Guide to the Human Genome
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Search of human proteins with 191252812

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|191252812 target of myb1-like 1 [Homo sapiens]
         (476 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|191252812 target of myb1-like 1 [Homo sapiens]                     948   0.0  
gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens]           252   5e-67
gi|209180457 target of myb1 isoform 2 [Homo sapiens]                  234   1e-61
gi|4885637 target of myb1 isoform 1 [Homo sapiens]                    234   1e-61
gi|209180448 target of myb1 isoform 3 [Homo sapiens]                  210   3e-54
gi|209180450 target of myb1 isoform 4 [Homo sapiens]                  209   6e-54
gi|75677327 target of myb1-like 2 isoform 1 [Homo sapiens]            187   2e-47
gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]    95   2e-19
gi|20336267 ADP-ribosylation factor binding protein 3 isoform lo...    94   3e-19
gi|9558729 golgi associated, gamma adaptin ear containing, ARF b...    83   5e-16
gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]      81   2e-15
gi|48527952 golgi associated, gamma adaptin ear containing, ARF ...    80   4e-15
gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]        76   8e-14
gi|4758528 hepatocyte growth factor-regulated tyrosine kinase su...    61   2e-09
gi|14719400 ADP-ribosylation factor binding protein 3 isoform sh...    60   6e-09
gi|4504063 golgin 97 [Homo sapiens]                                    39   0.013
gi|24797108 calcium-binding tyrosine phosphorylation-regulated p...    37   0.030
gi|148839305 structural maintenance of chromosomes flexible hing...    37   0.030
gi|24797114 calcium-binding tyrosine phosphorylation-regulated p...    37   0.039
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         35   0.15 
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         35   0.15 
gi|197313748 SET domain containing 2 [Homo sapiens]                    33   0.43 
gi|197276594 RNA binding motif protein 20 [Homo sapiens]               33   0.43 
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo...    33   0.43 
gi|124248539 axin interactor, dorsalization associated [Homo sap...    33   0.57 
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo...    33   0.57 
gi|109715849 chromosome 6 open reading frame 204 isoform b [Homo...    33   0.57 
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s...    33   0.74 
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa...    33   0.74 
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 32   0.97 

>gi|191252812 target of myb1-like 1 [Homo sapiens]
          Length = 476

 Score =  948 bits (2450), Expect = 0.0
 Identities = 476/476 (100%), Positives = 476/476 (100%)

Query: 1   MAFGKSHRDPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRI 60
           MAFGKSHRDPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRI
Sbjct: 1   MAFGKSHRDPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRI 60

Query: 61  SKNYNHKEIQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRIL 120
           SKNYNHKEIQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRIL
Sbjct: 61  SKNYNHKEIQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRIL 120

Query: 121 NFIKTWSQGFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQISSNPPTSVPT 180
           NFIKTWSQGFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQISSNPPTSVPT
Sbjct: 121 NFIKTWSQGFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQISSNPPTSVPT 180

Query: 181 APALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQ 240
           APALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQ
Sbjct: 181 APALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQ 240

Query: 241 KLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQ 300
           KLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQ
Sbjct: 241 KLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQ 300

Query: 301 KEATNTTSEPSAPSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNFSLPSSDVTNNLKPS 360
           KEATNTTSEPSAPSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNFSLPSSDVTNNLKPS
Sbjct: 301 KEATNTTSEPSAPSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNFSLPSSDVTNNLKPS 360

Query: 361 LHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQS 420
           LHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQS
Sbjct: 361 LHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQS 420

Query: 421 LPPLPSNHPAMTKSDLQPPNYYEVMEFDPLAPAVTTEAIYEEIDAHQHKGAQNDGD 476
           LPPLPSNHPAMTKSDLQPPNYYEVMEFDPLAPAVTTEAIYEEIDAHQHKGAQNDGD
Sbjct: 421 LPPLPSNHPAMTKSDLQPPNYYEVMEFDPLAPAVTTEAIYEEIDAHQHKGAQNDGD 476


>gi|131888135 target of myb1-like 2 isoform 3 [Homo sapiens]
          Length = 507

 Score =  252 bits (644), Expect = 5e-67
 Identities = 146/386 (37%), Positives = 223/386 (57%), Gaps = 41/386 (10%)

Query: 9   DPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKE 68
           +P++T VG  +EKAT   +Q+EDW   M ICDIIN T++GPKDA++ALKKR++ N N++E
Sbjct: 7   NPFSTPVGQCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYRE 66

Query: 69  IQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQ 128
           + L L++++ CV+NCG  F  L+  ++F+   LVK+++P+ N P  +Q+++L  I+ W+ 
Sbjct: 67  VMLALTVLETCVKNCGHRFHILVANRDFIDSVLVKIISPKNNPPTIVQDKVLALIQAWAD 126

Query: 129 GFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEA------------------------ETAR 164
            F    D++ V  +Y +L +KGV+FP ++ +A                           R
Sbjct: 127 AFRSSPDLTGVVHIYEELKRKGVEFPMADLDALSPIHTPQRSVPEVDPAATMPRSQSQQR 186

Query: 165 QETAQISSNPPT--SVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAI 222
                 SS PP   S P APAL SV  P    +T   EQI +L SELD+V+ N +VMS +
Sbjct: 187 TSAGSYSSPPPAPYSAPQAPAL-SVTGP----ITANSEQIARLRSELDVVRGNTKVMSEM 241

Query: 223 LMENTPGSENHEDIELLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILG 282
           L E  PG E+  D+ELLQ+L +T R MQ+RI++L+  V NE+VT EL+ VN+DLNN  L 
Sbjct: 242 LTEMVPGQEDSSDLELLQELNRTCRAMQQRIVELISRVSNEEVTEELLHVNDDLNNVFLR 301

Query: 283 YERFTRNQQRILEQNKNQKEATNTTSEPSAPSQDLLDLSP-SPRMPRATLGEL---NTMN 338
           YERF R +     QN +       T +      +L+DL P SP +    +G     ++++
Sbjct: 302 YERFERYRSGRSVQNASNGVLNEVTED------NLIDLGPGSPAVVSPMVGNTAPPSSLS 355

Query: 339 NQLSGLNFSLPSSDVTNNLKPSLHPQ 364
           +QL+GL+    S   T +     +P+
Sbjct: 356 SQLAGLDLGTESVSGTLSSLQQCNPR 381


>gi|209180457 target of myb1 isoform 2 [Homo sapiens]
          Length = 493

 Score =  234 bits (598), Expect = 1e-61
 Identities = 140/369 (37%), Positives = 212/369 (57%), Gaps = 40/369 (10%)

Query: 9   DPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKE 68
           +P+++ VG  IEKAT   +Q+EDW   M ICDIIN T++GPKDA++A+KKRI  N N  E
Sbjct: 7   NPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHE 66

Query: 69  IQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQ 128
           + L L++++ CV+NCG  F  L+  ++FV+  LV+ + P+ N P  + +++LN I++W+ 
Sbjct: 67  VMLALTVLETCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQSWAD 126

Query: 129 GFPGGVDVSEVKEVYLDLVKKGVQFPPSE----------------AEAETARQETAQISS 172
            F    D++ V  +Y DL +KG++FP ++                +E ++ +      SS
Sbjct: 127 AFRSSPDLTGVVTIYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSS 186

Query: 173 NPPTSVP-TAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSE 231
               S    AP  +  I   ++ +   PEQIGKL SEL+MV  NVRVMS +L E  P   
Sbjct: 187 QQEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQA 246

Query: 232 NHEDIELLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQ 291
              D+ELLQ+L +T R MQ+R+++L+  + NE +T EL+ VN++LNN  L +ERF R + 
Sbjct: 247 EPADLELLQELNRTCRAMQQRVLELIPQIANEQLTEELLIVNDNLNNVFLRHERFERFR- 305

Query: 292 RILEQNKNQKEATNTTSEPSA--PSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNFSLP 349
                         TT  PS   P+ DL+D+ P P    A  G L   ++QL+G+N  L 
Sbjct: 306 -----------TGQTTKAPSEAEPAADLIDMGPDP----AATGNL---SSQLAGMN--LG 345

Query: 350 SSDVTNNLK 358
           SS V   L+
Sbjct: 346 SSSVRAGLQ 354


>gi|4885637 target of myb1 isoform 1 [Homo sapiens]
          Length = 492

 Score =  234 bits (598), Expect = 1e-61
 Identities = 140/369 (37%), Positives = 212/369 (57%), Gaps = 40/369 (10%)

Query: 9   DPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKE 68
           +P+++ VG  IEKAT   +Q+EDW   M ICDIIN T++GPKDA++A+KKRI  N N  E
Sbjct: 7   NPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHE 66

Query: 69  IQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQ 128
           + L L++++ CV+NCG  F  L+  ++FV+  LV+ + P+ N P  + +++LN I++W+ 
Sbjct: 67  VMLALTVLETCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQSWAD 126

Query: 129 GFPGGVDVSEVKEVYLDLVKKGVQFPPSE----------------AEAETARQETAQISS 172
            F    D++ V  +Y DL +KG++FP ++                +E ++ +      SS
Sbjct: 127 AFRSSPDLTGVVTIYEDLRRKGLEFPMTDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSS 186

Query: 173 NPPTSVP-TAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSE 231
               S    AP  +  I   ++ +   PEQIGKL SEL+MV  NVRVMS +L E  P   
Sbjct: 187 QQEDSGQHAAPLPAPPILSGDTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQA 246

Query: 232 NHEDIELLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQ 291
              D+ELLQ+L +T R MQ+R+++L+  + NE +T EL+ VN++LNN  L +ERF R + 
Sbjct: 247 EPADLELLQELNRTCRAMQQRVLELIPQIANEQLTEELLIVNDNLNNVFLRHERFERFR- 305

Query: 292 RILEQNKNQKEATNTTSEPSA--PSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNFSLP 349
                         TT  PS   P+ DL+D+ P P    A  G L   ++QL+G+N  L 
Sbjct: 306 -----------TGQTTKAPSEAEPAADLIDMGPDP----AATGNL---SSQLAGMN--LG 345

Query: 350 SSDVTNNLK 358
           SS V   L+
Sbjct: 346 SSSVRAGLQ 354


>gi|209180448 target of myb1 isoform 3 [Homo sapiens]
          Length = 460

 Score =  210 bits (534), Expect = 3e-54
 Identities = 128/342 (37%), Positives = 194/342 (56%), Gaps = 40/342 (11%)

Query: 36  MHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDMCVQNCGPSFQSLIVKKE 95
           M ICDIIN T++GPKDA++A+KKRI  N N  E+ L L++++ CV+NCG  F  L+  ++
Sbjct: 1   MEICDIINETEEGPKDALRAVKKRIVGNKNFHEVMLALTVLETCVKNCGHRFHVLVASQD 60

Query: 96  FVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGVDVSEVKEVYLDLVKKGVQFPP 155
           FV+  LV+ + P+ N P  + +++LN I++W+  F    D++ V  +Y DL +KG++FP 
Sbjct: 61  FVESVLVRTILPKNNPPTIVHDKVLNLIQSWADAFRSSPDLTGVVTIYEDLRRKGLEFPM 120

Query: 156 SE----------------AEAETARQETAQISSNPPTSVP-TAPALSSVIAPKNSTVTLV 198
           ++                +E ++ +      SS    S    AP  +  I   ++ +   
Sbjct: 121 TDLDMLSPIHTPQRTVFNSETQSGQDSVGTDSSQQEDSGQHAAPLPAPPILSGDTPIAPT 180

Query: 199 PEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQKLYKTGREMQERIMDLLV 258
           PEQIGKL SEL+MV  NVRVMS +L E  P      D+ELLQ+L +T R MQ+R+++L+ 
Sbjct: 181 PEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEPADLELLQELNRTCRAMQQRVLELIP 240

Query: 259 VVENEDVTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQKEATNTTSEPSA--PSQD 316
            + NE +T EL+ VN++LNN  L +ERF R +               TT  PS   P+ D
Sbjct: 241 QIANEQLTEELLIVNDNLNNVFLRHERFERFR------------TGQTTKAPSEAEPAAD 288

Query: 317 LLDLSPSPRMPRATLGELNTMNNQLSGLNFSLPSSDVTNNLK 358
           L+D+ P P    A  G L   ++QL+G+N  L SS V   L+
Sbjct: 289 LIDMGPDP----AATGNL---SSQLAGMN--LGSSSVRAGLQ 321


>gi|209180450 target of myb1 isoform 4 [Homo sapiens]
          Length = 447

 Score =  209 bits (531), Expect = 6e-54
 Identities = 131/352 (37%), Positives = 196/352 (55%), Gaps = 51/352 (14%)

Query: 9   DPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKE 68
           +P+++ VG  IEKAT   +Q+EDW   M ICDIIN T++GPKDA++A+KKRI  N N  E
Sbjct: 7   NPFSSPVGQRIEKATDGSLQSEDWALNMEICDIINETEEGPKDALRAVKKRIVGNKNFHE 66

Query: 69  IQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQ 128
           + L L++++ CV+NCG  F  L+  ++FV+  LV+ + P+ N P  + +++LN I+T   
Sbjct: 67  VMLALTVLETCVKNCGHRFHVLVASQDFVESVLVRTILPKNNPPTIVHDKVLNLIQT--- 123

Query: 129 GFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQISSNPPTSVPTAPALSSVI 188
                            +     Q        ++++QE +   + P   +P  P LS   
Sbjct: 124 -----------------VFNSETQSGQDSVGTDSSQQEDSGQHAAP---LPAPPILSG-- 161

Query: 189 APKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQKLYKTGRE 248
              ++ +   PEQIGKL SEL+MV  NVRVMS +L E  P      D+ELLQ+L +T R 
Sbjct: 162 ---DTPIAPTPEQIGKLRSELEMVSGNVRVMSEMLTELVPTQAEPADLELLQELNRTCRA 218

Query: 249 MQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQKEATNTTS 308
           MQ+R+++L+  + NE +T EL+ VN++LNN  L +ERF R +               TT 
Sbjct: 219 MQQRVLELIPQIANEQLTEELLIVNDNLNNVFLRHERFERFR------------TGQTTK 266

Query: 309 EPSA--PSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNFSLPSSDVTNNLK 358
            PS   P+ DL+D+ P P    A  G L   ++QL+G+N  L SS V   L+
Sbjct: 267 APSEAEPAADLIDMGPDP----AATGNL---SSQLAGMN--LGSSSVRAGLQ 309


>gi|75677327 target of myb1-like 2 isoform 1 [Homo sapiens]
          Length = 457

 Score =  187 bits (475), Expect = 2e-47
 Identities = 129/386 (33%), Positives = 189/386 (48%), Gaps = 91/386 (23%)

Query: 9   DPYATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKE 68
           +P++T VG  +EKAT   +Q+EDW   M ICDIIN T++GPKDA++ALKKR++ N N++E
Sbjct: 7   NPFSTPVGQCLEKATDGSLQSEDWTLNMEICDIINETEEGPKDAIRALKKRLNGNRNYRE 66

Query: 69  IQLTLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQ 128
           + L L+                                                   W+ 
Sbjct: 67  VMLALT--------------------------------------------------AWAD 76

Query: 129 GFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEA------------------------ETAR 164
            F    D++ V  +Y +L +KGV+FP ++ +A                           R
Sbjct: 77  AFRSSPDLTGVVHIYEELKRKGVEFPMADLDALSPIHTPQRSVPEVDPAATMPRSQSQQR 136

Query: 165 QETAQISSNPPT--SVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAI 222
                 SS PP   S P APALS V  P    +T   EQI +L SELD+V+ N +VMS +
Sbjct: 137 TSAGSYSSPPPAPYSAPQAPALS-VTGP----ITANSEQIARLRSELDVVRGNTKVMSEM 191

Query: 223 LMENTPGSENHEDIELLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILG 282
           L E  PG E+  D+ELLQ+L +T R MQ+RI++L+  V NE+VT EL+ VN+DLNN  L 
Sbjct: 192 LTEMVPGQEDSSDLELLQELNRTCRAMQQRIVELISRVSNEEVTEELLHVNDDLNNVFLR 251

Query: 283 YERFTRNQQRILEQNKNQKEATNTTSEPSAPSQDLLDLSP-SPRMPRATLGEL---NTMN 338
           YERF R +     QN +       T +      +L+DL P SP +    +G     ++++
Sbjct: 252 YERFERYRSGRSVQNASNGVLNEVTED------NLIDLGPGSPAVVSPMVGNTAPPSSLS 305

Query: 339 NQLSGLNFSLPSSDVTNNLKPSLHPQ 364
           +QL+GL+    S   T +     +P+
Sbjct: 306 SQLAGLDLGTESVSGTLSSLQQCNPR 331


>gi|9558751 ADP-ribosylation factor binding protein 2 [Homo sapiens]
          Length = 613

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 74/299 (24%), Positives = 145/299 (48%), Gaps = 34/299 (11%)

Query: 12  ATSVGHLIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQL 71
           A S+   + KAT   +  +DW    + C+ +NT  +GP  A   L  +I ++   KE   
Sbjct: 23  AASLELWLNKATDPSMSEQDWSAIQNFCEQVNTDPNGPTHAPWLLAHKI-QSPQEKEALY 81

Query: 72  TLSLIDMCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYN---LPLDIQNRILNFIKTWSQ 128
            L++++MC+ +CG  F S + K  F+ E L+K+L+P+Y        ++ R++  + +W+ 
Sbjct: 82  ALTVLEMCMNHCGEKFHSEVAKFRFLNE-LIKVLSPKYLGSWATGKVKGRVIEILFSWTV 140

Query: 129 GFPGGVDVSEVKEVYLDLVKKG------------VQFPPS--------EAEAETARQETA 168
            FP  +   ++++ Y  L K+G            +  PPS        +A+ E ++  T 
Sbjct: 141 WFPEDI---KIRDAYQMLKKQGIIKQDPKLPVDKILPPPSPWPKSSIFDADEEKSKLLTR 197

Query: 169 QISSNPPTSVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAIL-MENT 227
            + SN P  +  A  L   +  +    +   E++ K  S ++ V+ +V+V+  +L M   
Sbjct: 198 LLKSNHPEDLQAANRLIKNLVKEEQEKS---EKVSKRVSAVEEVRSHVKVLQEMLSMYRR 254

Query: 228 PGSENHEDIELLQKLYKTGREMQERIMDLLV-VVENEDVTVELIQVNEDLNNAILGYER 285
           PG +   D E LQ +Y+   +++  +  L     +++D   E++Q N+ L   +L Y++
Sbjct: 255 PG-QAPPDQEALQVVYERCEKLRPTLFRLASDTTDDDDALAEILQANDLLTQGVLLYKQ 312


>gi|20336267 ADP-ribosylation factor binding protein 3 isoform long
           [Homo sapiens]
          Length = 723

 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 108/480 (22%), Positives = 209/480 (43%), Gaps = 93/480 (19%)

Query: 19  IEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDM 78
           + KAT    + EDW   +  CD IN   +GP+ AV+ L  +I      + +Q  L++++ 
Sbjct: 13  LNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQ-ALTVLEA 71

Query: 79  CVQNCGPSFQSLIVKKEFVKENLVKLLNPRY---NLPLDIQNRILNFIKTWSQGFPGGVD 135
           C++NCG  F + + K  F+ E L+K+++P+Y    +   ++ +++  + +W+   P   +
Sbjct: 72  CMKNCGRRFHNEVGKFRFLNE-LIKVVSPKYLGDRVSEKVKTKVIELLYSWTMALP---E 127

Query: 136 VSEVKEVYLDLVKKGV---------------QFPPSEAEAETARQETAQI------SSNP 174
            +++K+ Y  L ++G+                 PP         +E +++      S NP
Sbjct: 128 EAKIKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKSKNP 187

Query: 175 PTSVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHE 234
                    + S++    + +  V +   +LH+ L+ V  NVR++S +L+  +    +  
Sbjct: 188 DDLQEANKLIKSMVKEDEARIQKVTK---RLHT-LEEVNNNVRLLSEMLLHYSQEDSSDG 243

Query: 235 DIELLQKLYKTGREMQERIMDLLVVVENEDVTV-ELIQVNEDLNNAILGYERFTRNQ--- 290
           D EL+++L+      +  +  L    E+ D ++ +++Q +++L+  I  Y+     Q   
Sbjct: 244 DRELMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVIN 303

Query: 291 ----QRILEQNKNQKEATN-----------TTSE--------PSAPSQDLLDLSPSPRM- 326
                  L  ++   + +N           TT+         P+ PS  +  L P P+  
Sbjct: 304 GEVATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPPQAS 363

Query: 327 --PR--------ATLGELNTMNNQLSGLN---FSLPSSDVTNNLKP---SLHPQMNLLAL 370
             PR        ATLG  +T +N LS L+     L  +D   N+ P   + + Q +LL  
Sbjct: 364 GPPRSRSSSQAEATLGPSST-SNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQR 422

Query: 371 ENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNHPA 430
           E +++  F+ R       +         S++  LQP      +A  S+ S  PLP   PA
Sbjct: 423 EQSDLDFFSPRPGTAACGA---------SDAPLLQP------SAPSSSSSQAPLPPPFPA 467


>gi|9558729 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 101/440 (22%), Positives = 187/440 (42%), Gaps = 51/440 (11%)

Query: 19  IEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDM 78
           I +AT    +  DW      C+ +N   +GP  A + L  +I      + IQ  L++++ 
Sbjct: 14  INRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ-ALTVLET 72

Query: 79  CVQNCGPSFQSLIVKKEFVKENLVKLLNPRY---NLPLDIQNRILNFIKTWSQGFPGGVD 135
           C+++CG  F   + K  F+ E L+K+++P+Y        ++N+IL  + +W+ G P  V 
Sbjct: 73  CMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPEEV- 130

Query: 136 VSEVKEVYLDLVKKGV-------------QFPPSE------AEAETARQETAQISSNPPT 176
             ++ E Y  L K+G+               PP         + E ++     + S+ P 
Sbjct: 131 --KIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSHPE 188

Query: 177 SVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDI 236
            +  A  L   +  ++       E+I K  + ++ V  NV++++ ++M ++ G       
Sbjct: 189 DLRAANKLIKEMVQEDQKRM---EKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSS 245

Query: 237 E-LLQKLYKTGREMQERIMDLLVVVE-NEDVTVELIQVNEDLNNAILGYERFTRNQQRIL 294
           E L+++LY+    M+  +  L    E N++   E++Q N++L   I  Y++  R +    
Sbjct: 246 EDLMKELYQRCERMRPTLFRLASDTEDNDEALAEILQANDNLTQVINLYKQLVRGE---- 301

Query: 295 EQNKNQKEATNTTSEPSAPSQDLLDLSPS----PRMP-----RATLGELNTMNNQLSGLN 345
           E N +    +   S  +      LDL P+    P MP     +A+  + +   + L    
Sbjct: 302 EVNGDATAGSIPGSTSALLDLSGLDLPPAGTTYPAMPTRPGEQASPEQPSASVSLLDDEL 361

Query: 346 FSLPSSDVTNNLKPSLHPQ--MNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVF 403
            SL  SD T    PSL      +  + + TE P  A   + ++ S       L  S+ + 
Sbjct: 362 MSLGLSDPTPPSGPSLDGTGWNSFQSSDATEPPAPALAQAPSMESRPPAQTSLPASSGL- 420

Query: 404 LQPVSLQTIAAAPSNQSLPP 423
                L  +      QSLPP
Sbjct: 421 ---DDLDLLGKTLLQQSLPP 437



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 19/149 (12%)

Query: 327 PRATLGELNTMNNQLSGLNFSLPSSDVTNNLKPSLHPQMNL---LALENTEIPPFAQRTS 383
           PR TL +L   ++  S  + S  S   T + +P   PQ  +   L+L +  +P  + + S
Sbjct: 451 PRLTLRDLQNKSSSCSSPSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPS 510

Query: 384 QNLTSSHAYDNF------------LEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNHPAM 431
            N+     YD              L   + V +  VS+ + A  P    +    S  P +
Sbjct: 511 -NILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIV--FQSAVPKV 567

Query: 432 TKSDLQPPNYYEVMEFDPLA-PAVTTEAI 459
            K  LQPP+  E+  F+P+  P+  T+ +
Sbjct: 568 MKVKLQPPSGTELPAFNPIVHPSAITQVL 596


>gi|188219625 signal transducing adaptor molecule 2 [Homo sapiens]
          Length = 525

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 85/356 (23%), Positives = 155/356 (43%), Gaps = 46/356 (12%)

Query: 19  IEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDM 78
           +EKAT     TEDW   M ICD + +T +G KD +KA+ KR++    H  +Q  L+L+  
Sbjct: 13  VEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPHVALQ-ALTLLGA 71

Query: 79  CVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGVDVSE 138
           CV NCG  F   +  ++F  E    + N  +     +  ++ + +  WS+ F      S 
Sbjct: 72  CVANCGKIFHLEVCSRDFATEVRAVIKNKAHP---KVCEKLKSLMVEWSEEFQKDPQFSL 128

Query: 139 VKEVYLDLVKKGVQFPPSEAEAETARQETAQISSNPPTSVPTAPALSSVIAPK----NST 194
           +      + ++G+ FPP+ ++  +A  +    S+        A A+   +  +      T
Sbjct: 129 ISATIKSMKEEGITFPPAGSQTVSAAAKNGTSSNKNKEDEDIAKAIELSLQEQKQQHTET 188

Query: 195 VTLVPEQIGKLHS----------ELDMVKMNVRVMS----AILMENTPGS----ENHEDI 236
            +L P    +L++          + + V+ N          I+++++  +    ENH  I
Sbjct: 189 KSLYPSSEIQLNNKVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWWKGENHRGI 248

Query: 237 ELLQKLYKTGR---EMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRI 293
            L    + T     E +   +D L V++++   VE I+ +E      +  ++  R  Q +
Sbjct: 249 GLFPSNFVTTNLNIETEAAAVDKLNVIDDD---VEEIKKSEP-EPVYIDEDKMDRALQVL 304

Query: 294 LEQNKNQKEATNTTSEPSAPSQDLLDLSPSPR----MPRATLGELNTMNNQLSGLN 345
                  +    T S+P   SQDLLDL    +    M    L E++  +++LS LN
Sbjct: 305 -------QSIDPTDSKPD--SQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELN 351


>gi|48527952 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 2 [Homo sapiens]
          Length = 552

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 109/512 (21%), Positives = 203/512 (39%), Gaps = 87/512 (16%)

Query: 19  IEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDM 78
           I +AT    +  DW      C+ +N   +GP  A + L  +I      + IQ  L++++ 
Sbjct: 14  INRATNPLNKELDWASINGFCEQLNEDFEGPPLATRLLAHKIQSPQEWEAIQ-ALTVLET 72

Query: 79  CVQNCGPSFQSLIVKKEFVKENLVKLLNPRY---NLPLDIQNRILNFIKTWSQGFPGGVD 135
           C+++CG  F   + K  F+ E L+K+++P+Y        ++N+IL  + +W+ G P  V 
Sbjct: 73  CMKSCGKRFHDEVGKFRFLNE-LIKVVSPKYLGSRTSEKVKNKILELLYSWTVGLPEEV- 130

Query: 136 VSEVKEVYLDLVKKGV-------------QFPPSE------AEAETARQETAQISSNPPT 176
             ++ E Y  L K+G+               PP         + E ++     + S+ P 
Sbjct: 131 --KIAEAYQMLKKQGIVKSDPKLPDDTTFPLPPPRPKNVIFEDEEKSKMLARLLKSSHPE 188

Query: 177 SVPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDI 236
            +  A  L   +  ++       E+I K  + ++ V  NV++++ ++M ++ G       
Sbjct: 189 DLRAANKLIKEMVQEDQKRM---EKISKRVNAIEEVNNNVKLLTEMVMSHSQGGAAAGSS 245

Query: 237 E-LLQKLYKTGREMQERIMDLLVVVENEDVTVELIQVNEDLNNAI--LGYERFTRNQ--- 290
           E L+++LY+    M+  +  L    E+ D  + L         ++   G+  F  +    
Sbjct: 246 EDLMKELYQRCERMRPTLFRLASDTEDNDEALGLSDPTPPSGPSLDGTGWNSFQSSDATE 305

Query: 291 ---QRILEQNKNQKEATNTTSEPSAPSQDLLDL-------------------SPSPRMPR 328
                + +    +      TS P++   D LDL                         PR
Sbjct: 306 PPAPALAQAPSMESRPPAQTSLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPR 365

Query: 329 ATLGELNTMNNQLSGLNFSLPSSDVTNNL--------KPSLHPQMNLLALENTEIPPFAQ 380
            TL +L   ++  S      PSS  T+ L        +P   P    L+L +  +P  + 
Sbjct: 366 LTLRDLQNKSSSCSS-----PSSSATSLLHTVSPEPPRPPQQPVPTELSLASITVPLESI 420

Query: 381 RTSQNLTSSHAYDNF------------LEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNH 428
           + S N+     YD              L   + V +  VS+ + A  P    +    S  
Sbjct: 421 KPS-NILPVTVYDQHGFRILFHFARDPLPGRSDVLVVVVSMLSTAPQPIRNIV--FQSAV 477

Query: 429 PAMTKSDLQPPNYYEVMEFDPLA-PAVTTEAI 459
           P + K  LQPP+  E+  F+P+  P+  T+ +
Sbjct: 478 PKVMKVKLQPPSGTELPAFNPIVHPSAITQVL 509


>gi|4507249 signal transducing adaptor molecule 1 [Homo sapiens]
          Length = 540

 Score = 75.9 bits (185), Expect = 8e-14
 Identities = 44/161 (27%), Positives = 83/161 (51%), Gaps = 10/161 (6%)

Query: 19  IEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDM 78
           +EKAT      EDWG  + ICD +  ++ GPKD ++++ +R++    H  +Q  L+L+  
Sbjct: 13  VEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQ-ALTLLGA 71

Query: 79  CVQNCGPSFQSLIVKKEFVKE--NLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGVDV 136
           CV NCG  F   +  ++F  E  N++   +P+      +  ++   +  W+  F     +
Sbjct: 72  CVSNCGKIFHLEVCSRDFASEVSNVLNKGHPK------VCEKLKALMVEWTDEFKNDPQL 125

Query: 137 SEVKEVYLDLVKKGVQFPPSEAE-AETARQETAQISSNPPT 176
           S +  +  +L ++GV FP   ++ AE A+   A ++ +P T
Sbjct: 126 SLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGT 166


>gi|4758528 hepatocyte growth factor-regulated tyrosine kinase
           substrate [Homo sapiens]
          Length = 777

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 37/137 (27%), Positives = 70/137 (51%), Gaps = 4/137 (2%)

Query: 18  LIEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLID 77
           L++KAT   +   DW   + ICD+I       K AV ++KK+++    H  +   L +++
Sbjct: 11  LLDKATSQLLLETDWESILQICDLIRQGDTQAKYAVNSIKKKVNDKNPHVAL-YALEVME 69

Query: 78  MCVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGVDVS 137
             V+NCG +    +  K+ ++E L  LL  +  + ++++N+IL  I+ W+  F       
Sbjct: 70  SVVKNCGQTVHDEVANKQTMEE-LKDLL--KRQVEVNVRNKILYLIQAWAHAFRNEPKYK 126

Query: 138 EVKEVYLDLVKKGVQFP 154
            V++ Y  +  +G  FP
Sbjct: 127 VVQDTYQIMKVEGHVFP 143


>gi|14719400 ADP-ribosylation factor binding protein 3 isoform short
           [Homo sapiens]
          Length = 690

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 97/477 (20%), Positives = 184/477 (38%), Gaps = 120/477 (25%)

Query: 19  IEKATFAGVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEIQLTLSLIDM 78
           + KAT    + EDW   +  CD IN   +GP+ AV+ L  +I      + +Q    L D 
Sbjct: 13  LNKATNPSNRQEDWEYIIGFCDQINKELEGPQIAVRLLAHKIQSPQEWEALQALTYLGDR 72

Query: 79  CVQNCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGVDVSE 138
             +                                 ++ +++  + +W+   P   + ++
Sbjct: 73  VSEK--------------------------------VKTKVIELLYSWTMALP---EEAK 97

Query: 139 VKEVYLDLVKKGV---------------QFPPSEAEAETARQETAQI------SSNPPTS 177
           +K+ Y  L ++G+                 PP         +E +++      S NP   
Sbjct: 98  IKDAYHMLKRQGIVQSDPPIPVDRTLIPSPPPRPKNPVFDDEEKSKLLAKLLKSKNPDDL 157

Query: 178 VPTAPALSSVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIE 237
                 + S++    + +  V +   +LH+ L+ V  NVR++S +L+  +    +  D E
Sbjct: 158 QEANKLIKSMVKEDEARIQKVTK---RLHT-LEEVNNNVRLLSEMLLHYSQEDSSDGDRE 213

Query: 238 LLQKLYKTGREMQERIMDLLVVVENEDVTV-ELIQVNEDLNNAILGYERFTRNQ------ 290
           L+++L+      +  +  L    E+ D ++ +++Q +++L+  I  Y+     Q      
Sbjct: 214 LMKELFDQCENKRRTLFKLASETEDNDNSLGDILQASDNLSRVINSYKTIIEGQVINGEV 273

Query: 291 -QRILEQNKNQKEATN-----------TTSE--------PSAPSQDLLDLSPSPRM---P 327
               L  ++   + +N           TT+         P+ PS  +  L P P+    P
Sbjct: 274 ATLTLPDSEGNSQCSNQGTLIDLAELDTTNSLSSVLAPAPTPPSSGIPILPPPPQASGPP 333

Query: 328 R--------ATLGELNTMNNQLSGLN---FSLPSSDVTNNLKP---SLHPQMNLLALENT 373
           R        ATLG  +T +N LS L+     L  +D   N+ P   + + Q +LL  E +
Sbjct: 334 RSRSSSQAEATLGPSST-SNALSWLDEELLCLGLADPAPNVPPKESAGNSQWHLLQREQS 392

Query: 374 EIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQSLPPLPSNHPA 430
           ++  F+ R       +         S++  LQP      +A  S+ S  PLP   PA
Sbjct: 393 DLDFFSPRPGTAACGA---------SDAPLLQP------SAPSSSSSQAPLPPPFPA 434


>gi|4504063 golgin 97 [Homo sapiens]
          Length = 767

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 49/245 (20%), Positives = 102/245 (41%), Gaps = 38/245 (15%)

Query: 200 EQIGKLHSELDMVKMNV-RVMSAILMENTPGSENHEDIELLQKLY-------------KT 245
           E +GK+  EL+     + R    ++  N   S+  + +E LQ+ Y             KT
Sbjct: 193 ESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKT 252

Query: 246 GRE-----MQERIMDLLVVVENEDVTVELIQV-NEDLNNAILGYERFTRNQQRILEQN-K 298
           G E     ++++  +L  +++   + ++ +    ++  + I   +    + ++ LEQN  
Sbjct: 253 GAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLS 312

Query: 299 NQKEATNTTSEPSAPSQDLLDLSPSPRMPRATLGE-LNTMNNQLSGLNFSLPSSDVTNNL 357
            ++       E +   Q+L D        R++  + +NT+  ++  L  +L +S+     
Sbjct: 313 GEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASE----- 367

Query: 358 KPSLHPQMNLLALENTEIPPFAQRTSQNLTSSHAY-------DNFLEHSNSVFLQPVSLQ 410
              L     ++A + T+I   A   + N  SSH           FLE + ++  Q V+L+
Sbjct: 368 -EQLQQSKGIVAAQETQIQELA---AANQESSHVQQQALALEQQFLERTQALEAQIVALE 423

Query: 411 TIAAA 415
              AA
Sbjct: 424 RTRAA 428


>gi|24797108 calcium-binding tyrosine phosphorylation-regulated
           protein isoform a [Homo sapiens]
          Length = 493

 Score = 37.4 bits (85), Expect = 0.030
 Identities = 44/203 (21%), Positives = 82/203 (40%), Gaps = 42/203 (20%)

Query: 95  EFVKENLVKLLNPRYNLPLDIQNRILNF----IKTWSQGF-----------PG------- 132
           +F      +L   R N  +DI++ +  F    ++ WS+G            PG       
Sbjct: 35  QFAAAYFQELTMYRGNTTMDIKDLVKQFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESK 94

Query: 133 -------GVDVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQ-ISSNPPTSVPTAPAL 184
                    D  E      +   K  QFP   A   T + E    +SS P T   T P  
Sbjct: 95  VPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPS 154

Query: 185 S---SVIAPKNSTVTLVPEQI-----GKLHS----ELDMVKMNVRVMSAILMENTPGSEN 232
           S   + ++P+ + V   P Q+     GK+ S    + D++ ++V     ++++  P SE 
Sbjct: 155 SPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEA 214

Query: 233 HEDIELLQKLYKTGREMQERIMD 255
            ED+ +   L  +G+ ++ ++++
Sbjct: 215 AEDVMVAAPLVCSGKVLEVQVVN 237


>gi|148839305 structural maintenance of chromosomes flexible hinge
            domain containing 1 [Homo sapiens]
          Length = 2005

 Score = 37.4 bits (85), Expect = 0.030
 Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 4/131 (3%)

Query: 176  TSVPTAPALSSVIAPKNSTVTLVPEQIGKLHS-ELDMVKMNVRVMSAILMENTPGSENHE 234
            T +     + + I   N   T  P  IGK+ + E   V  +  +MS +L E++PG ++ E
Sbjct: 1529 TGIDLVGTIIATIKGSNEEDTDTPLFIGKVRTLEFPFVNGSAEIMSLVLAESSPGRDSTE 1588

Query: 235  DIELLQ-KLYKTGREMQERIMDLLVV--VENEDVTVELIQVNEDLNNAILGYERFTRNQQ 291
               + + +L    R ++  I+  +    V+ +     L +  + L+ +I+ Y+      Q
Sbjct: 1589 YFIVFEPRLPLLSRTLEPYILPFMFYNDVKKQQQMAALTKEKDQLSQSIVMYKSLFEASQ 1648

Query: 292  RILEQNKNQKE 302
            ++L + K Q E
Sbjct: 1649 QLLNEMKCQVE 1659


>gi|24797114 calcium-binding tyrosine phosphorylation-regulated
           protein isoform b [Homo sapiens]
          Length = 475

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 32/134 (23%), Positives = 61/134 (45%), Gaps = 13/134 (9%)

Query: 135 DVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQ-ISSNPPTSVPTAPALS---SVIAP 190
           D  E      +   K  QFP   A   T + E    +SS P T   T P  S   + ++P
Sbjct: 86  DTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSP 145

Query: 191 KNSTVTLVPEQI-----GKLHS----ELDMVKMNVRVMSAILMENTPGSENHEDIELLQK 241
           + + V   P Q+     GK+ S    + D++ ++V     ++++  P SE  ED+ +   
Sbjct: 146 EFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAP 205

Query: 242 LYKTGREMQERIMD 255
           L  +G+ ++ ++++
Sbjct: 206 LVCSGKVLEVQVVN 219


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 5/101 (4%)

Query: 200 EQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQKLYKTGREMQERIMDLLVV 259
           E+  +L +E  ++K   + +  +L  +TP S+    I L     K+   + E+ +++L+ 
Sbjct: 768 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIE 827

Query: 260 VENEDVTVELIQVNEDL----NNAILGYERFTRNQQRILEQ 296
            ENED+  + IQ+NE++    N      + F  N Q + E+
Sbjct: 828 -ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEE 867


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 35.0 bits (79), Expect = 0.15
 Identities = 26/101 (25%), Positives = 51/101 (50%), Gaps = 5/101 (4%)

Query: 200 EQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQKLYKTGREMQERIMDLLVV 259
           E+  +L +E  ++K   + +  +L  +TP S+    I L     K+   + E+ +++L+ 
Sbjct: 768 EKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIKSKSKDSVWEKEIEILIE 827

Query: 260 VENEDVTVELIQVNEDL----NNAILGYERFTRNQQRILEQ 296
            ENED+  + IQ+NE++    N      + F  N Q + E+
Sbjct: 828 -ENEDLKQQCIQLNEEIEKQRNTFSFAEKNFEVNYQELQEE 867


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 69/349 (19%), Positives = 119/349 (34%), Gaps = 60/349 (17%)

Query: 128  QGFPGGVDVSEVKEVYLDLVKK--GVQFPPSEAEAETARQETAQISSNPPTSVPTAPALS 185
            +G  G  D+ +++ V ++  ++    Q  P +        ET   +S  PTS P A A  
Sbjct: 1901 EGKDGKEDLDQLENVPVEEEEELQSQQLLPQQLPECKVDSETNIEASKLPTSEPEADA-- 1958

Query: 186  SVIAPKNSTVTLVPEQIGKLHSELDMVKMNVRVMSAILMENTPGSENHEDIELLQKLYKT 245
              I PK S  T + E I                      E TP  +  E +  ++   + 
Sbjct: 1959 -EIEPKESNGTKLEEPIN---------------------EETPSQDEEEGVSDVES--ER 1994

Query: 246  GREMQERIMDLLVVVENEDVTVELIQVNEDLNNAILGYERFTRNQQRILEQNKNQKEATN 305
             +E  ++ +D+       D+  +L+   +DL               RI    K+Q E  N
Sbjct: 1995 SQEQPDKTVDI------SDLATKLLDSWKDLKEVY-----------RI--PKKSQTEKEN 2035

Query: 306  TTSEPSAPSQDLLDLSPSPRMP---RATLGELNTMNNQLSGLNFSL--PSSDVTNNLK-- 358
            TT+E    +    D +P+P+ P   R    +  T N +      SL  PSS      K  
Sbjct: 2036 TTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRSSLSPPSSAYERGTKRP 2095

Query: 359  ------PSLHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTI 412
                  P+   ++ +            +   Q +    A     +  N     P+   ++
Sbjct: 2096 DDRYDTPTSKKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQQQMQNLGMTSPLPYDSL 2155

Query: 413  AAAPSNQSLPPLPSNHPAMTKSDLQPPNYYEVMEFDPLAPAVTTEAIYE 461
                 +      P  +P     D   PN  +V+   P    V + A Y+
Sbjct: 2156 GYNAPHHPFAGYPPGYPMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYD 2204


>gi|197276594 RNA binding motif protein 20 [Homo sapiens]
          Length = 1227

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 36/138 (26%), Positives = 60/138 (43%), Gaps = 7/138 (5%)

Query: 321 SPSPRMPRATLGELNTMNNQLSGLNFSLPSSDVTNNLKPS--LHPQMNLLALENTEIPPF 378
           +P+P +P     +L  +  QL+     L  + VTNN   +  L+  ++ +A+     P F
Sbjct: 78  NPNPLLPSPASLQLAQLQAQLTLHRLKLAQTAVTNNTAAATVLNQVLSKVAMSQ---PLF 134

Query: 379 AQ-RTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQSLPPLPS-NHPAMTKSDL 436
            Q R    +T  H +    +H+ ++         IA +P +Q+  P PS N P    S +
Sbjct: 135 NQLRHPSVITGPHGHAGVPQHAAAIPSTRFPSNAIAFSPPSQTRGPGPSMNLPNQPPSAM 194

Query: 437 QPPNYYEVMEFDPLAPAV 454
               +  VM   P  PAV
Sbjct: 195 VMHPFTGVMPQTPGQPAV 212


>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
           sapiens]
          Length = 476

 Score = 33.5 bits (75), Expect = 0.43
 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 4/85 (4%)

Query: 121 NFIKT-WSQGFPGGVDVSEVKEVYLDLVKKGVQFPPSEAEAETARQETAQISSNPPTSVP 179
           NF K+ W Q F     V  +++++++L   GV+        ET   ET++ SS P  ++ 
Sbjct: 298 NFAKSKWRQAFNAAAVVHHMRKLHMNLHSPGVRPEVENRPPETQASETSRPSS-PEITIT 356

Query: 180 TAPALSSVIAPKNSTVTLVPEQIGK 204
            AP L   +A     +T +P Q G+
Sbjct: 357 EAPVLDHSVA--LPALTQLPCQHGR 379


>gi|124248539 axin interactor, dorsalization associated [Homo
           sapiens]
          Length = 306

 Score = 33.1 bits (74), Expect = 0.57
 Identities = 39/183 (21%), Positives = 70/183 (38%), Gaps = 29/183 (15%)

Query: 26  GVQTEDWGQFMHICDIINTTQDGPKDAVKALKKRISKNYNHKEI----QLTLSLIDMCVQ 81
           G   + WGQ +   D             + L+K     +N+ E     + T+  I  C++
Sbjct: 19  GADFDSWGQLVEAIDEYQIL-------ARHLQKEAQAQHNNSEFTEEQKKTIGKIATCLE 71

Query: 82  NCGPSFQSLIVKKEFVKENLVKLLNPRYNLPLDIQNRILNFIKTWSQGFPGGVDVSEVKE 141
               + QS   ++EF  E+L KL              IL  I T+++ FP  V    ++ 
Sbjct: 72  LRSAALQSTQSQEEFKLEDLKKL------------EPILKNILTYNKEFPFDVQPVPLRR 119

Query: 142 VYLDLVKKGVQFPPSEAEAETARQETAQISSN-PPTSVPTAPALSSVIAPKNSTVTLVPE 200
           +     ++ ++F   E E            +  P T +P  P+      P  + +T+  E
Sbjct: 120 ILAPGEEENLEFEEDEEEGGAGAGSPDSFPARVPGTLLPRLPS-----EPGMTLLTIRIE 174

Query: 201 QIG 203
           +IG
Sbjct: 175 KIG 177


>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
           sapiens]
          Length = 805

 Score = 33.1 bits (74), Expect = 0.57
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 13/102 (12%)

Query: 361 LHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQS 420
           LH  M +L LE+ EI    ++ S  L   + +++  +          S  T+   P + +
Sbjct: 204 LHDSMEMLRLEDKEIN---KKRSSTLDCKYKFESCSKEDFRA-----SSSTLRRQPVDMT 255

Query: 421 LPPLPSNHPAMTKSD-LQPPNY----YEVMEFDPLAPAVTTE 457
              LP + P MT S+  +PP Y     + +   P+ P+V T+
Sbjct: 256 YSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQ 297


>gi|109715849 chromosome 6 open reading frame 204 isoform b [Homo
           sapiens]
          Length = 496

 Score = 33.1 bits (74), Expect = 0.57
 Identities = 26/102 (25%), Positives = 46/102 (45%), Gaps = 13/102 (12%)

Query: 361 LHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVSLQTIAAAPSNQS 420
           LH  M +L LE+ EI    ++ S  L   + +++  +          S  T+   P + +
Sbjct: 204 LHDSMEMLRLEDKEIN---KKRSSTLDCKYKFESCSKEDFRA-----SSSTLRRQPVDMT 255

Query: 421 LPPLPSNHPAMTKSD-LQPPNY----YEVMEFDPLAPAVTTE 457
              LP + P MT S+  +PP Y     + +   P+ P+V T+
Sbjct: 256 YSALPESKPIMTSSEAFEPPKYLMLGQQAVGGVPIQPSVRTQ 297


>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 349 PSSDVTNNLKPSLHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVS 408
           P   V    +P    Q+    L   +  P AQ  SQ L+   AY+     S+S+ L  +S
Sbjct: 354 PQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLS---AYN-----SSSLSLNSLS 405

Query: 409 LQTIAAAPSNQSLPPLPSNHPAMTKSDLQPPNYYEVMEFDP 449
               +     Q  PP  S+HP+ +   L  PN+  +  F P
Sbjct: 406 SSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTP 446


>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
           sapiens]
          Length = 1259

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 28/101 (27%), Positives = 42/101 (41%), Gaps = 8/101 (7%)

Query: 349 PSSDVTNNLKPSLHPQMNLLALENTEIPPFAQRTSQNLTSSHAYDNFLEHSNSVFLQPVS 408
           P   V    +P    Q+    L   +  P AQ  SQ L+   AY+     S+S+ L  +S
Sbjct: 354 PQPQVQRPPRPQSPTQLLHQNLPPVQAHPSAQSLSQPLS---AYN-----SSSLSLNSLS 405

Query: 409 LQTIAAAPSNQSLPPLPSNHPAMTKSDLQPPNYYEVMEFDP 449
               +     Q  PP  S+HP+ +   L  PN+  +  F P
Sbjct: 406 SSRSSTPAKTQPAPPHISHHPSASPFPLSLPNHSPLHSFTP 446


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 32.3 bits (72), Expect = 0.97
 Identities = 42/188 (22%), Positives = 77/188 (40%), Gaps = 26/188 (13%)

Query: 234 EDIELLQKLYKTGREMQERIMDLLVVV-------ENEDVTVELIQVNEDLNNAILGYERF 286
           ED+ L + + + G  + ER +DLL +        +NE ++ ELI+   DL  +     +F
Sbjct: 575 EDLNLTENISQ-GDRISERKLDLLSLKNMSEAQSKNEFLSRELIEKERDLERSRTVIAKF 633

Query: 287 TRNQQRILEQNKNQKEATNTTSEPSAPSQDLLDLSPSPRMPRATLGELNTMNNQLSGLNF 346
               + ++E+NK  +E            + L  +    + P    GE + +   L  L  
Sbjct: 634 QNKLKELVEENKQLEEGM---------KEILQAIKEMQKDPDVKGGETSLIIPSLERLVN 684

Query: 347 SLPSSDVTNNLKPSLH--PQMNLLALENTEIPPFAQRT-------SQNLTSSHAYDNFLE 397
           ++ S +       SLH   Q++ L   N E+    + +       SQ L  ++   + LE
Sbjct: 685 AIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLE 744

Query: 398 HSNSVFLQ 405
              S+  Q
Sbjct: 745 KETSLLRQ 752


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.129    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,655,419
Number of Sequences: 37866
Number of extensions: 857709
Number of successful extensions: 3332
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 3234
Number of HSP's gapped (non-prelim): 170
length of query: 476
length of database: 18,247,518
effective HSP length: 106
effective length of query: 370
effective length of database: 14,233,722
effective search space: 5266477140
effective search space used: 5266477140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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