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Search of human proteins with 18860920
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18860920 estrogen-related receptor alpha [Homo sapiens]
(423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 842 0.0
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 476 e-134
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 476 e-134
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 476 e-134
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 476 e-134
gi|238550159 estrogen-related receptor beta [Homo sapiens] 472 e-133
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 243 2e-64
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 243 2e-64
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 243 2e-64
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 243 2e-64
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens] 225 5e-59
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens] 209 5e-54
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens] 209 5e-54
gi|11415052 retinoid X receptor, beta [Homo sapiens] 205 7e-53
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 201 1e-51
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 196 3e-50
gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Hom... 189 5e-48
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 185 6e-47
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 182 7e-46
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom... 175 8e-44
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom... 175 8e-44
gi|110611914 progesterone receptor [Homo sapiens] 171 9e-43
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo... 171 2e-42
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof... 167 1e-41
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof... 167 1e-41
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof... 167 1e-41
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof... 167 1e-41
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof... 167 1e-41
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo... 167 1e-41
gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Ho... 165 6e-41
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 842 bits (2176), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAG 60
MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAG
Sbjct: 1 MSSQVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAG 60
Query: 61 PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE 120
PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE
Sbjct: 61 PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE 120
Query: 121 CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP 180
CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP
Sbjct: 121 CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP 180
Query: 181 LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTI 240
LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTI
Sbjct: 181 LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTI 240
Query: 241 SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAA 300
SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAA
Sbjct: 241 SWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAA 300
Query: 301 GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL 360
GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL
Sbjct: 301 GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL 360
Query: 361 EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA 420
EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA
Sbjct: 361 EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA 420
Query: 421 MMD 423
MMD
Sbjct: 421 MMD 423
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 476 bits (1226), Expect = e-134
Identities = 249/436 (57%), Positives = 310/436 (71%), Gaps = 44/436 (10%)
Query: 12 YIKAEPASP---------DSPKGSSETETE------------------PPVALAPGPAPT 44
+IK EP+SP SP GSS+ P + G P
Sbjct: 15 FIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPV 74
Query: 45 RCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFK 104
R L ++ Q + +L+S+PKRLCLVCGD+ASGYHYGVASCEACKAFFK
Sbjct: 75 RKL----YDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFK 130
Query: 105 RTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRR 164
RTIQG+IEYSCPA+NECEITKRRRK+CQACRF KCL+VGMLKEGVRLDRVRGGRQKYKRR
Sbjct: 131 RTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRR 190
Query: 165 PEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPA 224
+ + P+ P P P N +VSHLLV EPEK+YAMPDP PD + A
Sbjct: 191 IDAENSPYLNPQLVQP---------AKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKA 241
Query: 225 VATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDEL 284
+ TLCDL DRE+VV I WAK IPGFS+LSL+DQMS+LQS WME+L+LGV RSL +DEL
Sbjct: 242 LTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDEL 301
Query: 285 AFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIED 344
+A+D ++DE+ ++ AGL +L A+LQLV++ ++++LE+EE+V LKA+ALANSDS+HIED
Sbjct: 302 VYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIED 361
Query: 345 AEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKL 404
EAV++L++ LHEAL +YEAG+ + RRAG++L+TLPLLRQT+ K + HFY +KL
Sbjct: 362 VEAVQKLQDVLHEALQDYEAGQ----HMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKL 417
Query: 405 EGKVPMHKLFLEMLEA 420
EGKVPMHKLFLEMLEA
Sbjct: 418 EGKVPMHKLFLEMLEA 433
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 476 bits (1226), Expect = e-134
Identities = 249/436 (57%), Positives = 310/436 (71%), Gaps = 44/436 (10%)
Query: 12 YIKAEPASP---------DSPKGSSETETE------------------PPVALAPGPAPT 44
+IK EP+SP SP GSS+ P + G P
Sbjct: 15 FIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPV 74
Query: 45 RCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFK 104
R L ++ Q + +L+S+PKRLCLVCGD+ASGYHYGVASCEACKAFFK
Sbjct: 75 RKL----YDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFK 130
Query: 105 RTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRR 164
RTIQG+IEYSCPA+NECEITKRRRK+CQACRF KCL+VGMLKEGVRLDRVRGGRQKYKRR
Sbjct: 131 RTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRR 190
Query: 165 PEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPA 224
+ + P+ P P P N +VSHLLV EPEK+YAMPDP PD + A
Sbjct: 191 IDAENSPYLNPQLVQP---------AKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKA 241
Query: 225 VATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDEL 284
+ TLCDL DRE+VV I WAK IPGFS+LSL+DQMS+LQS WME+L+LGV RSL +DEL
Sbjct: 242 LTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDEL 301
Query: 285 AFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIED 344
+A+D ++DE+ ++ AGL +L A+LQLV++ ++++LE+EE+V LKA+ALANSDS+HIED
Sbjct: 302 VYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIED 361
Query: 345 AEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKL 404
EAV++L++ LHEAL +YEAG+ + RRAG++L+TLPLLRQT+ K + HFY +KL
Sbjct: 362 VEAVQKLQDVLHEALQDYEAGQ----HMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKL 417
Query: 405 EGKVPMHKLFLEMLEA 420
EGKVPMHKLFLEMLEA
Sbjct: 418 EGKVPMHKLFLEMLEA 433
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 476 bits (1226), Expect = e-134
Identities = 249/436 (57%), Positives = 310/436 (71%), Gaps = 44/436 (10%)
Query: 12 YIKAEPASP---------DSPKGSSETETE------------------PPVALAPGPAPT 44
+IK EP+SP SP GSS+ P + G P
Sbjct: 38 FIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPV 97
Query: 45 RCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFK 104
R L ++ Q + +L+S+PKRLCLVCGD+ASGYHYGVASCEACKAFFK
Sbjct: 98 RKL----YDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFK 153
Query: 105 RTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRR 164
RTIQG+IEYSCPA+NECEITKRRRK+CQACRF KCL+VGMLKEGVRLDRVRGGRQKYKRR
Sbjct: 154 RTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRR 213
Query: 165 PEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPA 224
+ + P+ P P P N +VSHLLV EPEK+YAMPDP PD + A
Sbjct: 214 IDAENSPYLNPQLVQP---------AKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKA 264
Query: 225 VATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDEL 284
+ TLCDL DRE+VV I WAK IPGFS+LSL+DQMS+LQS WME+L+LGV RSL +DEL
Sbjct: 265 LTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDEL 324
Query: 285 AFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIED 344
+A+D ++DE+ ++ AGL +L A+LQLV++ ++++LE+EE+V LKA+ALANSDS+HIED
Sbjct: 325 VYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIED 384
Query: 345 AEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKL 404
EAV++L++ LHEAL +YEAG+ + RRAG++L+TLPLLRQT+ K + HFY +KL
Sbjct: 385 VEAVQKLQDVLHEALQDYEAGQ----HMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKL 440
Query: 405 EGKVPMHKLFLEMLEA 420
EGKVPMHKLFLEMLEA
Sbjct: 441 EGKVPMHKLFLEMLEA 456
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 476 bits (1226), Expect = e-134
Identities = 249/436 (57%), Positives = 310/436 (71%), Gaps = 44/436 (10%)
Query: 12 YIKAEPASP---------DSPKGSSETETE------------------PPVALAPGPAPT 44
+IK EP+SP SP GSS+ P + G P
Sbjct: 15 FIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPV 74
Query: 45 RCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFK 104
R L ++ Q + +L+S+PKRLCLVCGD+ASGYHYGVASCEACKAFFK
Sbjct: 75 RKL----YDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFK 130
Query: 105 RTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRR 164
RTIQG+IEYSCPA+NECEITKRRRK+CQACRF KCL+VGMLKEGVRLDRVRGGRQKYKRR
Sbjct: 131 RTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRR 190
Query: 165 PEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPA 224
+ + P+ P P P N +VSHLLV EPEK+YAMPDP PD + A
Sbjct: 191 IDAENSPYLNPQLVQP---------AKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKA 241
Query: 225 VATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDEL 284
+ TLCDL DRE+VV I WAK IPGFS+LSL+DQMS+LQS WME+L+LGV RSL +DEL
Sbjct: 242 LTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDEL 301
Query: 285 AFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIED 344
+A+D ++DE+ ++ AGL +L A+LQLV++ ++++LE+EE+V LKA+ALANSDS+HIED
Sbjct: 302 VYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIED 361
Query: 345 AEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKL 404
EAV++L++ LHEAL +YEAG+ + RRAG++L+TLPLLRQT+ K + HFY +KL
Sbjct: 362 VEAVQKLQDVLHEALQDYEAGQ----HMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKL 417
Query: 405 EGKVPMHKLFLEMLEA 420
EGKVPMHKLFLEMLEA
Sbjct: 418 EGKVPMHKLFLEMLEA 433
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 472 bits (1215), Expect = e-133
Identities = 252/432 (58%), Positives = 308/432 (71%), Gaps = 38/432 (8%)
Query: 12 YIKAEPASPDS---------PKGSSETE--------------TEPPVALAPGPAPTRCLP 48
+IK EP+SP S P GSS+ PP+ G T C
Sbjct: 15 FIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPPMFAGAGLGGTPCRK 74
Query: 49 GHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQ 108
+ E+ G + +L+++PKRLCLVCGD+ASGYHYGVASCEACKAFFKRTIQ
Sbjct: 75 SY--EDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQ 132
Query: 109 GSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVD 168
G+IEYSCPA+NECEITKRRRK+CQACRF KCL+VGMLKEGVRLDRVRGGRQKYKRR + +
Sbjct: 133 GNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRLDSE 192
Query: 169 PLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATL 228
P+ L ++ +K P+ +VS+LLV EP+KLYAMP P P+G + A+ TL
Sbjct: 193 SSPYLS------LQISPPAKK---PLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTL 243
Query: 229 CDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAE 288
CDL DRE+VV I WAK IPGFSSLSL DQMS+LQS WME+L+LG+ RSLP D+L +AE
Sbjct: 244 CDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAE 303
Query: 289 DLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAV 348
D ++DEE +R AGL EL A+LQLVRR + L++E+EE+V LKALALANSDS++IED EAV
Sbjct: 304 DYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIEDLEAV 363
Query: 349 EQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKV 408
++L++ LHEAL +YE + E R G+LLLTLPLLRQTA K + HFY VKL+GKV
Sbjct: 364 QKLQDLLHEALQDYELSQR----HEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGKV 419
Query: 409 PMHKLFLEMLEA 420
PMHKLFLEMLEA
Sbjct: 420 PMHKLFLEMLEA 431
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 243 bits (621), Expect = 2e-64
Identities = 154/433 (35%), Positives = 227/433 (52%), Gaps = 37/433 (8%)
Query: 10 PLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKL 69
P Y++ EP+ G + E PP P ++ + E G
Sbjct: 129 PYYLENEPS------GYTVREAGPPAFYRPNS-------DNRRQGGRERLASTNDKGSMA 175
Query: 70 VLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRK 129
+ S+ R C VC D ASGYHYGV SCE CKAFFKR+IQG +Y CPA+N+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
Query: 130 ACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVD-----PLPFPGPFPA-----G 179
+CQACR KC VGM+K G+R DR RGGR +R D + G A
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
Query: 180 PLAVAGGPRKTAA---PVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREI 236
PL + + + A + +VS LL EP LY+ DP P + L +L DRE+
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
Query: 237 VVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EE 295
V I+WAK +PGF L+L DQ+ +L+ W+E+L++G+ RS+ +L FA +L+LD +
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
Query: 296 GARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSV--------HIEDAEA 347
G G+ E+ LL R + + L+ EE+V LK++ L NS +E+ +
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
Query: 348 VEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGK 407
+ ++ + + + L+ A +AG + +R +LLL L +R + K + H Y +K +
Sbjct: 475 IHRVLDKITDTLIHLMA-KAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNV 533
Query: 408 VPMHKLFLEMLEA 420
VP++ L LEML+A
Sbjct: 534 VPLYDLLLEMLDA 546
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 243 bits (621), Expect = 2e-64
Identities = 154/433 (35%), Positives = 227/433 (52%), Gaps = 37/433 (8%)
Query: 10 PLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKL 69
P Y++ EP+ G + E PP P ++ + E G
Sbjct: 129 PYYLENEPS------GYTVREAGPPAFYRPNS-------DNRRQGGRERLASTNDKGSMA 175
Query: 70 VLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRK 129
+ S+ R C VC D ASGYHYGV SCE CKAFFKR+IQG +Y CPA+N+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
Query: 130 ACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVD-----PLPFPGPFPA-----G 179
+CQACR KC VGM+K G+R DR RGGR +R D + G A
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
Query: 180 PLAVAGGPRKTAA---PVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREI 236
PL + + + A + +VS LL EP LY+ DP P + L +L DRE+
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
Query: 237 VVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EE 295
V I+WAK +PGF L+L DQ+ +L+ W+E+L++G+ RS+ +L FA +L+LD +
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
Query: 296 GARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSV--------HIEDAEA 347
G G+ E+ LL R + + L+ EE+V LK++ L NS +E+ +
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
Query: 348 VEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGK 407
+ ++ + + + L+ A +AG + +R +LLL L +R + K + H Y +K +
Sbjct: 475 IHRVLDKITDTLIHLMA-KAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNV 533
Query: 408 VPMHKLFLEMLEA 420
VP++ L LEML+A
Sbjct: 534 VPLYDLLLEMLDA 546
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 243 bits (621), Expect = 2e-64
Identities = 154/433 (35%), Positives = 227/433 (52%), Gaps = 37/433 (8%)
Query: 10 PLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKL 69
P Y++ EP+ G + E PP P ++ + E G
Sbjct: 129 PYYLENEPS------GYTVREAGPPAFYRPNS-------DNRRQGGRERLASTNDKGSMA 175
Query: 70 VLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRK 129
+ S+ R C VC D ASGYHYGV SCE CKAFFKR+IQG +Y CPA+N+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
Query: 130 ACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVD-----PLPFPGPFPA-----G 179
+CQACR KC VGM+K G+R DR RGGR +R D + G A
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
Query: 180 PLAVAGGPRKTAA---PVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREI 236
PL + + + A + +VS LL EP LY+ DP P + L +L DRE+
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
Query: 237 VVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EE 295
V I+WAK +PGF L+L DQ+ +L+ W+E+L++G+ RS+ +L FA +L+LD +
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
Query: 296 GARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSV--------HIEDAEA 347
G G+ E+ LL R + + L+ EE+V LK++ L NS +E+ +
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
Query: 348 VEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGK 407
+ ++ + + + L+ A +AG + +R +LLL L +R + K + H Y +K +
Sbjct: 475 IHRVLDKITDTLIHLMA-KAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNV 533
Query: 408 VPMHKLFLEMLEA 420
VP++ L LEML+A
Sbjct: 534 VPLYDLLLEMLDA 546
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 243 bits (621), Expect = 2e-64
Identities = 154/433 (35%), Positives = 227/433 (52%), Gaps = 37/433 (8%)
Query: 10 PLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKL 69
P Y++ EP+ G + E PP P ++ + E G
Sbjct: 129 PYYLENEPS------GYTVREAGPPAFYRPNS-------DNRRQGGRERLASTNDKGSMA 175
Query: 70 VLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRK 129
+ S+ R C VC D ASGYHYGV SCE CKAFFKR+IQG +Y CPA+N+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
Query: 130 ACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVD-----PLPFPGPFPA-----G 179
+CQACR KC VGM+K G+R DR RGGR +R D + G A
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
Query: 180 PLAVAGGPRKTAA---PVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREI 236
PL + + + A + +VS LL EP LY+ DP P + L +L DRE+
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
Query: 237 VVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EE 295
V I+WAK +PGF L+L DQ+ +L+ W+E+L++G+ RS+ +L FA +L+LD +
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
Query: 296 GARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSV--------HIEDAEA 347
G G+ E+ LL R + + L+ EE+V LK++ L NS +E+ +
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
Query: 348 VEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGK 407
+ ++ + + + L+ A +AG + +R +LLL L +R + K + H Y +K +
Sbjct: 475 IHRVLDKITDTLIHLMA-KAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNV 533
Query: 408 VPMHKLFLEMLEA 420
VP++ L LEML+A
Sbjct: 534 VPLYDLLLEMLDA 546
>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
Length = 530
Score = 225 bits (574), Expect = 5e-59
Identities = 144/356 (40%), Positives = 200/356 (56%), Gaps = 21/356 (5%)
Query: 79 CLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTK 138
C VC D ASGYHYGV SCE CKAFFKR+IQG +Y CPA+N+C I K RRK+CQACR K
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 139 CLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGG--PRKTAAPVNA 196
C VGM+K G R +R G R ++R + L AG +GG PR ++A
Sbjct: 209 CYEVGMVKCGSRRERC-GYRLVRRQRSADEQL-----HCAGKAKRSGGHAPRVRELLLDA 262
Query: 197 -----LVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSS 251
LV LL EP + + P+ P + +L L D+E+V ISWAK IPGF
Sbjct: 263 LSPEQLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVE 321
Query: 252 LSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EEGARAAGLGELGAALL 310
LSL DQ+ +L+S WMEVL++G+ RS+ +L FA DLVLD +EG G+ E+ LL
Sbjct: 322 LSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLL 381
Query: 311 QLVRRLQALRLEREEYVLLKALALANSDSVHI----EDAEAVEQLREALHEA--LLEYEA 364
R + L+L+ +EY+ +KA+ L NS + +DA++ +L L+ L +
Sbjct: 382 ATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVI 441
Query: 365 GRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA 420
++G + R LL+ L +R + K + H +K + VP++ L LEML A
Sbjct: 442 AKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNA 497
>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 209 bits (531), Expect = 5e-54
Identities = 140/349 (40%), Positives = 195/349 (55%), Gaps = 26/349 (7%)
Query: 79 CLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTK 138
C VC D ASGYHYGV SCE CKAFFKR+IQG +Y CPA+N+C I K RRK+CQACR K
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 139 CLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGG--PRKTAAPVNA 196
C VGM+K G R +R G R ++R + L AG +GG PR ++A
Sbjct: 209 CYEVGMVKCGSRRERC-GYRLVRRQRSADEQL-----HCAGKAKRSGGHAPRVRELLLDA 262
Query: 197 -----LVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSS 251
LV LL EP + + P+ P + +L L D+E+V ISWAK IPGF
Sbjct: 263 LSPEQLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVE 321
Query: 252 LSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EEGARAAGLGELGAALL 310
LSL DQ+ +L+S WMEVL++G+ RS+ +L FA DLVLD +EG G+ E+ LL
Sbjct: 322 LSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLL 381
Query: 311 QLVRRLQALRLEREEYVLLKALALANSDSVHI----EDAEAVEQLREALHEA--LLEYEA 364
R + L+L+ +EY+ +KA+ L NS + +DA++ +L L+ L +
Sbjct: 382 ATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVI 441
Query: 365 GRAGPGGGAERRRAGRLLLTLPLLR----QTAGKVLAHFYGVKLEGKVP 409
++G + R LL+ L +R + A + L F G+K+E +P
Sbjct: 442 AKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF-GMKMETLLP 489
>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 209 bits (531), Expect = 5e-54
Identities = 140/349 (40%), Positives = 195/349 (55%), Gaps = 26/349 (7%)
Query: 79 CLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTK 138
C VC D ASGYHYGV SCE CKAFFKR+IQG +Y CPA+N+C I K RRK+CQACR K
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 139 CLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGG--PRKTAAPVNA 196
C VGM+K G R +R G R ++R + L AG +GG PR ++A
Sbjct: 209 CYEVGMVKCGSRRERC-GYRLVRRQRSADEQL-----HCAGKAKRSGGHAPRVRELLLDA 262
Query: 197 -----LVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSS 251
LV LL EP + + P+ P + +L L D+E+V ISWAK IPGF
Sbjct: 263 LSPEQLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVE 321
Query: 252 LSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EEGARAAGLGELGAALL 310
LSL DQ+ +L+S WMEVL++G+ RS+ +L FA DLVLD +EG G+ E+ LL
Sbjct: 322 LSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLL 381
Query: 311 QLVRRLQALRLEREEYVLLKALALANSDSVHI----EDAEAVEQLREALHEA--LLEYEA 364
R + L+L+ +EY+ +KA+ L NS + +DA++ +L L+ L +
Sbjct: 382 ATTSRFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLNAVTDALVWVI 441
Query: 365 GRAGPGGGAERRRAGRLLLTLPLLR----QTAGKVLAHFYGVKLEGKVP 409
++G + R LL+ L +R + A + L F G+K+E +P
Sbjct: 442 AKSGISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSF-GMKMETLLP 489
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 205 bits (521), Expect = 7e-53
Identities = 127/365 (34%), Positives = 188/365 (51%), Gaps = 36/365 (9%)
Query: 61 PGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNE 120
PG G GK RLC +CGD +SG HYGV SCE CK FFKRTI+ + YSC + +
Sbjct: 195 PGGPGAGK--------RLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKD 246
Query: 121 CEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGP 180
C + KR+R CQ CR+ KCL GM +E V+ +R RG + G
Sbjct: 247 CTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQRGKDKD------------------GD 288
Query: 181 LAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPA----VATLCDLFDREI 236
AGG + PV+ ++ L VE + + P G G + V +C D+++
Sbjct: 289 GEGAGGAPE-EMPVDRILEAELAVEQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQL 347
Query: 237 VVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEG 296
+ WAK IP FSSL L DQ+ +L++ W E+L+ + RS+ ++D + A L +
Sbjct: 348 FTLVEWAKRIPHFSSLPLDDQVILLRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNS 407
Query: 297 ARAAGLGEL-GAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREAL 355
A +AG+G + L +LV +++ +R+++ E L+A+ L N D+ + + VE LRE +
Sbjct: 408 AHSAGVGAIFDRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKV 467
Query: 356 HEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFL 415
+ +L Y + G R +LLL LP LR K L H + KL G P+ +
Sbjct: 468 YASLETYCKQKYPEQQG----RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLM 523
Query: 416 EMLEA 420
EMLEA
Sbjct: 524 EMLEA 528
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 201 bits (511), Expect = 1e-51
Identities = 131/406 (32%), Positives = 202/406 (49%), Gaps = 46/406 (11%)
Query: 18 ASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKR 77
+SP +P SSE + +PP+ L +G P G ++S K
Sbjct: 95 SSPMNPVSSSE-DIKPPLGL-----------------NGVLKVPAHPSGN---MASFTKH 133
Query: 78 LCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFT 137
+C +CGD +SG HYGV SCE CK FFKRT++ + Y+C + +C I KR+R CQ CR+
Sbjct: 134 ICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQ 193
Query: 138 KCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNAL 197
KCL +GM +E V+ +R RG K + EV+ + PV +
Sbjct: 194 KCLAMGMKREAVQEERQRG---KDRNENEVE---------------STSSANEDMPVERI 235
Query: 198 VSHLLVVEPEKLYAMPDPAG--PDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLS 255
+ L VEP+ + G P V +C D+++ + WAK IP FS L L
Sbjct: 236 LEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLD 295
Query: 256 DQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGEL-GAALLQLVR 314
DQ+ +L++ W E+L+ + RS+ ++D + A L + A +AG+G + L +LV
Sbjct: 296 DQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVS 355
Query: 315 RLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAE 374
+++ +++++ E L+A+ L N DS + + VE LRE ++ +L Y + G
Sbjct: 356 KMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPG-- 413
Query: 375 RRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLEA 420
R +LLL LP LR K L H + KL G P+ +EMLEA
Sbjct: 414 --RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 457
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 196 bits (499), Expect = 3e-50
Identities = 120/348 (34%), Positives = 183/348 (52%), Gaps = 24/348 (6%)
Query: 73 SLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQ 132
SL K +C +CGD +SG HYGV SCE CK FFKRTI+ + Y+C + +C I KR+R CQ
Sbjct: 133 SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQ 192
Query: 133 ACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAA 192
CR+ KCL +GM +E V+ + RQ+ + R E + A +G
Sbjct: 193 YCRYQKCLVMGMKREAVQEE-----RQRSRERAESE----------AECATSG---HEDM 234
Query: 193 PVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSL 252
PV ++ L VEP K + D + V +C D+++ + WAK IP FS L
Sbjct: 235 PVERILEAELAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDL 293
Query: 253 SLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGEL-GAALLQ 311
+L DQ+ +L++ W E+L+ + RS+ +QD + A L + A +AG+G + L +
Sbjct: 294 TLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTE 353
Query: 312 LVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGG 371
LV +++ +++++ E L+A+ L N D+ + + VE LRE ++ L Y +
Sbjct: 354 LVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQP 413
Query: 372 GAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEMLE 419
G R +LLL LP LR K L H + KL G P+ +EMLE
Sbjct: 414 G----RFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
>gi|20070199 nuclear receptor subfamily 2, group F, member 6 [Homo
sapiens]
Length = 404
Score = 189 bits (479), Expect = 5e-48
Identities = 118/344 (34%), Positives = 175/344 (50%), Gaps = 13/344 (3%)
Query: 79 CLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTK 138
C+VCGD +SG HYGV +CE CK+FFKR+I+ ++ Y+C ++ +C+I + R CQ CR K
Sbjct: 56 CVVCGDKSSGKHYGVFTCEGCKSFFKRSIRRNLSYTCRSNRDCQIDQHHRNQCQYCRLKK 115
Query: 139 CLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALV 198
C RVGM KE V+ R+ P P A +GG PV+ L+
Sbjct: 116 CFRVGMRKEAVQRGRIPHSLPGAVAASSGSP-----PGSALAAVASGGDLFPGQPVSELI 170
Query: 199 SHLLVVEPEKLYA--MPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSD 256
+ LL EP A G G + + +C+L R + T+ WA+ P F L ++D
Sbjct: 171 AQLLRAEPYPAAAGRFGAGGGAAGAVLGIDNVCELAARLLFSTVEWARHAPFFPELPVAD 230
Query: 257 QMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQLVR 314
Q+++L+ W E+ VL AQ +LPL LA A RA + A + V
Sbjct: 231 QVALLRLSWSELFVLNAAQAALPLHTAPLLAAAGLHAAPMAAERAVAFMDQVRAFQEQVD 290
Query: 315 RLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAE 374
+L L+++ EY LKA+AL D+ + D VE L+E AL EY + ++
Sbjct: 291 KLGRLQVDSAEYGCLKAIALFTPDACGLSDPAHVESLQEKAQVALTEYVRAQY----PSQ 346
Query: 375 RRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEML 418
+R GRLLL LP LR +++ + ++L GK P+ L +ML
Sbjct: 347 PQRFGRLLLRLPALRAVPASLISQLFFMRLVGKTPIETLIRDML 390
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 185 bits (470), Expect = 6e-47
Identities = 132/418 (31%), Positives = 194/418 (46%), Gaps = 34/418 (8%)
Query: 4 QVVGIEPLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGE 63
+V G + P P P G+ T P P P + G G+G GPG
Sbjct: 14 EVPGSQGSQASQAPPVPGPPPGAPHTPQTPGQG-GPASTPAQTAAG------GQG-GPGG 65
Query: 64 QGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEI 123
G K + C+VCGD +SG HYG +CE CK+FFKR+++ ++ Y+C A+ C I
Sbjct: 66 PGSDKQQQQQHIE--CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPI 123
Query: 124 TKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAV 183
+ R CQ CR KCL+VGM +E V+ RG R P P G A+
Sbjct: 124 DQHHRNQCQYCRLKKCLKVGMRREAVQ----RG------RMPPTQP-------THGQFAL 166
Query: 184 AGG-PRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISW 242
G P + ++ +S LL EP ++ + +C+L R + + W
Sbjct: 167 TNGDPLNCHSYLSGYISLLLRAEPYPTSRFGSQCMQPNNIMGIENICELAARMLFSAVEW 226
Query: 243 AKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQ--DELAFAEDLVLDEEGARAA 300
A++IP F L ++DQ+++L+ W E+ VL AQ S+PL LA A R
Sbjct: 227 ARNIPFFPDLQITDQVALLRLTWSELFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVV 286
Query: 301 GLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALL 360
+ + V +L+AL ++ EY LKA+ L SD+ + D VE L+E AL
Sbjct: 287 AFMDHIRIFQEQVEKLKALHVDSAEYSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALE 346
Query: 361 EYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVPMHKLFLEML 418
EY + + R G+LLL LP LR + V+ + V+L GK P+ L +ML
Sbjct: 347 EYVRSQY----PNQPTRFGKLLLRLPSLRTVSSSVIEQLFFVRLVGKTPIETLIRDML 400
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 182 bits (461), Expect = 7e-46
Identities = 126/389 (32%), Positives = 184/389 (47%), Gaps = 33/389 (8%)
Query: 33 PPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYG 92
P PG PG ++ G G G G+ S C+VCGD +SG HYG
Sbjct: 49 PHTPQTPGQPGAPATPGTAGDK-----GQGPPGSGQ----SQQHIECVVCGDKSSGKHYG 99
Query: 93 VASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLD 152
+CE CK+FFKR+++ ++ Y+C A+ C I + R CQ CR KCL+VGM +E V+
Sbjct: 100 QFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKKCLKVGMRREAVQ-- 157
Query: 153 RVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGG-PRKTAAPVNALVSHLLVVEPEKLYA 211
RG R P P P G A+ G P ++ +S LL EP
Sbjct: 158 --RG------RMPPTQPNP-------GQYALTNGDPLNGHCYLSGYISLLLRAEPYPTSR 202
Query: 212 MPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVL 271
++ + +C+L R + + WA++IP F L ++DQ+S+L+ W E+ VL
Sbjct: 203 YGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSELFVL 262
Query: 272 GVAQRSLPLQ--DELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLL 329
AQ S+PL LA A R + + V +L+AL ++ EY L
Sbjct: 263 NAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAEYSCL 322
Query: 330 KALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLR 389
KA+ L SD+ + DA +E L+E AL EY + + R G+LLL LP LR
Sbjct: 323 KAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQY----PNQPSRFGKLLLRLPSLR 378
Query: 390 QTAGKVLAHFYGVKLEGKVPMHKLFLEML 418
+ V+ + V+L GK P+ L +ML
Sbjct: 379 TVSSSVIEQLFFVRLVGKTPIETLIRDML 407
>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 175 bits (443), Expect = 8e-44
Identities = 138/433 (31%), Positives = 199/433 (45%), Gaps = 45/433 (10%)
Query: 17 PASPDSPKGSSETETEPPVALAPGPA--PTRCLPGHKEEEDGEG--------------AG 60
P + P+ + PP +P A P + P + GEG
Sbjct: 178 PKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTS 237
Query: 61 PGEQGGGKL--------VLSSLP---KRLCLVCGDVASGYHYGVASCEACKAFFKRTIQG 109
P +G G L S P + C VCGD AS HYGV +CE CK FFKRT+Q
Sbjct: 238 PHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQK 297
Query: 110 SIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDP 169
+ +Y C A+ +C + KRRR CQ CRF KCL VGM+KE VR D ++G R + +P+
Sbjct: 298 NAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP- 356
Query: 170 LPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLC 229
P PA L + P A + + E + + AG V
Sbjct: 357 ---PDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGD------VQQFY 407
Query: 230 DLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAED 289
DL + V WA+ IPGF+ LS +DQ +L+S ++E+ +L +A RS P + +L F
Sbjct: 408 DLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSG 467
Query: 290 LVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVE 349
LVL A G G+ ++L R L +L ++ + L AL L +D +++ VE
Sbjct: 468 LVLHRLQC-ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI-TDRHGLQEPRRVE 525
Query: 350 QLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVP 409
+L+ + L E+ A AG A RLL LP LR + L + +KLE VP
Sbjct: 526 ELQNRIASCLKEHVAAVAGEPQPAS--CLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583
Query: 410 ----MHKLFLEML 418
+ K+F++ L
Sbjct: 584 PPPIIDKIFMDTL 596
>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 175 bits (443), Expect = 8e-44
Identities = 138/433 (31%), Positives = 199/433 (45%), Gaps = 45/433 (10%)
Query: 17 PASPDSPKGSSETETEPPVALAPGPA--PTRCLPGHKEEEDGEG--------------AG 60
P + P+ + PP +P A P + P + GEG
Sbjct: 178 PKASGPPQPPAFFSFSPPTGPSPSLAQSPLKLFPSQATHQLGEGESYSMPTAFPGLAPTS 237
Query: 61 PGEQGGGKL--------VLSSLP---KRLCLVCGDVASGYHYGVASCEACKAFFKRTIQG 109
P +G G L S P + C VCGD AS HYGV +CE CK FFKRT+Q
Sbjct: 238 PHLEGSGILDTPVTSTKARSGAPGGSEGRCAVCGDNASCQHYGVRTCEGCKGFFKRTVQK 297
Query: 110 SIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDP 169
+ +Y C A+ +C + KRRR CQ CRF KCL VGM+KE VR D ++G R + +P+
Sbjct: 298 NAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKQP- 356
Query: 170 LPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLC 229
P PA L + P A + + E + + AG V
Sbjct: 357 ---PDASPANLLTSLVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGD------VQQFY 407
Query: 230 DLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAED 289
DL + V WA+ IPGF+ LS +DQ +L+S ++E+ +L +A RS P + +L F
Sbjct: 408 DLLSGSLEVIRKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSG 467
Query: 290 LVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVE 349
LVL A G G+ ++L R L +L ++ + L AL L +D +++ VE
Sbjct: 468 LVLHRLQC-ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI-TDRHGLQEPRRVE 525
Query: 350 QLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVP 409
+L+ + L E+ A AG A RLL LP LR + L + +KLE VP
Sbjct: 526 ELQNRIASCLKEHVAAVAGEPQPAS--CLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583
Query: 410 ----MHKLFLEML 418
+ K+F++ L
Sbjct: 584 PPPIIDKIFMDTL 596
>gi|110611914 progesterone receptor [Homo sapiens]
Length = 933
Score = 171 bits (434), Expect = 9e-43
Identities = 95/289 (32%), Positives = 157/289 (54%), Gaps = 14/289 (4%)
Query: 73 SLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQ 132
SLP+++CL+CGD ASG HYGV +C +CK FFKR ++G Y C N+C + K RRK C
Sbjct: 561 SLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCP 620
Query: 133 ACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAA 192
ACR KC + GM+ G + + K + +D + P P + A R T +
Sbjct: 621 ACRLRKCCQAGMVLGGRKFKKF----NKVRVVRALDAVALPQPVGVPNESQALSQRFTFS 676
Query: 193 P------VNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSI 246
P + L++ L+ +EP+ +YA D PD + +L L +R+++ + W+KS+
Sbjct: 677 PGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSL 736
Query: 247 PGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLP--LQDELAFAEDLVLDEEGARAAGLGE 304
PGF +L + DQ++++Q WM ++V G+ RS L FA DL+L+E+ + +
Sbjct: 737 PGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYS 796
Query: 305 LGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIEDAEAVEQLRE 353
L + Q+ + L++ +EE++ +K L L N ++ +E + Q E
Sbjct: 797 LCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLN--TIPLEGLRSQTQFEE 843
>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
sapiens]
Length = 598
Score = 171 bits (432), Expect = 2e-42
Identities = 111/345 (32%), Positives = 176/345 (51%), Gaps = 14/345 (4%)
Query: 78 LCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQACRFT 137
LC VCGD A+ HYGV +CE CK FFKRT+Q + +Y C A+ C + KRRR CQ CRF
Sbjct: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
Query: 138 KCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNAL 197
KCL VGM+KE VR D ++G R + +P+ P P P+ P+++ + N
Sbjct: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSP---PSPPVSLISALVRAHVDSNPA 378
Query: 198 VSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSLSDQ 257
++ L + + A PD + DL + + WA+ IPGF+ L +DQ
Sbjct: 379 MTSL---DYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQ 435
Query: 258 MSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLDEEGARAAGLGELGAALLQLVRRLQ 317
+ +S ++E+ VL +A RS P++ +L F +VL G GE ++++ LQ
Sbjct: 436 DLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIVEFSSNLQ 494
Query: 318 ALRLEREEYVLLKALALANSDSVHIEDAEAVEQLREALHEALLEYEAGRAGPGGGAERRR 377
+ ++ + + ALA+ ++ +++ + VE+L+ + L ++ GG
Sbjct: 495 NMNIDISAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVT--FNNGGLNRPNY 551
Query: 378 AGRLLLTLPLLRQTAGKVLAHFYGVKLEGKVP----MHKLFLEML 418
+LL LP LR + L + +KLE VP + KLFL+ L
Sbjct: 552 LSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 596
>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
beta [Homo sapiens]
Length = 742
Score = 167 bits (424), Expect = 1e-41
Identities = 100/265 (37%), Positives = 141/265 (53%), Gaps = 9/265 (3%)
Query: 75 PKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQAC 134
P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N+C I K RRK C AC
Sbjct: 417 PPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 476
Query: 135 RFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPV 194
R+ KCL+ GM E + + G Q+ + PG P + P+ T
Sbjct: 477 RYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATL---PQLTP--- 530
Query: 195 NALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSL 254
LVS L V+EPE LYA D + PD + TL L R+++ + WAK+IPGF +L L
Sbjct: 531 -TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 255 SDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQL 312
DQM++LQ WM ++ + RS L FA DL+++E+ + + +L +
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 313 VRRLQALRLEREEYVLLKALALANS 337
L L++ EEY+ +K L L +S
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 167 bits (424), Expect = 1e-41
Identities = 100/265 (37%), Positives = 141/265 (53%), Gaps = 9/265 (3%)
Query: 75 PKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQAC 134
P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N+C I K RRK C AC
Sbjct: 417 PPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 476
Query: 135 RFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPV 194
R+ KCL+ GM E + + G Q+ + PG P + P+ T
Sbjct: 477 RYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATL---PQLTP--- 530
Query: 195 NALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSL 254
LVS L V+EPE LYA D + PD + TL L R+++ + WAK+IPGF +L L
Sbjct: 531 -TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 255 SDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQL 312
DQM++LQ WM ++ + RS L FA DL+++E+ + + +L +
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 313 VRRLQALRLEREEYVLLKALALANS 337
L L++ EEY+ +K L L +S
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 167 bits (424), Expect = 1e-41
Identities = 100/265 (37%), Positives = 141/265 (53%), Gaps = 9/265 (3%)
Query: 75 PKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQAC 134
P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N+C I K RRK C AC
Sbjct: 417 PPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 476
Query: 135 RFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPV 194
R+ KCL+ GM E + + G Q+ + PG P + P+ T
Sbjct: 477 RYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATL---PQLTP--- 530
Query: 195 NALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSL 254
LVS L V+EPE LYA D + PD + TL L R+++ + WAK+IPGF +L L
Sbjct: 531 -TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 255 SDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQL 312
DQM++LQ WM ++ + RS L FA DL+++E+ + + +L +
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 313 VRRLQALRLEREEYVLLKALALANS 337
L L++ EEY+ +K L L +S
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 167 bits (424), Expect = 1e-41
Identities = 100/265 (37%), Positives = 141/265 (53%), Gaps = 9/265 (3%)
Query: 75 PKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQAC 134
P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N+C I K RRK C AC
Sbjct: 417 PPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 476
Query: 135 RFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPV 194
R+ KCL+ GM E + + G Q+ + PG P + P+ T
Sbjct: 477 RYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATL---PQLTP--- 530
Query: 195 NALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSL 254
LVS L V+EPE LYA D + PD + TL L R+++ + WAK+IPGF +L L
Sbjct: 531 -TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 255 SDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQL 312
DQM++LQ WM ++ + RS L FA DL+++E+ + + +L +
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 313 VRRLQALRLEREEYVLLKALALANS 337
L L++ EEY+ +K L L +S
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 167 bits (424), Expect = 1e-41
Identities = 100/265 (37%), Positives = 141/265 (53%), Gaps = 9/265 (3%)
Query: 75 PKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQAC 134
P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N+C I K RRK C AC
Sbjct: 417 PPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 476
Query: 135 RFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPV 194
R+ KCL+ GM E + + G Q+ + PG P + P+ T
Sbjct: 477 RYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATL---PQLTP--- 530
Query: 195 NALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSL 254
LVS L V+EPE LYA D + PD + TL L R+++ + WAK+IPGF +L L
Sbjct: 531 -TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 255 SDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQL 312
DQM++LQ WM ++ + RS L FA DL+++E+ + + +L +
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 313 VRRLQALRLEREEYVLLKALALANS 337
L L++ EEY+ +K L L +S
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 167 bits (424), Expect = 1e-41
Identities = 100/265 (37%), Positives = 141/265 (53%), Gaps = 9/265 (3%)
Query: 75 PKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKACQAC 134
P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N+C I K RRK C AC
Sbjct: 417 PPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNCPAC 476
Query: 135 RFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFPAGPLAVAGGPRKTAAPV 194
R+ KCL+ GM E + + G Q+ + PG P + P+ T
Sbjct: 477 RYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIVPATL---PQLTP--- 530
Query: 195 NALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREIVVTISWAKSIPGFSSLSL 254
LVS L V+EPE LYA D + PD + TL L R+++ + WAK+IPGF +L L
Sbjct: 531 -TLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAIPGFRNLHL 589
Query: 255 SDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDLVLDEEGARAAGLGELGAALLQL 312
DQM++LQ WM ++ + RS L FA DL+++E+ + + +L +
Sbjct: 590 DDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYDQCKHMLYV 649
Query: 313 VRRLQALRLEREEYVLLKALALANS 337
L L++ EEY+ +K L L +S
Sbjct: 650 SSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Homo
sapiens]
Length = 984
Score = 165 bits (418), Expect = 6e-41
Identities = 101/287 (35%), Positives = 153/287 (53%), Gaps = 23/287 (8%)
Query: 72 SSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRKAC 131
SS P ++CLVCGD ASG HYGV +C +CK FFKR ++G Y C N+C I K RRK C
Sbjct: 596 SSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDKIRRKNC 655
Query: 132 QACRFTKCLRVGM---LKEGVRLDRVRGGRQKYKRRPEVDPLPFPGPFP-AGPLAVAGGP 187
ACR KCL+ GM ++ +L +++G ++ ++ + P P P P G +A P
Sbjct: 656 PACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSPEEGTTYIA--P 713
Query: 188 RKTAAPVNALVSHLLV---------------VEPEKLYAMPDPAGPDGHLPAVATLCDLF 232
K + ALV L +EPE +YA D + PD ++TL L
Sbjct: 714 AKEPSVNTALVPQLSTISRALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLA 773
Query: 233 DREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDE--LAFAEDL 290
++++ + WAK +PGF +L L DQ++++Q WM + ++ RS + L FA DL
Sbjct: 774 GKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSWRSYKHTNSQFLYFAPDL 833
Query: 291 VLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANS 337
V +EE + + EL + Q+ + L+L EEY ++K L L ++
Sbjct: 834 VFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLST 880
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,084,690
Number of Sequences: 37866
Number of extensions: 1092405
Number of successful extensions: 6567
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 6062
Number of HSP's gapped (non-prelim): 442
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.