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Search of human proteins with 18860835
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
(961 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 1921 0.0
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 1910 0.0
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 1903 0.0
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 1892 0.0
gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] 1832 0.0
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 1821 0.0
gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens] 1814 0.0
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 1803 0.0
gi|56549125 dynamin 2 isoform 4 [Homo sapiens] 114 4e-25
gi|56549123 dynamin 2 isoform 2 [Homo sapiens] 114 4e-25
gi|56549121 dynamin 2 isoform 1 [Homo sapiens] 114 4e-25
gi|56549119 dynamin 2 isoform 3 [Homo sapiens] 114 4e-25
gi|56549117 dynamin 1 isoform 2 [Homo sapiens] 107 5e-23
gi|59853099 dynamin 1 isoform 1 [Homo sapiens] 107 5e-23
gi|171460914 dynamin 1-like isoform 1 [Homo sapiens] 104 3e-22
gi|171460918 dynamin 1-like isoform 3 [Homo sapiens] 104 3e-22
gi|171460916 dynamin 1-like isoform 2 [Homo sapiens] 104 3e-22
gi|42544243 dynamin 3 isoform a [Homo sapiens] 103 8e-22
gi|209915561 dynamin 3 isoform b [Homo sapiens] 103 8e-22
gi|222136619 myxovirus resistance protein 1 [Homo sapiens] 102 2e-21
gi|222136617 myxovirus resistance protein 1 [Homo sapiens] 102 2e-21
gi|11342664 myxovirus resistance protein 2 [Homo sapiens] 99 2e-20
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 41 0.006
gi|116235456 ring finger protein 214 [Homo sapiens] 41 0.006
gi|116235451 ring finger protein 214 [Homo sapiens] 41 0.006
gi|224593756 hypothetical protein LOC164127 [Homo sapiens] 40 0.010
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 39 0.018
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 39 0.023
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 39 0.023
gi|28173564 keratin 73 [Homo sapiens] 39 0.030
>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
Length = 961
Score = 1921 bits (4976), Expect = 0.0
Identities = 961/961 (100%), Positives = 961/961 (100%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHFRKGLLGELIL 180
QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHFRKGLLGELIL
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHFRKGLLGELIL 180
Query: 181 LQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKE 240
LQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKE
Sbjct: 181 LQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKE 240
Query: 241 NKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSA 300
NKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSA
Sbjct: 241 NKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSA 300
Query: 301 GKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAAL 360
GKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAAL
Sbjct: 301 GKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAAL 360
Query: 361 RHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIF 420
RHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIF
Sbjct: 361 RHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIF 420
Query: 421 SISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASP 480
SISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASP
Sbjct: 421 SISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASP 480
Query: 481 SRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQV 540
SRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQV
Sbjct: 481 SRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQV 540
Query: 541 TTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKN 600
TTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKN
Sbjct: 541 TTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKN 600
Query: 601 EILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQ 660
EILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQ
Sbjct: 601 EILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQ 660
Query: 661 WTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAE 720
WTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAE
Sbjct: 661 WTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAE 720
Query: 721 DSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWK 780
DSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWK
Sbjct: 721 DSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWK 780
Query: 781 NRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQ 840
NRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQ
Sbjct: 781 NRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQ 840
Query: 841 VYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLT 900
VYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLT
Sbjct: 841 VYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLT 900
Query: 901 NTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQE 960
NTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQE
Sbjct: 901 NTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQE 960
Query: 961 K 961
K
Sbjct: 961 K 961
>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
Length = 979
Score = 1910 bits (4947), Expect = 0.0
Identities = 961/979 (98%), Positives = 961/979 (98%), Gaps = 18/979 (1%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFG------------------SPEETAFRATDR 162
QWKDMIPDLSEYKWIVPDIVWEIDEYIDFG SPEETAFRATDR
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR 180
Query: 163 GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE 222
GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE
Sbjct: 181 GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE 240
Query: 223 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 282
LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS
Sbjct: 241 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 300
Query: 283 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 342
YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF
Sbjct: 301 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 360
Query: 343 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 402
KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG
Sbjct: 361 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 420
Query: 403 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 462
VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR
Sbjct: 421 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 480
Query: 463 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 522
TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE
Sbjct: 481 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 540
Query: 523 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 582
FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN
Sbjct: 541 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 600
Query: 583 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 642
YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA
Sbjct: 601 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 660
Query: 643 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 702
QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK
Sbjct: 661 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 720
Query: 703 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 762
EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN
Sbjct: 721 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 780
Query: 763 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 822
AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL
Sbjct: 781 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 840
Query: 823 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 882
ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW
Sbjct: 841 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 900
Query: 883 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 942
RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK
Sbjct: 901 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 960
Query: 943 VREIQEKLDAFIEALHQEK 961
VREIQEKLDAFIEALHQEK
Sbjct: 961 VREIQEKLDAFIEALHQEK 979
>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
Length = 997
Score = 1903 bits (4929), Expect = 0.0
Identities = 961/997 (96%), Positives = 961/997 (96%), Gaps = 36/997 (3%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF------------------------------- 149
QWKDMIPDLSEYKWIVPDIVWEIDEYIDF
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
Query: 150 -----GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA 204
GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA
Sbjct: 181 DFFTSGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA 240
Query: 205 QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 264
QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS
Sbjct: 241 QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 300
Query: 265 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 324
LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT
Sbjct: 301 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 360
Query: 325 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 384
RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS
Sbjct: 361 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 420
Query: 385 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 444
LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA
Sbjct: 421 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 480
Query: 445 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 504
ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT
Sbjct: 481 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 540
Query: 505 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 564
GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ
Sbjct: 541 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 600
Query: 565 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 624
ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS
Sbjct: 601 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 660
Query: 625 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 684
LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR
Sbjct: 661 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 720
Query: 685 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 744
FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA
Sbjct: 721 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 780
Query: 745 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 804
AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE
Sbjct: 781 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 840
Query: 805 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 864
EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY
Sbjct: 841 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 900
Query: 865 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 924
QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK
Sbjct: 901 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 960
Query: 925 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 961
KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 961 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997
>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
Length = 1015
Score = 1892 bits (4900), Expect = 0.0
Identities = 961/1015 (94%), Positives = 961/1015 (94%), Gaps = 54/1015 (5%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYI--------------------------------- 147
QWKDMIPDLSEYKWIVPDIVWEIDEYI
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
Query: 148 DF---------------------GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 186
DF GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ
Sbjct: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 240
Query: 187 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 246
EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK
Sbjct: 241 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 300
Query: 247 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 306
LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL
Sbjct: 301 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 360
Query: 307 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 366
EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL
Sbjct: 361 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 420
Query: 367 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 426
RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY
Sbjct: 421 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 480
Query: 427 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 486
MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI
Sbjct: 481 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 540
Query: 487 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 546
IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS
Sbjct: 541 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 600
Query: 547 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 606
LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV
Sbjct: 601 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 660
Query: 607 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 666
ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL
Sbjct: 661 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 720
Query: 667 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 726
PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI
Sbjct: 721 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 780
Query: 727 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 786
QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ
Sbjct: 781 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 840
Query: 787 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 846
CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF
Sbjct: 841 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 900
Query: 847 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 906
LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR
Sbjct: 901 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 960
Query: 907 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 961
LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 961 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 1015
>gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens]
Length = 924
Score = 1832 bits (4746), Expect = 0.0
Identities = 924/961 (96%), Positives = 924/961 (96%), Gaps = 37/961 (3%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHFRKGLLGELIL 180
QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHF
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHF---------- 170
Query: 181 LQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKE 240
RKVSDKEKIDQLQEELLHTQLKYQRILERLEKE
Sbjct: 171 ---------------------------RKVSDKEKIDQLQEELLHTQLKYQRILERLEKE 203
Query: 241 NKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSA 300
NKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSA
Sbjct: 204 NKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSA 263
Query: 301 GKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAAL 360
GKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAAL
Sbjct: 264 GKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAAL 323
Query: 361 RHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIF 420
RHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIF
Sbjct: 324 RHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIF 383
Query: 421 SISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASP 480
SISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASP
Sbjct: 384 SISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASP 443
Query: 481 SRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQV 540
SRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQV
Sbjct: 444 SRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQV 503
Query: 541 TTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKN 600
TTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKN
Sbjct: 504 TTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKN 563
Query: 601 EILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQ 660
EILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQ
Sbjct: 564 EILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQ 623
Query: 661 WTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAE 720
WTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAE
Sbjct: 624 WTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAE 683
Query: 721 DSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWK 780
DSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWK
Sbjct: 684 DSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWK 743
Query: 781 NRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQ 840
NRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQ
Sbjct: 744 NRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQ 803
Query: 841 VYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLT 900
VYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLT
Sbjct: 804 VYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLT 863
Query: 901 NTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQE 960
NTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQE
Sbjct: 864 NTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQE 923
Query: 961 K 961
K
Sbjct: 924 K 924
>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
Length = 942
Score = 1821 bits (4717), Expect = 0.0
Identities = 924/979 (94%), Positives = 924/979 (94%), Gaps = 55/979 (5%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFG------------------SPEETAFRATDR 162
QWKDMIPDLSEYKWIVPDIVWEIDEYIDFG SPEETAFRATDR
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFGHKLVSEVIGASDLLLLLGSPEETAFRATDR 180
Query: 163 GSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEE 222
GSESDKHFR KVSDKEKIDQLQEE
Sbjct: 181 GSESDKHFR-------------------------------------KVSDKEKIDQLQEE 203
Query: 223 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 282
LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS
Sbjct: 204 LLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDAS 263
Query: 283 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 342
YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF
Sbjct: 264 YNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF 323
Query: 343 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 402
KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG
Sbjct: 324 KDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPG 383
Query: 403 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 462
VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR
Sbjct: 384 VINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRR 443
Query: 463 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 522
TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE
Sbjct: 444 TIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEE 503
Query: 523 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 582
FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN
Sbjct: 504 FFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNN 563
Query: 583 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 642
YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA
Sbjct: 564 YPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAA 623
Query: 643 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 702
QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK
Sbjct: 624 QTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLK 683
Query: 703 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 762
EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN
Sbjct: 684 EAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTEN 743
Query: 763 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 822
AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL
Sbjct: 744 AIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNL 803
Query: 823 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 882
ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW
Sbjct: 804 ESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFW 863
Query: 883 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 942
RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK
Sbjct: 864 RIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKK 923
Query: 943 VREIQEKLDAFIEALHQEK 961
VREIQEKLDAFIEALHQEK
Sbjct: 924 VREIQEKLDAFIEALHQEK 942
>gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens]
Length = 960
Score = 1814 bits (4699), Expect = 0.0
Identities = 924/997 (92%), Positives = 924/997 (92%), Gaps = 73/997 (7%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF------------------------------- 149
QWKDMIPDLSEYKWIVPDIVWEIDEYIDF
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
Query: 150 -----GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYA 204
GSPEETAFRATDRGSESDKHFR
Sbjct: 181 DFFTSGSPEETAFRATDRGSESDKHFR--------------------------------- 207
Query: 205 QQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 264
KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS
Sbjct: 208 ----KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKS 263
Query: 265 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 324
LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT
Sbjct: 264 LIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMT 323
Query: 325 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 384
RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS
Sbjct: 324 RSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETIS 383
Query: 385 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 444
LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA
Sbjct: 384 LNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDA 443
Query: 445 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 504
ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT
Sbjct: 444 ERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVT 503
Query: 505 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 564
GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ
Sbjct: 504 GKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQ 563
Query: 565 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 624
ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS
Sbjct: 564 ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQS 623
Query: 625 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 684
LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR
Sbjct: 624 LWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSR 683
Query: 685 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 744
FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA
Sbjct: 684 FMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDA 743
Query: 745 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 804
AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE
Sbjct: 744 AIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNE 803
Query: 805 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 864
EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY
Sbjct: 804 EHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYY 863
Query: 865 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 924
QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK
Sbjct: 864 QRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEK 923
Query: 925 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 961
KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 924 KIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 960
>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
Length = 978
Score = 1803 bits (4670), Expect = 0.0
Identities = 924/1015 (91%), Positives = 924/1015 (91%), Gaps = 91/1015 (8%)
Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ
Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60
Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD
Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120
Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYI--------------------------------- 147
QWKDMIPDLSEYKWIVPDIVWEIDEYI
Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180
Query: 148 DF---------------------GSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 186
DF GSPEETAFRATDRGSESDKHFR
Sbjct: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFR--------------- 225
Query: 187 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 246
KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK
Sbjct: 226 ----------------------KVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 263
Query: 247 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 306
LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL
Sbjct: 264 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 323
Query: 307 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 366
EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL
Sbjct: 324 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 383
Query: 367 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 426
RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY
Sbjct: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443
Query: 427 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 486
MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI
Sbjct: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503
Query: 487 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 546
IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS
Sbjct: 504 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 563
Query: 547 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 606
LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV
Sbjct: 564 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 623
Query: 607 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 666
ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL
Sbjct: 624 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 683
Query: 667 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 726
PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI
Sbjct: 684 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 743
Query: 727 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 786
QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ
Sbjct: 744 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 803
Query: 787 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 846
CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF
Sbjct: 804 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 863
Query: 847 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 906
LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR
Sbjct: 864 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 923
Query: 907 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 961
LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK
Sbjct: 924 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 978
>gi|56549125 dynamin 2 isoform 4 [Homo sapiens]
Length = 866
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
Query: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
R + + H S++F D +R EIE + +SP
Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
Query: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
Query: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 503 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
Query: 560 SVEQQADSFKATRFNLE---TEWKNNYP 584
S+ ++ +LE E+KN P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
>gi|56549123 dynamin 2 isoform 2 [Homo sapiens]
Length = 870
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
Query: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
R + + H S++F D +R EIE + +SP
Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
Query: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
Query: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 503 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
Query: 560 SVEQQADSFKATRFNLE---TEWKNNYP 584
S+ ++ +LE E+KN P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
>gi|56549121 dynamin 2 isoform 1 [Homo sapiens]
Length = 870
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
Query: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
R + + H S++F D +R EIE + +SP
Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
Query: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
Query: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 503 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
Query: 560 SVEQQADSFKATRFNLE---TEWKNNYP 584
S+ ++ +LE E+KN P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
>gi|56549119 dynamin 2 isoform 3 [Homo sapiens]
Length = 866
Score = 114 bits (285), Expect = 4e-25
Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
+ LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64
Query: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
R + + H S++F D +R EIE + +SP
Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119
Query: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179
Query: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 503 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559
V E I A E +FF + + A ++ T +L ++ +RE
Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291
Query: 560 SVEQQADSFKATRFNLE---TEWKNNYP 584
S+ ++ +LE E+KN P
Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319
>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
Length = 851
Score = 107 bits (267), Expect = 5e-23
Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
+ LI + + + D S N LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
Query: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
+TR P+ + L A F + K D +R EIE + +SP
Sbjct: 64 VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
Query: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
I+L V P + + LVDLPG+ PD + I + ++ N +IL + +
Sbjct: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
Query: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
D S + ++DP G+RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 503 VTGKG---NSSESIEAIREYEEEFF 524
V + + I A E +FF
Sbjct: 235 VNRSQKDIDGKKDITAALAAERKFF 259
>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
Length = 864
Score = 107 bits (267), Expect = 5e-23
Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
+ LI + + + D S N LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
Query: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
+TR P+ + L A F + K D +R EIE + +SP
Sbjct: 64 VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119
Query: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
I+L V P + + LVDLPG+ PD + I + ++ N +IL + +
Sbjct: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179
Query: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
D S + ++DP G+RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234
Query: 503 VTGKG---NSSESIEAIREYEEEFF 524
V + + I A E +FF
Sbjct: 235 VNRSQKDIDGKKDITAALAAERKFF 259
>gi|171460914 dynamin 1-like isoform 1 [Homo sapiens]
Length = 736
Score = 104 bits (260), Expect = 3e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
Query: 323 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 366
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
Query: 367 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 426
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
Query: 427 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 486
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
Query: 487 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 525
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
>gi|171460918 dynamin 1-like isoform 3 [Homo sapiens]
Length = 699
Score = 104 bits (260), Expect = 3e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
Query: 323 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 366
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
Query: 367 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 426
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
Query: 427 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 486
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
Query: 487 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 525
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
>gi|171460916 dynamin 1-like isoform 2 [Homo sapiens]
Length = 710
Score = 104 bits (260), Expect = 3e-22
Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G +
Sbjct: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57
Query: 323 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 366
+TR P+ + L HV+ K + E + EE D +R EIE
Sbjct: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113
Query: 367 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 426
+ VSPE I L + P + + LVDLPG+ D + I + +
Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173
Query: 427 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 486
+ NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + +
Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229
Query: 487 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 525
+ G++ P+K LG VV N ++IR+ E F Q
Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270
>gi|42544243 dynamin 3 isoform a [Homo sapiens]
Length = 863
Score = 103 bits (257), Expect = 8e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
Query: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
Query: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
Query: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
Query: 503 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
Query: 560 SVEQQADSFKATRFNLETE---WKNNYP 584
++ + + ++E E +KN P
Sbjct: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
>gi|209915561 dynamin 3 isoform b [Homo sapiens]
Length = 859
Score = 103 bits (257), Expect = 8e-22
Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%)
Query: 263 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 322
+ LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG +
Sbjct: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63
Query: 323 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 382
+TR P+ + L A F + K D +R EIE + +S
Sbjct: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119
Query: 383 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 442
I+L V P + + L+DLPG+ PD + I + ++ N +IL + +
Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179
Query: 443 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V
Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234
Query: 503 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 559
V + + I+A E +FF + + A ++ T +L ++ +R+
Sbjct: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291
Query: 560 SVEQQADSFKATRFNLETE---WKNNYP 584
++ + + ++E E +KN P
Sbjct: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319
>gi|222136619 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 102 bits (253), Expect = 2e-21
Identities = 113/478 (23%), Positives = 210/478 (43%), Gaps = 29/478 (6%)
Query: 248 VLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQD-HLPRVVVVGDQSAGKTSVL 306
V QK+ + L + +D++ A QD LP + V+GDQS+GK+SVL
Sbjct: 28 VAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVL 87
Query: 307 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF-KDSSREFDLTKEEDLAALRHEIE 365
E ++ + PRGSG ++TR P+ + L + + K S +++++ + D + + EI
Sbjct: 88 EALSGVAL-PRGSG-IVTRCPLVLKLKKLVNEDKWRGKVSYQDYEI-EISDASEVEKEIN 144
Query: 366 LRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKA 425
EG +S E I+L + + + L+DLPG+ D I ++ K
Sbjct: 145 KAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKK 204
Query: 426 YMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQ 485
Y+Q I L + +VD + + ++DP G RTI +LTK DL +K + ++
Sbjct: 205 YIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDK--GTEDKVVD 262
Query: 486 IIEGKLFPMKALGYFAVVTGKG----NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVT 541
++ +F +K GY +V +G S+ + E+ FF+N + +L+ + T
Sbjct: 263 VVRNLVFHLKK-GYM-IVKCRGQQEIQDQLSLSEALQREKIFFENHPYFR-DLLEEGKAT 319
Query: 542 TRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNE----LFEK 597
L+ ++ + +S+ + K T + E + + E D NE L +K
Sbjct: 320 VPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPE-DENEKMFFLIDK 378
Query: 598 AKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH----VIENIYLPAAQTMNSGTFNTT 653
N ++ +L Q EE ++ R H +IEN + + + +
Sbjct: 379 V-NAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKIL-----SRK 432
Query: 654 VDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIK 711
+ Q+ ++LP +ET+ ++ + + EP + D ++ A + SIK
Sbjct: 433 IQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIK 490
>gi|222136617 myxovirus resistance protein 1 [Homo sapiens]
Length = 662
Score = 102 bits (253), Expect = 2e-21
Identities = 113/478 (23%), Positives = 210/478 (43%), Gaps = 29/478 (6%)
Query: 248 VLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQD-HLPRVVVVGDQSAGKTSVL 306
V QK+ + L + +D++ A QD LP + V+GDQS+GK+SVL
Sbjct: 28 VAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVL 87
Query: 307 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF-KDSSREFDLTKEEDLAALRHEIE 365
E ++ + PRGSG ++TR P+ + L + + K S +++++ + D + + EI
Sbjct: 88 EALSGVAL-PRGSG-IVTRCPLVLKLKKLVNEDKWRGKVSYQDYEI-EISDASEVEKEIN 144
Query: 366 LRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKA 425
EG +S E I+L + + + L+DLPG+ D I ++ K
Sbjct: 145 KAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKK 204
Query: 426 YMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQ 485
Y+Q I L + +VD + + ++DP G RTI +LTK DL +K + ++
Sbjct: 205 YIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDK--GTEDKVVD 262
Query: 486 IIEGKLFPMKALGYFAVVTGKG----NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVT 541
++ +F +K GY +V +G S+ + E+ FF+N + +L+ + T
Sbjct: 263 VVRNLVFHLKK-GYM-IVKCRGQQEIQDQLSLSEALQREKIFFENHPYFR-DLLEEGKAT 319
Query: 542 TRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNE----LFEK 597
L+ ++ + +S+ + K T + E + + E D NE L +K
Sbjct: 320 VPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPE-DENEKMFFLIDK 378
Query: 598 AKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH----VIENIYLPAAQTMNSGTFNTT 653
N ++ +L Q EE ++ R H +IEN + + + +
Sbjct: 379 V-NAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKIL-----SRK 432
Query: 654 VDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIK 711
+ Q+ ++LP +ET+ ++ + + EP + D ++ A + SIK
Sbjct: 433 IQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIK 490
>gi|11342664 myxovirus resistance protein 2 [Homo sapiens]
Length = 715
Score = 98.6 bits (244), Expect = 2e-20
Identities = 65/214 (30%), Positives = 107/214 (50%), Gaps = 6/214 (2%)
Query: 289 LPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSRE 348
LP + V+GDQS+GK+SVLE ++ + PRGSG ++TR P+ + L + P + S R
Sbjct: 118 LPAIAVIGDQSSGKSSVLEALSGVAL-PRGSG-IVTRCPLVLKLKKQPCEAWAGRISYRN 175
Query: 349 FDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVT 408
+L + +D + EI G +S E ISL + P + + ++DLPG+
Sbjct: 176 TEL-ELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDLTIIDLPGITRVAV 234
Query: 409 SGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLT 468
D I ++ K Y+Q I L + +VD + + ++DP G RTI +LT
Sbjct: 235 DNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHEVDPEGDRTIGILT 294
Query: 469 KVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 502
K DL ++ + + ++ +P+K GY V
Sbjct: 295 KPDLMDR--GTEKSVMNVVRNLTYPLKK-GYMIV 325
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 40.8 bits (94), Expect = 0.006
Identities = 25/92 (27%), Positives = 50/92 (54%), Gaps = 7/92 (7%)
Query: 179 ILLQQQIQEHEEEARRAAGQYSTSYAQQKRK-------VSDKEKIDQLQEELLHTQLKYQ 231
+L + Q QE A+ A Q + A++KRK + +EKI ++Q+ + +L+ Q
Sbjct: 903 LLRKLQKQEQARVAKEAKKQQAIMAAEEKRKQKEQIKIMKQQEKIKRIQQIRMEKELRAQ 962
Query: 232 RILERLEKENKELRKLVLQKDDKGIHHRKLKK 263
+ILE +K+ +E L + +K I +++++
Sbjct: 963 QILEAKKKKKEEAANAKLLEAEKRIKEKEMRR 994
>gi|116235456 ring finger protein 214 [Homo sapiens]
Length = 703
Score = 40.8 bits (94), Expect = 0.006
Identities = 35/159 (22%), Positives = 72/159 (45%), Gaps = 12/159 (7%)
Query: 154 ETAFRATDRGSESDKHFRKGL---LGELILLQQQIQEHEEEARRAAGQYSTSYAQ-QKRK 209
+T F+ D +D+ K L + E LL+++ QE ++ R+ Q Q Q+R+
Sbjct: 206 QTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRR 265
Query: 210 VSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMY 269
+ + ++ + + +K + +++EKE KE L ++D K + +K +++
Sbjct: 266 EEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF--LQKEQDLKAEIEKLCEKGRREVW 323
Query: 270 SEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEM 308
LD L + D N R ++ + A K +L +
Sbjct: 324 EMELDRLKNQDGEIN------RNIMEETERAWKAEILSL 356
>gi|116235451 ring finger protein 214 [Homo sapiens]
Length = 703
Score = 40.8 bits (94), Expect = 0.006
Identities = 35/159 (22%), Positives = 72/159 (45%), Gaps = 12/159 (7%)
Query: 154 ETAFRATDRGSESDKHFRKGL---LGELILLQQQIQEHEEEARRAAGQYSTSYAQ-QKRK 209
+T F+ D +D+ K L + E LL+++ QE ++ R+ Q Q Q+R+
Sbjct: 206 QTDFKTADSEVNTDQDIEKNLDKMMTERTLLKERYQEVLDKQRQVENQLQVQLKQLQQRR 265
Query: 210 VSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMY 269
+ + ++ + + +K + +++EKE KE L ++D K + +K +++
Sbjct: 266 EEEMKNHQEILKAIQDVTIKREETKKKIEKEKKEF--LQKEQDLKAEIEKLCEKGRREVW 323
Query: 270 SEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEM 308
LD L + D N R ++ + A K +L +
Sbjct: 324 EMELDRLKNQDGEIN------RNIMEETERAWKAEILSL 356
>gi|224593756 hypothetical protein LOC164127 [Homo sapiens]
Length = 623
Score = 40.0 bits (92), Expect = 0.010
Identities = 36/158 (22%), Positives = 75/158 (47%), Gaps = 6/158 (3%)
Query: 162 RGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSD--KEKIDQL 219
R E + RK EL Q+ +E ++AR AG+ +KR + + EKI Q
Sbjct: 458 RSQEIHQGLRKERQRELREKAQKEEEQLQQARWRAGESEEQRKMRKRILVELADEKIRQA 517
Query: 220 QEELLHT---QLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVL 276
+ + T ++++ R L L ++N + KL +K++K H +K+++ V +
Sbjct: 518 RSHVHKTTRDKVQHLRELNHLREKNHHILKLKAEKEEK-CHIEGIKEAIKKKEQRVQHIS 576
Query: 277 SDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARI 314
D ++ LP+ +++ +S+ +M+ +A++
Sbjct: 577 QGKDPNFQEFQKLPQASRREERAPPNSSLDQMVLEAQL 614
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 39.3 bits (90), Expect = 0.018
Identities = 145/792 (18%), Positives = 311/792 (39%), Gaps = 129/792 (16%)
Query: 212 DKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSL---IDM 268
DK K+ +L +L T ++Q + EK NK L +DK + +KL + L +D+
Sbjct: 1167 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSL-------EDKSLEFKKLSEELAIQLDI 1219
Query: 269 YSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPV 328
+ + L + + + + + + + +A + + +
Sbjct: 1220 CCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLR 1279
Query: 329 KVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVK 388
++T + +++ F+ ++ + + KE + +++ +IE ++ E +L +
Sbjct: 1280 QLTEEQNTLNIS-FQQATHQLE-EKENQIKSMKADIE-----------SLVTEKEALQKE 1326
Query: 389 GPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSI 448
G Q+ A + + I + K +N NA+ L ++ + ++
Sbjct: 1327 GGNQQQA----------------ASEKESCITQLKKELSENINAVTLMKEE--LKEKKVE 1368
Query: 449 VTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGK---LFPMKALGYFAVVTG 505
++ L Q+ + + + L+EK A S +Q E K L ++ L F V T
Sbjct: 1369 ISSLSKQLTD---LNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLS-FKVDTL 1424
Query: 506 KGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVS---------DCFWKM 556
++E + ++ +F + K + S HQ T + L + + D +
Sbjct: 1425 SKEKISALEQVDDWSNKFSEWKKKAQ-SRFTQHQNTVKELQIQLELKSKEAYEKDEQINL 1483
Query: 557 VRESVEQQADSFKATR--------------FNLETEWKNNYPRLRELDRNELFEKAKNEI 602
++E ++QQ F + NLETE K+ R+ EL+ + + + E
Sbjct: 1484 LKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIES 1543
Query: 603 LDEVI-SLSQVTPKHWEEILQ-----QSLWERVSTHVIE----------NIYLPAAQTMN 646
L+EV+ + +Q +E++Q Q L E V E +Y A+
Sbjct: 1544 LNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1603
Query: 647 SGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVK 706
V++ +K K+ KA+E + L+ E + + E K K I K+ +
Sbjct: 1604 KKKELEHVNLSVK---SKEEELKALE---DRLESESAAKLAELKRKAEQKIAAIKKQLLS 1657
Query: 707 EESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA-IE 765
+ K ++ E L + + Q+ + ++ +EE +LK E++ E
Sbjct: 1658 QMEEKEEQYKKGTESHLSELN---------TKLQEREREVHILEE----KLKSVESSQSE 1704
Query: 766 NMVGPDWKKRWLYWKNRTQ---EQCV---HNETKNELEKMLKCNEEHPAYLASDEITTVR 819
++ P K + + + + CV + E + L++ L E+ + ++ TV
Sbjct: 1705 TLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVS 1764
Query: 820 KNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNH----CNLCRRGFYYYQRHFVDSELEC 875
+ E R + LIK H ++H ++ + H + + V+ E
Sbjct: 1765 SHFEMR-CQYQERLIK-LEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGK 1822
Query: 876 NDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQ 935
N++ ++ + TL+++ ++ LE+ +KE+ D +K++ RV+
Sbjct: 1823 NNIQAKQNLENVFDDVQKTLQEKELTCQI--LEQKIKEL--DSCLVRQKEV-----HRVE 1873
Query: 936 LAEDLKKVREIQ 947
+ E K ++Q
Sbjct: 1874 MEELTSKYEKLQ 1885
Score = 36.6 bits (83), Expect = 0.12
Identities = 146/761 (19%), Positives = 300/761 (39%), Gaps = 106/761 (13%)
Query: 153 EETAFRATDRGSESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSD 212
EE + E K K E I LQQ++ ++E + S + +K+ +
Sbjct: 427 EEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHE 486
Query: 213 KE---KIDQLQEELLHTQLKYQRILE-RLEKENKELRKLVLQKDDK---GIHHRKLKKSL 265
KE K +L ++L + ++Q ++ LEK E K+ +K+ + + +L+K
Sbjct: 487 KELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKA 546
Query: 266 IDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTR 325
I SE + L D T R ++ +S+ + S+ E Q++ +
Sbjct: 547 ILTESE--NKLRDLQQEAETY----RTRILELESSLEKSLQENKNQSKDLAVHLEAEKNK 600
Query: 326 SPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISL 385
++T+ H L + + D E L L+ + + M K ++E C ET+ L
Sbjct: 601 HNKEITVMVEKHKTEL-ESLKHQQDALWTEKLQVLKQQYQTEMEK-LREKCEQEKETL-L 657
Query: 386 NVKGPGLQRMV------LVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQD 439
K Q + ++ V T ++ + E + + K + + ++D
Sbjct: 658 KDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEE-----LSVLKD 712
Query: 440 GSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGY 499
+ ++ + + Q + H ++ ++ +++ S R ++ ++ ++ ++ L
Sbjct: 713 QTDKMKQELEAKMDEQKNHHQQQVDSII------KEHEVSIQRTEKALKDQINQLELLLK 766
Query: 500 FAVVTGKGNSS--ESIEA-IREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKM 556
K + + E++EA I+ E E Q S K + +++Q T + A + ++
Sbjct: 767 ERDKHLKEHQAHVENLEADIKRSEGELQQASA--KLDVFQSYQSATHEQTKAYEEQLAQL 824
Query: 557 VRESVEQQADSFKATRFNLETEWKN-------NYPRLRELDRNELFEKAKNEILDEVISL 609
++ ++ + + T+ E E + + +++ D + EK +E+ +V SL
Sbjct: 825 QQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL 884
Query: 610 SQVTPKHWEEILQQSLWERVSTHVI----ENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQ 665
+QV +E L+ E+ T I EN+ L + T + K+
Sbjct: 885 TQV----YESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKE-DSIH 939
Query: 666 LPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRV 725
+ N+ E ++ +++ + + K KE + K K +E +K+ N E S +
Sbjct: 940 ILNEEYETKFKNQEKKMEK--VKQKAKEMQETLKK-KLLDQEAKLKKELENTALELSQKE 996
Query: 726 IQHNA-------LEDRSISD---------KQQ------------------WDAAIYFMEE 751
Q NA ISD K+Q W+ + E
Sbjct: 997 KQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1056
Query: 752 ALQA----RLKDTENAIENM--------VGPDWKKRWLYWKNRTQEQCVHNETKNELEKM 799
LQ +L++ E + + + + + W +E + T NEL++
Sbjct: 1057 ELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLK--EEGVKQDTTLNELQEQ 1114
Query: 800 LKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQ 840
LK H LA DE T ++ +LE V+++ SL ++T+ Q
Sbjct: 1115 LKQKSAHVNSLAQDE-TKLKAHLEKLEVDLNKSLKENTFLQ 1154
Score = 33.5 bits (75), Expect = 0.98
Identities = 41/223 (18%), Positives = 97/223 (43%), Gaps = 21/223 (9%)
Query: 164 SESDKHFRKGLLGELILLQQQIQEHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEEL 223
+E+ +H + ++G L Q++++E ++ Q+ K + K+ ++ + +++
Sbjct: 1783 AEAKQHEDQSMIGHL---QEELEEKNKKYSLIVAQHVEKEGG-KNNIQAKQNLENVFDDV 1838
Query: 224 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDA-- 281
T + + + LE++ KEL ++++ + HR + L Y E L L D
Sbjct: 1839 QKTLQEKELTCQILEQKIKELDSCLVRQKEV---HRVEMEELTSKY-EKLQALQQMDGRN 1894
Query: 282 ------SYNTQD----HLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVT 331
NT++ HL + ++ + A + +A A + G+ + R +
Sbjct: 1895 KPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLR 1954
Query: 332 LSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKE 374
+ H L + +E+D +EE + + ++EL+ +K+
Sbjct: 1955 MLRKEHQQEL-EILKKEYDQEREEKIKQEQEDLELKHNSTLKQ 1996
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 38.9 bits (89), Expect = 0.023
Identities = 46/243 (18%), Positives = 97/243 (39%), Gaps = 25/243 (10%)
Query: 513 IEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATR 572
+ + + F+ K LK +++ LS + E + QQ + ++A
Sbjct: 1155 LNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELS-----ALERQKDEKITQQEEKYEAII 1209
Query: 573 FNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH 632
NLE + + +E DR +L +K E DE I + K E++++ L E+V
Sbjct: 1210 QNLEKD-RQKLVSSQEQDREQLIQKLNCE-KDEAIQTALKEFKLEREVVEKELLEKVKHL 1267
Query: 633 VIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEE----------- 681
+ PA + + + +++ K +K + +E + EE
Sbjct: 1268 ENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAE 1327
Query: 682 ----FSRFMTEPKGKEHD---DIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDR 734
F+ +T K ++ + D+ DKLK ++++ + +ED R+++ +
Sbjct: 1328 QQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEE 1387
Query: 735 SIS 737
+S
Sbjct: 1388 EVS 1390
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 38.9 bits (89), Expect = 0.023
Identities = 46/243 (18%), Positives = 97/243 (39%), Gaps = 25/243 (10%)
Query: 513 IEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATR 572
+ + + F+ K LK +++ LS + E + QQ + ++A
Sbjct: 1155 LNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELS-----ALERQKDEKITQQEEKYEAII 1209
Query: 573 FNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH 632
NLE + + +E DR +L +K E DE I + K E++++ L E+V
Sbjct: 1210 QNLEKD-RQKLVSSQEQDREQLIQKLNCE-KDEAIQTALKEFKLEREVVEKELLEKVKHL 1267
Query: 633 VIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEE----------- 681
+ PA + + + +++ K +K + +E + EE
Sbjct: 1268 ENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAE 1327
Query: 682 ----FSRFMTEPKGKEHD---DIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDR 734
F+ +T K ++ + D+ DKLK ++++ + +ED R+++ +
Sbjct: 1328 QQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEE 1387
Query: 735 SIS 737
+S
Sbjct: 1388 EVS 1390
>gi|28173564 keratin 73 [Homo sapiens]
Length = 540
Score = 38.5 bits (88), Expect = 0.030
Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 3/72 (4%)
Query: 877 DVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQL 936
D V F Q + T L QQL ++ + N++ +LE + + K+++ L+G RV+L
Sbjct: 148 DKVRFLEQQNQVLETKWELLQQL---DLNNCKNNLEPILEGYISNLRKQLETLSGDRVRL 204
Query: 937 AEDLKKVREIQE 948
+L+ VRE+ E
Sbjct: 205 DSELRSVREVVE 216
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,453,217
Number of Sequences: 37866
Number of extensions: 1532376
Number of successful extensions: 8431
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 78
Number of HSP's successfully gapped in prelim test: 240
Number of HSP's that attempted gapping in prelim test: 7550
Number of HSP's gapped (non-prelim): 1195
length of query: 961
length of database: 18,247,518
effective HSP length: 112
effective length of query: 849
effective length of database: 14,006,526
effective search space: 11891540574
effective search space used: 11891540574
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.