Guide to the Human Genome
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Search of human proteins with 193211614

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
         (373 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s...   756   0.0  
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap...   756   0.0  
gi|116268111 short chain dehydrogenase/reductase family 42E, mem...   174   2e-43
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr...   145   4e-35
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ...   145   4e-35
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ...   145   4e-35
gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...   125   5e-29
gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]       113   2e-25
gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]       105   9e-23
gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]             71   2e-12
gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...    65   8e-11
gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...    65   8e-11
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]                  50   3e-06
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]                   45   8e-05
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]                   45   8e-05
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]                  45   8e-05
gi|33519455 methionine adenosyltransferase II, beta isoform 2 [H...    39   0.008
gi|11034825 methionine adenosyltransferase II, beta isoform 1 [H...    37   0.037
gi|169163903 PREDICTED: hypothetical protein [Homo sapiens]            32   0.71 
gi|239747712 PREDICTED: hypothetical protein XP_002348233 [Homo ...    32   0.71 
gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9...    32   0.71 
gi|40068481 SET domain containing 3 isoform a [Homo sapiens]           32   1.2  
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]      30   3.5  
gi|239741578 PREDICTED: hypothetical protein XP_002342256 [Homo ...    30   3.5  
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]      30   3.5  
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]     30   3.5  
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]    30   4.6  
gi|115430219 lambda-crystallin [Homo sapiens]                          30   4.6  
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]     29   6.0  
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]      29   6.0  

>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score =  756 bits (1952), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60
           MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
Sbjct: 1   MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60

Query: 61  GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120
           GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
Sbjct: 61  GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120

Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180
           NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
Sbjct: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180

Query: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240
           RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
Sbjct: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240

Query: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300
           ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
Sbjct: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300

Query: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360
           YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
Sbjct: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360

Query: 361 RTVQSFRHLRRVK 373
           RTVQSFRHLRRVK
Sbjct: 361 RTVQSFRHLRRVK 373


>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score =  756 bits (1952), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60
           MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR
Sbjct: 1   MEPAVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR 60

Query: 61  GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120
           GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV
Sbjct: 61  GYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRV 120

Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180
           NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE
Sbjct: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQE 180

Query: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240
           RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV
Sbjct: 181 RAVLGANDPEKNFLTTAIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFV 240

Query: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300
           ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA
Sbjct: 241 ENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVA 300

Query: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360
           YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME
Sbjct: 301 YYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAME 360

Query: 361 RTVQSFRHLRRVK 373
           RTVQSFRHLRRVK
Sbjct: 361 RTVQSFRHLRRVK 373


>gi|116268111 short chain dehydrogenase/reductase family 42E, member
           1 [Homo sapiens]
          Length = 393

 Score =  174 bits (440), Expect = 2e-43
 Identities = 110/333 (33%), Positives = 172/333 (51%), Gaps = 16/333 (4%)

Query: 34  QNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN-PQ-VRFFLGDLCSRQDL 91
           ++Q +   + GGSG+ G  +   L   G  V +FDI       P+ ++F  GD+    D+
Sbjct: 5   RSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDV 64

Query: 92  YPALKG--VNTVFHCASPPPSSN---NKELFYRVNYIGTKNVIETCKEAGVQKLILTSSA 146
             A +   V  VFH AS   S     N+ L   VN  GT N+++ C+   V +L+ TS+ 
Sbjct: 65  EKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTF 124

Query: 147 SVIFEGVDIKNGTEDLPYAMKPI--DYYTETKILQERAVLGANDPEKN-----FLTTAIR 199
           +VIF G  I+NG E LPY    +  D+Y+ TK + E+ VL AN    +       T A+R
Sbjct: 125 NVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALR 184

Query: 200 PHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDS- 258
           P GI+GP + + +P ++     G  KFV G+ ++LV+F  V+N+V  HILA+E L  D  
Sbjct: 185 PAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKG 244

Query: 259 -TLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPV 317
               G+ + I++  P+  + F   ++ GL Y  P   +P  + Y  A L  ++  ++  +
Sbjct: 245 HIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRL 304

Query: 318 IQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQ 350
              QP  T   V   G  HY+S E+AKK +GY+
Sbjct: 305 YNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337


>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
           protein ENSP00000330812 [Homo sapiens]
          Length = 422

 Score =  145 bits (367), Expect = 4e-35
 Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%)

Query: 6   SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65
           S P R  +         P+      K  +   ++  V GG G+LG  +   L   G +V 
Sbjct: 3   SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61

Query: 66  VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120
           + D +  Q   +P+ +F   D+   + LY A +GV+ VFH AS   S   K   E    +
Sbjct: 62  LLDRRRPQWELSPETKFIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121

Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177
           N  GTK VI+ C    V +LI TS+ +V F G  I+ G ED +PY    + +D+Y+ TK 
Sbjct: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181

Query: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233
           + ++  L AN    P    L T + RP GI+GP + + +P +    +     F  G+ K 
Sbjct: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241

Query: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291
            +++  V N+V  H+LAAE L+  +     G+A++I + E +  + +++ +   L Y  P
Sbjct: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301

Query: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351
              +P    Y  A ++  L + + P+  L P  T   V      H +   +A+  +GY P
Sbjct: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361

Query: 352 -LVTMDDAMERTVQS 365
                 DA+E  VQS
Sbjct: 362 DKFRFADAVELYVQS 376


>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
           sapiens]
          Length = 422

 Score =  145 bits (367), Expect = 4e-35
 Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%)

Query: 6   SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65
           S P R  +         P+      K  +   ++  V GG G+LG  +   L   G +V 
Sbjct: 3   SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61

Query: 66  VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120
           + D +  Q   +P+ +F   D+   + LY A +GV+ VFH AS   S   K   E    +
Sbjct: 62  LLDRRRPQWELSPETKFIQADVRDEEALYHAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121

Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177
           N  GTK VI+ C    V +LI TS+ +V F G  I+ G ED +PY    + +D+Y+ TK 
Sbjct: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181

Query: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233
           + ++  L AN    P    L T + RP GI+GP + + +P +    +     F  G+ K 
Sbjct: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241

Query: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291
            +++  V N+V  H+LAAE L+  +     G+A++I + E +  + +++ +   L Y  P
Sbjct: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301

Query: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351
              +P    Y  A ++  L + + P+  L P  T   V      H +   +A+  +GY P
Sbjct: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361

Query: 352 -LVTMDDAMERTVQS 365
                 DA+E  VQS
Sbjct: 362 DKFRFADAVELYVQS 376


>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
           sapiens]
          Length = 422

 Score =  145 bits (367), Expect = 4e-35
 Identities = 109/375 (29%), Positives = 176/375 (46%), Gaps = 16/375 (4%)

Query: 6   SEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVN 65
           S P R  +         P+      K  +   ++  V GG G+LG  +   L   G +V 
Sbjct: 3   SNPPRSSLEACKAAGQAPQQKTQA-KPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVI 61

Query: 66  VFDIQ--QGFDNPQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNK---ELFYRV 120
           + D +  Q   +P+ +F   D+   + LY A +GV+ VFH AS   S   K   E    +
Sbjct: 62  LLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESI 121

Query: 121 NYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTED-LPYAM--KPIDYYTETKI 177
           N  GTK VI+ C    V +LI TS+ +V F G  I+ G ED +PY    + +D+Y+ TK 
Sbjct: 122 NVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKA 181

Query: 178 LQERAVLGAND---PEKNFLTTAI-RPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKN 233
           + ++  L AN    P    L T + RP GI+GP + + +P +    +     F  G+ K 
Sbjct: 182 IADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKA 241

Query: 234 LVDFTFVENVVHGHILAAEQLS--RDSTLGGKAFHITNDEPIPFWTFLSRILTGLNYEAP 291
            +++  V N+V  H+LAAE L+  +     G+A++I + E +  + +++ +   L Y  P
Sbjct: 242 RMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQP 301

Query: 292 KYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQP 351
              +P    Y  A ++  L + + P+  L P  T   V      H +   +A+  +GY P
Sbjct: 302 WIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361

Query: 352 -LVTMDDAMERTVQS 365
                 DA+E  VQS
Sbjct: 362 DKFRFADAVELYVQS 376


>gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform a [Homo sapiens]
          Length = 369

 Score =  125 bits (315), Expect = 5e-29
 Identities = 103/345 (29%), Positives = 157/345 (45%), Gaps = 23/345 (6%)

Query: 42  VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91
           V GG GFLG+H+V  LL R   +    VFD   G           +V    GD+    ++
Sbjct: 14  VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73

Query: 92  YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149
             A+ G + V H A         + +  + VN  GT+NVIE C + G + L+ TSS  V+
Sbjct: 74  AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133

Query: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKN----FLTTAIRPHG 202
               +G     G ED PY       Y  +K L E  VL AN  +       +T A+RP G
Sbjct: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTG 193

Query: 203 IFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTL-G 261
           I+G     +     +  R G   F            +V NV   H+LAA +L + +TL G
Sbjct: 194 IYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELEQRATLMG 253

Query: 262 GKAFHITNDEPI-PFWTFLSRIL--TGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVI 318
           G+ +   +  P   +  F    L   GL     +  +PYW+  +LA L +LL  ++ P++
Sbjct: 254 GQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQWLLRPLV 313

Query: 319 QLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTV 363
              P   P  +A+A T    S ++A++  GY+PL + +D+  RT+
Sbjct: 314 LYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTI 358


>gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
          Length = 372

 Score =  113 bits (283), Expect = 2e-25
 Identities = 99/354 (27%), Positives = 168/354 (47%), Gaps = 33/354 (9%)

Query: 40  CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86
           C V G  G LGQ +V  L+       +  + + F  P++R                GD+ 
Sbjct: 5   CLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAF-RPELREEFSKLQNRTKLTVLEGDIL 63

Query: 87  SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144
               L  A + V+ V H  C        ++E    VN  GT+ ++E C +A V   I TS
Sbjct: 64  DEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 123

Query: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196
           S  V     ++ + I+NG E+ P        Y  +K L E+AVL AN    KN     T 
Sbjct: 124 SIEVAGPNSYKEI-IQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTC 182

Query: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQL-- 254
           A+RP  I+G   P L   + EA  N  +   +G     V+  +V NV   HILA   L  
Sbjct: 183 ALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALRD 241

Query: 255 -SRDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310
             +  ++ G+ ++I++D P   +  L+ IL+   GL  ++ ++ +P  + Y++  LL ++
Sbjct: 242 PKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDS-RWSLPLTLMYWIGFLLEVV 300

Query: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364
             ++SP+   QP F    V L+ +   +S ++A++ + Y+PL + ++A ++TV+
Sbjct: 301 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 354


>gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 373

 Score =  105 bits (261), Expect = 9e-23
 Identities = 94/354 (26%), Positives = 165/354 (46%), Gaps = 33/354 (9%)

Query: 40  CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86
           C V G  GFLGQ ++  L+       +  + + F  P++R                GD+ 
Sbjct: 6   CLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAF-GPELREEFSKLQNKTKLTVLEGDIL 64

Query: 87  SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144
               L  A + V+ + H  C        ++E    VN  GT+ ++E C +A V   I TS
Sbjct: 65  DEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 124

Query: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196
           S  V     ++ + I+NG E+ P        Y  +K L E+AVL AN    KN     T 
Sbjct: 125 SIEVAGPNSYKEI-IQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYTC 183

Query: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLS- 255
           A+RP  I+G     L   + EA  N  +   +G     V+  +V NV   HILA   L  
Sbjct: 184 ALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALQD 242

Query: 256 --RDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310
             +  ++ G+ ++I++D P   +  L+  L+   GL  ++ ++  P  + Y++  LL ++
Sbjct: 243 PKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDS-RWSFPLSLMYWIGFLLEIV 301

Query: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364
             ++ P+   +P F    V L+ +   +S ++A++ + Y+PL + ++A ++TV+
Sbjct: 302 SFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 355


>gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]
          Length = 420

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 69/275 (25%), Positives = 122/275 (44%), Gaps = 20/275 (7%)

Query: 7   EPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNV 66
           EP+R+++    L +   +    ++ +++   KR  + GG+GF+G H+ ++L+  G+ V V
Sbjct: 60  EPLREKIR--DLEKSFTQKYPPVKFLSEKDRKRILITGGAGFVGSHLTDKLMMDGHEVTV 117

Query: 67  FDIQQGFDNPQVRFFLG----DLCSRQDLYPALKGVNTVFHCASPPPSSN---NKELFYR 119
            D         V  ++G    +L +   + P    V+ ++H ASP    N   N     +
Sbjct: 118 VDNFFTGRKRNVEHWIGHENFELINHDVVEPLYIEVDQIYHLASPASPPNYMYNPIKTLK 177

Query: 120 VNYIGTKNVIETCKEAGVQKLILTSSASVIFEGVDIKNGTEDLPYAMKPID---YYTETK 176
            N IGT N++   K  G +  +L +S S ++   ++   +ED    + PI     Y E K
Sbjct: 178 TNTIGTLNMLGLAKRVGAR--LLLASTSEVYGDPEVHPQSEDYWGHVNPIGPRACYDEGK 235

Query: 177 ILQERAVLGANDPEKNFLTTAIRPHGIFGPR----DPQLVPILIEAARNGKMKFVIGNGK 232
            + E  +  A   ++       R    FGPR    D ++V   I  A  G+   V G+G 
Sbjct: 236 RVAE-TMCYAYMKQEGVEVRVARIFNTFGPRMHMNDGRVVSNFILQALQGEPLTVYGSGS 294

Query: 233 NLVDFTFVENVVHGHI-LAAEQLSRDSTLGGKAFH 266
               F +V ++V+G + L    +S    LG    H
Sbjct: 295 QTRAFQYVSDLVNGLVALMNSNVSSPVNLGNPEEH 329


>gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform b [Homo sapiens]
          Length = 196

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 15/161 (9%)

Query: 42  VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91
           V GG GFLG+H+V  LL R   +    VFD   G           +V    GD+    ++
Sbjct: 14  VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73

Query: 92  YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149
             A+ G + V H A         + +  + VN  GT+NVIE C + G + L+ TSS  V+
Sbjct: 74  AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133

Query: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
               +G     G ED PY       Y  +K L E  VL AN
Sbjct: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEAN 174


>gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform b [Homo sapiens]
          Length = 196

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 15/161 (9%)

Query: 42  VIGGSGFLGQHMVEQLLARGYAVN---VFDIQQG-------FDNPQVRFFLGDLCSRQDL 91
           V GG GFLG+H+V  LL R   +    VFD   G           +V    GD+    ++
Sbjct: 14  VTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEV 73

Query: 92  YPALKGVNTVFHCASPPP--SSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI 149
             A+ G + V H A         + +  + VN  GT+NVIE C + G + L+ TSS  V+
Sbjct: 74  AAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVV 133

Query: 150 ---FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
               +G     G ED PY       Y  +K L E  VL AN
Sbjct: 134 GPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEAN 174


>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
          Length = 350

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 54/231 (23%), Positives = 93/231 (40%), Gaps = 23/231 (9%)

Query: 37  AKRCTVIGGSGFLGQHMVEQLL------------ARGYAVNVFDIQQGFDNPQVRFFLGD 84
           AKR  V GG+GF+  HM+  L+               Y  ++ +++   +    +F  GD
Sbjct: 17  AKRVLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGD 76

Query: 85  LCSRQ--DLYPALKGVNTVFHCASPPP---SSNNKELFYRVNYIGTKNVIETCKEAGVQK 139
           +C      L    + ++ V H A+      S      F  VN  GT  ++    EA V+K
Sbjct: 77  ICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEK 136

Query: 140 LILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIR 199
            I  S+  V    +D K   E  P   +P + Y  +K   E  V    +  K F     R
Sbjct: 137 FIYVSTDEVYGGSLD-KEFDESSP--KQPTNPYASSKAAAECFVQSYWEQYK-FPVVITR 192

Query: 200 PHGIFGPRD--PQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHI 248
              ++GP     +++P  I   ++ +   + G+G    +F +  +VV   +
Sbjct: 193 SSNVYGPHQYPEKVIPKFISLLQHNRKCCIHGSGLQTRNFLYATDVVEAFL 243


>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)

Query: 37  AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79
           A++  V GG+G++G H V +LL  GY   V D      + G   P+            V 
Sbjct: 2   AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61

Query: 80  FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134
           F   D+  +  L    K  +   V H A       S  K L +YRVN  GT  ++E  K 
Sbjct: 62  FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121

Query: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190
            GV+ L+ +SSA+V     +  +D  + T          + Y ++K   E  +      +
Sbjct: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175

Query: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236
           K         F  T     G  G  DPQ     L+P + + A   +    V GN  +  D
Sbjct: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234

Query: 237 FTFVENVVH------GHILAAEQL 254
            T V + +H      GHI A  +L
Sbjct: 235 GTGVRDYIHVVDLAKGHIAALRKL 258


>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)

Query: 37  AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79
           A++  V GG+G++G H V +LL  GY   V D      + G   P+            V 
Sbjct: 2   AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61

Query: 80  FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134
           F   D+  +  L    K  +   V H A       S  K L +YRVN  GT  ++E  K 
Sbjct: 62  FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121

Query: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190
            GV+ L+ +SSA+V     +  +D  + T          + Y ++K   E  +      +
Sbjct: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175

Query: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236
           K         F  T     G  G  DPQ     L+P + + A   +    V GN  +  D
Sbjct: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234

Query: 237 FTFVENVVH------GHILAAEQL 254
            T V + +H      GHI A  +L
Sbjct: 235 GTGVRDYIHVVDLAKGHIAALRKL 258


>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 70/264 (26%), Positives = 104/264 (39%), Gaps = 53/264 (20%)

Query: 37  AKRCTVIGGSGFLGQHMVEQLLARGYAVNVFD-----IQQGFDNPQ------------VR 79
           A++  V GG+G++G H V +LL  GY   V D      + G   P+            V 
Sbjct: 2   AEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVE 61

Query: 80  FFLGDLCSRQDLYPALKGVN--TVFHCASPPP--SSNNKEL-FYRVNYIGTKNVIETCKE 134
           F   D+  +  L    K  +   V H A       S  K L +YRVN  GT  ++E  K 
Sbjct: 62  FEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKA 121

Query: 135 AGVQKLILTSSASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE 190
            GV+ L+ +SSA+V     +  +D  + T          + Y ++K   E  +      +
Sbjct: 122 HGVKNLVFSSSATVYGNPQYLPLDEAHPTGGC------TNPYGKSKFFIEEMIRDLCQAD 175

Query: 191 KN--------FLTTAIRPHGIFGPRDPQ-----LVPILIEAARNGKMKF-VIGNGKNLVD 236
           K         F  T     G  G  DPQ     L+P + + A   +    V GN  +  D
Sbjct: 176 KTWNAVLLRYFNPTGAHASGCIG-EDPQGIPNNLMPYVSQVAIGRREALNVFGNDYDTED 234

Query: 237 FTFVENVVH------GHILAAEQL 254
            T V + +H      GHI A  +L
Sbjct: 235 GTGVRDYIHVVDLAKGHIAALRKL 258


>gi|33519455 methionine adenosyltransferase II, beta isoform 2 [Homo
           sapiens]
          Length = 323

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 38/171 (22%), Positives = 78/171 (45%), Gaps = 15/171 (8%)

Query: 23  PKVNADIEKVNQN-QAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFF 81
           P++  D+E+   N   +R  V G +G LG+ + ++     +      +  GF   + +F 
Sbjct: 2   PEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFE 57

Query: 82  LGDLCSRQDLYPALKGV--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAG 136
             +L     ++  +     + + HCA+   P    N  +   ++N   + N+ +  + A 
Sbjct: 58  QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAA 115

Query: 137 VQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
           V   ++  S+  +F+G +     ED+P    P++ Y +TK+  E+AVL  N
Sbjct: 116 VGAFLIYISSDYVFDGTNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 163


>gi|11034825 methionine adenosyltransferase II, beta isoform 1 [Homo
           sapiens]
          Length = 334

 Score = 36.6 bits (83), Expect = 0.037
 Identities = 34/155 (21%), Positives = 70/155 (45%), Gaps = 14/155 (9%)

Query: 38  KRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFFLGDLCSRQDLYPALKG 97
           +R  V G +G LG+ + ++     +      +  GF   + +F   +L     ++  +  
Sbjct: 29  RRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFEQVNLLDSNAVHHIIHD 84

Query: 98  V--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVIFEG 152
              + + HCA+   P    N  +   ++N   + N+ +  + A V   ++  S+  +F+G
Sbjct: 85  FQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVFDG 142

Query: 153 VDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
            +     ED+P    P++ Y +TK+  E+AVL  N
Sbjct: 143 TNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 174


>gi|169163903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 113

 Score = 32.3 bits (72), Expect = 0.71
 Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 25/111 (22%)

Query: 17  HLTEDTPK-VNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN 75
           HL +D PK    D+E V Q            GF G H V  ++ + +   V      F  
Sbjct: 21  HLLDDQPKGEGGDVEHVQQR-----------GFAGSHFVSMVIPKAWKKEV------FSG 63

Query: 76  PQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTK 126
           P+  F+ G + S   + PA     T+        +SN   +  R + + TK
Sbjct: 64  PRPVFWAGTVTSHGAMAPARAAAGTLL-------ASNMSLISVRSSLVNTK 107


>gi|239747712 PREDICTED: hypothetical protein XP_002348233 [Homo
           sapiens]
          Length = 113

 Score = 32.3 bits (72), Expect = 0.71
 Identities = 28/111 (25%), Positives = 43/111 (38%), Gaps = 25/111 (22%)

Query: 17  HLTEDTPK-VNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN 75
           HL +D PK    D+E V Q            GF G H V  ++ + +   V      F  
Sbjct: 21  HLLDDQPKGEGGDVEHVQQR-----------GFAGSHFVSMVIPKAWKKEV------FSG 63

Query: 76  PQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTK 126
           P+  F+ G + S   + PA     T+        +SN   +  R + + TK
Sbjct: 64  PRPVFWAGTVTSHGAMAPARAAAGTLL-------ASNMSLISVRSSLVNTK 107


>gi|6681764 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9,
           39kDa [Homo sapiens]
          Length = 377

 Score = 32.3 bits (72), Expect = 0.71
 Identities = 52/237 (21%), Positives = 94/237 (39%), Gaps = 42/237 (17%)

Query: 41  TVIGGSGFLGQHMVEQLLARGYAV---------NVFDIQQGFDNPQVRFFLGDLCSRQDL 91
           TV G +GFLG+++V  L   G  V         ++  ++   D  Q+ F   D   +  +
Sbjct: 57  TVFGATGFLGRYVVNHLGRMGSQVIIPYRCDKYDIMHLRPMGDLGQLLFLEWDARDKDSI 116

Query: 92  YPALKGVNTVFHCASPPPSSNN---KELFYRVNYIGTKNVIETCKEAGVQKLILTSSASV 148
              ++  N V +       + N   +++F ++     + + +  KEAGV+K I  S  + 
Sbjct: 117 RRVVQHSNVVINLIGRDWETKNFDFEDVFVKI----PQAIAQLSKEAGVEKFIHVSHLN- 171

Query: 149 IFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPEKNFLTTAIRPHGIFGPRD 208
                +IK+ +            Y   K + E+ V  A  PE       ++P  IFG R+
Sbjct: 172 ----ANIKSSSR-----------YLRNKAVGEKVVRDA-FPE----AIIVKPSDIFG-RE 210

Query: 209 PQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDSTLGGKAF 265
            + +       R G +       K +    +V +V  G + A     +D    GK+F
Sbjct: 211 DRFLNSFASMHRFGPIPLGSLGWKTVKQPVYVVDVSKGIVNAV----KDPDANGKSF 263


>gi|40068481 SET domain containing 3 isoform a [Homo sapiens]
          Length = 594

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 14/43 (32%), Positives = 20/43 (46%)

Query: 237 FTFVENVVHGHILAAEQLSRDSTLGGKAFHITNDEPIPFWTFL 279
           F   E  +  H+L    + R  TLG   F ++ D  +  WTFL
Sbjct: 388 FCMTEEELKEHLLGDSAIDRIFTLGNSEFPVSWDNEVKLWTFL 430


>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
          Length = 323

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
           P   N K LF  V+   T   +E CK+AG+ K I  S+
Sbjct: 130 PKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSN 167


>gi|239741578 PREDICTED: hypothetical protein XP_002342256 [Homo
           sapiens]
          Length = 113

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 27/111 (24%), Positives = 43/111 (38%), Gaps = 25/111 (22%)

Query: 17  HLTEDTPK-VNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN 75
           +L +D PK    D+E V Q            GF G H V  ++ + +   V      F  
Sbjct: 21  YLLDDQPKGEGGDVEHVQQR-----------GFAGSHFVSMVIPKAWKKEV------FSG 63

Query: 76  PQVRFFLGDLCSRQDLYPALKGVNTVFHCASPPPSSNNKELFYRVNYIGTK 126
           P+  F+ G + S   + PA     T+        +SN   +  R + + TK
Sbjct: 64  PRPVFWAGTVTSHGAMAPARAAAGTLL-------ASNMSLISVRSSLVNTK 107


>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
          Length = 326

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 21/75 (28%), Positives = 39/75 (52%), Gaps = 3/75 (4%)

Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSAS-VIFEGVDIKNGTEDLPYA- 165
           P   N K L+++ N   T   +E CK+AG+ K +  S+ +    E +  K G +  P + 
Sbjct: 133 PRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSN 192

Query: 166 -MKPIDYYTETKILQ 179
            ++   Y+T+ K+L+
Sbjct: 193 QVECHPYFTQPKLLK 207


>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
          Length = 323

 Score = 30.0 bits (66), Expect = 3.5
 Identities = 15/38 (39%), Positives = 21/38 (55%)

Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
           P   N K +F  V+   T  V+E CK+AG+ K I  S+
Sbjct: 130 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSN 167


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 23/86 (26%), Positives = 40/86 (46%), Gaps = 7/86 (8%)

Query: 14  ARTHLTEDTP-KVNADIEKVNQNQAKRCTVIGGS-GFLGQHMVEQLLARGYAVNVFDIQQ 71
           A +   ED   ++N  +E+VN+  AK   V G     +    ++++LA     N  +I  
Sbjct: 651 ANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILA-----NYQEIVF 705

Query: 72  GFDNPQVRFFLGDLCSRQDLYPALKG 97
              +PQ +  + + C RQD   A+ G
Sbjct: 706 ARTSPQQKLIIVEGCQRQDAVVAVTG 731


>gi|115430219 lambda-crystallin [Homo sapiens]
          Length = 319

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 13/37 (35%), Positives = 21/37 (56%)

Query: 35 NQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQ 71
          + A  C VI GSG +G+       + G+ V ++DI+Q
Sbjct: 3  SSAAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQ 39


>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
           P   N K LF  V+   T   +E CK+AG+ K I  S+
Sbjct: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167


>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 108 PPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSS 145
           P   N K LF  V+   T   +E CK+AG+ K I  S+
Sbjct: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSN 167


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,000,212
Number of Sequences: 37866
Number of extensions: 600689
Number of successful extensions: 1233
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1178
Number of HSP's gapped (non-prelim): 37
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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