BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo sapiens] (373 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 756 0.0 gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 756 0.0 gi|116268111 short chain dehydrogenase/reductase family 42E, mem... 174 2e-43 gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr... 145 4e-35 gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ... 145 4e-35 gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ... 145 4e-35 gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s... 125 5e-29 gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens] 113 2e-25 gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 105 9e-23 gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens] 71 2e-12 gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 65 8e-11 gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 65 8e-11 gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] 50 3e-06 gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] 45 8e-05 gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] 45 8e-05 gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] 45 8e-05 gi|33519455 methionine adenosyltransferase II, beta isoform 2 [H... 39 0.008 gi|11034825 methionine adenosyltransferase II, beta isoform 1 [H... 37 0.037 gi|169163903 PREDICTED: hypothetical protein [Homo sapiens] 32 0.71 gi|239747712 PREDICTED: hypothetical protein XP_002348233 [Homo ... 32 0.71 gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9... 32 0.71 gi|40068481 SET domain containing 3 isoform a [Homo sapiens] 32 1.2 gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] 30 3.5 gi|239741578 PREDICTED: hypothetical protein XP_002342256 [Homo ... 30 3.5 gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens] 30 3.5 gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] 30 3.5 gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 30 4.6 gi|115430219 lambda-crystallin [Homo sapiens] 30 4.6 gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] 29 6.0 gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] 29 6.0 >gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo sapiens] Length = 373 Score = 756 bits (1952), Expect = 0.0 Identities = 373/373 (100%), Positives = 373/373 (100%) Query: 1 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR Sbjct: 1 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60 Query: 61 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV Sbjct: 61 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120 Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE Sbjct: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180 Query: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV Sbjct: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240 Query: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA Sbjct: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300 Query: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME Sbjct: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360 Query: 361 RTVQSFRHLRRVK 373 RTVQSFRHLRRVK Sbjct: 361 RTVQSFRHLRRVK 373 >gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sapiens] Length = 373 Score = 756 bits (1952), Expect = 0.0 Identities = 373/373 (100%), Positives = 373/373 (100%) Query: 1 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR Sbjct: 1 MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60 Query: 61 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV Sbjct: 61 GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120 Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE Sbjct: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180 Query: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV Sbjct: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240 Query: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA Sbjct: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300 Query: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME Sbjct: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360 Query: 361 RTVQSFRHLRRVK 373 RTVQSFRHLRRVK Sbjct: 361 RTVQSFRHLRRVK 373 >gi|116268111 short chain dehydrogenase/reductase family 42E, member 1 [Homo sapiens] Length = 393 Score = 174 bits (440), Expect = 2e-43 Identities = 110/333 (33%), Positives = 172/333 (51%), Gaps = 16/333 (4%) Query: 34 QNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN-PQ-VRFFLGDLCSRQDL 91 ++Q + + GGSG+ G + L G V +FDI P+ ++F GD+ D+ Sbjct: 5 RSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDV 64 Query: 92 YPALKG--VNTVFHCASPPPSSN---NKELFYRVNYIGTKNVIETCKEAGVQKLILTSSA 146 A + V VFH AS S N+ L VN GT N+++ C+ V +L+ TS+ Sbjct: 65 EKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTF 124 Query: 147 SVIFEGVDIKNGTEDLPYAMKPI--DYYTETKILQERAVLGANDPEKN-----FLTTAIR 199 +VIF G I+NG E LPY + D+Y+ TK + E+ VL AN + T A+R Sbjct: 125 NVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALR 184 Query: 200 PHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDS- 258 P GI+GP + + +P ++ G KFV G+ ++LV+F V+N+V HILA+E L D Sbjct: 185 PAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKG 244 Query: 259 -TLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPV 317 G+ + I++ P+ + F ++ GL Y P +P + Y A L ++ ++ + Sbjct: 245 HIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRL 304 Query: 318 IQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQ 350 QP T V G HY+S E+AKK +GY+ Sbjct: 305 YNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337 >gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family protein ENSP00000330812 [Homo sapiens] Length = 422 Score = 145 bits (367), Expect = 4e-35 Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%) Query: 6 SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65 S P R + P+ K + ++ V GG G+LG + L G +V Sbjct: 3 SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61 Query: 66 VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120 + D + Q +P+ +F D+ + LY A +GV+ VFH AS S K E + Sbjct: 62 LLDRRRPQWELSPETKFIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121 Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177 N GTK VI+ C V +LI TS+ +V F G I+ G ED +PY + +D+Y+ TK Sbjct: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181 Query: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233 + ++ L AN P L T + RP GI+GP + + +P + + F G+ K Sbjct: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241 Query: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291 +++ V N+V H+LAAE L+ + G+A++I + E + + +++ + L Y P Sbjct: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301 Query: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351 +P Y A ++ L + + P+ L P T V H + +A+ +GY P Sbjct: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361 Query: 352 -LVTMDDAMERTVQS 365 DA+E VQS Sbjct: 362 DKFRFADAVELYVQS 376 >gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo sapiens] Length = 422 Score = 145 bits (367), Expect = 4e-35 Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%) Query: 6 SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65 S P R + P+ K + ++ V GG G+LG + L G +V Sbjct: 3 SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61 Query: 66 VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120 + D + Q +P+ +F D+ + LY A +GV+ VFH AS S K E + Sbjct: 62 LLDRRRPQWELSPETKFIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121 Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177 N GTK VI+ C V +LI TS+ +V F G I+ G ED +PY + +D+Y+ TK Sbjct: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181 Query: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233 + ++ L AN P L T + RP GI+GP + + +P + + F G+ K Sbjct: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241 Query: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291 +++ V N+V H+LAAE L+ + G+A++I + E + + +++ + L Y P Sbjct: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301 Query: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351 +P Y A ++ L + + P+ L P T V H + +A+ +GY P Sbjct: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361 Query: 352 -LVTMDDAMERTVQS 365 DA+E VQS Sbjct: 362 DKFRFADAVELYVQS 376 >gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo sapiens] Length = 422 Score = 145 bits (367), Expect = 4e-35 Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%) Query: 6 SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65 S P R + P+ K + ++ V GG G+LG + L G +V Sbjct: 3 SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61 Query: 66 VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120 + D + Q +P+ +F D+ + LY A +GV+ VFH AS S K E + Sbjct: 62 LLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121 Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177 N GTK VI+ C V +LI TS+ +V F G I+ G ED +PY + +D+Y+ TK Sbjct: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181 Query: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233 + ++ L AN P L T + RP GI+GP + + +P + + F G+ K Sbjct: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241 Query: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291 +++ V N+V H+LAAE L+ + G+A++I + E + + +++ + L Y P Sbjct: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301 Query: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351 +P Y A ++ L + + P+ L P T V H + +A+ +GY P Sbjct: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361 Query: 352 -LVTMDDAMERTVQS 365 DA+E VQS Sbjct: 362 DKFRFADAVELYVQS 376 >gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 isoform a [Homo sapiens] Length = 369 Score = 125 bits (315), Expect = 5e-29 Identities = 103/345 (29%), Positives = 157/345 (45%), Gaps = 23/345 (6%) Query: 42 VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91 V GG GFLG+H+V LL R + VFD G +V GD+ ++ Sbjct: 14 VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73 Query: 92 YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149 A+ G + V H A + + + VN GT+NVIE C + G + L+ TSS V+ Sbjct: 74 AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133 Query: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKN----FLTTAIRPHG 202 +G G ED PY Y +K L E VL AN + +T A+RP G Sbjct: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTG 193 Query: 203 IFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTL-G 261 I+G + + R G F +V NV H+LAA +L + +TL G Sbjct: 194 IYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELEQRATLMG 253 Query: 262 GKAFHITNDEPI-PFWTFLSRIL--TGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVI 318 G+ + + P + F L GL + +PYW+ +LA L +LL ++ P++ Sbjct: 254 GQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQWLLRPLV 313 Query: 319 QLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTV 363 P P +A+A T S ++A++ GY+PL + +D+ RT+ Sbjct: 314 LYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTI 358 >gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens] Length = 372 Score = 113 bits (283), Expect = 2e-25 Identities = 99/354 (27%), Positives = 168/354 (47%), Gaps = 33/354 (9%) Query: 40 CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86 C V G G LGQ +V L+ + + + F P++R GD+ Sbjct: 5 CLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAF-RPELREEFSKLQNRTKLTVLEGDIL 63 Query: 87 SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144 L A + V+ V H C ++E VN GT+ ++E C +A V I TS Sbjct: 64 DEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 123 Query: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196 S V ++ + I+NG E+ P Y +K L E+AVL AN KN T Sbjct: 124 SIEVAGPNSYKEI-IQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTC 182 Query: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQL-- 254 A+RP I+G P L + EA N + +G V+ +V NV HILA L Sbjct: 183 ALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALRD 241 Query: 255 -SRDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310 + ++ G+ ++I++D P + L+ IL+ GL ++ ++ +P + Y++ LL ++ Sbjct: 242 PKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDS-RWSLPLTLMYWIGFLLEVV 300 Query: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364 ++SP+ QP F V L+ + +S ++A++ + Y+PL + ++A ++TV+ Sbjct: 301 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 354 >gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] Length = 373 Score = 105 bits (261), Expect = 9e-23 Identities = 94/354 (26%), Positives = 165/354 (46%), Gaps = 33/354 (9%) Query: 40 CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86 C V G GFLGQ ++ L+ + + + F P++R GD+ Sbjct: 6 CLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAF-GPELREEFSKLQNKTKLTVLEGDIL 64 Query: 87 SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144 L A + V+ + H C ++E VN GT+ ++E C +A V I TS Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124 Query: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196 S V ++ + I+NG E+ P Y +K L E+AVL AN KN T Sbjct: 125 SIEVAGPNSYKEI-IQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTC 183 Query: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLS- 255 A+RP I+G L + EA N + +G V+ +V NV HILA L Sbjct: 184 ALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALQD 242 Query: 256 --RDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310 + ++ G+ ++I++D P + L+ L+ GL ++ ++ P + Y++ LL ++ Sbjct: 243 PKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDS-RWSFPLSLMYWIGFLLEIV 301 Query: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364 ++ P+ +P F V L+ + +S ++A++ + Y+PL + ++A ++TV+ Sbjct: 302 SFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 355 >gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens] Length = 420 Score = 70.9 bits (172), Expect = 2e-12 Identities = 69/275 (25%), Positives = 122/275 (44%), Gaps = 20/275 (7%) Query: 7 EPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNV 66 EP+R+++ L + + ++ +++ KR + GG+GF+G H+ ++L+ G+ V V Sbjct: 60 EPLREKIR--DLEKSFTQKYPPVKFLSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTV 117 Query: 67 FDIQQGFDNPQVRFFLG----DLCSRQDLYPALKGVNTVFHCASPPPSSN---NKELFYR 119 D V ++G +L + + P V+ ++H ASP N N + Sbjct: 118 VDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLK 177 Query: 120 VNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPID---YYTETK 176 N IGT N++ K G + +L +S S ++ ++ +ED + PI Y E K Sbjct: 178 TNTIGTLNMLGLAKRVGAR--LLLASTSEVYGDPEVHPQSEDYWGHVNPIGPRACYDEGK 235 Query: 177 ILQERAVLGANDPEKNFLTTAIRPHGIFGPR----DPQLVPILIEAARNGKMKFVIGNGK 232 + E + A ++ R FGPR D ++V I A G+ V G+G Sbjct: 236 RVAE-TMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGS 294 Query: 233 NLVDFTFVENVVHGHI-LAAEQLSRDSTLGGKAFH 266 F +V ++V+G + L +S LG H Sbjct: 295 QTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEH 329 >gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 isoform b [Homo sapiens] Length = 196 Score = 65.5 bits (158), Expect = 8e-11 Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 15/161 (9%) Query: 42 VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91 V GG GFLG+H+V LL R + VFD G +V GD+ ++ Sbjct: 14 VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73 Query: 92 YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149 A+ G + V H A + + + VN GT+NVIE C + G + L+ TSS V+ Sbjct: 74 AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133 Query: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187 +G G ED PY Y +K L E VL AN Sbjct: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEAN 174 >gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 isoform b [Homo sapiens] Length = 196 Score = 65.5 bits (158), Expect = 8e-11 Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 15/161 (9%) Query: 42 VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91 V GG GFLG+H+V LL R + VFD G +V GD+ ++ Sbjct: 14 VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73 Query: 92 YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149 A+ G + V H A + + + VN GT+NVIE C + G + L+ TSS V+ Sbjct: 74 AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133 Query: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187 +G G ED PY Y +K L E VL AN Sbjct: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEAN 174 >gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] Length = 350 Score = 50.4 bits (119), Expect = 3e-06 Identities = 54/231 (23%), Positives = 93/231 (40%), Gaps = 23/231 (9%) Query: 37 AKRCTVIGGSGFLGQHMVEQLL------------ARGYAVNVFDIQQGFDNPQVRFFLGD 84 AKR V GG+GF+ HM+ L+ Y ++ +++ + +F GD Sbjct: 17 AKRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGD 76 Query: 85 LCSRQ--DLYPALKGVNTVFHCASPPP---SSNNKELFYRVNYIGTKNVIETCKEAGVQK 139 +C L + ++ V H A+ S F VN GT ++ EA V+K Sbjct: 77 ICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEK 136 Query: 140 LILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIR 199 I S+ V +D K E P +P + Y +K E V + K F R Sbjct: 137 FIYVSTDEVYGGSLD-KEFDESSP--KQPTNPYASSKAAAECFVQSYWEQYK-FPVVITR 192 Query: 200 PHGIFGPRD--PQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHI 248 ++GP +++P I ++ + + G+G +F + +VV + Sbjct: 193 SSNVYGPHQYPEKVIPKFISLLQHNRKCCIHGSGLQTRNFLYATDVVEAFL 243 >gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] Length = 348 Score = 45.4 bits (106), Expect = 8e-05 Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%) Query: 37 AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79 A++ V GG+G++G H V +LL GY V D + G P+ V Sbjct: 2 AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61 Query: 80 FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134 F D+ + L K + V H A S K L +YRVN GT ++E K Sbjct: 62 FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121 Query: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190 GV+ L+ +SSA+V + +D + T + Y ++K E + + Sbjct: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175 Query: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236 K F T G G DPQ L+P + + A + V GN + D Sbjct: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234 Query: 237 FTFVENVVH------GHILAAEQL 254 T V + +H GHI A +L Sbjct: 235 GTGVRDYIHVVDLAKGHIAALRKL 258 >gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] Length = 348 Score = 45.4 bits (106), Expect = 8e-05 Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%) Query: 37 AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79 A++ V GG+G++G H V +LL GY V D + G P+ V Sbjct: 2 AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61 Query: 80 FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134 F D+ + L K + V H A S K L +YRVN GT ++E K Sbjct: 62 FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121 Query: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190 GV+ L+ +SSA+V + +D + T + Y ++K E + + Sbjct: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175 Query: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236 K F T G G DPQ L+P + + A + V GN + D Sbjct: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234 Query: 237 FTFVENVVH------GHILAAEQL 254 T V + +H GHI A +L Sbjct: 235 GTGVRDYIHVVDLAKGHIAALRKL 258 >gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] Length = 348 Score = 45.4 bits (106), Expect = 8e-05 Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%) Query: 37 AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79 A++ V GG+G++G H V +LL GY V D + G P+ V Sbjct: 2 AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61 Query: 80 FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134 F D+ + L K + V H A S K L +YRVN GT ++E K Sbjct: 62 FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121 Query: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190 GV+ L+ +SSA+V + +D + T + Y ++K E + + Sbjct: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175 Query: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236 K F T G G DPQ L+P + + A + V GN + D Sbjct: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234 Query: 237 FTFVENVVH------GHILAAEQL 254 T V + +H GHI A +L Sbjct: 235 GTGVRDYIHVVDLAKGHIAALRKL 258 >gi|33519455 methionine adenosyltransferase II, beta isoform 2 [Homo sapiens] Length = 323 Score = 38.9 bits (89), Expect = 0.008 Identities = 38/171 (22%), Positives = 78/171 (45%), Gaps = 15/171 (8%) Query: 23 PKVNADIEKVNQN-QAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFF 81 P++ D+E+ N +R V G +G LG+ + ++ + + GF + +F Sbjct: 2 PEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFE 57 Query: 82 LGDLCSRQDLYPALKGV--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAG 136 +L ++ + + + HCA+ P N + ++N + N+ + + A Sbjct: 58 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAA 115 Query: 137 VQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187 V ++ S+ +F+G + ED+P P++ Y +TK+ E+AVL N Sbjct: 116 VGAFLIYISSDYVFDGTNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 163 >gi|11034825 methionine adenosyltransferase II, beta isoform 1 [Homo sapiens] Length = 334 Score = 36.6 bits (83), Expect = 0.037 Identities = 34/155 (21%), Positives = 70/155 (45%), Gaps = 14/155 (9%) Query: 38 KRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKG 97 +R V G +G LG+ + ++ + + GF + +F +L ++ + Sbjct: 29 RRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFEQVNLLDSNAVHHIIHD 84 Query: 98 V--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEG 152 + + HCA+ P N + ++N + N+ + + A V ++ S+ +F+G Sbjct: 85 FQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVFDG 142 Query: 153 VDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187 + ED+P P++ Y +TK+ E+AVL N Sbjct: 143 TNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 174 >gi|169163903 PREDICTED: hypothetical protein [Homo sapiens] Length = 113 Score = 32.3 bits (72), Expect = 0.71 Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 25/111 (22%) Query: 17 HLTEDTPK-VNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN 75 HL +D PK D+E V Q GF G H V ++ + + V F Sbjct: 21 HLLDDQPKGEGGDVEHVQQR-----------GFAGSHFVSMVIPKAWKKEV------FSG 63 Query: 76 PQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTK 126 P+ F+ G + S + PA T+ +SN + R + + TK Sbjct: 64 PRPVFWAGTVTSHGAMAPARAAAGTLL-------ASNMSLISVRSSLVNTK 107 >gi|239747712 PREDICTED: hypothetical protein XP_002348233 [Homo sapiens] Length = 113 Score = 32.3 bits (72), Expect = 0.71 Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 25/111 (22%) Query: 17 HLTEDTPK-VNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN 75 HL +D PK D+E V Q GF G H V ++ + + V F Sbjct: 21 HLLDDQPKGEGGDVEHVQQR-----------GFAGSHFVSMVIPKAWKKEV------FSG 63 Query: 76 PQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTK 126 P+ F+ G + S + PA T+ +SN + R + + TK Sbjct: 64 PRPVFWAGTVTSHGAMAPARAAAGTLL-------ASNMSLISVRSSLVNTK 107 >gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa [Homo sapiens] Length = 377 Score = 32.3 bits (72), Expect = 0.71 Identities = 52/237 (21%), Positives = 94/237 (39%), Gaps = 42/237 (17%) Query: 41 TVIGGSGFLGQHMVEQLLARGYAV---------NVFDIQQGFDNPQVRFFLGDLCSRQDL 91 TV G +GFLG+++V L G V ++ ++ D Q+ F D + + Sbjct: 57 TVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMHLRPMGDLGQLLFLEWDARDKDSI 116 Query: 92 YPALKGVNTVFHCASPPPSSNN---KELFYRVNYIGTKNVIETCKEAGVQKLILTSSASV 148 ++ N V + + N +++F ++ + + + KEAGV+K I S + Sbjct: 117 RRVVQHSNVVINLIGRDWETKNFDFEDVFVKI----PQAIAQLSKEAGVEKFIHVSHLN- 171 Query: 149 IFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRD 208 +IK+ + Y K + E+ V A PE ++P IFG R+ Sbjct: 172 ----ANIKSSSR-----------YLRNKAVGEKVVRDA-FPE----AIIVKPSDIFG-RE 210 Query: 209 PQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTLGGKAF 265 + + R G + K + +V +V G + A +D GK+F Sbjct: 211 DRFLNSFASMHRFGPIPLGSLGWKTVKQPVYVVDVSKGIVNAV----KDPDANGKSF 263 >gi|40068481 SET domain containing 3 isoform a [Homo sapiens] Length = 594 Score = 31.6 bits (70), Expect = 1.2 Identities = 14/43 (32%), Positives = 20/43 (46%) Query: 237 FTFVENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFL 279 F E + H+L + R TLG F ++ D + WTFL Sbjct: 388 FCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFL 430 >gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] Length = 323 Score = 30.0 bits (66), Expect = 3.5 Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145 P N K LF V+ T +E CK+AG+ K I S+ Sbjct: 130 PKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSN 167 >gi|239741578 PREDICTED: hypothetical protein XP_002342256 [Homo sapiens] Length = 113 Score = 30.0 bits (66), Expect = 3.5 Identities = 27/111 (24%), Positives = 43/111 (38%), Gaps = 25/111 (22%) Query: 17 HLTEDTPK-VNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN 75 +L +D PK D+E V Q GF G H V ++ + + V F Sbjct: 21 YLLDDQPKGEGGDVEHVQQR-----------GFAGSHFVSMVIPKAWKKEV------FSG 63 Query: 76 PQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTK 126 P+ F+ G + S + PA T+ +SN + R + + TK Sbjct: 64 PRPVFWAGTVTSHGAMAPARAAAGTLL-------ASNMSLISVRSSLVNTK 107 >gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens] Length = 326 Score = 30.0 bits (66), Expect = 3.5 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 3/75 (4%) Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSAS-VIFEGVDIKNGTEDLPYA- 165 P N K L+++ N T +E CK+AG+ K + S+ + E + K G + P + Sbjct: 133 PRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSN 192 Query: 166 -MKPIDYYTETKILQ 179 ++ Y+T+ K+L+ Sbjct: 193 QVECHPYFTQPKLLK 207 >gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] Length = 323 Score = 30.0 bits (66), Expect = 3.5 Identities = 15/38 (39%), Positives = 21/38 (55%) Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145 P N K +F V+ T V+E CK+AG+ K I S+ Sbjct: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSN 167 >gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] Length = 1039 Score = 29.6 bits (65), Expect = 4.6 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 7/86 (8%) Query: 14 ARTHLTEDTP-KVNADIEKVNQNQAKRCTVIGGS-GFLGQHMVEQLLARGYAVNVFDIQQ 71 A + ED ++N +E+VN+ AK V G + ++++LA N +I Sbjct: 651 ANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILA-----NYQEIVF 705 Query: 72 GFDNPQVRFFLGDLCSRQDLYPALKG 97 +PQ + + + C RQD A+ G Sbjct: 706 ARTSPQQKLIIVEGCQRQDAVVAVTG 731 >gi|115430219 lambda-crystallin [Homo sapiens] Length = 319 Score = 29.6 bits (65), Expect = 4.6 Identities = 13/37 (35%), Positives = 21/37 (56%) Query: 35 NQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQ 71 + A C VI GSG +G+ + G+ V ++DI+Q Sbjct: 3 SSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQ 39 >gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] Length = 323 Score = 29.3 bits (64), Expect = 6.0 Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145 P N K LF V+ T +E CK+AG+ K I S+ Sbjct: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167 >gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] Length = 323 Score = 29.3 bits (64), Expect = 6.0 Identities = 15/38 (39%), Positives = 20/38 (52%) Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145 P N K LF V+ T +E CK+AG+ K I S+ Sbjct: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.138 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,000,212 Number of Sequences: 37866 Number of extensions: 600689 Number of successful extensions: 1233 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 22 Number of HSP's successfully gapped in prelim test: 11 Number of HSP's that attempted gapping in prelim test: 1178 Number of HSP's gapped (non-prelim): 37 length of query: 373 length of database: 18,247,518 effective HSP length: 104 effective length of query: 269 effective length of database: 14,309,454 effective search space: 3849243126 effective search space used: 3849243126 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.