Search of human proteins with 18860841

Search of human proteins with 18860841

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
         (979 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]                 1953   0.0  
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]                1935   0.0  
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]                1910   0.0  
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]                 1910   0.0  
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]                 1865   0.0  
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]                1847   0.0  
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]                1821   0.0  
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]                 1821   0.0  
gi|56549125 dynamin 2 isoform 4 [Homo sapiens]                        114   4e-25
gi|56549123 dynamin 2 isoform 2 [Homo sapiens]                        114   4e-25
gi|56549121 dynamin 2 isoform 1 [Homo sapiens]                        114   4e-25
gi|56549119 dynamin 2 isoform 3 [Homo sapiens]                        114   4e-25
gi|56549117 dynamin 1 isoform 2 [Homo sapiens]                        107   5e-23
gi|59853099 dynamin 1 isoform 1 [Homo sapiens]                        107   5e-23
gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]                  104   4e-22
gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]                  104   4e-22
gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]                  104   4e-22
gi|42544243 dynamin 3 isoform a [Homo sapiens]                        103   8e-22
gi|209915561 dynamin 3 isoform b [Homo sapiens]                       103   8e-22
gi|222136619 myxovirus resistance protein 1 [Homo sapiens]            102   2e-21
gi|222136617 myxovirus resistance protein 1 [Homo sapiens]            102   2e-21
gi|11342664 myxovirus resistance protein 2 [Homo sapiens]              99   3e-20
gi|116235456 ring finger protein 214 [Homo sapiens]                    42   0.004
gi|116235451 ring finger protein 214 [Homo sapiens]                    42   0.004
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    41   0.006
gi|224593756 hypothetical protein LOC164127 [Homo sapiens]             40   0.011
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     39   0.018
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo...    39   0.024
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo...    39   0.024
gi|28173564 keratin 73 [Homo sapiens]                                  39   0.031

>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
          Length = 979

 Score = 1953 bits (5060), Expect = 0.0
 Identities = 979/979 (100%), Positives = 979/979 (100%)

Query: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
           MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60

Query: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
           QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120

Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR 180
           QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR 180

Query: 181 GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE 240
           GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE
Sbjct: 181 GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE 240

Query: 241 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 300
           LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS
Sbjct: 241 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 300

Query: 301 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 360
           YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF
Sbjct: 301 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 360

Query: 361 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 420
           KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG
Sbjct: 361 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 420

Query: 421 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 480
           VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR
Sbjct: 421 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 480

Query: 481 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 540
           TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE
Sbjct: 481 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 540

Query: 541 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 600
           FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN
Sbjct: 541 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 600

Query: 601 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 660
           YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA
Sbjct: 601 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 660

Query: 661 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 720
           QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK
Sbjct: 661 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 720

Query: 721 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 780
           EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN
Sbjct: 721 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 780

Query: 781 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 840
           AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL
Sbjct: 781 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 840

Query: 841 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 900
           ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW
Sbjct: 841 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 900

Query: 901 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 960
           RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK
Sbjct: 901 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 960

Query: 961 VREIQEKLDAFIEALHQEK 979
           VREIQEKLDAFIEALHQEK
Sbjct: 961 VREIQEKLDAFIEALHQEK 979


>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
          Length = 1015

 Score = 1935 bits (5013), Expect = 0.0
 Identities = 979/1015 (96%), Positives = 979/1015 (96%), Gaps = 36/1015 (3%)

Query: 1    MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
            MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1    MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60

Query: 61   QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
            QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61   QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120

Query: 121  QWKDMIPDLSEYKWIVPDIVWEIDEYIDF------------------------------- 149
            QWKDMIPDLSEYKWIVPDIVWEIDEYIDF                               
Sbjct: 121  QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180

Query: 150  -----GHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 204
                 GHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ
Sbjct: 181  DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 240

Query: 205  EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 264
            EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK
Sbjct: 241  EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 300

Query: 265  LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 324
            LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL
Sbjct: 301  LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 360

Query: 325  EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 384
            EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL
Sbjct: 361  EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 420

Query: 385  RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 444
            RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY
Sbjct: 421  RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 480

Query: 445  MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 504
            MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI
Sbjct: 481  MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 540

Query: 505  IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 564
            IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS
Sbjct: 541  IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 600

Query: 565  LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 624
            LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV
Sbjct: 601  LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 660

Query: 625  ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 684
            ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL
Sbjct: 661  ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 720

Query: 685  PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 744
            PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI
Sbjct: 721  PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 780

Query: 745  QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 804
            QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ
Sbjct: 781  QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 840

Query: 805  CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 864
            CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF
Sbjct: 841  CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 900

Query: 865  LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 924
            LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR
Sbjct: 901  LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 960

Query: 925  LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 979
            LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 961  LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 1015


>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
          Length = 997

 Score = 1910 bits (4948), Expect = 0.0
 Identities = 965/998 (96%), Positives = 969/998 (97%), Gaps = 20/998 (2%)

Query: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
           MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60

Query: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
           QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120

Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLL------------- 167
           QWKDMIPDLSEYKWIVPDIVWEIDEYIDF  K+   +  + DL+ L              
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF-EKIRKALPSSEDLVKLAPDFDKIVESLSLL 179

Query: 168 ------GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSY 221
                 GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSY
Sbjct: 180 KDFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSY 239

Query: 222 AQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK 281
           AQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK
Sbjct: 240 AQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK 299

Query: 282 SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM 341
           SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM
Sbjct: 300 SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM 359

Query: 342 TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI 401
           TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI
Sbjct: 360 TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI 419

Query: 402 SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD 461
           SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD
Sbjct: 420 SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD 479

Query: 462 AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV 521
           AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV
Sbjct: 480 AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV 539

Query: 522 TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ 581
           TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ
Sbjct: 540 TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ 599

Query: 582 QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ 641
           QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ
Sbjct: 600 QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ 659

Query: 642 SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS 701
           SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS
Sbjct: 660 SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS 719

Query: 702 RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD 761
           RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD
Sbjct: 720 RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD 779

Query: 762 AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN 821
           AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN
Sbjct: 780 AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN 839

Query: 822 EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY 881
           EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY
Sbjct: 840 EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY 899

Query: 882 YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE 941
           YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE
Sbjct: 900 YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE 959

Query: 942 KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 979
           KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 960 KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997


>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
          Length = 961

 Score = 1910 bits (4947), Expect = 0.0
 Identities = 961/979 (98%), Positives = 961/979 (98%), Gaps = 18/979 (1%)

Query: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
           MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60

Query: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
           QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120

Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR 180
           QWKDMIPDLSEYKWIVPDIVWEIDEYIDFG                  SPEETAFRATDR
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFG------------------SPEETAFRATDR 162

Query: 181 GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE 240
           GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE
Sbjct: 163 GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE 222

Query: 241 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 300
           LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS
Sbjct: 223 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 282

Query: 301 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 360
           YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF
Sbjct: 283 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 342

Query: 361 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 420
           KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG
Sbjct: 343 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 402

Query: 421 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 480
           VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR
Sbjct: 403 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 462

Query: 481 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 540
           TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE
Sbjct: 463 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 522

Query: 541 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 600
           FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN
Sbjct: 523 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 582

Query: 601 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 660
           YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA
Sbjct: 583 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 642

Query: 661 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 720
           QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK
Sbjct: 643 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 702

Query: 721 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 780
           EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN
Sbjct: 703 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 762

Query: 781 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 840
           AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL
Sbjct: 763 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 822

Query: 841 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 900
           ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW
Sbjct: 823 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 882

Query: 901 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 960
           RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK
Sbjct: 883 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 942

Query: 961 VREIQEKLDAFIEALHQEK 979
           VREIQEKLDAFIEALHQEK
Sbjct: 943 VREIQEKLDAFIEALHQEK 961


>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
          Length = 942

 Score = 1865 bits (4830), Expect = 0.0
 Identities = 942/979 (96%), Positives = 942/979 (96%), Gaps = 37/979 (3%)

Query: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
           MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60

Query: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
           QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120

Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR 180
           QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR 180

Query: 181 GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE 240
           GSESDKHF                                     RKVSDKEKIDQLQEE
Sbjct: 181 GSESDKHF-------------------------------------RKVSDKEKIDQLQEE 203

Query: 241 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 300
           LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS
Sbjct: 204 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 263

Query: 301 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 360
           YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF
Sbjct: 264 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 323

Query: 361 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 420
           KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG
Sbjct: 324 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 383

Query: 421 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 480
           VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR
Sbjct: 384 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 443

Query: 481 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 540
           TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE
Sbjct: 444 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 503

Query: 541 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 600
           FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN
Sbjct: 504 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 563

Query: 601 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 660
           YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA
Sbjct: 564 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 623

Query: 661 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 720
           QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK
Sbjct: 624 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 683

Query: 721 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 780
           EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN
Sbjct: 684 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 743

Query: 781 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 840
           AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL
Sbjct: 744 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 803

Query: 841 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 900
           ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW
Sbjct: 804 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 863

Query: 901 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 960
           RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK
Sbjct: 864 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 923

Query: 961 VREIQEKLDAFIEALHQEK 979
           VREIQEKLDAFIEALHQEK
Sbjct: 924 VREIQEKLDAFIEALHQEK 942


>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
          Length = 978

 Score = 1847 bits (4783), Expect = 0.0
 Identities = 942/1015 (92%), Positives = 942/1015 (92%), Gaps = 73/1015 (7%)

Query: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
           MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60

Query: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
           QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120

Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF------------------------------- 149
           QWKDMIPDLSEYKWIVPDIVWEIDEYIDF                               
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180

Query: 150 -----GHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 204
                GHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFR               
Sbjct: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFR--------------- 225

Query: 205 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 264
                                 KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK
Sbjct: 226 ----------------------KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 263

Query: 265 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 324
           LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL
Sbjct: 264 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 323

Query: 325 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 384
           EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL
Sbjct: 324 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 383

Query: 385 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 444
           RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY
Sbjct: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443

Query: 445 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 504
           MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI
Sbjct: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503

Query: 505 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 564
           IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS
Sbjct: 504 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 563

Query: 565 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 624
           LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV
Sbjct: 564 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 623

Query: 625 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 684
           ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL
Sbjct: 624 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 683

Query: 685 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 744
           PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI
Sbjct: 684 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 743

Query: 745 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 804
           QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ
Sbjct: 744 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 803

Query: 805 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 864
           CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF
Sbjct: 804 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 863

Query: 865 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 924
           LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR
Sbjct: 864 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 923

Query: 925 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 979
           LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 924 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 978


>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
          Length = 960

 Score = 1821 bits (4718), Expect = 0.0
 Identities = 928/998 (92%), Positives = 932/998 (93%), Gaps = 57/998 (5%)

Query: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
           MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60

Query: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
           QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120

Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLL------------- 167
           QWKDMIPDLSEYKWIVPDIVWEIDEYIDF  K+   +  + DL+ L              
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF-EKIRKALPSSEDLVKLAPDFDKIVESLSLL 179

Query: 168 ------GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSY 221
                 GSPEETAFRATDRGSESDKHFR                                
Sbjct: 180 KDFFTSGSPEETAFRATDRGSESDKHFR-------------------------------- 207

Query: 222 AQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK 281
                KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK
Sbjct: 208 -----KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKK 262

Query: 282 SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM 341
           SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM
Sbjct: 263 SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMM 322

Query: 342 TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI 401
           TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI
Sbjct: 323 TRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETI 382

Query: 402 SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD 461
           SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD
Sbjct: 383 SLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVD 442

Query: 462 AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV 521
           AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV
Sbjct: 443 AERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVV 502

Query: 522 TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ 581
           TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ
Sbjct: 503 TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ 562

Query: 582 QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ 641
           QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ
Sbjct: 563 QADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQ 622

Query: 642 SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS 701
           SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS
Sbjct: 623 SLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFS 682

Query: 702 RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD 761
           RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD
Sbjct: 683 RFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWD 742

Query: 762 AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN 821
           AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN
Sbjct: 743 AAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCN 802

Query: 822 EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY 881
           EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY
Sbjct: 803 EEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYY 862

Query: 882 YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE 941
           YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE
Sbjct: 863 YQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGE 922

Query: 942 KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 979
           KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 923 KKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 960


>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
          Length = 924

 Score = 1821 bits (4717), Expect = 0.0
 Identities = 924/979 (94%), Positives = 924/979 (94%), Gaps = 55/979 (5%)

Query: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
           MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1   MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60

Query: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
           QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61  QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120

Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR 180
           QWKDMIPDLSEYKWIVPDIVWEIDEYIDF                  GSPEETAFRATDR
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF------------------GSPEETAFRATDR 162

Query: 181 GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE 240
           GSESDKHF                                     RKVSDKEKIDQLQEE
Sbjct: 163 GSESDKHF-------------------------------------RKVSDKEKIDQLQEE 185

Query: 241 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 300
           LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS
Sbjct: 186 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 245

Query: 301 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 360
           YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF
Sbjct: 246 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 305

Query: 361 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 420
           KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG
Sbjct: 306 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 365

Query: 421 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 480
           VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR
Sbjct: 366 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 425

Query: 481 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 540
           TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE
Sbjct: 426 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 485

Query: 541 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 600
           FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN
Sbjct: 486 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 545

Query: 601 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 660
           YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA
Sbjct: 546 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 605

Query: 661 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 720
           QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK
Sbjct: 606 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 665

Query: 721 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 780
           EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN
Sbjct: 666 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 725

Query: 781 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 840
           AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL
Sbjct: 726 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 785

Query: 841 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 900
           ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW
Sbjct: 786 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 845

Query: 901 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 960
           RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK
Sbjct: 846 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 905

Query: 961 VREIQEKLDAFIEALHQEK 979
           VREIQEKLDAFIEALHQEK
Sbjct: 906 VREIQEKLDAFIEALHQEK 924


>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
          Length = 866

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64

Query: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119

Query: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179

Query: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234

Query: 521 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291

Query: 578 SVEQQADSFKATRFNLE---TEWKNNYP 602
           S+       ++   +LE    E+KN  P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319


>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
          Length = 870

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64

Query: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119

Query: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179

Query: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234

Query: 521 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291

Query: 578 SVEQQADSFKATRFNLE---TEWKNNYP 602
           S+       ++   +LE    E+KN  P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319


>gi|56549121 dynamin 2 isoform 1 [Homo sapiens]
          Length = 870

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64

Query: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119

Query: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179

Query: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234

Query: 521 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291

Query: 578 SVEQQADSFKATRFNLE---TEWKNNYP 602
           S+       ++   +LE    E+KN  P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319


>gi|56549119 dynamin 2 isoform 3 [Homo sapiens]
          Length = 866

 Score =  114 bits (285), Expect = 4e-25
 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           + LI + +++ D  S    S +    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 7   EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64

Query: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
             R  +   +     H       S++F      D   +R EIE    +       +SP  
Sbjct: 65  TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119

Query: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   +++IL +   ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179

Query: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234

Query: 521 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577
           V       E    I A    E +FF +    +     A ++ T +L   ++      +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291

Query: 578 SVEQQADSFKATRFNLE---TEWKNNYP 602
           S+       ++   +LE    E+KN  P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319


>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
          Length = 851

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63

Query: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119

Query: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179

Query: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234

Query: 521 VTGKG---NSSESIEAIREYEEEFF 542
           V       +  + I A    E +FF
Sbjct: 235 VNRSQKDIDGKKDITAALAAERKFF 259


>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
          Length = 864

 Score =  107 bits (267), Expect = 5e-23
 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           + LI + + + D  S      N    LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 7   EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63

Query: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
           +TR P+ + L       A F     +    K  D   +R EIE    +       +SP  
Sbjct: 64  VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119

Query: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
           I+L V  P +  + LVDLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179

Query: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
           D   S    +  ++DP G+RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234

Query: 521 VTGKG---NSSESIEAIREYEEEFF 542
           V       +  + I A    E +FF
Sbjct: 235 VNRSQKDIDGKKDITAALAAERKFF 259


>gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]
          Length = 736

 Score =  104 bits (260), Expect = 4e-22
 Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           ++LI + +++ DV +   A       LP++VVVG QS+GK+SVLE +    + PRG+G +
Sbjct: 2   EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57

Query: 341 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 384
           +TR P+ + L     HV+     K +  E  +  EE             D   +R EIE 
Sbjct: 58  VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113

Query: 385 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 444
              +       VSPE I L +  P +  + LVDLPG+          D +  I  +   +
Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173

Query: 445 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 504
           + NPN+IIL +   + D   S    +  ++DP GRRT+ V+TK+DL +    +      +
Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229

Query: 505 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 543
           + G++ P+K LG   VV        N     ++IR+ E  F Q
Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270


>gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]
          Length = 699

 Score =  104 bits (260), Expect = 4e-22
 Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           ++LI + +++ DV +   A       LP++VVVG QS+GK+SVLE +    + PRG+G +
Sbjct: 2   EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57

Query: 341 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 384
           +TR P+ + L     HV+     K +  E  +  EE             D   +R EIE 
Sbjct: 58  VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113

Query: 385 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 444
              +       VSPE I L +  P +  + LVDLPG+          D +  I  +   +
Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173

Query: 445 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 504
           + NPN+IIL +   + D   S    +  ++DP GRRT+ V+TK+DL +    +      +
Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229

Query: 505 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 543
           + G++ P+K LG   VV        N     ++IR+ E  F Q
Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270


>gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
          Length = 710

 Score =  104 bits (260), Expect = 4e-22
 Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           ++LI + +++ DV +   A       LP++VVVG QS+GK+SVLE +    + PRG+G +
Sbjct: 2   EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57

Query: 341 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 384
           +TR P+ + L     HV+     K +  E  +  EE             D   +R EIE 
Sbjct: 58  VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113

Query: 385 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 444
              +       VSPE I L +  P +  + LVDLPG+          D +  I  +   +
Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173

Query: 445 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 504
           + NPN+IIL +   + D   S    +  ++DP GRRT+ V+TK+DL +    +      +
Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229

Query: 505 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 543
           + G++ P+K LG   VV        N     ++IR+ E  F Q
Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270


>gi|42544243 dynamin 3 isoform a [Homo sapiens]
          Length = 863

 Score =  103 bits (257), Expect = 8e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63

Query: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119

Query: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179

Query: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234

Query: 521 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291

Query: 578 SVEQQADSFKATRFNLETE---WKNNYP 602
           ++    +  +    ++E E   +KN  P
Sbjct: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319


>gi|209915561 dynamin 3 isoform b [Homo sapiens]
          Length = 859

 Score =  103 bits (257), Expect = 8e-22
 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)

Query: 281 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 340
           + LI + + + D  S    S   +  LP++ VVG QSAGK+SVLE        PRGSG +
Sbjct: 7   EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63

Query: 341 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 400
           +TR P+ + L       A F     +    K  D   +R EIE    +       +S   
Sbjct: 64  VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119

Query: 401 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 460
           I+L V  P +  + L+DLPG+         PD +  I  +   ++   N +IL +   + 
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179

Query: 461 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
           D   S    L  ++DP G RTI V+TK+DL ++   +    + ++E KL P++  GY  V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234

Query: 521 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 577
           V       +  + I+A    E +FF +    +     A ++ T +L   ++      +R+
Sbjct: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291

Query: 578 SVEQQADSFKATRFNLETE---WKNNYP 602
           ++    +  +    ++E E   +KN  P
Sbjct: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319


>gi|222136619 myxovirus resistance protein 1 [Homo sapiens]
          Length = 662

 Score =  102 bits (253), Expect = 2e-21
 Identities = 113/478 (23%), Positives = 210/478 (43%), Gaps = 29/478 (6%)

Query: 266 VLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQD-HLPRVVVVGDQSAGKTSVL 324
           V QK+   +    L     +     +D++    A    QD  LP + V+GDQS+GK+SVL
Sbjct: 28  VAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVL 87

Query: 325 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF-KDSSREFDLTKEEDLAALRHEIE 383
           E ++   + PRGSG ++TR P+ + L +  +      K S +++++ +  D + +  EI 
Sbjct: 88  EALSGVAL-PRGSG-IVTRCPLVLKLKKLVNEDKWRGKVSYQDYEI-EISDASEVEKEIN 144

Query: 384 LRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKA 443
                   EG  +S E I+L +    +  + L+DLPG+          D    I ++ K 
Sbjct: 145 KAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKK 204

Query: 444 YMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQ 503
           Y+Q    I L +   +VD   +    +  ++DP G RTI +LTK DL +K   +  ++  
Sbjct: 205 YIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDK--GTEDKVVD 262

Query: 504 IIEGKLFPMKALGYFAVVTGKG----NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVT 559
           ++   +F +K  GY  +V  +G        S+    + E+ FF+N    +  +L+  + T
Sbjct: 263 VVRNLVFHLKK-GYM-IVKCRGQQEIQDQLSLSEALQREKIFFENHPYFR-DLLEEGKAT 319

Query: 560 TRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNE----LFEK 615
              L+  ++      + +S+    +  K T   +  E +     + E D NE    L +K
Sbjct: 320 VPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPE-DENEKMFFLIDK 378

Query: 616 AKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH----VIENIYLPAAQTMNSGTFNTT 671
             N    ++ +L Q      EE ++     R   H    +IEN +    + +     +  
Sbjct: 379 V-NAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKIL-----SRK 432

Query: 672 VDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIK 729
           +     Q+  ++LP       +ET+ ++  + + EP       + D ++ A  + SIK
Sbjct: 433 IQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIK 490


>gi|222136617 myxovirus resistance protein 1 [Homo sapiens]
          Length = 662

 Score =  102 bits (253), Expect = 2e-21
 Identities = 113/478 (23%), Positives = 210/478 (43%), Gaps = 29/478 (6%)

Query: 266 VLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQD-HLPRVVVVGDQSAGKTSVL 324
           V QK+   +    L     +     +D++    A    QD  LP + V+GDQS+GK+SVL
Sbjct: 28  VAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVL 87

Query: 325 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF-KDSSREFDLTKEEDLAALRHEIE 383
           E ++   + PRGSG ++TR P+ + L +  +      K S +++++ +  D + +  EI 
Sbjct: 88  EALSGVAL-PRGSG-IVTRCPLVLKLKKLVNEDKWRGKVSYQDYEI-EISDASEVEKEIN 144

Query: 384 LRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKA 443
                   EG  +S E I+L +    +  + L+DLPG+          D    I ++ K 
Sbjct: 145 KAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKK 204

Query: 444 YMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQ 503
           Y+Q    I L +   +VD   +    +  ++DP G RTI +LTK DL +K   +  ++  
Sbjct: 205 YIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDK--GTEDKVVD 262

Query: 504 IIEGKLFPMKALGYFAVVTGKG----NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVT 559
           ++   +F +K  GY  +V  +G        S+    + E+ FF+N    +  +L+  + T
Sbjct: 263 VVRNLVFHLKK-GYM-IVKCRGQQEIQDQLSLSEALQREKIFFENHPYFR-DLLEEGKAT 319

Query: 560 TRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNE----LFEK 615
              L+  ++      + +S+    +  K T   +  E +     + E D NE    L +K
Sbjct: 320 VPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPE-DENEKMFFLIDK 378

Query: 616 AKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH----VIENIYLPAAQTMNSGTFNTT 671
             N    ++ +L Q      EE ++     R   H    +IEN +    + +     +  
Sbjct: 379 V-NAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKIL-----SRK 432

Query: 672 VDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIK 729
           +     Q+  ++LP       +ET+ ++  + + EP       + D ++ A  + SIK
Sbjct: 433 IQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIK 490


>gi|11342664 myxovirus resistance protein 2 [Homo sapiens]
          Length = 715

 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 65/214 (30%), Positives = 107/214 (50%), Gaps = 6/214 (2%)

Query: 307 LPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSRE 366
           LP + V+GDQS+GK+SVLE ++   + PRGSG ++TR P+ + L + P      + S R 
Sbjct: 118 LPAIAVIGDQSSGKSSVLEALSGVAL-PRGSG-IVTRCPLVLKLKKQPCEAWAGRISYRN 175

Query: 367 FDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVT 426
            +L + +D   +  EI          G  +S E ISL +  P +  + ++DLPG+     
Sbjct: 176 TEL-ELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDLTIIDLPGITRVAV 234

Query: 427 SGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLT 486
                D    I ++ K Y+Q    I L +   +VD   +    +  ++DP G RTI +LT
Sbjct: 235 DNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHEVDPEGDRTIGILT 294

Query: 487 KVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 520
           K DL ++   +   +  ++    +P+K  GY  V
Sbjct: 295 KPDLMDR--GTEKSVMNVVRNLTYPLKK-GYMIV 325


>gi|116235456 ring finger protein 214 [Homo sapiens]
          Length = 703

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 38/171 (22%), Positives = 76/171 (44%), Gaps = 12/171 (7%)

Query: 160 ASDLLLLLGSPEETAFRATDRGSESDKHFRKGL---LGELILLQQQIQEHEEEARRAAGQ 216
           +S L L      +T F+  D    +D+   K L   + E  LL+++ QE  ++ R+   Q
Sbjct: 194 SSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQ 253

Query: 217 YSTSYAQ-QKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIH 275
                 Q Q+R+  + +   ++ + +    +K +   +++EKE KE   L  ++D K   
Sbjct: 254 LQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF--LQKEQDLKAEI 311

Query: 276 HRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEM 326
            +  +K   +++   LD L + D   N      R ++   + A K  +L +
Sbjct: 312 EKLCEKGRREVWEMELDRLKNQDGEIN------RNIMEETERAWKAEILSL 356


>gi|116235451 ring finger protein 214 [Homo sapiens]
          Length = 703

 Score = 41.6 bits (96), Expect = 0.004
 Identities = 38/171 (22%), Positives = 76/171 (44%), Gaps = 12/171 (7%)

Query: 160 ASDLLLLLGSPEETAFRATDRGSESDKHFRKGL---LGELILLQQQIQEHEEEARRAAGQ 216
           +S L L      +T F+  D    +D+   K L   + E  LL+++ QE  ++ R+   Q
Sbjct: 194 SSSLKLSQNIAVQTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQ 253

Query: 217 YSTSYAQ-QKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIH 275
                 Q Q+R+  + +   ++ + +    +K +   +++EKE KE   L  ++D K   
Sbjct: 254 LQVQLKQLQQRREEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF--LQKEQDLKAEI 311

Query: 276 HRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEM 326
            +  +K   +++   LD L + D   N      R ++   + A K  +L +
Sbjct: 312 EKLCEKGRREVWEMELDRLKNQDGEIN------RNIMEETERAWKAEILSL 356


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
           sapiens]
          Length = 2168

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 25/92 (27%), Positives = 50/92 (54%), Gaps = 7/92 (7%)

Query: 197 ILLQQQIQEHEEEARRAAGQYSTSYAQQKRK-------VSDKEKIDQLQEELLHTQLKYQ 249
           +L + Q QE    A+ A  Q +   A++KRK       +  +EKI ++Q+  +  +L+ Q
Sbjct: 903 LLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQ 962

Query: 250 RILERLEKENKELRKLVLQKDDKGIHHRKLKK 281
           +ILE  +K+ +E     L + +K I  +++++
Sbjct: 963 QILEAKKKKKEEAANAKLLEAEKRIKEKEMRR 994


>gi|224593756 hypothetical protein LOC164127 [Homo sapiens]
          Length = 623

 Score = 40.0 bits (92), Expect = 0.011
 Identities = 36/158 (22%), Positives = 75/158 (47%), Gaps = 6/158 (3%)

Query: 180 RGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSD--KEKIDQL 237
           R  E  +  RK    EL    Q+ +E  ++AR  AG+       +KR + +   EKI Q 
Sbjct: 458 RSQEIHQGLRKERQRELREKAQKEEEQLQQARWRAGESEEQRKMRKRILVELADEKIRQA 517

Query: 238 QEELLHT---QLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVL 294
           +  +  T   ++++ R L  L ++N  + KL  +K++K  H   +K+++      V  + 
Sbjct: 518 RSHVHKTTRDKVQHLRELNHLREKNHHILKLKAEKEEK-CHIEGIKEAIKKKEQRVQHIS 576

Query: 295 SDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARI 332
              D ++     LP+     +++   +S+ +M+ +A++
Sbjct: 577 QGKDPNFQEFQKLPQASRREERAPPNSSLDQMVLEAQL 614


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 39.3 bits (90), Expect = 0.018
 Identities = 145/792 (18%), Positives = 311/792 (39%), Gaps = 129/792 (16%)

Query: 230  DKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSL---IDM 286
            DK K+ +L  +L  T  ++Q +    EK NK L       +DK +  +KL + L   +D+
Sbjct: 1167 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSL-------EDKSLEFKKLSEELAIQLDI 1219

Query: 287  YSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPV 346
              +  + L +   +        +   +  + +        + +A +    +   +     
Sbjct: 1220 CCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLR 1279

Query: 347  KVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVK 406
            ++T  +   +++ F+ ++ + +  KE  + +++ +IE           ++  E  +L  +
Sbjct: 1280 QLTEEQNTLNIS-FQQATHQLE-EKENQIKSMKADIE-----------SLVTEKEALQKE 1326

Query: 407  GPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSI 466
            G   Q+                 A + +  I  + K   +N NA+ L  ++  +  ++  
Sbjct: 1327 GGNQQQA----------------ASEKESCITQLKKELSENINAVTLMKEE--LKEKKVE 1368

Query: 467  VTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGK---LFPMKALGYFAVVTG 523
            ++ L  Q+       + +   + L+EK  A  S  +Q  E K   L  ++ L  F V T 
Sbjct: 1369 ISSLSKQLTD---LNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLS-FKVDTL 1424

Query: 524  KGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVS---------DCFWKM 574
                  ++E + ++  +F +  K  + S    HQ T + L + +          D    +
Sbjct: 1425 SKEKISALEQVDDWSNKFSEWKKKAQ-SRFTQHQNTVKELQIQLELKSKEAYEKDEQINL 1483

Query: 575  VRESVEQQADSFKATR--------------FNLETEWKNNYPRLRELDRNELFEKAKNEI 620
            ++E ++QQ   F   +               NLETE K+   R+ EL+ +   +  + E 
Sbjct: 1484 LKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIES 1543

Query: 621  LDEVI-SLSQVTPKHWEEILQ-----QSLWERVSTHVIE----------NIYLPAAQTMN 664
            L+EV+ + +Q      +E++Q     Q L E     V E           +Y   A+   
Sbjct: 1544 LNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1603

Query: 665  SGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVK 724
                   V++ +K    K+   KA+E   + L+ E +  + E K K    I    K+ + 
Sbjct: 1604 KKKELEHVNLSVK---SKEEELKALE---DRLESESAAKLAELKRKAEQKIAAIKKQLLS 1657

Query: 725  EESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA-IE 783
            +   K  ++    E  L  +          +  Q+ +  ++ +EE    +LK  E++  E
Sbjct: 1658 QMEEKEEQYKKGTESHLSELN---------TKLQEREREVHILEE----KLKSVESSQSE 1704

Query: 784  NMVGPDWKKRWLYWKNRTQ---EQCV---HNETKNELEKMLKCNEEHPAYLASDEITTVR 837
             ++ P   K    +  + +   + CV   + E  + L++ L   E+    +  ++  TV 
Sbjct: 1705 TLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVS 1764

Query: 838  KNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNH----CNLCRRGFYYYQRHFVDSELEC 893
             + E R  +    LIK   H   ++H  ++ + H         + +       V+ E   
Sbjct: 1765 SHFEMR-CQYQERLIK-LEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGK 1822

Query: 894  NDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQ 953
            N++     ++ +      TL+++    ++  LE+ +KE+  D     +K++      RV+
Sbjct: 1823 NNIQAKQNLENVFDDVQKTLQEKELTCQI--LEQKIKEL--DSCLVRQKEV-----HRVE 1873

Query: 954  LAEDLKKVREIQ 965
            + E   K  ++Q
Sbjct: 1874 MEELTSKYEKLQ 1885



 Score = 38.1 bits (87), Expect = 0.041
 Identities = 35/153 (22%), Positives = 70/153 (45%), Gaps = 6/153 (3%)

Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR 180
           Q KD+  +L  +K  V D++ ++++      + V  +    +  L  G+ E+   +    
Sbjct: 848 QKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILV 907

Query: 181 GSESD-KHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQE 239
             E+     R+G   E+ +L Q++   E+       +Y T +  Q++K+   EK+ Q  +
Sbjct: 908 EKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKM---EKVKQKAK 964

Query: 240 ELLHTQLKYQRILERLEKENKELRKLVLQKDDK 272
           E+  T  K  ++L++  K  KEL    L+   K
Sbjct: 965 EMQETLKK--KLLDQEAKLKKELENTALELSQK 995



 Score = 36.6 bits (83), Expect = 0.12
 Identities = 146/761 (19%), Positives = 300/761 (39%), Gaps = 106/761 (13%)

Query: 171  EETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSD 230
            EE   +      E  K   K    E I LQQ++   ++E      + S     + +K+ +
Sbjct: 427  EEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHE 486

Query: 231  KE---KIDQLQEELLHTQLKYQRILE-RLEKENKELRKLVLQKDDK---GIHHRKLKKSL 283
            KE   K  +L ++L   + ++Q  ++  LEK   E  K+  +K+ +    +   +L+K  
Sbjct: 487  KELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKA 546

Query: 284  IDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTR 343
            I   SE  + L D      T     R  ++  +S+ + S+ E   Q++           +
Sbjct: 547  ILTESE--NKLRDLQQEAETY----RTRILELESSLEKSLQENKNQSKDLAVHLEAEKNK 600

Query: 344  SPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISL 403
               ++T+    H   L +    + D    E L  L+ + +  M K ++E C    ET+ L
Sbjct: 601  HNKEITVMVEKHKTEL-ESLKHQQDALWTEKLQVLKQQYQTEMEK-LREKCEQEKETL-L 657

Query: 404  NVKGPGLQRMV------LVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQD 457
              K    Q  +       ++   V  T    ++ +  E + +  K   +     +  ++D
Sbjct: 658  KDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEE-----LSVLKD 712

Query: 458  GSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGY 517
             +   ++ +   +  Q + H ++   ++      +++  S  R ++ ++ ++  ++ L  
Sbjct: 713  QTDKMKQELEAKMDEQKNHHQQQVDSII------KEHEVSIQRTEKALKDQINQLELLLK 766

Query: 518  FAVVTGKGNSS--ESIEA-IREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKM 574
                  K + +  E++EA I+  E E  Q S   K  + +++Q  T   + A  +   ++
Sbjct: 767  ERDKHLKEHQAHVENLEADIKRSEGELQQASA--KLDVFQSYQSATHEQTKAYEEQLAQL 824

Query: 575  VRESVEQQADSFKATRFNLETEWKN-------NYPRLRELDRNELFEKAKNEILDEVISL 627
             ++ ++ + +    T+   E E +        +  +++  D  +  EK  +E+  +V SL
Sbjct: 825  QQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL 884

Query: 628  SQVTPKHWEEILQQSLWERVSTHVI----ENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQ 683
            +QV    +E  L+    E+  T  I    EN+ L   +         T  +  K+     
Sbjct: 885  TQV----YESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKE-DSIH 939

Query: 684  LPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRV 743
            + N+  E  ++  +++  +   + K KE  +   K K   +E  +K+   N   E S + 
Sbjct: 940  ILNEEYETKFKNQEKKMEK--VKQKAKEMQETLKK-KLLDQEAKLKKELENTALELSQKE 996

Query: 744  IQHNA-------LEDRSISD---------KQQ------------------WDAAIYFMEE 769
             Q NA            ISD         K+Q                  W+  +    E
Sbjct: 997  KQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1056

Query: 770  ALQA----RLKDTENAIENM--------VGPDWKKRWLYWKNRTQEQCVHNETKNELEKM 817
             LQ     +L++ E  +  +           +   + + W    +E    + T NEL++ 
Sbjct: 1057 ELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLK--EEGVKQDTTLNELQEQ 1114

Query: 818  LKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQ 858
            LK    H   LA DE T ++ +LE   V+++ SL ++T+ Q
Sbjct: 1115 LKQKSAHVNSLAQDE-TKLKAHLEKLEVDLNKSLKENTFLQ 1154



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 41/223 (18%), Positives = 97/223 (43%), Gaps = 21/223 (9%)

Query: 182  SESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEEL 241
            +E+ +H  + ++G L   Q++++E  ++      Q+       K  +  K+ ++ + +++
Sbjct: 1783 AEAKQHEDQSMIGHL---QEELEEKNKKYSLIVAQHVEKEGG-KNNIQAKQNLENVFDDV 1838

Query: 242  LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDA-- 299
              T  + +   + LE++ KEL   ++++ +    HR   + L   Y E L  L   D   
Sbjct: 1839 QKTLQEKELTCQILEQKIKELDSCLVRQKEV---HRVEMEELTSKY-EKLQALQQMDGRN 1894

Query: 300  ------SYNTQD----HLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVT 349
                    NT++    HL +  ++ +  A    +   +A A    +  G+ + R    + 
Sbjct: 1895 KPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLR 1954

Query: 350  LSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKE 392
            +    H   L +   +E+D  +EE +   + ++EL+    +K+
Sbjct: 1955 MLRKEHQQEL-EILKKEYDQEREEKIKQEQEDLELKHNSTLKQ 1996


>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
            sapiens]
          Length = 1591

 Score = 38.9 bits (89), Expect = 0.024
 Identities = 46/243 (18%), Positives = 97/243 (39%), Gaps = 25/243 (10%)

Query: 531  IEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATR 590
            +  +     + F+  K LK  +++        LS        +   E + QQ + ++A  
Sbjct: 1155 LNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELS-----ALERQKDEKITQQEEKYEAII 1209

Query: 591  FNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH 650
             NLE + +      +E DR +L +K   E  DE I  +    K   E++++ L E+V   
Sbjct: 1210 QNLEKD-RQKLVSSQEQDREQLIQKLNCE-KDEAIQTALKEFKLEREVVEKELLEKVKHL 1267

Query: 651  VIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEE----------- 699
              +    PA  +    + +   +++ K   +K    + +E   +   EE           
Sbjct: 1268 ENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAE 1327

Query: 700  ----FSRFMTEPKGKEHD---DIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDR 752
                F+  +T  K ++ +   D+ DKLK  ++++   +      +ED  R+++     + 
Sbjct: 1328 QQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEE 1387

Query: 753  SIS 755
             +S
Sbjct: 1388 EVS 1390


>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
            sapiens]
          Length = 1594

 Score = 38.9 bits (89), Expect = 0.024
 Identities = 46/243 (18%), Positives = 97/243 (39%), Gaps = 25/243 (10%)

Query: 531  IEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATR 590
            +  +     + F+  K LK  +++        LS        +   E + QQ + ++A  
Sbjct: 1155 LNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELS-----ALERQKDEKITQQEEKYEAII 1209

Query: 591  FNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH 650
             NLE + +      +E DR +L +K   E  DE I  +    K   E++++ L E+V   
Sbjct: 1210 QNLEKD-RQKLVSSQEQDREQLIQKLNCE-KDEAIQTALKEFKLEREVVEKELLEKVKHL 1267

Query: 651  VIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEE----------- 699
              +    PA  +    + +   +++ K   +K    + +E   +   EE           
Sbjct: 1268 ENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAE 1327

Query: 700  ----FSRFMTEPKGKEHD---DIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDR 752
                F+  +T  K ++ +   D+ DKLK  ++++   +      +ED  R+++     + 
Sbjct: 1328 QQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEE 1387

Query: 753  SIS 755
             +S
Sbjct: 1388 EVS 1390


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score = 38.5 bits (88), Expect = 0.031
 Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 3/72 (4%)

Query: 895 DVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQL 954
           D V F   Q  +  T   L QQL   ++   + N++ +LE +  +  K+++ L+G RV+L
Sbjct: 148 DKVRFLEQQNQVLETKWELLQQL---DLNNCKNNLEPILEGYISNLRKQLETLSGDRVRL 204

Query: 955 AEDLKKVREIQE 966
             +L+ VRE+ E
Sbjct: 205 DSELRSVREVVE 216


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,998,006
Number of Sequences: 37866
Number of extensions: 1553208
Number of successful extensions: 8457
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 247
Number of HSP's that attempted gapping in prelim test: 7549
Number of HSP's gapped (non-prelim): 1207
length of query: 979
length of database: 18,247,518
effective HSP length: 112
effective length of query: 867
effective length of database: 14,006,526
effective search space: 12143658042
effective search space used: 12143658042
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.