 315
P L + G + +LF ++ P P++ W K + G + A+ +
Sbjct: 16635 PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGK----VDGEIRDAAIIDVTSSF 16690
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
SL + +D G YT N G S V V
Sbjct: 16691 TSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRV 16725
Score = 63.2 bits (152), Expect = 3e-10
Identities = 66/274 (24%), Positives = 113/274 (41%), Gaps = 40/274 (14%)
Query: 101 VRNGEQDSILFIREAQRADSGR------------YQLRVQL---GGLEATA-----TIDI 140
V E++SIL+ + SGR YQ RV GL + + T+ +
Sbjct: 21488 VEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAV 21547
Query: 141 LVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYH 200
++ PG P I DV + TL+W PP G + ++GY+++K
Sbjct: 21548 SPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVS 21604
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
V+ L G+ Y FR+ A N G ++ +++ + T RD +
Sbjct: 21605 ECQYTVTGLSPGDRYEFRIIARNAVG---------TISPPSQSSGIIMT-----RDENVP 21650
Query: 261 P--KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P +F D + +G + ++ V+ P P++ W K+ ++I+ LG S
Sbjct: 21651 PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTS 21710
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L +R G+YT +A N G A + +V V+
Sbjct: 21711 LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744
Score = 62.0 bits (149), Expect = 8e-10
Identities = 31/88 (35%), Positives = 48/88 (54%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP+ ++++++ +A L+WT P+ G + + Y V+K D + W TV T C
Sbjct: 7779 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7838
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPI 233
V+ L G+ Y FRV AEN G S+ I
Sbjct: 7839 VTPLTEGSLYVFRVAAENAIGQSDYTEI 7866
Score = 61.2 bits (147), Expect = 1e-09
Identities = 56/213 (26%), Positives = 81/213 (38%), Gaps = 20/213 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRT 202
I+ PGPP + KL D +A L WT P G + +LGY V+ + W + +
Sbjct: 11496 IKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIR 11555
Query: 203 SCI--VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
C V LI GN Y FR+ A N G E + + +D
Sbjct: 11556 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL---------------AESVIAKDILHP 11600
Query: 261 PKFTQPLA--DCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P+ + D TV G ++ V+ P P I W K + + + L
Sbjct: 11601 PEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE 11660
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L+I++ D G Y A N G A V+V
Sbjct: 11661 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNV 11693
Score = 60.8 bits (146), Expect = 2e-09
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 9/142 (6%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
+EA + D+ PGPP ++ + DV F +L W PP+ G + Y ++ D S
Sbjct: 6877 VEARSKYDV-----PGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIR 6931
Query: 192 WFTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGL---SETAPITTDLAHIQKAATVY 247
W T + S V+D++ G Y+FRV A+N+ G+ S P I++ +
Sbjct: 6932 WDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPV 6991
Query: 248 KTKGFAQRDFSEAPKFTQPLAD 269
Q S K+ PL D
Sbjct: 6992 NLTSSDQTQSSVQLKWEPPLKD 7013
Score = 59.7 bits (143), Expect = 4e-09
Identities = 61/221 (27%), Positives = 83/221 (37%), Gaps = 32/221 (14%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ------KADTKSGLW--FT 194
IE PGPP + ++VD S TL W P G ++GY V+ A G W
Sbjct: 12189 IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEG-WKRCN 12247
Query: 195 VLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQ 254
R V+ L Y FRV A+NQ G+ A + +
Sbjct: 12248 AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAEL---------------KEAIKP 12292
Query: 255 RDFSEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
++ E P+ + V G +LF VR P PK+ W K +D N +
Sbjct: 12293 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID---NVVRKGQV 12349
Query: 312 HL--GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L + L I D G Y+ VNP GE +V V V
Sbjct: 12350 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRV 12390
Score = 59.7 bits (143), Expect = 4e-09
Identities = 66/250 (26%), Positives = 94/250 (37%), Gaps = 30/250 (12%)
Query: 114 EAQRADSG-RYQLRVQ----LGGLEATATIDILVIERP-GPPQSIKLVDVWGFSATLEWT 167
+AQ + G Y+ RV +G +A+ + V P PP + + + V TL+WT
Sbjct: 17178 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 17237
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
P G + + GY V+K D G W + T VS L Y FRV A+N G
Sbjct: 17238 KPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG 17297
Query: 227 L-----SETAPITT-DLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQL 280
T PIT D + + S PKF + G +L
Sbjct: 17298 AISKPSDSTGPITAKDEVELPR--------------ISMDPKFRDTI---VVNAGETFRL 17340
Query: 281 FCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
V P P I WL+ +I+ + + L ++ DGG Y +A N G
Sbjct: 17341 EADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 17400
Query: 341 EASVDCRVDV 350
S V V
Sbjct: 17401 SKSFPVNVKV 17410
Score = 59.3 bits (142), Expect = 5e-09
Identities = 46/207 (22%), Positives = 76/207 (36%), Gaps = 17/207 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR--TS 203
P PP + + D + W PP+ G + ++GY V+ + W V +
Sbjct: 7980 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 8039
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
+ ++ Y RV A N G+SE + I+ ++ +D P
Sbjct: 8040 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV---------------VAKDPDCKPTI 8084
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
D + G + RA P P + W K+ +++ + + LE+ K
Sbjct: 8085 DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKS 8144
Query: 324 GPFDGGIYTCKAVNPLGEASVDCRVDV 350
D GIYT N LG A+ V V
Sbjct: 8145 VRADAGIYTITLENKLGSATASINVKV 8171
Score = 59.3 bits (142), Expect = 5e-09
Identities = 56/225 (24%), Positives = 88/225 (39%), Gaps = 30/225 (13%)
Query: 135 TATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT 194
T + I I+RPG P+++ + D L+W P G + L Y V++ S W
Sbjct: 11785 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER 11844
Query: 195 VLE------HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYK 248
V + HY C+ + + Y FRV +N+ G S+ K
Sbjct: 11845 VHKGSIKETHYMVDRCVENQI-----YEFRVQTKNEGGESDWV----------------K 11883
Query: 249 TKGFAQRDFSEAPKFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNK--MDIQGNP 305
T+ ++ + P L+ TV G +L VR P P++ W K+K D+ +P
Sbjct: 11884 TEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP 11943
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + T + K DGG Y A N G V+V
Sbjct: 11944 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11988
Score = 59.3 bits (142), Expect = 5e-09
Identities = 49/210 (23%), Positives = 78/210 (37%), Gaps = 15/210 (7%)
Query: 133 EATATID-ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
E T T + + E P PP S+ ++D+ + +L W P+ G + + GY ++ S
Sbjct: 14646 EPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 14705
Query: 192 WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKG 251
W T + C+V +L G Y F+V A N G S + Q +G
Sbjct: 14706 W-THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRG 14764
Query: 252 FAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
Q+ G N ++ V P+P + W K ++ + T
Sbjct: 14765 IYQK-------------LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFET 14811
Query: 312 HLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
L I + D G Y A N +GE
Sbjct: 14812 TATSTILNINECVRSDSGPYPLTARNIVGE 14841
Score = 58.9 bits (141), Expect = 7e-09
Identities = 52/208 (25%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP + + V S TL+W P G + + GY V+K + G W + T V
Sbjct: 16136 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEV 16195
Query: 207 SDLIIGNSYAFRVFAENQCGL-SETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
+ L+ + Y FRV A N G+ SE + T RD + P+ +
Sbjct: 16196 TGLVEDHRYEFRVIARNAAGVFSEPSE---------------STGAITARDEVDPPRISM 16240
Query: 266 PLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
T+ G + ++ + P P I W+K ++ + + SL ++
Sbjct: 16241 DPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKD 16300
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y KA N GE SV V V
Sbjct: 16301 AVRVDSGNYILKAKNVAGERSVTVNVKV 16328
Score = 58.5 bits (140), Expect = 9e-09
Identities = 51/212 (24%), Positives = 77/212 (36%), Gaps = 35/212 (16%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY 199
I+ E+P PP+ + +VD SA L W P G + + GY ++ S W H
Sbjct: 22235 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHT 22293
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
+ + V L+ Y FRV A+N G SE + F+ E
Sbjct: 22294 KQLTFTVERLVEKTEYEFRVKAKNDAGYSE------------------PREAFSSVIIKE 22335
Query: 260 APKFTQPLADCTTVTGYNTQLFCC-----------VRASPRPKIIWLKNKMDIQGNPKYR 308
+P AD +TG QL C + P PK+ W +M ++ +
Sbjct: 22336 PQ--IEPTAD---LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS 22390
Query: 309 ALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
T +L ++ D G Y N G
Sbjct: 22391 ITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 22422
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/218 (24%), Positives = 81/218 (37%), Gaps = 29/218 (13%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ-----KADTKSGLWFTVLEH-Y 199
P PP +K+ + + L W PP++ G + + Y V+ TK W +
Sbjct: 9707 PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDV 9766
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
V DL+ G Y FRV A N G+S+ + T G +
Sbjct: 9767 EELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS----------------ATVGPCDCQRPD 9810
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-------NKMDIQGNPKYRALTH 312
P G N + ++ P P + W K NK + + L
Sbjct: 9811 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVV 9870
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
C+L I + D G+YT AVN LG AS + R++V
Sbjct: 9871 DDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9908
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/208 (25%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP K+VD + T+ W P G + GYTV+ + W T ++ T
Sbjct: 19779 PSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYT 19838
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF-- 263
+S L G Y FRV + N+ G S+ +D + Q A ++ E P F
Sbjct: 19839 ISGLTTGAEYVFRVKSVNKVGASD----PSDSSDPQIA-----------KEREEEPLFDI 19883
Query: 264 -TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
++ G + + R P P ++W K D++ + T SL I
Sbjct: 19884 DSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLR--TRAYVDTTDSRTSLTIEN 19941
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G YT N L AS+ V V
Sbjct: 19942 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19969
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/212 (21%), Positives = 86/212 (40%), Gaps = 17/212 (8%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
G+ A + + E+P PP+ + + + S +L W P+ G + ++ Y V+ +
Sbjct: 20055 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20114
Query: 191 LWF--TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYK 248
W V + H +VS L + Y FRVFAENQ GLS+ + + ++
Sbjct: 20115 NWVKCAVAKSTHH---VVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEP--- 20168
Query: 249 TKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR 308
+ D P T + G N ++ + P PK+ ++ + ++ ++
Sbjct: 20169 ----PEIDMKNFPSHTVYVR-----AGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFN 20219
Query: 309 ALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
++ +++ D G Y A N G
Sbjct: 20220 TEITAENLTINLKESVTADAGRYEITAANSSG 20251
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 10/106 (9%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L++T T+ P PP + D+ +AT+ WT P+ G + + GY +++ + +G
Sbjct: 11385 LDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREV-TGK 11443
Query: 192 WFTVLEHYHRTSCI-----VSDLIIGNSYAFRVFAENQCGLSETAP 232
W V ++T V+ L GN+Y FRVFAEN GLS+ +P
Sbjct: 11444 WVRV----NKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSP 11485
Score = 57.8 bits (138), Expect = 1e-08
Identities = 55/208 (26%), Positives = 79/208 (37%), Gaps = 29/208 (13%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-----TVLE 197
I+ PG P + + + TL+W P+ TG + Y V+K D +G W +LE
Sbjct: 15052 IDPPGKPVPLNITR---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 15108
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
+ S + D +Y FRV A+N G +D RD
Sbjct: 15109 NEFTVSGLTEDA----AYEFRVIAKNAAGAISPPSEPSD--------------AITCRDD 15150
Query: 258 SEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
EAPK + TV G +L V P P + W K+ +++G K
Sbjct: 15151 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15210
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
+L + D G YT A NP G A
Sbjct: 15211 STNLVNKDSTRRDSGAYTLTATNPGGFA 15238
Score = 56.6 bits (135), Expect = 3e-08
Identities = 46/200 (23%), Positives = 78/200 (39%), Gaps = 17/200 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF--TVLEHYHRTS 203
PGPP + + D SA+L W P G + GY V+ W T T
Sbjct: 14368 PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQ 14427
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
+V DL Y FR+ A N G+ E A + D+ +++ DF +
Sbjct: 14428 FVVPDLQTKEKYNFRISAINDAGVGEPA-VIPDVEIVEREMA---------PDFELDAEL 14477
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
+ L G + ++F ++ P P++ W K+ ++++ + L I +
Sbjct: 14478 RRTL---VVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--LIIPEC 14532
Query: 324 GPFDGGIYTCKAVNPLGEAS 343
+D G + NP G+ S
Sbjct: 14533 NRYDTGKFVMTIENPAGKKS 14552
Score = 55.8 bits (133), Expect = 6e-08
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTSC 204
PGPP+ ++ +V +AT+ W P D G + + GY V++ + KS W ++ C
Sbjct: 14267 PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 14326
Query: 205 IVSDLIIGNSYAFRVFAENQCGL 227
V+ L G++Y FRV AEN+ G+
Sbjct: 14327 KVTGLQEGSTYEFRVSAENRAGI 14349
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/223 (25%), Positives = 88/223 (39%), Gaps = 22/223 (9%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
G T + E P P + + + D S L WT P G + + Y V++
Sbjct: 21143 GEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQ 21202
Query: 191 LWFTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKT 249
W +T I VS L + FRVFA+N+ GLS+ P+T +++ +
Sbjct: 21203 TWSHA--GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD--PVTIGPITVKELIITPEV 21258
Query: 250 KGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA 309
D S+ P A T G+N L + P+P I WLK+ + ++ + R
Sbjct: 21259 ------DLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRF 21307
Query: 310 LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
+L I+ GG YT N + CR+ V +
Sbjct: 21308 SKTENKITLSIKNAKKEHGGKYTVILDNAV------CRIAVPI 21344
Score = 54.7 bits (130), Expect = 1e-07
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 14/159 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ--KADTKSGLWFTVLEHYHRTS 203
PGPP K+ D S +L W P G + ++GY V+ +AD+ + + + ++ +T
Sbjct: 13284 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13343
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V+ L+ Y FRV+A N+ G S+ + + H K + +G D +
Sbjct: 13344 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPD--KHYPKDILI-PPEGELDADLRKT--- 13397
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ 302
G +L+ V+ P PKI W K ++++
Sbjct: 13398 ------LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLR 13430
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query: 146 PGPPQSI-KLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTS 203
P PP + +++DV S +L W+ P+D G + + GY +++ +T + W + T
Sbjct: 24024 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 24083
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAP 232
V+ L+ Y FR+ A+N GLSET+P
Sbjct: 24084 YTVTGLVPDAEYQFRIIAQNDVGLSETSP 24112
Score = 53.9 bits (128), Expect = 2e-07
Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP+S+++ ++ S T+ W P G + ++GY V+K D +SG+ + T
Sbjct: 17514 PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRD-RSGIRWIKCNKRRITDLR 17572
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
V+ L + Y FRV AEN G+ E +P T
Sbjct: 17573 LRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 17603
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 3/136 (2%)
Query: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTG 275
AF+ E +SET +D + T KT+ A S P L D T +
Sbjct: 26505 AFKSIHEKVSKISETKK--SDQKTTESTVT-RKTEPKAPEPISSKPVIVTGLQDTTVSSD 26561
Query: 276 YNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
+ PRP IW K+ I KY+ G LEI K D G+YTC
Sbjct: 26562 SVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTV 26621
Query: 336 VNPLGEASVDCRVDVK 351
N G S C++ +K
Sbjct: 26622 KNSAGSVSSSCKLTIK 26637
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Query: 131 GLEATATIDILV---IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADT 187
G + +T IL+ I+ P PP + DV S L WT P+ G + Y ++ T
Sbjct: 7661 GKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKT 7720
Query: 188 KSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ W V E T ++ L+ G Y+FRV A N+ G SE
Sbjct: 7721 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESE 7762
Score = 52.8 bits (125), Expect = 5e-07
Identities = 27/92 (29%), Positives = 41/92 (44%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P L + T + G + L C + P P + W + I+ + ++ GI L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
R+ D G +TC AVN G S C + V+V
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/211 (25%), Positives = 80/211 (37%), Gaps = 24/211 (11%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
PG P++I + + TL+W P G + + GY V+K D G W + T
Sbjct: 18301 PGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEF 18357
Query: 205 IVSDLIIGNSYAFRVFAENQCG-LSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP-- 261
VS L+ Y FRV A N G SE + + RD +AP
Sbjct: 18358 TVSGLVEDQRYEFRVIARNAAGNFSEPSD---------------SSGAITARDEIDAPNA 18402
Query: 262 KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGN-PKYRALTHLGICSLE 319
D V G L +R P P ++W K+ +++ + + + +L
Sbjct: 18403 SLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLV 18462
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
++ DGG Y K N G S+ V V
Sbjct: 18463 VKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18493
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 9/125 (7%)
Query: 114 EAQRADSG-RYQLRVQLG-------GLEATATIDILVIERPGPPQSIKLVDVWGFSATLE 165
+A R +G YQ RV+ G+ + + + PGPP + ++ V S T+
Sbjct: 14914 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 14973
Query: 166 WTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD-LIIGNSYAFRVFAENQ 224
W P G + +LGY V++ + LW TV + + S L G +Y FRV AEN
Sbjct: 14974 WHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENM 15033
Query: 225 CGLSE 229
G S+
Sbjct: 15034 AGKSK 15038
Score = 50.8 bits (120), Expect = 2e-06
Identities = 55/235 (23%), Positives = 82/235 (34%), Gaps = 46/235 (19%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRTSC 204
P PP +++ + + T+ W PP G + ++GY ++K W EH +
Sbjct: 8275 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8334
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
L G Y FRV AEN G+SE + T + D +APK
Sbjct: 8335 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV---------------DPIDAPKVI 8379
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNK-MDIQGNPKYRALTHLGICSLEIRKP 323
G L + SP P I W+K++ + + K RA + E+++
Sbjct: 8380 L-RTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 8438
Query: 324 GPF----------------------------DGGIYTCKAVNPLGEASVDCRVDV 350
PF D G+Y K N G A C V V
Sbjct: 8439 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8493
Score = 50.8 bits (120), Expect = 2e-06
Identities = 55/221 (24%), Positives = 84/221 (38%), Gaps = 33/221 (14%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH---YHRT 202
PGPP ++ D S +L W PP G + + GY V+ + + W V E
Sbjct: 9400 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9459
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDL--AHIQKAATVYKTKGFAQRDFSEA 260
C+V +L Y FRV A N+ G SE + T ++ IQ+ V+ G
Sbjct: 9460 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIG--------- 9510
Query: 261 PKFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIW-----LKNKM-----DIQGNPKYRA 309
DC G ++ ++ P PK W K M DI + +
Sbjct: 9511 ------AQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLET 9564
Query: 310 LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + + K G Y+ A N G+ + +CRV V
Sbjct: 9565 AENSSVIIIPECKRS--HTGKYSITAKNKAGQKTANCRVKV 9603
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 20/211 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR- 201
I PGPP K+ D SA LEW+PP G + + GY V+ + W + R
Sbjct: 10114 IAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 10172
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
T +V+ L G Y FRV A N G+ E + TD+ ++ R S
Sbjct: 10173 TKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEV-TDVIEMK------------DRLVSPDL 10219
Query: 262 KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI-CSLE 319
+ + D V G ++ V P P + W N+ + P+ + I S+
Sbjct: 10220 QLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL---PQEATIETTAISSSMV 10276
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I+ G+Y+ A N GE VDV
Sbjct: 10277 IKNCQRSHQGVYSLLAKNEAGERKKTIIVDV 10307
Score = 50.8 bits (120), Expect = 2e-06
Identities = 52/206 (25%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PGPP+ + VDV +L W P G + + GY V+ + + W + C+
Sbjct: 11105 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECV 11163
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
V+ L G +Y FRV AEN GL P TT Q ++ + +
Sbjct: 11164 VTGLQQGKTYRFRVKAENIVGLG--LPDTTIPIECQ------------EKLVPPSVELDV 11209
Query: 266 PLADCTTVTGYNTQLF-CCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
L + V T F +R P P W + +I+ + Y T L I+
Sbjct: 11210 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCL 11269
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y N G +V + V
Sbjct: 11270 RRDTGEYQITVSNAAGSKTVAVHLTV 11295
Score = 50.8 bits (120), Expect = 2e-06
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
P PP S+++ V S TL W+ P+ G + + GY +++ + S W V + +
Sbjct: 19678 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 19737
Query: 205 IVSDLIIGNSYAFRVFAENQCGL---SETAPI 233
+ L G Y +RV+AEN GL SET+P+
Sbjct: 19738 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19769
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PGPP + + +V S T+ W P G +A++GY ++ D S LW + RT+
Sbjct: 20365 PGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHF 20424
Query: 206 -VSDLIIGNSYAFRVFAENQCGLSE 229
V+ + G Y FRV+AEN G+ +
Sbjct: 20425 KVTTISAGLIYEFRVYAENAAGVGK 20449
Score = 49.7 bits (117), Expect = 4e-06
Identities = 54/223 (24%), Positives = 89/223 (39%), Gaps = 27/223 (12%)
Query: 137 TIDILVIERP----GPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
T + LVI P P+ +++ +V + TL W PP+ G + ++ Y ++ + +
Sbjct: 10399 TSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10458
Query: 193 FTVL-EHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE----TAPITTDLAHIQKAATVY 247
V ++ V L G++Y +RV A N G + T PIT K
Sbjct: 10459 HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITC------KDELAP 10512
Query: 248 KTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKY 307
T RD K T + + +TG + P+PK+ W K++ D+ + +
Sbjct: 10513 PTLHLDFRD-----KLTIRVGEAFALTGRYS-------GKPKPKVSWFKDEADVLEDDRT 10560
Query: 308 RALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
T +LE K D G Y N G C+V+V
Sbjct: 10561 HIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10603
Score = 49.7 bits (117), Expect = 4e-06
Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 11/90 (12%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV------L 196
I PGPP+++++ DV TL W PP+D G + + GY V++ + ++ W V +
Sbjct: 23624 IRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTM 23683
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
Y T L G Y RV A N G
Sbjct: 23684 TRYRSTG-----LTEGLEYEHRVTAINARG 23708
Score = 49.3 bits (116), Expect = 5e-06
Identities = 51/209 (24%), Positives = 80/209 (38%), Gaps = 17/209 (8%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY-TVQKADTKSGLWFTVLEHYHR 201
+ P PP+ +++ ++ SATL W PP G + GY T + + + +T
Sbjct: 12491 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD 12550
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
S +V+ L G Y FRV A N G+S ++A VY+ K + P
Sbjct: 12551 LSLVVTGLKEGKKYKFRVAARNAVGVSLP----------REAEGVYEAK-----EQLLPP 12595
Query: 262 KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIR 321
K P T G ++ V P P W K + ++ + L I+
Sbjct: 12596 KILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 12654
Query: 322 KPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y+ A N G + +V V
Sbjct: 12655 DVTRKDSGYYSLTAENSSGTDTQKIKVVV 12683
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP + ++ + S + W P D G T + GY ++K D K G+ +T T
Sbjct: 18597 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRD-KEGVRWTKCNKKTLTDLR 18655
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSE 229
V+ L G+SY FRV AEN G+ E
Sbjct: 18656 LRVTGLTEGHSYEFRVAAENAAGVGE 18681
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
A I V + PG P+ + G S TL W P+ G + + Y +++ + KS W V
Sbjct: 21840 AQIQYTVPDAPGIPEPSNIT---GNSITLTWARPESDGGSEIQQYILERREKKSTRWVKV 21896
Query: 196 LEH--YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
+ T V+ L GN Y F V AEN G+ + I+
Sbjct: 21897 ISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGIS 21937
Score = 49.3 bits (116), Expect = 5e-06
Identities = 58/232 (25%), Positives = 90/232 (38%), Gaps = 57/232 (24%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK---ADTKSGLW----FTV 195
++ PG P+ + DV + +L W+ P G + ++GY +++ ++ G W +T+
Sbjct: 22634 VDAPGRPE---VTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTI 22690
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL-----SETAPITTDLAHIQKAATVYKTK 250
+ T +S+ G++Y FRV A+N G+ T P+T
Sbjct: 22691 VSDNFFTVTALSE---GDTYEFRVLAKNAAGVISKGSESTGPVTC--------------- 22732
Query: 251 GFAQRDFSEAPKF---TQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLK--------NK 298
RD PK + D T+ G + L V P PKIIW K K
Sbjct: 22733 ----RDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK 22788
Query: 299 MDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ +Q K RA + C D G YT N G +V V V
Sbjct: 22789 VSLQYTGK-RATAVIKFCDRS-------DSGKYTLTVKNASGTKAVSVMVKV 22832
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/214 (25%), Positives = 84/214 (39%), Gaps = 25/214 (11%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV--QKAD----TKSGLWFTVL 196
I PG PQ+ ++ D S +L W+ P+D G + + GY + QK D TK T +
Sbjct: 23725 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 23784
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRD 256
Y ++ L G Y FRV A N G E A + TV T+ D
Sbjct: 23785 REY-----TLTHLPQGAEYRFRVLACNAGGPGEPAEV---------PGTVKVTEMLEYPD 23830
Query: 257 FSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC 316
+ ++ + + G +L ++ P P W K DI + + T
Sbjct: 23831 YELDERYQEGI---FVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHT 23885
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I++ D G Y N G+ +V +V V
Sbjct: 23886 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23919
Score = 48.9 bits (115), Expect = 7e-06
Identities = 52/211 (24%), Positives = 76/211 (36%), Gaps = 22/211 (10%)
Query: 145 RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ--KADTKSGLWFTVLEHYHRT 202
+PGPP + +VD S TL W P G + +LGY V+ KAD + T T
Sbjct: 17614 KPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVT 17673
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+S L Y RV A N+ GL E + + D EAP+
Sbjct: 17674 RFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTV---------------KPEDKLEAPE 17718
Query: 263 F---TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
++ G + ++ + P P+I W + + + K + + L
Sbjct: 17719 LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLS 17776
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I D G Y K N G S V V
Sbjct: 17777 IDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17807
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/221 (25%), Positives = 87/221 (39%), Gaps = 22/221 (9%)
Query: 140 ILVIERPGPPQS---IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
IL ++ GPP S + + + TL+W P+ G + + GY ++K + V
Sbjct: 8981 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 9040
Query: 197 EHY-HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR 255
+ TS +V +L Y FRV A N+ G SE + + + K + +
Sbjct: 9041 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG 9100
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
D + K +P+ VTG P PKI W KN+ I+ +T +
Sbjct: 9101 DTIKV-KAGEPVHIPADVTGL-----------PMPKIEWSKNETVIEKPTDALQITKEEV 9148
Query: 316 ------CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I K D G YT A N LG + V+V
Sbjct: 9149 SRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9189
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 123 YQLRV-------QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNT 175
YQ R+ Q LE+ + + PGPP + + S ++W P + G +
Sbjct: 17088 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 17147
Query: 176 ALLGYTVQKADTKSGLWFTVLEH-YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
++GY +++ + S LW V + H T +L G Y FRV+AEN G+ + +
Sbjct: 17148 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKAS 17204
Score = 47.8 bits (112), Expect = 2e-05
Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTSC 204
PGPP ++ D+ + TL W P D G + + GY V++ D + W + T+
Sbjct: 7578 PGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTY 7637
Query: 205 IVSDLIIGNSYAFRVFAENQCG 226
V L Y FRV AEN G
Sbjct: 7638 RVKGLTNKKKYRFRVLAENLAG 7659
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 18/119 (15%)
Query: 123 YQLRVQLG---GLEATATIDILVIER----PGPPQSIKLVDVWGFSATLEWTPPQDTGNT 175
YQ RV+ G+ I+V + PGPP + +V +L W P G +
Sbjct: 21422 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 21481
Query: 176 ALLGYTVQKADTKSGLWFTVLEHYHRTSCI------VSDLIIGNSYAFRVFAENQCGLS 228
+ G+ V+K + S LW V TS I + L+ G Y FRV+AEN GLS
Sbjct: 21482 EVTGFHVEKKERNSILWQKV-----NTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21535
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 37/89 (41%)
Query: 255 RDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
++ S+AP F G N C + P P+I W KN + I +
Sbjct: 26823 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN 26882
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEAS 343
+ SLEIR D G YT KA N G+ S
Sbjct: 26883 VYSLEIRNASVSDSGKYTIKAKNFRGQCS 26911
Score = 47.4 bits (111), Expect = 2e-05
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 3/89 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH--YHRTS 203
P P + +V SA + W P D G + Y ++K +T S W V + + T
Sbjct: 10707 PDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTK 10765
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAP 232
V DL+ G Y FRV AEN+ G+ + +P
Sbjct: 10766 FRVPDLLEGCQYEFRVSAENEIGIGDPSP 10794
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRT 202
++PG P ++ V T+ W PP+ G ++ GY ++K + S W V +
Sbjct: 12089 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPER 12148
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSE 229
V +L+ + Y FRV AEN+ G+ E
Sbjct: 12149 RMKVQNLLPDHEYQFRVKAENEIGIGE 12175
Score = 47.0 bits (110), Expect = 3e-05
Identities = 50/215 (23%), Positives = 76/215 (35%), Gaps = 30/215 (13%)
Query: 145 RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW--FTVLEHYHRT 202
+PGPP + +++D S ++ W P G + + GY V+ A + W T T
Sbjct: 15450 KPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT 15509
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
S ++ L Y R++A N GL E A V T R +
Sbjct: 15510 SYTITGLTENQEYKIRIYAMNSEGLGE-------------PALVPGTPKAEDRMLPPEIE 15556
Query: 263 FTQPLADCTTVTGYNT-QLFCCVRASPRPKIIWLK------NKMDIQGNPKYRALTHLGI 315
L T+ T +LF ++ P P++ W + +K I+ Y L
Sbjct: 15557 LDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI---- 15612
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ FD G Y N G S V V
Sbjct: 15613 ----VGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15643
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
PGPP ++ +VDV L+W PP++ G + Y ++K + W + +
Sbjct: 7879 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7938
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
V+D+I G F+V AEN+ G+ + T L+
Sbjct: 7939 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILS 7972
Score = 46.2 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 73/206 (35%), Gaps = 15/206 (7%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF---TVLEHYHRTSC 204
PP +++DV + +L W P+ G + ++GY V+ W T +
Sbjct: 12887 PPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 12946
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
+ L Y FR A +S + + + T+ + D S A K
Sbjct: 12947 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPV-------TILAENVPPRIDLSVAMKSL 12999
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
T G N L V P P + W K+ ++ + +C+LE+
Sbjct: 13000 -----LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVN 13054
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDV 350
D G YT A N G S ++ V
Sbjct: 13055 RKDSGDYTITAENSSGSKSATIKLKV 13080
Score = 46.2 bits (108), Expect = 4e-05
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
P P++ ++ V S + W P G + +LGY ++K D + W +
Sbjct: 16432 PDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRL 16491
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAP 232
V+ LI + Y FRV AEN GLSE +P
Sbjct: 16492 RVTGLIENHDYEFRVSAENAAGLSEPSP 16519
Score = 45.8 bits (107), Expect = 6e-05
Identities = 27/95 (28%), Positives = 43/95 (45%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P+ Q L T +G + + P+PKI W K + + K + L +L
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ + P D +YTC+A N G A+ + V+VP
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP 3285
Score = 45.8 bits (107), Expect = 6e-05
Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 13/121 (10%)
Query: 120 SGRYQLRVQLG---GLEATATIDILVIERP----GPPQSIKLVDVWGFSATLEWTPPQDT 172
+G+Y+ RV+ G+ D +VI+ P GPP K++ S + WTPP D
Sbjct: 9261 NGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDN 9320
Query: 173 GNTALLGYTVQKADTKSGLWFTVLE------HYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
G + + GY ++K + S W V V L+ G Y FR A N G
Sbjct: 9321 GGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAG 9380
Query: 227 L 227
+
Sbjct: 9381 I 9381
Score = 45.8 bits (107), Expect = 6e-05
Identities = 48/207 (23%), Positives = 76/207 (36%), Gaps = 18/207 (8%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS 203
+ PGP +K+ V S ++ W P G + ++GY V T+ W V++
Sbjct: 13577 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL-SLQ 13634
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
DL G Y FRV AEN+ G + IT +A A KG
Sbjct: 13635 YSAKDLTEGKEYTFRVSAENENGEGTPSEITV-VARDDVVAPDLDLKGL----------- 13682
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
P N +L ++ P P + W K + + + + + +L +
Sbjct: 13683 --PDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDC 13740
Query: 324 GPFDGGIYTCKAVNPLG--EASVDCRV 348
D G YT N G E ++ +V
Sbjct: 13741 QKSDAGKYTITLKNVAGTKEGTISIKV 13767
Score = 45.4 bits (106), Expect = 8e-05
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY--HRTS 203
P PP + V ++WT P+ G + Y V K + KS W V + Y + T
Sbjct: 22935 PSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTR 22994
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSE 229
V+ L+ G Y FRV A N G SE
Sbjct: 22995 LKVTSLMEGCDYQFRVTAVNAAGNSE 23020
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 5/171 (2%)
Query: 61 QTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRR---VSVRNGEQDSILFIREAQR 117
Q+ + G T G P P+ W DG + T V + + + L I +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERPGPPQSI-KLVDVWGFSATLEWTPPQDTG-NT 175
A+SGRY L+ G +AT+T ++LV PP + +L + + + TG T
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT 132
Query: 176 ALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
++ + A+ +S L F + + S ++++ +S + V A N G
Sbjct: 133 PVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/94 (28%), Positives = 41/94 (43%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AP + + G+ + C ++++P + W K +I + K + I SLE
Sbjct: 4528 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4587
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
I + D G YTCKA N G S + V VP
Sbjct: 4588 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4621
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 9/106 (8%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
LE+ + + P PP++ ++ + S + W P G + ++ Y V++ D
Sbjct: 15336 LESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQR 15395
Query: 192 WF-----TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAP 232
W T+ + ++ VS L G+ Y FR+ AEN G+S +P
Sbjct: 15396 WIKCNKKTLTDLRYK----VSGLTEGHEYEFRIMAENAAGISAPSP 15437
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/152 (26%), Positives = 62/152 (40%), Gaps = 18/152 (11%)
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
S I+ +S + V A+N+ G S + I T A ++ K P
Sbjct: 1468 SLIIVPATPSDSGEWTVVAQNRAGRSSISVILT------VEAVEHQVK----------PM 1511
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN--PKYRALTHLGICSLEI 320
F + L + G ++ +P P I+WLKN I + PK R G +L+I
Sbjct: 1512 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKI 1571
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
D YT A+N G + C+V+V+V
Sbjct: 1572 DSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
P P + DV S ++W P+D G+ +LGY ++K + S W V + +
Sbjct: 8598 PDAPDKPIVEDVTSNSMLVKWNEPKDNGSP-ILGYWLEKREVNSTHWSRVNKSLLNALKA 8656
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAP 232
V L+ G +Y FRV AEN G + +P
Sbjct: 8657 NVDGLLEGLTYVFRVCAENAAGPGKFSP 8684
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 133 EATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
E++A + PGPP + K+V + + W P + G + ++GY ++ + S LW
Sbjct: 19269 ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILW 19328
Query: 193 FTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ T VS L G Y +RV+AEN G+ +
Sbjct: 19329 SKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGK 19366
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/208 (22%), Positives = 81/208 (38%), Gaps = 22/208 (10%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP ++ ++ S +L+W+ P G + GY V++ + G W + T V
Sbjct: 19382 PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEV 19441
Query: 207 SDLIIGNSYAFRVFAENQC-GLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
++L Y FRVFA N +SE + T + +D E P+
Sbjct: 19442 TELTEDQRYEFRVFARNAADSVSEPSESTGPI---------------IVKDDVEPPRVMM 19486
Query: 266 PL--ADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ D V G ++ + P P I W K+ ++I+ + ++ L ++
Sbjct: 19487 DVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKD 19546
Query: 323 PGPFDGGIYTCKAVNPLGEAS--VDCRV 348
D G Y N G S V+C+V
Sbjct: 19547 CIRRDTGQYVLTLKNVAGTRSVAVNCKV 19574
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PG P + V S T+ W P+ G + + GY ++ DT S W V + +
Sbjct: 10012 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 10071
Query: 206 -----VSDLIIGNSYAFRVFAENQCGL 227
V+ LI G+ Y FRV+A N G+
Sbjct: 10072 GVSYKVTGLIEGSDYQFRVYAINAAGV 10098
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/216 (25%), Positives = 80/216 (37%), Gaps = 30/216 (13%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRT 202
I PGPP ++ D + LEW PP G ++GY V K + W E +
Sbjct: 8695 ISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKV 8753
Query: 203 -SCIVSDLIIGNSYAFRVFAENQCG---LSETAPITTDLAHIQKAATV---YKTKGFAQR 255
V ++ G Y RV A N G ET P+T +A Q+ V KG Q
Sbjct: 8754 RQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVT--VAEPQEPPAVELDVSVKGGIQ- 8810
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
+ G ++ V P P +W K + ++ + + ++G
Sbjct: 8811 ----------------IMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRV--VIDNVGT 8852
Query: 316 CS-LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
S L I+ D G Y A N G RV+V
Sbjct: 8853 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8888
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 248 KTKGFAQRDFS--EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNP 305
K + +Q+ F+ AP+ T + G NT+ V++ P ++ W N +++Q +
Sbjct: 26054 KYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS 26113
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
K G+ +LEI D G Y N GEAS +DV
Sbjct: 26114 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L++ A I + PGPP + + + ++W P + G T ++GY +++ + S L
Sbjct: 18186 LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 18245
Query: 192 WFTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
W + + T + L G Y F+V AEN G+ + + ++
Sbjct: 18246 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVS 18289
Score = 42.7 bits (99), Expect = 5e-04
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL++ + + P P +VDV S +L WT P+ TG + + GY ++ + S
Sbjct: 13856 GLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSL 13915
Query: 191 LWFTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSE 229
LW + R V+ L G Y FRV A N G+ +
Sbjct: 13916 LWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGK 13955
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)
Query: 248 KTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ---GN 304
K + R P+FT PL + T G N + + P P + W K+ I+ +
Sbjct: 25372 KRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDND 25431
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
KY + G+ L I D YT A N GE S ++ V
Sbjct: 25432 KKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR-TSC 204
P P++ ++ V + W P G + ++GY +++ + S LW + R T
Sbjct: 12787 PSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEY 12846
Query: 205 IVSDLIIGNSYAFRVFAENQCGLS 228
+ L+ G Y+FR++A N+ G S
Sbjct: 12847 PCAGLVEGLEYSFRIYALNKAGSS 12870
Score = 41.6 bits (96), Expect = 0.001
Identities = 49/211 (23%), Positives = 75/211 (35%), Gaps = 26/211 (12%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL--EHYHRTS 203
PGPP + K+ D S +L W+ P G + GY V+ + + W T
Sbjct: 18698 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 18757
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V+ L Y FR+ A N G+ E A + + ++ E P+
Sbjct: 18758 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERI---------------EPPEI 18802
Query: 264 TQPLADCTTV----TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AD V +LF ++ P P++ W K + + + + L
Sbjct: 18803 ELD-ADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLV 18859
Query: 320 IRKPGPFDGGIYTCKAVNPLGE--ASVDCRV 348
I FD G Y N G A V+ RV
Sbjct: 18860 IDNVTRFDSGRYNLTLENNSGSKTAFVNVRV 18890
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 13/100 (13%)
Query: 141 LVIERPG-PPQSIKLVDVWGFSA---TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
++ E P PP + +V+ SA ++ W P G + ++GY V+K + + LW
Sbjct: 22527 IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWV--- 22583
Query: 197 EHYHRTSCI-----VSDLIIGNSYAFRVFAENQCGLSETA 231
++ C+ V+ L+ G Y FR +A N G+S+ +
Sbjct: 22584 -KENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22622
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 236 DLAHIQKAATVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIW 294
D +Q A +KT A E P +FT+PL D T G L C V + K+ W
Sbjct: 5956 DAGEVQLTAKDFKTH--ANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKW 6012
Query: 295 LKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
KN +I + KY + + L I P D YTC A + C ++V P+
Sbjct: 6013 FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA----KDFKTSCNLNVVPPH 6068
Score = 39.7 bits (91), Expect = 0.004
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L + T+ + PGPP + + S ++W P G + ++GY +++ + S L
Sbjct: 16022 LNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSIL 16081
Query: 192 WFTVLEH-YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
W + + +T + L G Y FRV AEN G+ + + ++
Sbjct: 16082 WVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 16125
Score = 39.7 bits (91), Expect = 0.004
Identities = 55/295 (18%), Positives = 110/295 (37%), Gaps = 32/295 (10%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQLR 126
G V G+P P+ W + + + VS+ L IR A +DSG+Y ++
Sbjct: 26843 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 26902
Query: 127 VQ--LGGLEATATIDIL-VIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLG---- 179
+ G ATA++ +L ++E P ++ +G+T+L G
Sbjct: 26903 AKNFRGQCSATASLMVLPLVEEPSREVVLR-----------------TSGDTSLQGSFSS 26945
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPI-TTDLA 238
+VQ + +K F+ +S ++ + E+ +S ++ + +++
Sbjct: 26946 QSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT 27005
Query: 239 HIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWL--K 296
++ + + G PK +D + G + C P P++ W
Sbjct: 27006 QLESSTSKMLKAGIR----GIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 27061
Query: 297 NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
K+ Q ++ + +L I DGG+YT N G S + ++
Sbjct: 27062 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 27116
Score = 39.3 bits (90), Expect = 0.005
Identities = 59/346 (17%), Positives = 123/346 (35%), Gaps = 52/346 (15%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLI 75
K+ E +D + +++ + P+ PI P I L+ T + +
Sbjct: 26515 KISETKKSDQKTTESTVTRKTEPKAPE---PISSKPVI--VTGLQDTTVSS-DSVAKFAV 26568
Query: 76 PFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQ--LGGL 132
G+P+P AIWT DG A+ + + + L I + +DSG Y V+ G +
Sbjct: 26569 KATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSV 26628
Query: 133 EATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
++ + I I + Q + + + ++ AL ++ ++ KS
Sbjct: 26629 SSSCKLTIKAI-KDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKS--- 26684
Query: 193 FTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGF 252
+ + L E A ++K+A K
Sbjct: 26685 -----------------------------QEKLALKEEASKVLISEEVKKSAATSLEKSI 26715
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYNTQ--------LFCCVRASPRPKIIWLKNKMDIQGN 304
+ ++ + ++ + + ++TQ L + + W+ N +++ +
Sbjct: 26716 VHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNS 26775
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+YR +L I++ D GI TC ++ E V C+ D+
Sbjct: 26776 EEYRYGVSGSDQTLTIKQASHRDEGILTC--ISKTKEGIVKCQYDL 26819
Score = 38.9 bits (89), Expect = 0.007
Identities = 36/148 (24%), Positives = 58/148 (39%), Gaps = 8/148 (5%)
Query: 212 GNSYAFRVF---AENQCGLSETAPIT-TDLAHI----QKAATVYKTKGFAQRDFSEAPKF 263
G+SY + V + +Q + A + T L H Q A + +K A+ EAPK
Sbjct: 3432 GSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGEAPKI 3491
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
L D T G Q C ++ + W I+ + + + + I L I
Sbjct: 3492 FLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLTICNV 3551
Query: 324 GPFDGGIYTCKAVNPLGEASVDCRVDVK 351
D G+Y+C N GE + + V+
Sbjct: 3552 QLVDQGLYSCIVHNDCGERTTSAVLSVE 3579
Score = 38.9 bits (89), Expect = 0.007
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 163 TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFA 221
T+ W PP D G + + GY ++K +T++ W V + + + L G Y FRV A
Sbjct: 13200 TVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTA 13259
Query: 222 ENQCG 226
N+ G
Sbjct: 13260 INKAG 13264
Score = 38.5 bits (88), Expect = 0.009
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 25/162 (15%)
Query: 2 EAATAPEVAAGSKLKVKEA-----SPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLP 56
EA E AA K +K SP +AE + PG G P +E P +
Sbjct: 4753 EAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPP-------DEAPFTYQL 4805
Query: 57 RALRQTYIRKVGDTVNLLIPFQGKP-------KPQAI---WTHDGCAL--DTRRVSVRNG 104
+A+ +++++ D + F G P W DG + + + +G
Sbjct: 4806 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADG 4865
Query: 105 EQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERP 146
+ D L I + Q +D+G Y ++LG E T+T ++V E P
Sbjct: 4866 K-DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP 4906
Score = 38.1 bits (87), Expect = 0.012
Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 3/115 (2%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWT 88
+A+ G G + T +LL E P ++ R T + G V L + G P P +
Sbjct: 81 KATNGSGQATSTAELLVKAETAPPNFVQRLQSMTV--RQGSQVRLQVRVTGIPTPVVKFY 138
Query: 89 HDGCALDTRRVSVRNGEQDSI-LFIREAQRADSGRYQLRVQLGGLEATATIDILV 142
DG + + + E D L I EA DSG Y + AT+T ++LV
Sbjct: 139 RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 37.0 bits (84), Expect = 0.027
Identities = 23/83 (27%), Positives = 37/83 (44%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P F Q L T G +L V P P + + ++ +IQ + ++ + SL I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 321 RKPGPFDGGIYTCKAVNPLGEAS 343
+ P D G Y+ A N +G A+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRAT 186
Score = 36.6 bits (83), Expect = 0.035
Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 22/126 (17%)
Query: 13 SKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKV----- 67
+++ SPA P + SPG+ +EE + L R + ++ K
Sbjct: 1374 ARMSPARMSPARMSPARMSPGRR-----------LEETDESQLERLYKPVFVLKPVSFKC 1422
Query: 68 --GDTVNLLIPFQGKPKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIREAQRADSGR 122
G T + G+P P+ W HDG + T +V ++ S++ + A +DSG
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGE 1481
Query: 123 YQLRVQ 128
+ + Q
Sbjct: 1482 WTVVAQ 1487
Score = 35.4 bits (80), Expect = 0.078
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 258 SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN--PKYRALTHLGI 315
++AP FTQPL + G + P P++ W ++ I + P + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L I + G Y+ KA N G+A+ + VK
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 35.4 bits (80), Expect = 0.078
Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 1/92 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P PL D T G + C V + K+ W I+ + +R LEI
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
+ P D G YT A N +G+ S + ++V
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEV 3389
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA-LTHLGICSLEIR 321
F + + + G C + P PKI W K+ I+ +Y+ G SL I
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 322 KPGPFDGGIYTCKAVNPLGEA 342
P D GIYT A N G A
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNA 1327
Score = 34.7 bits (78), Expect = 0.13
Identities = 18/64 (28%), Positives = 27/64 (42%)
Query: 288 PRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCR 347
P + WL + ++ + R + G CSL+ D GI TC+A N G
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745
Query: 348 VDVK 351
+ VK
Sbjct: 1746 LIVK 1749
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPK-YRALTHLGICS 317
EAPK + + T G + V P P+ W KN + I+ + + Y +C
Sbjct: 2030 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2089
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEAS 343
L IR D KA+N GE S
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETS 2115
Score = 33.9 bits (76), Expect = 0.23
Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL-GICSLE 319
P F + L G V P P + W K + + Y + + G +
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826
Query: 320 IRKPGPFDGGIYTCKAVNPLGEAS 343
+ P D G+Y CKA N LGE++
Sbjct: 3827 VNDPQREDSGLYICKAENMLGEST 3850
Score = 33.9 bits (76), Expect = 0.23
Identities = 64/278 (23%), Positives = 101/278 (36%), Gaps = 41/278 (14%)
Query: 69 DTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRV 127
DT+ L+ KP + IW D ++T R + + IL I+ A D+G Y R+
Sbjct: 6173 DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRL 6231
Query: 128 QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ-KAD 186
+ + L E PQ++++ LE + + + + VQ K D
Sbjct: 6232 PSSRTDGKVKVHELAAEFISKPQNLEI---------LEGEKAEFVCSISKESFPVQWKRD 6282
Query: 187 TK---SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
K SG + V+ + +V D + + + V G + A AH+
Sbjct: 6283 DKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAA------AHL--- 6329
Query: 244 ATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
TV E + PL D T V +F C + K W +N+ I
Sbjct: 6330 -TVI-----------EKLRIVVPLKD-TRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFD 6376
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
+ KY L + +L IR D Y N GE
Sbjct: 6377 SSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGE 6414
Score = 33.5 bits (75), Expect = 0.30
Identities = 17/61 (27%), Positives = 26/61 (42%)
Query: 291 KIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
++ W ++ + KY G+ L ++ D G Y CK VN GE S + V
Sbjct: 25294 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25353
Query: 351 K 351
K
Sbjct: 25354 K 25354
Score = 33.1 bits (74), Expect = 0.39
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 260 APKF-TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL--THLGIC 316
AP F T+P+ V G + C V +P+P + W K+ + + +Y+ G C
Sbjct: 1035 APYFITKPVVQ-KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGEC 1093
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEAS 343
L I D G YT N GE S
Sbjct: 1094 KLVISMTFADDAGEYTIVVRNKHGETS 1120
Score = 32.7 bits (73), Expect = 0.51
Identities = 21/74 (28%), Positives = 29/74 (39%)
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
FTQ L D F C + P K+ W K+ M++ KYR + + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILT 2189
Query: 323 PGPFDGGIYTCKAV 336
D Y+C V
Sbjct: 2190 IDTSDAEDYSCVLV 2203
Score = 32.3 bits (72), Expect = 0.66
Identities = 32/105 (30%), Positives = 42/105 (40%), Gaps = 7/105 (6%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQD 107
E PKI+L Q K GDT L + WTH+G + ++ R+
Sbjct: 3487 EAPKIFLHL---QDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNI 3543
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSI 152
L I Q D G Y V E T T +L +E G P+SI
Sbjct: 3544 QFLTICNVQLVDQGLYSCIVHNDCGERT-TSAVLSVE--GAPESI 3585
Score = 32.0 bits (71), Expect = 0.86
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
Query: 246 VYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNP 305
VY TK ++++ P F + +++ G L V P+PKI W N + + +
Sbjct: 3635 VYPTKFDSEKE-GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSA 3693
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
Y+ + SL I D G YTC A N G+
Sbjct: 3694 DYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGK 3729
Score = 31.2 bits (69), Expect = 1.5
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 245 TVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
T + K A+ EAP +F + L D TVT ++ +F C + + + W +N +I+
Sbjct: 6501 TAGQDKSVAELLIIEAPTEFVEHLED-QTVTEFDDAVFSCQLSREKANVKWYRNGREIKE 6559
Query: 304 NPKYR 308
KY+
Sbjct: 6560 GKKYK 6564
Score = 30.8 bits (68), Expect = 1.9
Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 12/114 (10%)
Query: 79 GKPKPQAIWTHDGCALDTR--RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATA 136
G+P P W + L T + N + + QR DSG Y + + E+T
Sbjct: 3792 GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTC 3851
Query: 137 TIDILVIERPGPPQSIKLVDVWGFSATLEWTP--PQDTGNTALLGYTVQKADTK 188
++LV+ ++ D+ + TP P+D T L G V+ D++
Sbjct: 3852 AAELLVL--------LEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSE 3897
Score = 30.0 bits (66), Expect = 3.3
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 275 GYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCK 334
G + C V P+PK+ W N I+ + ++R + + GI L+I +D G
Sbjct: 1809 GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFR-VRYDGIHYLDIVDCKSYDTGEVKVT 1867
Query: 335 AVNPLGEASVDCRVDVK 351
A NP G +++++
Sbjct: 1868 AENPEGVIEHKVKLEIQ 1884
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPK-IIWLKNKMDIQGNPKYRALTHLGICS 317
EA K + L + T VT +F P K + W+KN + ++ N KY I S
Sbjct: 2659 EAVKIKKTLKNLT-VTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYS 2717
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L I+ D +Y + LG R+ V+
Sbjct: 2718 LRIKNCAIVDESVYGFR----LGRLGASARLHVE 2747
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 113 bits (283), Expect = 2e-25
Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 5/177 (2%)
Query: 62 TYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADS 120
+Y +VG + + +P G+PKP WT DG L T R++V + + L I+E + D
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 16925
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLG 179
G+Y + V + TA+I+I+ +++P PP+ +K DV S TL W PP TG +
Sbjct: 16926 GQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITN 16985
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETAPI 233
Y VQK DT + +W V RT+ V+ L G Y FR+FAEN+ G S E+ PI
Sbjct: 16986 YIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI 17042
Score = 112 bits (280), Expect = 5e-25
Identities = 67/189 (35%), Positives = 100/189 (52%), Gaps = 4/189 (2%)
Query: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRV 99
P + IE P + LP T+ K + + + +PF+G+P+ W DG L +T RV
Sbjct: 19013 PVIARDIEIKPSVELPF---HTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRV 19069
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWG 159
+V + + + L I+EA + D G Y+L V T I I+V++RPGPP I++ +V
Sbjct: 19070 NVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSC 19129
Query: 160 FSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRV 219
S T+ W PP+ G + Y V+K +T S W V + RTS + L G+ Y FRV
Sbjct: 19130 DSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRV 19189
Query: 220 FAENQCGLS 228
AEN+ G S
Sbjct: 19190 CAENRYGKS 19198
Score = 110 bits (275), Expect = 2e-24
Identities = 67/212 (31%), Positives = 105/212 (49%), Gaps = 8/212 (3%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLI 75
+VK + A P + S PQ+ EE P + +R+T I K G + + +
Sbjct: 19784 RVKSVNKVGASDP-------SDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTV 19836
Query: 76 PFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEAT 135
PF+G+P P +W+ L TR V + + L I A R DSG+Y L +Q A+
Sbjct: 19837 PFRGRPVPNVLWSKPDTDLRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAAS 19895
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
T+ + V++ PGPP +I + DV SA L W P++ G + Y ++K + W +V
Sbjct: 19896 LTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSV 19955
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
+ +R S V++L G Y FRV EN+ G+
Sbjct: 19956 TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19987
Score = 108 bits (270), Expect = 7e-24
Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 6/185 (3%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD-GCALDTRRVSVRNGEQDSI 109
P+I L LR+ + T+ L +P +G+P P+ W D G +LD + S+ + ++
Sbjct: 15486 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIESTSSYTL 15543
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPP 169
L + R DSG+Y L V+ +A +++ V++ PGPPQ +K+ +V S TL W PP
Sbjct: 15544 LIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPP 15603
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL-- 227
G + + Y V+K ++ + TV + H+TS V L G SY FRV AEN+ G+
Sbjct: 15604 LLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGL 15663
Query: 228 -SETA 231
+ETA
Sbjct: 15664 PAETA 15668
Score = 108 bits (270), Expect = 7e-24
Identities = 68/206 (33%), Positives = 102/206 (49%), Gaps = 6/206 (2%)
Query: 35 GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G G P P I E P+I L ALR + I K G+ V +LIPF+G+P P W D
Sbjct: 20877 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKD 20936
Query: 91 GCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG-GLEATATIDILVIERPGP 148
L + R S+ N + S+L I + R D+G+Y L ++ G G ++T+ + V++ P
Sbjct: 20937 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAA 20996
Query: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
Q +++ V + TL W PP G + ++ Y ++K D W V TS + D
Sbjct: 20997 CQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLID 21056
Query: 209 LIIGNSYAFRVFAENQCGLSETAPIT 234
L + FRV AEN+ G+ E T
Sbjct: 21057 LSEKTPFFFRVLAENEIGIGEPCETT 21082
Score = 107 bits (266), Expect = 2e-23
Identities = 75/252 (29%), Positives = 122/252 (48%), Gaps = 14/252 (5%)
Query: 57 RALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREA 115
+ L T+ G+ + + +PF G+P P W D L T RV+ + E +S+L I++A
Sbjct: 15779 KLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDA 15838
Query: 116 QRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGN 174
R D G Y +++ EA T++++V+++PGPP +K+ +V S TL W PP+ G
Sbjct: 15839 CREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGG 15898
Query: 175 TALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETA 231
+++ Y V+K DT + W V RT+ L G Y FR+ AEN+ G S +
Sbjct: 15899 SSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE 15958
Query: 232 PITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLAD-CTTVTGYNTQLFCCVRASPRP 290
P + RD E ++ +P++D + V GY+ + R
Sbjct: 15959 PTVAQYPFKVPGPPGTPVVTLSSRDSMEV-QWNEPISDGGSRVIGYH------LERKERN 16011
Query: 291 KIIWLK-NKMDI 301
I+W+K NK I
Sbjct: 16012 SILWVKLNKTPI 16023
Score = 106 bits (265), Expect = 3e-23
Identities = 62/192 (32%), Positives = 102/192 (53%), Gaps = 6/192 (3%)
Query: 39 PTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR- 97
P L+PP E L LR+T I + G T+ L +P +G+P P+ W+ L R
Sbjct: 13312 PKDILIPPEGE-----LDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRI 13366
Query: 98 RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDV 157
+ +++ + D+ L + D+G+Y L ++ + TI + V++ PGPP ++ + ++
Sbjct: 13367 GLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEI 13426
Query: 158 WGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAF 217
SA + W PP G + ++ Y VQK D + W TV +TS V++L G SY F
Sbjct: 13427 SKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFF 13486
Query: 218 RVFAENQCGLSE 229
RVFAEN+ G+ +
Sbjct: 13487 RVFAENEYGIGD 13498
Score = 105 bits (263), Expect = 5e-23
Identities = 62/203 (30%), Positives = 100/203 (49%), Gaps = 7/203 (3%)
Query: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRV 99
P + + P + LP TY + G+ + + IP G+P+P W DG L T RV
Sbjct: 17930 PVIAKDLTIQPSLKLPF---NTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRV 17986
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVW 158
+V ++L I+E + D G+Y + AT + ++V+E+PGPP ++ +V
Sbjct: 17987 NVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVS 18046
Query: 159 GFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFR 218
+ W PP TG + Y V+K DT + W V RT+ ++ L G Y FR
Sbjct: 18047 ADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFR 18106
Query: 219 VFAENQCGLSETAPITTDLAHIQ 241
+FAEN+ G ++AP+ + +Q
Sbjct: 18107 IFAENRYG--KSAPLDSKAVIVQ 18127
Score = 104 bits (259), Expect = 1e-22
Identities = 71/226 (31%), Positives = 104/226 (46%), Gaps = 13/226 (5%)
Query: 12 GSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTV 71
G K K + A+ +G QLLPP KI +P + K G +
Sbjct: 12494 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPP-----KILMPEQITI----KAGKKL 12544
Query: 72 NLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG 130
+ GKP P W + + + ++V + SIL I++ R DSG Y L +
Sbjct: 12545 RIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 12604
Query: 131 GLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKS 189
T I ++V++ PGPPQ + D+ + +L W P + G + + Y V+K D
Sbjct: 12605 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSR 12664
Query: 190 GLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITT 235
G W T L +TSC V LI G Y FRV AEN+ G+SE P+T+
Sbjct: 12665 GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE--PLTS 12708
Score = 103 bits (257), Expect = 2e-22
Identities = 60/191 (31%), Positives = 97/191 (50%), Gaps = 4/191 (2%)
Query: 48 EEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQ 106
+E P+I+L L K G + L GKP+P+ WT L +R+++ N +
Sbjct: 7313 QEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK 7372
Query: 107 DSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEW 166
S + I +++R+D+G Y + ATA +++ V+++PGPP + + DV S L W
Sbjct: 7373 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7432
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
PP+D G + + Y V++ T S +W + T+ + LI Y FRV AEN G
Sbjct: 7433 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 7492
Query: 227 LSE---TAPIT 234
+ E +PIT
Sbjct: 7493 VGEPVQASPIT 7503
Score = 102 bits (255), Expect = 4e-22
Identities = 57/204 (27%), Positives = 101/204 (49%), Gaps = 6/204 (2%)
Query: 36 AGSPTPQLLPPIE-----EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
AG P ++P +E P L LR+T + + G ++ + +P +G+P P+ WT D
Sbjct: 14382 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14441
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
L R ++ N E ++L I E R D+G++ + ++ + + +++ V++ PGP
Sbjct: 14442 NINLKNR-ANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14500
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
+++ D+ S TL W P G + + Y V+K + + T H+ + V+ L
Sbjct: 14501 NLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLS 14560
Query: 211 IGNSYAFRVFAENQCGLSETAPIT 234
G Y FRV AEN+ G+ E T
Sbjct: 14561 EGCEYFFRVMAENEYGIGEPTETT 14584
Score = 102 bits (253), Expect = 7e-22
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 2/190 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDT-RRVSVRNGEQDSI 109
P + L L + + K G TV +G P P A WT DG + T +V S+
Sbjct: 11136 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11195
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L I+ R D+G YQ+ V T + + V++ PGPP I ++DV T+ W P
Sbjct: 11196 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP 11255
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P+D G + ++ Y V+K DT+ W V +T + L G Y FRV AEN+ G+
Sbjct: 11256 PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVG 11315
Query: 229 ETAPITTDLA 238
T +A
Sbjct: 11316 PPLDSTPTVA 11325
Score = 101 bits (252), Expect = 9e-22
Identities = 61/176 (34%), Positives = 93/176 (52%), Gaps = 10/176 (5%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCALD---TRRVSVRNGEQDSILFIREAQRADSGR 122
K GDT+ L +GKP P+ WT D A D + RV + S + +A+R+D G+
Sbjct: 11842 KAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGK 11901
Query: 123 YQLRVQ--LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY 180
Y + G A AT+++L ++PGP +++K+VDV T+ W PP+D G + Y
Sbjct: 11902 YVVTATNTAGSFVAYATVNVL--DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNY 11959
Query: 181 TVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL---SETAPI 233
++K +TK +W T V+ LI GN Y FRV AEN+ G +E+ P+
Sbjct: 11960 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPV 12015
Score = 101 bits (252), Expect = 9e-22
Identities = 61/199 (30%), Positives = 96/199 (48%), Gaps = 2/199 (1%)
Query: 32 PGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDG 91
PG+ A P + + E+P L ++ + G + L IP +GKP P WT +G
Sbjct: 23743 PGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG 23802
Query: 92 CALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS 151
+ ++R + E + L I+EA R DSG Y L ++ + I + VI P P+
Sbjct: 23803 QDI-SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEG 23861
Query: 152 -IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
++ D+ S + W PP D G +LGY +++ + W+T+ TS +V L
Sbjct: 23862 PLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLK 23921
Query: 211 IGNSYAFRVFAENQCGLSE 229
Y FRV AENQ G+S+
Sbjct: 23922 ENVEYHFRVSAENQFGISK 23940
Score = 101 bits (251), Expect = 1e-21
Identities = 86/307 (28%), Positives = 134/307 (43%), Gaps = 30/307 (9%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRR-VSVRNGEQDSI 109
P I LP + + G +V L GKP P W D L T V V N +
Sbjct: 20498 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20557
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
+ I++A R +SG Y+L+++ A+ATI + ++++PGPP I+ V TL W P
Sbjct: 20558 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRP 20617
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P D G + Y V+K +T +W V EH + +I GN Y FRV A N+ G+
Sbjct: 20618 PADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIG 20677
Query: 229 ETAPITTDLAHIQKAATVYKTKGFAQ----RDFSEAPKFTQPLAD-CTTVTGY------- 276
E P+ +D + A G + S +++P+AD + ++GY
Sbjct: 20678 E--PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDK 20735
Query: 277 -NTQLFCCVRAS---PRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYT 332
+ F ++ + R K+ L D Q YR +C++ GPF
Sbjct: 20736 KSLGWFKVLKETIRDTRQKVTGLTENSDYQ----YR------VCAVNAAGQGPFSEPSEF 20785
Query: 333 CKAVNPL 339
KA +P+
Sbjct: 20786 YKAADPI 20792
Score = 100 bits (248), Expect = 3e-21
Identities = 58/170 (34%), Positives = 89/170 (52%), Gaps = 4/170 (2%)
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWT--HDGCALDTRRVSVRNGEQDSILFIREAQRADS 120
Y+ K L IP +GKP P W D A DTR VSV + ++ L + + Q++D+
Sbjct: 13620 YLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTR-VSVESSAVNTTLIVYDCQKSDA 13678
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLG 179
G+Y + ++ TI I V+ +PG P IK +V + TL+W PP+D G + +
Sbjct: 13679 GKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITN 13738
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
Y ++K D+ + W T +T+ V+ L G Y FRV AEN+ G+ E
Sbjct: 13739 YILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13788
Score = 99.8 bits (247), Expect = 3e-21
Identities = 55/166 (33%), Positives = 83/166 (50%), Gaps = 1/166 (0%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQL 125
V + + +L+P G P+P A W L+T RV ++ + L I ++R+D G Y L
Sbjct: 7036 VPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTL 7095
Query: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
+++ + ID+ VI RP P+ +K D+ S L W PP D G + L GY V+K
Sbjct: 7096 KLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR 7155
Query: 186 DTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
+ W V++ V DL+ G Y F+V A N+CG E A
Sbjct: 7156 EVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201
Score = 99.8 bits (247), Expect = 3e-21
Identities = 62/201 (30%), Positives = 99/201 (49%), Gaps = 6/201 (2%)
Query: 35 GAGSPTPQLLPPIE----EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G P LLP + E P+I + T + G + + IP GKP P+ + D
Sbjct: 20082 GLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRD 20141
Query: 91 GCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
G L T R + ++ + ++E+ AD+GRY++ A I+I+V++RPGPP
Sbjct: 20142 GVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPP 20201
Query: 150 QS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
+ + D+ S TL+W PP+ G + + Y + K +T + +W V RT V
Sbjct: 20202 TGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMK 20261
Query: 209 LIIGNSYAFRVFAENQCGLSE 229
L G Y FR+ AEN+ G+S+
Sbjct: 20262 LTTGEEYQFRIKAENRFGISD 20282
Score = 99.4 bits (246), Expect = 4e-21
Identities = 61/234 (26%), Positives = 106/234 (45%), Gaps = 19/234 (8%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNL 73
+ +VK + A P + G+ + I+E P++++ + + K G + +
Sbjct: 9406 RFRVKAVNEAGESEPSDTTGEIPATD-------IQEEPEVFIDIGAQDCLVCKAGSQIRI 9458
Query: 74 LIPFQGKPKPQAIWTHDGCALDTRRVSVRN---------GEQDSILFIREAQRADSGRYQ 124
+G+P P++ W DG A + V + E S++ I E +R+ +G+Y
Sbjct: 9459 PAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYS 9518
Query: 125 LRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK 184
+ + + TA + V++ PGPP+ +K+ D+ S L W P D G + GY ++K
Sbjct: 9519 ITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEK 9578
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETAPITT 235
W V T+ +V DL+ Y FRV AEN+ G+ ET TT
Sbjct: 9579 RTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTT 9632
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/190 (32%), Positives = 92/190 (48%), Gaps = 5/190 (2%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSI- 109
P+I L A++ K G V L GKP P W DG L ++ Q ++
Sbjct: 12921 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE-GIKMAMQRNLC 12979
Query: 110 -LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTP 168
L + R DSG Y + + +ATI + V+++PGPP S+K+ ++ A L W P
Sbjct: 12980 TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEP 13039
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P + G + + Y V K +T W V TSC V LI G+ Y FR+ AEN+ G+
Sbjct: 13040 PLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVG 13099
Query: 229 ETAPITTDLA 238
+ P+ T+ A
Sbjct: 13100 D--PVFTEPA 13107
Score = 98.6 bits (244), Expect = 8e-21
Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQD 107
E PKI + + T I K G+ L G+P P W+ DG L+ T ++ ++ +
Sbjct: 15085 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS 15144
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEW 166
+ L +++ R DSG Y L G A ++ V++RPGPP+ + + +V L W
Sbjct: 15145 TNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSW 15204
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
PP D G + Y VQK +T W V T V+ L+ GN Y FRV A N+ G
Sbjct: 15205 FPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYG 15264
Query: 227 LSE 229
+ E
Sbjct: 15265 VGE 15267
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/225 (27%), Positives = 108/225 (48%), Gaps = 12/225 (5%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P+I + + T + G++ + GKP P W L +T R+ +++ + +
Sbjct: 16169 PRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS 16228
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L +++A R DSG Y L+ + E + T+++ V++RPGPP+ + + V TL W P
Sbjct: 16229 LSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKP 16288
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P G + ++ Y V++ +T +W V + SC V+ L+ GN Y FR+ A N+ G+
Sbjct: 16289 PLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 16348
Query: 229 ETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTV 273
E P+ ++ V F D +AP+ T D V
Sbjct: 16349 E--PLESE--------PVVAKNPFVVPDAPKAPEVTTVTKDSMIV 16383
Score = 98.2 bits (243), Expect = 1e-20
Identities = 60/200 (30%), Positives = 97/200 (48%), Gaps = 2/200 (1%)
Query: 29 QASPGQGAGSPTPQLLPPIE--EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAI 86
Q G G + + + P E E P+I L ++R+ I + G + L +G+P P+
Sbjct: 12208 QNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVT 12267
Query: 87 WTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERP 146
W G R+ V + + L I + R DSG+Y L + E +++ V++ P
Sbjct: 12268 WRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTP 12327
Query: 147 GPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIV 206
GP +K+ DV S + W PP++ G + + Y V+K + W TV +TS V
Sbjct: 12328 GPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHV 12387
Query: 207 SDLIIGNSYAFRVFAENQCG 226
++L+ GN Y FRV A N+ G
Sbjct: 12388 TNLVPGNEYYFRVTAVNEYG 12407
Score = 97.8 bits (242), Expect = 1e-20
Identities = 60/205 (29%), Positives = 102/205 (49%), Gaps = 5/205 (2%)
Query: 33 GQGAGSPTPQLLPPIE--EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G G + P + P + E P++ L LR+ + + G + + IPF+G+P P+ W+ +
Sbjct: 17630 GLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSRE 17689
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
T +V + G + L I R D+G+Y L+++ +A + + V++ PGPPQ
Sbjct: 17690 EGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQ 17748
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
++ + +V SA L W PP G + Y + K ++ + V +TS V +L
Sbjct: 17749 NLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLT 17808
Query: 211 IGNSYAFRVFAENQCGLSETAPITT 235
G Y FRV AEN+ G+ P+ T
Sbjct: 17809 EGAIYYFRVMAENEFGVG--VPVET 17831
Score = 97.8 bits (242), Expect = 1e-20
Identities = 56/179 (31%), Positives = 86/179 (48%), Gaps = 1/179 (0%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
P++ + +QT++ + G ++ L I +QG+P P A+W+ L R + + S L
Sbjct: 21983 PELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR-ADIHTTDSFSTL 22041
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQ 170
+ R D+G+Y L V+ + T + V++ PGPP I DV SATL W P
Sbjct: 22042 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPL 22101
Query: 171 DTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
G + Y V+K + W + E R V+DL G Y FRV A N+ G+ E
Sbjct: 22102 LDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGE 22160
Score = 97.4 bits (241), Expect = 2e-20
Identities = 60/179 (33%), Positives = 91/179 (50%), Gaps = 2/179 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P I L ++T G V L+IP G+P P A W G L ++ RV+V + +
Sbjct: 23364 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23423
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L IRE D+G Y L ++ + TI ++++++PGPP IK+ ++ S T+ W P
Sbjct: 23424 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23483
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
P+ G L GY V++ D W V E R++ + L GN Y FRV A N+ G+
Sbjct: 23484 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGI 23542
Score = 96.7 bits (239), Expect = 3e-20
Identities = 55/190 (28%), Positives = 94/190 (49%), Gaps = 5/190 (2%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQD 107
E P+I + R T + G+T L GKP P W ++ + R ++N +
Sbjct: 17249 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17308
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEW 166
++L +++A R D G+Y LR + +++ V++RPGPP+ +++ V +L W
Sbjct: 17309 ALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW 17368
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
+PP G + + Y V+K +T W V S V+ L+ GN Y FR+ A N+ G
Sbjct: 17369 SPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYG 17428
Query: 227 LS---ETAPI 233
+ E+AP+
Sbjct: 17429 VGEPLESAPV 17438
Score = 94.7 bits (234), Expect = 1e-19
Identities = 62/198 (31%), Positives = 92/198 (46%), Gaps = 3/198 (1%)
Query: 30 ASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH 89
A A P P L+ E P++ L + + KVGDT+ L +G P P+ W
Sbjct: 10823 AGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKK 10882
Query: 90 DGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGP 148
+ T+ R+ V S L IR A D G Y L V+ T ++ +LV+++PGP
Sbjct: 10883 EDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGP 10940
Query: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
P+ +++ ++ S L W P D G + + Y V++ D S W + + S
Sbjct: 10941 PRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH 11000
Query: 209 LIIGNSYAFRVFAENQCG 226
L GN Y FRV AENQ G
Sbjct: 11001 LNEGNQYLFRVAAENQYG 11018
Score = 93.6 bits (231), Expect = 2e-19
Identities = 55/190 (28%), Positives = 91/190 (47%), Gaps = 6/190 (3%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD--TRRVSVRNGEQDS 108
P L + + G+T L +GKP P +W+ DG L+ R+ +++ Q +
Sbjct: 18333 PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKT 18392
Query: 109 ILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWT 167
L +++ R D G+Y L++ G + I + V++RPGPP+ +K+ V L W
Sbjct: 18393 TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 18452
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
PP G + Y ++K +T W V + V+ L+ GN Y FRV A N+ G+
Sbjct: 18453 PPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18512
Query: 228 S---ETAPIT 234
E+ P+T
Sbjct: 18513 GEPLESGPVT 18522
Score = 93.6 bits (231), Expect = 2e-19
Identities = 55/187 (29%), Positives = 94/187 (50%), Gaps = 3/187 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQD 107
E P+I L LR+ + + T+ L + +G+P+P+ W +G D ++ V +
Sbjct: 18731 EPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSF-- 18788
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWT 167
++L I R DSGRY L ++ TA +++ V++ P P ++ + +V S TL W
Sbjct: 18789 TMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWE 18848
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
PP G + Y V+K +T + T+ + +T+ + +L G SY FRV A N+ G+
Sbjct: 18849 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908
Query: 228 SETAPIT 234
A T
Sbjct: 18909 GLPAETT 18915
Score = 93.6 bits (231), Expect = 2e-19
Identities = 64/205 (31%), Positives = 100/205 (48%), Gaps = 7/205 (3%)
Query: 45 PPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRN 103
P IE P L Q K G + +P G+P P+ W + L +T RVS+
Sbjct: 22269 PQIE--PTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT 22326
Query: 104 GEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSA 162
+ + L ++++ R DSGRY L ++ T ++ ++VI RPGP I++ V S
Sbjct: 22327 TKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESC 22386
Query: 163 TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAE 222
L W P+D G T + Y V+K ++ + W V RT V+ L Y+FRV +E
Sbjct: 22387 VLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSE 22446
Query: 223 NQCGLS---ETAPITTDLAHIQKAA 244
N+ G+S E+API + + +A
Sbjct: 22447 NRFGVSKPLESAPIIAEHPFVPPSA 22471
Score = 93.2 bits (230), Expect = 3e-19
Identities = 66/236 (27%), Positives = 103/236 (43%), Gaps = 11/236 (4%)
Query: 5 TAPEVAAGS--KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQT 62
T E+ G+ KL+V + A PP G P + +E P + L +++
Sbjct: 8690 TVKEIREGADYKLRVSAVNAAGEGPP--------GETQPVTVAEPQEPPAVELDVSVKGG 8741
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
G T+ + G+P P +WT + LD RV + N S L I++A R D GR
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGR 8801
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Y + A + V + PGP +K V L W+ P+D G + + G+ +
Sbjct: 8802 YVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 8861
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
++ D K W +E R+ C ++ L+ G Y FRV A+N+ G I LA
Sbjct: 8862 ERKDAKMHTWRQPIE-TERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILA 8916
Score = 93.2 bits (230), Expect = 3e-19
Identities = 57/200 (28%), Positives = 98/200 (49%), Gaps = 3/200 (1%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWT 88
+A G+ A P P ++ E P I L LR+ + G ++ L +P +G+P P+ W
Sbjct: 16546 KAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWG 16605
Query: 89 H-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPG 147
DG D + V + +L R DSG+Y L ++ +A + + V++ P
Sbjct: 16606 KVDGEIRDAAIIDVTSSFTSLVL--DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPS 16663
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVS 207
PP ++K+ ++ S ++ W PP G + + Y V+K + + V+ + H+ S +
Sbjct: 16664 PPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKID 16723
Query: 208 DLIIGNSYAFRVFAENQCGL 227
L G SY FRV AEN+ G+
Sbjct: 16724 QLQEGCSYYFRVTAENEYGI 16743
Score = 91.7 bits (226), Expect = 9e-19
Identities = 57/183 (31%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNL-LIPFQGKPKPQAIWTHDGCALDTRRVS-VRNGEQ 106
E P I L ++ K GDT+ L I GKP P++ W+ G + ++ + +
Sbjct: 14002 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 14061
Query: 107 DSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEW 166
S+L I+ A R D+G Y + + + V++ PGPP +++ +V ATL W
Sbjct: 14062 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTW 14121
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
TPP + G + + Y ++K +T LW V E + + LI GN Y FRV A N G
Sbjct: 14122 TPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 14181
Query: 227 LSE 229
E
Sbjct: 14182 KGE 14184
Score = 90.5 bits (223), Expect = 2e-18
Identities = 69/223 (30%), Positives = 96/223 (43%), Gaps = 7/223 (3%)
Query: 12 GSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRA-LRQTY----IRK 66
G + V+ + + Q AG P+ P+ + LP LR Y I K
Sbjct: 14647 GLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAK 14706
Query: 67 VGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
GD + + IP G+PKP W D T+RV+ +IL I E R+DSG Y L
Sbjct: 14707 AGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 14766
Query: 126 RVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK 184
+ E I I V + PGPP IK +V T W PP++ G + Y V+
Sbjct: 14767 TARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEM 14826
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
T S W + RT+ + L G Y FRV A+N+ G+
Sbjct: 14827 RQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGV 14869
Score = 90.1 bits (222), Expect = 3e-18
Identities = 56/191 (29%), Positives = 92/191 (48%), Gaps = 2/191 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P++ L R +VG T+ +L +G+P+P WT +G L +RV +
Sbjct: 11534 PEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE 11593
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPP 169
L I+EA RAD G+Y + + A + + V++RPGP Q++K+ +V + T+ W P
Sbjct: 11594 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENP 11653
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
D G + + + V+ W V + I ++L+ N Y FRV AEN+ G+
Sbjct: 11654 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGVGP 11712
Query: 230 TAPITTDLAHI 240
T T + I
Sbjct: 11713 TIETKTPILAI 11723
Score = 89.7 bits (221), Expect = 3e-18
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 4/173 (2%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGC-ALDTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+VG+ L + GKPKP+ W D L+ R ++ L +A+R+DSG+Y
Sbjct: 10459 RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYC 10518
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ V+ + V++RPGPP + +V + W PP D G + + Y ++
Sbjct: 10519 VVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIE 10578
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTD 236
K + +W V +T+C VS L+ G Y FR+ AEN G+S+ P+ +D
Sbjct: 10579 KKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISD--PLVSD 10629
Score = 89.7 bits (221), Expect = 3e-18
Identities = 61/227 (26%), Positives = 105/227 (46%), Gaps = 10/227 (4%)
Query: 5 TAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIE--EHPKIWLPRALRQT 62
T P++ G K + A+ G S + + P+E E P + L L++T
Sbjct: 23031 TVPDLKMGQKYSFRVAAVN-------VKGMSEYSESIAEIEPVERIEIPDLELADDLKKT 23083
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
+ G ++ L++ G+P P W+ G L +R + + E S+L + + R D+G+
Sbjct: 23084 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIVDKVNRYDAGK 23142
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Y + + + +AT+ + V + PGP S+K+ +V S T+ W P G + Y V
Sbjct: 23143 YTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIV 23202
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+K + + TV +T +S L+ G Y FRV EN G+ E
Sbjct: 23203 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 23249
Score = 89.4 bits (220), Expect = 5e-18
Identities = 51/201 (25%), Positives = 96/201 (47%), Gaps = 2/201 (0%)
Query: 31 SPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
S + + S P ++ E P++ + R + K G+ + + G+P P W D
Sbjct: 19395 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19454
Query: 91 GCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
G ++ R R + + + ++L +++ R D+G+Y L ++ + ++ V+++PGPP
Sbjct: 19455 GIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPP 19514
Query: 150 QS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
+++ + +L W PQ+ G + Y V+K +T W TSC V+
Sbjct: 19515 AGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTK 19574
Query: 209 LIIGNSYAFRVFAENQCGLSE 229
L+ GN Y FRV N+ G+ E
Sbjct: 19575 LLKGNEYIFRVTGVNKYGVGE 19595
Score = 87.8 bits (216), Expect = 1e-17
Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 1/163 (0%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLR 126
G+ +++ +PF+ P P W DG + R++++N + L + ++ RAD+G Y +
Sbjct: 8029 GEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTIT 8088
Query: 127 VQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKAD 186
++ ATA+I++ VI PGP + IK D+ S L W PP+ G T +L Y +++ +
Sbjct: 8089 LENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERRE 8148
Query: 187 TKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ V+ ++ S V DLI Y FRV A N+ G E
Sbjct: 8149 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGE 8191
Score = 86.3 bits (212), Expect = 4e-17
Identities = 54/187 (28%), Positives = 92/187 (49%), Gaps = 8/187 (4%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
PKI + Q + VG + +++P+ PK +A W + L T+ + EQ S
Sbjct: 6628 PKI---KTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT-TAEQTSFR 6683
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQ 170
+ EA++ D GRY++ +Q +A I++ VI+ PGP +++++ + + +L W P
Sbjct: 6684 IL-EAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPL 6742
Query: 171 DTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGN-SYAFRVFAENQCGLSE 229
G + ++GY V++ D K W + V+ L G Y FRV A N+ G E
Sbjct: 6743 TDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE 6802
Query: 230 TAPITTD 236
P+ TD
Sbjct: 6803 --PVETD 6807
Score = 84.7 bits (208), Expect = 1e-16
Identities = 69/250 (27%), Positives = 111/250 (44%), Gaps = 13/250 (5%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
++G V+L +P++GKPKP W DG L ++ V E L I+ A++ G+Y
Sbjct: 21204 RIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21263
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ + I ++ + P P+ I+ ++ S L W P+D G + Y+++
Sbjct: 21264 VILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 21323
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
K +T W V RT+ V +L+ Y FRV AEN+ G+S+ + +A Q
Sbjct: 21324 KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFR 21383
Query: 244 ATVYKTKGFAQRDFSEAPKFT--QPLAD-CTTVTGYNTQLFCCVRASPRPKIIWLK-NKM 299
K S+ T P+ D + VTG++ V R I+W K N
Sbjct: 21384 IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFH------VEKKERNSILWQKVNTS 21437
Query: 300 DIQGNPKYRA 309
I G +YRA
Sbjct: 21438 PISGR-EYRA 21446
Score = 82.8 bits (203), Expect = 4e-16
Identities = 56/206 (27%), Positives = 90/206 (43%), Gaps = 15/206 (7%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-TVLEHYHRT 202
++P P ++++ + S TL+W P+ G +LGY V+ + W + E
Sbjct: 24057 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 24116
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+ L+ Y FRVFAEN+ GLS ++ A KTK + EAP
Sbjct: 24117 QFTIGGLLEATEYEFRVFAENETGLSRP----------RRTAMSIKTKLTS----GEAPG 24162
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ + D TT G QL C + P P I W + ++ + KY+ + +L +
Sbjct: 24163 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 24222
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRV 348
D G+YTC A N +GE ++
Sbjct: 24223 EEQEDEGVYTCIATNEVGEVETSSKL 24248
Score = 80.5 bits (197), Expect = 2e-15
Identities = 52/183 (28%), Positives = 93/183 (50%), Gaps = 8/183 (4%)
Query: 59 LRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQR 117
L++ Y VG T+ L + + G+P P W H L ++ +++ N E + L ++ QR
Sbjct: 24262 LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQR 24321
Query: 118 -ADSGRYQLRVQLGGLEAT--ATIDILVIERPGPPQSIKLVD-VWGFSATLEWTPPQDTG 173
+G+Y +VQL + T A +D+ + ++P P +++ + SA + W PP D G
Sbjct: 24322 KTHAGKY--KVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24379
Query: 174 NTALLGYTVQKADTKSGL-WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAP 232
+ + Y V+K + K G W V T+C + +L Y FRV A+N G+S+
Sbjct: 24380 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24439
Query: 233 ITT 235
+++
Sbjct: 24440 VSS 24442
Score = 80.1 bits (196), Expect = 3e-15
Identities = 65/221 (29%), Positives = 96/221 (43%), Gaps = 7/221 (3%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKV--GDTV 71
+L + + DA Q GS + +E KI LP+ L G+ V
Sbjct: 24614 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 24673
Query: 72 NLLIPFQGKPKPQAIWTHDGCALDTR---RVSVRNGEQDSILFIREAQRADSGRYQLRVQ 128
++ IPF GKP P W +D +V V S++F +R D+G Y + +
Sbjct: 24674 SIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAGFYVVCAK 24732
Query: 129 LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTK 188
T+++ V + P PP+ +K+ DV S L WT P G + + Y V+K T
Sbjct: 24733 NRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT 24792
Query: 189 SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ W V T V +L SY FRV AEN+ GLS+
Sbjct: 24793 AERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLSK 24832
Score = 79.0 bits (193), Expect = 6e-15
Identities = 63/231 (27%), Positives = 98/231 (42%), Gaps = 34/231 (14%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIR-KVGDTVNLLIPFQGKPKPQAIW 87
+A G P+ + PP + I P+ + +T + K GD + L G P P W
Sbjct: 8283 RAENAAGISEPS-RATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITW 8341
Query: 88 THDGCALD-----------------------------TRRVSVRNGEQ-DSILFIREAQR 117
D + T+R+S+ N ++ +S L +R++ R
Sbjct: 8342 IKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLR 8401
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTAL 177
D G Y ++V+ A A + V++ PGPP + D+ S +W PP D G + +
Sbjct: 8402 PDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEI 8461
Query: 178 LGYTVQKAD-TK-SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
+ YT++K D TK W V V+ LI G Y FRV AEN+ G
Sbjct: 8462 INYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG 8512
Score = 77.0 bits (188), Expect = 2e-14
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
Query: 79 GKPKPQAIWTHDGCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATAT 137
GKP+P+ IWT LD +VS++ + + I+ R+DSG+Y L V+ +
Sbjct: 22701 GKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS 22760
Query: 138 IDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE 197
+ + V++ PGP + + V TL W+ PQ+ G + Y V++ +T W V
Sbjct: 22761 VMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEG 22820
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
S +V+ LI N Y FRV A N+ G
Sbjct: 22821 ECPTLSYVVTRLIKNNEYIFRVRAVNKYG 22849
Score = 75.5 bits (184), Expect = 7e-14
Identities = 53/193 (27%), Positives = 86/193 (44%), Gaps = 4/193 (2%)
Query: 64 IRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGR 122
I K G+++ + QG+P P+ W DG ++ R + + + + LF+R+A R G
Sbjct: 21597 IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGV 21656
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYT 181
Y + + A A I + V + PG I+ ++ G TL W P + G + Y
Sbjct: 21657 YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYI 21716
Query: 182 VQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQ 241
++K +T W + + S LI GN Y FRV A N+ G+ P+ +D Q
Sbjct: 21717 IEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGR--PLDSDPVVAQ 21774
Query: 242 KAATVYKTKGFAQ 254
TV G +
Sbjct: 21775 IQYTVPDAPGIPE 21787
Score = 74.7 bits (182), Expect = 1e-13
Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 2/178 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
P + L ++R + G + ++ GKP P W + L + ++ S +
Sbjct: 10150 PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP-QEATIETTAISSSM 10208
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLV-DVWGFSATLEWTPP 169
I+ QR+ G Y L + E TI + V++ PGP + L ++ S L W P
Sbjct: 10209 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10268
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
+D G + + Y ++K ++ W V R + V LI G +Y FR+ AEN G+
Sbjct: 10269 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGM 10326
Score = 74.3 bits (181), Expect = 2e-13
Identities = 56/212 (26%), Positives = 86/212 (40%), Gaps = 16/212 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A + ERP PP I L+DV S +L W P+ G + +LGY V+ S
Sbjct: 15662 GLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSD 15721
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W T T ++ LI G Y+FRV A+N+ G+S+ ++ +
Sbjct: 15722 KWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPV------------- 15767
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
+D P F T + G + ++ P P + W K+ + ++ + A
Sbjct: 15768 --IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE 15825
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
+ L I+ D G Y K N GEA
Sbjct: 15826 STENNSLLTIKDACREDVGHYVVKLTNSAGEA 15857
Score = 74.3 bits (181), Expect = 2e-13
Identities = 55/216 (25%), Positives = 87/216 (40%), Gaps = 20/216 (9%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEH 198
+L I+ PP+++++ D+ S +L W P G + + GY V++ D G W +
Sbjct: 20390 VLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTN 20449
Query: 199 YHRTSCIVSDLIIGNSYAFRVFAENQCG-LSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
T I+S L + Y FRVFA N G +S + + + I D
Sbjct: 20450 VTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI---------------DS 20494
Query: 258 SEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
P PL V G + +L + P P I W K+ ++Q N
Sbjct: 20495 YGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD 20554
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ S+ I+ + G Y K N +G AS RV +
Sbjct: 20555 LASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 20590
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/226 (24%), Positives = 95/226 (42%), Gaps = 22/226 (9%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNL 73
+ +VK + A P A+ G P + P I+ L++ + G VN+
Sbjct: 9716 EFRVKAVNAAGVSKPSATVGP-CDCQRPDMPPSID----------LKEFMEVEEGTNVNI 9764
Query: 74 LIPFQGKPKPQAIW---------THDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+ +G P P W + DT V+ + L I +++R+D+G Y
Sbjct: 9765 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTH-VNKLVVDDTCTLVIPQSRRSDTGLYT 9823
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ A+ + + V+ RPGPP IK V TL W PP+D G + + Y ++
Sbjct: 9824 ITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIE 9883
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
K + W V + + L+ G+ Y FR+ A+N+ G+ E
Sbjct: 9884 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9929
Score = 73.6 bits (179), Expect = 3e-13
Identities = 58/209 (27%), Positives = 91/209 (43%), Gaps = 20/209 (9%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH--YHRTS 203
PGPP + ++VD S +L WT P G T ++GY ++ + + W+ V + T
Sbjct: 22970 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 23029
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V DL +G Y+FRV A N G+SE + ++ +++ + ++ K
Sbjct: 23030 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIE-------IPDLELADDLKK 23082
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL--THLGICSLEIR 321
T T G + +L V P P I W K +D+ RA+ T L +
Sbjct: 23083 T-----VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS----RAIIDTTESYSLLIVD 23133
Query: 322 KPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
K +D G YT +A N G+ S V V
Sbjct: 23134 KVNRYDAGKYTIEAENQSGKKSATVLVKV 23162
Score = 72.8 bits (177), Expect = 4e-13
Identities = 58/208 (27%), Positives = 87/208 (41%), Gaps = 18/208 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP+++K D S L W PP++ G + + GY V++ S W E T
Sbjct: 7216 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 7275
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF-- 263
V+ L G YA+RV A N+ G S+ + T ++ + D EAP+
Sbjct: 7276 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAV---------------DTQEAPEIFL 7320
Query: 264 -TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ LA T G +L V P PKI W K M ++ + + ++ I
Sbjct: 7321 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVD 7380
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y +AVN G A+ V+V
Sbjct: 7381 SKRSDTGTYIIEAVNVCGRATAVVEVNV 7408
Score = 71.6 bits (174), Expect = 1e-12
Identities = 49/218 (22%), Positives = 86/218 (39%), Gaps = 16/218 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A I V E P PP I + DV S +L WT P+ G + ++ Y V+ S
Sbjct: 16744 GLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE 16803
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W + ++++L G Y FRV A N+ G S+ + +
Sbjct: 16804 KW-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPI------------- 16849
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
+D P + + G + ++ + P+P I W K+ + ++ +
Sbjct: 16850 --VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT 16907
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
L + +L I++ DGG Y N +G+ + +
Sbjct: 16908 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEI 16945
Score = 69.7 bits (169), Expect = 4e-12
Identities = 59/213 (27%), Positives = 82/213 (38%), Gaps = 16/213 (7%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRT 202
E+PG P + V S + W PP G + Y ++K + K W +V E T
Sbjct: 24451 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24510
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
V +LI G Y FRV EN G SE + I+ + +AP
Sbjct: 24511 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPI-------------QAPH 24557
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHL-GICSLEI 320
F + L + N L C V P+P + W + K I KYR G L I
Sbjct: 24558 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLII 24617
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D +Y +A N G S ++V+VP
Sbjct: 24618 ASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 24650
Score = 69.3 bits (168), Expect = 5e-12
Identities = 59/215 (27%), Positives = 88/215 (40%), Gaps = 17/215 (7%)
Query: 137 TID-ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
T+D + E P PP + L DV SA+L W P+ G + +LGY V+ + W V
Sbjct: 17831 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 17890
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR 255
E + +V+ L G Y FRV A N+ G S+ P + I K T+
Sbjct: 17891 AES-KVCNAVVTGLSSGQEYQFRVKAYNEKGKSD--PRVLGVPVIAKDLTI--------- 17938
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
P P + G + ++ V PRP I W+K+ ++ +
Sbjct: 17939 ----QPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATS 17994
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I++ D G YT A N G A+ + V V
Sbjct: 17995 TVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 18029
Score = 68.9 bits (167), Expect = 6e-12
Identities = 60/212 (28%), Positives = 85/212 (40%), Gaps = 23/212 (10%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT---VLEHY 199
I +P PP + + +D S L W PP+ G + +LGY V+ W E
Sbjct: 10738 IAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESC 10797
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
T V+ L G +Y FRV A N G S D AH+ + V +D E
Sbjct: 10798 PETKYKVTGLRDGQTYKFRVLAVNAAGES-------DPAHVPEPVLV--------KDRLE 10842
Query: 260 APKF---TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC 316
P+ + G +L ++ P PK+ W K D + +T +G
Sbjct: 10843 PPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARI-DVTPVG-S 10900
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
LEIR DGGIY+ NP G +V +V
Sbjct: 10901 KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKV 10932
Score = 67.8 bits (164), Expect = 1e-11
Identities = 76/309 (24%), Positives = 123/309 (39%), Gaps = 41/309 (13%)
Query: 48 EEHPKIWLPRALRQTYIR-KVGDTVNLLIPFQGKPKPQAIWTHDGC-------ALDTRRV 99
E P I L ++R I+ K G+ V++ G P P+ W+ + AL +
Sbjct: 9020 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 9079
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWG 159
V E + L I +A R D G Y + + + V +RP PP+++ + D+
Sbjct: 9080 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKA 9139
Query: 160 FSATLEWTPPQDTGNTALLGYTVQKADT--KSGLWFTVLEHYHRTSCIVSDLIIGNSYAF 217
S L W P D G + + Y + K D K W V + LI Y F
Sbjct: 9140 ESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEF 9199
Query: 218 RVFAENQCGLSETAPITTDLAHIQKAATV----YKTKGFAQRDFSEAPKFTQPLAD-CTT 272
RV A N+ G+S+ +D IQ + K K A+ S +T PL + +
Sbjct: 9200 RVRAVNKYGISDEC--KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSP 9257
Query: 273 VTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKY-----RALTHLGICSLEIRKPGPFD 327
+TGY WL+ + +G+P + +T +G+ +E P +
Sbjct: 9258 ITGY-----------------WLEKRE--EGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 9298
Query: 328 GGIYTCKAV 336
G Y +A+
Sbjct: 9299 GVKYQFRAM 9307
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/216 (27%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF------ 193
+LV E P P +++VDV + TL W P G + L GY ++ + W
Sbjct: 23257 VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLK 23316
Query: 194 -TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGF 252
TVLEH V+ L G Y FR+ A+N+ G+SE T A TV +
Sbjct: 23317 PTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETVT-------AVTVQDLRVL 23363
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTH 312
D S T P G +L + P P W ++ + + TH
Sbjct: 23364 PTIDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH 23418
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
+ L IR+ D G YT + N G S +V
Sbjct: 23419 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23454
Score = 67.0 bits (162), Expect = 2e-11
Identities = 57/213 (26%), Positives = 88/213 (41%), Gaps = 22/213 (10%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHR 201
IERP PP ++ D S L+W PP G + +LGY +++ + W ++
Sbjct: 6917 IERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPE 6976
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETA----PITTDLAHIQKAATVYKTKGFAQRDF 257
+ V+ L GN Y +RV AEN+ G+S+ + P+T D A ++ + A +D
Sbjct: 6977 LTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDL-----SAFKDG 7031
Query: 258 SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
E P+ TGY PRP W ++ + + T
Sbjct: 7032 LEV-IVPNPITILVPSTGY-----------PRPTATWCFGDKVLETGDRVKMKTLSAYAE 7079
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I D GIYT K N + S + V+V
Sbjct: 7080 LVISPSERSDKGIYTLKLENRVKTISGEIDVNV 7112
Score = 67.0 bits (162), Expect = 2e-11
Identities = 52/220 (23%), Positives = 82/220 (37%), Gaps = 16/220 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A T + V E P PP + LVDV +AT++W P+ G + + GY V+ S
Sbjct: 18909 GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSE 18968
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W T + +S L G Y FRV A N+ G S+ + +
Sbjct: 18969 KWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV------------- 19014
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
RD P P ++ + P+ + W K+ ++ +
Sbjct: 19015 --IARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVS 19072
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + SL I++ D G Y N G +V + V
Sbjct: 19073 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIV 19112
Score = 66.6 bits (161), Expect = 3e-11
Identities = 59/215 (27%), Positives = 88/215 (40%), Gaps = 21/215 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE--HYH 200
I+ PGPP I++ D S TL W+ P G +A+ GY V+ + W TV
Sbjct: 20792 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20851
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
T +VS+L G +Y FRV A N G E + + +D EA
Sbjct: 20852 TTEYVVSNLKPGVNYYFRVSAVNCAGQGE---------------PIEMNEPVQAKDILEA 20896
Query: 261 PKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P+ +A T+V G + Q+ + P P + W K++ ++ + +Y
Sbjct: 20897 PEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL 20956
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
L I + D G Y N +GE V VKV
Sbjct: 20957 LTIPQVTRNDTGKYILTIENGVGEPK-SSTVSVKV 20990
Score = 65.9 bits (159), Expect = 5e-11
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 19/211 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHR 201
+ PGPP +K+ D + +LEW+ P G ++GY ++ G W V E +
Sbjct: 21879 VNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVK 21938
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
T V+DL G Y FRV A N G ++ +T + + + + D
Sbjct: 21939 TRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTA-------PELDIDANF 21991
Query: 262 KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL--GICSLE 319
K T + G + +LF + P P +W K N RA H +L
Sbjct: 21992 KQTHVVR-----AGASIRLFIAYQGRPTPTAVWSKP----DSNLSLRADIHTTDSFSTLT 22042
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ D G YT N G S+ V V
Sbjct: 22043 VENCNRNDAGKYTLTVENNSGSKSITFTVKV 22073
Score = 63.9 bits (154), Expect = 2e-10
Identities = 57/217 (26%), Positives = 87/217 (40%), Gaps = 21/217 (9%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY 199
++ ++ PP +++++ S TL WT P+ G L GY V+K D S W H
Sbjct: 13896 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKA-NHV 13954
Query: 200 HRTSC--IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
+ C V+DL+ G Y FR+ A+N G +A T+ +D
Sbjct: 13955 NVPECAFTVTDLVEGGKYEFRIRAKNTAGAI--------------SAPSESTETIICKDE 14000
Query: 258 SEAPKFT--QPLADCTTVTGYNTQLF--CCVRASPRPKIIWLKNKMDIQGNPKYRALTHL 313
EAP + D T+ +T + + P PK W K DI+ + + +
Sbjct: 14001 YEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTP 14060
Query: 314 GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I+ D G YT A NP G +V V
Sbjct: 14061 TSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 14097
Score = 63.5 bits (153), Expect = 3e-10
Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 26/215 (12%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW--FTVLEHYH 200
I +PGPP + K++D+ S L W+ P G + GY V+K D G W T +
Sbjct: 16463 IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGIN 16522
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
+T+ V L+ + Y FR+ A N+ G+ E A + + +K EA
Sbjct: 16523 KTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL---------------EA 16567
Query: 261 PKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL--GI 315
P L + G + +LF ++ P P++ W K + G + A+ +
Sbjct: 16568 PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGK----VDGEIRDAAIIDVTSSF 16623
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
SL + +D G YT N G S V V
Sbjct: 16624 TSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRV 16658
Score = 63.2 bits (152), Expect = 3e-10
Identities = 66/274 (24%), Positives = 113/274 (41%), Gaps = 40/274 (14%)
Query: 101 VRNGEQDSILFIREAQRADSGR------------YQLRVQL---GGLEATA-----TIDI 140
V E++SIL+ + SGR YQ RV GL + + T+ +
Sbjct: 21421 VEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAV 21480
Query: 141 LVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYH 200
++ PG P I DV + TL+W PP G + ++GY+++K
Sbjct: 21481 SPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVS 21537
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
V+ L G+ Y FR+ A N G ++ +++ + T RD +
Sbjct: 21538 ECQYTVTGLSPGDRYEFRIIARNAVG---------TISPPSQSSGIIMT-----RDENVP 21583
Query: 261 P--KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P +F D + +G + ++ V+ P P++ W K+ ++I+ LG S
Sbjct: 21584 PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTS 21643
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L +R G+YT +A N G A + +V V+
Sbjct: 21644 LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677
Score = 62.0 bits (149), Expect = 8e-10
Identities = 31/88 (35%), Positives = 48/88 (54%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP+ ++++++ +A L+WT P+ G + + Y V+K D + W TV T C
Sbjct: 7712 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7771
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPI 233
V+ L G+ Y FRV AEN G S+ I
Sbjct: 7772 VTPLTEGSLYVFRVAAENAIGQSDYTEI 7799
Score = 61.2 bits (147), Expect = 1e-09
Identities = 56/213 (26%), Positives = 81/213 (38%), Gaps = 20/213 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRT 202
I+ PGPP + KL D +A L WT P G + +LGY V+ + W + +
Sbjct: 11429 IKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIR 11488
Query: 203 SCI--VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
C V LI GN Y FR+ A N G E + + +D
Sbjct: 11489 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL---------------AESVIAKDILHP 11533
Query: 261 PKFTQPLA--DCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P+ + D TV G ++ V+ P P I W K + + + L
Sbjct: 11534 PEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE 11593
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L+I++ D G Y A N G A V+V
Sbjct: 11594 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNV 11626
Score = 60.8 bits (146), Expect = 2e-09
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 9/142 (6%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
+EA + D+ PGPP ++ + DV F +L W PP+ G + Y ++ D S
Sbjct: 6810 VEARSKYDV-----PGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIR 6864
Query: 192 WFTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGL---SETAPITTDLAHIQKAATVY 247
W T + S V+D++ G Y+FRV A+N+ G+ S P I++ +
Sbjct: 6865 WDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPV 6924
Query: 248 KTKGFAQRDFSEAPKFTQPLAD 269
Q S K+ PL D
Sbjct: 6925 NLTSSDQTQSSVQLKWEPPLKD 6946
Score = 59.7 bits (143), Expect = 4e-09
Identities = 61/221 (27%), Positives = 83/221 (37%), Gaps = 32/221 (14%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ------KADTKSGLW--FT 194
IE PGPP + ++VD S TL W P G ++GY V+ A G W
Sbjct: 12122 IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEG-WKRCN 12180
Query: 195 VLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQ 254
R V+ L Y FRV A+NQ G+ A + +
Sbjct: 12181 AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAEL---------------KEAIKP 12225
Query: 255 RDFSEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
++ E P+ + V G +LF VR P PK+ W K +D N +
Sbjct: 12226 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID---NVVRKGQV 12282
Query: 312 HL--GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L + L I D G Y+ VNP GE +V V V
Sbjct: 12283 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRV 12323
Score = 59.7 bits (143), Expect = 4e-09
Identities = 66/250 (26%), Positives = 94/250 (37%), Gaps = 30/250 (12%)
Query: 114 EAQRADSG-RYQLRVQ----LGGLEATATIDILVIERP-GPPQSIKLVDVWGFSATLEWT 167
+AQ + G Y+ RV +G +A+ + V P PP + + + V TL+WT
Sbjct: 17111 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 17170
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
P G + + GY V+K D G W + T VS L Y FRV A+N G
Sbjct: 17171 KPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG 17230
Query: 227 L-----SETAPITT-DLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQL 280
T PIT D + + S PKF + G +L
Sbjct: 17231 AISKPSDSTGPITAKDEVELPR--------------ISMDPKFRDTI---VVNAGETFRL 17273
Query: 281 FCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
V P P I WL+ +I+ + + L ++ DGG Y +A N G
Sbjct: 17274 EADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 17333
Query: 341 EASVDCRVDV 350
S V V
Sbjct: 17334 SKSFPVNVKV 17343
Score = 59.3 bits (142), Expect = 5e-09
Identities = 46/207 (22%), Positives = 76/207 (36%), Gaps = 17/207 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR--TS 203
P PP + + D + W PP+ G + ++GY V+ + W V +
Sbjct: 7913 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 7972
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
+ ++ Y RV A N G+SE + I+ ++ +D P
Sbjct: 7973 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV---------------VAKDPDCKPTI 8017
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
D + G + RA P P + W K+ +++ + + LE+ K
Sbjct: 8018 DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKS 8077
Query: 324 GPFDGGIYTCKAVNPLGEASVDCRVDV 350
D GIYT N LG A+ V V
Sbjct: 8078 VRADAGIYTITLENKLGSATASINVKV 8104
Score = 59.3 bits (142), Expect = 5e-09
Identities = 56/225 (24%), Positives = 88/225 (39%), Gaps = 30/225 (13%)
Query: 135 TATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT 194
T + I I+RPG P+++ + D L+W P G + L Y V++ S W
Sbjct: 11718 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER 11777
Query: 195 VLE------HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYK 248
V + HY C+ + + Y FRV +N+ G S+ K
Sbjct: 11778 VHKGSIKETHYMVDRCVENQI-----YEFRVQTKNEGGESDWV----------------K 11816
Query: 249 TKGFAQRDFSEAPKFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNK--MDIQGNP 305
T+ ++ + P L+ TV G +L VR P P++ W K+K D+ +P
Sbjct: 11817 TEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP 11876
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + T + K DGG Y A N G V+V
Sbjct: 11877 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11921
Score = 59.3 bits (142), Expect = 5e-09
Identities = 49/210 (23%), Positives = 78/210 (37%), Gaps = 15/210 (7%)
Query: 133 EATATID-ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
E T T + + E P PP S+ ++D+ + +L W P+ G + + GY ++ S
Sbjct: 14579 EPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 14638
Query: 192 WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKG 251
W T + C+V +L G Y F+V A N G S + Q +G
Sbjct: 14639 W-THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRG 14697
Query: 252 FAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
Q+ G N ++ V P+P + W K ++ + T
Sbjct: 14698 IYQK-------------LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFET 14744
Query: 312 HLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
L I + D G Y A N +GE
Sbjct: 14745 TATSTILNINECVRSDSGPYPLTARNIVGE 14774
Score = 58.9 bits (141), Expect = 7e-09
Identities = 52/208 (25%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP + + V S TL+W P G + + GY V+K + G W + T V
Sbjct: 16069 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEV 16128
Query: 207 SDLIIGNSYAFRVFAENQCGL-SETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
+ L+ + Y FRV A N G+ SE + T RD + P+ +
Sbjct: 16129 TGLVEDHRYEFRVIARNAAGVFSEPSE---------------STGAITARDEVDPPRISM 16173
Query: 266 PLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
T+ G + ++ + P P I W+K ++ + + SL ++
Sbjct: 16174 DPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKD 16233
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y KA N GE SV V V
Sbjct: 16234 AVRVDSGNYILKAKNVAGERSVTVNVKV 16261
Score = 58.5 bits (140), Expect = 9e-09
Identities = 51/212 (24%), Positives = 77/212 (36%), Gaps = 35/212 (16%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY 199
I+ E+P PP+ + +VD SA L W P G + + GY ++ S W H
Sbjct: 22168 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHT 22226
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
+ + V L+ Y FRV A+N G SE + F+ E
Sbjct: 22227 KQLTFTVERLVEKTEYEFRVKAKNDAGYSE------------------PREAFSSVIIKE 22268
Query: 260 APKFTQPLADCTTVTGYNTQLFCC-----------VRASPRPKIIWLKNKMDIQGNPKYR 308
+P AD +TG QL C + P PK+ W +M ++ +
Sbjct: 22269 PQ--IEPTAD---LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS 22323
Query: 309 ALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
T +L ++ D G Y N G
Sbjct: 22324 ITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 22355
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/218 (24%), Positives = 81/218 (37%), Gaps = 29/218 (13%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ-----KADTKSGLWFTVLEH-Y 199
P PP +K+ + + L W PP++ G + + Y V+ TK W +
Sbjct: 9640 PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDV 9699
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
V DL+ G Y FRV A N G+S+ + T G +
Sbjct: 9700 EELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS----------------ATVGPCDCQRPD 9743
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-------NKMDIQGNPKYRALTH 312
P G N + ++ P P + W K NK + + L
Sbjct: 9744 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVV 9803
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
C+L I + D G+YT AVN LG AS + R++V
Sbjct: 9804 DDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9841
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/208 (25%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP K+VD + T+ W P G + GYTV+ + W T ++ T
Sbjct: 19712 PSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYT 19771
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF-- 263
+S L G Y FRV + N+ G S+ +D + Q A ++ E P F
Sbjct: 19772 ISGLTTGAEYVFRVKSVNKVGASD----PSDSSDPQIA-----------KEREEEPLFDI 19816
Query: 264 -TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
++ G + + R P P ++W K D++ + T SL I
Sbjct: 19817 DSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLR--TRAYVDTTDSRTSLTIEN 19874
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G YT N L AS+ V V
Sbjct: 19875 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19902
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/212 (21%), Positives = 86/212 (40%), Gaps = 17/212 (8%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
G+ A + + E+P PP+ + + + S +L W P+ G + ++ Y V+ +
Sbjct: 19988 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20047
Query: 191 LWF--TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYK 248
W V + H +VS L + Y FRVFAENQ GLS+ + + ++
Sbjct: 20048 NWVKCAVAKSTHH---VVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEP--- 20101
Query: 249 TKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR 308
+ D P T + G N ++ + P PK+ ++ + ++ ++
Sbjct: 20102 ----PEIDMKNFPSHTVYVR-----AGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFN 20152
Query: 309 ALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
++ +++ D G Y A N G
Sbjct: 20153 TEITAENLTINLKESVTADAGRYEITAANSSG 20184
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 10/106 (9%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L++T T+ P PP + D+ +AT+ WT P+ G + + GY +++ + +G
Sbjct: 11318 LDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREV-TGK 11376
Query: 192 WFTVLEHYHRTSCI-----VSDLIIGNSYAFRVFAENQCGLSETAP 232
W V ++T V+ L GN+Y FRVFAEN GLS+ +P
Sbjct: 11377 WVRV----NKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSP 11418
Score = 57.8 bits (138), Expect = 1e-08
Identities = 55/208 (26%), Positives = 79/208 (37%), Gaps = 29/208 (13%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-----TVLE 197
I+ PG P + + + TL+W P+ TG + Y V+K D +G W +LE
Sbjct: 14985 IDPPGKPVPLNITR---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 15041
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
+ S + D +Y FRV A+N G +D RD
Sbjct: 15042 NEFTVSGLTEDA----AYEFRVIAKNAAGAISPPSEPSD--------------AITCRDD 15083
Query: 258 SEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
EAPK + TV G +L V P P + W K+ +++G K
Sbjct: 15084 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15143
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
+L + D G YT A NP G A
Sbjct: 15144 STNLVNKDSTRRDSGAYTLTATNPGGFA 15171
Score = 56.6 bits (135), Expect = 3e-08
Identities = 46/200 (23%), Positives = 78/200 (39%), Gaps = 17/200 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF--TVLEHYHRTS 203
PGPP + + D SA+L W P G + GY V+ W T T
Sbjct: 14301 PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQ 14360
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
+V DL Y FR+ A N G+ E A + D+ +++ DF +
Sbjct: 14361 FVVPDLQTKEKYNFRISAINDAGVGEPA-VIPDVEIVEREMA---------PDFELDAEL 14410
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
+ L G + ++F ++ P P++ W K+ ++++ + L I +
Sbjct: 14411 RRTL---VVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--LIIPEC 14465
Query: 324 GPFDGGIYTCKAVNPLGEAS 343
+D G + NP G+ S
Sbjct: 14466 NRYDTGKFVMTIENPAGKKS 14485
Score = 55.8 bits (133), Expect = 6e-08
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTSC 204
PGPP+ ++ +V +AT+ W P D G + + GY V++ + KS W ++ C
Sbjct: 14200 PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 14259
Query: 205 IVSDLIIGNSYAFRVFAENQCGL 227
V+ L G++Y FRV AEN+ G+
Sbjct: 14260 KVTGLQEGSTYEFRVSAENRAGI 14282
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/223 (25%), Positives = 88/223 (39%), Gaps = 22/223 (9%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
G T + E P P + + + D S L WT P G + + Y V++
Sbjct: 21076 GEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQ 21135
Query: 191 LWFTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKT 249
W +T I VS L + FRVFA+N+ GLS+ P+T +++ +
Sbjct: 21136 TWSHA--GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD--PVTIGPITVKELIITPEV 21191
Query: 250 KGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA 309
D S+ P A T G+N L + P+P I WLK+ + ++ + R
Sbjct: 21192 ------DLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRF 21240
Query: 310 LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
+L I+ GG YT N + CR+ V +
Sbjct: 21241 SKTENKITLSIKNAKKEHGGKYTVILDNAV------CRIAVPI 21277
Score = 54.7 bits (130), Expect = 1e-07
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 14/159 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ--KADTKSGLWFTVLEHYHRTS 203
PGPP K+ D S +L W P G + ++GY V+ +AD+ + + + ++ +T
Sbjct: 13217 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13276
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V+ L+ Y FRV+A N+ G S+ + + H K + +G D +
Sbjct: 13277 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPD--KHYPKDILI-PPEGELDADLRKT--- 13330
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ 302
G +L+ V+ P PKI W K ++++
Sbjct: 13331 ------LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLR 13363
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query: 146 PGPPQSI-KLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTS 203
P PP + +++DV S +L W+ P+D G + + GY +++ +T + W + T
Sbjct: 23957 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 24016
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAP 232
V+ L+ Y FR+ A+N GLSET+P
Sbjct: 24017 YTVTGLVPDAEYQFRIIAQNDVGLSETSP 24045
Score = 53.9 bits (128), Expect = 2e-07
Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP+S+++ ++ S T+ W P G + ++GY V+K D +SG+ + T
Sbjct: 17447 PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRD-RSGIRWIKCNKRRITDLR 17505
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
V+ L + Y FRV AEN G+ E +P T
Sbjct: 17506 LRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 17536
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 3/136 (2%)
Query: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTG 275
AF+ E +SET +D + T KT+ A S P L D T +
Sbjct: 26438 AFKSIHEKVSKISETKK--SDQKTTESTVT-RKTEPKAPEPISSKPVIVTGLQDTTVSSD 26494
Query: 276 YNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
+ PRP IW K+ I KY+ G LEI K D G+YTC
Sbjct: 26495 SVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTV 26554
Query: 336 VNPLGEASVDCRVDVK 351
N G S C++ +K
Sbjct: 26555 KNSAGSVSSSCKLTIK 26570
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Query: 131 GLEATATIDILV---IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADT 187
G + +T IL+ I+ P PP + DV S L WT P+ G + Y ++ T
Sbjct: 7594 GKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKT 7653
Query: 188 KSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ W V E T ++ L+ G Y+FRV A N+ G SE
Sbjct: 7654 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESE 7695
Score = 52.8 bits (125), Expect = 5e-07
Identities = 27/92 (29%), Positives = 41/92 (44%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P L + T + G + L C + P P + W + I+ + ++ GI L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
R+ D G +TC AVN G S C + V+V
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/211 (25%), Positives = 80/211 (37%), Gaps = 24/211 (11%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
PG P++I + + TL+W P G + + GY V+K D G W + T
Sbjct: 18234 PGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEF 18290
Query: 205 IVSDLIIGNSYAFRVFAENQCG-LSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP-- 261
VS L+ Y FRV A N G SE + + RD +AP
Sbjct: 18291 TVSGLVEDQRYEFRVIARNAAGNFSEPSD---------------SSGAITARDEIDAPNA 18335
Query: 262 KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGN-PKYRALTHLGICSLE 319
D V G L +R P P ++W K+ +++ + + + +L
Sbjct: 18336 SLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLV 18395
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
++ DGG Y K N G S+ V V
Sbjct: 18396 VKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18426
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 9/125 (7%)
Query: 114 EAQRADSG-RYQLRVQLG-------GLEATATIDILVIERPGPPQSIKLVDVWGFSATLE 165
+A R +G YQ RV+ G+ + + + PGPP + ++ V S T+
Sbjct: 14847 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 14906
Query: 166 WTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD-LIIGNSYAFRVFAENQ 224
W P G + +LGY V++ + LW TV + + S L G +Y FRV AEN
Sbjct: 14907 WHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENM 14966
Query: 225 CGLSE 229
G S+
Sbjct: 14967 AGKSK 14971
Score = 50.8 bits (120), Expect = 2e-06
Identities = 55/235 (23%), Positives = 82/235 (34%), Gaps = 46/235 (19%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRTSC 204
P PP +++ + + T+ W PP G + ++GY ++K W EH +
Sbjct: 8208 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8267
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
L G Y FRV AEN G+SE + T + D +APK
Sbjct: 8268 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV---------------DPIDAPKVI 8312
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNK-MDIQGNPKYRALTHLGICSLEIRKP 323
G L + SP P I W+K++ + + K RA + E+++
Sbjct: 8313 L-RTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 8371
Query: 324 GPF----------------------------DGGIYTCKAVNPLGEASVDCRVDV 350
PF D G+Y K N G A C V V
Sbjct: 8372 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8426
Score = 50.8 bits (120), Expect = 2e-06
Identities = 55/221 (24%), Positives = 84/221 (38%), Gaps = 33/221 (14%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH---YHRT 202
PGPP ++ D S +L W PP G + + GY V+ + + W V E
Sbjct: 9333 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9392
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDL--AHIQKAATVYKTKGFAQRDFSEA 260
C+V +L Y FRV A N+ G SE + T ++ IQ+ V+ G
Sbjct: 9393 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIG--------- 9443
Query: 261 PKFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIW-----LKNKM-----DIQGNPKYRA 309
DC G ++ ++ P PK W K M DI + +
Sbjct: 9444 ------AQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLET 9497
Query: 310 LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + + K G Y+ A N G+ + +CRV V
Sbjct: 9498 AENSSVIIIPECKRS--HTGKYSITAKNKAGQKTANCRVKV 9536
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 20/211 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR- 201
I PGPP K+ D SA LEW+PP G + + GY V+ + W + R
Sbjct: 10047 IAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 10105
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
T +V+ L G Y FRV A N G+ E + TD+ ++ R S
Sbjct: 10106 TKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEV-TDVIEMK------------DRLVSPDL 10152
Query: 262 KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI-CSLE 319
+ + D V G ++ V P P + W N+ + P+ + I S+
Sbjct: 10153 QLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL---PQEATIETTAISSSMV 10209
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I+ G+Y+ A N GE VDV
Sbjct: 10210 IKNCQRSHQGVYSLLAKNEAGERKKTIIVDV 10240
Score = 50.8 bits (120), Expect = 2e-06
Identities = 52/206 (25%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PGPP+ + VDV +L W P G + + GY V+ + + W + C+
Sbjct: 11038 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECV 11096
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
V+ L G +Y FRV AEN GL P TT Q ++ + +
Sbjct: 11097 VTGLQQGKTYRFRVKAENIVGLG--LPDTTIPIECQ------------EKLVPPSVELDV 11142
Query: 266 PLADCTTVTGYNTQLF-CCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
L + V T F +R P P W + +I+ + Y T L I+
Sbjct: 11143 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCL 11202
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y N G +V + V
Sbjct: 11203 RRDTGEYQITVSNAAGSKTVAVHLTV 11228
Score = 50.8 bits (120), Expect = 2e-06
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
P PP S+++ V S TL W+ P+ G + + GY +++ + S W V + +
Sbjct: 19611 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 19670
Query: 205 IVSDLIIGNSYAFRVFAENQCGL---SETAPI 233
+ L G Y +RV+AEN GL SET+P+
Sbjct: 19671 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19702
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PGPP + + +V S T+ W P G +A++GY ++ D S LW + RT+
Sbjct: 20298 PGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHF 20357
Query: 206 -VSDLIIGNSYAFRVFAENQCGLSE 229
V+ + G Y FRV+AEN G+ +
Sbjct: 20358 KVTTISAGLIYEFRVYAENAAGVGK 20382
Score = 49.7 bits (117), Expect = 4e-06
Identities = 54/223 (24%), Positives = 89/223 (39%), Gaps = 27/223 (12%)
Query: 137 TIDILVIERP----GPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
T + LVI P P+ +++ +V + TL W PP+ G + ++ Y ++ + +
Sbjct: 10332 TSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10391
Query: 193 FTVL-EHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE----TAPITTDLAHIQKAATVY 247
V ++ V L G++Y +RV A N G + T PIT K
Sbjct: 10392 HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITC------KDELAP 10445
Query: 248 KTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKY 307
T RD K T + + +TG + P+PK+ W K++ D+ + +
Sbjct: 10446 PTLHLDFRD-----KLTIRVGEAFALTGRYS-------GKPKPKVSWFKDEADVLEDDRT 10493
Query: 308 RALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
T +LE K D G Y N G C+V+V
Sbjct: 10494 HIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10536
Score = 49.7 bits (117), Expect = 4e-06
Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 11/90 (12%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV------L 196
I PGPP+++++ DV TL W PP+D G + + GY V++ + ++ W V +
Sbjct: 23557 IRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTM 23616
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
Y T L G Y RV A N G
Sbjct: 23617 TRYRSTG-----LTEGLEYEHRVTAINARG 23641
Score = 49.3 bits (116), Expect = 5e-06
Identities = 51/209 (24%), Positives = 80/209 (38%), Gaps = 17/209 (8%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY-TVQKADTKSGLWFTVLEHYHR 201
+ P PP+ +++ ++ SATL W PP G + GY T + + + +T
Sbjct: 12424 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD 12483
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
S +V+ L G Y FRV A N G+S ++A VY+ K + P
Sbjct: 12484 LSLVVTGLKEGKKYKFRVAARNAVGVSLP----------REAEGVYEAK-----EQLLPP 12528
Query: 262 KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIR 321
K P T G ++ V P P W K + ++ + L I+
Sbjct: 12529 KILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 12587
Query: 322 KPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y+ A N G + +V V
Sbjct: 12588 DVTRKDSGYYSLTAENSSGTDTQKIKVVV 12616
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP + ++ + S + W P D G T + GY ++K D K G+ +T T
Sbjct: 18530 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRD-KEGVRWTKCNKKTLTDLR 18588
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSE 229
V+ L G+SY FRV AEN G+ E
Sbjct: 18589 LRVTGLTEGHSYEFRVAAENAAGVGE 18614
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
A I V + PG P+ + G S TL W P+ G + + Y +++ + KS W V
Sbjct: 21773 AQIQYTVPDAPGIPEPSNIT---GNSITLTWARPESDGGSEIQQYILERREKKSTRWVKV 21829
Query: 196 LEH--YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
+ T V+ L GN Y F V AEN G+ + I+
Sbjct: 21830 ISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGIS 21870
Score = 49.3 bits (116), Expect = 5e-06
Identities = 58/232 (25%), Positives = 90/232 (38%), Gaps = 57/232 (24%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK---ADTKSGLW----FTV 195
++ PG P+ + DV + +L W+ P G + ++GY +++ ++ G W +T+
Sbjct: 22567 VDAPGRPE---VTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTI 22623
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL-----SETAPITTDLAHIQKAATVYKTK 250
+ T +S+ G++Y FRV A+N G+ T P+T
Sbjct: 22624 VSDNFFTVTALSE---GDTYEFRVLAKNAAGVISKGSESTGPVTC--------------- 22665
Query: 251 GFAQRDFSEAPKF---TQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLK--------NK 298
RD PK + D T+ G + L V P PKIIW K K
Sbjct: 22666 ----RDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK 22721
Query: 299 MDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ +Q K RA + C D G YT N G +V V V
Sbjct: 22722 VSLQYTGK-RATAVIKFCDRS-------DSGKYTLTVKNASGTKAVSVMVKV 22765
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/214 (25%), Positives = 84/214 (39%), Gaps = 25/214 (11%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV--QKAD----TKSGLWFTVL 196
I PG PQ+ ++ D S +L W+ P+D G + + GY + QK D TK T +
Sbjct: 23658 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 23717
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRD 256
Y ++ L G Y FRV A N G E A + TV T+ D
Sbjct: 23718 REY-----TLTHLPQGAEYRFRVLACNAGGPGEPAEV---------PGTVKVTEMLEYPD 23763
Query: 257 FSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC 316
+ ++ + + G +L ++ P P W K DI + + T
Sbjct: 23764 YELDERYQEGI---FVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHT 23818
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I++ D G Y N G+ +V +V V
Sbjct: 23819 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23852
Score = 48.9 bits (115), Expect = 7e-06
Identities = 52/211 (24%), Positives = 76/211 (36%), Gaps = 22/211 (10%)
Query: 145 RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ--KADTKSGLWFTVLEHYHRT 202
+PGPP + +VD S TL W P G + +LGY V+ KAD + T T
Sbjct: 17547 KPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVT 17606
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+S L Y RV A N+ GL E + + D EAP+
Sbjct: 17607 RFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTV---------------KPEDKLEAPE 17651
Query: 263 F---TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
++ G + ++ + P P+I W + + + K + + L
Sbjct: 17652 LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLS 17709
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I D G Y K N G S V V
Sbjct: 17710 IDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17740
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/221 (25%), Positives = 87/221 (39%), Gaps = 22/221 (9%)
Query: 140 ILVIERPGPPQS---IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
IL ++ GPP S + + + TL+W P+ G + + GY ++K + V
Sbjct: 8914 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 8973
Query: 197 EHY-HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR 255
+ TS +V +L Y FRV A N+ G SE + + + K + +
Sbjct: 8974 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG 9033
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
D + K +P+ VTG P PKI W KN+ I+ +T +
Sbjct: 9034 DTIKV-KAGEPVHIPADVTGL-----------PMPKIEWSKNETVIEKPTDALQITKEEV 9081
Query: 316 ------CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I K D G YT A N LG + V+V
Sbjct: 9082 SRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 9122
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 123 YQLRV-------QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNT 175
YQ R+ Q LE+ + + PGPP + + S ++W P + G +
Sbjct: 17021 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 17080
Query: 176 ALLGYTVQKADTKSGLWFTVLEH-YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
++GY +++ + S LW V + H T +L G Y FRV+AEN G+ + +
Sbjct: 17081 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKAS 17137
Score = 47.8 bits (112), Expect = 2e-05
Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTSC 204
PGPP ++ D+ + TL W P D G + + GY V++ D + W + T+
Sbjct: 7511 PGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTY 7570
Query: 205 IVSDLIIGNSYAFRVFAENQCG 226
V L Y FRV AEN G
Sbjct: 7571 RVKGLTNKKKYRFRVLAENLAG 7592
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 18/119 (15%)
Query: 123 YQLRVQLG---GLEATATIDILVIER----PGPPQSIKLVDVWGFSATLEWTPPQDTGNT 175
YQ RV+ G+ I+V + PGPP + +V +L W P G +
Sbjct: 21355 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 21414
Query: 176 ALLGYTVQKADTKSGLWFTVLEHYHRTSCI------VSDLIIGNSYAFRVFAENQCGLS 228
+ G+ V+K + S LW V TS I + L+ G Y FRV+AEN GLS
Sbjct: 21415 EVTGFHVEKKERNSILWQKV-----NTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21468
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 37/89 (41%)
Query: 255 RDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
++ S+AP F G N C + P P+I W KN + I +
Sbjct: 26756 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN 26815
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEAS 343
+ SLEIR D G YT KA N G+ S
Sbjct: 26816 VYSLEIRNASVSDSGKYTIKAKNFRGQCS 26844
Score = 47.4 bits (111), Expect = 2e-05
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 3/89 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH--YHRTS 203
P P + +V SA + W P D G + Y ++K +T S W V + + T
Sbjct: 10640 PDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTK 10698
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAP 232
V DL+ G Y FRV AEN+ G+ + +P
Sbjct: 10699 FRVPDLLEGCQYEFRVSAENEIGIGDPSP 10727
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRT 202
++PG P ++ V T+ W PP+ G ++ GY ++K + S W V +
Sbjct: 12022 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPER 12081
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSE 229
V +L+ + Y FRV AEN+ G+ E
Sbjct: 12082 RMKVQNLLPDHEYQFRVKAENEIGIGE 12108
Score = 47.0 bits (110), Expect = 3e-05
Identities = 50/215 (23%), Positives = 76/215 (35%), Gaps = 30/215 (13%)
Query: 145 RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW--FTVLEHYHRT 202
+PGPP + +++D S ++ W P G + + GY V+ A + W T T
Sbjct: 15383 KPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT 15442
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
S ++ L Y R++A N GL E A V T R +
Sbjct: 15443 SYTITGLTENQEYKIRIYAMNSEGLGE-------------PALVPGTPKAEDRMLPPEIE 15489
Query: 263 FTQPLADCTTVTGYNT-QLFCCVRASPRPKIIWLK------NKMDIQGNPKYRALTHLGI 315
L T+ T +LF ++ P P++ W + +K I+ Y L
Sbjct: 15490 LDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI---- 15545
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ FD G Y N G S V V
Sbjct: 15546 ----VGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15576
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
PGPP ++ +VDV L+W PP++ G + Y ++K + W + +
Sbjct: 7812 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7871
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
V+D+I G F+V AEN+ G+ + T L+
Sbjct: 7872 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILS 7905
Score = 46.2 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 73/206 (35%), Gaps = 15/206 (7%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF---TVLEHYHRTSC 204
PP +++DV + +L W P+ G + ++GY V+ W T +
Sbjct: 12820 PPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 12879
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
+ L Y FR A +S + + + T+ + D S A K
Sbjct: 12880 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPV-------TILAENVPPRIDLSVAMKSL 12932
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
T G N L V P P + W K+ ++ + +C+LE+
Sbjct: 12933 -----LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVN 12987
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDV 350
D G YT A N G S ++ V
Sbjct: 12988 RKDSGDYTITAENSSGSKSATIKLKV 13013
Score = 46.2 bits (108), Expect = 4e-05
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
P P++ ++ V S + W P G + +LGY ++K D + W +
Sbjct: 16365 PDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRL 16424
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAP 232
V+ LI + Y FRV AEN GLSE +P
Sbjct: 16425 RVTGLIENHDYEFRVSAENAAGLSEPSP 16452
Score = 45.8 bits (107), Expect = 6e-05
Identities = 27/95 (28%), Positives = 43/95 (45%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P+ Q L T +G + + P+PKI W K + + K + L +L
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ + P D +YTC+A N G A+ + V+VP
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP 3285
Score = 45.8 bits (107), Expect = 6e-05
Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 13/121 (10%)
Query: 120 SGRYQLRVQLG---GLEATATIDILVIERP----GPPQSIKLVDVWGFSATLEWTPPQDT 172
+G+Y+ RV+ G+ D +VI+ P GPP K++ S + WTPP D
Sbjct: 9194 NGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDN 9253
Query: 173 GNTALLGYTVQKADTKSGLWFTVLE------HYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
G + + GY ++K + S W V V L+ G Y FR A N G
Sbjct: 9254 GGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAG 9313
Query: 227 L 227
+
Sbjct: 9314 I 9314
Score = 45.8 bits (107), Expect = 6e-05
Identities = 48/207 (23%), Positives = 76/207 (36%), Gaps = 18/207 (8%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS 203
+ PGP +K+ V S ++ W P G + ++GY V T+ W V++
Sbjct: 13510 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL-SLQ 13567
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
DL G Y FRV AEN+ G + IT +A A KG
Sbjct: 13568 YSAKDLTEGKEYTFRVSAENENGEGTPSEITV-VARDDVVAPDLDLKGL----------- 13615
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
P N +L ++ P P + W K + + + + + +L +
Sbjct: 13616 --PDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDC 13673
Query: 324 GPFDGGIYTCKAVNPLG--EASVDCRV 348
D G YT N G E ++ +V
Sbjct: 13674 QKSDAGKYTITLKNVAGTKEGTISIKV 13700
Score = 45.4 bits (106), Expect = 8e-05
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY--HRTS 203
P PP + V ++WT P+ G + Y V K + KS W V + Y + T
Sbjct: 22868 PSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTR 22927
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSE 229
V+ L+ G Y FRV A N G SE
Sbjct: 22928 LKVTSLMEGCDYQFRVTAVNAAGNSE 22953
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 5/171 (2%)
Query: 61 QTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRR---VSVRNGEQDSILFIREAQR 117
Q+ + G T G P P+ W DG + T V + + + L I +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERPGPPQSI-KLVDVWGFSATLEWTPPQDTG-NT 175
A+SGRY L+ G +AT+T ++LV PP + +L + + + TG T
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT 132
Query: 176 ALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
++ + A+ +S L F + + S ++++ +S + V A N G
Sbjct: 133 PVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/94 (28%), Positives = 41/94 (43%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AP + + G+ + C ++++P + W K +I + K + I SLE
Sbjct: 4461 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4520
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
I + D G YTCKA N G S + V VP
Sbjct: 4521 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4554
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 9/106 (8%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
LE+ + + P PP++ ++ + S + W P G + ++ Y V++ D
Sbjct: 15269 LESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQR 15328
Query: 192 WF-----TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAP 232
W T+ + ++ VS L G+ Y FR+ AEN G+S +P
Sbjct: 15329 WIKCNKKTLTDLRYK----VSGLTEGHEYEFRIMAENAAGISAPSP 15370
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/152 (26%), Positives = 62/152 (40%), Gaps = 18/152 (11%)
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
S I+ +S + V A+N+ G S + I T A ++ K P
Sbjct: 1468 SLIIVPATPSDSGEWTVVAQNRAGRSSISVILT------VEAVEHQVK----------PM 1511
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN--PKYRALTHLGICSLEI 320
F + L + G ++ +P P I+WLKN I + PK R G +L+I
Sbjct: 1512 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKI 1571
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
D YT A+N G + C+V+V+V
Sbjct: 1572 DSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
P P + DV S ++W P+D G+ +LGY ++K + S W V + +
Sbjct: 8531 PDAPDKPIVEDVTSNSMLVKWNEPKDNGSP-ILGYWLEKREVNSTHWSRVNKSLLNALKA 8589
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAP 232
V L+ G +Y FRV AEN G + +P
Sbjct: 8590 NVDGLLEGLTYVFRVCAENAAGPGKFSP 8617
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 133 EATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
E++A + PGPP + K+V + + W P + G + ++GY ++ + S LW
Sbjct: 19202 ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILW 19261
Query: 193 FTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ T VS L G Y +RV+AEN G+ +
Sbjct: 19262 SKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGK 19299
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/208 (22%), Positives = 81/208 (38%), Gaps = 22/208 (10%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP ++ ++ S +L+W+ P G + GY V++ + G W + T V
Sbjct: 19315 PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEV 19374
Query: 207 SDLIIGNSYAFRVFAENQC-GLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
++L Y FRVFA N +SE + T + +D E P+
Sbjct: 19375 TELTEDQRYEFRVFARNAADSVSEPSESTGPI---------------IVKDDVEPPRVMM 19419
Query: 266 PL--ADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ D V G ++ + P P I W K+ ++I+ + ++ L ++
Sbjct: 19420 DVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKD 19479
Query: 323 PGPFDGGIYTCKAVNPLGEAS--VDCRV 348
D G Y N G S V+C+V
Sbjct: 19480 CIRRDTGQYVLTLKNVAGTRSVAVNCKV 19507
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PG P + V S T+ W P+ G + + GY ++ DT S W V + +
Sbjct: 9945 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 10004
Query: 206 -----VSDLIIGNSYAFRVFAENQCGL 227
V+ LI G+ Y FRV+A N G+
Sbjct: 10005 GVSYKVTGLIEGSDYQFRVYAINAAGV 10031
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/216 (25%), Positives = 80/216 (37%), Gaps = 30/216 (13%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRT 202
I PGPP ++ D + LEW PP G ++GY V K + W E +
Sbjct: 8628 ISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKV 8686
Query: 203 -SCIVSDLIIGNSYAFRVFAENQCG---LSETAPITTDLAHIQKAATV---YKTKGFAQR 255
V ++ G Y RV A N G ET P+T +A Q+ V KG Q
Sbjct: 8687 RQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVT--VAEPQEPPAVELDVSVKGGIQ- 8743
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
+ G ++ V P P +W K + ++ + + ++G
Sbjct: 8744 ----------------IMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRV--VIDNVGT 8785
Query: 316 CS-LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
S L I+ D G Y A N G RV+V
Sbjct: 8786 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8821
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 248 KTKGFAQRDFS--EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNP 305
K + +Q+ F+ AP+ T + G NT+ V++ P ++ W N +++Q +
Sbjct: 25987 KYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS 26046
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
K G+ +LEI D G Y N GEAS +DV
Sbjct: 26047 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L++ A I + PGPP + + + ++W P + G T ++GY +++ + S L
Sbjct: 18119 LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 18178
Query: 192 WFTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
W + + T + L G Y F+V AEN G+ + + ++
Sbjct: 18179 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVS 18222
Score = 42.7 bits (99), Expect = 5e-04
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL++ + + P P +VDV S +L WT P+ TG + + GY ++ + S
Sbjct: 13789 GLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSL 13848
Query: 191 LWFTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSE 229
LW + R V+ L G Y FRV A N G+ +
Sbjct: 13849 LWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGK 13888
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)
Query: 248 KTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ---GN 304
K + R P+FT PL + T G N + + P P + W K+ I+ +
Sbjct: 25305 KRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDND 25364
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
KY + G+ L I D YT A N GE S ++ V
Sbjct: 25365 KKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR-TSC 204
P P++ ++ V + W P G + ++GY +++ + S LW + R T
Sbjct: 12720 PSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEY 12779
Query: 205 IVSDLIIGNSYAFRVFAENQCGLS 228
+ L+ G Y+FR++A N+ G S
Sbjct: 12780 PCAGLVEGLEYSFRIYALNKAGSS 12803
Score = 41.6 bits (96), Expect = 0.001
Identities = 49/211 (23%), Positives = 75/211 (35%), Gaps = 26/211 (12%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL--EHYHRTS 203
PGPP + K+ D S +L W+ P G + GY V+ + + W T
Sbjct: 18631 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 18690
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V+ L Y FR+ A N G+ E A + + ++ E P+
Sbjct: 18691 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERI---------------EPPEI 18735
Query: 264 TQPLADCTTV----TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AD V +LF ++ P P++ W K + + + + L
Sbjct: 18736 ELD-ADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLV 18792
Query: 320 IRKPGPFDGGIYTCKAVNPLGE--ASVDCRV 348
I FD G Y N G A V+ RV
Sbjct: 18793 IDNVTRFDSGRYNLTLENNSGSKTAFVNVRV 18823
Score = 41.2 bits (95), Expect = 0.001
Identities = 59/289 (20%), Positives = 115/289 (39%), Gaps = 27/289 (9%)
Query: 79 GKPKPQAIWTHDGCALDT--RRVSVRNGEQDSILFIREAQRADSGRY--QLRVQLGGLEA 134
G+P+P+ W + L T + + +G++ ++L I EA D+ Y + + G
Sbjct: 3218 GRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLI-EAFPEDAAVYTCEAKNDYGVATT 3276
Query: 135 TATIDILVIERPGPPQSIK-----LVDVWGFSATLEWTPPQD----TGNTALLGYTVQKA 185
+A++ + V E P Q + ++ + T E P + +G + + +
Sbjct: 3277 SASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDK 3336
Query: 186 DTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG-LSETAPITTD-LAHIQKA 243
K +F + + +++ + + A N G +S TA ++ + + ++
Sbjct: 3337 KIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEGFSKFEEN 3396
Query: 244 AT-----VYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNK 298
+ V + F + + P F QPL+ G + V P+P+I W N+
Sbjct: 3397 TSNSQWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQ 3456
Query: 299 MDIQGNPKYRALTHL----GICSLEIRKPGPFDGGIYTCKAVNPLGEAS 343
I P + H G+ + I G Y+CKA N GEA+
Sbjct: 3457 QLIL--PTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEAT 3503
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 13/100 (13%)
Query: 141 LVIERPG-PPQSIKLVDVWGFSA---TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
++ E P PP + +V+ SA ++ W P G + ++GY V+K + + LW
Sbjct: 22460 IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWV--- 22516
Query: 197 EHYHRTSCI-----VSDLIIGNSYAFRVFAENQCGLSETA 231
++ C+ V+ L+ G Y FR +A N G+S+ +
Sbjct: 22517 -KENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22555
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 236 DLAHIQKAATVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIW 294
D +Q A +KT A E P +FT+PL D T G L C V + K+ W
Sbjct: 5889 DAGEVQLTAKDFKTH--ANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKW 5945
Query: 295 LKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
KN +I + KY + + L I P D YTC A + C ++V P+
Sbjct: 5946 FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA----KDFKTSCNLNVVPPH 6001
Score = 39.7 bits (91), Expect = 0.004
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L + T+ + PGPP + + S ++W P G + ++GY +++ + S L
Sbjct: 15955 LNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSIL 16014
Query: 192 WFTVLEH-YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
W + + +T + L G Y FRV AEN G+ + + ++
Sbjct: 16015 WVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 16058
Score = 39.7 bits (91), Expect = 0.004
Identities = 55/295 (18%), Positives = 110/295 (37%), Gaps = 32/295 (10%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQLR 126
G V G+P P+ W + + + VS+ L IR A +DSG+Y ++
Sbjct: 26776 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 26835
Query: 127 VQ--LGGLEATATIDIL-VIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLG---- 179
+ G ATA++ +L ++E P ++ +G+T+L G
Sbjct: 26836 AKNFRGQCSATASLMVLPLVEEPSREVVLR-----------------TSGDTSLQGSFSS 26878
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPI-TTDLA 238
+VQ + +K F+ +S ++ + E+ +S ++ + +++
Sbjct: 26879 QSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT 26938
Query: 239 HIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWL--K 296
++ + + G PK +D + G + C P P++ W
Sbjct: 26939 QLESSTSKMLKAGIR----GIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26994
Query: 297 NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
K+ Q ++ + +L I DGG+YT N G S + ++
Sbjct: 26995 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 27049
Score = 39.3 bits (90), Expect = 0.005
Identities = 59/346 (17%), Positives = 123/346 (35%), Gaps = 52/346 (15%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLI 75
K+ E +D + +++ + P+ PI P I L+ T + +
Sbjct: 26448 KISETKKSDQKTTESTVTRKTEPKAPE---PISSKPVI--VTGLQDTTVSS-DSVAKFAV 26501
Query: 76 PFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQ--LGGL 132
G+P+P AIWT DG A+ + + + L I + +DSG Y V+ G +
Sbjct: 26502 KATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSV 26561
Query: 133 EATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
++ + I I + Q + + + ++ AL ++ ++ KS
Sbjct: 26562 SSSCKLTIKAI-KDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKS--- 26617
Query: 193 FTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGF 252
+ + L E A ++K+A K
Sbjct: 26618 -----------------------------QEKLALKEEASKVLISEEVKKSAATSLEKSI 26648
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYNTQ--------LFCCVRASPRPKIIWLKNKMDIQGN 304
+ ++ + ++ + + ++TQ L + + W+ N +++ +
Sbjct: 26649 VHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNS 26708
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+YR +L I++ D GI TC ++ E V C+ D+
Sbjct: 26709 EEYRYGVSGSDQTLTIKQASHRDEGILTC--ISKTKEGIVKCQYDL 26752
Score = 38.9 bits (89), Expect = 0.007
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 163 TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFA 221
T+ W PP D G + + GY ++K +T++ W V + + + L G Y FRV A
Sbjct: 13133 TVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTA 13192
Query: 222 ENQCG 226
N+ G
Sbjct: 13193 INKAG 13197
Score = 38.5 bits (88), Expect = 0.009
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 25/162 (15%)
Query: 2 EAATAPEVAAGSKLKVKEA-----SPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLP 56
EA E AA K +K SP +AE + PG G P +E P +
Sbjct: 4686 EAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPP-------DEAPFTYQL 4738
Query: 57 RALRQTYIRKVGDTVNLLIPFQGKP-------KPQAI---WTHDGCAL--DTRRVSVRNG 104
+A+ +++++ D + F G P W DG + + + +G
Sbjct: 4739 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADG 4798
Query: 105 EQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERP 146
+ D L I + Q +D+G Y ++LG E T+T ++V E P
Sbjct: 4799 K-DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP 4839
Score = 38.1 bits (87), Expect = 0.012
Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 3/115 (2%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWT 88
+A+ G G + T +LL E P ++ R T + G V L + G P P +
Sbjct: 81 KATNGSGQATSTAELLVKAETAPPNFVQRLQSMTV--RQGSQVRLQVRVTGIPTPVVKFY 138
Query: 89 HDGCALDTRRVSVRNGEQDSI-LFIREAQRADSGRYQLRVQLGGLEATATIDILV 142
DG + + + E D L I EA DSG Y + AT+T ++LV
Sbjct: 139 RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 37.0 bits (84), Expect = 0.027
Identities = 23/83 (27%), Positives = 37/83 (44%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P F Q L T G +L V P P + + ++ +IQ + ++ + SL I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 321 RKPGPFDGGIYTCKAVNPLGEAS 343
+ P D G Y+ A N +G A+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRAT 186
Score = 36.6 bits (83), Expect = 0.035
Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 22/126 (17%)
Query: 13 SKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKV----- 67
+++ SPA P + SPG+ +EE + L R + ++ K
Sbjct: 1374 ARMSPARMSPARMSPARMSPGRR-----------LEETDESQLERLYKPVFVLKPVSFKC 1422
Query: 68 --GDTVNLLIPFQGKPKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIREAQRADSGR 122
G T + G+P P+ W HDG + T +V ++ S++ + A +DSG
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGE 1481
Query: 123 YQLRVQ 128
+ + Q
Sbjct: 1482 WTVVAQ 1487
Score = 35.4 bits (80), Expect = 0.078
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 258 SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN--PKYRALTHLGI 315
++AP FTQPL + G + P P++ W ++ I + P + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L I + G Y+ KA N G+A+ + VK
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA-LTHLGICSLEIR 321
F + + + G C + P PKI W K+ I+ +Y+ G SL I
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 322 KPGPFDGGIYTCKAVNPLGEA 342
P D GIYT A N G A
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNA 1327
Score = 34.7 bits (78), Expect = 0.13
Identities = 18/64 (28%), Positives = 27/64 (42%)
Query: 288 PRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCR 347
P + WL + ++ + R + G CSL+ D GI TC+A N G
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745
Query: 348 VDVK 351
+ VK
Sbjct: 1746 LIVK 1749
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPK-YRALTHLGICS 317
EAPK + + T G + V P P+ W KN + I+ + + Y +C
Sbjct: 2030 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2089
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEAS 343
L IR D KA+N GE S
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETS 2115
Score = 33.9 bits (76), Expect = 0.23
Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL-GICSLE 319
P F + L G V P P + W K + + Y + + G +
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759
Query: 320 IRKPGPFDGGIYTCKAVNPLGEAS 343
+ P D G+Y CKA N LGE++
Sbjct: 3760 VNDPQREDSGLYICKAENMLGEST 3783
Score = 33.9 bits (76), Expect = 0.23
Identities = 64/278 (23%), Positives = 101/278 (36%), Gaps = 41/278 (14%)
Query: 69 DTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRV 127
DT+ L+ KP + IW D ++T R + + IL I+ A D+G Y R+
Sbjct: 6106 DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRL 6164
Query: 128 QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ-KAD 186
+ + L E PQ++++ LE + + + + VQ K D
Sbjct: 6165 PSSRTDGKVKVHELAAEFISKPQNLEI---------LEGEKAEFVCSISKESFPVQWKRD 6215
Query: 187 TK---SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
K SG + V+ + +V D + + + V G + A AH+
Sbjct: 6216 DKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAA------AHL--- 6262
Query: 244 ATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
TV E + PL D T V +F C + K W +N+ I
Sbjct: 6263 -TVI-----------EKLRIVVPLKD-TRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFD 6309
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
+ KY L + +L IR D Y N GE
Sbjct: 6310 SSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGE 6347
Score = 33.5 bits (75), Expect = 0.30
Identities = 17/61 (27%), Positives = 26/61 (42%)
Query: 291 KIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
++ W ++ + KY G+ L ++ D G Y CK VN GE S + V
Sbjct: 25227 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25286
Query: 351 K 351
K
Sbjct: 25287 K 25287
Score = 33.1 bits (74), Expect = 0.39
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 260 APKF-TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL--THLGIC 316
AP F T+P+ V G + C V +P+P + W K+ + + +Y+ G C
Sbjct: 1035 APYFITKPVVQ-KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGEC 1093
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEAS 343
L I D G YT N GE S
Sbjct: 1094 KLVISMTFADDAGEYTIVVRNKHGETS 1120
Score = 32.7 bits (73), Expect = 0.51
Identities = 21/74 (28%), Positives = 29/74 (39%)
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
FTQ L D F C + P K+ W K+ M++ KYR + + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILT 2189
Query: 323 PGPFDGGIYTCKAV 336
D Y+C V
Sbjct: 2190 IDTSDAEDYSCVLV 2203
Score = 32.0 bits (71), Expect = 0.86
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
Query: 246 VYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNP 305
VY TK ++++ P F + +++ G L V P+PKI W N + + +
Sbjct: 3568 VYPTKFDSEKE-GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSA 3626
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
Y+ + SL I D G YTC A N G+
Sbjct: 3627 DYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGK 3662
Score = 31.2 bits (69), Expect = 1.5
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 245 TVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
T + K A+ EAP +F + L D TVT ++ +F C + + + W +N +I+
Sbjct: 6434 TAGQDKSVAELLIIEAPTEFVEHLED-QTVTEFDDAVFSCQLSREKANVKWYRNGREIKE 6492
Query: 304 NPKYR 308
KY+
Sbjct: 6493 GKKYK 6497
Score = 30.8 bits (68), Expect = 1.9
Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 12/114 (10%)
Query: 79 GKPKPQAIWTHDGCALDTR--RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATA 136
G+P P W + L T + N + + QR DSG Y + + E+T
Sbjct: 3725 GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTC 3784
Query: 137 TIDILVIERPGPPQSIKLVDVWGFSATLEWTP--PQDTGNTALLGYTVQKADTK 188
++LV+ ++ D+ + TP P+D T L G V+ D++
Sbjct: 3785 AAELLVL--------LEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSE 3830
Score = 30.4 bits (67), Expect = 2.5
Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQD---SILFIREAQRADSGRYQ 124
G+TV G PKP+ W H+ + + V + E+ +++ I +A +G+Y
Sbjct: 3433 GETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHAGQYS 3492
Query: 125 LRVQLGGLEATATIDILVIERPGPPQSI 152
+ EAT + V P P+SI
Sbjct: 3493 CKAANSAGEATCAATLTV--TPKAPESI 3518
Score = 30.0 bits (66), Expect = 3.3
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 275 GYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCK 334
G + C V P+PK+ W N I+ + ++R + + GI L+I +D G
Sbjct: 1809 GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFR-VRYDGIHYLDIVDCKSYDTGEVKVT 1867
Query: 335 AVNPLGEASVDCRVDVK 351
A NP G +++++
Sbjct: 1868 AENPEGVIEHKVKLEIQ 1884
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPK-IIWLKNKMDIQGNPKYRALTHLGICS 317
EA K + L + T VT +F P K + W+KN + ++ N KY I S
Sbjct: 2659 EAVKIKKTLKNLT-VTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYS 2717
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L I+ D +Y + LG R+ V+
Sbjct: 2718 LRIKNCAIVDESVYGFR----LGRLGASARLHVE 2747
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 113 bits (283), Expect = 2e-25
Identities = 66/177 (37%), Positives = 97/177 (54%), Gaps = 5/177 (2%)
Query: 62 TYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADS 120
+Y +VG + + +P G+PKP WT DG L T R++V + + L I+E + D
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 16800
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLG 179
G+Y + V + TA+I+I+ +++P PP+ +K DV S TL W PP TG +
Sbjct: 16801 GQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITN 16860
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETAPI 233
Y VQK DT + +W V RT+ V+ L G Y FR+FAEN+ G S E+ PI
Sbjct: 16861 YIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPI 16917
Score = 112 bits (280), Expect = 5e-25
Identities = 67/189 (35%), Positives = 100/189 (52%), Gaps = 4/189 (2%)
Query: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRV 99
P + IE P + LP T+ K + + + +PF+G+P+ W DG L +T RV
Sbjct: 18888 PVIARDIEIKPSVELPF---HTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRV 18944
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWG 159
+V + + + L I+EA + D G Y+L V T I I+V++RPGPP I++ +V
Sbjct: 18945 NVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSC 19004
Query: 160 FSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRV 219
S T+ W PP+ G + Y V+K +T S W V + RTS + L G+ Y FRV
Sbjct: 19005 DSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRV 19064
Query: 220 FAENQCGLS 228
AEN+ G S
Sbjct: 19065 CAENRYGKS 19073
Score = 110 bits (275), Expect = 2e-24
Identities = 67/212 (31%), Positives = 105/212 (49%), Gaps = 8/212 (3%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLI 75
+VK + A P + S PQ+ EE P + +R+T I K G + + +
Sbjct: 19659 RVKSVNKVGASDP-------SDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTV 19711
Query: 76 PFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEAT 135
PF+G+P P +W+ L TR V + + L I A R DSG+Y L +Q A+
Sbjct: 19712 PFRGRPVPNVLWSKPDTDLRTRAY-VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAAS 19770
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
T+ + V++ PGPP +I + DV SA L W P++ G + Y ++K + W +V
Sbjct: 19771 LTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSV 19830
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
+ +R S V++L G Y FRV EN+ G+
Sbjct: 19831 TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19862
Score = 108 bits (270), Expect = 7e-24
Identities = 64/185 (34%), Positives = 101/185 (54%), Gaps = 6/185 (3%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD-GCALDTRRVSVRNGEQDSI 109
P+I L LR+ + T+ L +P +G+P P+ W D G +LD + S+ + ++
Sbjct: 15361 PEIELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLD--KASIESTSSYTL 15418
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPP 169
L + R DSG+Y L V+ +A +++ V++ PGPPQ +K+ +V S TL W PP
Sbjct: 15419 LIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPP 15478
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL-- 227
G + + Y V+K ++ + TV + H+TS V L G SY FRV AEN+ G+
Sbjct: 15479 LLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGL 15538
Query: 228 -SETA 231
+ETA
Sbjct: 15539 PAETA 15543
Score = 108 bits (270), Expect = 7e-24
Identities = 68/206 (33%), Positives = 102/206 (49%), Gaps = 6/206 (2%)
Query: 35 GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G G P P I E P+I L ALR + I K G+ V +LIPF+G+P P W D
Sbjct: 20752 GQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKD 20811
Query: 91 GCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG-GLEATATIDILVIERPGP 148
L + R S+ N + S+L I + R D+G+Y L ++ G G ++T+ + V++ P
Sbjct: 20812 EKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAA 20871
Query: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
Q +++ V + TL W PP G + ++ Y ++K D W V TS + D
Sbjct: 20872 CQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLID 20931
Query: 209 LIIGNSYAFRVFAENQCGLSETAPIT 234
L + FRV AEN+ G+ E T
Sbjct: 20932 LSEKTPFFFRVLAENEIGIGEPCETT 20957
Score = 107 bits (266), Expect = 2e-23
Identities = 75/252 (29%), Positives = 122/252 (48%), Gaps = 14/252 (5%)
Query: 57 RALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREA 115
+ L T+ G+ + + +PF G+P P W D L T RV+ + E +S+L I++A
Sbjct: 15654 KLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDA 15713
Query: 116 QRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGN 174
R D G Y +++ EA T++++V+++PGPP +K+ +V S TL W PP+ G
Sbjct: 15714 CREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGG 15773
Query: 175 TALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETA 231
+++ Y V+K DT + W V RT+ L G Y FR+ AEN+ G S +
Sbjct: 15774 SSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSE 15833
Query: 232 PITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLAD-CTTVTGYNTQLFCCVRASPRP 290
P + RD E ++ +P++D + V GY+ + R
Sbjct: 15834 PTVAQYPFKVPGPPGTPVVTLSSRDSMEV-QWNEPISDGGSRVIGYH------LERKERN 15886
Query: 291 KIIWLK-NKMDI 301
I+W+K NK I
Sbjct: 15887 SILWVKLNKTPI 15898
Score = 106 bits (265), Expect = 3e-23
Identities = 62/192 (32%), Positives = 102/192 (53%), Gaps = 6/192 (3%)
Query: 39 PTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR- 97
P L+PP E L LR+T I + G T+ L +P +G+P P+ W+ L R
Sbjct: 13187 PKDILIPPEGE-----LDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRI 13241
Query: 98 RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDV 157
+ +++ + D+ L + D+G+Y L ++ + TI + V++ PGPP ++ + ++
Sbjct: 13242 GLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEI 13301
Query: 158 WGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAF 217
SA + W PP G + ++ Y VQK D + W TV +TS V++L G SY F
Sbjct: 13302 SKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFF 13361
Query: 218 RVFAENQCGLSE 229
RVFAEN+ G+ +
Sbjct: 13362 RVFAENEYGIGD 13373
Score = 105 bits (263), Expect = 5e-23
Identities = 62/203 (30%), Positives = 100/203 (49%), Gaps = 7/203 (3%)
Query: 41 PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRV 99
P + + P + LP TY + G+ + + IP G+P+P W DG L T RV
Sbjct: 17805 PVIAKDLTIQPSLKLPF---NTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRV 17861
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVW 158
+V ++L I+E + D G+Y + AT + ++V+E+PGPP ++ +V
Sbjct: 17862 NVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVS 17921
Query: 159 GFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFR 218
+ W PP TG + Y V+K DT + W V RT+ ++ L G Y FR
Sbjct: 17922 ADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFR 17981
Query: 219 VFAENQCGLSETAPITTDLAHIQ 241
+FAEN+ G ++AP+ + +Q
Sbjct: 17982 IFAENRYG--KSAPLDSKAVIVQ 18002
Score = 104 bits (259), Expect = 1e-22
Identities = 71/226 (31%), Positives = 104/226 (46%), Gaps = 13/226 (5%)
Query: 12 GSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTV 71
G K K + A+ +G QLLPP KI +P + K G +
Sbjct: 12369 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPP-----KILMPEQITI----KAGKKL 12419
Query: 72 NLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG 130
+ GKP P W + + + ++V + SIL I++ R DSG Y L +
Sbjct: 12420 RIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 12479
Query: 131 GLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKS 189
T I ++V++ PGPPQ + D+ + +L W P + G + + Y V+K D
Sbjct: 12480 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSR 12539
Query: 190 GLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITT 235
G W T L +TSC V LI G Y FRV AEN+ G+SE P+T+
Sbjct: 12540 GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISE--PLTS 12583
Score = 103 bits (257), Expect = 2e-22
Identities = 60/191 (31%), Positives = 97/191 (50%), Gaps = 4/191 (2%)
Query: 48 EEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQ 106
+E P+I+L L K G + L GKP+P+ WT L +R+++ N +
Sbjct: 7188 QEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPK 7247
Query: 107 DSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEW 166
S + I +++R+D+G Y + ATA +++ V+++PGPP + + DV S L W
Sbjct: 7248 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7307
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
PP+D G + + Y V++ T S +W + T+ + LI Y FRV AEN G
Sbjct: 7308 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYG 7367
Query: 227 LSE---TAPIT 234
+ E +PIT
Sbjct: 7368 VGEPVQASPIT 7378
Score = 102 bits (255), Expect = 4e-22
Identities = 57/204 (27%), Positives = 101/204 (49%), Gaps = 6/204 (2%)
Query: 36 AGSPTPQLLPPIE-----EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
AG P ++P +E P L LR+T + + G ++ + +P +G+P P+ WT D
Sbjct: 14257 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14316
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
L R ++ N E ++L I E R D+G++ + ++ + + +++ V++ PGP
Sbjct: 14317 NINLKNR-ANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVL 14375
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
+++ D+ S TL W P G + + Y V+K + + T H+ + V+ L
Sbjct: 14376 NLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLS 14435
Query: 211 IGNSYAFRVFAENQCGLSETAPIT 234
G Y FRV AEN+ G+ E T
Sbjct: 14436 EGCEYFFRVMAENEYGIGEPTETT 14459
Score = 102 bits (253), Expect = 7e-22
Identities = 61/190 (32%), Positives = 89/190 (46%), Gaps = 2/190 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDT-RRVSVRNGEQDSI 109
P + L L + + K G TV +G P P A WT DG + T +V S+
Sbjct: 11011 PSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSV 11070
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L I+ R D+G YQ+ V T + + V++ PGPP I ++DV T+ W P
Sbjct: 11071 LTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP 11130
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P+D G + ++ Y V+K DT+ W V +T + L G Y FRV AEN+ G+
Sbjct: 11131 PKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVG 11190
Query: 229 ETAPITTDLA 238
T +A
Sbjct: 11191 PPLDSTPTVA 11200
Score = 101 bits (252), Expect = 9e-22
Identities = 61/176 (34%), Positives = 93/176 (52%), Gaps = 10/176 (5%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCALD---TRRVSVRNGEQDSILFIREAQRADSGR 122
K GDT+ L +GKP P+ WT D A D + RV + S + +A+R+D G+
Sbjct: 11717 KAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGK 11776
Query: 123 YQLRVQ--LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY 180
Y + G A AT+++L ++PGP +++K+VDV T+ W PP+D G + Y
Sbjct: 11777 YVVTATNTAGSFVAYATVNVL--DKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNY 11834
Query: 181 TVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL---SETAPI 233
++K +TK +W T V+ LI GN Y FRV AEN+ G +E+ P+
Sbjct: 11835 ILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPV 11890
Score = 101 bits (252), Expect = 9e-22
Identities = 61/199 (30%), Positives = 96/199 (48%), Gaps = 2/199 (1%)
Query: 32 PGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDG 91
PG+ A P + + E+P L ++ + G + L IP +GKP P WT +G
Sbjct: 23618 PGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG 23677
Query: 92 CALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS 151
+ ++R + E + L I+EA R DSG Y L ++ + I + VI P P+
Sbjct: 23678 QDI-SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEG 23736
Query: 152 -IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
++ D+ S + W PP D G +LGY +++ + W+T+ TS +V L
Sbjct: 23737 PLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRGTSLVVKGLK 23796
Query: 211 IGNSYAFRVFAENQCGLSE 229
Y FRV AENQ G+S+
Sbjct: 23797 ENVEYHFRVSAENQFGISK 23815
Score = 101 bits (251), Expect = 1e-21
Identities = 86/307 (28%), Positives = 134/307 (43%), Gaps = 30/307 (9%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRR-VSVRNGEQDSI 109
P I LP + + G +V L GKP P W D L T V V N +
Sbjct: 20373 PVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLAS 20432
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
+ I++A R +SG Y+L+++ A+ATI + ++++PGPP I+ V TL W P
Sbjct: 20433 ILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRP 20492
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P D G + Y V+K +T +W V EH + +I GN Y FRV A N+ G+
Sbjct: 20493 PADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIG 20552
Query: 229 ETAPITTDLAHIQKAATVYKTKGFAQ----RDFSEAPKFTQPLAD-CTTVTGY------- 276
E P+ +D + A G + S +++P+AD + ++GY
Sbjct: 20553 E--PLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDK 20610
Query: 277 -NTQLFCCVRAS---PRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYT 332
+ F ++ + R K+ L D Q YR +C++ GPF
Sbjct: 20611 KSLGWFKVLKETIRDTRQKVTGLTENSDYQ----YR------VCAVNAAGQGPFSEPSEF 20660
Query: 333 CKAVNPL 339
KA +P+
Sbjct: 20661 YKAADPI 20667
Score = 100 bits (248), Expect = 3e-21
Identities = 58/170 (34%), Positives = 89/170 (52%), Gaps = 4/170 (2%)
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWT--HDGCALDTRRVSVRNGEQDSILFIREAQRADS 120
Y+ K L IP +GKP P W D A DTR VSV + ++ L + + Q++D+
Sbjct: 13495 YLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTR-VSVESSAVNTTLIVYDCQKSDA 13553
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLG 179
G+Y + ++ TI I V+ +PG P IK +V + TL+W PP+D G + +
Sbjct: 13554 GKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITN 13613
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
Y ++K D+ + W T +T+ V+ L G Y FRV AEN+ G+ E
Sbjct: 13614 YILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE 13663
Score = 99.8 bits (247), Expect = 3e-21
Identities = 55/166 (33%), Positives = 83/166 (50%), Gaps = 1/166 (0%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQL 125
V + + +L+P G P+P A W L+T RV ++ + L I ++R+D G Y L
Sbjct: 6911 VPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTL 6970
Query: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185
+++ + ID+ VI RP P+ +K D+ S L W PP D G + L GY V+K
Sbjct: 6971 KLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR 7030
Query: 186 DTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
+ W V++ V DL+ G Y F+V A N+CG E A
Sbjct: 7031 EVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076
Score = 99.8 bits (247), Expect = 3e-21
Identities = 62/201 (30%), Positives = 99/201 (49%), Gaps = 6/201 (2%)
Query: 35 GAGSPTPQLLPPIE----EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G P LLP + E P+I + T + G + + IP GKP P+ + D
Sbjct: 19957 GLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRD 20016
Query: 91 GCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
G L T R + ++ + ++E+ AD+GRY++ A I+I+V++RPGPP
Sbjct: 20017 GVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPP 20076
Query: 150 QS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
+ + D+ S TL+W PP+ G + + Y + K +T + +W V RT V
Sbjct: 20077 TGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMK 20136
Query: 209 LIIGNSYAFRVFAENQCGLSE 229
L G Y FR+ AEN+ G+S+
Sbjct: 20137 LTTGEEYQFRIKAENRFGISD 20157
Score = 99.4 bits (246), Expect = 4e-21
Identities = 61/234 (26%), Positives = 106/234 (45%), Gaps = 19/234 (8%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNL 73
+ +VK + A P + G+ + I+E P++++ + + K G + +
Sbjct: 9281 RFRVKAVNEAGESEPSDTTGEIPATD-------IQEEPEVFIDIGAQDCLVCKAGSQIRI 9333
Query: 74 LIPFQGKPKPQAIWTHDGCALDTRRVSVRN---------GEQDSILFIREAQRADSGRYQ 124
+G+P P++ W DG A + V + E S++ I E +R+ +G+Y
Sbjct: 9334 PAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYS 9393
Query: 125 LRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK 184
+ + + TA + V++ PGPP+ +K+ D+ S L W P D G + GY ++K
Sbjct: 9394 ITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEK 9453
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS---ETAPITT 235
W V T+ +V DL+ Y FRV AEN+ G+ ET TT
Sbjct: 9454 RTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTT 9507
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/190 (32%), Positives = 92/190 (48%), Gaps = 5/190 (2%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSI- 109
P+I L A++ K G V L GKP P W DG L ++ Q ++
Sbjct: 12796 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAE-GIKMAMQRNLC 12854
Query: 110 -LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTP 168
L + R DSG Y + + +ATI + V+++PGPP S+K+ ++ A L W P
Sbjct: 12855 TLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEP 12914
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P + G + + Y V K +T W V TSC V LI G+ Y FR+ AEN+ G+
Sbjct: 12915 PLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVG 12974
Query: 229 ETAPITTDLA 238
+ P+ T+ A
Sbjct: 12975 D--PVFTEPA 12982
Score = 98.6 bits (244), Expect = 8e-21
Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQD 107
E PKI + + T I K G+ L G+P P W+ DG L+ T ++ ++ +
Sbjct: 14960 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS 15019
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEW 166
+ L +++ R DSG Y L G A ++ V++RPGPP+ + + +V L W
Sbjct: 15020 TNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCVLSW 15079
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
PP D G + Y VQK +T W V T V+ L+ GN Y FRV A N+ G
Sbjct: 15080 FPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYG 15139
Query: 227 LSE 229
+ E
Sbjct: 15140 VGE 15142
Score = 98.6 bits (244), Expect = 8e-21
Identities = 62/225 (27%), Positives = 108/225 (48%), Gaps = 12/225 (5%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P+I + + T + G++ + GKP P W L +T R+ +++ + +
Sbjct: 16044 PRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATS 16103
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L +++A R DSG Y L+ + E + T+++ V++RPGPP+ + + V TL W P
Sbjct: 16104 LSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKP 16163
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
P G + ++ Y V++ +T +W V + SC V+ L+ GN Y FR+ A N+ G+
Sbjct: 16164 PLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 16223
Query: 229 ETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTV 273
E P+ ++ V F D +AP+ T D V
Sbjct: 16224 E--PLESE--------PVVAKNPFVVPDAPKAPEVTTVTKDSMIV 16258
Score = 98.2 bits (243), Expect = 1e-20
Identities = 60/200 (30%), Positives = 97/200 (48%), Gaps = 2/200 (1%)
Query: 29 QASPGQGAGSPTPQLLPPIE--EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAI 86
Q G G + + + P E E P+I L ++R+ I + G + L +G+P P+
Sbjct: 12083 QNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVT 12142
Query: 87 WTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERP 146
W G R+ V + + L I + R DSG+Y L + E +++ V++ P
Sbjct: 12143 WRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTP 12202
Query: 147 GPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIV 206
GP +K+ DV S + W PP++ G + + Y V+K + W TV +TS V
Sbjct: 12203 GPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFHV 12262
Query: 207 SDLIIGNSYAFRVFAENQCG 226
++L+ GN Y FRV A N+ G
Sbjct: 12263 TNLVPGNEYYFRVTAVNEYG 12282
Score = 97.8 bits (242), Expect = 1e-20
Identities = 60/205 (29%), Positives = 102/205 (49%), Gaps = 5/205 (2%)
Query: 33 GQGAGSPTPQLLPPIE--EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
G G + P + P + E P++ L LR+ + + G + + IPF+G+P P+ W+ +
Sbjct: 17505 GLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSRE 17564
Query: 91 GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150
T +V + G + L I R D+G+Y L+++ +A + + V++ PGPPQ
Sbjct: 17565 EGEF-TDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQ 17623
Query: 151 SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210
++ + +V SA L W PP G + Y + K ++ + V +TS V +L
Sbjct: 17624 NLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLT 17683
Query: 211 IGNSYAFRVFAENQCGLSETAPITT 235
G Y FRV AEN+ G+ P+ T
Sbjct: 17684 EGAIYYFRVMAENEFGVG--VPVET 17706
Score = 97.8 bits (242), Expect = 1e-20
Identities = 56/179 (31%), Positives = 86/179 (48%), Gaps = 1/179 (0%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
P++ + +QT++ + G ++ L I +QG+P P A+W+ L R + + S L
Sbjct: 21858 PELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLR-ADIHTTDSFSTL 21916
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQ 170
+ R D+G+Y L V+ + T + V++ PGPP I DV SATL W P
Sbjct: 21917 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPL 21976
Query: 171 DTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
G + Y V+K + W + E R V+DL G Y FRV A N+ G+ E
Sbjct: 21977 LDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGE 22035
Score = 97.4 bits (241), Expect = 2e-20
Identities = 60/179 (33%), Positives = 91/179 (50%), Gaps = 2/179 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P I L ++T G V L+IP G+P P A W G L ++ RV+V + +
Sbjct: 23239 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23298
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTP 168
L IRE D+G Y L ++ + TI ++++++PGPP IK+ ++ S T+ W P
Sbjct: 23299 LTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEP 23358
Query: 169 PQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
P+ G L GY V++ D W V E R++ + L GN Y FRV A N+ G+
Sbjct: 23359 PELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGI 23417
Score = 96.7 bits (239), Expect = 3e-20
Identities = 55/190 (28%), Positives = 94/190 (49%), Gaps = 5/190 (2%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQD 107
E P+I + R T + G+T L GKP P W ++ + R ++N +
Sbjct: 17124 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17183
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEW 166
++L +++A R D G+Y LR + +++ V++RPGPP+ +++ V +L W
Sbjct: 17184 ALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTW 17243
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
+PP G + + Y V+K +T W V S V+ L+ GN Y FR+ A N+ G
Sbjct: 17244 SPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYG 17303
Query: 227 LS---ETAPI 233
+ E+AP+
Sbjct: 17304 VGEPLESAPV 17313
Score = 94.7 bits (234), Expect = 1e-19
Identities = 62/198 (31%), Positives = 92/198 (46%), Gaps = 3/198 (1%)
Query: 30 ASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH 89
A A P P L+ E P++ L + + KVGDT+ L +G P P+ W
Sbjct: 10698 AGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKK 10757
Query: 90 DGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGP 148
+ T+ R+ V S L IR A D G Y L V+ T ++ +LV+++PGP
Sbjct: 10758 EDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGP 10815
Query: 149 PQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
P+ +++ ++ S L W P D G + + Y V++ D S W + + S
Sbjct: 10816 PRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKH 10875
Query: 209 LIIGNSYAFRVFAENQCG 226
L GN Y FRV AENQ G
Sbjct: 10876 LNEGNQYLFRVAAENQYG 10893
Score = 93.6 bits (231), Expect = 2e-19
Identities = 55/190 (28%), Positives = 91/190 (47%), Gaps = 6/190 (3%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALD--TRRVSVRNGEQDS 108
P L + + G+T L +GKP P +W+ DG L+ R+ +++ Q +
Sbjct: 18208 PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKT 18267
Query: 109 ILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWT 167
L +++ R D G+Y L++ G + I + V++RPGPP+ +K+ V L W
Sbjct: 18268 TLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWN 18327
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
PP G + Y ++K +T W V + V+ L+ GN Y FRV A N+ G+
Sbjct: 18328 PPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18387
Query: 228 S---ETAPIT 234
E+ P+T
Sbjct: 18388 GEPLESGPVT 18397
Score = 93.6 bits (231), Expect = 2e-19
Identities = 55/187 (29%), Positives = 94/187 (50%), Gaps = 3/187 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQD 107
E P+I L LR+ + + T+ L + +G+P+P+ W +G D ++ V +
Sbjct: 18606 EPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSF-- 18663
Query: 108 SILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWT 167
++L I R DSGRY L ++ TA +++ V++ P P ++ + +V S TL W
Sbjct: 18664 TMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWE 18723
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
PP G + Y V+K +T + T+ + +T+ + +L G SY FRV A N+ G+
Sbjct: 18724 PPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783
Query: 228 SETAPIT 234
A T
Sbjct: 18784 GLPAETT 18790
Score = 93.6 bits (231), Expect = 2e-19
Identities = 64/205 (31%), Positives = 100/205 (48%), Gaps = 7/205 (3%)
Query: 45 PPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRN 103
P IE P L Q K G + +P G+P P+ W + L +T RVS+
Sbjct: 22144 PQIE--PTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITT 22201
Query: 104 GEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSA 162
+ + L ++++ R DSGRY L ++ T ++ ++VI RPGP I++ V S
Sbjct: 22202 TKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESC 22261
Query: 163 TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAE 222
L W P+D G T + Y V+K ++ + W V RT V+ L Y+FRV +E
Sbjct: 22262 VLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSE 22321
Query: 223 NQCGLS---ETAPITTDLAHIQKAA 244
N+ G+S E+API + + +A
Sbjct: 22322 NRFGVSKPLESAPIIAEHPFVPPSA 22346
Score = 93.2 bits (230), Expect = 3e-19
Identities = 66/236 (27%), Positives = 103/236 (43%), Gaps = 11/236 (4%)
Query: 5 TAPEVAAGS--KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQT 62
T E+ G+ KL+V + A PP G P + +E P + L +++
Sbjct: 8565 TVKEIREGADYKLRVSAVNAAGEGPP--------GETQPVTVAEPQEPPAVELDVSVKGG 8616
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
G T+ + G+P P +WT + LD RV + N S L I++A R D GR
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGR 8676
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Y + A + V + PGP +K V L W+ P+D G + + G+ +
Sbjct: 8677 YVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 8736
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
++ D K W +E R+ C ++ L+ G Y FRV A+N+ G I LA
Sbjct: 8737 ERKDAKMHTWRQPIE-TERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILA 8791
Score = 93.2 bits (230), Expect = 3e-19
Identities = 57/200 (28%), Positives = 98/200 (49%), Gaps = 3/200 (1%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWT 88
+A G+ A P P ++ E P I L LR+ + G ++ L +P +G+P P+ W
Sbjct: 16421 KAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWG 16480
Query: 89 H-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPG 147
DG D + V + +L R DSG+Y L ++ +A + + V++ P
Sbjct: 16481 KVDGEIRDAAIIDVTSSFTSLVL--DNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPS 16538
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVS 207
PP ++K+ ++ S ++ W PP G + + Y V+K + + V+ + H+ S +
Sbjct: 16539 PPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKID 16598
Query: 208 DLIIGNSYAFRVFAENQCGL 227
L G SY FRV AEN+ G+
Sbjct: 16599 QLQEGCSYYFRVTAENEYGI 16618
Score = 91.7 bits (226), Expect = 9e-19
Identities = 57/183 (31%), Positives = 88/183 (48%), Gaps = 2/183 (1%)
Query: 49 EHPKIWLPRALRQTYIRKVGDTVNL-LIPFQGKPKPQAIWTHDGCALDTRRVS-VRNGEQ 106
E P I L ++ K GDT+ L I GKP P++ W+ G + ++ + +
Sbjct: 13877 EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT 13936
Query: 107 DSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEW 166
S+L I+ A R D+G Y + + + V++ PGPP +++ +V ATL W
Sbjct: 13937 SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTW 13996
Query: 167 TPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
TPP + G + + Y ++K +T LW V E + + LI GN Y FRV A N G
Sbjct: 13997 TPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG 14056
Query: 227 LSE 229
E
Sbjct: 14057 KGE 14059
Score = 90.5 bits (223), Expect = 2e-18
Identities = 69/223 (30%), Positives = 96/223 (43%), Gaps = 7/223 (3%)
Query: 12 GSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRA-LRQTY----IRK 66
G + V+ + + Q AG P+ P+ + LP LR Y I K
Sbjct: 14522 GLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAK 14581
Query: 67 VGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
GD + + IP G+PKP W D T+RV+ +IL I E R+DSG Y L
Sbjct: 14582 AGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 14641
Query: 126 RVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK 184
+ E I I V + PGPP IK +V T W PP++ G + Y V+
Sbjct: 14642 TARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEM 14701
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
T S W + RT+ + L G Y FRV A+N+ G+
Sbjct: 14702 RQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGV 14744
Score = 90.1 bits (222), Expect = 3e-18
Identities = 56/191 (29%), Positives = 92/191 (48%), Gaps = 2/191 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSI 109
P++ L R +VG T+ +L +G+P+P WT +G L +RV +
Sbjct: 11409 PEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE 11468
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPP 169
L I+EA RAD G+Y + + A + + V++RPGP Q++K+ +V + T+ W P
Sbjct: 11469 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENP 11528
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
D G + + + V+ W V + I ++L+ N Y FRV AEN+ G+
Sbjct: 11529 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGVGP 11587
Query: 230 TAPITTDLAHI 240
T T + I
Sbjct: 11588 TIETKTPILAI 11598
Score = 89.7 bits (221), Expect = 3e-18
Identities = 52/173 (30%), Positives = 85/173 (49%), Gaps = 4/173 (2%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGC-ALDTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+VG+ L + GKPKP+ W D L+ R ++ L +A+R+DSG+Y
Sbjct: 10334 RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYC 10393
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ V+ + V++RPGPP + +V + W PP D G + + Y ++
Sbjct: 10394 VVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIE 10453
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTD 236
K + +W V +T+C VS L+ G Y FR+ AEN G+S+ P+ +D
Sbjct: 10454 KKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISD--PLVSD 10504
Score = 89.7 bits (221), Expect = 3e-18
Identities = 61/227 (26%), Positives = 105/227 (46%), Gaps = 10/227 (4%)
Query: 5 TAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIE--EHPKIWLPRALRQT 62
T P++ G K + A+ G S + + P+E E P + L L++T
Sbjct: 22906 TVPDLKMGQKYSFRVAAVN-------VKGMSEYSESIAEIEPVERIEIPDLELADDLKKT 22958
Query: 63 YIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGR 122
+ G ++ L++ G+P P W+ G L +R + + E S+L + + R D+G+
Sbjct: 22959 VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIVDKVNRYDAGK 23017
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
Y + + + +AT+ + V + PGP S+K+ +V S T+ W P G + Y V
Sbjct: 23018 YTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIV 23077
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+K + + TV +T +S L+ G Y FRV EN G+ E
Sbjct: 23078 EKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGE 23124
Score = 89.4 bits (220), Expect = 5e-18
Identities = 51/201 (25%), Positives = 96/201 (47%), Gaps = 2/201 (0%)
Query: 31 SPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90
S + + S P ++ E P++ + R + K G+ + + G+P P W D
Sbjct: 19270 SVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKD 19329
Query: 91 GCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPP 149
G ++ R R + + + ++L +++ R D+G+Y L ++ + ++ V+++PGPP
Sbjct: 19330 GIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPP 19389
Query: 150 QS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD 208
+++ + +L W PQ+ G + Y V+K +T W TSC V+
Sbjct: 19390 AGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTK 19449
Query: 209 LIIGNSYAFRVFAENQCGLSE 229
L+ GN Y FRV N+ G+ E
Sbjct: 19450 LLKGNEYIFRVTGVNKYGVGE 19470
Score = 87.8 bits (216), Expect = 1e-17
Identities = 51/163 (31%), Positives = 86/163 (52%), Gaps = 1/163 (0%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLR 126
G+ +++ +PF+ P P W DG + R++++N + L + ++ RAD+G Y +
Sbjct: 7904 GEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTIT 7963
Query: 127 VQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKAD 186
++ ATA+I++ VI PGP + IK D+ S L W PP+ G T +L Y +++ +
Sbjct: 7964 LENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERRE 8023
Query: 187 TKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ V+ ++ S V DLI Y FRV A N+ G E
Sbjct: 8024 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGE 8066
Score = 86.3 bits (212), Expect = 4e-17
Identities = 54/187 (28%), Positives = 92/187 (49%), Gaps = 8/187 (4%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
PKI + Q + VG + +++P+ PK +A W + L T+ + EQ S
Sbjct: 6503 PKI---KTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDT-TAEQTSFR 6558
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQ 170
+ EA++ D GRY++ +Q +A I++ VI+ PGP +++++ + + +L W P
Sbjct: 6559 IL-EAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPL 6617
Query: 171 DTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGN-SYAFRVFAENQCGLSE 229
G + ++GY V++ D K W + V+ L G Y FRV A N+ G E
Sbjct: 6618 TDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGE 6677
Query: 230 TAPITTD 236
P+ TD
Sbjct: 6678 --PVETD 6682
Score = 84.7 bits (208), Expect = 1e-16
Identities = 69/250 (27%), Positives = 111/250 (44%), Gaps = 13/250 (5%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
++G V+L +P++GKPKP W DG L ++ V E L I+ A++ G+Y
Sbjct: 21079 RIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21138
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ + I ++ + P P+ I+ ++ S L W P+D G + Y+++
Sbjct: 21139 VILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 21198
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
K +T W V RT+ V +L+ Y FRV AEN+ G+S+ + +A Q
Sbjct: 21199 KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFR 21258
Query: 244 ATVYKTKGFAQRDFSEAPKFT--QPLAD-CTTVTGYNTQLFCCVRASPRPKIIWLK-NKM 299
K S+ T P+ D + VTG++ V R I+W K N
Sbjct: 21259 IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFH------VEKKERNSILWQKVNTS 21312
Query: 300 DIQGNPKYRA 309
I G +YRA
Sbjct: 21313 PISGR-EYRA 21321
Score = 82.8 bits (203), Expect = 4e-16
Identities = 56/206 (27%), Positives = 90/206 (43%), Gaps = 15/206 (7%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-TVLEHYHRT 202
++P P ++++ + S TL+W P+ G +LGY V+ + W + E
Sbjct: 23932 DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDK 23991
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+ L+ Y FRVFAEN+ GLS ++ A KTK + EAP
Sbjct: 23992 QFTIGGLLEATEYEFRVFAENETGLSRP----------RRTAMSIKTKLTS----GEAPG 24037
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ + D TT G QL C + P P I W + ++ + KY+ + +L +
Sbjct: 24038 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMT 24097
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRV 348
D G+YTC A N +GE ++
Sbjct: 24098 EEQEDEGVYTCIATNEVGEVETSSKL 24123
Score = 80.5 bits (197), Expect = 2e-15
Identities = 52/183 (28%), Positives = 93/183 (50%), Gaps = 8/183 (4%)
Query: 59 LRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQR 117
L++ Y VG T+ L + + G+P P W H L ++ +++ N E + L ++ QR
Sbjct: 24137 LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQR 24196
Query: 118 -ADSGRYQLRVQLGGLEAT--ATIDILVIERPGPPQSIKLVD-VWGFSATLEWTPPQDTG 173
+G+Y +VQL + T A +D+ + ++P P +++ + SA + W PP D G
Sbjct: 24197 KTHAGKY--KVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDG 24254
Query: 174 NTALLGYTVQKADTKSGL-WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAP 232
+ + Y V+K + K G W V T+C + +L Y FRV A+N G+S+
Sbjct: 24255 GSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLE 24314
Query: 233 ITT 235
+++
Sbjct: 24315 VSS 24317
Score = 80.1 bits (196), Expect = 3e-15
Identities = 65/221 (29%), Positives = 96/221 (43%), Gaps = 7/221 (3%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKV--GDTV 71
+L + + DA Q GS + +E KI LP+ L G+ V
Sbjct: 24489 QLIIASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVV 24548
Query: 72 NLLIPFQGKPKPQAIWTHDGCALDTR---RVSVRNGEQDSILFIREAQRADSGRYQLRVQ 128
++ IPF GKP P W +D +V V S++F +R D+G Y + +
Sbjct: 24549 SIKIPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAGFYVVCAK 24607
Query: 129 LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTK 188
T+++ V + P PP+ +K+ DV S L WT P G + + Y V+K T
Sbjct: 24608 NRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT 24667
Query: 189 SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ W V T V +L SY FRV AEN+ GLS+
Sbjct: 24668 AERWLRV-GQARETRYTVINLFGKTSYQFRVIAENKFGLSK 24707
Score = 79.0 bits (193), Expect = 6e-15
Identities = 63/231 (27%), Positives = 98/231 (42%), Gaps = 34/231 (14%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIR-KVGDTVNLLIPFQGKPKPQAIW 87
+A G P+ + PP + I P+ + +T + K GD + L G P P W
Sbjct: 8158 RAENAAGISEPS-RATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITW 8216
Query: 88 THDGCALD-----------------------------TRRVSVRNGEQ-DSILFIREAQR 117
D + T+R+S+ N ++ +S L +R++ R
Sbjct: 8217 IKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLR 8276
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTAL 177
D G Y ++V+ A A + V++ PGPP + D+ S +W PP D G + +
Sbjct: 8277 PDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEI 8336
Query: 178 LGYTVQKAD-TK-SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
+ YT++K D TK W V V+ LI G Y FRV AEN+ G
Sbjct: 8337 INYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG 8387
Score = 77.0 bits (188), Expect = 2e-14
Identities = 47/149 (31%), Positives = 74/149 (49%), Gaps = 1/149 (0%)
Query: 79 GKPKPQAIWTHDGCALDT-RRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATAT 137
GKP+P+ IWT LD +VS++ + + I+ R+DSG+Y L V+ +
Sbjct: 22576 GKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS 22635
Query: 138 IDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE 197
+ + V++ PGP + + V TL W+ PQ+ G + Y V++ +T W V
Sbjct: 22636 VMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEG 22695
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
S +V+ LI N Y FRV A N+ G
Sbjct: 22696 ECPTLSYVVTRLIKNNEYIFRVRAVNKYG 22724
Score = 75.5 bits (184), Expect = 7e-14
Identities = 53/193 (27%), Positives = 86/193 (44%), Gaps = 4/193 (2%)
Query: 64 IRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGR 122
I K G+++ + QG+P P+ W DG ++ R + + + + LF+R+A R G
Sbjct: 21472 IIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGV 21531
Query: 123 YQLRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYT 181
Y + + A A I + V + PG I+ ++ G TL W P + G + Y
Sbjct: 21532 YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYI 21591
Query: 182 VQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQ 241
++K +T W + + S LI GN Y FRV A N+ G+ P+ +D Q
Sbjct: 21592 IEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGR--PLDSDPVVAQ 21649
Query: 242 KAATVYKTKGFAQ 254
TV G +
Sbjct: 21650 IQYTVPDAPGIPE 21662
Score = 74.7 bits (182), Expect = 1e-13
Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 2/178 (1%)
Query: 51 PKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSIL 110
P + L ++R + G + ++ GKP P W + L + ++ S +
Sbjct: 10025 PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLP-QEATIETTAISSSM 10083
Query: 111 FIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLV-DVWGFSATLEWTPP 169
I+ QR+ G Y L + E TI + V++ PGP + L ++ S L W P
Sbjct: 10084 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10143
Query: 170 QDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
+D G + + Y ++K ++ W V R + V LI G +Y FR+ AEN G+
Sbjct: 10144 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGM 10201
Score = 74.3 bits (181), Expect = 2e-13
Identities = 56/212 (26%), Positives = 86/212 (40%), Gaps = 16/212 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A + ERP PP I L+DV S +L W P+ G + +LGY V+ S
Sbjct: 15537 GLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSD 15596
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W T T ++ LI G Y+FRV A+N+ G+S+ ++ +
Sbjct: 15597 KWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPV------------- 15642
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
+D P F T + G + ++ P P + W K+ + ++ + A
Sbjct: 15643 --IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAE 15700
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
+ L I+ D G Y K N GEA
Sbjct: 15701 STENNSLLTIKDACREDVGHYVVKLTNSAGEA 15732
Score = 74.3 bits (181), Expect = 2e-13
Identities = 55/216 (25%), Positives = 87/216 (40%), Gaps = 20/216 (9%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEH 198
+L I+ PP+++++ D+ S +L W P G + + GY V++ D G W +
Sbjct: 20265 VLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTN 20324
Query: 199 YHRTSCIVSDLIIGNSYAFRVFAENQCG-LSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
T I+S L + Y FRVFA N G +S + + + I D
Sbjct: 20325 VTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI---------------DS 20369
Query: 258 SEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
P PL V G + +L + P P I W K+ ++Q N
Sbjct: 20370 YGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTD 20429
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ S+ I+ + G Y K N +G AS RV +
Sbjct: 20430 LASILIKDADRLNSGCYELKLRNAMGSASATIRVQI 20465
Score = 73.9 bits (180), Expect = 2e-13
Identities = 56/226 (24%), Positives = 95/226 (42%), Gaps = 22/226 (9%)
Query: 14 KLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNL 73
+ +VK + A P A+ G P + P I+ L++ + G VN+
Sbjct: 9591 EFRVKAVNAAGVSKPSATVGP-CDCQRPDMPPSID----------LKEFMEVEEGTNVNI 9639
Query: 74 LIPFQGKPKPQAIW---------THDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+ +G P P W + DT V+ + L I +++R+D+G Y
Sbjct: 9640 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTH-VNKLVVDDTCTLVIPQSRRSDTGLYT 9698
Query: 125 LRVQLGGLEATATIDILVIERPGPPQS-IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
+ A+ + + V+ RPGPP IK V TL W PP+D G + + Y ++
Sbjct: 9699 ITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIE 9758
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
K + W V + + L+ G+ Y FR+ A+N+ G+ E
Sbjct: 9759 KREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9804
Score = 73.6 bits (179), Expect = 3e-13
Identities = 58/209 (27%), Positives = 91/209 (43%), Gaps = 20/209 (9%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH--YHRTS 203
PGPP + ++VD S +L WT P G T ++GY ++ + + W+ V + T
Sbjct: 22845 PGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTE 22904
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V DL +G Y+FRV A N G+SE + ++ +++ + ++ K
Sbjct: 22905 FTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIE-------IPDLELADDLKK 22957
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL--THLGICSLEIR 321
T T G + +L V P P I W K +D+ RA+ T L +
Sbjct: 22958 T-----VTIRAGASLRLMVSVSGRPPPVITWSKQGIDLAS----RAIIDTTESYSLLIVD 23008
Query: 322 KPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
K +D G YT +A N G+ S V V
Sbjct: 23009 KVNRYDAGKYTIEAENQSGKKSATVLVKV 23037
Score = 72.8 bits (177), Expect = 4e-13
Identities = 58/208 (27%), Positives = 87/208 (41%), Gaps = 18/208 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP+++K D S L W PP++ G + + GY V++ S W E T
Sbjct: 7091 PDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKME 7150
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF-- 263
V+ L G YA+RV A N+ G S+ + T ++ + D EAP+
Sbjct: 7151 VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAV---------------DTQEAPEIFL 7195
Query: 264 -TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ LA T G +L V P PKI W K M ++ + + ++ I
Sbjct: 7196 DVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVD 7255
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y +AVN G A+ V+V
Sbjct: 7256 SKRSDTGTYIIEAVNVCGRATAVVEVNV 7283
Score = 71.6 bits (174), Expect = 1e-12
Identities = 49/218 (22%), Positives = 86/218 (39%), Gaps = 16/218 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A I V E P PP I + DV S +L WT P+ G + ++ Y V+ S
Sbjct: 16619 GLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSE 16678
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W + ++++L G Y FRV A N+ G S+ + +
Sbjct: 16679 KW-SECARVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPI------------- 16724
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
+D P + + G + ++ + P+P I W K+ + ++ +
Sbjct: 16725 --VAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVT 16782
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
L + +L I++ DGG Y N +G+ + +
Sbjct: 16783 DSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEI 16820
Score = 69.7 bits (169), Expect = 4e-12
Identities = 59/213 (27%), Positives = 82/213 (38%), Gaps = 16/213 (7%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRT 202
E+PG P + V S + W PP G + Y ++K + K W +V E T
Sbjct: 24326 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24385
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
V +LI G Y FRV EN G SE + I+ + +AP
Sbjct: 24386 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPI-------------QAPH 24432
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHL-GICSLEI 320
F + L + N L C V P+P + W + K I KYR G L I
Sbjct: 24433 FKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLII 24492
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D +Y +A N G S ++V+VP
Sbjct: 24493 ASVTDDDATVYQVRATNQGGSVSGTASLEVEVP 24525
Score = 69.3 bits (168), Expect = 5e-12
Identities = 59/215 (27%), Positives = 88/215 (40%), Gaps = 17/215 (7%)
Query: 137 TID-ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
T+D + E P PP + L DV SA+L W P+ G + +LGY V+ + W V
Sbjct: 17706 TVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIV 17765
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR 255
E + +V+ L G Y FRV A N+ G S+ P + I K T+
Sbjct: 17766 AES-KVCNAVVTGLSSGQEYQFRVKAYNEKGKSD--PRVLGVPVIAKDLTI--------- 17813
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
P P + G + ++ V PRP I W+K+ ++ +
Sbjct: 17814 ----QPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATS 17869
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I++ D G YT A N G A+ + V V
Sbjct: 17870 TVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIV 17904
Score = 68.9 bits (167), Expect = 6e-12
Identities = 60/212 (28%), Positives = 85/212 (40%), Gaps = 23/212 (10%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT---VLEHY 199
I +P PP + + +D S L W PP+ G + +LGY V+ W E
Sbjct: 10613 IAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESC 10672
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
T V+ L G +Y FRV A N G S D AH+ + V +D E
Sbjct: 10673 PETKYKVTGLRDGQTYKFRVLAVNAAGES-------DPAHVPEPVLV--------KDRLE 10717
Query: 260 APKF---TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC 316
P+ + G +L ++ P PK+ W K D + +T +G
Sbjct: 10718 PPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARI-DVTPVG-S 10775
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
LEIR DGGIY+ NP G +V +V
Sbjct: 10776 KLEIRNAAHEDGGIYSLTVENPAGSKTVSVKV 10807
Score = 67.8 bits (164), Expect = 1e-11
Identities = 76/309 (24%), Positives = 123/309 (39%), Gaps = 41/309 (13%)
Query: 48 EEHPKIWLPRALRQTYIR-KVGDTVNLLIPFQGKPKPQAIWTHDGC-------ALDTRRV 99
E P I L ++R I+ K G+ V++ G P P+ W+ + AL +
Sbjct: 8895 EVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKE 8954
Query: 100 SVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWG 159
V E + L I +A R D G Y + + + V +RP PP+++ + D+
Sbjct: 8955 EVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKA 9014
Query: 160 FSATLEWTPPQDTGNTALLGYTVQKADT--KSGLWFTVLEHYHRTSCIVSDLIIGNSYAF 217
S L W P D G + + Y + K D K W V + LI Y F
Sbjct: 9015 ESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEF 9074
Query: 218 RVFAENQCGLSETAPITTDLAHIQKAATV----YKTKGFAQRDFSEAPKFTQPLAD-CTT 272
RV A N+ G+S+ +D IQ + K K A+ S +T PL + +
Sbjct: 9075 RVRAVNKYGISDEC--KSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSP 9132
Query: 273 VTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKY-----RALTHLGICSLEIRKPGPFD 327
+TGY WL+ + +G+P + +T +G+ +E P +
Sbjct: 9133 ITGY-----------------WLEKRE--EGSPYWSRVSRAPITKVGLKGVEFNVPRLLE 9173
Query: 328 GGIYTCKAV 336
G Y +A+
Sbjct: 9174 GVKYQFRAM 9182
Score = 67.8 bits (164), Expect = 1e-11
Identities = 59/216 (27%), Positives = 84/216 (38%), Gaps = 25/216 (11%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF------ 193
+LV E P P +++VDV + TL W P G + L GY ++ + W
Sbjct: 23132 VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLK 23191
Query: 194 -TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGF 252
TVLEH V+ L G Y FR+ A+N+ G+SE T A TV +
Sbjct: 23192 PTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETVT-------AVTVQDLRVL 23238
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTH 312
D S T P G +L + P P W ++ + + TH
Sbjct: 23239 PTIDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETH 23293
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRV 348
+ L IR+ D G YT + N G S +V
Sbjct: 23294 TKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23329
Score = 67.0 bits (162), Expect = 2e-11
Identities = 57/213 (26%), Positives = 88/213 (41%), Gaps = 22/213 (10%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHR 201
IERP PP ++ D S L+W PP G + +LGY +++ + W ++
Sbjct: 6792 IERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPE 6851
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETA----PITTDLAHIQKAATVYKTKGFAQRDF 257
+ V+ L GN Y +RV AEN+ G+S+ + P+T D A ++ + A +D
Sbjct: 6852 LTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDL-----SAFKDG 6906
Query: 258 SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
E P+ TGY PRP W ++ + + T
Sbjct: 6907 LEV-IVPNPITILVPSTGY-----------PRPTATWCFGDKVLETGDRVKMKTLSAYAE 6954
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I D GIYT K N + S + V+V
Sbjct: 6955 LVISPSERSDKGIYTLKLENRVKTISGEIDVNV 6987
Score = 67.0 bits (162), Expect = 2e-11
Identities = 52/220 (23%), Positives = 82/220 (37%), Gaps = 16/220 (7%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL A T + V E P PP + LVDV +AT++W P+ G + + GY V+ S
Sbjct: 18784 GLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSE 18843
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
W T + +S L G Y FRV A N+ G S+ + +
Sbjct: 18844 KWSTCTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV------------- 18889
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
RD P P ++ + P+ + W K+ ++ +
Sbjct: 18890 --IARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVS 18947
Query: 311 THLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + SL I++ D G Y N G +V + V
Sbjct: 18948 SSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIV 18987
Score = 66.6 bits (161), Expect = 3e-11
Identities = 59/215 (27%), Positives = 88/215 (40%), Gaps = 21/215 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE--HYH 200
I+ PGPP I++ D S TL W+ P G +A+ GY V+ + W TV
Sbjct: 20667 IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20726
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
T +VS+L G +Y FRV A N G E + + +D EA
Sbjct: 20727 TTEYVVSNLKPGVNYYFRVSAVNCAGQGE---------------PIEMNEPVQAKDILEA 20771
Query: 261 PKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P+ +A T+V G + Q+ + P P + W K++ ++ + +Y
Sbjct: 20772 PEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSL 20831
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
L I + D G Y N +GE V VKV
Sbjct: 20832 LTIPQVTRNDTGKYILTIENGVGEPK-SSTVSVKV 20865
Score = 65.9 bits (159), Expect = 5e-11
Identities = 54/211 (25%), Positives = 81/211 (38%), Gaps = 19/211 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHR 201
+ PGPP +K+ D + +LEW+ P G ++GY ++ G W V E +
Sbjct: 21754 VNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVK 21813
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
T V+DL G Y FRV A N G ++ +T + + + + D
Sbjct: 21814 TRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLTA-------PELDIDANF 21866
Query: 262 KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL--GICSLE 319
K T + G + +LF + P P +W K N RA H +L
Sbjct: 21867 KQTHVVR-----AGASIRLFIAYQGRPTPTAVWSKP----DSNLSLRADIHTTDSFSTLT 21917
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ D G YT N G S+ V V
Sbjct: 21918 VENCNRNDAGKYTLTVENNSGSKSITFTVKV 21948
Score = 63.9 bits (154), Expect = 2e-10
Identities = 57/217 (26%), Positives = 87/217 (40%), Gaps = 21/217 (9%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY 199
++ ++ PP +++++ S TL WT P+ G L GY V+K D S W H
Sbjct: 13771 VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKA-NHV 13829
Query: 200 HRTSC--IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
+ C V+DL+ G Y FR+ A+N G +A T+ +D
Sbjct: 13830 NVPECAFTVTDLVEGGKYEFRIRAKNTAGAI--------------SAPSESTETIICKDE 13875
Query: 258 SEAPKFT--QPLADCTTVTGYNTQLF--CCVRASPRPKIIWLKNKMDIQGNPKYRALTHL 313
EAP + D T+ +T + + P PK W K DI+ + + +
Sbjct: 13876 YEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTP 13935
Query: 314 GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I+ D G YT A NP G +V V
Sbjct: 13936 TSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTV 13972
Score = 63.5 bits (153), Expect = 3e-10
Identities = 56/215 (26%), Positives = 88/215 (40%), Gaps = 26/215 (12%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW--FTVLEHYH 200
I +PGPP + K++D+ S L W+ P G + GY V+K D G W T +
Sbjct: 16338 IYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGIN 16397
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
+T+ V L+ + Y FR+ A N+ G+ E A + + +K EA
Sbjct: 16398 KTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL---------------EA 16442
Query: 261 PKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL--GI 315
P L + G + +LF ++ P P++ W K + G + A+ +
Sbjct: 16443 PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGK----VDGEIRDAAIIDVTSSF 16498
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
SL + +D G YT N G S V V
Sbjct: 16499 TSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRV 16533
Score = 63.2 bits (152), Expect = 3e-10
Identities = 66/274 (24%), Positives = 113/274 (41%), Gaps = 40/274 (14%)
Query: 101 VRNGEQDSILFIREAQRADSGR------------YQLRVQL---GGLEATA-----TIDI 140
V E++SIL+ + SGR YQ RV GL + + T+ +
Sbjct: 21296 VEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAV 21355
Query: 141 LVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYH 200
++ PG P I DV + TL+W PP G + ++GY+++K
Sbjct: 21356 SPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVS 21412
Query: 201 RTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
V+ L G+ Y FR+ A N G ++ +++ + T RD +
Sbjct: 21413 ECQYTVTGLSPGDRYEFRIIARNAVG---------TISPPSQSSGIIMT-----RDENVP 21458
Query: 261 P--KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P +F D + +G + ++ V+ P P++ W K+ ++I+ LG S
Sbjct: 21459 PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTS 21518
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L +R G+YT +A N G A + +V V+
Sbjct: 21519 LFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552
Score = 62.0 bits (149), Expect = 8e-10
Identities = 31/88 (35%), Positives = 48/88 (54%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP+ ++++++ +A L+WT P+ G + + Y V+K D + W TV T C
Sbjct: 7587 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCT 7646
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPI 233
V+ L G+ Y FRV AEN G S+ I
Sbjct: 7647 VTPLTEGSLYVFRVAAENAIGQSDYTEI 7674
Score = 61.2 bits (147), Expect = 1e-09
Identities = 56/213 (26%), Positives = 81/213 (38%), Gaps = 20/213 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRT 202
I+ PGPP + KL D +A L WT P G + +LGY V+ + W + +
Sbjct: 11304 IKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDELIR 11363
Query: 203 SCI--VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEA 260
C V LI GN Y FR+ A N G E + + +D
Sbjct: 11364 QCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL---------------AESVIAKDILHP 11408
Query: 261 PKFTQPLA--DCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS 317
P+ + D TV G ++ V+ P P I W K + + + L
Sbjct: 11409 PEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVE 11468
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L+I++ D G Y A N G A V+V
Sbjct: 11469 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNV 11501
Score = 60.8 bits (146), Expect = 2e-09
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 9/142 (6%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
+EA + D+ PGPP ++ + DV F +L W PP+ G + Y ++ D S
Sbjct: 6685 VEARSKYDV-----PGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIR 6739
Query: 192 WFTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGL---SETAPITTDLAHIQKAATVY 247
W T + S V+D++ G Y+FRV A+N+ G+ S P I++ +
Sbjct: 6740 WDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPV 6799
Query: 248 KTKGFAQRDFSEAPKFTQPLAD 269
Q S K+ PL D
Sbjct: 6800 NLTSSDQTQSSVQLKWEPPLKD 6821
Score = 59.7 bits (143), Expect = 4e-09
Identities = 61/221 (27%), Positives = 83/221 (37%), Gaps = 32/221 (14%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ------KADTKSGLW--FT 194
IE PGPP + ++VD S TL W P G ++GY V+ A G W
Sbjct: 11997 IEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEG-WKRCN 12055
Query: 195 VLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQ 254
R V+ L Y FRV A+NQ G+ A + +
Sbjct: 12056 AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAEL---------------KEAIKP 12100
Query: 255 RDFSEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
++ E P+ + V G +LF VR P PK+ W K +D N +
Sbjct: 12101 KEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGID---NVVRKGQV 12157
Query: 312 HL--GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L + L I D G Y+ VNP GE +V V V
Sbjct: 12158 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRV 12198
Score = 59.7 bits (143), Expect = 4e-09
Identities = 66/250 (26%), Positives = 94/250 (37%), Gaps = 30/250 (12%)
Query: 114 EAQRADSG-RYQLRVQ----LGGLEATATIDILVIERP-GPPQSIKLVDVWGFSATLEWT 167
+AQ + G Y+ RV +G +A+ + V P PP + + + V TL+WT
Sbjct: 16986 KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWT 17045
Query: 168 PPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
P G + + GY V+K D G W + T VS L Y FRV A+N G
Sbjct: 17046 KPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAG 17105
Query: 227 L-----SETAPITT-DLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQL 280
T PIT D + + S PKF + G +L
Sbjct: 17106 AISKPSDSTGPITAKDEVELPR--------------ISMDPKFRDTI---VVNAGETFRL 17148
Query: 281 FCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
V P P I WL+ +I+ + + L ++ DGG Y +A N G
Sbjct: 17149 EADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAG 17208
Query: 341 EASVDCRVDV 350
S V V
Sbjct: 17209 SKSFPVNVKV 17218
Score = 59.3 bits (142), Expect = 5e-09
Identities = 46/207 (22%), Positives = 76/207 (36%), Gaps = 17/207 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR--TS 203
P PP + + D + W PP+ G + ++GY V+ + W V +
Sbjct: 7788 PSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKF 7847
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
+ ++ Y RV A N G+SE + I+ ++ +D P
Sbjct: 7848 KVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENV---------------VAKDPDCKPTI 7892
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
D + G + RA P P + W K+ +++ + + LE+ K
Sbjct: 7893 DLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKS 7952
Query: 324 GPFDGGIYTCKAVNPLGEASVDCRVDV 350
D GIYT N LG A+ V V
Sbjct: 7953 VRADAGIYTITLENKLGSATASINVKV 7979
Score = 59.3 bits (142), Expect = 5e-09
Identities = 56/225 (24%), Positives = 88/225 (39%), Gaps = 30/225 (13%)
Query: 135 TATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT 194
T + I I+RPG P+++ + D L+W P G + L Y V++ S W
Sbjct: 11593 TPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWER 11652
Query: 195 VLE------HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYK 248
V + HY C+ + + Y FRV +N+ G S+ K
Sbjct: 11653 VHKGSIKETHYMVDRCVENQI-----YEFRVQTKNEGGESDWV----------------K 11691
Query: 249 TKGFAQRDFSEAPKFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNK--MDIQGNP 305
T+ ++ + P L+ TV G +L VR P P++ W K+K D+ +P
Sbjct: 11692 TEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSP 11751
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + T + K DGG Y A N G V+V
Sbjct: 11752 RVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNV 11796
Score = 59.3 bits (142), Expect = 5e-09
Identities = 49/210 (23%), Positives = 78/210 (37%), Gaps = 15/210 (7%)
Query: 133 EATATID-ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
E T T + + E P PP S+ ++D+ + +L W P+ G + + GY ++ S
Sbjct: 14454 EPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQ 14513
Query: 192 WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKG 251
W T + C+V +L G Y F+V A N G S + Q +G
Sbjct: 14514 W-THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRG 14572
Query: 252 FAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT 311
Q+ G N ++ V P+P + W K ++ + T
Sbjct: 14573 IYQK-------------LVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFET 14619
Query: 312 HLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
L I + D G Y A N +GE
Sbjct: 14620 TATSTILNINECVRSDSGPYPLTARNIVGE 14649
Score = 58.9 bits (141), Expect = 7e-09
Identities = 52/208 (25%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP + + V S TL+W P G + + GY V+K + G W + T V
Sbjct: 15944 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEV 16003
Query: 207 SDLIIGNSYAFRVFAENQCGL-SETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
+ L+ + Y FRV A N G+ SE + T RD + P+ +
Sbjct: 16004 TGLVEDHRYEFRVIARNAAGVFSEPSE---------------STGAITARDEVDPPRISM 16048
Query: 266 PLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
T+ G + ++ + P P I W+K ++ + + SL ++
Sbjct: 16049 DPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKD 16108
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y KA N GE SV V V
Sbjct: 16109 AVRVDSGNYILKAKNVAGERSVTVNVKV 16136
Score = 58.5 bits (140), Expect = 9e-09
Identities = 51/212 (24%), Positives = 77/212 (36%), Gaps = 35/212 (16%)
Query: 140 ILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY 199
I+ E+P PP+ + +VD SA L W P G + + GY ++ S W H
Sbjct: 22043 IVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHT 22101
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
+ + V L+ Y FRV A+N G SE + F+ E
Sbjct: 22102 KQLTFTVERLVEKTEYEFRVKAKNDAGYSE------------------PREAFSSVIIKE 22143
Query: 260 APKFTQPLADCTTVTGYNTQLFCC-----------VRASPRPKIIWLKNKMDIQGNPKYR 308
+P AD +TG QL C + P PK+ W +M ++ +
Sbjct: 22144 PQ--IEPTAD---LTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS 22198
Query: 309 ALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
T +L ++ D G Y N G
Sbjct: 22199 ITTTKDRTTLTVKDSMRGDSGRYFLTLENTAG 22230
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/218 (24%), Positives = 81/218 (37%), Gaps = 29/218 (13%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ-----KADTKSGLWFTVLEH-Y 199
P PP +K+ + + L W PP++ G + + Y V+ TK W +
Sbjct: 9515 PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDV 9574
Query: 200 HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSE 259
V DL+ G Y FRV A N G+S+ + T G +
Sbjct: 9575 EELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS----------------ATVGPCDCQRPD 9618
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-------NKMDIQGNPKYRALTH 312
P G N + ++ P P + W K NK + + L
Sbjct: 9619 MPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVV 9678
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
C+L I + D G+YT AVN LG AS + R++V
Sbjct: 9679 DDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9716
Score = 58.2 bits (139), Expect = 1e-08
Identities = 54/208 (25%), Positives = 80/208 (38%), Gaps = 20/208 (9%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P PP K+VD + T+ W P G + GYTV+ + W T ++ T
Sbjct: 19587 PSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYT 19646
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF-- 263
+S L G Y FRV + N+ G S+ +D + Q A ++ E P F
Sbjct: 19647 ISGLTTGAEYVFRVKSVNKVGASD----PSDSSDPQIA-----------KEREEEPLFDI 19691
Query: 264 -TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
++ G + + R P P ++W K D++ + T SL I
Sbjct: 19692 DSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLR--TRAYVDTTDSRTSLTIEN 19749
Query: 323 PGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G YT N L AS+ V V
Sbjct: 19750 ANRNDSGKYTLTIQNVLSAASLTLVVKV 19777
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/212 (21%), Positives = 86/212 (40%), Gaps = 17/212 (8%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
G+ A + + E+P PP+ + + + S +L W P+ G + ++ Y V+ +
Sbjct: 19863 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 19922
Query: 191 LWF--TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYK 248
W V + H +VS L + Y FRVFAENQ GLS+ + + ++
Sbjct: 19923 NWVKCAVAKSTHH---VVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEP--- 19976
Query: 249 TKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR 308
+ D P T + G N ++ + P PK+ ++ + ++ ++
Sbjct: 19977 ----PEIDMKNFPSHTVYVR-----AGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFN 20027
Query: 309 ALTHLGICSLEIRKPGPFDGGIYTCKAVNPLG 340
++ +++ D G Y A N G
Sbjct: 20028 TEITAENLTINLKESVTADAGRYEITAANSSG 20059
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/106 (33%), Positives = 56/106 (52%), Gaps = 10/106 (9%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L++T T+ P PP + D+ +AT+ WT P+ G + + GY +++ + +G
Sbjct: 11193 LDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYMERREV-TGK 11251
Query: 192 WFTVLEHYHRTSCI-----VSDLIIGNSYAFRVFAENQCGLSETAP 232
W V ++T V+ L GN+Y FRVFAEN GLS+ +P
Sbjct: 11252 WVRV----NKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSP 11293
Score = 57.8 bits (138), Expect = 1e-08
Identities = 55/208 (26%), Positives = 79/208 (37%), Gaps = 29/208 (13%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF-----TVLE 197
I+ PG P + + + TL+W P+ TG + Y V+K D +G W +LE
Sbjct: 14860 IDPPGKPVPLNITR---HTVTLKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILE 14916
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDF 257
+ S + D +Y FRV A+N G +D RD
Sbjct: 14917 NEFTVSGLTEDA----AYEFRVIAKNAAGAISPPSEPSD--------------AITCRDD 14958
Query: 258 SEAPKFTQPLADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
EAPK + TV G +L V P P + W K+ +++G K
Sbjct: 14959 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15018
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
+L + D G YT A NP G A
Sbjct: 15019 STNLVNKDSTRRDSGAYTLTATNPGGFA 15046
Score = 56.6 bits (135), Expect = 3e-08
Identities = 46/200 (23%), Positives = 78/200 (39%), Gaps = 17/200 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF--TVLEHYHRTS 203
PGPP + + D SA+L W P G + GY V+ W T T
Sbjct: 14176 PGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQ 14235
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
+V DL Y FR+ A N G+ E A + D+ +++ DF +
Sbjct: 14236 FVVPDLQTKEKYNFRISAINDAGVGEPA-VIPDVEIVEREMA---------PDFELDAEL 14285
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
+ L G + ++F ++ P P++ W K+ ++++ + L I +
Sbjct: 14286 RRTL---VVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTL--LIIPEC 14340
Query: 324 GPFDGGIYTCKAVNPLGEAS 343
+D G + NP G+ S
Sbjct: 14341 NRYDTGKFVMTIENPAGKKS 14360
Score = 55.8 bits (133), Expect = 6e-08
Identities = 29/83 (34%), Positives = 47/83 (56%), Gaps = 1/83 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTSC 204
PGPP+ ++ +V +AT+ W P D G + + GY V++ + KS W ++ C
Sbjct: 14075 PGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRC 14134
Query: 205 IVSDLIIGNSYAFRVFAENQCGL 227
V+ L G++Y FRV AEN+ G+
Sbjct: 14135 KVTGLQEGSTYEFRVSAENRAGI 14157
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/223 (25%), Positives = 88/223 (39%), Gaps = 22/223 (9%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
G T + E P P + + + D S L WT P G + + Y V++
Sbjct: 20951 GEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQ 21010
Query: 191 LWFTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKT 249
W +T I VS L + FRVFA+N+ GLS+ P+T +++ +
Sbjct: 21011 TWSHA--GISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD--PVTIGPITVKELIITPEV 21066
Query: 250 KGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA 309
D S+ P A T G+N L + P+P I WLK+ + ++ + R
Sbjct: 21067 ------DLSDIPG-----AQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRF 21115
Query: 310 LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
+L I+ GG YT N + CR+ V +
Sbjct: 21116 SKTENKITLSIKNAKKEHGGKYTVILDNAV------CRIAVPI 21152
Score = 54.7 bits (130), Expect = 1e-07
Identities = 40/159 (25%), Positives = 71/159 (44%), Gaps = 14/159 (8%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ--KADTKSGLWFTVLEHYHRTS 203
PGPP K+ D S +L W P G + ++GY V+ +AD+ + + + ++ +T
Sbjct: 13092 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13151
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V+ L+ Y FRV+A N+ G S+ + + H K + +G D +
Sbjct: 13152 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPD--KHYPKDILI-PPEGELDADLRKT--- 13205
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ 302
G +L+ V+ P PKI W K ++++
Sbjct: 13206 ------LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLR 13238
Score = 54.3 bits (129), Expect = 2e-07
Identities = 29/89 (32%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query: 146 PGPPQSI-KLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTS 203
P PP + +++DV S +L W+ P+D G + + GY +++ +T + W + T
Sbjct: 23832 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 23891
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAP 232
V+ L+ Y FR+ A+N GLSET+P
Sbjct: 23892 YTVTGLVPDAEYQFRIIAQNDVGLSETSP 23920
Score = 53.9 bits (128), Expect = 2e-07
Identities = 31/91 (34%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP+S+++ ++ S T+ W P G + ++GY V+K D +SG+ + T
Sbjct: 17322 PGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRD-RSGIRWIKCNKRRITDLR 17380
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
V+ L + Y FRV AEN G+ E +P T
Sbjct: 17381 LRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 17411
Score = 53.9 bits (128), Expect = 2e-07
Identities = 40/136 (29%), Positives = 53/136 (38%), Gaps = 3/136 (2%)
Query: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTG 275
AF+ E +SET +D + T KT+ A S P L D T +
Sbjct: 26313 AFKSIHEKVSKISETKK--SDQKTTESTVT-RKTEPKAPEPISSKPVIVTGLQDTTVSSD 26369
Query: 276 YNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
+ PRP IW K+ I KY+ G LEI K D G+YTC
Sbjct: 26370 SVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTV 26429
Query: 336 VNPLGEASVDCRVDVK 351
N G S C++ +K
Sbjct: 26430 KNSAGSVSSSCKLTIK 26445
Score = 53.5 bits (127), Expect = 3e-07
Identities = 33/102 (32%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
Query: 131 GLEATATIDILV---IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADT 187
G + +T IL+ I+ P PP + DV S L WT P+ G + Y ++ T
Sbjct: 7469 GKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKT 7528
Query: 188 KSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ W V E T ++ L+ G Y+FRV A N+ G SE
Sbjct: 7529 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESE 7570
Score = 52.8 bits (125), Expect = 5e-07
Identities = 27/92 (29%), Positives = 41/92 (44%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P L + T + G + L C + P P + W + I+ + ++ GI L I
Sbjct: 897 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
R+ D G +TC AVN G S C + V+V
Sbjct: 957 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/211 (25%), Positives = 80/211 (37%), Gaps = 24/211 (11%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
PG P++I + + TL+W P G + + GY V+K D G W + T
Sbjct: 18109 PGRPEAIVITRN---NVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEF 18165
Query: 205 IVSDLIIGNSYAFRVFAENQCG-LSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP-- 261
VS L+ Y FRV A N G SE + + RD +AP
Sbjct: 18166 TVSGLVEDQRYEFRVIARNAAGNFSEPSD---------------SSGAITARDEIDAPNA 18210
Query: 262 KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGN-PKYRALTHLGICSLE 319
D V G L +R P P ++W K+ +++ + + + +L
Sbjct: 18211 SLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLV 18270
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
++ DGG Y K N G S+ V V
Sbjct: 18271 VKDCIRTDGGQYILKLSNVGGTKSIPITVKV 18301
Score = 51.2 bits (121), Expect = 1e-06
Identities = 38/125 (30%), Positives = 58/125 (46%), Gaps = 9/125 (7%)
Query: 114 EAQRADSG-RYQLRVQLG-------GLEATATIDILVIERPGPPQSIKLVDVWGFSATLE 165
+A R +G YQ RV+ G+ + + + PGPP + ++ V S T+
Sbjct: 14722 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 14781
Query: 166 WTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD-LIIGNSYAFRVFAENQ 224
W P G + +LGY V++ + LW TV + + S L G +Y FRV AEN
Sbjct: 14782 WHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENM 14841
Query: 225 CGLSE 229
G S+
Sbjct: 14842 AGKSK 14846
Score = 50.8 bits (120), Expect = 2e-06
Identities = 55/235 (23%), Positives = 82/235 (34%), Gaps = 46/235 (19%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRTSC 204
P PP +++ + + T+ W PP G + ++GY ++K W EH +
Sbjct: 8083 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8142
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
L G Y FRV AEN G+SE + T + D +APK
Sbjct: 8143 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV---------------DPIDAPKVI 8187
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNK-MDIQGNPKYRALTHLGICSLEIRKP 323
G L + SP P I W+K++ + + K RA + E+++
Sbjct: 8188 L-RTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 8246
Query: 324 GPF----------------------------DGGIYTCKAVNPLGEASVDCRVDV 350
PF D G+Y K N G A C V V
Sbjct: 8247 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8301
Score = 50.8 bits (120), Expect = 2e-06
Identities = 55/221 (24%), Positives = 84/221 (38%), Gaps = 33/221 (14%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH---YHRT 202
PGPP ++ D S +L W PP G + + GY V+ + + W V E
Sbjct: 9208 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9267
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDL--AHIQKAATVYKTKGFAQRDFSEA 260
C+V +L Y FRV A N+ G SE + T ++ IQ+ V+ G
Sbjct: 9268 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIG--------- 9318
Query: 261 PKFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIW-----LKNKM-----DIQGNPKYRA 309
DC G ++ ++ P PK W K M DI + +
Sbjct: 9319 ------AQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLET 9372
Query: 310 LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + + K G Y+ A N G+ + +CRV V
Sbjct: 9373 AENSSVIIIPECKRS--HTGKYSITAKNKAGQKTANCRVKV 9411
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/211 (27%), Positives = 84/211 (39%), Gaps = 20/211 (9%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR- 201
I PGPP K+ D SA LEW+PP G + + GY V+ + W + R
Sbjct: 9922 IAPPGPPFP-KVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 9980
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
T +V+ L G Y FRV A N G+ E + TD+ ++ R S
Sbjct: 9981 TKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEV-TDVIEMK------------DRLVSPDL 10027
Query: 262 KFTQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI-CSLE 319
+ + D V G ++ V P P + W N+ + P+ + I S+
Sbjct: 10028 QLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTL---PQEATIETTAISSSMV 10084
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I+ G+Y+ A N GE VDV
Sbjct: 10085 IKNCQRSHQGVYSLLAKNEAGERKKTIIVDV 10115
Score = 50.8 bits (120), Expect = 2e-06
Identities = 52/206 (25%), Positives = 77/206 (37%), Gaps = 16/206 (7%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PGPP+ + VDV +L W P G + + GY V+ + + W + C+
Sbjct: 10913 PGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECV 10971
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
V+ L G +Y FRV AEN GL P TT Q ++ + +
Sbjct: 10972 VTGLQQGKTYRFRVKAENIVGLG--LPDTTIPIECQ------------EKLVPPSVELDV 11017
Query: 266 PLADCTTVTGYNTQLF-CCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
L + V T F +R P P W + +I+ + Y T L I+
Sbjct: 11018 KLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCL 11077
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y N G +V + V
Sbjct: 11078 RRDTGEYQITVSNAAGSKTVAVHLTV 11103
Score = 50.8 bits (120), Expect = 2e-06
Identities = 30/92 (32%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSC 204
P PP S+++ V S TL W+ P+ G + + GY +++ + S W V + +
Sbjct: 19486 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 19545
Query: 205 IVSDLIIGNSYAFRVFAENQCGL---SETAPI 233
+ L G Y +RV+AEN GL SET+P+
Sbjct: 19546 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL 19577
Score = 50.4 bits (119), Expect = 2e-06
Identities = 29/85 (34%), Positives = 45/85 (52%), Gaps = 1/85 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PGPP + + +V S T+ W P G +A++GY ++ D S LW + RT+
Sbjct: 20173 PGPPSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHF 20232
Query: 206 -VSDLIIGNSYAFRVFAENQCGLSE 229
V+ + G Y FRV+AEN G+ +
Sbjct: 20233 KVTTISAGLIYEFRVYAENAAGVGK 20257
Score = 49.7 bits (117), Expect = 4e-06
Identities = 54/223 (24%), Positives = 89/223 (39%), Gaps = 27/223 (12%)
Query: 137 TIDILVIERP----GPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
T + LVI P P+ +++ +V + TL W PP+ G + ++ Y ++ + +
Sbjct: 10207 TSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKF 10266
Query: 193 FTVL-EHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE----TAPITTDLAHIQKAATVY 247
V ++ V L G++Y +RV A N G + T PIT K
Sbjct: 10267 HKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITC------KDELAP 10320
Query: 248 KTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKY 307
T RD K T + + +TG + P+PK+ W K++ D+ + +
Sbjct: 10321 PTLHLDFRD-----KLTIRVGEAFALTGRYS-------GKPKPKVSWFKDEADVLEDDRT 10368
Query: 308 RALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
T +LE K D G Y N G C+V+V
Sbjct: 10369 HIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNV 10411
Score = 49.7 bits (117), Expect = 4e-06
Identities = 29/90 (32%), Positives = 43/90 (47%), Gaps = 11/90 (12%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV------L 196
I PGPP+++++ DV TL W PP+D G + + GY V++ + ++ W V +
Sbjct: 23432 IRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTM 23491
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
Y T L G Y RV A N G
Sbjct: 23492 TRYRSTG-----LTEGLEYEHRVTAINARG 23516
Score = 49.3 bits (116), Expect = 5e-06
Identities = 51/209 (24%), Positives = 80/209 (38%), Gaps = 17/209 (8%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY-TVQKADTKSGLWFTVLEHYHR 201
+ P PP+ +++ ++ SATL W PP G + GY T + + + +T
Sbjct: 12299 LSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKD 12358
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP 261
S +V+ L G Y FRV A N G+S ++A VY+ K + P
Sbjct: 12359 LSLVVTGLKEGKKYKFRVAARNAVGVSLP----------REAEGVYEAK-----EQLLPP 12403
Query: 262 KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIR 321
K P T G ++ V P P W K + ++ + L I+
Sbjct: 12404 KILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIK 12462
Query: 322 KPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
D G Y+ A N G + +V V
Sbjct: 12463 DVTRKDSGYYSLTAENSSGTDTQKIKVVV 12491
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 3/86 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP + ++ + S + W P D G T + GY ++K D K G+ +T T
Sbjct: 18405 PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRD-KEGVRWTKCNKKTLTDLR 18463
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSE 229
V+ L G+SY FRV AEN G+ E
Sbjct: 18464 LRVTGLTEGHSYEFRVAAENAAGVGE 18489
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
A I V + PG P+ + G S TL W P+ G + + Y +++ + KS W V
Sbjct: 21648 AQIQYTVPDAPGIPEPSNIT---GNSITLTWARPESDGGSEIQQYILERREKKSTRWVKV 21704
Query: 196 LEH--YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
+ T V+ L GN Y F V AEN G+ + I+
Sbjct: 21705 ISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGIS 21745
Score = 49.3 bits (116), Expect = 5e-06
Identities = 58/232 (25%), Positives = 90/232 (38%), Gaps = 57/232 (24%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK---ADTKSGLW----FTV 195
++ PG P+ + DV + +L W+ P G + ++GY +++ ++ G W +T+
Sbjct: 22442 VDAPGRPE---VTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTI 22498
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL-----SETAPITTDLAHIQKAATVYKTK 250
+ T +S+ G++Y FRV A+N G+ T P+T
Sbjct: 22499 VSDNFFTVTALSE---GDTYEFRVLAKNAAGVISKGSESTGPVTC--------------- 22540
Query: 251 GFAQRDFSEAPKF---TQPLADCTTV-TGYNTQLFCCVRASPRPKIIWLK--------NK 298
RD PK + D T+ G + L V P PKIIW K K
Sbjct: 22541 ----RDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK 22596
Query: 299 MDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ +Q K RA + C D G YT N G +V V V
Sbjct: 22597 VSLQYTGK-RATAVIKFCDRS-------DSGKYTLTVKNASGTKAVSVMVKV 22640
Score = 49.3 bits (116), Expect = 5e-06
Identities = 55/214 (25%), Positives = 84/214 (39%), Gaps = 25/214 (11%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV--QKAD----TKSGLWFTVL 196
I PG PQ+ ++ D S +L W+ P+D G + + GY + QK D TK T +
Sbjct: 23533 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 23592
Query: 197 EHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRD 256
Y ++ L G Y FRV A N G E A + TV T+ D
Sbjct: 23593 REY-----TLTHLPQGAEYRFRVLACNAGGPGEPAEV---------PGTVKVTEMLEYPD 23638
Query: 257 FSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC 316
+ ++ + + G +L ++ P P W K DI + + T
Sbjct: 23639 YELDERYQEGI---FVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHT 23693
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I++ D G Y N G+ +V +V V
Sbjct: 23694 ELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23727
Score = 48.9 bits (115), Expect = 7e-06
Identities = 52/211 (24%), Positives = 76/211 (36%), Gaps = 22/211 (10%)
Query: 145 RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ--KADTKSGLWFTVLEHYHRT 202
+PGPP + +VD S TL W P G + +LGY V+ KAD + T T
Sbjct: 17422 KPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVT 17481
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+S L Y RV A N+ GL E + + D EAP+
Sbjct: 17482 RFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTV---------------KPEDKLEAPE 17526
Query: 263 F---TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
++ G + ++ + P P+I W + + + K + + L
Sbjct: 17527 LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEF--TDKVQIEKGVNYTQLS 17584
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I D G Y K N G S V V
Sbjct: 17585 IDNCDRNDAGKYILKLENSSGSKSAFVTVKV 17615
Score = 48.1 bits (113), Expect = 1e-05
Identities = 57/221 (25%), Positives = 87/221 (39%), Gaps = 22/221 (9%)
Query: 140 ILVIERPGPPQS---IKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
IL ++ GPP S + + + TL+W P+ G + + GY ++K + V
Sbjct: 8789 ILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVN 8848
Query: 197 EHY-HRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR 255
+ TS +V +L Y FRV A N+ G SE + + + K + +
Sbjct: 8849 KRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRG 8908
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
D + K +P+ VTG P PKI W KN+ I+ +T +
Sbjct: 8909 DTIKV-KAGEPVHIPADVTGL-----------PMPKIEWSKNETVIEKPTDALQITKEEV 8956
Query: 316 ------CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
L I K D G YT A N LG + V+V
Sbjct: 8957 SRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEV 8997
Score = 48.1 bits (113), Expect = 1e-05
Identities = 32/117 (27%), Positives = 54/117 (46%), Gaps = 8/117 (6%)
Query: 123 YQLRV-------QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNT 175
YQ R+ Q LE+ + + PGPP + + S ++W P + G +
Sbjct: 16896 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 16955
Query: 176 ALLGYTVQKADTKSGLWFTVLEH-YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA 231
++GY +++ + S LW V + H T +L G Y FRV+AEN G+ + +
Sbjct: 16956 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKAS 17012
Score = 47.8 bits (112), Expect = 2e-05
Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 1/82 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTSC 204
PGPP ++ D+ + TL W P D G + + GY V++ D + W + T+
Sbjct: 7386 PGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTY 7445
Query: 205 IVSDLIIGNSYAFRVFAENQCG 226
V L Y FRV AEN G
Sbjct: 7446 RVKGLTNKKKYRFRVLAENLAG 7467
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/119 (31%), Positives = 53/119 (44%), Gaps = 18/119 (15%)
Query: 123 YQLRVQLG---GLEATATIDILVIER----PGPPQSIKLVDVWGFSATLEWTPPQDTGNT 175
YQ RV+ G+ I+V + PGPP + +V +L W P G +
Sbjct: 21230 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 21289
Query: 176 ALLGYTVQKADTKSGLWFTVLEHYHRTSCI------VSDLIIGNSYAFRVFAENQCGLS 228
+ G+ V+K + S LW V TS I + L+ G Y FRV+AEN GLS
Sbjct: 21290 EVTGFHVEKKERNSILWQKV-----NTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21343
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/89 (31%), Positives = 37/89 (41%)
Query: 255 RDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG 314
++ S+AP F G N C + P P+I W KN + I +
Sbjct: 26631 KELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRN 26690
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEAS 343
+ SLEIR D G YT KA N G+ S
Sbjct: 26691 VYSLEIRNASVSDSGKYTIKAKNFRGQCS 26719
Score = 47.4 bits (111), Expect = 2e-05
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 3/89 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH--YHRTS 203
P P + +V SA + W P D G + Y ++K +T S W V + + T
Sbjct: 10515 PDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILEKRETMSKRWARVTKDPIHPYTK 10573
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAP 232
V DL+ G Y FRV AEN+ G+ + +P
Sbjct: 10574 FRVPDLLEGCQYEFRVSAENEIGIGDPSP 10602
Score = 47.0 bits (110), Expect = 3e-05
Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 1/87 (1%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRT 202
++PG P ++ V T+ W PP+ G ++ GY ++K + S W V +
Sbjct: 11897 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPER 11956
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSE 229
V +L+ + Y FRV AEN+ G+ E
Sbjct: 11957 RMKVQNLLPDHEYQFRVKAENEIGIGE 11983
Score = 47.0 bits (110), Expect = 3e-05
Identities = 50/215 (23%), Positives = 76/215 (35%), Gaps = 30/215 (13%)
Query: 145 RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW--FTVLEHYHRT 202
+PGPP + +++D S ++ W P G + + GY V+ A + W T T
Sbjct: 15258 KPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKAT 15317
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
S ++ L Y R++A N GL E A V T R +
Sbjct: 15318 SYTITGLTENQEYKIRIYAMNSEGLGE-------------PALVPGTPKAEDRMLPPEIE 15364
Query: 263 FTQPLADCTTVTGYNT-QLFCCVRASPRPKIIWLK------NKMDIQGNPKYRALTHLGI 315
L T+ T +LF ++ P P++ W + +K I+ Y L
Sbjct: 15365 LDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI---- 15420
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ FD G Y N G S V V
Sbjct: 15421 ----VGNVNRFDSGKYILTVENSSGSKSAFVNVRV 15451
Score = 46.6 bits (109), Expect = 3e-05
Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
PGPP ++ +VDV L+W PP++ G + Y ++K + W + +
Sbjct: 7687 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7746
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
V+D+I G F+V AEN+ G+ + T L+
Sbjct: 7747 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILS 7780
Score = 46.2 bits (108), Expect = 4e-05
Identities = 45/206 (21%), Positives = 73/206 (35%), Gaps = 15/206 (7%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF---TVLEHYHRTSC 204
PP +++DV + +L W P+ G + ++GY V+ W T +
Sbjct: 12695 PPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEY 12754
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFT 264
+ L Y FR A +S + + + T+ + D S A K
Sbjct: 12755 TATGLEEKAQYQFRAIARTAVNISPPSEPSDPV-------TILAENVPPRIDLSVAMKSL 12807
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
T G N L V P P + W K+ ++ + +C+LE+
Sbjct: 12808 -----LTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVN 12862
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDV 350
D G YT A N G S ++ V
Sbjct: 12863 RKDSGDYTITAENSSGSKSATIKLKV 12888
Score = 46.2 bits (108), Expect = 4e-05
Identities = 28/88 (31%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
P P++ ++ V S + W P G + +LGY ++K D + W +
Sbjct: 16240 PDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRL 16299
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAP 232
V+ LI + Y FRV AEN GLSE +P
Sbjct: 16300 RVTGLIENHDYEFRVSAENAAGLSEPSP 16327
Score = 45.8 bits (107), Expect = 6e-05
Identities = 27/95 (28%), Positives = 43/95 (45%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSL 318
E P+ Q L T +G + + P+PKI W K + + K + L +L
Sbjct: 3191 EPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTL 3250
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ + P D +YTC+A N G A+ + V+VP
Sbjct: 3251 LLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVP 3285
Score = 45.8 bits (107), Expect = 6e-05
Identities = 35/121 (28%), Positives = 52/121 (42%), Gaps = 13/121 (10%)
Query: 120 SGRYQLRVQLG---GLEATATIDILVIERP----GPPQSIKLVDVWGFSATLEWTPPQDT 172
+G+Y+ RV+ G+ D +VI+ P GPP K++ S + WTPP D
Sbjct: 9069 NGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDN 9128
Query: 173 GNTALLGYTVQKADTKSGLWFTVLE------HYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
G + + GY ++K + S W V V L+ G Y FR A N G
Sbjct: 9129 GGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAG 9188
Query: 227 L 227
+
Sbjct: 9189 I 9189
Score = 45.8 bits (107), Expect = 6e-05
Identities = 48/207 (23%), Positives = 76/207 (36%), Gaps = 18/207 (8%)
Query: 144 ERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS 203
+ PGP +K+ V S ++ W P G + ++GY V T+ W V++
Sbjct: 13385 QTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL-TEENKWQRVMKSL-SLQ 13442
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
DL G Y FRV AEN+ G + IT +A A KG
Sbjct: 13443 YSAKDLTEGKEYTFRVSAENENGEGTPSEITV-VARDDVVAPDLDLKGL----------- 13490
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
P N +L ++ P P + W K + + + + + +L +
Sbjct: 13491 --PDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDC 13548
Query: 324 GPFDGGIYTCKAVNPLG--EASVDCRV 348
D G YT N G E ++ +V
Sbjct: 13549 QKSDAGKYTITLKNVAGTKEGTISIKV 13575
Score = 45.4 bits (106), Expect = 8e-05
Identities = 29/86 (33%), Positives = 39/86 (45%), Gaps = 2/86 (2%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY--HRTS 203
P PP + V ++WT P+ G + Y V K + KS W V + Y + T
Sbjct: 22743 PSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTR 22802
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSE 229
V+ L+ G Y FRV A N G SE
Sbjct: 22803 LKVTSLMEGCDYQFRVTAVNAAGNSE 22828
Score = 45.1 bits (105), Expect = 1e-04
Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 5/171 (2%)
Query: 61 QTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRR---VSVRNGEQDSILFIREAQR 117
Q+ + G T G P P+ W DG + T V + + + L I +
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERPGPPQSI-KLVDVWGFSATLEWTPPQDTG-NT 175
A+SGRY L+ G +AT+T ++LV PP + +L + + + TG T
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT 132
Query: 176 ALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCG 226
++ + A+ +S L F + + S ++++ +S + V A N G
Sbjct: 133 PVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVG 183
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/94 (28%), Positives = 41/94 (43%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AP + + G+ + C ++++P + W K +I + K + I SLE
Sbjct: 4336 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4395
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
I + D G YTCKA N G S + V VP
Sbjct: 4396 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 9/106 (8%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
LE+ + + P PP++ ++ + S + W P G + ++ Y V++ D
Sbjct: 15144 LESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQR 15203
Query: 192 WF-----TVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAP 232
W T+ + ++ VS L G+ Y FR+ AEN G+S +P
Sbjct: 15204 WIKCNKKTLTDLRYK----VSGLTEGHEYEFRIMAENAAGISAPSP 15245
Score = 44.7 bits (104), Expect = 1e-04
Identities = 40/152 (26%), Positives = 62/152 (40%), Gaps = 18/152 (11%)
Query: 203 SCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
S I+ +S + V A+N+ G S + I T A ++ K P
Sbjct: 1468 SLIIVPATPSDSGEWTVVAQNRAGRSSISVILT------VEAVEHQVK----------PM 1511
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN--PKYRALTHLGICSLEI 320
F + L + G ++ +P P I+WLKN I + PK R G +L+I
Sbjct: 1512 FVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKI 1571
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
D YT A+N G + C+V+V+V
Sbjct: 1572 DSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 2/88 (2%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHY-HRTSC 204
P P + DV S ++W P+D G+ +LGY ++K + S W V + +
Sbjct: 8406 PDAPDKPIVEDVTSNSMLVKWNEPKDNGSP-ILGYWLEKREVNSTHWSRVNKSLLNALKA 8464
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSETAP 232
V L+ G +Y FRV AEN G + +P
Sbjct: 8465 NVDGLLEGLTYVFRVCAENAAGPGKFSP 8492
Score = 44.3 bits (103), Expect = 2e-04
Identities = 28/98 (28%), Positives = 47/98 (47%), Gaps = 1/98 (1%)
Query: 133 EATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
E++A + PGPP + K+V + + W P + G + ++GY ++ + S LW
Sbjct: 19077 ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILW 19136
Query: 193 FTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
+ T VS L G Y +RV+AEN G+ +
Sbjct: 19137 SKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGK 19174
Score = 44.3 bits (103), Expect = 2e-04
Identities = 47/208 (22%), Positives = 81/208 (38%), Gaps = 22/208 (10%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206
PP ++ ++ S +L+W+ P G + GY V++ + G W + T V
Sbjct: 19190 PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEV 19249
Query: 207 SDLIIGNSYAFRVFAENQC-GLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
++L Y FRVFA N +SE + T + +D E P+
Sbjct: 19250 TELTEDQRYEFRVFARNAADSVSEPSESTGPI---------------IVKDDVEPPRVMM 19294
Query: 266 PL--ADCTTV-TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
+ D V G ++ + P P I W K+ ++I+ + ++ L ++
Sbjct: 19295 DVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKD 19354
Query: 323 PGPFDGGIYTCKAVNPLGEAS--VDCRV 348
D G Y N G S V+C+V
Sbjct: 19355 CIRRDTGQYVLTLKNVAGTRSVAVNCKV 19382
Score = 43.9 bits (102), Expect = 2e-04
Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PG P + V S T+ W P+ G + + GY ++ DT S W V + +
Sbjct: 9820 PGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTL 9879
Query: 206 -----VSDLIIGNSYAFRVFAENQCGL 227
V+ LI G+ Y FRV+A N G+
Sbjct: 9880 GVSYKVTGLIEGSDYQFRVYAINAAGV 9906
Score = 43.5 bits (101), Expect = 3e-04
Identities = 55/216 (25%), Positives = 80/216 (37%), Gaps = 30/216 (13%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRT 202
I PGPP ++ D + LEW PP G ++GY V K + W E +
Sbjct: 8503 ISPPGPPIP-RVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKV 8561
Query: 203 -SCIVSDLIIGNSYAFRVFAENQCG---LSETAPITTDLAHIQKAATV---YKTKGFAQR 255
V ++ G Y RV A N G ET P+T +A Q+ V KG Q
Sbjct: 8562 RQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVT--VAEPQEPPAVELDVSVKGGIQ- 8618
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
+ G ++ V P P +W K + ++ + + ++G
Sbjct: 8619 ----------------IMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRV--VIDNVGT 8660
Query: 316 CS-LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
S L I+ D G Y A N G RV+V
Sbjct: 8661 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEV 8696
Score = 43.5 bits (101), Expect = 3e-04
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 2/105 (1%)
Query: 248 KTKGFAQRDFS--EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNP 305
K + +Q+ F+ AP+ T + G NT+ V++ P ++ W N +++Q +
Sbjct: 25862 KYEVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESS 25921
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
K G+ +LEI D G Y N GEAS +DV
Sbjct: 25922 KIHYTNTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L++ A I + PGPP + + + ++W P + G T ++GY +++ + S L
Sbjct: 17994 LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 18053
Query: 192 WFTVLE-HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
W + + T + L G Y F+V AEN G+ + + ++
Sbjct: 18054 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVS 18097
Score = 42.7 bits (99), Expect = 5e-04
Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
Query: 131 GLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
GL++ + + P P +VDV S +L WT P+ TG + + GY ++ + S
Sbjct: 13664 GLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSL 13723
Query: 191 LWFTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSE 229
LW + R V+ L G Y FRV A N G+ +
Sbjct: 13724 LWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGK 13763
Score = 42.0 bits (97), Expect = 8e-04
Identities = 29/106 (27%), Positives = 42/106 (39%), Gaps = 3/106 (2%)
Query: 248 KTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQ---GN 304
K + R P+FT PL + T G N + + P P + W K+ I+ +
Sbjct: 25180 KRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDND 25239
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
KY + G+ L I D YT A N GE S ++ V
Sbjct: 25240 KKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285
Score = 41.6 bits (96), Expect = 0.001
Identities = 22/84 (26%), Positives = 41/84 (48%), Gaps = 1/84 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHR-TSC 204
P P++ ++ V + W P G + ++GY +++ + S LW + R T
Sbjct: 12595 PSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEY 12654
Query: 205 IVSDLIIGNSYAFRVFAENQCGLS 228
+ L+ G Y+FR++A N+ G S
Sbjct: 12655 PCAGLVEGLEYSFRIYALNKAGSS 12678
Score = 41.6 bits (96), Expect = 0.001
Identities = 49/211 (23%), Positives = 75/211 (35%), Gaps = 26/211 (12%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL--EHYHRTS 203
PGPP + K+ D S +L W+ P G + GY V+ + + W T
Sbjct: 18506 PGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQ 18565
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKF 263
V+ L Y FR+ A N G+ E A + + ++ E P+
Sbjct: 18566 FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERI---------------EPPEI 18610
Query: 264 TQPLADCTTV----TGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AD V +LF ++ P P++ W K + + + + L
Sbjct: 18611 ELD-ADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTS--SFTMLV 18667
Query: 320 IRKPGPFDGGIYTCKAVNPLGE--ASVDCRV 348
I FD G Y N G A V+ RV
Sbjct: 18668 IDNVTRFDSGRYNLTLENNSGSKTAFVNVRV 18698
Score = 41.2 bits (95), Expect = 0.001
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 13/100 (13%)
Query: 141 LVIERPG-PPQSIKLVDVWGFSA---TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVL 196
++ E P PP + +V+ SA ++ W P G + ++GY V+K + + LW
Sbjct: 22335 IIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWV--- 22391
Query: 197 EHYHRTSCI-----VSDLIIGNSYAFRVFAENQCGLSETA 231
++ C+ V+ L+ G Y FR +A N G+S+ +
Sbjct: 22392 -KENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22430
Score = 40.4 bits (93), Expect = 0.002
Identities = 36/120 (30%), Positives = 50/120 (41%), Gaps = 8/120 (6%)
Query: 236 DLAHIQKAATVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIW 294
D +Q A +KT A E P +FT+PL D T G L C V + K+ W
Sbjct: 5764 DAGEVQLTAKDFKTH--ANLFVKEPPVEFTKPLEDQTVEEGATAVLECEV-SRENAKVKW 5820
Query: 295 LKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
KN +I + KY + + L I P D YTC A + C ++V P+
Sbjct: 5821 FKNGTEILKSKKYEIVADGRVRKLVIHDCTPEDIKTYTCDA----KDFKTSCNLNVVPPH 5876
Score = 39.7 bits (91), Expect = 0.004
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 1/104 (0%)
Query: 132 LEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGL 191
L + T+ + PGPP + + S ++W P G + ++GY +++ + S L
Sbjct: 15830 LNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSIL 15889
Query: 192 WFTVLEH-YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
W + + +T + L G Y FRV AEN G+ + + ++
Sbjct: 15890 WVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 15933
Score = 39.7 bits (91), Expect = 0.004
Identities = 55/295 (18%), Positives = 110/295 (37%), Gaps = 32/295 (10%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALD-TRRVSVRNGEQDSILFIREAQRADSGRYQLR 126
G V G+P P+ W + + + VS+ L IR A +DSG+Y ++
Sbjct: 26651 GQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKYTIK 26710
Query: 127 VQ--LGGLEATATIDIL-VIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLG---- 179
+ G ATA++ +L ++E P ++ +G+T+L G
Sbjct: 26711 AKNFRGQCSATASLMVLPLVEEPSREVVLR-----------------TSGDTSLQGSFSS 26753
Query: 180 YTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPI-TTDLA 238
+VQ + +K F+ +S ++ + E+ +S ++ + +++
Sbjct: 26754 QSVQMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMT 26813
Query: 239 HIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWL--K 296
++ + + G PK +D + G + C P P++ W
Sbjct: 26814 QLESSTSKMLKAGIR----GIPPKIEALPSDISIDEGKVLTVACAFTGEPTPEVTWSCGG 26869
Query: 297 NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
K+ Q ++ + +L I DGG+YT N G S + ++
Sbjct: 26870 RKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHIR 26924
Score = 39.3 bits (90), Expect = 0.005
Identities = 59/346 (17%), Positives = 123/346 (35%), Gaps = 52/346 (15%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLI 75
K+ E +D + +++ + P+ PI P I L+ T + +
Sbjct: 26323 KISETKKSDQKTTESTVTRKTEPKAPE---PISSKPVI--VTGLQDTTVSS-DSVAKFAV 26376
Query: 76 PFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQ--LGGL 132
G+P+P AIWT DG A+ + + + L I + +DSG Y V+ G +
Sbjct: 26377 KATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSV 26436
Query: 133 EATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
++ + I I + Q + + + ++ AL ++ ++ KS
Sbjct: 26437 SSSCKLTIKAI-KDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKS--- 26492
Query: 193 FTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGF 252
+ + L E A ++K+A K
Sbjct: 26493 -----------------------------QEKLALKEEASKVLISEEVKKSAATSLEKSI 26523
Query: 253 AQRDFSEAPKFTQPLADCTTVTGYNTQ--------LFCCVRASPRPKIIWLKNKMDIQGN 304
+ ++ + ++ + + ++TQ L + + W+ N +++ +
Sbjct: 26524 VHEEITKTSQASEEVRTHAEIKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNS 26583
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+YR +L I++ D GI TC ++ E V C+ D+
Sbjct: 26584 EEYRYGVSGSDQTLTIKQASHRDEGILTC--ISKTKEGIVKCQYDL 26627
Score = 38.9 bits (89), Expect = 0.007
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Query: 163 TLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFA 221
T+ W PP D G + + GY ++K +T++ W V + + + L G Y FRV A
Sbjct: 13008 TVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTA 13067
Query: 222 ENQCG 226
N+ G
Sbjct: 13068 INKAG 13072
Score = 38.5 bits (88), Expect = 0.009
Identities = 41/162 (25%), Positives = 67/162 (41%), Gaps = 25/162 (15%)
Query: 2 EAATAPEVAAGSKLKVKEA-----SPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLP 56
EA E AA K +K SP +AE + PG G P +E P +
Sbjct: 4561 EAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPP-------DEAPFTYQL 4613
Query: 57 RALRQTYIRKVGDTVNLLIPFQGKP-------KPQAI---WTHDGCAL--DTRRVSVRNG 104
+A+ +++++ D + F G P W DG + + + +G
Sbjct: 4614 KAVPLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADG 4673
Query: 105 EQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERP 146
+ D L I + Q +D+G Y ++LG E T+T ++V E P
Sbjct: 4674 K-DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELP 4714
Score = 38.1 bits (87), Expect = 0.012
Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 3/115 (2%)
Query: 29 QASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWT 88
+A+ G G + T +LL E P ++ R T + G V L + G P P +
Sbjct: 81 KATNGSGQATSTAELLVKAETAPPNFVQRLQSMTV--RQGSQVRLQVRVTGIPTPVVKFY 138
Query: 89 HDGCALDTRRVSVRNGEQDSI-LFIREAQRADSGRYQLRVQLGGLEATATIDILV 142
DG + + + E D L I EA DSG Y + AT+T ++LV
Sbjct: 139 RDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLV 193
Score = 37.0 bits (84), Expect = 0.027
Identities = 23/83 (27%), Positives = 37/83 (44%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P F Q L T G +L V P P + + ++ +IQ + ++ + SL I
Sbjct: 104 PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163
Query: 321 RKPGPFDGGIYTCKAVNPLGEAS 343
+ P D G Y+ A N +G A+
Sbjct: 164 AEAYPEDSGTYSVNATNSVGRAT 186
Score = 36.6 bits (83), Expect = 0.035
Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 22/126 (17%)
Query: 13 SKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKV----- 67
+++ SPA P + SPG+ +EE + L R + ++ K
Sbjct: 1374 ARMSPARMSPARMSPARMSPGRR-----------LEETDESQLERLYKPVFVLKPVSFKC 1422
Query: 68 --GDTVNLLIPFQGKPKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIREAQRADSGR 122
G T + G+P P+ W HDG + T +V ++ S++ + A +DSG
Sbjct: 1423 LEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGE 1481
Query: 123 YQLRVQ 128
+ + Q
Sbjct: 1482 WTVVAQ 1487
Score = 36.6 bits (83), Expect = 0.035
Identities = 25/93 (26%), Positives = 37/93 (39%), Gaps = 1/93 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P PL D T G + C V + K+ W I+ + +R LEI
Sbjct: 3299 PAIITPLQDTVTSEGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEI 3357
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ P D G YT A N +G+ S + ++ P
Sbjct: 3358 AEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3390
Score = 35.4 bits (80), Expect = 0.078
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 2/96 (2%)
Query: 258 SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN--PKYRALTHLGI 315
++AP FTQPL + G + P P++ W ++ I + P + G
Sbjct: 3 TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62
Query: 316 CSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L I + G Y+ KA N G+A+ + VK
Sbjct: 63 AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 1/81 (1%)
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA-LTHLGICSLEIR 321
F + + + G C + P PKI W K+ I+ +Y+ G SL I
Sbjct: 1247 FDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIP 1306
Query: 322 KPGPFDGGIYTCKAVNPLGEA 342
P D GIYT A N G A
Sbjct: 1307 VVLPEDEGIYTAFASNIKGNA 1327
Score = 34.7 bits (78), Expect = 0.13
Identities = 18/64 (28%), Positives = 27/64 (42%)
Query: 288 PRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCR 347
P + WL + ++ + R + G CSL+ D GI TC+A N G
Sbjct: 1686 PTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSAT 1745
Query: 348 VDVK 351
+ VK
Sbjct: 1746 LIVK 1749
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/86 (29%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPK-YRALTHLGICS 317
EAPK + + T G + V P P+ W KN + I+ + + Y +C
Sbjct: 2030 EAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCE 2089
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEAS 343
L IR D KA+N GE S
Sbjct: 2090 LVIRDVTAEDSASIMVKAINIAGETS 2115
Score = 33.9 bits (76), Expect = 0.23
Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL-GICSLE 319
P F + L G V P P + W K + + Y + + G +
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634
Query: 320 IRKPGPFDGGIYTCKAVNPLGEAS 343
+ P D G+Y CKA N LGE++
Sbjct: 3635 VNDPQREDSGLYICKAENMLGEST 3658
Score = 33.9 bits (76), Expect = 0.23
Identities = 64/278 (23%), Positives = 101/278 (36%), Gaps = 41/278 (14%)
Query: 69 DTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRV 127
DT+ L+ KP + IW D ++T R + + IL I+ A D+G Y R+
Sbjct: 5981 DTIKLVCEVS-KPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRL 6039
Query: 128 QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ-KAD 186
+ + L E PQ++++ LE + + + + VQ K D
Sbjct: 6040 PSSRTDGKVKVHELAAEFISKPQNLEI---------LEGEKAEFVCSISKESFPVQWKRD 6090
Query: 187 TK---SGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
K SG + V+ + +V D + + + V G + A AH+
Sbjct: 6091 DKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMV----GAARAA------AHL--- 6137
Query: 244 ATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
TV E + PL D T V +F C + K W +N+ I
Sbjct: 6138 -TVI-----------EKLRIVVPLKD-TRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFD 6184
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
+ KY L + +L IR D Y N GE
Sbjct: 6185 SSKYIILQKDLVYTLRIRDAHLDDQANYNVSLTNHRGE 6222
Score = 33.5 bits (75), Expect = 0.30
Identities = 17/61 (27%), Positives = 26/61 (42%)
Query: 291 KIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
++ W ++ + KY G+ L ++ D G Y CK VN GE S + V
Sbjct: 25102 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25161
Query: 351 K 351
K
Sbjct: 25162 K 25162
Score = 33.1 bits (74), Expect = 0.39
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 260 APKF-TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL--THLGIC 316
AP F T+P+ V G + C V +P+P + W K+ + + +Y+ G C
Sbjct: 1035 APYFITKPVVQ-KLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGEC 1093
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEAS 343
L I D G YT N GE S
Sbjct: 1094 KLVISMTFADDAGEYTIVVRNKHGETS 1120
Score = 32.7 bits (73), Expect = 0.51
Identities = 21/74 (28%), Positives = 29/74 (39%)
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
FTQ L D F C + P K+ W K+ M++ KYR + + L I
Sbjct: 2130 FTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILT 2189
Query: 323 PGPFDGGIYTCKAV 336
D Y+C V
Sbjct: 2190 IDTSDAEDYSCVLV 2203
Score = 32.0 bits (71), Expect = 0.86
Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
Query: 246 VYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNP 305
VY TK ++++ P F + +++ G L V P+PKI W N + + +
Sbjct: 3443 VYPTKFDSEKE-GTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSA 3501
Query: 306 KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
Y+ + SL I D G YTC A N G+
Sbjct: 3502 DYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGK 3537
Score = 31.2 bits (69), Expect = 1.5
Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 245 TVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
T + K A+ EAP +F + L D TVT ++ +F C + + + W +N +I+
Sbjct: 6309 TAGQDKSVAELLIIEAPTEFVEHLED-QTVTEFDDAVFSCQLSREKANVKWYRNGREIKE 6367
Query: 304 NPKYR 308
KY+
Sbjct: 6368 GKKYK 6372
Score = 30.8 bits (68), Expect = 1.9
Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 12/114 (10%)
Query: 79 GKPKPQAIWTHDGCALDTR--RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATA 136
G+P P W + L T + N + + QR DSG Y + + E+T
Sbjct: 3600 GEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTC 3659
Query: 137 TIDILVIERPGPPQSIKLVDVWGFSATLEWTP--PQDTGNTALLGYTVQKADTK 188
++LV+ ++ D+ + TP P+D T L G V+ D++
Sbjct: 3660 AAELLVL--------LEDTDMTDTPCKAKSTPEAPEDFPQTPLKGPAVEALDSE 3705
Score = 30.0 bits (66), Expect = 3.3
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 275 GYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCK 334
G + C V P+PK+ W N I+ + ++R + + GI L+I +D G
Sbjct: 1809 GETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFR-VRYDGIHYLDIVDCKSYDTGEVKVT 1867
Query: 335 AVNPLGEASVDCRVDVK 351
A NP G +++++
Sbjct: 1868 AENPEGVIEHKVKLEIQ 1884
Score = 28.9 bits (63), Expect = 7.3
Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPK-IIWLKNKMDIQGNPKYRALTHLGICS 317
EA K + L + T VT +F P K + W+KN + ++ N KY I S
Sbjct: 2659 EAVKIKKTLKNLT-VTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYS 2717
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
L I+ D +Y + LG R+ V+
Sbjct: 2718 LRIKNCAIVDESVYGFR----LGRLGASARLHVE 2747
>gi|116008194 myosin light chain kinase isoform 3A [Homo sapiens]
Length = 1863
Score = 63.5 bits (153), Expect = 3e-10
Identities = 36/91 (39%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AP F+ L DC + G + L C VR +P P+I WL N IQ R+ G+ L
Sbjct: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELH 569
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I+ P D G YTC A N LG+ S V V
Sbjct: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Score = 60.8 bits (146), Expect = 2e-09
Identities = 85/357 (23%), Positives = 134/357 (37%), Gaps = 33/357 (9%)
Query: 18 KEASPADAEPPQASPGQGAG---SPTPQLLPPIEEHPKIWLPR--ALRQTYIRKVGDTVN 72
+ A P A P PG G+ S P+E P+ + Q+ K TV
Sbjct: 373 RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVK 432
Query: 73 LLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQ--DSILFIREAQRADSGRYQLRVQ-- 128
G PKP+ W +G + + S+ E L + +A+ DSG Y
Sbjct: 433 FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
Query: 129 LGGLEATATIDI--LVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKAD 186
G L + T+ + L + P S L D A +E G +L +V+
Sbjct: 493 QGQLSCSWTLQVERLAVMEVAPSFSSVLKDC----AVIE-------GQDFVLQCSVRGTP 541
Query: 187 TKSGLWFTVLE--HYHRTSCI-------VSDLIIGNSYAFRVFAENQCGLSETAPITTDL 237
W + Y R++C + D + + + AEN G + T
Sbjct: 542 VPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT-- 599
Query: 238 AHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN 297
H +K++ + AP F Q L+D + G + V +P P++IWL N
Sbjct: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
Query: 298 KMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
+IQ + + SL I++ P D G YTC+A N GE + V+ P+
Sbjct: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
Score = 57.8 bits (138), Expect = 1e-08
Identities = 57/219 (26%), Positives = 90/219 (41%), Gaps = 9/219 (4%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQ---TYIRKVGDTVN 72
++K P + PP A T + P + PK +P + Q + G++V
Sbjct: 1200 EMKSRRPKSSLPPVLGTESDA---TVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1256
Query: 73 LLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGG 131
L G W + ++ + V N E S L I A++ G Y L V+
Sbjct: 1257 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1316
Query: 132 LEATATIDILVIERPGPPQSIKLV-DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
A +++ V+++P PP D+ S TL W G +A+ Y+++ D+ +
Sbjct: 1317 GSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
W L TS V DL+ + Y FRV A N G SE
Sbjct: 1377 TW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
Score = 54.7 bits (130), Expect = 1e-07
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG-ICSL 318
AP F Q L D G L C V + P IIW N ++ K+ L+ G +CS+
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK-TTKFIILSQEGSLCSV 1155
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I K P D G+Y C A N G+A C+V V
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 52.8 bits (125), Expect = 5e-07
Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 1/125 (0%)
Query: 228 SETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRAS 287
S T+P+ + ++ + + A+ P F++ + D V G + C +
Sbjct: 1725 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1784
Query: 288 PRPKIIWLKNKMDIQGNPKYRA-LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDC 346
P P+++W K+ I+ + ++ G CSL I D YTCKAVN LGEA+
Sbjct: 1785 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1844
Query: 347 RVDVK 351
+ V+
Sbjct: 1845 ELIVE 1849
Score = 51.6 bits (122), Expect = 1e-06
Identities = 26/91 (28%), Positives = 42/91 (46%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
PKF L G + C + P+P++ WLK + +Q + + G+ LEI
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
D G+YTC VN G+AS+ + ++
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/115 (26%), Positives = 44/115 (38%), Gaps = 1/115 (0%)
Query: 238 AHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN 297
+HI K + +EAP F P + G + VR P P++ W +N
Sbjct: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
Query: 298 KMDIQGNPKYRALTHL-GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
I ++ + G SL I D G YTC+A N G V + V+
Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 35.8 bits (81), Expect = 0.060
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN-KMDIQGNPKYRALTHLGICSLE 319
P F T G + + C + P P + WL++ K + + L + + +L
Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
++K P+ G Y N +GE S C+V + + N
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECS--CQVSLMLQN 813
Score = 32.0 bits (71), Expect = 0.86
Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 4/132 (3%)
Query: 15 LKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQ--TYIRKVGDTVN 72
L ++E P D AG Q + ++E P + + + +G +V
Sbjct: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
Query: 73 LLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG 130
+ G P P W DG AL DT V E L +++ Q +G+Y++ ++
Sbjct: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
Query: 131 GLEATATIDILV 142
E + + +++
Sbjct: 800 VGECSCQVSLML 811
>gi|116008192 myosin light chain kinase isoform 1 [Homo sapiens]
Length = 1914
Score = 63.5 bits (153), Expect = 3e-10
Identities = 36/91 (39%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AP F+ L DC + G + L C VR +P P+I WL N IQ R+ G+ L
Sbjct: 513 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELH 569
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I+ P D G YTC A N LG+ S V V
Sbjct: 570 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 600
Score = 60.8 bits (146), Expect = 2e-09
Identities = 85/357 (23%), Positives = 134/357 (37%), Gaps = 33/357 (9%)
Query: 18 KEASPADAEPPQASPGQGAG---SPTPQLLPPIEEHPKIWLPR--ALRQTYIRKVGDTVN 72
+ A P A P PG G+ S P+E P+ + Q+ K TV
Sbjct: 373 RPAPPRPATFPTRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVK 432
Query: 73 LLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQ--DSILFIREAQRADSGRYQLRVQ-- 128
G PKP+ W +G + + S+ E L + +A+ DSG Y
Sbjct: 433 FRCEVSGIPKPEVAWFLEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNA 492
Query: 129 LGGLEATATIDI--LVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKAD 186
G L + T+ + L + P S L D A +E G +L +V+
Sbjct: 493 QGQLSCSWTLQVERLAVMEVAPSFSSVLKDC----AVIE-------GQDFVLQCSVRGTP 541
Query: 187 TKSGLWFTVLE--HYHRTSCI-------VSDLIIGNSYAFRVFAENQCGLSETAPITTDL 237
W + Y R++C + D + + + AEN G + T
Sbjct: 542 VPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDHGTYTCLAENALGQVSCSAWVT-- 599
Query: 238 AHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN 297
H +K++ + AP F Q L+D + G + V +P P++IWL N
Sbjct: 600 VHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHN 659
Query: 298 KMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
+IQ + + SL I++ P D G YTC+A N GE + V+ P+
Sbjct: 660 GNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 716
Score = 57.8 bits (138), Expect = 1e-08
Identities = 57/219 (26%), Positives = 90/219 (41%), Gaps = 9/219 (4%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQ---TYIRKVGDTVN 72
++K P + PP A T + P + PK +P + Q + G++V
Sbjct: 1200 EMKSRRPKSSLPPVLGTESDA---TVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1256
Query: 73 LLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGG 131
L G W + ++ + V N E S L I A++ G Y L V+
Sbjct: 1257 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1316
Query: 132 LEATATIDILVIERPGPPQSIKLV-DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
A +++ V+++P PP D+ S TL W G +A+ Y+++ D+ +
Sbjct: 1317 GSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1376
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
W L TS V DL+ + Y FRV A N G SE
Sbjct: 1377 TW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1414
Score = 54.7 bits (130), Expect = 1e-07
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG-ICSL 318
AP F Q L D G L C V + P IIW N ++ K+ L+ G +CS+
Sbjct: 1097 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK-TTKFIILSQEGSLCSV 1155
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I K P D G+Y C A N G+A C+V V
Sbjct: 1156 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1187
Score = 52.8 bits (125), Expect = 5e-07
Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 1/125 (0%)
Query: 228 SETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRAS 287
S T+P+ + ++ + + A+ P F++ + D V G + C +
Sbjct: 1776 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1835
Query: 288 PRPKIIWLKNKMDIQGNPKYRA-LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDC 346
P P+++W K+ I+ + ++ G CSL I D YTCKAVN LGEA+
Sbjct: 1836 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1895
Query: 347 RVDVK 351
+ V+
Sbjct: 1896 ELIVE 1900
Score = 51.6 bits (122), Expect = 1e-06
Identities = 26/91 (28%), Positives = 42/91 (46%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
PKF L G + C + P+P++ WLK + +Q + + G+ LEI
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
D G+YTC VN G+AS+ + ++
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/115 (26%), Positives = 44/115 (38%), Gaps = 1/115 (0%)
Query: 238 AHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN 297
+HI K + +EAP F P + G + VR P P++ W +N
Sbjct: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
Query: 298 KMDIQGNPKYRALTHL-GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
I ++ + G SL I D G YTC+A N G V + V+
Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 35.8 bits (81), Expect = 0.060
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN-KMDIQGNPKYRALTHLGICSLE 319
P F T G + + C + P P + WL++ K + + L + + +L
Sbjct: 721 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 780
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
++K P+ G Y N +GE S C+V + + N
Sbjct: 781 LKKVQPWHAGQYEILLKNRVGECS--CQVSLMLQN 813
Score = 32.0 bits (71), Expect = 0.86
Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 4/132 (3%)
Query: 15 LKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQ--TYIRKVGDTVN 72
L ++E P D AG Q + ++E P + + + +G +V
Sbjct: 680 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 739
Query: 73 LLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG 130
+ G P P W DG AL DT V E L +++ Q +G+Y++ ++
Sbjct: 740 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 799
Query: 131 GLEATATIDILV 142
E + + +++
Sbjct: 800 VGECSCQVSLML 811
>gi|116008190 myosin light chain kinase isoform 3B [Homo sapiens]
Length = 1794
Score = 63.5 bits (153), Expect = 3e-10
Identities = 36/91 (39%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AP F+ L DC + G + L C VR +P P+I WL N IQ R+ G+ L
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELH 500
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I+ P D G YTC A N LG+ S V V
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 57.8 bits (138), Expect = 1e-08
Identities = 57/219 (26%), Positives = 90/219 (41%), Gaps = 9/219 (4%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQ---TYIRKVGDTVN 72
++K P + PP A T + P + PK +P + Q + G++V
Sbjct: 1131 EMKSRRPKSSLPPVLGTESDA---TVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1187
Query: 73 LLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGG 131
L G W + ++ + V N E S L I A++ G Y L V+
Sbjct: 1188 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1247
Query: 132 LEATATIDILVIERPGPPQSIKLV-DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
A +++ V+++P PP D+ S TL W G +A+ Y+++ D+ +
Sbjct: 1248 GSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1307
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
W L TS V DL+ + Y FRV A N G SE
Sbjct: 1308 TW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
Score = 54.7 bits (130), Expect = 1e-07
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG-ICSL 318
AP F Q L D G L C V + P IIW N ++ K+ L+ G +CS+
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK-TTKFIILSQEGSLCSV 1086
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I K P D G+Y C A N G+A C+V V
Sbjct: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
Score = 52.8 bits (125), Expect = 5e-07
Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 1/125 (0%)
Query: 228 SETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRAS 287
S T+P+ + ++ + + A+ P F++ + D V G + C +
Sbjct: 1656 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1715
Query: 288 PRPKIIWLKNKMDIQGNPKYRA-LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDC 346
P P+++W K+ I+ + ++ G CSL I D YTCKAVN LGEA+
Sbjct: 1716 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1775
Query: 347 RVDVK 351
+ V+
Sbjct: 1776 ELIVE 1780
Score = 51.6 bits (122), Expect = 1e-06
Identities = 26/91 (28%), Positives = 42/91 (46%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
PKF L G + C + P+P++ WLK + +Q + + G+ LEI
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
D G+YTC VN G+AS+ + ++
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/95 (32%), Positives = 46/95 (48%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AP F Q L+D + G + V +P P++IWL N +IQ + + SL
Sbjct: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 612
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
I++ P D G YTC+A N GE + V+ P+
Sbjct: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 647
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/115 (26%), Positives = 44/115 (38%), Gaps = 1/115 (0%)
Query: 238 AHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN 297
+HI K + +EAP F P + G + VR P P++ W +N
Sbjct: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
Query: 298 KMDIQGNPKYRALTHL-GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
I ++ + G SL I D G YTC+A N G V + V+
Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 35.8 bits (81), Expect = 0.060
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN-KMDIQGNPKYRALTHLGICSLE 319
P F T G + + C + P P + WL++ K + + L + + +L
Sbjct: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
++K P+ G Y N +GE S C+V + + N
Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECS--CQVSLMLQN 744
Score = 32.0 bits (71), Expect = 0.86
Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 4/132 (3%)
Query: 15 LKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQ--TYIRKVGDTVN 72
L ++E P D AG Q + ++E P + + + +G +V
Sbjct: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 670
Query: 73 LLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG 130
+ G P P W DG AL DT V E L +++ Q +G+Y++ ++
Sbjct: 671 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
Query: 131 GLEATATIDILV 142
E + + +++
Sbjct: 731 VGECSCQVSLML 742
Score = 29.3 bits (64), Expect = 5.6
Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTRR--VSVRNGEQDSILFIREAQRADSGRY 123
G V + + G P P+ IW H+G + + G Q S L I+E D+G Y
Sbjct: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS-LCIQEVFPEDTGTY 624
>gi|116008188 myosin light chain kinase isoform 2 [Homo sapiens]
Length = 1845
Score = 63.5 bits (153), Expect = 3e-10
Identities = 36/91 (39%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AP F+ L DC + G + L C VR +P P+I WL N IQ R+ G+ L
Sbjct: 444 APSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQ---YARSTCEAGVAELH 500
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I+ P D G YTC A N LG+ S V V
Sbjct: 501 IQDALPEDHGTYTCLAENALGQVSCSAWVTV 531
Score = 57.8 bits (138), Expect = 1e-08
Identities = 57/219 (26%), Positives = 90/219 (41%), Gaps = 9/219 (4%)
Query: 16 KVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQ---TYIRKVGDTVN 72
++K P + PP A T + P + PK +P + Q + G++V
Sbjct: 1131 EMKSRRPKSSLPPVLGTESDA---TVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1187
Query: 73 LLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGG 131
L G W + ++ + V N E S L I A++ G Y L V+
Sbjct: 1188 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKL 1247
Query: 132 LEATATIDILVIERPGPPQSIKLV-DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSG 190
A +++ V+++P PP D+ S TL W G +A+ Y+++ D+ +
Sbjct: 1248 GSRQAQVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANK 1307
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
W L TS V DL+ + Y FRV A N G SE
Sbjct: 1308 TW-KELATCRSTSFNVQDLLPDHEYKFRVRAINVYGTSE 1345
Score = 54.7 bits (130), Expect = 1e-07
Identities = 34/92 (36%), Positives = 44/92 (47%), Gaps = 2/92 (2%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG-ICSL 318
AP F Q L D G L C V + P IIW N ++ K+ L+ G +CS+
Sbjct: 1028 APAFKQKLQDVHVAEGKKLLLQCQVSSDPPATIIWTLNGKTLK-TTKFIILSQEGSLCSV 1086
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
I K P D G+Y C A N G+A C+V V
Sbjct: 1087 SIEKALPEDRGLYKCVAKNDAGQAECSCQVTV 1118
Score = 52.8 bits (125), Expect = 5e-07
Identities = 33/125 (26%), Positives = 57/125 (45%), Gaps = 1/125 (0%)
Query: 228 SETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRAS 287
S T+P+ + ++ + + A+ P F++ + D V G + C +
Sbjct: 1707 SPTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGY 1766
Query: 288 PRPKIIWLKNKMDIQGNPKYRA-LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDC 346
P P+++W K+ I+ + ++ G CSL I D YTCKAVN LGEA+
Sbjct: 1767 PDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTA 1826
Query: 347 RVDVK 351
+ V+
Sbjct: 1827 ELIVE 1831
Score = 51.6 bits (122), Expect = 1e-06
Identities = 26/91 (28%), Positives = 42/91 (46%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
PKF L G + C + P+P++ WLK + +Q + + G+ LEI
Sbjct: 161 PKFATKLGRVVVKEGQMGRFSCKITGRPQPQVTWLKGNVPLQPSARVSVSEKNGMQVLEI 220
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
D G+YTC VN G+AS+ + ++
Sbjct: 221 HGVNQDDVGVYTCLVVNGSGKASMSAELSIQ 251
Score = 50.8 bits (120), Expect = 2e-06
Identities = 31/95 (32%), Positives = 46/95 (48%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLE 319
AP F Q L+D + G + V +P P++IWL N +IQ + + SL
Sbjct: 553 APIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLC 612
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
I++ P D G YTC+A N GE + V+ P+
Sbjct: 613 IQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPH 647
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/115 (26%), Positives = 44/115 (38%), Gaps = 1/115 (0%)
Query: 238 AHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN 297
+HI K + +EAP F P + G + VR P P++ W +N
Sbjct: 10 SHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRGYPEPQVTWHRN 69
Query: 298 KMDIQGNPKYRALTHL-GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
I ++ + G SL I D G YTC+A N G V + V+
Sbjct: 70 GQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTVE 124
Score = 35.8 bits (81), Expect = 0.060
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 3/95 (3%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN-KMDIQGNPKYRALTHLGICSLE 319
P F T G + + C + P P + WL++ K + + L + + +L
Sbjct: 652 PWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLV 711
Query: 320 IRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
++K P+ G Y N +GE S C+V + + N
Sbjct: 712 LKKVQPWHAGQYEILLKNRVGECS--CQVSLMLQN 744
Score = 32.0 bits (71), Expect = 0.86
Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 4/132 (3%)
Query: 15 LKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQ--TYIRKVGDTVN 72
L ++E P D AG Q + ++E P + + + +G +V
Sbjct: 611 LCIQEVFPEDTGTYTCEAWNSAGEVRTQAVLTVQEPHDGTQPWFISKPRSVTASLGQSVL 670
Query: 73 LLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLG 130
+ G P P W DG AL DT V E L +++ Q +G+Y++ ++
Sbjct: 671 ISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQNEDVFTLVLKKVQPWHAGQYEILLKNR 730
Query: 131 GLEATATIDILV 142
E + + +++
Sbjct: 731 VGECSCQVSLML 742
Score = 29.3 bits (64), Expect = 5.6
Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTRR--VSVRNGEQDSILFIREAQRADSGRY 123
G V + + G P P+ IW H+G + + G Q S L I+E D+G Y
Sbjct: 568 GSQVTMTVQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHS-LCIQEVFPEDTGTY 624
>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
Length = 2986
Score = 62.8 bits (151), Expect = 5e-10
Identities = 66/231 (28%), Positives = 92/231 (39%), Gaps = 16/231 (6%)
Query: 7 PEVAAGSKLKVKEA-SPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIR 65
P+ G+K+ VKE S ++E P P + + P+ +P
Sbjct: 2428 PKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVA--PEFLVPLV---DVTC 2482
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVS----VRNGEQDSI-LFIREAQRAD 119
+GDTV L G+PKP W D LDT S V + + I L I D
Sbjct: 2483 LLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQD 2542
Query: 120 SGRYQLRV--QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTAL 177
SG Y G +AT+ + + P P + S L W PP TGN +
Sbjct: 2543 SGIYTCIATNDHGTTSTSATVKVQGV--PAAPNRPIAQERSCTSVILRWLPPSSTGNCTI 2600
Query: 178 LGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
GYTV+ + S +W + T ++ DL G Y FRV A N G+S
Sbjct: 2601 SGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGIS 2651
Score = 48.5 bits (114), Expect = 9e-06
Identities = 33/97 (34%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC--- 316
AP+F PL D T + G L C V P+P I W +I A + C
Sbjct: 2470 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 2529
Query: 317 --SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
+L+I P D GIYTC A N G S V V+
Sbjct: 2530 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 2566
>gi|68362740 kalirin, RhoGEF kinase isoform 3 [Homo sapiens]
Length = 1289
Score = 62.8 bits (151), Expect = 5e-10
Identities = 66/231 (28%), Positives = 92/231 (39%), Gaps = 16/231 (6%)
Query: 7 PEVAAGSKLKVKEA-SPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIR 65
P+ G+K+ VKE S ++E P P + + P+ +P
Sbjct: 731 PKDILGNKVSVKETNSSEESECDDLDPNTSMEILNPNFIQEVA--PEFLVPLV---DVTC 785
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTH-DGCALDTRRVS----VRNGEQDSI-LFIREAQRAD 119
+GDTV L G+PKP W D LDT S V + + I L I D
Sbjct: 786 LLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQD 845
Query: 120 SGRYQLRV--QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTAL 177
SG Y G +AT+ + + P P + S L W PP TGN +
Sbjct: 846 SGIYTCIATNDHGTTSTSATVKVQGV--PAAPNRPIAQERSCTSVILRWLPPSSTGNCTI 903
Query: 178 LGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLS 228
GYTV+ + S +W + T ++ DL G Y FRV A N G+S
Sbjct: 904 SGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGIS 954
Score = 48.5 bits (114), Expect = 9e-06
Identities = 33/97 (34%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGIC--- 316
AP+F PL D T + G L C V P+P I W +I A + C
Sbjct: 773 APEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSG 832
Query: 317 --SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
+L+I P D GIYTC A N G S V V+
Sbjct: 833 EITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQ 869
>gi|140560917 myomesin 1 isoform b [Homo sapiens]
Length = 1589
Score = 62.0 bits (149), Expect = 8e-10
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 22/201 (10%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV--QKADTKSGLWFTVLEHYHRTS 203
PGPP S+K +V S L+W PP +G T + GY V ++A K W + E +
Sbjct: 943 PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1002
Query: 204 CI-VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+ V L G SY FRV A NQ G+ + +DLA A T TK
Sbjct: 1003 YLKVRGLKEGVSYVFRVRAINQAGVGK----PSDLAGPVVAETRPGTKEVVVN------- 1051
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
D V N F C + +P+ + W K+ + + +P+ + + +
Sbjct: 1052 -----VDDDGVISLN---FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKD 1103
Query: 323 PGPFDGGIYTCKAVNPLGEAS 343
G D GIY+C + G AS
Sbjct: 1104 LGMDDLGIYSCDVTDTDGIAS 1124
Score = 49.7 bits (117), Expect = 4e-06
Identities = 39/172 (22%), Positives = 76/172 (44%), Gaps = 11/172 (6%)
Query: 82 KPQAIWTHDGCALDTRR--VSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATID 139
+P+ W +G L + ++ +GE+ ++ F + D G Y +RV++G +
Sbjct: 438 QPEIQWYRNGVPLSPSKWVQTLWSGERATLTF-SHLNKEDEGLYTIRVRMGEYYEQYSAY 496
Query: 140 ILVIER-------PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
+ V + P P +K ++ + W P G + +LGY + K + + W
Sbjct: 497 VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
Query: 193 FTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
+ + + V+ LI G SY FRV A N+ G+ + ++ +A + A
Sbjct: 557 SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPA 608
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP + + + L W PP G+ ++ Y V+K + + W V S
Sbjct: 638 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
+ DL G SY FRV N G+ E + T
Sbjct: 697 FALFDLAEGKSYCFRVRCSNSAGVGEPSEAT 727
Score = 42.0 bits (97), Expect = 8e-04
Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNK--MDIQGNP-KYRALTHLGIC 316
AP+F T N +L C + P P++ W KN+ +++ NP KY + G+
Sbjct: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
+LEI D Y A+N GE S V VK
Sbjct: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
Score = 33.5 bits (75), Expect = 0.30
Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 12/100 (12%)
Query: 143 IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV---QKADTKSGLW-----FT 194
I P PP I ++ + S L W P G + GY V + D G W
Sbjct: 835 IAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKA 894
Query: 195 VLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
V E ++ S + +++ Y F+V A N GL + ++
Sbjct: 895 VSEEAYKISNLKENMV----YQFQVAAMNMAGLGAPSAVS 930
Score = 33.1 bits (74), Expect = 0.39
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 161 SATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD-LIIGNSYAFRV 219
S + W +D L+GY ++ + SG W + + S L+ G SY FRV
Sbjct: 754 SVVVSWEESKDAKE--LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRV 811
Query: 220 FAENQCGLSE 229
A N GLSE
Sbjct: 812 RAVNAAGLSE 821
Score = 29.6 bits (65), Expect = 4.3
Identities = 24/89 (26%), Positives = 32/89 (35%), Gaps = 2/89 (2%)
Query: 267 LADCTTVT-GYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG-ICSLEIRKPG 324
L D T+ G L C V P P++ WLKN+ + + G I
Sbjct: 1482 LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1541
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D G Y N G + D V V +P
Sbjct: 1542 TADSGKYGLVVKNKYGSETSDFTVSVFIP 1570
>gi|140560919 myomesin 1 isoform a [Homo sapiens]
Length = 1685
Score = 62.0 bits (149), Expect = 8e-10
Identities = 58/201 (28%), Positives = 85/201 (42%), Gaps = 22/201 (10%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV--QKADTKSGLWFTVLEHYHRTS 203
PGPP S+K +V S L+W PP +G T + GY V ++A K W + E +
Sbjct: 1039 PGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNV 1098
Query: 204 CI-VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPK 262
+ V L G SY FRV A NQ G+ + +DLA A T TK
Sbjct: 1099 YLKVRGLKEGVSYVFRVRAINQAGVGK----PSDLAGPVVAETRPGTKEVVVN------- 1147
Query: 263 FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRK 322
D V N F C + +P+ + W K+ + + +P+ + + +
Sbjct: 1148 -----VDDDGVISLN---FECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKD 1199
Query: 323 PGPFDGGIYTCKAVNPLGEAS 343
G D GIY+C + G AS
Sbjct: 1200 LGMDDLGIYSCDVTDTDGIAS 1220
Score = 49.7 bits (117), Expect = 4e-06
Identities = 39/172 (22%), Positives = 76/172 (44%), Gaps = 11/172 (6%)
Query: 82 KPQAIWTHDGCALDTRR--VSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATID 139
+P+ W +G L + ++ +GE+ ++ F + D G Y +RV++G +
Sbjct: 438 QPEIQWYRNGVPLSPSKWVQTLWSGERATLTF-SHLNKEDEGLYTIRVRMGEYYEQYSAY 496
Query: 140 ILVIER-------PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
+ V + P P +K ++ + W P G + +LGY + K + + W
Sbjct: 497 VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556
Query: 193 FTVLEHYHRTSCI-VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
+ + + V+ LI G SY FRV A N+ G+ + ++ +A + A
Sbjct: 557 SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPA 608
Score = 43.5 bits (101), Expect = 3e-04
Identities = 27/91 (29%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTS-- 203
PGPP + + + L W PP G+ ++ Y V+K + + W V S
Sbjct: 638 PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
+ DL G SY FRV N G+ E + T
Sbjct: 697 FALFDLAEGKSYCFRVRCSNSAGVGEPSEAT 727
Score = 42.0 bits (97), Expect = 8e-04
Identities = 30/95 (31%), Positives = 43/95 (45%), Gaps = 3/95 (3%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNK--MDIQGNP-KYRALTHLGIC 316
AP+F T N +L C + P P++ W KN+ +++ NP KY + G+
Sbjct: 276 APEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMH 335
Query: 317 SLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
+LEI D Y A+N GE S V VK
Sbjct: 336 TLEINGCDFEDTAQYRASAMNVKGELSAYASVVVK 370
Score = 33.1 bits (74), Expect = 0.39
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 161 SATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSD-LIIGNSYAFRV 219
S + W +D L+GY ++ + SG W + + S L+ G SY FRV
Sbjct: 754 SVVVSWEESKDAKE--LVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRV 811
Query: 220 FAENQCGLSE 229
A N GLSE
Sbjct: 812 RAVNAAGLSE 821
Score = 33.1 bits (74), Expect = 0.39
Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 12/97 (12%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV---QKADTKSGLW-----FTVLE 197
P PP I ++ + S L W P G + GY V + D G W V E
Sbjct: 934 PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
++ S + +++ Y F+V A N GL + ++
Sbjct: 994 EAYKISNLKENMV----YQFQVAAMNMAGLGAPSAVS 1026
Score = 29.6 bits (65), Expect = 4.3
Identities = 24/89 (26%), Positives = 32/89 (35%), Gaps = 2/89 (2%)
Query: 267 LADCTTVT-GYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLG-ICSLEIRKPG 324
L D T+ G L C V P P++ WLKN+ + + G I
Sbjct: 1578 LPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVS 1637
Query: 325 PFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D G Y N G + D V V +P
Sbjct: 1638 TADSGKYGLVVKNKYGSETSDFTVSVFIP 1666
>gi|155969693 myomesin family, member 3 [Homo sapiens]
Length = 1437
Score = 61.2 bits (147), Expect = 1e-09
Identities = 44/151 (29%), Positives = 68/151 (45%), Gaps = 9/151 (5%)
Query: 87 WTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQ--LGGLEATATIDILVI 143
W DG L +RR + ++ + L + + D G Y +RV G E + + +
Sbjct: 306 WFRDGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRDA 365
Query: 144 ER-----PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH 198
E PG P +++ +DV L W PP DT + YT+++ +SG W E
Sbjct: 366 EAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHEA 425
Query: 199 YHRT-SCIVSDLIIGNSYAFRVFAENQCGLS 228
T C + L+ G SY FRV A ++ G S
Sbjct: 426 PGGTCRCPIQGLVEGQSYRFRVRAISRVGSS 456
Score = 51.6 bits (122), Expect = 1e-06
Identities = 35/110 (31%), Positives = 48/110 (43%), Gaps = 4/110 (3%)
Query: 246 VYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGN- 304
V + K + + P F PL L C V+ASP P++ W KN I
Sbjct: 139 VQEAKELRELCYGRGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRIDPRL 198
Query: 305 ---PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
KYR + G+ SLEIR+ D YT + N G+AS +V V+
Sbjct: 199 FRAGKYRITNNYGLLSLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVR 248
Score = 49.3 bits (116), Expect = 5e-06
Identities = 31/86 (36%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 145 RPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE-HYHRTS 203
+PGPP ++ +V S L+W PP G + GY V + S W V T
Sbjct: 801 QPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTH 860
Query: 204 CIVSDLIIGNSYAFRVFAENQCGLSE 229
VSDL G SY F+V A N GL +
Sbjct: 861 LRVSDLQPGKSYVFQVQAMNSAGLGQ 886
Score = 44.7 bits (104), Expect = 1e-04
Identities = 32/103 (31%), Positives = 46/103 (44%), Gaps = 4/103 (3%)
Query: 131 GLEATATIDILV---IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADT 187
G + AT I V + P P L++ + W PP+ G +LGY + + D+
Sbjct: 682 GESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDS 741
Query: 188 KSGLWFTVLEHYHRTS-CIVSDLIIGNSYAFRVFAENQCGLSE 229
+ W V + T C VSDL G+ Y FR A N G+ E
Sbjct: 742 EELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGE 784
Score = 39.3 bits (90), Expect = 0.005
Identities = 33/117 (28%), Positives = 50/117 (42%), Gaps = 10/117 (8%)
Query: 124 QLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
++ + E T TI P PP ++ ++ L W P + A L Y+++
Sbjct: 486 KITISTDAFEDTVTI-------PSPPTNVHASEIREAYVVLAWEEPSPR-DRAPLTYSLE 537
Query: 184 KADTKSGLWFTVLEHYHRTS--CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
K+ SG W + S V DL SY FRV A NQ GLS+ + + +A
Sbjct: 538 KSVIGSGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIA 594
Score = 36.2 bits (82), Expect = 0.046
Identities = 30/107 (28%), Positives = 43/107 (40%), Gaps = 4/107 (3%)
Query: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH-YHRTSCIV 206
PP ++ S +L W P +D LLGY + + W TV T V
Sbjct: 604 PPAQVQAFRDTQTSVSLTWDPVKDP---ELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTV 660
Query: 207 SDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFA 253
L G Y F V + ++ G+ E++ T + Q AT GFA
Sbjct: 661 PGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFA 707
Score = 34.3 bits (77), Expect = 0.17
Identities = 25/90 (27%), Positives = 34/90 (37%), Gaps = 1/90 (1%)
Query: 262 KFTQPLADCTTVTGYNTQ-LFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
K + L D T+ T L C V P P+I WLKN + +YR ++ I
Sbjct: 1335 KVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITI 1394
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
K D G Y N G + + V
Sbjct: 1395 EKVNSEDSGRYGVFVKNKYGSETGQVTISV 1424
>gi|156104903 myomesin 2 [Homo sapiens]
Length = 1465
Score = 60.8 bits (146), Expect = 2e-09
Identities = 59/227 (25%), Positives = 94/227 (41%), Gaps = 17/227 (7%)
Query: 26 EPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNL-----LIPFQGK 80
E P S G G P ++P H + T+ R+ G+TV L + P +
Sbjct: 253 EEPFRSVGLPIGLPLSSMIP--YTHFDVQFLEKFGVTF-RREGETVTLKCTMLVTPDLKR 309
Query: 81 PKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLR-VQLGGLEATATI 138
+P+A W D L +++ + GE + L + D G Y LR V GG+ +
Sbjct: 310 VQPRAEWYRDDVLLKESKWTKMFFGEGQASLSFSHLHKDDEGLYTLRIVSRGGVSDHSAF 369
Query: 139 ------DILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLW 192
D LV PG P ++ D + W PP T + ++GY V + + + W
Sbjct: 370 LFVRDADPLVTGAPGAPMDLQCHDANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNW 429
Query: 193 FTVLEHYHR-TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLA 238
+ + V+ L G SY FRV A N G+S + ++ +A
Sbjct: 430 VQCNDAPVKICKYPVTGLFEGRSYIFRVRAVNSAGISRPSRVSDAVA 476
Score = 52.8 bits (125), Expect = 5e-07
Identities = 37/119 (31%), Positives = 54/119 (45%), Gaps = 10/119 (8%)
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY 180
G ++ + LE A + PGPP + ++ L W PP G L+ Y
Sbjct: 493 GEKEIAIYQDDLEGDAQV-------PGPPTGVHASEISRNYVVLSWEPPTPRGKDPLM-Y 544
Query: 181 TVQKADTKSGLWFTVLEHYHRTS--CIVSDLIIGNSYAFRVFAENQCGLSETAPITTDL 237
++K+ SG W V S V DL+ G SY FRV + N+ GLSE + IT+ +
Sbjct: 545 FIEKSVVGSGSWQRVNAQTAVRSPRYAVFDLMEGKSYVFRVLSANRHGLSEPSEITSPI 603
Score = 47.4 bits (111), Expect = 2e-05
Identities = 38/132 (28%), Positives = 60/132 (45%), Gaps = 15/132 (11%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
PGP + +V S + W P +G++ + GY V + +G W TV + +
Sbjct: 813 PGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQTTTANRYL 872
Query: 206 -VSDLIIGNSYAFRVFAENQCG-----------LSETAPITTDL-AHIQKAATVYKTKGF 252
VSDL G +Y FRV A N G L E P T ++ A + + +Y GF
Sbjct: 873 KVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDEQGNIY--LGF 930
Query: 253 AQRDFSEAPKFT 264
++ ++A +FT
Sbjct: 931 DCQEMTDASQFT 942
Score = 45.4 bits (106), Expect = 8e-05
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 146 PGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
P P I L++ G S TL W P+ +G + +LGY + K + W V + + +
Sbjct: 711 PSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGYYLDKREVHHKNWHEVNSSPSKPTIL 770
Query: 206 VSD-LIIGNSYAFRVFAENQCGLSE 229
D L G+ Y F++ A N G+ E
Sbjct: 771 TVDGLTEGSLYEFKIAAVNLAGIGE 795
Score = 40.0 bits (92), Expect = 0.003
Identities = 29/106 (27%), Positives = 45/106 (42%), Gaps = 5/106 (4%)
Query: 247 YKTKGFAQRDFSEAPKFTQPLADCTTVT-GYNTQLFCCVRASPRPKIIWLKNKMDIQGNP 305
+K FA+++ + L D T+ G L C V +P P++IW KN DIQ +
Sbjct: 1333 FKAAAFAEKNRG---RLIGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSE 1389
Query: 306 KYRA-LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
+ + S+ I+ D G Y+ N G +D V V
Sbjct: 1390 HFSVKVEQAKYVSMTIKGVTSEDSGKYSINIKNKYGGEKIDVTVSV 1435
Score = 35.0 bits (79), Expect = 0.10
Identities = 28/97 (28%), Positives = 43/97 (44%), Gaps = 3/97 (3%)
Query: 258 SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDI--QGNP-KYRALTHLG 314
S AP+ L T + +L V+ P P + W K+ I P KYR ++ G
Sbjct: 151 SRAPEILVRLRSHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYG 210
Query: 315 ICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVK 351
+ +LEI + D Y+ A N G+ S + V V+
Sbjct: 211 VHTLEINRADFDDTATYSAVATNAHGQVSTNAAVVVR 247
Score = 35.0 bits (79), Expect = 0.10
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 8/89 (8%)
Query: 161 SATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH---YHRTSCIVSDLIIGNSYAF 217
S ++W P+ + LLGY V + LW Y+R +V L G Y F
Sbjct: 627 SVVVQWDRPKHEED--LLGYYVDCCVAGTNLWEPCNHKPIGYNRF--VVHGLTTGEQYIF 682
Query: 218 RVFAENQCGLSETAPITTDLAHIQKAATV 246
RV A N G+SE + +D+ +Q A TV
Sbjct: 683 RVKAVNAVGMSENSQ-ESDVIKVQAALTV 710
Score = 30.4 bits (67), Expect = 2.5
Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 8/94 (8%)
Query: 68 GDTVNLLIPFQGKPKPQAIW-THDGCALDTRRVSVRNGEQDSI-LFIREAQRADSGRYQL 125
G T+NL G P P+ IW +D + SV+ + + + I+ DSG+Y +
Sbjct: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418
Query: 126 RV--QLGGLEATATIDIL----VIERPGPPQSIK 153
+ + GG + T+ + I PPQ K
Sbjct: 1419 NIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452
>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform a [Homo sapiens]
Length = 6620
Score = 60.5 bits (145), Expect = 2e-09
Identities = 48/167 (28%), Positives = 70/167 (41%), Gaps = 10/167 (5%)
Query: 81 PKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATAT 137
P +A W +G A+ D+ +G ++L +R AQ +G V +A A+
Sbjct: 4460 PVGEASWYINGAAVQPDDSDWTVTADGSHHALL-LRSAQPHHAGE----VTFACRDAVAS 4514
Query: 138 IDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE 197
+ V+ P PP+ ++V + TL W P G L GY V+ + +G W E
Sbjct: 4515 ARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHE 4574
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA--PITTDLAHIQK 242
C+V L G +Y FRV A G E P T LA K
Sbjct: 4575 LVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPK 4621
Score = 57.4 bits (137), Expect = 2e-08
Identities = 44/156 (28%), Positives = 72/156 (46%), Gaps = 6/156 (3%)
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR---DFS 258
+S ++D + G+ AF V+ E + + + + I K++ V + G QR
Sbjct: 5954 SSIDLNDQVEGDDRAFEVWQEREDSVRKY--LLQARTAIIKSSWVKEICGIQQRLALPVW 6011
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL-GICS 317
P F + LADCT G +L C V +P+P I W K+ +Q +P + + G C+
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
L + D G Y C A + G S ++ V+VP
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107
Score = 48.5 bits (114), Expect = 9e-06
Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT--HLGICSL 318
P+F + V G + Q C + +P P+I W K+ + K++ L+ G+ L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
IR D G+Y C+ VN LG A + ++ P
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSP 6202
Score = 47.8 bits (112), Expect = 2e-05
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 254 QRDFSEAPKF-TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTH 312
Q FS AP+F T+P A +V G + L C + +P P++ W K++ + ++R
Sbjct: 3 QPQFSGAPRFLTRPKAFVVSV-GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGE--ASVDCRVDVK 351
+ L I D G Y C+A N +GE A+V +VD +
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102
Score = 44.7 bits (104), Expect = 1e-04
Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 4/88 (4%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN--KMDIQGNPKYRALTHLGIC 316
+AP F G C V SPRP + W K+ ++ P+ R + LG
Sbjct: 108 QAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR-VEELGEA 166
Query: 317 S-LEIRKPGPFDGGIYTCKAVNPLGEAS 343
S L IR P DGG Y +A NPLG AS
Sbjct: 167 SALRIRAARPRDGGTYEVRAENPLGAAS 194
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/170 (21%), Positives = 68/170 (40%), Gaps = 20/170 (11%)
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSET-APITTDL--------AHIQKAATVYKTKGF--- 252
I++ ++ + +R AEN G+S T A + DL A ++++ + +G+
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244
Query: 253 -------AQRDFSEAPKFTQPLADCTTVTGYNTQLFCC-VRASPRPKIIWLKNKMDIQGN 304
+ D + P+ + L D G F V+ P P++ W K+ + +
Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTAS 5304
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
R + +LEI D G Y N +G A R+ V+ P+
Sbjct: 5305 AHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD 5354
Score = 39.3 bits (90), Expect = 0.005
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 5/106 (4%)
Query: 240 IQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKM 299
IQ A YK + ++ E P F+ D G +L C V + + WLK+ +
Sbjct: 4879 IQAAFKGYKVRKEMKQQ--EGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGV 4936
Query: 300 DIQGNPKYRALTHLG--ICSLEIRKPGPFDGGIYTCKAVNPLGEAS 343
++ ++ + LG CSL I D G YTC+ N G+ +
Sbjct: 4937 ELTDG-RHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVT 4981
Score = 38.9 bits (89), Expect = 0.007
Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 59 LRQTYIR-KVGDTVNLLIPFQGKPKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIRE 114
LR T IR + G G P+P W+ DG L D RV V + S L IR
Sbjct: 114 LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRA 173
Query: 115 AQRADSGRYQLRVQ--LGGLEATATI 138
A+ D G Y++R + LG A A +
Sbjct: 174 ARPRDGGTYEVRAENPLGAASAAAAL 199
Score = 38.5 bits (88), Expect = 0.009
Identities = 29/120 (24%), Positives = 48/120 (40%), Gaps = 11/120 (9%)
Query: 237 LAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK 296
LAH+Q+ + +G S + CT G + +L C V P+P+ +W K
Sbjct: 220 LAHLQRRREAMRAEGAPASPPSTGTR------TCTVTEGKHARLSCYVTGEPKPETVWKK 273
Query: 297 NKMDIQGNPK---YRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ + + Y + + K D G+YTC A N +G+ V V+ P
Sbjct: 274 DGQLVTEGRRHVVYEDAQENFVLKILFCKQS--DRGLYTCTASNLVGQTYSSVLVVVREP 331
Score = 38.5 bits (88), Expect = 0.009
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 3/94 (3%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA-LTHLGICSL 318
AP F L + GY C V P P + W K+ ++ + Y G L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEAS--VDCRVDV 350
I P D G+Y C A N +G +S + RVD+
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDL 5218
Score = 36.2 bits (82), Expect = 0.046
Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Query: 246 VYKTKGF---AQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDI 301
V+K +G A+ +E P F++PL D T L C + + P + WLK+ +++
Sbjct: 2147 VFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVEL 2205
Query: 302 QGNPKYRALTHLGIC-SLEIRKPGPFDGGIYTCKAVNPLGEASV 344
+ K A+ G C SL I + D G+Y C A + ASV
Sbjct: 2206 RAG-KTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASV 2248
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 245 TVYKTKGFAQRDFSEAPK-FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
TV K++ A+ S+ P T+PL T + L C R +P+ + W K+ +
Sbjct: 2452 TVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSP 2510
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
+ K++ + L I + P D G+Y C+A
Sbjct: 2511 SEKFKMSLEGQMAELRILRLMPADAGVYRCQA 2542
Score = 34.7 bits (78), Expect = 0.13
Identities = 15/51 (29%), Positives = 24/51 (47%)
Query: 283 CVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTC 333
C + P ++W K+ + + + KY L G L + P D G+YTC
Sbjct: 2668 CEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC 2718
Score = 34.3 bits (77), Expect = 0.17
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
+PL D G + +L C + + P + WLK++ I+ + KY + + L IR
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889
Query: 325 PFDGGIYTCKAVNPLGEASV 344
D G YTC+ AS+
Sbjct: 2890 LKDAGEYTCEVEASKSTASL 2909
Score = 33.9 bits (76), Expect = 0.23
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDS---ILFIREAQRADSGRYQ 124
G+ +G P PQ W DG L T E S +L IR A + D G Y+
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181
Query: 125 LRV--QLGGLEATATIDI 140
+ +LG A+A + I
Sbjct: 6182 CELVNRLGSARASAELRI 6199
Score = 33.5 bits (75), Expect = 0.30
Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCA--LDTRRVSVRNGEQDSILFIREAQRADSGRY 123
++G+TV L G PKP W DG A +D + + + + L + DSG+Y
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Score = 32.0 bits (71), Expect = 0.86
Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 79 GKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATA 136
G+PKP+ +W DG + R V + +++ +L I +++D G Y + T
Sbjct: 263 GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTAS-NLVGQTY 321
Query: 137 TIDILVIERPGPPQSIKLVDV 157
+ ++V+ P P +L D+
Sbjct: 322 SSVLVVVREPAVPFKKRLQDL 342
Score = 30.8 bits (68), Expect = 1.9
Identities = 15/58 (25%), Positives = 27/58 (46%)
Query: 278 TQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
T + C A P+ ++ W K+ + + K R L +++ G D G Y+C+A
Sbjct: 1183 TAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240
Score = 30.0 bits (66), Expect = 3.3
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 272 TVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIY 331
T G + L C V A + ++ W K+ + + K R + L +++ G D G Y
Sbjct: 1270 TEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328
Query: 332 TCKAVNPLGEASVDCRVDVKVP 353
TC+A G + +DV P
Sbjct: 1329 TCEA----GGQRLSFHLDVSEP 1346
Score = 30.0 bits (66), Expect = 3.3
Identities = 20/74 (27%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKII-WLKNKMDIQGNPKYRALTHLGICSLE 319
PKF L TG +L C + + ++ WLK +++ PKY + L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 320 IRKPGPFDGGIYTC 333
I + D G Y C
Sbjct: 4128 IHQLEAKDTGEYAC 4141
Score = 29.3 bits (64), Expect = 5.6
Identities = 18/71 (25%), Positives = 27/71 (38%)
Query: 278 TQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVN 337
T CC + + W K + + KY+ + L +R D G YTC +
Sbjct: 3995 TAHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGH 4054
Query: 338 PLGEASVDCRV 348
AS+ RV
Sbjct: 4055 TQSMASLSVRV 4065
Score = 28.9 bits (63), Expect = 7.3
Identities = 18/73 (24%), Positives = 28/73 (38%), Gaps = 1/73 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P F +PL G +T C + P ++W K + +Q N + L +
Sbjct: 3890 PVFREPLQSLQAEEG-STATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948
Query: 321 RKPGPFDGGIYTC 333
+ D G YTC
Sbjct: 3949 QDLQREDTGEYTC 3961
Score = 28.5 bits (62), Expect = 9.5
Identities = 13/42 (30%), Positives = 18/42 (42%)
Query: 292 IIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTC 333
+ WLK+ + PKY G L +R D G+Y C
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778
Score = 28.5 bits (62), Expect = 9.5
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 6/105 (5%)
Query: 233 ITTDLAHIQKAATVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCV-RASPRP 290
+ D IQ A +++ AQ E P +PL D + + L C V RAS +
Sbjct: 2263 LAEDAGEIQFVAENAESR--AQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQV 2320
Query: 291 KIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
+ W K ++Q PKY ++ L I D YTC A
Sbjct: 2321 R--WFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363
>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
RhoGEF isoform b [Homo sapiens]
Length = 7968
Score = 60.5 bits (145), Expect = 2e-09
Identities = 48/167 (28%), Positives = 70/167 (41%), Gaps = 10/167 (5%)
Query: 81 PKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATAT 137
P +A W +G A+ D+ +G ++L +R AQ +G V +A A+
Sbjct: 4460 PVGEASWYINGAAVQPDDSDWTVTADGSHHALL-LRSAQPHHAGE----VTFACRDAVAS 4514
Query: 138 IDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLE 197
+ V+ P PP+ ++V + TL W P G L GY V+ + +G W E
Sbjct: 4515 ARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHE 4574
Query: 198 HYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETA--PITTDLAHIQK 242
C+V L G +Y FRV A G E P T LA K
Sbjct: 4575 LVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTVRLAEPPK 4621
Score = 57.4 bits (137), Expect = 2e-08
Identities = 44/156 (28%), Positives = 72/156 (46%), Gaps = 6/156 (3%)
Query: 202 TSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR---DFS 258
+S ++D + G+ AF V+ E + + + + I K++ V + G QR
Sbjct: 5954 SSIDLNDQVEGDDRAFEVWQEREDSVRKY--LLQARTAIIKSSWVKEICGIQQRLALPVW 6011
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL-GICS 317
P F + LADCT G +L C V +P+P I W K+ +Q +P + + G C+
Sbjct: 6012 RPPDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCA 6071
Query: 318 LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
L + D G Y C A + G S ++ V+VP
Sbjct: 6072 LILDSLTGVDSGQYMCFAASAAGNCSTLGKILVQVP 6107
Score = 48.5 bits (114), Expect = 9e-06
Identities = 27/95 (28%), Positives = 44/95 (46%), Gaps = 2/95 (2%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALT--HLGICSL 318
P+F + V G + Q C + +P P+I W K+ + K++ L+ G+ L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
IR D G+Y C+ VN LG A + ++ P
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQSP 6202
Score = 47.8 bits (112), Expect = 2e-05
Identities = 32/101 (31%), Positives = 51/101 (50%), Gaps = 4/101 (3%)
Query: 254 QRDFSEAPKF-TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTH 312
Q FS AP+F T+P A +V G + L C + +P P++ W K++ + ++R
Sbjct: 3 QPQFSGAPRFLTRPKAFVVSV-GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQD 61
Query: 313 LGICSLEIRKPGPFDGGIYTCKAVNPLGE--ASVDCRVDVK 351
+ L I D G Y C+A N +GE A+V +VD +
Sbjct: 62 GDLYRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQVDAE 102
Score = 44.7 bits (104), Expect = 1e-04
Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 4/88 (4%)
Query: 259 EAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKN--KMDIQGNPKYRALTHLGIC 316
+AP F G C V SPRP + W K+ ++ P+ R + LG
Sbjct: 108 QAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVR-VEELGEA 166
Query: 317 S-LEIRKPGPFDGGIYTCKAVNPLGEAS 343
S L IR P DGG Y +A NPLG AS
Sbjct: 167 SALRIRAARPRDGGTYEVRAENPLGAAS 194
Score = 44.3 bits (103), Expect = 2e-04
Identities = 40/163 (24%), Positives = 61/163 (37%), Gaps = 6/163 (3%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCALD--TRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+G +V L +P QA W+ DG L+ +R + + +L I D G Y
Sbjct: 7476 LGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYT 7535
Query: 125 LRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQK 184
V T T + ERP + +V+ L W P + G Y VQ
Sbjct: 7536 CSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVT---YIVQ- 7591
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGL 227
+ G W T+ + S L G +Y FR ++ G+
Sbjct: 7592 CSLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGM 7634
Score = 40.4 bits (93), Expect = 0.002
Identities = 26/87 (29%), Positives = 39/87 (44%), Gaps = 1/87 (1%)
Query: 255 RDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYR-ALTHL 313
+ + AP F + L+D T V G + L C V A P + W K+ ++ + + + T
Sbjct: 7457 KSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLK 7516
Query: 314 GICSLEIRKPGPFDGGIYTCKAVNPLG 340
L I D G+YTC N LG
Sbjct: 7517 NFQLLTILVVVAEDLGVYTCSVSNALG 7543
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/170 (21%), Positives = 68/170 (40%), Gaps = 20/170 (11%)
Query: 205 IVSDLIIGNSYAFRVFAENQCGLSET-APITTDL--------AHIQKAATVYKTKGF--- 252
I++ ++ + +R AEN G+S T A + DL A ++++ + +G+
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSS 5244
Query: 253 -------AQRDFSEAPKFTQPLADCTTVTGYNTQLFCC-VRASPRPKIIWLKNKMDIQGN 304
+ D + P+ + L D G F V+ P P++ W K+ + +
Sbjct: 5245 REQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTAS 5304
Query: 305 PKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN 354
R + +LEI D G Y N +G A R+ V+ P+
Sbjct: 5305 AHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPD 5354
Score = 40.0 bits (92), Expect = 0.003
Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 2/92 (2%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P + D TG Q + P+P + W K+ + + + + SL +
Sbjct: 6357 PSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVL 6416
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
R D G+YTC A N G+ V C+ ++ V
Sbjct: 6417 RHVASKDAGVYTCLAQNTGGQ--VLCKAELLV 6446
Score = 39.3 bits (90), Expect = 0.005
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 5/106 (4%)
Query: 240 IQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKM 299
IQ A YK + ++ E P F+ D G +L C V + + WLK+ +
Sbjct: 4879 IQAAFKGYKVRKEMKQQ--EGPMFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGV 4936
Query: 300 DIQGNPKYRALTHLG--ICSLEIRKPGPFDGGIYTCKAVNPLGEAS 343
++ ++ + LG CSL I D G YTC+ N G+ +
Sbjct: 4937 ELTDG-RHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQVT 4981
Score = 38.9 bits (89), Expect = 0.007
Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 6/86 (6%)
Query: 59 LRQTYIR-KVGDTVNLLIPFQGKPKPQAIWTHDGCAL---DTRRVSVRNGEQDSILFIRE 114
LR T IR + G G P+P W+ DG L D RV V + S L IR
Sbjct: 114 LRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEASALRIRA 173
Query: 115 AQRADSGRYQLRVQ--LGGLEATATI 138
A+ D G Y++R + LG A A +
Sbjct: 174 ARPRDGGTYEVRAENPLGAASAAAAL 199
Score = 38.5 bits (88), Expect = 0.009
Identities = 29/120 (24%), Positives = 48/120 (40%), Gaps = 11/120 (9%)
Query: 237 LAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK 296
LAH+Q+ + +G S + CT G + +L C V P+P+ +W K
Sbjct: 220 LAHLQRRREAMRAEGAPASPPSTGTR------TCTVTEGKHARLSCYVTGEPKPETVWKK 273
Query: 297 NKMDIQGNPK---YRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ + + Y + + K D G+YTC A N +G+ V V+ P
Sbjct: 274 DGQLVTEGRRHVVYEDAQENFVLKILFCKQS--DRGLYTCTASNLVGQTYSSVLVVVREP 331
Score = 38.5 bits (88), Expect = 0.009
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 3/94 (3%)
Query: 260 APKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA-LTHLGICSL 318
AP F L + GY C V P P + W K+ ++ + Y G L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184
Query: 319 EIRKPGPFDGGIYTCKAVNPLGEAS--VDCRVDV 350
I P D G+Y C A N +G +S + RVD+
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRVDL 5218
Score = 36.2 bits (82), Expect = 0.046
Identities = 32/104 (30%), Positives = 50/104 (48%), Gaps = 7/104 (6%)
Query: 246 VYKTKGF---AQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDI 301
V+K +G A+ +E P F++PL D T L C + + P + WLK+ +++
Sbjct: 2147 VFKAEGVHTSARLVVTELPVSFSRPLQDVVTTEKEKVTLECEL-SRPNVDVRWLKDGVEL 2205
Query: 302 QGNPKYRALTHLGIC-SLEIRKPGPFDGGIYTCKAVNPLGEASV 344
+ K A+ G C SL I + D G+Y C A + ASV
Sbjct: 2206 RAG-KTMAIAAQGACRSLTIYRCEFADQGVYVCDAHDAQSSASV 2248
Score = 34.7 bits (78), Expect = 0.13
Identities = 25/92 (27%), Positives = 43/92 (46%), Gaps = 2/92 (2%)
Query: 245 TVYKTKGFAQRDFSEAPK-FTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
TV K++ A+ S+ P T+PL T + L C R +P+ + W K+ +
Sbjct: 2452 TVGKSRSSARLVVSDIPVVLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSP 2510
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
+ K++ + L I + P D G+Y C+A
Sbjct: 2511 SEKFKMSLEGQMAELRILRLMPADAGVYRCQA 2542
Score = 34.7 bits (78), Expect = 0.13
Identities = 15/51 (29%), Positives = 24/51 (47%)
Query: 283 CVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTC 333
C + P ++W K+ + + + KY L G L + P D G+YTC
Sbjct: 2668 CEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC 2718
Score = 34.3 bits (77), Expect = 0.17
Identities = 23/80 (28%), Positives = 37/80 (46%), Gaps = 1/80 (1%)
Query: 265 QPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG 324
+PL D G + +L C + + P + WLK++ I+ + KY + + L IR
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889
Query: 325 PFDGGIYTCKAVNPLGEASV 344
D G YTC+ AS+
Sbjct: 2890 LKDAGEYTCEVEASKSTASL 2909
Score = 33.9 bits (76), Expect = 0.23
Identities = 24/78 (30%), Positives = 33/78 (42%), Gaps = 5/78 (6%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDS---ILFIREAQRADSGRYQ 124
G+ +G P PQ W DG L T E S +L IR A + D G Y+
Sbjct: 6122 GEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYE 6181
Query: 125 LRV--QLGGLEATATIDI 140
+ +LG A+A + I
Sbjct: 6182 CELVNRLGSARASAELRI 6199
Score = 33.9 bits (76), Expect = 0.23
Identities = 23/89 (25%), Positives = 35/89 (39%), Gaps = 1/89 (1%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQ 124
+ G T +G P+P W D L D+ R+S + L +R D+G Y
Sbjct: 6369 QTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAGVYT 6428
Query: 125 LRVQLGGLEATATIDILVIERPGPPQSIK 153
Q G + ++LV+ P S K
Sbjct: 6429 CLAQNTGGQVLCKAELLVLGGDNEPDSEK 6457
Score = 33.5 bits (75), Expect = 0.30
Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 2/60 (3%)
Query: 66 KVGDTVNLLIPFQGKPKPQAIWTHDGCA--LDTRRVSVRNGEQDSILFIREAQRADSGRY 123
++G+TV L G PKP W DG A +D + + + + L + DSG+Y
Sbjct: 6026 ELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085
Score = 32.0 bits (71), Expect = 0.86
Identities = 20/81 (24%), Positives = 39/81 (48%), Gaps = 3/81 (3%)
Query: 79 GKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATA 136
G+PKP+ +W DG + R V + +++ +L I +++D G Y + T
Sbjct: 263 GEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTAS-NLVGQTY 321
Query: 137 TIDILVIERPGPPQSIKLVDV 157
+ ++V+ P P +L D+
Sbjct: 322 SSVLVVVREPAVPFKKRLQDL 342
Score = 30.8 bits (68), Expect = 1.9
Identities = 15/58 (25%), Positives = 27/58 (46%)
Query: 278 TQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
T + C A P+ ++ W K+ + + K R L +++ G D G Y+C+A
Sbjct: 1183 TAMLSCEVAQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEA 1240
Score = 30.0 bits (66), Expect = 3.3
Identities = 22/82 (26%), Positives = 36/82 (43%), Gaps = 5/82 (6%)
Query: 272 TVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIY 331
T G + L C V A + ++ W K+ + + K R + L +++ G D G Y
Sbjct: 1270 TEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEY 1328
Query: 332 TCKAVNPLGEASVDCRVDVKVP 353
TC+A G + +DV P
Sbjct: 1329 TCEA----GGQRLSFHLDVSEP 1346
Score = 30.0 bits (66), Expect = 3.3
Identities = 20/74 (27%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKII-WLKNKMDIQGNPKYRALTHLGICSLE 319
PKF L TG +L C + + ++ WLK +++ PKY + L
Sbjct: 4068 PKFKTRLQSLEQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELL 4127
Query: 320 IRKPGPFDGGIYTC 333
I + D G Y C
Sbjct: 4128 IHQLEAKDTGEYAC 4141
Score = 29.3 bits (64), Expect = 5.6
Identities = 18/71 (25%), Positives = 27/71 (38%)
Query: 278 TQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVN 337
T CC + + W K + + KY+ + L +R D G YTC +
Sbjct: 3995 TAHLCCELSRAGASVEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDYTCDTGH 4054
Query: 338 PLGEASVDCRV 348
AS+ RV
Sbjct: 4055 TQSMASLSVRV 4065
Score = 28.9 bits (63), Expect = 7.3
Identities = 18/73 (24%), Positives = 28/73 (38%), Gaps = 1/73 (1%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P F +PL G +T C + P ++W K + +Q N + L +
Sbjct: 3890 PVFREPLQSLQAEEG-STATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVL 3948
Query: 321 RKPGPFDGGIYTC 333
+ D G YTC
Sbjct: 3949 QDLQREDTGEYTC 3961
Score = 28.5 bits (62), Expect = 9.5
Identities = 13/42 (30%), Positives = 18/42 (42%)
Query: 292 IIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTC 333
+ WLK+ + PKY G L +R D G+Y C
Sbjct: 737 VTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYEC 778
Score = 28.5 bits (62), Expect = 9.5
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 6/105 (5%)
Query: 233 ITTDLAHIQKAATVYKTKGFAQRDFSEAP-KFTQPLADCTTVTGYNTQLFCCV-RASPRP 290
+ D IQ A +++ AQ E P +PL D + + L C V RAS +
Sbjct: 2263 LAEDAGEIQFVAENAESR--AQLRVKELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQV 2320
Query: 291 KIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKA 335
+ W K ++Q PKY ++ L I D YTC A
Sbjct: 2321 R--WFKGSQELQPGPKYELVSDGLYRKLIISDVHAEDEDTYTCDA 2363
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 58.5 bits (140), Expect = 9e-09
Identities = 49/175 (28%), Positives = 79/175 (45%), Gaps = 14/175 (8%)
Query: 67 VGDTVNLLIPFQGKPKPQAI--WTHDGCALDTRRVSVR----NGEQDSILFIREAQRADS 120
VG++V L Q P I W +G D ++ G L IR Q S
Sbjct: 513 VGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHS 572
Query: 121 GRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGY 180
G+Y VQ G ++ D++V PGPP+++K+ ++ +A L W +D ++ ++ Y
Sbjct: 573 GKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKD-NHSPVISY 631
Query: 181 TVQKADTKSGLWFT------VLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
++Q S W T V++ T+ +V +L Y FRV A N+ G E
Sbjct: 632 SIQARTPFSVGWQTVTTVPEVIDGKTHTATVV-ELNPWVEYEFRVVASNKIGGGE 685
Score = 50.4 bits (119), Expect = 2e-06
Identities = 79/330 (23%), Positives = 125/330 (37%), Gaps = 52/330 (15%)
Query: 37 GSPTPQLLPPI----EEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGC 92
GSPTP +L E PKI + +T G TV L G P PQ W
Sbjct: 209 GSPTPLVLRSDGVMGEYEPKIEVQ--FPETLPAAKGSTVKLECFALGNPIPQINWRRSDG 266
Query: 93 ALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSI 152
+ ++ +R + +L I Q+ D+G Y+ + + A + +P Q I
Sbjct: 267 LPFSSKIKLR--KFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLI 324
Query: 153 KLVDV-------WGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCI 205
K V++ W A+ + P ++ ++G +
Sbjct: 325 KDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENG------------ALT 372
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAP--KF 263
+S+L + +S F+ AEN+ GL ++ A ++ A+ DFS+ P K
Sbjct: 373 ISNLSVTDSGMFQCIAENKHGLVYSS------AELKVVASA--------PDFSKNPMKKL 418
Query: 264 TQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKP 323
Q G L C RASPR W K + +Q + + L G+ + K
Sbjct: 419 VQ------VQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKA 472
Query: 324 GPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D G YTC A N G+A+ + V P
Sbjct: 473 ---DAGTYTCMAENQFGKANGTTHLVVTEP 499
Score = 30.8 bits (68), Expect = 1.9
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)
Query: 280 LFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPG-PFDGGIYTCKAVNP 338
L C R +P P W N DI + ++R + G +L + P +D G Y C A N
Sbjct: 48 LHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGG--NLVVINPNRNWDTGTYQCFATNS 105
Query: 339 LG 340
LG
Sbjct: 106 LG 107
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 57.8 bits (138), Expect = 1e-08
Identities = 86/367 (23%), Positives = 135/367 (36%), Gaps = 52/367 (14%)
Query: 2 EAATAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQ 61
E++T V G LK+ A+P DA AG+ + P I +
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTI-----IGT 1457
Query: 62 TYIRKVGDTVN----LLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQR 117
+ +V +N L +G P P W DG L +V ++ +L ++ A+R
Sbjct: 1458 NFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARR 1517
Query: 118 ADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTAL 177
D GRYQ V + I + + P SIK G + T T + L
Sbjct: 1518 NDKGRYQCTVSNAAGKQAKDIKLTIYI----PPSIK-----GGNVT--------TDISVL 1560
Query: 178 LGYTVQKADTKSGLWFTVLEHYHRTSCIVSD---LIIGNSYAFRVFAENQCGLSETAPIT 234
+ ++ GL + Y I+S L I + + +S++A T
Sbjct: 1561 INSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHI---PRAQVSDSATYT 1617
Query: 235 TDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQ--------LFCCVRA 286
+A++ G A++ F + P+ + T N Q L C
Sbjct: 1618 CHVANVA---------GTAEKSF-HVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAG 1667
Query: 287 SPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDC 346
+P P + WLK+ + ++ N R G LEI D G Y C A + GE +
Sbjct: 1668 NPSPILTWLKDGVPVKANDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKY 1725
Query: 347 RVDVKVP 353
VDV VP
Sbjct: 1726 EVDVLVP 1732
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/148 (23%), Positives = 65/148 (43%), Gaps = 2/148 (1%)
Query: 206 VSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQ 265
V+D+ I S+ +R+ ++ + AP + + + K + + EAPK
Sbjct: 647 VNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMV 706
Query: 266 PLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGP 325
++ G T + C P P++ W K ++++ + LG+ L+I++
Sbjct: 707 VQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGL--LKIQETQD 764
Query: 326 FDGGIYTCKAVNPLGEASVDCRVDVKVP 353
D G YTC A+N G A+ +DV P
Sbjct: 765 LDAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 48.1 bits (113), Expect = 1e-05
Identities = 81/350 (23%), Positives = 126/350 (36%), Gaps = 47/350 (13%)
Query: 11 AGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIW-LPRALRQTYIRKVGD 69
A L++K DA GS + ++E PK+ +P+ Q++ G
Sbjct: 572 ANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK--NQSFTG--GS 627
Query: 70 TVNLLIPFQGKPKPQAIWT-HDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQ 128
V+++ G PKP+ WT +D + + R + + D LFI+ A D+G Y
Sbjct: 628 EVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTS---DGTLFIKNAAPKDAGIYGCLAS 684
Query: 129 LGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTK 188
+ IE P KL+ V Q AL TV + T
Sbjct: 685 NSAGTDKQNSTLRYIEAP------KLMVV------------QSELLVALGDITVMECKT- 725
Query: 189 SGL------WFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQK 242
SG+ WF ++ ++ D ++G + ET +
Sbjct: 726 SGIPPPQVKWFKGDLELRPSTFLIIDPLLG-----------LLKIQETQDLDAGDYTCVA 774
Query: 243 AATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLK-NKMDI 301
+ G D P F Q AD + G N L C V+ P P I W + + M I
Sbjct: 775 INEAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPI 834
Query: 302 QGNP-KYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDV 350
P +++ L +L I D G Y C+A N G+ + V V
Sbjct: 835 FSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTV 884
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/76 (32%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 278 TQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVN 337
T LFC V +P P I+W K+ + + + + + + I L++ + P D G Y+CKA+N
Sbjct: 1378 TNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKI--LKLFRATPEDAGRYSCKAIN 1435
Query: 338 PLGEASVDCRVDVKVP 353
G + +DV VP
Sbjct: 1436 IAGTSQKYFNIDVLVP 1451
Score = 45.1 bits (105), Expect = 1e-04
Identities = 37/110 (33%), Positives = 51/110 (46%), Gaps = 7/110 (6%)
Query: 249 TKGFAQRDFS----EAPKFTQPLADCTTVTGYN-TQLFCCVRASPRPKIIWLKNKMDIQG 303
T G A++ F+ P P ++ TV N L C V P P + WLKN+ I+
Sbjct: 2948 TAGSAKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL 3007
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
N L G +L+I + DGG YTC A+N GE+ + V VP
Sbjct: 3008 NTN--TLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVP 3055
Score = 43.9 bits (102), Expect = 2e-04
Identities = 65/282 (23%), Positives = 98/282 (34%), Gaps = 37/282 (13%)
Query: 79 GKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATI 138
G P P W D ++T + +++ +L I + D+GRY E I
Sbjct: 1852 GIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHI 1911
Query: 139 DILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEH 198
+ V E P + K+++ T L+ VQ +G V+
Sbjct: 1912 QLHVHEPPSLEDAGKMLN-----------------ETVLVSNPVQLECKAAGNPVPVITW 1954
Query: 199 YHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYK---TKGFAQR 255
Y + ++ S + Q E+A I+ A I K + T+ F
Sbjct: 1955 YK------DNRLLSGSTSMTFLNRGQIIDIESAQISD--AGIYKCVAINSAGATELFYSL 2006
Query: 256 DFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGI 315
AP + V +L C R P P + WLK+ G+P L +
Sbjct: 2007 QVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKD-----GSPVSSFSNGLQV 2061
Query: 316 CS----LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
S L + D G YTC AVN GE D + V VP
Sbjct: 2062 LSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVP 2103
Score = 42.7 bits (99), Expect = 5e-04
Identities = 25/74 (33%), Positives = 31/74 (41%)
Query: 268 ADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFD 327
+D + + G N +L C P P I WLK+ I R +L I D
Sbjct: 3254 SDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSD 3313
Query: 328 GGIYTCKAVNPLGE 341
G YTC A NP GE
Sbjct: 3314 TGKYTCVATNPAGE 3327
Score = 41.6 bits (96), Expect = 0.001
Identities = 27/74 (36%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 280 LFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPL 339
L+C A+P P + W K+ + + K L G L+I + D G YTC AVN
Sbjct: 2797 LYCETNAAPPPTLTWYKDGHPLTSSDKVLILP--GGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 340 GEASVDCRVDVKVP 353
GE S+ V V VP
Sbjct: 2855 GEDSLQYDVRVLVP 2868
Score = 41.6 bits (96), Expect = 0.001
Identities = 74/287 (25%), Positives = 102/287 (35%), Gaps = 46/287 (16%)
Query: 79 GKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATA 136
G P P+ W DG L D + NG IL I Q D GRY + A
Sbjct: 2898 GSPAPRNSWQKDGQPLLEDDHHKFLSNGR---ILQILNTQITDIGRYVCVAENTAGSAKK 2954
Query: 137 TIDILVIERP---GPPQSIKLVDVWGF-SATLEWT--PPQDTGNTALLGYTVQKADTKSG 190
++ V P GP V V F S T E + PP D L + + K
Sbjct: 2955 YFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPD------LSWLKNEQPIKLN 3008
Query: 191 LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTK 250
++ I + + G Y A NQ G S+ + + TVY
Sbjct: 3009 TNTLIVPGGRTLQIIRAKVSDGGEYT--CIAINQAGESKK----------KFSLTVYVPP 3056
Query: 251 GFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRAL 310
D ++ L+ G + L C A P P I W KN I +
Sbjct: 3057 SIKDHD-------SESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITES------ 3103
Query: 311 THLGICS----LEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
TH+ I + L I+K D G Y C+A+N G + ++V VP
Sbjct: 3104 THVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVP 3150
Score = 41.2 bits (95), Expect = 0.001
Identities = 69/280 (24%), Positives = 103/280 (36%), Gaps = 30/280 (10%)
Query: 79 GKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQ--LGGLEAT 135
G P P+ W + L ++VR+ D L I Q D G Y G T
Sbjct: 916 GNPIPERRWIKNSAMLLQNPYITVRS---DGSLHIERVQLQDGGEYTCVASNVAGTNNKT 972
Query: 136 ATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV 195
++ + V+ Q I L + G TL P + +GN S +W
Sbjct: 973 TSVVVHVLPTIQHGQQI-LSTIEGIPVTL---PCKASGNPK-----------PSVIWSKK 1017
Query: 196 LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQR 255
E +S S G+ Y E TA T A + TVY R
Sbjct: 1018 GELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVY----VRPR 1073
Query: 256 DFSEAPKFTQPL-ADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG-NPKYRALTHL 313
F + +Q + + + G L C V++ P P I W K I +P++ T L
Sbjct: 1074 VFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRH---TFL 1130
Query: 314 GICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
S++I + D G+Y C A N G + +++V VP
Sbjct: 1131 PSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVP 1170
Score = 40.4 bits (93), Expect = 0.002
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 269 DCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDG 328
D T + L C A P P I WL+N +Q P+ R L+ G L+I D
Sbjct: 3630 DITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILS--GGRYLQINNADLGDT 3687
Query: 329 GIYTCKAVNPLGEASVDCRVDVKVP 353
YTC A N G+ + + + V VP
Sbjct: 3688 ANYTCVASNIAGKTTREFILTVNVP 3712
Score = 40.0 bits (92), Expect = 0.003
Identities = 63/289 (21%), Positives = 106/289 (36%), Gaps = 44/289 (15%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCAL---DTRRVSVR-NGEQDSILFIREAQRADSGR 122
+G+ V L+ G P P W DG + +T R+ V NG S L I A +D+G+
Sbjct: 3260 LGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANG---STLNIYGALTSDTGK 3316
Query: 123 YQLRVQLGGLEATATIDILVIERP----GPPQSIKLVDVWGFSATLEW----TPPQDTGN 174
Y E ++ V P ++ KL+ + S +E TPP
Sbjct: 3317 YTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPP---- 3372
Query: 175 TALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPIT 234
Q K+GL + H ++ R+ ++ +
Sbjct: 3373 --------QINWLKNGLPLPLSSHIR---------LLAAGQVIRIVRAQVSDVAVYTCVA 3415
Query: 235 TDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIW 294
++ A + Y + FA + + + T + G +T + C +P P + W
Sbjct: 3416 SNRAGVDNKH--YNLQVFAPPNMDNS----MGTEEITVLKGSSTSMACITDGTPAPSMAW 3469
Query: 295 LKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEAS 343
L++ + + TH + L++ K D G YTC A N GE S
Sbjct: 3470 LRDGQPLGLDAHLTVSTHGMV--LQLLKAETEDSGKYTCIASNEAGEVS 3516
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 282 CCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
C + +P+P I WL N ++ G ++ G L I P+D G Y C AVN G
Sbjct: 1288 CPAKGTPKPTIKWLHNGRELTGREPGISILEDGTL-LVIASVTPYDNGEYICVAVNEAGT 1346
Query: 342 ASVDCRVDVKVP 353
+ V VP
Sbjct: 1347 TERKYNLKVHVP 1358
Score = 39.3 bits (90), Expect = 0.005
Identities = 28/111 (25%), Positives = 48/111 (43%), Gaps = 2/111 (1%)
Query: 15 LKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIW-LPRALRQTYIRKVGDT-VN 72
L + +A+P+DA AG+ ++ ++E P + L T+ +V + +
Sbjct: 1226 LSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 73 LLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRY 123
P +G PKP W H+G L R + E ++L I D+G Y
Sbjct: 1286 FPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEY 1336
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/74 (32%), Positives = 32/74 (43%)
Query: 280 LFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPL 339
L C P P I WLKN I+ + G L+I + D G YTC A N
Sbjct: 3171 LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNME 3230
Query: 340 GEASVDCRVDVKVP 353
G+A + ++VP
Sbjct: 3231 GKAQKYYFLSIQVP 3244
Score = 38.9 bits (89), Expect = 0.007
Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 280 LFCCVRASPRPKIIWLKNKMDI---QGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAV 336
L C P P I WLK+ + QGN K ++ + L+I K D G YTC A
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRV----LQIAKTLLEDAGRYTCVAT 1901
Query: 337 NPLGEASVDCRVDVKVP 353
N GE ++ V P
Sbjct: 1902 NAAGETQQHIQLHVHEP 1918
Score = 38.9 bits (89), Expect = 0.007
Identities = 59/289 (20%), Positives = 99/289 (34%), Gaps = 28/289 (9%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLR 126
V + V L +G P P W DG + + ++ IL + AQ +D+GRY
Sbjct: 2025 VNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCV 2084
Query: 127 VQLGGLEATATIDILVIERP---GPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ 183
E ID+ V P G Q++ ++ S +E D L +
Sbjct: 2085 AVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVL----ISQAVELLCQSDAIPPPTLTWLKD 2140
Query: 184 KADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKA 243
++ E+ R+ + D + ++ + A N G +E
Sbjct: 2141 GHPLLKKPGLSISEN--RSVLKIEDAQVQDTGRYTCEATNVAGKTEKN------------ 2186
Query: 244 ATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQG 303
Y + + + + TQ T + G L C P P +IW K +
Sbjct: 2187 ---YNVNIWVPPNIGGSDELTQ----LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLT 2239
Query: 304 NPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
+ R G L+I D +Y+C A N G A + + V +
Sbjct: 2240 DSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYI 2288
Score = 38.9 bits (89), Expect = 0.007
Identities = 26/74 (35%), Positives = 34/74 (45%), Gaps = 3/74 (4%)
Query: 280 LFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPL 339
L C P P I W K+ I + + R L+ SL+I P D G YTC A N
Sbjct: 4098 LSCEADGLPPPDITWHKDGRAIVESIRQRVLSS---GSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 340 GEASVDCRVDVKVP 353
G +S ++ V VP
Sbjct: 4155 GSSSTSTKLTVHVP 4168
Score = 38.1 bits (87), Expect = 0.012
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 2/75 (2%)
Query: 279 QLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNP 338
+L C V SP P I+WLK+ I ++ L L L I + + G+Y C A N
Sbjct: 1753 ELDCHVTGSPPPTIMWLKDGQLIDERDGFKIL--LNGRKLVIAQAQVSNTGLYRCMAANT 1810
Query: 339 LGEASVDCRVDVKVP 353
G+ + V V VP
Sbjct: 1811 AGDHKKEFEVTVHVP 1825
Score = 38.1 bits (87), Expect = 0.012
Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 2/72 (2%)
Query: 282 CCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
C +P P I W K +++ + + A+ G L+I + D G Y C A NP G
Sbjct: 4009 CEATGTPSPFITWQKEGINVNTSGRNHAVLPSG--GLQISRAVREDAGTYMCVAQNPAGT 4066
Query: 342 ASVDCRVDVKVP 353
A +++V+VP
Sbjct: 4067 ALGKIKLNVQVP 4078
Score = 37.0 bits (84), Expect = 0.027
Identities = 59/286 (20%), Positives = 90/286 (31%), Gaps = 19/286 (6%)
Query: 68 GDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRV 127
G V L G PKP IW+ G + T G D L++ +SG Y
Sbjct: 995 GIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGA-DGSLYVVSPGGEESGEYVCTA 1053
Query: 128 QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADT 187
A + + V RP V+G L P + + L G V
Sbjct: 1054 TNTAGYAKRKVQLTVYVRPR---------VFGDQRGLSQDKPVEI--SVLAGEEVTLPCE 1102
Query: 188 KSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVY 247
L ++ T LI S ++ET + +
Sbjct: 1103 VKSLPPPIITWAKETQ-----LISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAG 1157
Query: 248 KTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKY 307
+ + PK + G + C + +P P I W K + + ++
Sbjct: 1158 NVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEH 1217
Query: 308 RALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
G +L I + P D GIYTC A N G + + V+ P
Sbjct: 1218 HVSNPDG--TLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEP 1261
Score = 37.0 bits (84), Expect = 0.027
Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 2/85 (2%)
Query: 269 DCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDG 328
D T + T L C + P I W K+ ++ N R L G +L+I +
Sbjct: 2584 DVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILP--GGRTLQILNAQEDNA 2641
Query: 329 GIYTCKAVNPLGEASVDCRVDVKVP 353
G Y+C A N GE V V +P
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIP 2666
Score = 36.6 bits (83), Expect = 0.035
Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 3/66 (4%)
Query: 275 GYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCK 334
G N L C V+ P P I W + +DI+ + + R LG SL I D G YTC
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIR---QLGNGSLAIYGTVNEDAGDYTCV 4420
Query: 335 AVNPLG 340
A N G
Sbjct: 4421 ATNEAG 4426
Score = 36.2 bits (82), Expect = 0.046
Identities = 24/93 (25%), Positives = 33/93 (35%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P + T + T L C P+P I W KN + + + L SL I
Sbjct: 3804 PSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVI 3863
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
P D Y C N G+ + V+VP
Sbjct: 3864 ISPSVDDTATYECTVTNGAGDDKRTVDLTVQVP 3896
Score = 35.8 bits (81), Expect = 0.060
Identities = 78/359 (21%), Positives = 132/359 (36%), Gaps = 52/359 (14%)
Query: 9 VAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVG 68
++ G +L++ A +DA AG+ + + P I + I G
Sbjct: 2248 LSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRG 2307
Query: 69 DTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQ-LRV 127
+++L QG P P W DG L + V ++ IL ++ +D+GRY + V
Sbjct: 2308 KSISLECEVQGIPPPTVTWMKDGHPL-IKAKGVEILDEGHILQLKNIHVSDTGRYVCVAV 2366
Query: 128 QLGGL-----EATATIDILVIERPGPPQSIKLVDVWGFSATLEWTP-PQDTGNTALLGYT 181
+ G+ + + +I P++I +V+ S T E + P + G+
Sbjct: 2367 NVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWP 2426
Query: 182 VQKADT---KSG-----LWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPI 233
V +++ SG L T +E + +C+V + F GLS P
Sbjct: 2427 VSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIF--------GLSVLVP- 2477
Query: 234 TTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKII 293
HI T L D + L C V +P P+I
Sbjct: 2478 ----PHIVGENT---------------------LEDVKVKEKQSVTLTCEVTGNPVPEIT 2512
Query: 294 WLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKV 352
W K+ +Q + + ++ G L+I G YTC A +P G S ++V V
Sbjct: 2513 WHKDGQPLQEDEAHHIIS--GGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFV 2569
Score = 35.4 bits (80), Expect = 0.078
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 279 QLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNP 338
+L C A P P + WLK+ + P + + L+I D G YTC+A N
Sbjct: 2122 ELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSV--LKIEDAQVQDTGRYTCEATNV 2179
Query: 339 LGEASVDCRVDVKVP 353
G+ + V++ VP
Sbjct: 2180 AGKTEKNYNVNIWVP 2194
Score = 35.4 bits (80), Expect = 0.078
Identities = 67/293 (22%), Positives = 98/293 (33%), Gaps = 37/293 (12%)
Query: 67 VGDTVNLLIPFQGKPKPQAIWTHDGCAL-DTRRVSVRNGEQDSILFIREAQRADSGRYQL 125
V + + L G P P+ W DG L T +V G + +L I AQ D+GRY
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTLGGGE--VLRISTAQVEDTGRYTC 3599
Query: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQ-K 184
D + R P +I D P+D T++ K
Sbjct: 3600 LAS----SPAGDDDKEYLVRVHVPPNIAGTD-----------EPRDITVLRNRQVTLECK 3644
Query: 185 ADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAA 244
+D T L + R I+ ++ N L +TA T ++I
Sbjct: 3645 SDAVPPPVITWLRNGERLQATPRVRILSGGRYLQI---NNADLGDTANYTCVASNIAGKT 3701
Query: 245 TVYKTKGFAQRDF----SEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMD 300
T R+F + P + +T L C P P+I W K+
Sbjct: 3702 T---------REFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAV 3752
Query: 301 IQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ GN ++ G L I+ D G Y C A N G + V VP
Sbjct: 3753 LAGNHARYSILENGF--LHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVP 3803
Score = 34.7 bits (78), Expect = 0.13
Identities = 74/353 (20%), Positives = 120/353 (33%), Gaps = 36/353 (10%)
Query: 9 VAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVG 68
+A G L +K+A +D AG + P I P R+ + +
Sbjct: 3109 LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPE--REVIVETIS 3166
Query: 69 DTVNLLIPFQGKPKPQAIWTHDGCALDTR-RVSVRNGEQDSILFIREAQRADSGRYQLRV 127
+ V L G P P W + ++ + VR S L I +Q +DSG Y
Sbjct: 3167 NPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTC-- 3224
Query: 128 QLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADT 187
+ G Q + + + P D + LLG V+
Sbjct: 3225 -------------IASNMEGKAQKYYFLSIQVPPSVAGAEIPSDV--SVLLGENVELVCN 3269
Query: 188 KSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVY 247
+G+ +++ I S G + RV A N L+ +T+D AT
Sbjct: 3270 ANGIPTPLIQWLKDGKPIAS----GETERIRVSA-NGSTLNIYGALTSDTGKYTCVAT-- 3322
Query: 248 KTKGFAQRDFSEAPKFTQPLAD-------CTTVTGYNTQLFCCVRASPRPKIIWLKNKMD 300
G R F+ T + T+ + + C +P P+I WLKN +
Sbjct: 3323 NPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINWLKNGLP 3382
Query: 301 IQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ + R L + + I + D +YTC A N G + + V P
Sbjct: 3383 LPLSSHIRLLAAGQV--IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAP 3433
Score = 34.3 bits (77), Expect = 0.17
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 4/93 (4%)
Query: 261 PKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEI 320
P FT+ D + G +L C P PK+ W N I + + ++ G L I
Sbjct: 4260 PTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNIIPAH--FDSVN--GHSELVI 4315
Query: 321 RKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
+ D G Y C A N +G V VK P
Sbjct: 4316 ERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 33.9 bits (76), Expect = 0.23
Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 10/78 (12%)
Query: 280 LFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICS----LEIRKPGPFDGGIYTCKA 335
L C A P + W K+ ++ + H+ I + L+I++ D G YTC A
Sbjct: 2694 LECEAYAIPSASLSWYKDGQPLKSDD------HVNIAANGHTLQIKEAQISDTGRYTCVA 2747
Query: 336 VNPLGEASVDCRVDVKVP 353
N GE +D V+++VP
Sbjct: 2748 SNIAGEDELDFDVNIQVP 2765
Score = 33.5 bits (75), Expect = 0.30
Identities = 34/137 (24%), Positives = 54/137 (39%), Gaps = 11/137 (8%)
Query: 227 LSETAPITTDLAHIQKA--------ATVYKTKGFAQR--DFSEAPKFTQPLADCTTVTGY 276
L E+A + D+A + + A G AQ D SE P Q + T G
Sbjct: 476 LKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGE 535
Query: 277 NTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAV 336
L C + ++ + W +N D++ R T L SLE++ D G Y C
Sbjct: 536 RAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRT-LANLSLELKSVKFNDAGEYHCMVS 594
Query: 337 NPLGEASVDCRVDVKVP 353
+ G ++ + V+ P
Sbjct: 595 SEGGSSAASVFLTVQEP 611
Score = 33.5 bits (75), Expect = 0.30
Identities = 76/355 (21%), Positives = 121/355 (34%), Gaps = 48/355 (13%)
Query: 9 VAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVG 68
++ G L++ A D AG T + + + P I + Q+ + +
Sbjct: 3671 LSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPNI---KGGPQSLVILLN 3727
Query: 69 DTVNLLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQLR 126
+ L +G P P+ W DG L + R S+ ++ L I+ A D+GRY
Sbjct: 3728 KSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSIL---ENGFLHIQSAHVTDTGRYLCM 3784
Query: 127 VQLGGLEATATIDILV----IERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTV 182
ID+ V PGP +V+V A P+ + N G+ +
Sbjct: 3785 ATNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLL 3844
Query: 183 QKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQK 242
+ N ++R+ + L +P D A +
Sbjct: 3845 N--------------------------VDQNQNSYRLLSSG--SLVIISPSVDDTATYE- 3875
Query: 243 AATVYKTKGFAQRDFSEAPKFTQPLADCTT---VTGYNTQLFCCVRAS-PRPKIIWLKNK 298
TV G +R + +AD T VT + + C + P P I W KN
Sbjct: 3876 -CTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN- 3933
Query: 299 MDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVP 353
I+ P+ L ++EI G YTC A N G A + V P
Sbjct: 3934 -GIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEP 3987
Score = 32.0 bits (71), Expect = 0.86
Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 1/80 (1%)
Query: 44 LPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRN 103
+PPI +W P + KV +T+ L P W DG L + V
Sbjct: 2665 IPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDD-HVNI 2723
Query: 104 GEQDSILFIREAQRADSGRY 123
L I+EAQ +D+GRY
Sbjct: 2724 AANGHTLQIKEAQISDTGRY 2743
Score = 29.6 bits (65), Expect = 4.3
Identities = 22/77 (28%), Positives = 30/77 (38%), Gaps = 2/77 (2%)
Query: 277 NTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAV 336
+ L C P P I W K+ + + R L+ G L + + D G YTC
Sbjct: 2403 SVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILS--GGRMLRLMQTTMEDAGQYTCVVR 2460
Query: 337 NPLGEASVDCRVDVKVP 353
N GE + V VP
Sbjct: 2461 NAAGEERKIFGLSVLVP 2477
>gi|15147240 brother of CDO [Homo sapiens]
Length = 1114
Score = 56.2 bits (134), Expect = 4e-08
Identities = 41/149 (27%), Positives = 68/149 (45%), Gaps = 27/149 (18%)
Query: 199 YHRTSCIVSDLIIG-----NSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFA 253
Y++T ++S+L+I +S +R A+N G A I +Y + F
Sbjct: 274 YNKTRFLLSNLLIDTTSEEDSGTYRCMADNGVGQPGAAVI------------LYNVQVF- 320
Query: 254 QRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHL 313
E P+ T L+ G + +L C VR +P P ++WL+N + + + + R L
Sbjct: 321 -----EPPEVTMELSQLVIPWGQSAKLTCEVRGNPPPSVLWLRNAVPLISSQRLR----L 371
Query: 314 GICSLEIRKPGPFDGGIYTCKAVNPLGEA 342
+L + GP D G+Y C A N +G A
Sbjct: 372 SRRALRVLSMGPEDEGVYQCMAENEVGSA 400
Score = 43.1 bits (100), Expect = 4e-04
Identities = 57/272 (20%), Positives = 109/272 (40%), Gaps = 41/272 (15%)
Query: 91 GCALDTRRVSVR--------NGEQDSI--------LFIREAQRADSGRYQLRVQLGGLEA 134
GC ++ R++V NG D++ L I GRYQ ++ A
Sbjct: 56 GCVVEPPRMNVTWRLNGKELNGSDDALGVLITHGTLVITALNNHTVGRYQCVARMPA-GA 114
Query: 135 TATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFT 194
A++ P ++ L ++ F ++ D GNTA++ + ++ K+ + ++
Sbjct: 115 VASV----------PATVTLANLQDFKLDVQHVIEVDEGNTAVIACHLPESHPKAQVRYS 164
Query: 195 VLEHYHRTSCIVSDLII---GNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKG 251
V + + S + +I GN E++ G+ + A ++ + + + +
Sbjct: 165 VKQEWLEASR--GNYLIMPSGNLQIVNASQEDE-GMYKCAAYNPVTQEVKTSGSSDRLR- 220
Query: 252 FAQRDFSEAPKFTQPLADCTTVT--GYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRA 309
+R +EA + P T + G + L C P P++ W K+ + G K R
Sbjct: 221 -VRRSTAEAARIIYPPEAQTIIVTKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRF 279
Query: 310 LTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
L + +L I D G Y C A N +G+
Sbjct: 280 L----LSNLLIDTTSEEDSGTYRCMADNGVGQ 307
Score = 31.2 bits (69), Expect = 1.5
Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 15/119 (12%)
Query: 53 IWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCAL---DTRRVSVRNGEQDSI 109
I+ P A QT I G ++ L G P P+ W DG ++ + R + N
Sbjct: 232 IYPPEA--QTIIVTKGQSLILECVASGIPPPRVTWAKDGSSVTGYNKTRFLLSN------ 283
Query: 110 LFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSI----KLVDVWGFSATL 164
L I DSG Y+ G + A + + ++ PP+ +LV WG SA L
Sbjct: 284 LLIDTTSEEDSGTYRCMADNGVGQPGAAVILYNVQVFEPPEVTMELSQLVIPWGQSAKL 342
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 55.5 bits (132), Expect = 7e-08
Identities = 46/155 (29%), Positives = 71/155 (45%), Gaps = 13/155 (8%)
Query: 86 IWTHDGCALDTRRVSV---RNGEQDSI--LFIREAQRADSGRYQLRVQLGGLEATATIDI 140
+W+ +G +D + ++ RN DS L IR AQ +GRY Q ++A+ D+
Sbjct: 539 VWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSASADL 598
Query: 141 LVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWF------T 194
+V PGPP +++ D+ S L W+ D ++ + YT+Q S W
Sbjct: 599 VVRGPPGPPGGLRIEDIRATSVALTWSRGSD-NHSPISKYTIQTKTILSDDWKDAKTDPP 657
Query: 195 VLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229
++E + V DLI Y FRV A N G E
Sbjct: 658 IIEGNMEAARAV-DLIPWMEYEFRVVATNTLGRGE 691
Score = 34.3 bits (77), Expect = 0.17
Identities = 22/62 (35%), Positives = 30/62 (48%), Gaps = 3/62 (4%)
Query: 282 CCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGE 341
C +A+P+PK W K + + + SLEI DGGIYTC A N G+
Sbjct: 436 CKPKAAPKPKFSWSKGTEWLVNSSRILIWED---GSLEINNITRNDGGIYTCFAENNRGK 492
Query: 342 AS 343
A+
Sbjct: 493 AN 494
Score = 28.5 bits (62), Expect = 9.5
Identities = 24/83 (28%), Positives = 35/83 (42%), Gaps = 4/83 (4%)
Query: 269 DCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDG 328
D + G N L C +P P I W K ++ P ++ G L+I D
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRK---VLEPMPSTAEISTSG-AVLKIFNIQLEDE 305
Query: 329 GIYTCKAVNPLGEASVDCRVDVK 351
GIY C+A N G+ R+ V+
Sbjct: 306 GIYECEAENIRGKDKHQARIYVQ 328
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,823,775
Number of Sequences: 37866
Number of extensions: 799641
Number of successful extensions: 6848
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 146
Number of HSP's successfully gapped in prelim test: 154
Number of HSP's that attempted gapping in prelim test: 3678
Number of HSP's gapped (non-prelim): 2238
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.