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Search of human proteins with 190014612
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|190014612 transmembrane and coiled-coil domain family 1
isoform c [Homo sapiens]
(539 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|190014612 transmembrane and coiled-coil domain family 1 isofo... 1039 0.0
gi|190014610 transmembrane and coiled-coil domain family 1 isofo... 1039 0.0
gi|39930343 transmembrane and coiled-coil domain family 1 isofor... 637 0.0
gi|54792740 transmembrane and coiled-coil domain family 2 [Homo ... 588 e-168
gi|188497714 transmembrane and coiled-coil domain family 3 [Homo... 427 e-119
gi|4503177 testis expressed 28 [Homo sapiens] 135 1e-31
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 47 3e-05
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 46 8e-05
gi|42794779 myosin 18A isoform b [Homo sapiens] 46 8e-05
gi|28416946 myosin 18A isoform a [Homo sapiens] 46 8e-05
gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo sapi... 46 1e-04
gi|53729363 leucine rich repeat and sterile alpha motif containi... 46 1e-04
gi|53729361 leucine rich repeat and sterile alpha motif containi... 46 1e-04
gi|53729359 leucine rich repeat and sterile alpha motif containi... 46 1e-04
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 45 2e-04
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 45 2e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 44 3e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 44 3e-04
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 44 3e-04
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 44 3e-04
gi|219555718 synaptonemal complex central element protein 1 isof... 44 4e-04
gi|219555716 synaptonemal complex central element protein 1 isof... 44 4e-04
gi|154354987 hook homolog 2 isoform 2 [Homo sapiens] 44 4e-04
gi|154354985 hook homolog 2 isoform 1 [Homo sapiens] 44 4e-04
gi|221139761 zinc finger protein 853 [Homo sapiens] 44 5e-04
gi|156071420 hypothetical protein LOC728912 [Homo sapiens] 44 5e-04
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho... 44 5e-04
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 43 6e-04
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 43 8e-04
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 43 8e-04
>gi|190014612 transmembrane and coiled-coil domain family 1 isoform
c [Homo sapiens]
Length = 539
Score = 1039 bits (2687), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 1 MKRGTSLHSRRGKPEAPKGSPQINRKSGQEMTAVMQSGRPRSSSTTDAPTSSAMMEIACA 60
MKRGTSLHSRRGKPEAPKGSPQINRKSGQEMTAVMQSGRPRSSSTTDAPTSSAMMEIACA
Sbjct: 1 MKRGTSLHSRRGKPEAPKGSPQINRKSGQEMTAVMQSGRPRSSSTTDAPTSSAMMEIACA 60
Query: 61 AAAAAAACLPGEEGTAERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAI 120
AAAAAAACLPGEEGTAERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAI
Sbjct: 61 AAAAAAACLPGEEGTAERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAI 120
Query: 121 AHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQ 180
AHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQ
Sbjct: 121 AHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQ 180
Query: 181 LQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSF 240
LQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSF
Sbjct: 181 LQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSF 240
Query: 241 SQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSS 300
SQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSS
Sbjct: 241 SQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSS 300
Query: 301 PKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQA 360
PKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQA
Sbjct: 301 PKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQA 360
Query: 361 RLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASME 420
RLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASME
Sbjct: 361 RLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASME 420
Query: 421 EKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILL 480
EKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILL
Sbjct: 421 EKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILL 480
Query: 481 AVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVERFFSSPR 539
AVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVERFFSSPR
Sbjct: 481 AVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVERFFSSPR 539
>gi|190014610 transmembrane and coiled-coil domain family 1 isoform
a [Homo sapiens]
Length = 653
Score = 1039 bits (2687), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 1 MKRGTSLHSRRGKPEAPKGSPQINRKSGQEMTAVMQSGRPRSSSTTDAPTSSAMMEIACA 60
MKRGTSLHSRRGKPEAPKGSPQINRKSGQEMTAVMQSGRPRSSSTTDAPTSSAMMEIACA
Sbjct: 115 MKRGTSLHSRRGKPEAPKGSPQINRKSGQEMTAVMQSGRPRSSSTTDAPTSSAMMEIACA 174
Query: 61 AAAAAAACLPGEEGTAERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAI 120
AAAAAAACLPGEEGTAERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAI
Sbjct: 175 AAAAAAACLPGEEGTAERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAI 234
Query: 121 AHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQ 180
AHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQ
Sbjct: 235 AHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQ 294
Query: 181 LQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSF 240
LQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSF
Sbjct: 295 LQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSF 354
Query: 241 SQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSS 300
SQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSS
Sbjct: 355 SQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSS 414
Query: 301 PKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQA 360
PKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQA
Sbjct: 415 PKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQA 474
Query: 361 RLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASME 420
RLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASME
Sbjct: 475 RLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASME 534
Query: 421 EKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILL 480
EKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILL
Sbjct: 535 EKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILL 594
Query: 481 AVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVERFFSSPR 539
AVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVERFFSSPR
Sbjct: 595 AVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVERFFSSPR 653
>gi|39930343 transmembrane and coiled-coil domain family 1 isoform b
[Homo sapiens]
Length = 329
Score = 637 bits (1643), Expect = 0.0
Identities = 329/329 (100%), Positives = 329/329 (100%)
Query: 211 MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD 270
MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD
Sbjct: 1 MHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSAD 60
Query: 271 NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA 330
NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA
Sbjct: 61 NIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA 120
Query: 331 SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR 390
SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR
Sbjct: 121 SSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR 180
Query: 391 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 450
CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL
Sbjct: 181 CERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 240
Query: 451 QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 510
QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST
Sbjct: 241 QQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFST 300
Query: 511 LFLVVFIAFLWKHWDALFSYVERFFSSPR 539
LFLVVFIAFLWKHWDALFSYVERFFSSPR
Sbjct: 301 LFLVVFIAFLWKHWDALFSYVERFFSSPR 329
>gi|54792740 transmembrane and coiled-coil domain family 2 [Homo
sapiens]
Length = 709
Score = 588 bits (1515), Expect = e-168
Identities = 331/555 (59%), Positives = 395/555 (71%), Gaps = 35/555 (6%)
Query: 1 MKRGTSLHSRRG--------------KPEAPKGSPQINRKSGQE--MTAVMQSG--RPRS 42
+KRG SLHS G E +GSP + RK+ Q+ + A++ RPRS
Sbjct: 161 IKRGASLHSSSGGGSSGSSSRRTKSSSLEPQRGSPHLLRKAPQDSSLAAILHQHQCRPRS 220
Query: 43 SSTTDAPTSSAMMEIACAAAAAAAACLPGEEGTAERIERLEVSSLAQTSSAVASSTDGSI 102
SSTTD A A A EG +++++ ++ +L+ + TDG I
Sbjct: 221 SSTTDTALLLADGSNVYLLAEEA-------EGIGDKVDKGDLVALSLPAGH--GDTDGPI 271
Query: 103 HTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAAR 162
D DG PDPQRTKAAI HL QKILK+TEQIKI Q ARDDNVAEYLKLAN+ADKQQ +R
Sbjct: 272 SLDVPDGAPDPQRTKAAIDHLHQKILKITEQIKIEQEARDDNVAEYLKLANNADKQQVSR 331
Query: 163 IKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKV 222
IKQVFEKKNQKSAQTI QL KKLEHY R+L+E+EQNG RQPKDV RDM QGLKDVGA V
Sbjct: 332 IKQVFEKKNQKSAQTIAQLHKKLEHYRRRLKEIEQNGPSRQPKDVLRDMQQGLKDVGANV 391
Query: 223 ----TGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDS 278
+GF GVV+ VKG S SQATH+A VVSKPRE ASLIRNKFGSADNI +LKD
Sbjct: 392 RAGISGFGGGVVEGVKGSLSGLSQATHTA---VVSKPREFASLIRNKFGSADNIAHLKDP 448
Query: 279 LEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGA-SSSKTNT 337
LE+G ++A +AL + SSPKYGS+++CSSA++ S GA S +G GA S K+N
Sbjct: 449 LEDGPPEEAARALSGSATLVSSPKYGSDDECSSASASSAGAGSNSGAGPGGALGSPKSNA 508
Query: 338 LDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQ 397
L DALL E++EI+E Q+ LE+S E LK QRDY+ + Q LQEERYR ERLEEQ
Sbjct: 509 LYGAPGNLDALLEELREIKEGQSHLEDSMEDLKTQLQRDYTYMTQCLQEERYRYERLEEQ 568
Query: 398 LNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQV 457
LNDLTELHQNE+ NLKQELASMEEK+AYQSYERARDIQEA+E+C TR++K+ELQQQQQQV
Sbjct: 569 LNDLTELHQNEMTNLKQELASMEEKVAYQSYERARDIQEAVESCLTRVTKLELQQQQQQV 628
Query: 458 VQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFI 517
VQLEG+ENA AR LLGK IN++LA+MAVLLVFVST+AN + PLMKTR R ST LV+ +
Sbjct: 629 VQLEGVENANARALLGKFINVILALMAVLLVFVSTIANFITPLMKTRLRITSTTLLVLVL 688
Query: 518 AFLWKHWDALFSYVE 532
LWKHWD+L +E
Sbjct: 689 FLLWKHWDSLTYLLE 703
>gi|188497714 transmembrane and coiled-coil domain family 3 [Homo
sapiens]
Length = 477
Score = 427 bits (1098), Expect = e-119
Identities = 239/460 (51%), Positives = 314/460 (68%), Gaps = 17/460 (3%)
Query: 78 RIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIA 137
R+ER ++++L+ + +D +++ D DG D + K L+QKILK+TEQIKI
Sbjct: 26 RVERHDMNTLSLPLNIRRGGSDTNLNFDVPDGILDFHKVKLTADSLKQKILKVTEQIKIE 85
Query: 138 QTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQ 197
QT+RD NVAEYLKL N+ADKQQA RIKQVFEKKNQKSA +I QLQKKLE YHRKLRE+EQ
Sbjct: 86 QTSRDGNVAEYLKLVNNADKQQAGRIKQVFEKKNQKSAHSIAQLQKKLEQYHRKLREIEQ 145
Query: 198 NGIPRQPKDV----FRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVS 253
NG R KD+ +D+H+ LKD K + + ++S K G S + V +
Sbjct: 146 NGASRSSKDISKDHLKDIHRSLKDAHVK-SRTAPHCMESSKSGMPGVSL---TPPVFVFN 201
Query: 254 KPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSAT 313
K RE A+LIRNKFGSADNI +LK+SLEE + + + +A G + + PKYGS+++CSS T
Sbjct: 202 KSREFANLIRNKFGSADNIAHLKNSLEEFRPEASARAYGGSATIVNKPKYGSDDECSSGT 261
Query: 314 SGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHY 373
SGS +N A GAS TLD Q +L E++EI++TQA+L E E LK +
Sbjct: 262 SGSADSNGNQSFGAGGAS-----TLDSQGK-LAVILEELREIKDTQAQLAEDIEALKVQF 315
Query: 374 QRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARD 433
+R+Y I QTLQEERYR ERLE+QL+DLT+LHQ+E NLKQELAS+EEK+AYQ+YER+RD
Sbjct: 316 KREYGFISQTLQEERYRYERLEDQLHDLTDLHQHETANLKQELASIEEKVAYQAYERSRD 375
Query: 434 IQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTV 493
IQEALE+CQTRISK+EL QQ+QQ +Q + A+ LLG+ IN++LA M V+LV VST+
Sbjct: 376 IQEALESCQTRISKLELHQQEQQALQ---TDTVNAKVLLGRCINVILAFMTVILVCVSTI 432
Query: 494 ANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVER 533
A V P+MK+R T F V +A K+WD + +ER
Sbjct: 433 AKFVSPMMKSRCHILGTFFAVTLLAIFCKNWDHILCAIER 472
>gi|4503177 testis expressed 28 [Homo sapiens]
Length = 410
Score = 135 bits (339), Expect = 1e-31
Identities = 127/432 (29%), Positives = 197/432 (45%), Gaps = 82/432 (18%)
Query: 104 TDSVDGTPDPQR-TKAAIAH-----LQQKILKLTEQIKIAQTARDDNVAEYLKLANSADK 157
+ S DG P +AH ++ +IL L+EQ+++ + +RD N YLKL + AD+
Sbjct: 26 SSSEDGPSGPSSLADGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVSKADR 85
Query: 158 QQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKD 217
Q I+Q FEK NQ+++ TI Q++ +L H++L+E+E+ P
Sbjct: 86 HQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEGCRP---------------- 129
Query: 218 VGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKD 277
EG++ + S + + A++S+P E G D NL
Sbjct: 130 ---------EGLLLMAE---SDPANCEPPSEKALLSEPPEP--------GGEDGPVNL-- 167
Query: 278 SLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNT 337
A + + S FQS + C + N + +K
Sbjct: 168 -------PHASRPFILESRFQSL----QQGTCLETEDVAQQQNLLLQKVKAELEEAKRFH 216
Query: 338 LDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQ 397
+ +Q S H ++E T +L E+L+E R Q L EE+ RL+ Q
Sbjct: 217 ISLQES-----YHSLKERSLTDLQL--LLESLQEEKCR------QALMEEQVN-GRLQGQ 262
Query: 398 LNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQV 457
L NEI NLK LA EE++AY SYERA++I E E ++RISK+E+ QQV
Sbjct: 263 L--------NEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEM---LQQV 311
Query: 458 VQLEGLENATAR--NLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVV 515
QLE E+ +R +L K ++ L++ VLLVFVST+ C L+ +R T + L L+
Sbjct: 312 TQLEAAEHLQSRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIG 371
Query: 516 FIAFLWKHWDAL 527
W+ W A+
Sbjct: 372 LGVLAWQRWRAI 383
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 47.4 bits (111), Expect = 3e-05
Identities = 35/134 (26%), Positives = 61/134 (45%), Gaps = 19/134 (14%)
Query: 347 ALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCER------------- 393
A E+++ T + EE+ LK I +T +EER ++
Sbjct: 411 AAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM 470
Query: 394 ---LEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 450
EEQ+ L +LH+ E+ +QEL +K+ + E ++ ALE Q+ K+
Sbjct: 471 KKSSEEQIAKLQKLHEKELARKEQELT---KKLQTREREFQEQMKVALEKSQSEYLKISQ 527
Query: 451 QQQQQQVVQLEGLE 464
+++QQ+ + LE LE
Sbjct: 528 EKEQQESLALEELE 541
Score = 47.4 bits (111), Expect = 3e-05
Identities = 89/436 (20%), Positives = 168/436 (38%), Gaps = 70/436 (16%)
Query: 75 TAERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQI 134
T E+ E SL Q S V D + + + Q K H ++ K E
Sbjct: 443 TIEKTSEEERISLQQELSRVKQEV-----VDVMKKSSEEQIAKLQKLHEKELARKEQELT 497
Query: 135 KIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKS-AQTILQLQKKLEHYHRKLR 193
K QT R+ E +K+A +K Q+ +K EK+ Q+S A L+LQKK
Sbjct: 498 KKLQT-REREFQEQMKVA--LEKSQSEYLKISQEKEQQESLALEELELQKK--------- 545
Query: 194 EVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVS 253
I + ++ RD+ Q + ++ + S++ +
Sbjct: 546 -----AILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNK 600
Query: 254 KPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSAT 313
+EI ++ +++ + +D+L + L V+ + E C
Sbjct: 601 HNKEITVMVEKHKTELESLKHQQDALWT-------EKLQVLKQQYQTEMEKLREKCEQEK 653
Query: 314 SGSVGANSTTGGIAVGASSSKT-NTLDMQSSGFDALLHEIQEIRETQARLEESFETLKE- 371
+ + + KT LD++ + ++L E+ E+ + + +LEE LK+
Sbjct: 654 ETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQ 713
Query: 372 -----------------HYQRDYSLIMQTLQEERYRCER-LEEQLNDLTEL--------- 404
H+Q+ I++ + R E+ L++Q+N L L
Sbjct: 714 TDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLK 773
Query: 405 -HQNEILNLKQELASMEEKIAYQSYERARDIQEALEAC---QTRISKMELQQQQQQVVQL 460
HQ + NL+ ++ E ++ Q D+ ++ ++ QT+ + +L Q QQ+++ L
Sbjct: 774 EHQAHVENLEADIKRSEGEL--QQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDL 831
Query: 461 EGLENATARNLLGKLI 476
E T R LL K +
Sbjct: 832 E-----TERILLTKQV 842
Score = 42.4 bits (98), Expect = 0.001
Identities = 75/359 (20%), Positives = 147/359 (40%), Gaps = 69/359 (19%)
Query: 114 QRTKA---AIAHLQQKILKL-TEQIKIA-QTARDDNVAEYLKLANSADKQQAARIKQVFE 168
++TKA +A LQQK+L L TE+I + Q A + + + A K Q + Q E
Sbjct: 812 EQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLE 871
Query: 169 KKNQKSAQTILQL----QKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLK---DVGAK 221
K+N + Q + L + KLE +++ + +Q I + +++ M +G K ++ +
Sbjct: 872 KQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQ--ILVEKENMILQMREGQKKEIEILTQ 929
Query: 222 VTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEE 281
E + + + + + V K +E+ ++ K D LK LE
Sbjct: 930 KLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKL--LDQEAKLKKELEN 987
Query: 282 GQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQ 341
++ + K E+ ++ ANS GI+ S +TN
Sbjct: 988 TALELSQK----------------EKQFNAKMLEMAQANSA--GISDAVSRLETNQ---- 1025
Query: 342 SSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDL 401
+E E+L E ++R+ + ++ ++ +L +Q +L
Sbjct: 1026 ---------------------KEQIESLTEVHRRELNDVISIWEK------KLNQQAEEL 1058
Query: 402 TELHQNEILNLKQELASMEEKIAYQSYERARDIQEAL----EACQTRISKMELQQQQQQ 456
E+H+ ++ +QE+A +++KI E+ +E E + + ELQ+Q +Q
Sbjct: 1059 QEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQ 1117
Score = 38.5 bits (88), Expect = 0.016
Identities = 49/226 (21%), Positives = 90/226 (39%), Gaps = 20/226 (8%)
Query: 254 KPREIASL---IRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCS 310
K EIA L I+ + + K+ E ++ KAL + + + E
Sbjct: 380 KEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDE 439
Query: 311 SATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQ-ARLEESFETL 369
+ + + S K +D+ + + ++Q++ E + AR E+
Sbjct: 440 QIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKK 499
Query: 370 KEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYE 429
+ +R++ M+ E+ E L E Q E L L +EL ++ I +S
Sbjct: 500 LQTREREFQEQMKVALEKSQ-----SEYLKISQEKEQQESLAL-EELELQKKAILTESEN 553
Query: 430 RARDIQEALEACQTRISKME------LQQQQQQ----VVQLEGLEN 465
+ RD+Q+ E +TRI ++E LQ+ + Q V LE +N
Sbjct: 554 KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKN 599
Score = 37.4 bits (85), Expect = 0.035
Identities = 48/206 (23%), Positives = 84/206 (40%), Gaps = 25/206 (12%)
Query: 276 KDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKT 335
K++L+E Q+D+ + L I + + K A + G +
Sbjct: 316 KEALQE-QLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMH 374
Query: 336 NTLDMQSSGFDALLHEIQEI----RETQARLEESFETLKEHYQRDYSLIMQTLQEERYRC 391
TL+M+ L I+++ E + + E+S E ++ S +T + R
Sbjct: 375 ETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLK 434
Query: 392 ERLEEQLNDLTELHQNEILNLKQELA------------SMEEKIA----YQSYERARDIQ 435
++EQ+ + + + E ++L+QEL+ S EE+IA E AR Q
Sbjct: 435 AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQ 494
Query: 436 EALEACQTRISKMELQQQQQQVVQLE 461
E + QTR E + Q+Q V LE
Sbjct: 495 ELTKKLQTR----EREFQEQMKVALE 516
Score = 37.0 bits (84), Expect = 0.046
Identities = 27/125 (21%), Positives = 61/125 (48%), Gaps = 9/125 (7%)
Query: 336 NTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLE 395
N L+ + +G + E Q++ + RL++ L++ +Q++ ++ + +ER E+++
Sbjct: 1926 NDLEFKLAGAE---REKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQERE--EKIK 1980
Query: 396 EQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQ 455
++ DL H + LKQ + ++A + E I+E + Q + L+ Q+
Sbjct: 1981 QEQEDLELKHNS---TLKQLMREFNTQLAQKEQELEMTIKETINKAQ-EVEAELLESHQE 2036
Query: 456 QVVQL 460
+ QL
Sbjct: 2037 ETNQL 2041
Score = 33.1 bits (74), Expect = 0.66
Identities = 25/87 (28%), Positives = 44/87 (50%), Gaps = 4/87 (4%)
Query: 370 KEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE--LHQNEILNLK-QELASMEEKI-AY 425
K++ + + + +TLQE+ C+ LE+++ +L + Q E+ ++ +EL S EK+ A
Sbjct: 1828 KQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQAL 1887
Query: 426 QSYERARDIQEALEACQTRISKMELQQ 452
Q + E LE SK L Q
Sbjct: 1888 QQMDGRNKPTELLEENTEEKSKSHLVQ 1914
Score = 32.3 bits (72), Expect = 1.1
Identities = 22/119 (18%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
Query: 338 LDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQ 397
LD Q+ FD L E+++ + + E + ET + + + ++ E L E
Sbjct: 1488 LDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEV 1547
Query: 398 LNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQ 456
L + + E L Q+L +E + + R ++ +E + + ++ M+ + + ++
Sbjct: 1548 LKNYNQQKDIEHKELVQKLQHFQE-LGEEKDNRVKEAEEKILTLENQVYSMKAELETKK 1605
Score = 30.4 bits (67), Expect = 4.3
Identities = 65/386 (16%), Positives = 150/386 (38%), Gaps = 46/386 (11%)
Query: 121 AHLQQKILKLTEQIKIAQTARDD---NVAEYLKLANSAD------KQQAARIKQVFEKK- 170
AH+++ K E++ + QT + ++E LK + + K Q ++KQ E K
Sbjct: 666 AHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM 725
Query: 171 -------NQKSAQTILQLQKKLEHYHRKLRE-VEQNGIPRQPKDVFRDMHQG-LKDVGAK 221
Q+ I + + ++ + L++ + Q + + +D HQ ++++ A
Sbjct: 726 DEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEAD 785
Query: 222 VTGFSEGVVDSVKGG---FSSFSQATHSAAGA----VVSKPREIASLIRNKFGSADNIPN 274
+ SEG + F S+ ATH A + +++ L + +
Sbjct: 786 IKR-SEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAE 844
Query: 275 LKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSK 334
++ ++ + + V Q K SE + + V + G +
Sbjct: 845 VEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDG---NKEQEQ 901
Query: 335 TNTLDMQSSGF-----DALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERY 389
T + ++ + EI+ + + + E+S L E Y+ + + +
Sbjct: 902 TKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKF-------KNQEK 954
Query: 390 RCERLEEQLNDLTELHQNEILN----LKQELASMEEKIAYQSYERARDIQEALEACQTRI 445
+ E+++++ ++ E + ++L+ LK+EL + +++ + + + E +A I
Sbjct: 955 KMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGI 1014
Query: 446 SKMELQQQQQQVVQLEGLENATARNL 471
S + + Q Q+E L R L
Sbjct: 1015 SDAVSRLETNQKEQIESLTEVHRREL 1040
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 46.2 bits (108), Expect = 8e-05
Identities = 81/438 (18%), Positives = 171/438 (39%), Gaps = 53/438 (12%)
Query: 80 ERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQT 139
E +V+SL +T S + + D ++ K L++ KL +K+AQ
Sbjct: 1014 EEDKVNSLNKTKSKLEQQVE--------DLESSLEQEKKLRVDLERNKRKLEGDLKLAQE 1065
Query: 140 ARDDNVAEYLKLANSADKQQAARIKQVFE----KKNQKSAQTI-LQLQKKLEHYHRKLRE 194
+ L L N + K+ FE + + QT+ LQ QKK++ ++ E
Sbjct: 1066 S-------ILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEE 1118
Query: 195 VEQN---------GIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATH 245
+E+ +Q D R++ + L + + G + ++ K + F +
Sbjct: 1119 LEEEIEAERATRAKTEKQRSDYARELEE-LSERLEEAGGVTSTQIELNKKREAEFLKLRR 1177
Query: 246 SAAGAVVSKPREIASLIRNKFGSA-------DNIPNLKDSLEEG------QVDDAGKALG 292
A + +A+L + S DN+ +K LE+ ++DD ++
Sbjct: 1178 DLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSME 1237
Query: 293 VISNFQSSPK---YGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNT--LDMQSSGFDA 347
+S +++ + E+ S A + + + S +T L Q ++
Sbjct: 1238 SVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKES 1297
Query: 348 LLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELH-- 405
++ ++ ++ + E + E + + + LQ R+ C+ L EQ + E
Sbjct: 1298 IVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAE 1357
Query: 406 -QNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLE 464
Q + E+A K + +R +++EA + R+ E +Q + + LE
Sbjct: 1358 LQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSE-EQVEAVNAKCASLE 1416
Query: 465 NATARNLLGKLINILLAV 482
T + L G++ ++++ V
Sbjct: 1417 K-TKQRLQGEVEDLMVDV 1433
Score = 38.9 bits (89), Expect = 0.012
Identities = 40/138 (28%), Positives = 63/138 (45%), Gaps = 26/138 (18%)
Query: 326 IAVGASSSKTNTLDMQSSGFDALLHEIQ-EIRETQARLEESFETLKEHYQRDYSLIMQTL 384
+ V ++S LD + FD +L E + + E+QA LE S LKE ++L
Sbjct: 1431 VDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEAS---LKES---------RSL 1478
Query: 385 QEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIA-----YQSYERAR------- 432
E ++ + E+ D E + E NL+QE+A + E+IA E++R
Sbjct: 1479 STELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEK 1538
Query: 433 -DIQEALEACQTRISKME 449
DIQ ALE + + E
Sbjct: 1539 ADIQLALEEAEAALEHEE 1556
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 46.2 bits (108), Expect = 8e-05
Identities = 38/144 (26%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 339 DMQSSGFD----ALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERL 394
DM +GF +L E+Q+I +++ E S +K+ RD ++ +EE L
Sbjct: 1506 DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL-RDLEAKVKDQEEE------L 1558
Query: 395 EEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQ 454
+EQ + L Q + L L+ E+ M + + + R +++EA ++CQ ++ +ME+Q ++
Sbjct: 1559 DEQAGTIQMLEQAK-LRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
Query: 455 QQVVQLEGLENATARNLLGKLINI 478
+ + + L R L GKL +
Sbjct: 1618 EYEDKQKVLRE--KRELEGKLATL 1639
Score = 39.3 bits (90), Expect = 0.009
Identities = 62/300 (20%), Positives = 123/300 (41%), Gaps = 28/300 (9%)
Query: 162 RIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAK 221
R++Q FE K + Q QL+++L E ++ +Q K + + L+D
Sbjct: 1388 RLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR--ALQQLKKKCQRLTAELQDTKLH 1445
Query: 222 VTG--FSEGVVDSVKGGFSS-FSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDS 278
+ G ++ + F S SQA A + + + L R K +LK
Sbjct: 1446 LEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREK----LQREKDMLLAEAFSLKQQ 1501
Query: 279 LEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTL 338
LEE +D AG V+S S+E A+ V V + L
Sbjct: 1502 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKV---KDQEEEL 1558
Query: 339 DMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCER----- 393
D Q+ IQ + + + RLE E +++ + ++ + ++E R C++
Sbjct: 1559 DEQAG-------TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM 1611
Query: 394 ---LEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 450
LEE+ D ++ E L+ +LA++ +++ + +E + +++ L+ + ++ +L
Sbjct: 1612 EVQLEEEYEDKQKV-LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQL 1670
Score = 32.0 bits (71), Expect = 1.5
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 34/143 (23%)
Query: 352 IQEIRETQARLEESFETLKE--------------HYQRDYSLIMQTLQEERYRCERLEEQ 397
++E+ T+ RL++ FE E Q D + LQ+ + +C+RL +
Sbjct: 1379 VREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAE 1438
Query: 398 LNDLTELH------QNEILNLKQ-----ELA-----SMEEKIAYQSYERARD--IQEALE 439
L D T+LH +N L KQ EL+ + EK+ + +R +D + EA
Sbjct: 1439 LQD-TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
Query: 440 ACQTRISK-MELQQQQQQVVQLE 461
Q K M++ Q+VV LE
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLE 1520
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 46.2 bits (108), Expect = 8e-05
Identities = 38/144 (26%), Positives = 73/144 (50%), Gaps = 14/144 (9%)
Query: 339 DMQSSGFD----ALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERL 394
DM +GF +L E+Q+I +++ E S +K+ RD ++ +EE L
Sbjct: 1506 DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL-RDLEAKVKDQEEE------L 1558
Query: 395 EEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQ 454
+EQ + L Q + L L+ E+ M + + + R +++EA ++CQ ++ +ME+Q ++
Sbjct: 1559 DEQAGTIQMLEQAK-LRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
Query: 455 QQVVQLEGLENATARNLLGKLINI 478
+ + + L R L GKL +
Sbjct: 1618 EYEDKQKVLRE--KRELEGKLATL 1639
Score = 39.3 bits (90), Expect = 0.009
Identities = 62/300 (20%), Positives = 123/300 (41%), Gaps = 28/300 (9%)
Query: 162 RIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAK 221
R++Q FE K + Q QL+++L E ++ +Q K + + L+D
Sbjct: 1388 RLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR--ALQQLKKKCQRLTAELQDTKLH 1445
Query: 222 VTG--FSEGVVDSVKGGFSS-FSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDS 278
+ G ++ + F S SQA A + + + L R K +LK
Sbjct: 1446 LEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREK----LQREKDMLLAEAFSLKQQ 1501
Query: 279 LEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTL 338
LEE +D AG V+S S+E A+ V V + L
Sbjct: 1502 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKV---KDQEEEL 1558
Query: 339 DMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCER----- 393
D Q+ IQ + + + RLE E +++ + ++ + ++E R C++
Sbjct: 1559 DEQAG-------TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM 1611
Query: 394 ---LEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 450
LEE+ D ++ E L+ +LA++ +++ + +E + +++ L+ + ++ +L
Sbjct: 1612 EVQLEEEYEDKQKV-LREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQL 1670
Score = 32.0 bits (71), Expect = 1.5
Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 34/143 (23%)
Query: 352 IQEIRETQARLEESFETLKE--------------HYQRDYSLIMQTLQEERYRCERLEEQ 397
++E+ T+ RL++ FE E Q D + LQ+ + +C+RL +
Sbjct: 1379 VREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAE 1438
Query: 398 LNDLTELH------QNEILNLKQ-----ELA-----SMEEKIAYQSYERARD--IQEALE 439
L D T+LH +N L KQ EL+ + EK+ + +R +D + EA
Sbjct: 1439 LQD-TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
Query: 440 ACQTRISK-MELQQQQQQVVQLE 461
Q K M++ Q+VV LE
Sbjct: 1498 LKQQLEEKDMDIAGFTQKVVSLE 1520
>gi|194097392 Golgi autoantigen, golgin subfamily a, 2 [Homo
sapiens]
Length = 1002
Score = 45.8 bits (107), Expect = 1e-04
Identities = 60/276 (21%), Positives = 106/276 (38%), Gaps = 33/276 (11%)
Query: 182 QKKLEHYHRKLREVEQNGIPRQPKDVFRDMH-QGLKDVGAKVTGFSEGVVDSVKGGFSSF 240
Q KL +KLRE +Q P P + + + +G D+ K ++
Sbjct: 19 QSKLAAAKKKLREYQQRNSPGVPTGAKKKKKIKNGSNPETTTSGGCHSPEDTPKDNAATL 78
Query: 241 SQATHSAA-GAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQS 299
+ + G V S + S+ ++ ADN+PNL D + F S
Sbjct: 79 QPSDDTVLPGGVPSPGASLTSMAASQNHDADNVPNLMDETK---------------TFSS 123
Query: 300 SPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQ 359
+ S S +G V ++T ASS+ L+ S + L + T
Sbjct: 124 TE---SLRQLSQQLNGLVCESATCVNGEGPASSANLKDLE---SRYQQLAVALDSSYVTN 177
Query: 360 ARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASM 419
+L + E LK+ Q I L+EE+ C + + L + ++H I L E A +
Sbjct: 178 KQLNITIEKLKQQNQE----ITDQLEEEKKECHQKQGALREQLQVHIQTIGILVSEKAEL 233
Query: 420 EEKIAY------QSYERARDIQEALEACQTRISKME 449
+ +A+ Q + D+ L+ + R+ ++E
Sbjct: 234 QTALAHTQHAARQKEGESEDLASRLQYSRRRVGELE 269
>gi|53729363 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 45.8 bits (107), Expect = 1e-04
Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 15/137 (10%)
Query: 335 TNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTL-QEERYRCER 393
T L SS D +L Q ++E Q+RLE+ + H + + + L Q E+ R
Sbjct: 282 TQLLQQSSSQKDEIL---QTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSR 338
Query: 394 LEEQLND-LTELHQNEIL-NLKQELASMEEKIAYQSYE----RARDIQEAL-----EACQ 442
+++ L D + +EIL +L+ E ME+ ++ E R RD+ A+ E+C+
Sbjct: 339 IQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCK 398
Query: 443 TRISKMELQQQQQQVVQ 459
R+ +M + Q+Q +VQ
Sbjct: 399 NRLIQMAYESQRQNLVQ 415
>gi|53729361 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 45.8 bits (107), Expect = 1e-04
Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 15/137 (10%)
Query: 335 TNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTL-QEERYRCER 393
T L SS D +L Q ++E Q+RLE+ + H + + + L Q E+ R
Sbjct: 282 TQLLQQSSSQKDEIL---QTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSR 338
Query: 394 LEEQLND-LTELHQNEIL-NLKQELASMEEKIAYQSYE----RARDIQEAL-----EACQ 442
+++ L D + +EIL +L+ E ME+ ++ E R RD+ A+ E+C+
Sbjct: 339 IQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCK 398
Query: 443 TRISKMELQQQQQQVVQ 459
R+ +M + Q+Q +VQ
Sbjct: 399 NRLIQMAYESQRQNLVQ 415
>gi|53729359 leucine rich repeat and sterile alpha motif containing
1 [Homo sapiens]
Length = 723
Score = 45.8 bits (107), Expect = 1e-04
Identities = 39/137 (28%), Positives = 68/137 (49%), Gaps = 15/137 (10%)
Query: 335 TNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTL-QEERYRCER 393
T L SS D +L Q ++E Q+RLE+ + H + + + L Q E+ R
Sbjct: 282 TQLLQQSSSQKDEIL---QTVKEEQSRLEQGLSEHQRHLNAERQRLQEQLKQTEQNISSR 338
Query: 394 LEEQLND-LTELHQNEIL-NLKQELASMEEKIAYQSYE----RARDIQEAL-----EACQ 442
+++ L D + +EIL +L+ E ME+ ++ E R RD+ A+ E+C+
Sbjct: 339 IQKLLQDNQRQKKSSEILKSLENERIRMEQLMSITQEETESLRRRDVASAMQQMLTESCK 398
Query: 443 TRISKMELQQQQQQVVQ 459
R+ +M + Q+Q +VQ
Sbjct: 399 NRLIQMAYESQRQNLVQ 415
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 44.7 bits (104), Expect = 2e-04
Identities = 79/413 (19%), Positives = 164/413 (39%), Gaps = 60/413 (14%)
Query: 77 ERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKI 136
E + + S L SS +S G+ H S G + + L Q + +L
Sbjct: 200 EELSHINQSLLQSQSSGDSSDDSGAQHPSS--GEKLKYNQQGEVQQLHQNLHRLQILCNS 257
Query: 137 AQTA----RDDNVAEYLKLANSADKQQAARIKQVFEKKNQK---SAQTILQLQKKLEHYH 189
A+ R N+ LK NS +++ +IK + QK S + L + +H
Sbjct: 258 AENELRYERGQNLD--LKQHNSLLQEENIKIKIELKHAQQKLLDSTKMCSSLTAEYKHCQ 315
Query: 190 RKLREVEQNGIPR-QPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAA 248
+K++E+E + Q ++ + L +KV E ++D + + H
Sbjct: 316 QKIKELELEVLKHTQSIKSQNNLQEKLVQEKSKVADAEEKILDLQRK-----LEHAHKVC 370
Query: 249 --GAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQ---------VDDAGKALGVISNF 297
+S+ +++ I+ + N +K +E Q VD+ + + + +
Sbjct: 371 LTDTCISEKQQLEEKIKE---ATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQVRTLQDK 427
Query: 298 QSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRE 357
++ E CS S + + L+ + +D + QE+ E
Sbjct: 428 ENL----LEMTCSQQQS------------RIQQQEALLKQLENEKRKYDEHVKSNQELSE 471
Query: 358 TQARLEESFETLKEHYQRDYSLI-------MQTLQEERYRCERLEEQLNDLTELHQNEIL 410
++L++ E L+E Y R L+ + +++ + ++++ +L + EL I
Sbjct: 472 KLSKLQQEKEALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTNEVELRDKRIN 531
Query: 411 NLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGL 463
+ E+ ++ KI E+ + IQ+ + A Q +E ++ Q+QV++ E L
Sbjct: 532 QFEDEIGILQHKI-----EKEKAIQDQITA-QNDTLLLEKRKLQEQVIEQEQL 578
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 44.7 bits (104), Expect = 2e-04
Identities = 72/377 (19%), Positives = 145/377 (38%), Gaps = 39/377 (10%)
Query: 105 DSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIK 164
D ++G+ + + K L++ KL +K+AQ + D + +L N K++ +
Sbjct: 1036 DDLEGSLEQE--KKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQL-NEKLKKKEFEMS 1092
Query: 165 QVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQN---------GIPRQPKDVFRDMHQGL 215
+ K + A I QLQKK++ ++ E+E+ +Q D+ R++ + +
Sbjct: 1093 NLQGKIEDEQALAI-QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE-I 1150
Query: 216 KDVGAKVTGFSEGVVDSVKGGFSSF---------SQATHSAAGAVVSKPREIASLIRNKF 266
+ + G + ++ K + F S H A A + K A +
Sbjct: 1151 SERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKH--ADSVAELG 1208
Query: 267 GSADNIPNLKDSLEEGQVDDAGKALGVISNFQ--SSPKYGSEEDCSSATS--GSVGANST 322
D++ +K LE+ + + + + SN + S K E+ C + +
Sbjct: 1209 EQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEE 1268
Query: 323 TGGIAVGASSSKTNTLDMQSSGFDALLHE----IQEIRETQARLEESFETLKEHYQRD-- 376
+ S++ L +S F L E + ++ + + E LK + +
Sbjct: 1269 EQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETK 1328
Query: 377 -YSLIMQTLQEERYRCERLEEQLNDLTELH---QNEILNLKQELASMEEKIAYQSYERAR 432
S + LQ R+ C+ L EQ + E Q + E+A K + +R
Sbjct: 1329 AKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTE 1388
Query: 433 DIQEALEACQTRISKME 449
+++EA + R+ E
Sbjct: 1389 ELEEAKKKLAQRLQDAE 1405
Score = 38.1 bits (87), Expect = 0.021
Identities = 46/163 (28%), Positives = 76/163 (46%), Gaps = 27/163 (16%)
Query: 326 IAVGASSSKTNTLDMQSSGFDALLHEI-QEIRETQARLEESFETLKEHYQRDYSLIMQTL 384
I V S++ LD + FD +L E Q+ ETQA LE S Q++ ++L
Sbjct: 1434 IDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEAS--------QKE----SRSL 1481
Query: 385 QEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTR 444
E ++ + E+ D E + E NL+QE++ + E+IA E + I E LE + +
Sbjct: 1482 STELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIA----EGGKHIHE-LEKVKKQ 1536
Query: 445 I--SKMELQQQQQQVVQLEGLENATARNLLGKLINILLAVMAV 485
+ K ELQ ++ A+ + GK++ I L + V
Sbjct: 1537 LDHEKSELQTSLEEA-------EASLEHEEGKILRIQLELNQV 1572
Score = 29.3 bits (64), Expect = 9.5
Identities = 32/159 (20%), Positives = 69/159 (43%), Gaps = 12/159 (7%)
Query: 77 ERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKI 136
ER ER +A+ AS +HT + ++ + I+ +Q ++ + ++ +
Sbjct: 1697 ERTERGR--KMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARN 1754
Query: 137 AQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVE 196
A+ + + +A K+Q KKN + QT+ LQ +L+ E E
Sbjct: 1755 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME--QTVKDLQLRLD-------EAE 1805
Query: 197 QNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKG 235
Q + K + + + ++++ ++V + V++VKG
Sbjct: 1806 QLALKGGKKQI-QKLEARVRELESEVESEQKHNVEAVKG 1843
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 44.3 bits (103), Expect = 3e-04
Identities = 79/403 (19%), Positives = 160/403 (39%), Gaps = 65/403 (16%)
Query: 98 TDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIA-----QTARDDNVA------ 146
T + DS D + +A IA L+ ++ K E+++ A + A N+A
Sbjct: 1049 TRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRE 1108
Query: 147 ---EYLKLANSADKQQAARIKQVFEKKNQKSAQTILQLQKKLE---------HYHRKLRE 194
+ +L + ++A+R K EK+ + + + L+ +LE R RE
Sbjct: 1109 LESQISELQEDLESERASRNKA--EKQKRDLGEELEALKTELEDTLDSTAAQQELRSKRE 1166
Query: 195 VEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDS------VKGGFSSFSQATHSAA 248
E N + + ++ + ++++ K + E + + VK Q +
Sbjct: 1167 QEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENER 1226
Query: 249 GAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEED 308
G + + E+ L++ K S ++ L+E QV F + +E
Sbjct: 1227 GELAN---EVKVLLQGKGDSEHKRKKVEAQLQELQV-----------KFNEGERVRTEL- 1271
Query: 309 CSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFET 368
T V ++ TG + S SK++ L S ++ L + QE+ + + R + S T
Sbjct: 1272 ADKVTKLQVELDNVTG--LLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLST 1329
Query: 369 LKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKI--AYQ 426
+ + + + + L+EE LE+Q I L ++A M++K+ +
Sbjct: 1330 KLKQVEDEKNSFREQLEEEEEAKHNLEKQ-----------IATLHAQVADMKKKMEDSVG 1378
Query: 427 SYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATAR 469
E A +++ L+ +S Q+ +++V + LE R
Sbjct: 1379 CLETAEEVKRKLQKDLEGLS----QRHEEKVAAYDKLEKTKTR 1417
Score = 32.7 bits (73), Expect = 0.86
Identities = 35/136 (25%), Positives = 66/136 (48%), Gaps = 12/136 (8%)
Query: 338 LDMQSSGFDALLHEIQEIRETQARLEESFET----LKEHYQRDYSLIMQTLQEERYRCER 393
L+ + + F L E +E ++ A+L+ E L+E +R+ Q L++ R + E
Sbjct: 997 LEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQ-RQELEKTRRKLEG 1055
Query: 394 LEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQ 453
L+D Q +I LK +LA EE++ +A + EA Q ++ ++++
Sbjct: 1056 DSTDLSDQIAELQAQIAELKMQLAKKEEEL------QAALARVEEEAAQKNMALKKIREL 1109
Query: 454 QQQVVQL-EGLENATA 468
+ Q+ +L E LE+ A
Sbjct: 1110 ESQISELQEDLESERA 1125
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 44.3 bits (103), Expect = 3e-04
Identities = 71/369 (19%), Positives = 150/369 (40%), Gaps = 52/369 (14%)
Query: 120 IAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARI--KQVFEKKNQKSAQT 177
+ LQ + +LTE+ A E+L+ +K+ +A + K+ E+KN+
Sbjct: 334 LQQLQDALNELTEEHSKA-------TQEWLEKQAQLEKELSAALQDKKCLEEKNEI---- 382
Query: 178 ILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQ--GLKDVGAKVTGFS---EGVVDS 232
LQ KL L +++ N P++ +V D+ Q LK A + + + V+
Sbjct: 383 ---LQGKLSQLEEHLSQLQDNP-PQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEM 438
Query: 233 VKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALG 292
++ + G + ++++SLI + S N+ K+ LE+ +
Sbjct: 439 LETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTA 498
Query: 293 VISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSK---TNTLDMQSSGFDALL 349
+++ S + ++ + + G+ A + TL Q L
Sbjct: 499 QVASLTS--------ELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLR 550
Query: 350 HEIQEIRETQARLEESFETLKEHYQ---RDYSLIMQTLQEER-----------YRCERLE 395
H+++++ + + E+ + + E + +D++ + T EER + E LE
Sbjct: 551 HQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALE 610
Query: 396 EQLNDLTELHQNEILNLKQELASMEEKIAYQSYERA---RDIQEALEACQTRISKMELQQ 452
++ E+ Q ++ + S + + E+A R ++E L+AC ++ E +
Sbjct: 611 KEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEE-LQAC-VETARQEQHE 668
Query: 453 QQQQVVQLE 461
Q QV +LE
Sbjct: 669 AQAQVAELE 677
Score = 41.2 bits (95), Expect = 0.002
Identities = 76/343 (22%), Positives = 134/343 (39%), Gaps = 58/343 (16%)
Query: 114 QRTKAA-IAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQVFEKKNQ 172
++ KAA + LQQ++ E AQT+ E +L+ ++ QA ++ +++++
Sbjct: 610 EKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQAC-VETARQEQHE 668
Query: 173 KSAQTILQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDS 232
AQ + +L+ +L +K E E+ Q KD ++ Q LK+ S
Sbjct: 669 AQAQ-VAELELQLRSEQQKATEKERVA---QEKDQLQEQLQALKE--------------S 710
Query: 233 VKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAG--KA 290
+K S + AA A+ + R I+ L + + LEE + G
Sbjct: 711 LKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEAR 770
Query: 291 LGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLH 350
L + + + + A + A S + ++ + D Q
Sbjct: 771 LQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQ--------- 821
Query: 351 EIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEE--------QLNDLT 402
QE + A +E TLKE ++ Q LQE + + +E Q N+L
Sbjct: 822 --QEEAQYGAMFQEQLMTLKEECEK----ARQELQEAKEKVAGIESHSELQISRQQNELA 875
Query: 403 ELHQNEILNLKQ-------------ELASMEEKIAYQSYERAR 432
ELH N L+Q +L++++EK+A S E AR
Sbjct: 876 ELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVAR 918
Score = 39.7 bits (91), Expect = 0.007
Identities = 86/389 (22%), Positives = 147/389 (37%), Gaps = 53/389 (13%)
Query: 84 VSSLAQTSSAV--ASSTDGSIHTDSVDG-TPDPQRTKAAIAHLQQKILKLTEQIK----- 135
+S+L+Q + AS G+ T V T + A I Q++ L +Q K
Sbjct: 475 ISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ 534
Query: 136 IAQTARDDNVAEY-----LKLANSADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHR 190
+AQT + A ++ +S+ KQ+ ++K+V EK+ QL E
Sbjct: 535 LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREA 594
Query: 191 KLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGA 250
LRE + + + K+ AK ++ ++ ++A SA +
Sbjct: 595 SLRERDA---------ALKQLEALEKEKAAK--------LEILQQQLQVANEARDSAQTS 637
Query: 251 VVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQSS---PKYGSEE 307
V RE A L R + + E Q A L + S Q + + E+
Sbjct: 638 VTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEK 697
Query: 308 DCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFE 367
D + +K + + + DAL +E + + L+
Sbjct: 698 D---------QLQEQLQALKESLKVTKGSLEEEKRRAADAL----EEQQRCISELKAETR 744
Query: 368 TLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQS 427
+L E ++R+ + L+EER + LE +L L E HQ E L++ELA E +A Q
Sbjct: 745 SLVEQHKRE----RKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELA---EAMAAQH 797
Query: 428 YERARDIQEALEACQTRISKMELQQQQQQ 456
+ Q E R + QQ++ Q
Sbjct: 798 TAESECEQLVKEVAAWRERYEDSQQEEAQ 826
Score = 34.7 bits (78), Expect = 0.23
Identities = 27/119 (22%), Positives = 53/119 (44%), Gaps = 11/119 (9%)
Query: 354 EIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLK 413
++ E QA+L + E EHY+ ++ + + L+EQL L +L +
Sbjct: 1592 QLNELQAQLSQK-EQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKE-----N 1645
Query: 414 QELASMEEKIAYQSYERARDIQEALEAC-----QTRISKMELQQQQQQVVQLEGLENAT 467
+EL + E++ ++ + +EA + C Q R + ++ QQ+ L + AT
Sbjct: 1646 KELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVAT 1704
Score = 34.3 bits (77), Expect = 0.30
Identities = 27/116 (23%), Positives = 59/116 (50%), Gaps = 7/116 (6%)
Query: 349 LHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNE 408
L + Q+++ +++++ L E D S L+E ++L++ LN+LTE H
Sbjct: 296 LKQCQDLKTEKSQMDRKINQLSEE-NGDLSF---KLREFASHLQQLQDALNELTEEHSKA 351
Query: 409 ILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKME--LQQQQQQVVQLEG 462
++ A +E++++ + + + ++E E Q ++S++E L Q Q Q +G
Sbjct: 352 TQEWLEKQAQLEKELS-AALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKG 406
Score = 33.5 bits (75), Expect = 0.51
Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 15/123 (12%)
Query: 357 ETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEE-------QLNDLTELHQNEI 409
E + RL+ + + + + L E+ + + L + Q+ +L EL Q +
Sbjct: 1029 ELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQT-V 1087
Query: 410 LNLKQELASMEEKIAY------QSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGL 463
LK++LA E++ A ++ R LEA + +SK+E Q Q+QQ Q + L
Sbjct: 1088 KQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ-EQADSL 1146
Query: 464 ENA 466
E +
Sbjct: 1147 ERS 1149
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 44.3 bits (103), Expect = 3e-04
Identities = 72/375 (19%), Positives = 148/375 (39%), Gaps = 35/375 (9%)
Query: 105 DSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIK 164
D ++G+ + + K L++ KL +K+AQ + D E +L K++ I
Sbjct: 1038 DDLEGSLEQE--KKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF-EIS 1094
Query: 165 QVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQN---------GIPRQPKDVFRDMHQGL 215
+ K + A I QLQKK++ ++ E+E+ +Q D+ R++ + +
Sbjct: 1095 NLQSKIEDEQALGI-QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE-I 1152
Query: 216 KDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSA------ 269
+ + G + ++ K + F + A + A+L + S
Sbjct: 1153 SERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQ 1212
Query: 270 -DNIPNLKDSLEEGQVDDAGKALGVISNFQ--SSPKYGSEEDCSSATS--GSVGANSTTG 324
DN+ +K LE+ + + + + SN + S K E+ C + + +
Sbjct: 1213 IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQ 1272
Query: 325 GIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESF----ETLKEHYQRDY--- 377
+ +++ L +S F L E + + +R +++F E LK + +
Sbjct: 1273 QRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAK 1332
Query: 378 SLIMQTLQEERYRCERLEEQLNDLTELH---QNEILNLKQELASMEEKIAYQSYERARDI 434
+ + LQ R+ C+ L EQ + E Q + E+A K + +R ++
Sbjct: 1333 NALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEEL 1392
Query: 435 QEALEACQTRISKME 449
+EA + R+ E
Sbjct: 1393 EEAKKKLAQRLQAAE 1407
Score = 38.1 bits (87), Expect = 0.021
Identities = 101/481 (20%), Positives = 190/481 (39%), Gaps = 62/481 (12%)
Query: 30 EMTAVMQSGRPRSSSTTDAPTSSAMMEIACAAAAAAAACLPGEEGTAERIER-LEVSSLA 88
E + ++ + RS + + S +E A A +A E +++ R LE ++L
Sbjct: 1131 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1190
Query: 89 QTSSAVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEY 148
++A +T H DSV + + ++QK+ K ++K+ NV
Sbjct: 1191 HEATA---ATLRKKHADSVAELGEQIDN---LQRVKQKLEKEKSEMKMEIDDLASNVETV 1244
Query: 149 LKLANSADKQQAARIKQVFEKKNQKSAQTIL---------QLQKKLEHYHRKLREVE--- 196
K + +K Q+ E K+++ Q L +LQ + + R+L E E
Sbjct: 1245 SKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALV 1304
Query: 197 ------QNGIPRQPKDVFRDMHQGLKDVGAKVTGF--SEGVVDSVKGGFSSFSQATHSAA 248
+ +Q +++ R + + +K A S D ++ + ++
Sbjct: 1305 SQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQ 1364
Query: 249 GAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQS-SPKYGSEE 307
A+ E+A R K+ D I ++ LEE + A + + ++ + K S E
Sbjct: 1365 RALSKANTEVAQW-RTKY-ETDAIQRTEE-LEEAKKKLAQRLQAAEEHVEAVNAKCASLE 1421
Query: 308 DCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEI-QEIRETQARLEESF 366
V + V +++ LD + FD +L E Q+ ET A LE S
Sbjct: 1422 KTKQRLQNEVEDLM----LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1477
Query: 367 ETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQ 426
+ + +L E ++ + E+ D E + E NL+QE++ + E+IA
Sbjct: 1478 KEAR------------SLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA-- 1523
Query: 427 SYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATA--RNLLGKLINILLAVMA 484
E + I E + K++ Q +Q++ LE A A + GK++ I L +
Sbjct: 1524 --EGGKRIHE--------LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573
Query: 485 V 485
V
Sbjct: 1574 V 1574
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 44.3 bits (103), Expect = 3e-04
Identities = 72/375 (19%), Positives = 148/375 (39%), Gaps = 35/375 (9%)
Query: 105 DSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIK 164
D ++G+ + + K L++ KL +K+AQ + D E +L K++ I
Sbjct: 1038 DDLEGSLEQE--KKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF-EIS 1094
Query: 165 QVFEKKNQKSAQTILQLQKKLEHYHRKLREVEQN---------GIPRQPKDVFRDMHQGL 215
+ K + A I QLQKK++ ++ E+E+ +Q D+ R++ + +
Sbjct: 1095 NLQSKIEDEQALGI-QLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE-I 1152
Query: 216 KDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSA------ 269
+ + G + ++ K + F + A + A+L + S
Sbjct: 1153 SERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQ 1212
Query: 270 -DNIPNLKDSLEEGQVDDAGKALGVISNFQ--SSPKYGSEEDCSSATS--GSVGANSTTG 324
DN+ +K LE+ + + + + SN + S K E+ C + + +
Sbjct: 1213 IDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQ 1272
Query: 325 GIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESF----ETLKEHYQRDY--- 377
+ +++ L +S F L E + + +R +++F E LK + +
Sbjct: 1273 QRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQLEEEIKAK 1332
Query: 378 SLIMQTLQEERYRCERLEEQLNDLTELH---QNEILNLKQELASMEEKIAYQSYERARDI 434
+ + LQ R+ C+ L EQ + E Q + E+A K + +R ++
Sbjct: 1333 NALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEEL 1392
Query: 435 QEALEACQTRISKME 449
+EA + R+ E
Sbjct: 1393 EEAKKKLAQRLQAAE 1407
Score = 38.1 bits (87), Expect = 0.021
Identities = 101/481 (20%), Positives = 190/481 (39%), Gaps = 62/481 (12%)
Query: 30 EMTAVMQSGRPRSSSTTDAPTSSAMMEIACAAAAAAAACLPGEEGTAERIER-LEVSSLA 88
E + ++ + RS + + S +E A A +A E +++ R LE ++L
Sbjct: 1131 ERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQ 1190
Query: 89 QTSSAVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEY 148
++A +T H DSV + + ++QK+ K ++K+ NV
Sbjct: 1191 HEATA---ATLRKKHADSVAELGEQIDN---LQRVKQKLEKEKSEMKMEIDDLASNVETV 1244
Query: 149 LKLANSADKQQAARIKQVFEKKNQKSAQTIL---------QLQKKLEHYHRKLREVE--- 196
K + +K Q+ E K+++ Q L +LQ + + R+L E E
Sbjct: 1245 SKAKGNLEKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALV 1304
Query: 197 ------QNGIPRQPKDVFRDMHQGLKDVGAKVTGF--SEGVVDSVKGGFSSFSQATHSAA 248
+ +Q +++ R + + +K A S D ++ + ++
Sbjct: 1305 SQLSRGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQ 1364
Query: 249 GAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALGVISNFQS-SPKYGSEE 307
A+ E+A R K+ D I ++ LEE + A + + ++ + K S E
Sbjct: 1365 RALSKANTEVAQW-RTKY-ETDAIQRTEE-LEEAKKKLAQRLQAAEEHVEAVNAKCASLE 1421
Query: 308 DCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEI-QEIRETQARLEESF 366
V + V +++ LD + FD +L E Q+ ET A LE S
Sbjct: 1422 KTKQRLQNEVEDLM----LDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQ 1477
Query: 367 ETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQ 426
+ + +L E ++ + E+ D E + E NL+QE++ + E+IA
Sbjct: 1478 KEAR------------SLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIA-- 1523
Query: 427 SYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATA--RNLLGKLINILLAVMA 484
E + I E + K++ Q +Q++ LE A A + GK++ I L +
Sbjct: 1524 --EGGKRIHE--------LEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQ 1573
Query: 485 V 485
V
Sbjct: 1574 V 1574
>gi|219555718 synaptonemal complex central element protein 1 isoform
4 [Homo sapiens]
Length = 351
Score = 43.9 bits (102), Expect = 4e-04
Identities = 32/140 (22%), Positives = 63/140 (45%), Gaps = 3/140 (2%)
Query: 319 ANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYS 378
A T G + + +T + ++ ++Q++ + R+E + E Q+
Sbjct: 10 AEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINE-VQQAKK 68
Query: 379 LIMQTLQEERYRCERLEEQLNDL--TELHQNEILNLKQELASMEEKIAYQSYERARDIQE 436
+ L E R CE L+++L+ L ++H EIL+ KQE + + A
Sbjct: 69 KANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHT 128
Query: 437 ALEACQTRISKMELQQQQQQ 456
L+ C+ RIS + LQ ++++
Sbjct: 129 MLQECKERISALNLQIEEEK 148
>gi|219555716 synaptonemal complex central element protein 1 isoform
3 [Homo sapiens]
Length = 318
Score = 43.9 bits (102), Expect = 4e-04
Identities = 32/140 (22%), Positives = 63/140 (45%), Gaps = 3/140 (2%)
Query: 319 ANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYS 378
A T G + + +T + ++ ++Q++ + R+E + E Q+
Sbjct: 10 AEPTAGAVDRAEKAGGQDTSSQKIEDLMEMVQKLQKVGSLEPRVEVLINRINE-VQQAKK 68
Query: 379 LIMQTLQEERYRCERLEEQLNDL--TELHQNEILNLKQELASMEEKIAYQSYERARDIQE 436
+ L E R CE L+++L+ L ++H EIL+ KQE + + A
Sbjct: 69 KANKDLGEARTICEALQKELDSLHGEKVHLKEILSKKQETLRILRLHCQEKESEAHRKHT 128
Query: 437 ALEACQTRISKMELQQQQQQ 456
L+ C+ RIS + LQ ++++
Sbjct: 129 MLQECKERISALNLQIEEEK 148
>gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]
Length = 717
Score = 43.9 bits (102), Expect = 4e-04
Identities = 30/94 (31%), Positives = 55/94 (58%), Gaps = 7/94 (7%)
Query: 371 EHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEIL-NLKQELASMEEKI--AYQS 427
E Q + + ++ER RC LE ++ +L H+N+ L +L QE ++++++ QS
Sbjct: 246 EQLQEENFRLESGREDERLRCAELEREVAELQ--HRNQALTSLAQEAQALKDEMDELRQS 303
Query: 428 YERARDIQEALEACQTRISKMELQQQQQQVVQLE 461
ERA ++ L +C+ R+ EL++ ++QV QLE
Sbjct: 304 SERAGQLEATLTSCRRRLG--ELRELRRQVRQLE 335
>gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]
Length = 719
Score = 43.9 bits (102), Expect = 4e-04
Identities = 30/94 (31%), Positives = 55/94 (58%), Gaps = 7/94 (7%)
Query: 371 EHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEIL-NLKQELASMEEKI--AYQS 427
E Q + + ++ER RC LE ++ +L H+N+ L +L QE ++++++ QS
Sbjct: 246 EQLQEENFRLESGREDERLRCAELEREVAELQ--HRNQALTSLAQEAQALKDEMDELRQS 303
Query: 428 YERARDIQEALEACQTRISKMELQQQQQQVVQLE 461
ERA ++ L +C+ R+ EL++ ++QV QLE
Sbjct: 304 SERAGQLEATLTSCRRRLG--ELRELRRQVRQLE 335
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 43.5 bits (101), Expect = 5e-04
Identities = 42/183 (22%), Positives = 80/183 (43%), Gaps = 12/183 (6%)
Query: 287 AGKALGVISNFQSSPKYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFD 346
+G + G S + P+ + A S VGA+ G + L+ Q
Sbjct: 43 SGGSGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQ 102
Query: 347 ALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQ 406
HE ++++ Q LE L++ Q+D + LQ+E+++ +E +L +HQ
Sbjct: 103 QPQHE--QLQQPQPHLE-----LQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQ 155
Query: 407 NEILNLKQ-----ELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLE 461
+ L +Q L +E++ Q + + +Q+ + Q + LQQQQ+Q+ Q +
Sbjct: 156 QQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQ 215
Query: 462 GLE 464
L+
Sbjct: 216 LLQ 218
Score = 43.5 bits (101), Expect = 5e-04
Identities = 31/126 (24%), Positives = 64/126 (50%), Gaps = 8/126 (6%)
Query: 348 LLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQN 407
L+H+ Q+++ Q + ++ + +E Q + Q LQ++ E+L++Q+ + L Q
Sbjct: 152 LMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQ----EQLQQQVQEQQLLQQQ 207
Query: 408 EILNLKQELASMEEKIAYQSY----ERARDIQEALEACQTRISKMELQQQQQQVVQLEGL 463
+ +Q+L +E++ Q + E+ + Q+ L Q + +L QQQQ +Q + L
Sbjct: 208 QEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLL 267
Query: 464 ENATAR 469
E A+
Sbjct: 268 EQQQAQ 273
Score = 29.6 bits (65), Expect = 7.3
Identities = 24/109 (22%), Positives = 57/109 (52%), Gaps = 12/109 (11%)
Query: 349 LHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNE 408
L + Q +++ + ++ F+ +E Q+ L++ LQ++ +L++QL + +
Sbjct: 211 LQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLL--LQQQG----QLQQQLLQQQQAQLQQ 264
Query: 409 ILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQV 457
L L+Q+ A +++++ Q E+ + Q+ Q + + + Q QQQQ+
Sbjct: 265 QL-LEQQQAQLQQQLLLQQQEQLQQQQQ-----QQLLQQQQEQLQQQQL 307
>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
Length = 790
Score = 43.5 bits (101), Expect = 5e-04
Identities = 58/241 (24%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 257 EIASLIRNKFGSADNIP---NLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSA- 312
E A N G D+I N+K + EE +V+ + ++ + +SS + C A
Sbjct: 131 ECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSS-----LVVDRESS-----HDGCQDAL 180
Query: 313 --------TSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRE------- 357
TS + + + + ++ N L++ L + Q+ R
Sbjct: 181 NILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFV 240
Query: 358 TQARLEESFETLKEHYQRDYSLIMQTLQEER-YRCERLEEQLNDLTELHQNEIL--NLKQ 414
TQ + + K Y+ LI L+ ER ++ E+L EQL EL Q ++L + ++
Sbjct: 241 TQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQER 300
Query: 415 ELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGK 474
EL + EK+ + + +R + E L+A T + Q Q Q EG A++L+ K
Sbjct: 301 ELTQLREKLR-EGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCR--LAQHLVQK 357
Query: 475 L 475
L
Sbjct: 358 L 358
>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
sapiens]
Length = 790
Score = 43.5 bits (101), Expect = 5e-04
Identities = 58/241 (24%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 257 EIASLIRNKFGSADNIP---NLKDSLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSA- 312
E A N G D+I N+K + EE +V+ + ++ + +SS + C A
Sbjct: 131 ECAITCSNSHGPCDSIQPHKNIKITFEEDKVNSS-----LVVDRESS-----HDGCQDAL 180
Query: 313 --------TSGSVGANSTTGGIAVGASSSKTNTLDMQSSGFDALLHEIQEIRE------- 357
TS + + + + ++ N L++ L + Q+ R
Sbjct: 181 NILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFV 240
Query: 358 TQARLEESFETLKEHYQRDYSLIMQTLQEER-YRCERLEEQLNDLTELHQNEIL--NLKQ 414
TQ + + K Y+ LI L+ ER ++ E+L EQL EL Q ++L + ++
Sbjct: 241 TQVACFLAKQQNKYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQER 300
Query: 415 ELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGK 474
EL + EK+ + + +R + E L+A T + Q Q Q EG A++L+ K
Sbjct: 301 ELTQLREKLR-EGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCR--LAQHLVQK 357
Query: 475 L 475
L
Sbjct: 358 L 358
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 43.1 bits (100), Expect = 6e-04
Identities = 37/145 (25%), Positives = 70/145 (48%), Gaps = 20/145 (13%)
Query: 330 ASSSKTNTLDMQSSGFDALLH----EIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQ 385
A K QSSG H E+QE++ET + E ++L+ + + +TL
Sbjct: 1450 AQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVEN----LQKTLS 1505
Query: 386 EERYRCERLEEQLNDLTELHQNEILNLKQEL---ASMEEKIAYQSYERARDIQEALEACQ 442
E+ L+EQ L Q+E+ L+Q+L + EE++ Q E+ ++A+ A +
Sbjct: 1506 EKETEARNLQEQTVQL----QSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAK 1561
Query: 443 TRIS-----KMELQQQQQQVVQLEG 462
++I+ K +L ++ +++ Q G
Sbjct: 1562 SKIAHLAGVKDQLTKENEELKQRNG 1586
Score = 40.8 bits (94), Expect = 0.003
Identities = 43/140 (30%), Positives = 70/140 (50%), Gaps = 12/140 (8%)
Query: 333 SKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCE 392
S+T T SS + L HEI +++ +LE E + + +L +Q L +R
Sbjct: 829 SETETKQRLSSQIEKLEHEISHLKK---KLENEVE---QRHTLTRNLDVQLLDTKRQLDT 882
Query: 393 RLEEQLN--DLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEA-LEACQTRISKME 449
LN +L + Q EI LKQ L++ME ++A QS +R Q + E +S +
Sbjct: 883 ETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVS--Q 940
Query: 450 LQQQQQQVVQL-EGLENATA 468
L+Q ++QV L E L+ +T+
Sbjct: 941 LRQTEEQVNDLKERLKTSTS 960
Score = 39.3 bits (90), Expect = 0.009
Identities = 44/191 (23%), Positives = 79/191 (41%), Gaps = 24/191 (12%)
Query: 83 EVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARD 142
++S L +T S+V + ++ QR A+++ QQ EQ KIA A++
Sbjct: 1032 QLSELKKTLSSVQNEVQEAL-----------QRASTALSNEQQARRDCQEQAKIAVEAQN 1080
Query: 143 DNVAEYLKLANSADKQQAAR--------IKQVFEKKNQKSAQTILQLQKKLEHYHRKLRE 194
E + A + QAA+ ++Q E+ QK+ +L+ + E R L++
Sbjct: 1081 KYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKD 1140
Query: 195 VEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSK 254
+ R D+ + + + ++ S+ VV SVK G + S G +
Sbjct: 1141 EVSKCVCR-----CEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQ 1195
Query: 255 PREIASLIRNK 265
EI IR +
Sbjct: 1196 ILEILRFIRRE 1206
Score = 32.7 bits (73), Expect = 0.86
Identities = 40/170 (23%), Positives = 74/170 (43%), Gaps = 20/170 (11%)
Query: 352 IQEIRETQARLEESFETLK---EHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNE 408
++ +E +RLEE LK EH Q+ ++ L+E + + +EE+ ++ H +
Sbjct: 226 LENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAH-IK 284
Query: 409 ILNLKQELASMEE-------KIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLE 461
+ NL + A E + + ++ ++ EA +A Q + ++E + Q + LE
Sbjct: 285 LSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLE 344
Query: 462 -------GLENATARNLLGKLINILLA--VMAVLLVFVSTVANCVVPLMK 502
LENA K +L+ +A + + VA V P MK
Sbjct: 345 KIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMK 394
Score = 32.7 bits (73), Expect = 0.86
Identities = 42/173 (24%), Positives = 78/173 (45%), Gaps = 31/173 (17%)
Query: 330 ASSSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFETLK------EHYQRDYSLIMQT 383
AS S T Q S + + + ++R+T+ ++ + E LK E YQ + + ++
Sbjct: 916 ASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEES 975
Query: 384 LQEERYRCE--------RLEEQLNDLTELHQN--EILNLKQELA--------SMEEKIAY 425
L +E+ E RL+E T+L + E+ KQEL SME++++
Sbjct: 976 LNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSE 1035
Query: 426 QSYERA---RDIQEALEACQTRISKMELQQ---QQQQVVQLEGLENATARNLL 472
+ ++QEAL+ T +S + + Q+Q + +E +N R L+
Sbjct: 1036 LKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEA-QNKYERELM 1087
Score = 32.3 bits (72), Expect = 1.1
Identities = 71/415 (17%), Positives = 156/415 (37%), Gaps = 59/415 (14%)
Query: 83 EVSSLAQTSS----AVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQ 138
E+++L Q S VAS + D + + ++++ L E++K +
Sbjct: 900 EIATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTST 959
Query: 139 TARDDNVAEYLKLANSAD------KQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKL 192
+ NV +Y + S + KQ +++ E + ++SA+ QL+KKL ++
Sbjct: 960 S----NVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEK 1015
Query: 193 REVEQNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVV 252
+E++ + + M Q L ++ ++ V ++++ ++ S A
Sbjct: 1016 QELQDD-----KRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALS--NEQQARRDC 1068
Query: 253 SKPREIASLIRNKF------------------GSADNIPNLKDSLEEGQVDDAGKALGVI 294
+ +IA +NK+ + +++ LEE + L
Sbjct: 1069 QEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECK 1128
Query: 295 SNFQSSPKYGSEE--DCSSATSGSVGAN------------STTGGIAVGASSSKTNTLDM 340
++++ + +E C N + G +L
Sbjct: 1129 ASWEERERMLKDEVSKCVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSE 1188
Query: 341 QSSGFDALLHEIQEIRETQARLEESFETLKE---HYQRDYSLIMQTLQE--ERYRCERLE 395
+ + +L ++ IR + E FE + Y++ L+ + LQE + ER +
Sbjct: 1189 EGKSQEQILEILRFIRREKEIAETRFEVAQVESLRYRQRVELLERELQELQDSLNAEREK 1248
Query: 396 EQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMEL 450
Q+ T + Q+E L K E ++ + E +++ L+ Q ++ K+EL
Sbjct: 1249 VQVTAKT-MAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLEL 1302
Score = 31.2 bits (69), Expect = 2.5
Identities = 20/88 (22%), Positives = 46/88 (52%), Gaps = 2/88 (2%)
Query: 107 VDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANSADKQQAARIKQV 166
V+ T + Q + + L ++ LTE+ K + A+D N+A + + ++ +A K+
Sbjct: 69 VNETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAE--KRD 126
Query: 167 FEKKNQKSAQTILQLQKKLEHYHRKLRE 194
+ N++ +Q + L + ++ + KL+E
Sbjct: 127 LIRTNERLSQELEYLTEDVKRLNEKLKE 154
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 42.7 bits (99), Expect = 8e-04
Identities = 79/391 (20%), Positives = 152/391 (38%), Gaps = 67/391 (17%)
Query: 115 RTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLANS--------ADKQQAARIKQV 166
R ++ HLQ++ + E+ + Q + +L + Q+ +++Q
Sbjct: 1486 RKTVSLEHLQREYASVKEENERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEVKLRQQ 1545
Query: 167 FEKKNQKSAQTI---LQLQKKLEHYHRKLREVEQNGIPRQPKDVFRDMHQGLKDVGAKVT 223
+N K Q++ L+ +KL+ HR+LRE G Q D FRD+H L ++ A
Sbjct: 1546 LLSQNDKLLQSLRVELKAYEKLDEEHRRLREASGEGWKGQ--DPFRDLHSLLMEIQALRL 1603
Query: 224 GFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKD------ 277
+ S S+ K +E A + + S +P D
Sbjct: 1604 QLERSIETS-----STLQSRLKEQLARGAEKAQEGALTLAVQAVSIPEVPLQPDKHDGDK 1658
Query: 278 ----SLEEGQVDDAGKALGVISNFQSSPKYGSEEDCSSATSGSVGANST------TGGIA 327
S + D+ +A+ S ++ P G++ D S SGS A ST G
Sbjct: 1659 YPMESDNSFDLFDSSQAVTPKSVSETPPLSGNDTDSLSCDSGS-SATSTPCVSRLVTGHH 1717
Query: 328 VGASSSKTNTLDMQSSGFDALLHEIQ-----------EIRETQARLEESFETLKEH---- 372
+ AS + + L + ++ALL +I + +E + + T H
Sbjct: 1718 LWASKNGRHVLGL-IEDYEALLKQISQGQRLLAEMDIQTQEAPSSTSQELGTKGPHPAPL 1776
Query: 373 --YQRDYSLIMQTLQEERYRCE---RLEEQLNDLTELHQNEILNLKQELASMEEKIAYQS 427
+ S TL+E R + R+ + LH +I +K E+ + +K+
Sbjct: 1777 SKFVSSVSTAKLTLEEAYRRLKLLWRVSLPEDGQCPLHCEQIGEMKAEVTKLHKKL---- 1832
Query: 428 YERARDIQEALEACQTRISKMELQQQQQQVV 458
+E+ + +Q ++ ++L ++Q++V+
Sbjct: 1833 FEQEKKLQNTMKL-------LQLSKRQEKVI 1856
Score = 32.0 bits (71), Expect = 1.5
Identities = 42/166 (25%), Positives = 71/166 (42%), Gaps = 45/166 (27%)
Query: 332 SSKTNTLDMQSSGFDALLHEIQEIRETQARLEESFET---LKEHYQRDYSLIMQTLQEER 388
+ KT+ + + S D L+ IQEIR + RLEES +T L++ +R S +Q
Sbjct: 1380 TEKTSVM-VNSFSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQGSTSIF 1438
Query: 389 YRCERLEEQLNDLTELH----QNEILN------------------------------LKQ 414
L L +E+H QN+ LN L++
Sbjct: 1439 ASGSELHSSLT--SEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEHLQR 1496
Query: 415 ELASME---EKIAYQSYERARDIQEALEACQTRISKMELQQQQQQV 457
E AS++ E++ + E+ R Q+ ++ + R S EL + Q++V
Sbjct: 1497 EYASVKEENERLQKEGSEKERHNQQLIQ--EVRCSGQELSRVQEEV 1540
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 42.7 bits (99), Expect = 8e-04
Identities = 39/129 (30%), Positives = 68/129 (52%), Gaps = 14/129 (10%)
Query: 339 DMQSSGFDALLHEIQE--IRETQARLEESFETLKEHYQRDYSLIMQTLQEERYR--CERL 394
+++++ +LL+ QE +RE + RL E E L+E +R QEER R ERL
Sbjct: 183 EVENNQMLSLLNRRQEERLREQEERLREQEERLREQEER------LCEQEERLREQEERL 236
Query: 395 EEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKME--LQQ 452
EQ L E + + ++ L EE++ Q ER R+ +E L + R+ + E L++
Sbjct: 237 REQEERLCE-QEERLREHEERLCEQEERLCEQE-ERLREQEERLHEQEERLCEQEERLRE 294
Query: 453 QQQQVVQLE 461
Q++++ + E
Sbjct: 295 QEERLCEQE 303
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/121 (28%), Positives = 62/121 (51%), Gaps = 10/121 (8%)
Query: 346 DALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE-L 404
+ L + + +RE + RL E E L E +R + ++E CE+ EE+L + E L
Sbjct: 220 ERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQ-EERLREQEERL 278
Query: 405 HQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKME--LQQQQQQVVQLEG 462
H+ E + L EE++ Q ER + +E L + R+ + E L++Q++++ + E
Sbjct: 279 HEQE-----ERLCEQEERLREQE-ERLCEQEERLREQEERLCEQEERLREQEERLCEQEK 332
Query: 463 L 463
L
Sbjct: 333 L 333
Score = 37.0 bits (84), Expect = 0.046
Identities = 34/139 (24%), Positives = 65/139 (46%), Gaps = 7/139 (5%)
Query: 346 DALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTE-L 404
+ L + + + E + RL E E L+E +R + ++E CE+ EE+L + E L
Sbjct: 269 ERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ-EERLREQEERL 327
Query: 405 HQNEILNLKQELASMEEKIAYQ-----SYERARDIQEALEACQTRISKMELQQQQQQVVQ 459
+ E L ++ L EK+ Q ER + + LE + + + L+QQ +++ Q
Sbjct: 328 CEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQ 387
Query: 460 LEGLENATARNLLGKLINI 478
E L+ L +++ +
Sbjct: 388 QETLQELERLRELERMLEL 406
Score = 33.5 bits (75), Expect = 0.51
Identities = 26/118 (22%), Positives = 56/118 (47%), Gaps = 7/118 (5%)
Query: 346 DALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELH 405
+ L + + + E + RL E E L E +R + ++E CE+ EE+L +
Sbjct: 255 ERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQ-EERLRE----Q 309
Query: 406 QNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGL 463
+ + ++ L EE++ Q E+ + LE + + + Q++Q+++++ E L
Sbjct: 310 EERLCEQEERLREQEERLCEQ--EKLPGQERLLEEVEKLLEQERRQEEQERLLERERL 365
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.126 0.340
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,052,616
Number of Sequences: 37866
Number of extensions: 777912
Number of successful extensions: 6374
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 565
Number of HSP's that attempted gapping in prelim test: 4723
Number of HSP's gapped (non-prelim): 2128
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.