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Search of human proteins with 188497667
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188497667 trafficking protein, kinesin binding 2 [Homo
sapiens]
(914 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188497667 trafficking protein, kinesin binding 2 [Homo sapiens] 1795 0.0
gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 ... 730 0.0
gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 K... 516 e-146
gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo sap... 127 5e-29
gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo sap... 115 2e-25
gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo sap... 115 2e-25
gi|119120918 coiled-coil domain containing 64 [Homo sapiens] 71 4e-12
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 70 1e-11
gi|55770834 centromere protein F [Homo sapiens] 66 1e-10
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 63 1e-09
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 60 7e-09
gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo ... 60 9e-09
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 60 9e-09
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 60 9e-09
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 60 1e-08
gi|71061468 centromere protein E [Homo sapiens] 60 1e-08
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 59 2e-08
gi|4504063 golgin 97 [Homo sapiens] 59 2e-08
gi|31982906 cingulin-like 1 [Homo sapiens] 59 2e-08
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 58 5e-08
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 58 5e-08
gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens] 57 6e-08
gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens] 57 6e-08
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 56 1e-07
gi|116686122 kinesin family member 4 [Homo sapiens] 56 1e-07
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 55 2e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens] 55 2e-07
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 55 3e-07
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 55 3e-07
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens] 55 4e-07
>gi|188497667 trafficking protein, kinesin binding 2 [Homo sapiens]
Length = 914
Score = 1795 bits (4648), Expect = 0.0
Identities = 914/914 (100%), Positives = 914/914 (100%)
Query: 1 MSQSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDT 60
MSQSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDT
Sbjct: 1 MSQSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDT 60
Query: 61 LFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLA 120
LFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLA
Sbjct: 61 LFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLA 120
Query: 121 ERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSI 180
ERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSI
Sbjct: 121 ERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSI 180
Query: 181 ASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVT 240
ASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVT
Sbjct: 181 ASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVT 240
Query: 241 YEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKE 300
YEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKE
Sbjct: 241 YEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKE 300
Query: 301 HVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHL 360
HVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHL
Sbjct: 301 HVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHL 360
Query: 361 YFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSIS 420
YFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSIS
Sbjct: 361 YFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSIS 420
Query: 421 FPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDS 480
FPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDS
Sbjct: 421 FPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDS 480
Query: 481 DLATALHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESLASLCTTQSE 540
DLATALHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESLASLCTTQSE
Sbjct: 481 DLATALHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESLASLCTTQSE 540
Query: 541 ITDLSSASCLRGFMPEKLQIVKPLEGSQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLP 600
ITDLSSASCLRGFMPEKLQIVKPLEGSQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLP
Sbjct: 541 ITDLSSASCLRGFMPEKLQIVKPLEGSQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLP 600
Query: 601 GDAIYHISDLEEDEEEGITFQVQQPLEVEEKLSTSKPVTGIFLPPITSAGGPVTVATANP 660
GDAIYHISDLEEDEEEGITFQVQQPLEVEEKLSTSKPVTGIFLPPITSAGGPVTVATANP
Sbjct: 601 GDAIYHISDLEEDEEEGITFQVQQPLEVEEKLSTSKPVTGIFLPPITSAGGPVTVATANP 660
Query: 661 GKCLSCTNSTFTFTTCRILHPSDITQVTPSSGFPSLSCGSSGSSSSNTAVNSPALSYRLS 720
GKCLSCTNSTFTFTTCRILHPSDITQVTPSSGFPSLSCGSSGSSSSNTAVNSPALSYRLS
Sbjct: 661 GKCLSCTNSTFTFTTCRILHPSDITQVTPSSGFPSLSCGSSGSSSSNTAVNSPALSYRLS 720
Query: 721 IGESITNRRDSTTTFSSTMSLAKLLQERGISAKVYHSPISENPLQPLPKSLAIPSTPPNS 780
IGESITNRRDSTTTFSSTMSLAKLLQERGISAKVYHSPISENPLQPLPKSLAIPSTPPNS
Sbjct: 721 IGESITNRRDSTTTFSSTMSLAKLLQERGISAKVYHSPISENPLQPLPKSLAIPSTPPNS 780
Query: 781 PSHSPCPSPLPFEPRVHLSENFLASRPAETFLQEMYGLRPSRNPPDVGQLKMNLVDRLKR 840
PSHSPCPSPLPFEPRVHLSENFLASRPAETFLQEMYGLRPSRNPPDVGQLKMNLVDRLKR
Sbjct: 781 PSHSPCPSPLPFEPRVHLSENFLASRPAETFLQEMYGLRPSRNPPDVGQLKMNLVDRLKR 840
Query: 841 LGIARVVKNPGAQENGRCQEAEIGPQKPDSAVYLNSGSSLLGGLRRNQSLPVIMGSFAAP 900
LGIARVVKNPGAQENGRCQEAEIGPQKPDSAVYLNSGSSLLGGLRRNQSLPVIMGSFAAP
Sbjct: 841 LGIARVVKNPGAQENGRCQEAEIGPQKPDSAVYLNSGSSLLGGLRRNQSLPVIMGSFAAP 900
Query: 901 VCTSSPKMGVLKED 914
VCTSSPKMGVLKED
Sbjct: 901 VCTSSPKMGVLKED 914
>gi|111074532 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 1 [Homo sapiens]
Length = 953
Score = 730 bits (1885), Expect = 0.0
Identities = 450/931 (48%), Positives = 588/931 (63%), Gaps = 79/931 (8%)
Query: 31 DVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEE 90
DVC++ DLPEVE++SLLEEQLP Y+L+ DT++ Y++ DW +P A+ L+ EE
Sbjct: 31 DVCNSTDLPEVEIISLLEEQLPHYKLRADTIYGYDHDDWLHTPLISPDANIDLTTEQIEE 90
Query: 91 TFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESL 150
T +Y +L +RV QMTKTYNDID VT LL E++RDLELAARIGQ+LLK+N L+E+NE L
Sbjct: 91 TLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELL 150
Query: 151 EEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQL 210
EEQ+ ++V+QL+HEL KDELL+ + A+EESE +S CSTPL+ NES S Q L
Sbjct: 151 EEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHL 210
Query: 211 EMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEEL 270
+ LQ+KLK+LEEEN+ LRS+A +KTET+TYEEKEQQLV+DCVKELR+ N Q++ ++EEL
Sbjct: 211 DSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEEL 270
Query: 271 SGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQ 330
+ K+++ R QEE++ LLSQIVDLQ K K +E EEL HL A+KDAQRQLT EL EL+
Sbjct: 271 AKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELE 330
Query: 331 DRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDE 390
D+ EC+ MLHE+QEE+K LR+++ P S G F +SLAAEIEGTMRK+L L+E
Sbjct: 331 DKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLGLFPMDSLAAEIEGTMRKELQLEE 390
Query: 391 ESSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVI------MTAKPFES 444
S QKRVF+TVR N + P+ + IPGSN+SS + + P S
Sbjct: 391 AES--PDITHQKRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSS 448
Query: 445 GLQQTEDKSLLNQGSSS----EEVAG-----SSQKMGQPGPSGDSDLATALHRLSLRRQN 495
+L+ ++S E A S+K G PG G DL TAL RLSLRR+N
Sbjct: 449 FYGSDIGNVVLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRREN 508
Query: 496 YLSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESLASLCTTQ--SEITDLSSAS-CLRG 552
YLSE++FF EE +RK+Q LA++ E SG +TPTES+ SL T SE T S S R
Sbjct: 509 YLSERRFFEEEQERKLQELAEKGELRSGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRS 568
Query: 553 FMPEKLQIVKPLEGSQTLYHWQQLAQPNLGTILDPRPGVITKGFTQLPG--DAIYHISDL 610
++PEKLQIVKPLEGS TL+HWQQLAQP+LG ILDPRPGV+TKGF L D +Y ++D
Sbjct: 569 YLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDF 628
Query: 611 EEDEEEGITFQVQQPLEVEEKLSTSKPVTGIFLPPITSAGGPVTVATANPGKCLSCTNST 670
EED+ + P +L+TS PV P TSA +PGKC+S TNST
Sbjct: 629 EEDDTGD---HISLP-----RLATSTPVQ----HPETSA--------HHPGKCMSQTNST 668
Query: 671 FTFTTCRILHPSD-ITQVTPS-SGFPSLSCGSSGSSSSNTAVNSPALSYRLSIGESITNR 728
FTFTTCRILHPSD +T+VTPS + P+ +CGS+ S +T V +P RLS+ ES TN
Sbjct: 669 FTFTTCRILHPSDELTRVTPSLNSAPTPACGST-SHLKSTPVATPCTPRRLSLAESFTNT 727
Query: 729 RDSTTTFSSTMSLAKLLQERGISAKVYHSPISENPLQP------LPKSLAIPSTPPNSPS 782
R+STTT S+++ L LL+ERGISA VY + + PK IPSTPPNSP
Sbjct: 728 RESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMAVIPSTPPNSPM 787
Query: 783 HSPCPSPLPFEPRVHLS--ENFLASRPAETFLQEM--YGLRPSRNPPDVGQLKMNLVDRL 838
+P SP FE + +NFLAS+PA + L+E+ +R S + DV +NLVD++
Sbjct: 788 QTPTSSPPSFEFKCTSPPYDNFLASKPASSILREVREKNVRSSESQTDVSVSNLNLVDKV 847
Query: 839 KRLGIARVVKNPGAQENGRCQEAE---IGPQKPDSAVYLN------------------SG 877
+R G+A+VV + A +E GP P A+ G
Sbjct: 848 RRFGVAKVVNSGRAHVPTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPTVTSAIGG 907
Query: 878 SSLLGGLRRNQSLPVIMGS---FAAPVCTSS 905
L G+RRN+S P ++GS APV +S
Sbjct: 908 LQLNSGIRRNRSFPTMVGSSMQMKAPVTLTS 938
>gi|45359873 OGT(O-Glc-NAc transferase)-interacting protein 106 KDa
isoform 2 [Homo sapiens]
Length = 686
Score = 516 bits (1329), Expect = e-146
Identities = 304/574 (52%), Positives = 384/574 (66%), Gaps = 33/574 (5%)
Query: 62 FLYENQDWTQSPHQRQH-ASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLA 120
F Y+ QD + P RQH D L VL E RV QMTKTYNDID VT LL
Sbjct: 13 FEYDCQDEERKPTHRQHDTQDLLEEVLCAE----------RVGQMTKTYNDIDAVTRLLE 62
Query: 121 ERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSI 180
E++RDLELAARIGQ+LLK+N L+E+NE LEEQ+ ++V+QL+HEL KDELL+ +
Sbjct: 63 EKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTS 122
Query: 181 ASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVT 240
A+EESE +S CSTPL+ NES S Q L+ LQ+KLK+LEEEN+ LRS+A +KTET+T
Sbjct: 123 AAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETIT 182
Query: 241 YEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKE 300
YEEKEQQLV+DCVKELR+ N Q++ ++EEL+ K+++ R QEE++ LLSQIVDLQ K K
Sbjct: 183 YEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKA 242
Query: 301 HVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHL 360
+E EEL HL A+KDAQRQLT EL EL+D+ EC+ MLHE+QEE+K LR+++ P
Sbjct: 243 CAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTS 302
Query: 361 YFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSIS 420
S G F +SLAAEIEGTMRK+L L+E S QKRVF+TVR N +
Sbjct: 303 RRYHSLGLFPMDSLAAEIEGTMRKELQLEEAES--PDITHQKRVFETVRNINQVVKQRSL 360
Query: 421 FPALLPIPGSNRSSVI------MTAKPFESGLQQTEDKSLLNQGSSS----EEVAG---- 466
P+ + IPGSN+SS + + P S +L+ ++S E A
Sbjct: 361 TPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGND 420
Query: 467 -SSQKMGQPGPSGDSDLATALHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEGVSGCV 525
S+K G PG G DL TAL RLSLRR+NYLSE++FF EE +RK+Q LA++ E SG +
Sbjct: 421 ERSKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAEKGELRSGSL 480
Query: 526 TPTESLASLCTTQ--SEITDLSSAS-CLRGFMPEKLQIVKPLEGSQTLYHWQQLAQPNLG 582
TPTES+ SL T SE T S S R ++PEKLQIVKPLEGS TL+HWQQLAQP+LG
Sbjct: 481 TPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLG 540
Query: 583 TILDPRPGVITKGFTQLPG--DAIYHISDLEEDE 614
ILDPRPGV+TKGF L D +Y ++D EED+
Sbjct: 541 GILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDD 574
>gi|120431738 huntingtin-associated protein 1 isoform 2 [Homo
sapiens]
Length = 619
Score = 127 bits (319), Expect = 5e-29
Identities = 80/234 (34%), Positives = 129/234 (55%), Gaps = 30/234 (12%)
Query: 118 LLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRI 177
++ +R+RDL AARIGQ+L+K+N VL E+N LE LG A +++ L+H++ +DELL++
Sbjct: 196 MVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQL 255
Query: 178 VSIASEESETDSS-------------------------CSTPLRFNESFSLSQ-GLLQLE 211
S + EE E + C P ++ L Q QLE
Sbjct: 256 YSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLE 315
Query: 212 MLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELS 271
LQEKL+ LEEEN LR +A + T E++EQ L+ +CV++ E + QM+ ++E L
Sbjct: 316 ALQEKLRLLEEENHQLREEASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLV 371
Query: 272 GKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTME 325
+ + R Q+E++ L +Q++ LQ + + + E E+L+ L + K+ Q QL E
Sbjct: 372 LRLENYERQQQEVARLQAQVLKLQQRCRMYGAETEKLQKQLASEKEIQMQLQEE 425
>gi|120431745 huntingtin-associated protein 1 isoform 4 [Homo
sapiens]
Length = 594
Score = 115 bits (287), Expect = 2e-25
Identities = 76/244 (31%), Positives = 129/244 (52%), Gaps = 31/244 (12%)
Query: 118 LLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRI 177
++ +R+RDL AARIGQ+L+K+N VL E+N LE LG A +++ L+H++ +DELL++
Sbjct: 196 MVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQL 255
Query: 178 VSIASEESETDSS-------------------------CSTPLRFNESFSLSQ-GLLQLE 211
S + EE E + C P ++ L Q QLE
Sbjct: 256 YSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLE 315
Query: 212 MLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELS 271
LQEKL+ LEEEN LR +A + T E++EQ L+ +CV++ E + QM+ ++E L
Sbjct: 316 ALQEKLRLLEEENHQLREEASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLV 371
Query: 272 GKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQD 331
+ + R Q+E++ L +Q++ LQ + + + + L + +R ++ ++ +
Sbjct: 372 LRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAEELRTSLRRMISDPVY-FME 430
Query: 332 RNME 335
RN E
Sbjct: 431 RNYE 434
>gi|120431743 huntingtin-associated protein 1 isoform 3 [Homo
sapiens]
Length = 602
Score = 115 bits (287), Expect = 2e-25
Identities = 76/244 (31%), Positives = 129/244 (52%), Gaps = 31/244 (12%)
Query: 118 LLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRI 177
++ +R+RDL AARIGQ+L+K+N VL E+N LE LG A +++ L+H++ +DELL++
Sbjct: 204 MVLQRERDLNTAARIGQSLVKQNSVLMEENSKLEALLGSAKEEILYLRHQVNLRDELLQL 263
Query: 178 VSIASEESETDSS-------------------------CSTPLRFNESFSLSQ-GLLQLE 211
S + EE E + C P ++ L Q QLE
Sbjct: 264 YSDSDEEDEDEEEEEEEKEAEEEQEEEEAEEDLQCAHPCDAPKLISQEALLHQHHCPQLE 323
Query: 212 MLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELS 271
LQEKL+ LEEEN LR +A + T E++EQ L+ +CV++ E + QM+ ++E L
Sbjct: 324 ALQEKLRLLEEENHQLREEASQLD----TLEDEEQMLILECVEQFSEASQQMAELSEVLV 379
Query: 272 GKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQD 331
+ + R Q+E++ L +Q++ LQ + + + + L + +R ++ ++ +
Sbjct: 380 LRLENYERQQQEVARLQAQVLKLQQRCRMETLPGFQETLAEELRTSLRRMISDPVY-FME 438
Query: 332 RNME 335
RN E
Sbjct: 439 RNYE 442
>gi|119120918 coiled-coil domain containing 64 [Homo sapiens]
Length = 573
Score = 71.2 bits (173), Expect = 4e-12
Identities = 93/349 (26%), Positives = 154/349 (44%), Gaps = 50/349 (14%)
Query: 118 LLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRI 177
++ ++++DL LAAR+G+ALL+RN +S Q E + ++L + + Q +HEL ++ E
Sbjct: 102 VIRQKEKDLVLAARLGKALLERNQDMSRQYEQMHKELTDKLEHLEQEKHELRRRFE---- 157
Query: 178 VSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTE 237
+ E E + S L + QL+ ELE + + LR +A K+
Sbjct: 158 ----NREGEWEGRVS---------ELESDVKQLQ------DELERQQIHLR-EADREKSR 197
Query: 238 TVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIV---DL 294
V ++ Q + D + E Q+S L + D ++E+ SS I+ L
Sbjct: 198 AVQELSEQNQRLLDQLSRASEVERQLSMQVHAL--RED----FREKNSSTNQHIIRLESL 251
Query: 295 QHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDR--NMECLG-----MLHESQEEI 347
Q ++K K EL+ L A+ + L + ELQDR +E G LH+SQ E+
Sbjct: 252 QAEIKMLSDRKRELEHRLSATLEENDLLQGTVEELQDRVLILERQGHDKDLQLHQSQLEL 311
Query: 348 KEL----RSRSGPTAHLYFSQSY--GAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQ 401
+E+ R L +S A T SL +EIE +M + E L + Q
Sbjct: 312 QEVRLSCRQLQVKVEELTEERSLQSSAATSTSLLSEIEQSMEAEELEQEREQL---RLQL 368
Query: 402 KRVFDTVR-IANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQT 449
+ VR + + RG + A+ + SS +AK +G +T
Sbjct: 369 WEAYCQVRYLCSHLRGNDSADSAVSTDSSMDESSETSSAKDVPAGSLRT 417
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 69.7 bits (169), Expect = 1e-11
Identities = 127/573 (22%), Positives = 241/573 (42%), Gaps = 72/573 (12%)
Query: 42 ELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDR 101
E VS L+ Q+ + K + L E Q + H A + + ++ I T +
Sbjct: 635 EKVSQLDIQI---KAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKI--TTQ 689
Query: 102 VEQMTKTYND-----IDMVTHLLAERDRDLELAARIGQ--ALLKRNHVLSEQNESLEEQL 154
++Q+T D + +HL +++ L L + + +K+ S + ++ +EQ
Sbjct: 690 LDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQA 749
Query: 155 GQAFDQVNQLQHELCKKDELLRIVSIASE-ESETDSSCSTPLRFNESFSLSQGLLQLEML 213
Q Q QL +L LR ++ + E E + ST L L + LE +
Sbjct: 750 LQDLQQQRQLNTDL-----ELRATELSKQLEMEKEIVSSTRL------DLQKKSEALESI 798
Query: 214 QEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGK 273
++KL + EEE L+ + ET E+ + V EL++ + + ELS
Sbjct: 799 KQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTV 858
Query: 274 SDELIRYQEELSSLLSQ-----------IVDLQHKLKE--HVI---------EKEELKLH 311
D+L + + L + S+ I+DL+ KE H + E++ELK
Sbjct: 859 KDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKS 918
Query: 312 LQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTG 371
L+ K+A QL +EL+ +Q++ ++ L ++++E ++L+ G L S
Sbjct: 919 LEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQ---GNINELKQSSEQKKKQI 975
Query: 372 ESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIA---NDTRGRSISFPALLPIP 428
E+L E++ + +K L+ + +A Q+ + +I+ N+ +F L
Sbjct: 976 EALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDF 1035
Query: 429 GSNRSSVIMTAKPFESGLQQTEDKSLLNQGS--SSEEVAGSSQKMGQPGPSGDSDLATA- 485
S ++ T L+ E+K L Q S+ G+ K+ Q +L TA
Sbjct: 1036 YGRESELLAT----RQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQ-------ELKTAK 1084
Query: 486 --LHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESLASLCTTQSEITD 543
L + S +++ L E+ ++ Q++ + +KE V+ E C + EIT
Sbjct: 1085 ATLEQDSAKKEQQLQERCKALQDIQKEKSL--KEKELVNEKSKLAEIEEIKCRQEKEITK 1142
Query: 544 LSSASCLRGFMPEKLQIVKPLEGSQTLYHWQQL 576
L+ L+ E ++ + L+ ++ L Q+L
Sbjct: 1143 LNEE--LKSHKLESIKEITNLKDAKQLLIQQKL 1173
Score = 52.8 bits (125), Expect = 1e-06
Identities = 84/369 (22%), Positives = 154/369 (41%), Gaps = 35/369 (9%)
Query: 146 QNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEES-ETDSSCSTPLRFNESFSLS 204
Q LE +L Q Q+ Q EL + E + ++ E+S ET + ES L+
Sbjct: 988 QKTELENKLQQ---QLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLA 1044
Query: 205 QGLLQLEMLQEKLKELEEENMALRSKACH-------IKTETVTYEE----KEQQLVSDCV 253
L+ ++EKL +E+ ++ R++ + +KT T E+ KEQQL C
Sbjct: 1045 TRQ-DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERC- 1102
Query: 254 KELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQ 313
K L++ + S +EL + +L +E +I L +LK H +E + +L+
Sbjct: 1103 KALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLK 1162
Query: 314 ASKDAQRQLTMELH----------ELQDRNMECL-GMLHESQEEIKELRSRSGPTAHLYF 362
+K Q +EL E + RN + L + + +EE+K+ H
Sbjct: 1163 DAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLH--- 1219
Query: 363 SQSYGAFTGESLAAEIEGTMRKKL-SLDEESSLFKQKAQ--QKRVFDTVRIANDTRGRSI 419
S+ G E E + ++ +L+E K++ Q Q+RV + + +D RG
Sbjct: 1220 SEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIA 1279
Query: 420 SFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGD 479
A + R +++ E +++ + K +L + + Q++G+ S
Sbjct: 1280 VLEATVQNNQDERRALLERCLKGEGEIEKLQTK-VLELQRKLDNTTAAVQELGRENQSLQ 1338
Query: 480 SDLATALHR 488
AL+R
Sbjct: 1339 IKHTQALNR 1347
Score = 48.1 bits (113), Expect = 4e-05
Identities = 82/407 (20%), Positives = 166/407 (40%), Gaps = 58/407 (14%)
Query: 42 ELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDR 101
E L+E+L + K L Q Q + QH S + +L T+R
Sbjct: 372 EATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEI---NQLHSKLLETER 428
Query: 102 VEQMTKTYNDIDMVTHLLAER--DRDLELA------ARIGQALLKR-------NHVLSEQ 146
Q+ + + + L +E+ D++ ++A +R+ + L ++ H L +
Sbjct: 429 --QLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKT 486
Query: 147 NESLEEQ----------LGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLR 196
+ +EQ L +A + + Q+ ++ KD+ ++ + ++S+ + S R
Sbjct: 487 KQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKER 546
Query: 197 FNESFSLSQG---LLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCV 253
+ + G L LQEK L+E+ L K +K ++ ++++ ++ L
Sbjct: 547 EDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEK---LKNQSESHKQAQENLHDQVQ 603
Query: 254 KELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVI---------E 304
++ A R+ L +EL E +SQ+ D+Q K K ++ +
Sbjct: 604 EQKAHLRAAQDRVL-SLETSVNELNSQLNESKEKVSQL-DIQIKAKTELLLSAEAAKTAQ 661
Query: 305 KEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQ 364
+ +L+ HL +++A + EL+++ + + L + QE +L S Y S
Sbjct: 662 RADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSL 721
Query: 365 SYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKA----QQKRVFDT 407
E E+EG ++K + E K++A QQ+R +T
Sbjct: 722 -------EQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNT 761
Score = 45.8 bits (107), Expect = 2e-04
Identities = 78/384 (20%), Positives = 169/384 (44%), Gaps = 34/384 (8%)
Query: 39 PEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPH-----QRQHAS-DALSPVLAEETF 92
P +E V++L+++L Q + +D + L ++ + Q Q+AS +A L E
Sbjct: 218 PGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELA 277
Query: 93 RYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEE 152
+ V+++ K + ++ +T +L + L ++++ S ++++
Sbjct: 278 KGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQA 337
Query: 153 QLGQAFDQVNQLQHELCKKDELLRIVSIA-SEESETDSSCSTPLRFNESFSLSQGLLQLE 211
L Q QLQ L + L + + SE+ E L E+ + +
Sbjct: 338 TLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVET-KYQHLKAEFK 396
Query: 212 MLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQL--VSDCVKELRETNAQ-MSRMTE 268
LQ++ +E E+ + L+S+ + ++ + E E+QL +KE R+ +++ + +
Sbjct: 397 QLQQQREEKEQHGLQLQSEINQLHSKLL---ETERQLGEAHGRLKEQRQLSSEKLMDKEQ 453
Query: 269 ELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQAS----KDAQRQLTM 324
+++ +L R +E+L ++ +LQH+L + + +E + Q++ ++AQ L
Sbjct: 454 QVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQ 513
Query: 325 ELHELQDR-----NMECLGMLHESQEEIKEL-RSRSGPTAHLYFSQSYGAFTGESLAAEI 378
L ++ D+ N+E L L +S+E I L + R A + GE A +
Sbjct: 514 VLRQIGDKDQKIQNLEAL--LQKSKENISLLEKEREDLYAKIQ--------AGEGETAVL 563
Query: 379 EGTMRKKLSLDEESSLFKQKAQQK 402
K +L E+ + +K + +
Sbjct: 564 NQLQEKNHTLQEQVTQLTEKLKNQ 587
Score = 36.6 bits (83), Expect = 0.11
Identities = 74/327 (22%), Positives = 118/327 (36%), Gaps = 41/327 (12%)
Query: 212 MLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVS-DCVKEL-------RETNAQM 263
+LQ + + L S A I T V E + + C+K L + A
Sbjct: 5 ILQRTPGRVGSQGSDLDSSATPINTVDVNNESSSEGFICPQCMKSLGSADELFKHYEAVH 64
Query: 264 SRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLT 323
+ G L +++++ L ++ DLQ LKE EELK L+
Sbjct: 65 DAGNDSGHGGESNLALKRDDVTLLRQEVQDLQASLKEEKWYSEELKKELE---------- 114
Query: 324 MELHELQDRNMECLGMLHESQEEIKELRSR--SGPTAHLYFSQSYGAFTGES--LAAEIE 379
+ LQ + + G++ +S E++ L + T + Q F ++ LA EI
Sbjct: 115 -KYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMKDLFEQKAAQLATEIA 173
Query: 380 GTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVI--- 436
K DEE SL ++ A+QK T + + LL PG +V+
Sbjct: 174 DI---KSKYDEERSL-REAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKE 229
Query: 437 ----------MT-AKPFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLATA 485
MT + ES + E K L +Q +SSE + GP +
Sbjct: 230 LVQVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQE 289
Query: 486 LHRLSLRRQNYLSEKQFFAEEWQRKIQ 512
L +L + Q E +K Q
Sbjct: 290 LQKLKSSVNELTQKNQTLTENLLKKEQ 316
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 66.2 bits (160), Expect = 1e-10
Identities = 119/561 (21%), Positives = 229/561 (40%), Gaps = 81/561 (14%)
Query: 8 IFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQ 67
+ T + +ENL N ++ E I+ E+E+++ E + Q + Q
Sbjct: 2387 VVTIRSEKENLTNELQKEQERIS---------ELEIINSSFENILQEK----------EQ 2427
Query: 68 DWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLE 127
+ Q + A + L L E R L D+ K N V L E+ + L+
Sbjct: 2428 EKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQ 2487
Query: 128 LAARIGQALLKRNHV--------LSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVS 179
G K N++ L ++ E +++L + +++++L++++ +++L+ +S
Sbjct: 2488 -----GLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLS 2542
Query: 180 IASEESETDSSCSTPLRFNESFSLSQGLLQLEM----LQEKLKELEEENMALRSKACHIK 235
E + + LR N + L Q + L+ LQ+ L+ L+ L ++ K
Sbjct: 2543 QVEGEHQLWKEQNLELR-NLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTK 2601
Query: 236 TETVTYEEKEQQLVS---DCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIV 292
+ +++ EK ++ + + +E+ E + + + EELSG+ + L EL LL +I
Sbjct: 2602 MDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAG---ELQLLLEEIK 2658
Query: 293 DLQHKLKEHVIEKEELKLHL------QASKDAQ-----RQLTMELHELQDRNMECLGMLH 341
+ +LKE +E ELK L Q K+ + + + LHE + ++ L +
Sbjct: 2659 SSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTN 2718
Query: 342 ESQE-EIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQ 400
+ E EI+ R + SQ +S E+ +++ + EE L K K
Sbjct: 2719 KQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEE--LKKTKMD 2776
Query: 401 QKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSS 460
+ + ++ N+ + +I + K E E+K +L + S
Sbjct: 2777 NLKYVNQLKKENERAQGKMKL-------------LIKSCKQLE------EEKEILQKELS 2817
Query: 461 SEEVAGSSQKMGQPGPSGDSDLATALHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEG 520
+ A QK G + +L T + L + L EK A+E+ K L E
Sbjct: 2818 QLQAAQEKQKTGTVMDTKVDELTTEIKEL----KETLEEKTKEADEYLDKYCSLLISHEK 2873
Query: 521 VSGCVTPTES-LASLCTTQSE 540
+ E+ +A LC+ QS+
Sbjct: 2874 LEKAKEMLETQVAHLCSQQSK 2894
Score = 53.9 bits (128), Expect = 7e-07
Identities = 99/466 (21%), Positives = 197/466 (42%), Gaps = 43/466 (9%)
Query: 127 ELAARIGQALLKRNHVLSEQNESLEEQLGQA-FDQVN---QLQHELCKKDELLRIVSIAS 182
EL +I Q L K +L +++ESL+ +L ++ ++++N L+ L +K E +S
Sbjct: 2053 ELENQIAQ-LNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQ 2111
Query: 183 EESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYE 242
EE LR + L + EKLKE E EN +L+ K +++ E E
Sbjct: 2112 EEVHQLRRGIEKLRVRIEADEKKQL----HIAEKLKERERENDSLKDKVENLERELQMSE 2167
Query: 243 EKEQQLVSDCVK---ELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLK 299
E ++ ++ D E+ Q+ M L +L+ + E +L QI + Q +L
Sbjct: 2168 ENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLS 2227
Query: 300 EHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAH 359
E ++L ++ + + Q +++ E +E L Q ++KEL A
Sbjct: 2228 ----ELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEML------QNQLKELNE---AVAA 2274
Query: 360 LYFSQSYGAFTGESLAAEIEGTMRKKLSLDE-----ESSLFKQKAQQKRVFDTVRIANDT 414
L Q T +SL IE + + S+++ E+ KQ +++ ++ A+
Sbjct: 2275 LCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLL 2334
Query: 415 RGRSISFPALLPIPGSNRSSVIMTAKPFESGLQ----QTEDKSLLNQGSSSEEVAGSSQK 470
+GR + L I +N+ + A+ + ++ + E + +G + V S+K
Sbjct: 2335 KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEK 2394
Query: 471 MGQPGP-SGDSDLATALHRLSLRRQNYLSEKQFFAEEWQRK----IQVLADQKEGVSGCV 525
+ + + L ++ +N L EK+ + + K +++L Q + ++ V
Sbjct: 2395 ENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERV 2454
Query: 526 TPTESLASLCTTQSEITDLSSASCLRGFMPEKLQIVKPLEGSQTLY 571
+ C + + S CL EK Q+++ L+ ++ Y
Sbjct: 2455 AALHNDQEACKAKEQNLS-SQVECLE---LEKAQLLQGLDEAKNNY 2496
Score = 48.9 bits (115), Expect = 2e-05
Identities = 51/237 (21%), Positives = 105/237 (44%), Gaps = 12/237 (5%)
Query: 100 DRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFD 159
D ++++ ++ + H + DLE+ L K N + LEE+L
Sbjct: 1899 DVENELSRIRSEKASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTS 1958
Query: 160 QVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKE 219
+ NQL+ EL D + + + + SE + L ++ S+ L +++ + ++KE
Sbjct: 1959 ERNQLRGEL---DTMSKKTTALDQLSEKMKEKTQELESHQ----SECLHCIQVAEAEVKE 2011
Query: 220 LEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIR 279
E L S + + +EK Q L D + L T ++ +L+ + + L++
Sbjct: 2012 KTELLQTLSSDVSELLKDKTHLQEKLQSLEKDS-QALSLTKCELENQIAQLNKEKELLVK 2070
Query: 280 YQEELSSLLSQI----VDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDR 332
E L + LS+ +++ L+ ++EK E L L ++++ QL + +L+ R
Sbjct: 2071 ESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVR 2127
Score = 45.4 bits (106), Expect = 2e-04
Identities = 63/273 (23%), Positives = 112/273 (41%), Gaps = 35/273 (12%)
Query: 101 RVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQ 160
RVE +D++M + D IG + K N E+ +E +L + +
Sbjct: 1859 RVETSEGLNSDLEMHADKSSRED--------IGDNVAKVNDSWKERFLDVENELSRIRSE 1910
Query: 161 VNQLQHE---------------LCKK---DELLRIVSIASEESETDSSCSTPLRFNESFS 202
++HE LC + + +++ EE +S LR E +
Sbjct: 1911 KASIEHEALYLEADLEVVQTEKLCLEKDNENKQKVIVCLEEELSVVTSERNQLR-GELDT 1969
Query: 203 LSQGLLQLEMLQEKLKELEEENMALRSKACH-IKTETVTYEEKEQ--QLVSDCVKELRET 259
+S+ L+ L EK+KE +E + +S+ H I+ +EK + Q +S V EL +
Sbjct: 1970 MSKKTTALDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKD 2029
Query: 260 NAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVI-EKEELKLHLQASKDA 318
+ + L S L + EL + ++Q+ +K KE ++ E E L+ L S
Sbjct: 2030 KTHLQEKLQSLEKDSQALSLTKCELENQIAQL----NKEKELLVKESESLQARLSESDYE 2085
Query: 319 QRQLTMELHELQDRNMECLGMLHESQEEIKELR 351
+ ++ L E L +QEE+ +LR
Sbjct: 2086 KLNVSKALEAALVEKGEFALRLSSTQEEVHQLR 2118
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/221 (19%), Positives = 94/221 (42%), Gaps = 23/221 (10%)
Query: 145 EQNESLEEQLGQAF-----DQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNE 199
E+N EQ+ Q+F ++++LQ + ++ A E E + E
Sbjct: 864 EENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETE 923
Query: 200 SFSLSQGLLQLEMLQEKLKELE--EENMALRSKACHIKTETVTYEEKEQQLVSDCVKELR 257
+ + +L++ LKEL+ E ++L K + ++ ++E + ++ L+
Sbjct: 924 QAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEM---SSIISLNKREIEELTQENGTLK 980
Query: 258 ETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKD 317
E NA +++ L KS+ Y +E +S++ D ++ EK L + + +
Sbjct: 981 EINASLNQEKMNLIQKSESFANYIDEREKSISELSD------QYKQEKLILLQRCEETGN 1034
Query: 318 AQRQLTMELHELQDRNM-------ECLGMLHESQEEIKELR 351
A L+ + Q++N EC + + E+++L+
Sbjct: 1035 AYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLK 1075
Score = 41.2 bits (95), Expect = 0.004
Identities = 56/269 (20%), Positives = 105/269 (39%), Gaps = 50/269 (18%)
Query: 165 QHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEEN 224
+ E+ L+I + S D+S S L L Q Q + L+ K+ ELE
Sbjct: 249 EQEVTPSRSTLQIGKRDANSSFFDNSSSPHL-------LDQLKAQNQELRNKINELE--- 298
Query: 225 MALRSKACHIKTETVTYEEKEQQL-------------VSDCVKELRETNAQMSRMTEELS 271
+ L+ +K + ++E + QL ++ C EL T AQ + + + +
Sbjct: 299 LRLQGHEKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYT 358
Query: 272 GKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQD 331
+L + E+LS + L++ + EKE K+ Q +L+ + Q
Sbjct: 359 ALEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKE---------KEFQEELSRQQRSFQT 409
Query: 332 RNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEE 391
+ EC+ M +E+++ ++ L AE++ K L+
Sbjct: 410 LDQECIQMKARLTQELQQAKNMH-----------------NVLQAELDKLTSVKQQLENN 452
Query: 392 SSLFKQK-AQQKRVFDTVRIANDTRGRSI 419
FKQK + ++ F +I + RS+
Sbjct: 453 LEEFKQKLCRAEQAFQASQIKENELRRSM 481
Score = 36.2 bits (82), Expect = 0.14
Identities = 54/223 (24%), Positives = 91/223 (40%), Gaps = 43/223 (19%)
Query: 125 DLELAARIGQALLK-RNHVLSEQNESLEEQ------LGQAFDQVNQLQHEL--------C 169
DLE Q LLK R H + + N+ L + L A + + EL C
Sbjct: 562 DLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSC 621
Query: 170 KKDELLRIVSIASEESETDSS----CSTPLRFNE--SFSLSQGLLQLEMLQEKLK-ELEE 222
K E ++++ E E S T L+ + S ++ + LEM +E L E+
Sbjct: 622 WKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRN 681
Query: 223 ENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQE 282
+ L SK+ ++T+ + Y E +Q+ K +E M T +L+G
Sbjct: 682 LHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIE-NMCLKTSQLTG---------- 730
Query: 283 ELSSLLSQIVDLQHKLK---EHVIEKEELKLHLQASKDAQRQL 322
Q+ DL+HKL+ +++K+ L A ++ R L
Sbjct: 731 -------QVEDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDL 766
Score = 35.4 bits (80), Expect = 0.24
Identities = 47/212 (22%), Positives = 92/212 (43%), Gaps = 23/212 (10%)
Query: 134 QALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCK-KDELLRIVSIASEESETDSSCS 192
Q L + + L + + E+++ ++ +LQ +L K K EL+ E+ + + C
Sbjct: 288 QELRNKINELELRLQGHEKEMKGQVNKFQELQLQLEKAKVELI-------EKEKVLNKCR 340
Query: 193 TPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKA----CHIKTETVTYEEKEQQL 248
L + Q + L++KLK+L E+ R A C ++ + +EKE++
Sbjct: 341 DEL-VRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKI---KEKEKEF 396
Query: 249 VSDCVKELR-------ETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEH 301
+ ++ R E +R+T+EL + Q EL L S L++ L+E
Sbjct: 397 QEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEF 456
Query: 302 VIEKEELKLHLQASKDAQRQLTMELHELQDRN 333
+ + QAS+ + +L + E++ N
Sbjct: 457 KQKLCRAEQAFQASQIKENELRRSMEEMKKEN 488
Score = 33.5 bits (75), Expect = 0.93
Identities = 45/220 (20%), Positives = 94/220 (42%), Gaps = 25/220 (11%)
Query: 126 LELAARIGQALLKR---NHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIAS 182
+++ AR+ Q L + ++VL + + L Q + + + + +LC+ ++ + I
Sbjct: 415 IQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKE 474
Query: 183 EE---SETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKEL--EEENMALRSKACHIKTE 237
E S + L + S ++ + LE + +K+ + +N A KA + E
Sbjct: 475 NELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQE 534
Query: 238 TVTYE--------------EKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEE 283
T+ + EK + V+D K+ + + + + +D+L + ++E
Sbjct: 535 TMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKE 594
Query: 284 LSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLT 323
+LLS L+ K KE+ KEE L + ++ LT
Sbjct: 595 SKALLSA---LELKKKEYEELKEEKTLFSCWKSENEKLLT 631
Score = 31.6 bits (70), Expect = 3.5
Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 22/145 (15%)
Query: 204 SQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQM 263
SQG+++ + +QE + L E L ++ + ++ E+ QQ ++ E+ A
Sbjct: 1572 SQGIMKNKEIQELEQLLSSERQELDC----LRKQYLSENEQWQQKLTSVTLEMESKLAAE 1627
Query: 264 SRMTEELSGKSDELIRYQ---EELSSLLSQIVDLQHKL----------KEHVIEKEEL-- 308
+ TE+LS + E+ R Q +LSS +D + + KEH E E
Sbjct: 1628 KKQTEQLSLEL-EVARLQLQGLDLSSRSLLGIDTEDAIQGRNESCDISKEHTSETTERTP 1686
Query: 309 --KLHLQASKDAQRQLTMELHELQD 331
+H KDAQ+ L +++ ++ +
Sbjct: 1687 KHDVHQICDKDAQQDLNLDIEKITE 1711
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 62.8 bits (151), Expect = 1e-09
Identities = 102/470 (21%), Positives = 194/470 (41%), Gaps = 44/470 (9%)
Query: 117 HLLAERDRDLELAARIGQA---LLKRNHVLSEQN-ESLEEQLGQAFDQVNQLQHELCKKD 172
HL+ + +++++L A LLK+ H LS S+ E+L Q V QL+ +L ++
Sbjct: 468 HLVNDYEQNMKLLQTKYDADINLLKQEHALSASKASSMIEELEQ---NVCQLKQQL-QES 523
Query: 173 ELLRIVSIASEES--ETDSSCSTPLRFNESFSLSQGL--------LQLEMLQEKLKELEE 222
EL R + +E+ + + S + ++ L L ++ +E LKE EE
Sbjct: 524 ELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEE 583
Query: 223 E-NMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQ 281
+ + + EE ++Q+ + K E QM ++ +L+ +S L Q
Sbjct: 584 QLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLT-RSKSLREKQ 642
Query: 282 EELSSLLSQIVDLQHKLKEHVIE----KEELKLHLQASKDAQRQLTMELHELQDRNME-- 335
+ L Q+ D++ + ++ ++E E+ K HL +A++ + HE + N+E
Sbjct: 643 SK--EFLWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQ 700
Query: 336 --CLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESS 393
M HE+Q I+E + R +Q + L E+ ++ E
Sbjct: 701 LRAANMEHENQ--IQEFKKRDAQVIADMEAQVH------KLREELINVNSQRKQQLVELG 752
Query: 394 LFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKS 453
L +++ +Q+ + + N + S + + ++ + MT + S L+Q E +
Sbjct: 753 LLREEEKQRATREHEIVVNKLKAESEKMK--IELKKTHAAETEMTLEKANSKLKQIEKEY 810
Query: 454 LLNQGSSSEEVAGSSQKMGQPGPSGDSDLATALHRLSLRRQNYLSEKQFFAEEWQRKIQV 513
SS+ +A + A RL RQ + EK+ + + I+V
Sbjct: 811 TQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKV 870
Query: 514 LADQKEGVSGCVTPTESLA--SLCTTQSEITDLSS--ASCLRGFMPEKLQ 559
L D+ E S V E +Q +IT + + L+G MP L+
Sbjct: 871 LQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLR 920
Score = 39.7 bits (91), Expect = 0.013
Identities = 24/98 (24%), Positives = 48/98 (48%)
Query: 256 LRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQAS 315
LR+ +S MT + S + LS + + +D++ K+ E +E+LKL +
Sbjct: 221 LRQKPIPVSLMTPKFSLRKSSSFHDDHFLSRIREKELDMKTKMMEAKFHEEKLKLQQKHD 280
Query: 316 KDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSR 353
D Q+ L + +E+++ HE++E I++L +
Sbjct: 281 ADVQKILERKNNEIEELKTLYRSKQHETEETIRKLEKK 318
Score = 38.9 bits (89), Expect = 0.022
Identities = 43/152 (28%), Positives = 66/152 (43%), Gaps = 29/152 (19%)
Query: 211 EMLQEKLKELEEENMALRSKACHIKTETVT-YEEKEQQLVSDCVKELRETNAQMSRMTEE 269
++L+ K E+EE RSK H ET+ E+K Q L+ DC + +RET ++
Sbjct: 285 KILERKNNEIEELKTLYRSKQ-HETEETIRKLEKKVQTLIRDC-QVIRETKEDQIAELKK 342
Query: 270 LSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHE- 328
+ +S E + D + KL V E E+ K D Q+Q T + E
Sbjct: 343 ICEQSTESLNN------------DWEKKLHNAVAEMEQEKF------DLQKQHTENIQEL 384
Query: 329 LQDRNM-------ECLGMLHESQEEIKELRSR 353
L+D N+ E + + IKEL +R
Sbjct: 385 LEDTNVRLNKMESEYMAQTQSTNHMIKELEAR 416
Score = 36.2 bits (82), Expect = 0.14
Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 8/138 (5%)
Query: 217 LKELEEENMALRSKACHIKTETVT--YEEKEQQLVSDCVKELRETNAQMSRMTEELSGKS 274
++E +E+ +A K C TE++ +E+K V++ +E + Q + +EL
Sbjct: 329 IRETKEDQIAELKKICEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQELL--E 386
Query: 275 DELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNM 334
D +R + S ++Q H +KE ++L + S +++L E EL+
Sbjct: 387 DTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELE---- 442
Query: 335 ECLGMLHESQEEIKELRS 352
C + +E+K R+
Sbjct: 443 RCYQITCSELQEVKARRN 460
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 60.5 bits (145), Expect = 7e-09
Identities = 72/282 (25%), Positives = 127/282 (45%), Gaps = 33/282 (11%)
Query: 145 EQNESLEEQLGQAFDQVNQLQHELCK-KDELLRIVSIASEESETDSSCSTP-----LRFN 198
EQNE+ + GQ QV +LC KD LL + I S + + +S TP LR +
Sbjct: 1275 EQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSS-ASLLTPQSAECLRAS 1333
Query: 199 ESFSLSQG--LLQLEMLQEKLKELEEENMALRS------KACHIKTETVTYEEKEQQLVS 250
+S LS+ LLQ E L+E K L+E++ +R+ + T E KE +
Sbjct: 1334 KSEVLSESSELLQQE-LEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTD 1392
Query: 251 DCVKELRETNAQMSRMTEE----LSGKSDELIRYQEELSSLLSQIVDLQH---KLKEHVI 303
+K+L+E + ++ +E + KSD+L+ E ++ +++ L+ LKE ++
Sbjct: 1393 SEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERIL 1452
Query: 304 EKE----ELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAH 359
E +LK + + R E LQ+ NM+ ML E + E ++ ++
Sbjct: 1453 ILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQ 1512
Query: 360 LYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQ 401
L + G E+ + S+ E++ +F+Q+ Q
Sbjct: 1513 LLKEKEQGK------TGELNQLLNAVKSMQEKTVVFQQERDQ 1548
Score = 55.8 bits (133), Expect = 2e-07
Identities = 137/657 (20%), Positives = 266/657 (40%), Gaps = 84/657 (12%)
Query: 16 ENLMNSNHRDSESITDVCSNEDL---PEVELVSLLEEQLPQYR--LKVDTLFLYENQDWT 70
+++++S+ + + +T + + +++ E S L+E+L +Y L+ + + ++
Sbjct: 793 KDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKD 852
Query: 71 QS----PHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDL 126
+S + H + L + E++ + ++ +T+ +++ + + + ++
Sbjct: 853 RSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEI 912
Query: 127 ELAARI----GQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHEL-CKKDELLRIVSIA 181
+ +I Q+ ++ L EQ + ++E Q +Q+N +L +KDE ++ +
Sbjct: 913 KHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQ-HEQMNATHTQLFLEKDEEIKSLQKT 971
Query: 182 SEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTY 241
E+ +T ++ + Q + K++ L EN + + +TE +
Sbjct: 972 IEQIKTQLHEERQDIQTDNSDIFQ--------ETKVQSLNIENGSEKHDLSKAETERLVK 1023
Query: 242 EEKEQQLVSDCVKELRETNAQMSRMTEELS----GKSDELIRYQE-ELSSLLSQI----- 291
KE++L +K L E N +++ ++LS GK ++I+ ++ E+ +L ++I
Sbjct: 1024 GIKERELE---IKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSH 1080
Query: 292 ----VDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEI 347
V LQ +L+ + +E+E++ L L E H++ D L + Q+E
Sbjct: 1081 TQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDEN 1140
Query: 348 KELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQ-KRVFD 406
K+L +R + F ++ I+ R D E QK Q V
Sbjct: 1141 KKLSTRFESSGQDMFRET------------IQNLSRIIREKDIEIDALSQKCQTLLAVLQ 1188
Query: 407 TVRIANDTRG-RSISFPALLPIPGSNRSSVIMTAKPFESGLQQ--TEDKSLLNQGSSSEE 463
T N+ G S F LL R + K E QQ T +++ ++ + +E
Sbjct: 1189 TSSTGNEAGGVNSNQFEELL----QERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQE 1244
Query: 464 VAGSSQKMGQPGPSGDSDLATALHRL-SLRRQNYLSEKQFFAE--EWQRKIQVLADQKE- 519
Q +S L L QN K F E + Q I L + K+
Sbjct: 1245 ELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDL 1304
Query: 520 --GVSGCVTPTESLASLCTTQSEITDLSSASCLRGFMPEKLQIVKPLEGSQTLYHWQQLA 577
G ++P S ASL T Q SA CLR E L E S+ L Q+L
Sbjct: 1305 LLGKLDIISPQLSSASLLTPQ-------SAECLRASKSEVLS-----ESSELLQ--QELE 1350
Query: 578 QPNLGTILDPRPGVI--TKGFTQLPGDAIYHISDLEEDEEEGITFQVQQPLEVEEKL 632
+ L L + I + D+I S+LE E E +++Q E ++ L
Sbjct: 1351 E--LRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVL 1405
Score = 47.4 bits (111), Expect = 6e-05
Identities = 50/259 (19%), Positives = 119/259 (45%), Gaps = 14/259 (5%)
Query: 100 DRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQ--ALLKRNHVLSEQNESLEEQLGQA 157
+R+ + + ++ + L++ + ++ + + Q +L + N L + E LE++
Sbjct: 375 ERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLL 434
Query: 158 FDQVNQLQHELCKKDELLRIV-SIASEESETDSSCSTPLRFN---ESFSLSQGLLQLEML 213
+ +LQ L K + ++ S A+ + DS LR N + L+Q + + E L
Sbjct: 435 SQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHD-LRLNLEAKEQELNQSISEKETL 493
Query: 214 QEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGK 273
+++EL+ +N IK + + + ++S ++L + ++ ++ ++
Sbjct: 494 IAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDI 553
Query: 274 SDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRN 333
+ EL +E+L + DL H K+ + +K E L Q +K + ++ +Q N
Sbjct: 554 TKELDVQKEKLIQSEVALNDL-HLTKQKLEDKVE-NLVDQLNKSQESNVS-----IQKEN 606
Query: 334 MECLGMLHESQEEIKELRS 352
+E + +++EE+ +R+
Sbjct: 607 LELKEHIRQNEEELSRIRN 625
Score = 37.7 bits (86), Expect = 0.049
Identities = 55/246 (22%), Positives = 106/246 (43%), Gaps = 25/246 (10%)
Query: 121 ERDRDLELAARIGQALLK-RNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVS 179
+R RD E R Q L + RNH+L ++ E L A D+ +L+ ++ +E L S
Sbjct: 1568 QRLRDKEF--RSNQELERLRNHLLESEDSYTREALA-AEDREAKLRKKVTVLEEKLVSSS 1624
Query: 180 IASEESETDSSCSTPLRFNE----SFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIK 235
A E + +S + S + LQL + QE++K+ L+ H
Sbjct: 1625 NAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEH-- 1682
Query: 236 TETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQ 295
++++E+ + S +++ ++ A+ + E L GK L +E ++ L L
Sbjct: 1683 -----FQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLT 1737
Query: 296 HKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSG 355
+L + EELK Q +L E+ L D + + + + S+ ++ ++ R+
Sbjct: 1738 EQLDVKEEQIEELK--------RQNELRQEM--LDDVQKKLMSLANSSEGKVDKVLMRNL 1787
Query: 356 PTAHLY 361
H +
Sbjct: 1788 FIGHFH 1793
Score = 37.0 bits (84), Expect = 0.084
Identities = 38/159 (23%), Positives = 71/159 (44%), Gaps = 18/159 (11%)
Query: 209 QLEMLQEKLKEL-------EEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNA 261
++E L++K+K++ E + LR + + E E+ + L +C K
Sbjct: 307 KMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVK 366
Query: 262 QMSRMTEE-----LSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKL--HLQA 314
Q MTE+ S +E+ R Q+ LS ++I+ L +++ + ++ LKL ++
Sbjct: 367 QSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEV 426
Query: 315 SKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSR 353
+ + L+ E ELQ L L+ E IK +R
Sbjct: 427 LEKEKSLLSQEKEELQ----MSLLKLNNEYEVIKSTATR 461
Score = 32.3 bits (72), Expect = 2.1
Identities = 44/228 (19%), Positives = 105/228 (46%), Gaps = 23/228 (10%)
Query: 103 EQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNE--SLEEQLGQAFDQ 160
+++ ++ ++ + + + E DR + A + +L ++ + +QNE S+ +L Q +
Sbjct: 481 QELNQSISEKETLIAEIEELDRQNQEATK--HMILIKDQLSKQQNEGDSIISKLKQDLND 538
Query: 161 VNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLL-QLEMLQEKLKE 219
+ H+L +D+ + I + E + + N+ Q L ++E L ++L +
Sbjct: 539 EKKRVHQL--EDDKMDITKELDVQKE--KLIQSEVALNDLHLTKQKLEDKVENLVDQLNK 594
Query: 220 LEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIR 279
+E N++++ + +K EE+ ++ ++ ++ L + + S D L++
Sbjct: 595 SQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQ---------DSNSNFKDTLLK 645
Query: 280 YQE----ELSSLLSQIVDLQHKLKEHVIE-KEELKLHLQASKDAQRQL 322
+E L LS++ L LK+ + K E + + A +D + QL
Sbjct: 646 EREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQL 693
>gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo
sapiens]
Length = 460
Score = 60.1 bits (144), Expect = 9e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 28/262 (10%)
Query: 136 LLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPL 195
L K EQ+ L ++ Q + N L+ +L K++ LR + EE+ +
Sbjct: 180 LEKDTAATGEQHSRLRQENLQLVHRANALEEQL--KEQELRACEMVLEETRRQKELLCKM 237
Query: 196 RFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQL---VSDC 252
+S +++E LQ +L++L+EEN LRS +K EE++Q+L +
Sbjct: 238 EREKS-------IEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESL 290
Query: 253 VKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEE----- 307
L E RM + LS + + R +E L+ + L+ +E E+
Sbjct: 291 TLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRS 350
Query: 308 --LKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIK-ELRSRSGPTAHLYFSQ 364
+ L S+ + +L E+ L+ N L E EE+ ++ + S A FS
Sbjct: 351 SSMGLQEYHSRARESELEQEVRRLKQDNRN----LKEQNEELNGQIITLSIQGAKSLFST 406
Query: 365 SYGAFTGESLAAEIEGTMRKKL 386
++ ESLAAEI R +L
Sbjct: 407 AF----SESLAAEISSVSRDEL 424
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 60.1 bits (144), Expect = 9e-09
Identities = 66/262 (25%), Positives = 112/262 (42%), Gaps = 28/262 (10%)
Query: 136 LLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPL 195
L K EQ+ L ++ Q + N L+ +L K++ LR + EE+ +
Sbjct: 476 LEKDTAATGEQHSRLRQENLQLVHRANALEEQL--KEQELRACEMVLEETRRQKELLCKM 533
Query: 196 RFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQL---VSDC 252
+S +++E LQ +L++L+EEN LRS +K EE++Q+L +
Sbjct: 534 EREKS-------IEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESL 586
Query: 253 VKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEE----- 307
L E RM + LS + + R +E L+ + L+ +E E+
Sbjct: 587 TLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRS 646
Query: 308 --LKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIK-ELRSRSGPTAHLYFSQ 364
+ L S+ + +L E+ L+ N L E EE+ ++ + S A FS
Sbjct: 647 SSMGLQEYHSRARESELEQEVRRLKQDNRN----LKEQNEELNGQIITLSIQGAKSLFST 702
Query: 365 SYGAFTGESLAAEIEGTMRKKL 386
++ ESLAAEI R +L
Sbjct: 703 AF----SESLAAEISSVSRDEL 720
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 60.1 bits (144), Expect = 9e-09
Identities = 88/384 (22%), Positives = 158/384 (41%), Gaps = 51/384 (13%)
Query: 16 ENLMNSNHRDSESITDVCSNEDL---PEVELVSLLEEQLPQYRLKVDTLFL--------- 63
E ++ HRD+ + ED+ P EL L E+Q YR ++ L L
Sbjct: 121 EKVLRVLHRDAILAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLLLAEKCHRRTV 180
Query: 64 YENQDWTQSPHQRQHASDALSPVLAEETFRYM-ILGTDRVEQMTKTYNDIDMVTHLLAER 122
YE ++ + SD + +L +E R +L ++ Q K + + L
Sbjct: 181 YELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNKL---- 236
Query: 123 DRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIAS 182
RD EL AL+ L ++ + EQLG +V L +L +++E L+ ++ S
Sbjct: 237 -RD-ELVKLKSFALM-----LVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITSKS 289
Query: 183 EESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYE 242
+E D L + S+ + E + KL E N LR K +
Sbjct: 290 KE---DRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQR----- 341
Query: 243 EKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHV 302
++EL ETN + + EEL D++ + + SSL++++ +L+ ++ E
Sbjct: 342 ----------IEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEVENLRKRVLEME 391
Query: 303 IEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYF 362
+ EE+ ++ +++L E H ++ +E + L + E+++L F
Sbjct: 392 GKDEEITKTESQCRELRKKLQEEEHHSKELRLE-VEKLQKRMSELEKLEEA--------F 442
Query: 363 SQSYGAFTGESLAAEIEGTMRKKL 386
S+S T L E E + K L
Sbjct: 443 SKSKSECTQLHLNLEKEKNLTKDL 466
Score = 44.7 bits (104), Expect = 4e-04
Identities = 76/371 (20%), Positives = 167/371 (45%), Gaps = 58/371 (15%)
Query: 26 SESITDVCSN--EDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDAL 83
S+ + D+ E+ +++ ++ ++ Q LK++ F ++ ++Q H+ +A A
Sbjct: 265 SQKVQDLTQKLREEEEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQE-HEEMNAKLA- 322
Query: 84 SPVLAEETFRYMILG-TDRVEQMTKTYNDIDMVTHLLAE-RDR-------DLELAARIGQ 134
+ R ++G T R+E++ +T ++ L E RD+ + L A + +
Sbjct: 323 NQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEV-E 381
Query: 135 ALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDEL-LRIVSIASEESETD----- 188
L KR + ++E + + Q + +LQ E EL L + + SE +
Sbjct: 382 NLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEKLQKRMSELEKLEEA 441
Query: 189 -----SSCST-PLRFNESFSLSQGLL-QLEMLQEKLKELE-------EENMALRSKACHI 234
S C+ L + +L++ LL +LE+++ ++KELE + ++L+ +
Sbjct: 442 FSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLEKAELSLKDDLTKL 501
Query: 235 KTETVTYEEKEQQLVSDCVKELRETNA----------QMSRMTEELSGKSDELIRYQEEL 284
K+ TV ++ + ++ +E R+ + ++ +TE+L +S +L++ + E
Sbjct: 502 KSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKSE- 560
Query: 285 SSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQ 344
++ K+ E++EL L++ ++ +L+ + L+ R L + E +
Sbjct: 561 ---------MEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKR----LDGIEEVE 607
Query: 345 EEIKELRSRSG 355
EI RSR G
Sbjct: 608 REITRGRSRKG 618
Score = 37.4 bits (85), Expect = 0.064
Identities = 50/238 (21%), Positives = 106/238 (44%), Gaps = 35/238 (14%)
Query: 112 IDMVTHLLAERDRDLELAARIGQA---LLKRNHVLSEQNESLEEQLGQAFDQVNQLQHEL 168
+D+ L+ E + L+L + + + L + L + +S EE+ + V+ L+ L
Sbjct: 541 MDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRL 600
Query: 169 CKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALR 228
+E+ R ++ ++ +C E + + L++E L+++L++LE L
Sbjct: 601 DGIEEVEREITRGRSRKGSELTCP------EDNKIKELTLEIERLKKRLQQLEVVEGDL- 653
Query: 229 SKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQE-ELSSL 287
+KTE Y++ EQ+ R + + ++++L ++ + + E +
Sbjct: 654 -----MKTED-EYDQLEQKF--------RTEQDKANFLSQQLEEIKHQIAKNKAIEKGEV 699
Query: 288 LSQIVDLQHKLKEHVIEKEELKLHLQASK----------DAQRQLTMELHELQDRNME 335
+SQ +L+H+ + + +LK +QA K D QL ++ LQ R ME
Sbjct: 700 VSQEAELRHRFRLEEAKSRDLKAEVQALKEKIHELMNKEDQLSQLQVDYSVLQQRFME 757
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 59.7 bits (143), Expect = 1e-08
Identities = 109/463 (23%), Positives = 196/463 (42%), Gaps = 63/463 (13%)
Query: 47 LEEQLPQYRLKVD----TLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRV 102
L E+ + RL+ + +LF + Q + Q ++ + +LA+ET + G
Sbjct: 895 LSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLR-- 952
Query: 103 EQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQN-ESLEEQLGQAFDQV 161
+Q+ T + L+A++ L A R QA L+ E++ + L+ + A+ ++
Sbjct: 953 QQIIATQEKASLDKELMAQK---LVQAEREAQASLREQRAAHEEDLQRLQREKEAAWREL 1009
Query: 162 N----QLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQ--LEMLQE 215
QLQ +L ++ E L A +E ++ + +E L++ Q L + +
Sbjct: 1010 EAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSLKES 1069
Query: 216 KLKELEEENMALRSKACHI-------KTETVTYEEKEQQLVSDCVKELRETNAQMSRMTE 268
+ L E+ M R I K + + +E+++ V+ ELR+ AQ E
Sbjct: 1070 EKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQRE---E 1126
Query: 269 ELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHE 328
+ + E+ R QE Q DL + + E EEL+ L+ +DA+ L EL E
Sbjct: 1127 AAAAHAQEVRRLQE-------QARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLE 1179
Query: 329 LQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSL 388
Q + L ESQE + R +G L S GA E+L
Sbjct: 1180 AQRK-------LRESQEGREVQRQEAG---ELRRSLGEGAKEREALRRS----------- 1218
Query: 389 DEESSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQ 448
+EE +KA+ +R+ ++++AN+ + + + ALL R++V A +GLQ+
Sbjct: 1219 NEELRSAVKKAESERI--SLKLANEDKEQKL---ALLE---EARTAVGKEAGELRTGLQE 1270
Query: 449 TEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLATALHRLSL 491
E +S L +E+ + + +LA RL+L
Sbjct: 1271 VE-RSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLAL 1312
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/259 (23%), Positives = 108/259 (41%), Gaps = 36/259 (13%)
Query: 121 ERDRDLELAARIGQALLKRNHVLSEQ-NESLEEQLGQAFDQVNQLQHELCKKDELL---- 175
ER +L L + + L+ + ++EQ E+LE+QL + +QLQ +L + L
Sbjct: 788 ERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGRE 847
Query: 176 -RIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEM---------LQEKLKELEEENM 225
+ E + R E+ + L +++ L E+ L E
Sbjct: 848 QELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATRLRLEKE 907
Query: 226 ALRSKACHIKTETVTYEEKEQQLVSD--CVKELRETNAQMSRMTEELSGKSDELIRYQEE 283
AL ++ + E + +QL ++ + +ET +T EL+G ++I QE+
Sbjct: 908 ALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET------LTGELAGLRQQIIATQEK 961
Query: 284 LS---SLLSQIV-----DLQHKLKEHVIEKEELKLHLQASKDAQ-RQLTMELHELQDR-- 332
S L++Q + + Q L+E EE LQ K+A R+L E +LQ +
Sbjct: 962 ASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQ 1021
Query: 333 --NMECLGMLHESQEEIKE 349
E L L +EE+ E
Sbjct: 1022 REQEELLARLEAEKEELSE 1040
Score = 42.7 bits (99), Expect = 0.002
Identities = 55/231 (23%), Positives = 102/231 (44%), Gaps = 24/231 (10%)
Query: 145 EQNESLEEQLGQAFDQVNQLQHELCKKD---ELLRIVSIASEESETDSSCSTPLRFNESF 201
+Q+ SL EQ+ +V L+ + + + + LR V +E E ++ +T + +
Sbjct: 1782 KQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEA-AALNTVQKLQDER 1840
Query: 202 SLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRET-- 259
L Q +L LQ L +LE E + A ++ + V ++ + ++ +T
Sbjct: 1841 RLLQE--RLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVR 1898
Query: 260 -NAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQ--HKLKEHVIEKEELKLHLQ--- 313
+A+ R+ L+G EL Q ++ L +Q+V L+ H + ++ ++ +L LQ
Sbjct: 1899 LSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEV 1958
Query: 314 ---ASKDAQRQLTMELHELQDRNMECLGMLHESQEEIK-----ELRSRSGP 356
S AQ + T+E E R + + L E +K ELR S P
Sbjct: 1959 ERLRSAQAQTERTLEARERAHR--QRVRGLEEQVSTLKGQLQQELRRSSAP 2007
Score = 36.6 bits (83), Expect = 0.11
Identities = 67/279 (24%), Positives = 122/279 (43%), Gaps = 34/279 (12%)
Query: 146 QNESLEEQLGQAFDQVNQLQ--HELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSL 203
+ +LEEQL + D+ + HE ++ E+ R+ S S S+ + L+ +
Sbjct: 562 ERRALEEQLQRLRDKTDGAMQAHEDAQR-EVQRLRSANELLSREKSNLAHSLQVAQ---- 616
Query: 204 SQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQM 263
Q +L +EKL+ +EE ++ + EE+++ V D + RE +
Sbjct: 617 -QQAEELRQEREKLQAAQEE----------LRRQRDRLEEEQEDAVQDGARVRRELE-RS 664
Query: 264 SRMTEELSGK----SDELIRYQEELSSLLSQIVDLQ---HKLKEHVIEKEELKLHLQASK 316
R E+L GK + EL+ +E LS Q LQ ++ E + + E ++ L+ S
Sbjct: 665 HRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELS- 723
Query: 317 DAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAA 376
+L E LQD ++ L L+ES + K +R A L + A G A
Sbjct: 724 --MTKLRAEEASLQD-SLSKLSALNESLAQDKLDLNRL--VAQL--EEEKSALQGRQRQA 776
Query: 377 EIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTR 415
E E T+ ++ E +Q+ ++ + ++R+A +
Sbjct: 777 EQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQ 815
Score = 32.3 bits (72), Expect = 2.1
Identities = 46/190 (24%), Positives = 82/190 (43%), Gaps = 18/190 (9%)
Query: 113 DMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKD 172
++VT L++ + + L A +LL L E+N+ L+++L + D + Q + E +D
Sbjct: 53 EIVTRNLSQPESPVLLPATEMASLLS----LQEENQLLQQELSRVEDLLAQSRAE---RD 105
Query: 173 ELLRIVSIASEESETDSSCST-PLRFNESFSLSQGLLQLE-MLQE-------KLKELEEE 223
EL + SE E L E L + ++L LQE KL+ +E
Sbjct: 106 ELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEG 165
Query: 224 NMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEE 283
++ + + Y+++ +L ++ E Q R TE LIR +EE
Sbjct: 166 QQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEE 225
Query: 284 --LSSLLSQI 291
S+ L+Q+
Sbjct: 226 QQRSASLAQV 235
Score = 31.6 bits (70), Expect = 3.5
Identities = 104/519 (20%), Positives = 198/519 (38%), Gaps = 95/519 (18%)
Query: 41 VELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTD 100
VEL L+E+ YR K+ Q+ + Q L L + +Y ++
Sbjct: 142 VELRRQLQEEQASYRRKL------------QAYQEGQQRQAQLVQRLQGKILQYKKRCSE 189
Query: 101 RVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQ 160
+Q+ + +++ E +DLE A + +R+ L++ N L EQL QA
Sbjct: 190 LEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAGSA 249
Query: 161 VNQLQHEL---------CKKDELLRIVSIASEESETDSSCSTP-----LRFNESFSLSQG 206
L ++ C+K+ R + EE ++ S L + + +
Sbjct: 250 NQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFRRL 309
Query: 207 LLQLEMLQEK------------LKELEEENMAL---------RSKACHIKTETVTYEEKE 245
+ +++M E+ + ++E + L R++A ++ + + + E
Sbjct: 310 VSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTGLRLAESRAEAA-LEKQALLQAQLE 368
Query: 246 QQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEK 305
+QL K LRE + +M +L + +LS+ ++++ +L++ +EK
Sbjct: 369 EQLRD---KVLREKDLAQQQMQSDLD---------KADLSARVTELGLAVKRLEKQNLEK 416
Query: 306 EELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQS 365
+ Q +KD LT +L L+ ++ L E + R A L S+S
Sbjct: 417 D------QVNKD----LTEKLEALESLRLQEQAALETEDGEGLQQTLRDLAQAVLSDSES 466
Query: 366 YGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSISFPALL 425
+G A+ + LS +R R ++ RGRS P
Sbjct: 467 GVQLSGSERTADASNGSLRGLS-------------GQRTPSPPRRSSPGRGRS---PRRG 510
Query: 426 PIPGSNRSSVIMTAKPFESGL--QQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLA 483
P P + SS T S L +Q + + + + +S+++ G+ +K S L
Sbjct: 511 PSPACSDSS---TLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALE 567
Query: 484 TALHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEGVS 522
L RL + + E+ QR++Q L E +S
Sbjct: 568 EQLQRLRDKTDGAMQAH----EDAQREVQRLRSANELLS 602
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 59.7 bits (143), Expect = 1e-08
Identities = 72/362 (19%), Positives = 152/362 (41%), Gaps = 39/362 (10%)
Query: 66 NQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRD 125
NQ+ + Q +L + E +++ L ++ ++ + N+++ + L RD
Sbjct: 844 NQEIVNLSKEAQKFDSSLGALKTELSYKTQEL-QEKTREVQERLNEMEQLKEQLENRDST 902
Query: 126 LELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEES 185
L+ R + + E+L Q ++V L E +L + I ++
Sbjct: 903 LQTVER--------------EKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQL 948
Query: 186 ETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTET-VTYEEK 244
++D + + + L L L+ QE + L+ + S+ H++ T T +E
Sbjct: 949 KSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEF 1008
Query: 245 EQQLVS-DCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVI 303
+Q++V D ++L N Q +T ++ K +E+I Q ++ SL+ + +LQ L+ +
Sbjct: 1009 QQKMVGIDKKQDLEAKNTQT--LTADV--KDNEIIEQQRKIFSLIQEKNELQQMLESVIA 1064
Query: 304 EKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFS 363
EKE+LK L+ + + + EL L D L + QE + + ++ H
Sbjct: 1065 EKEQLKTDLKENIEMTIENQEELRLLGDE-------LKKQQEIVAQEKN------HAIKK 1111
Query: 364 QSYGAFTGESLAAEIEGTMRKKLSLDEESSLF-----KQKAQQKRVFDTVRIANDTRGRS 418
+ + T + LA E K L E+ + QK++ + + N+ + +
Sbjct: 1112 EGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKE 1171
Query: 419 IS 420
++
Sbjct: 1172 LT 1173
Score = 56.6 bits (135), Expect = 1e-07
Identities = 58/259 (22%), Positives = 119/259 (45%), Gaps = 24/259 (9%)
Query: 100 DRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFD 159
+ ++ +TK +++ + L + L+ R A ++ + EQ+ +++E+ +
Sbjct: 1342 EEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTK 1401
Query: 160 QVNQLQHELCKKDELLRI----VSIASEESETDSSCSTPLRFNESFSLSQGLLQLE--ML 213
V++++ K LLRI + ++ E+ + + + Q +LQ E L
Sbjct: 1402 IVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQL 1461
Query: 214 QEKLKELEEENM----ALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEE 269
+E +KE+ +++ L+ C +K + T E L S+ E+ Q+ + ++
Sbjct: 1462 KENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNL-SEKETEISTIQKQLEAINDK 1520
Query: 270 LSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHEL 329
L K E+ Y++E + QI ++Q K V E ++ K H +A A + + ++ EL
Sbjct: 1521 LQNKIQEI--YEKEEQFNIKQISEVQEK----VNELKQFKEHRKAKDSALQSIESKMLEL 1574
Query: 330 QDRNMECLGMLHESQEEIK 348
+R L ESQEEI+
Sbjct: 1575 TNR-------LQESQEEIQ 1586
Score = 56.2 bits (134), Expect = 1e-07
Identities = 57/267 (21%), Positives = 123/267 (46%), Gaps = 27/267 (10%)
Query: 141 HVLSEQNESLEEQLGQAFDQVNQLQHELCK-KDELLRIVS-IASEESETDSSCSTPLRFN 198
H+++ + + L ++ +V L E+ K KD+L S S + E + + + F
Sbjct: 771 HIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFE 830
Query: 199 ESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRE 258
+ + + L + E + +++ L +E S +KTE ++Y+ +E Q + +E++E
Sbjct: 831 QKYKMV--LEENERMNQEIVNLSKEAQKFDSSLGALKTE-LSYKTQELQ---EKTREVQE 884
Query: 259 TNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDA 318
+M ++ E+L + L + E + + ++ ++K EK++LK LQ S
Sbjct: 885 RLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLK-QLQESLQI 943
Query: 319 QR-QLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAE 377
+R QL ++H+ + N++ L + E +K+ + T +L ++
Sbjct: 944 ERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQE-----------------TINTLKSK 986
Query: 378 IEGTMRKKLSLDEESSLFKQKAQQKRV 404
I + + L ++E + K + QQK V
Sbjct: 987 ISEEVSRNLHMEENTGETKDEFQQKMV 1013
Score = 53.5 bits (127), Expect = 9e-07
Identities = 61/290 (21%), Positives = 125/290 (43%), Gaps = 34/290 (11%)
Query: 134 QALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCST 193
+++ K L E L+ + Q + + ++ + + +E L++ +E E +
Sbjct: 1438 KSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETIN--- 1494
Query: 194 PLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCV 253
LR N LS+ ++ +Q K+LE N L++K I EKE+Q +
Sbjct: 1495 ELRVN----LSEKETEISTIQ---KQLEAINDKLQNKIQEIY-------EKEEQFNIKQI 1540
Query: 254 KELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQ 313
E++E ++ + E K L + ++ L +++ + Q +++ + EKEE+K
Sbjct: 1541 SEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMK---- 1596
Query: 314 ASKDAQRQLTMELHELQDRNMECLGMLHESQEE---------IKELRSRSGPTAHLYFSQ 364
Q L +E +L++ E + + ESQE+ + E + + HL
Sbjct: 1597 ---RVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQF 1653
Query: 365 SYGAFTGESLAAE-IEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIAND 413
E++ E I T +L+E S+ K++ + V +T+++ D
Sbjct: 1654 ETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERD 1703
Score = 49.7 bits (117), Expect = 1e-05
Identities = 71/362 (19%), Positives = 163/362 (45%), Gaps = 49/362 (13%)
Query: 15 EENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPH 74
EE L + E++ + + DL + E + ++ L +++ +D L ++ + +
Sbjct: 1695 EETLKVERDQLKENLRETITR-DLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISN 1753
Query: 75 QR---QHASDALSP----VLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLE 127
+ +H++DAL + E +M L ++ E + K + T L+ +DLE
Sbjct: 1754 MQKDLEHSNDALKAQDLKIQEELRIAHMHL-KEQQETIDKLRGIVSEKTDKLSNMQKDLE 1812
Query: 128 LAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCK--KDELLRI-------V 178
+ Q ++ Q +L++ + + +V++++ +L K KD+ L + +
Sbjct: 1813 NSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEME-QLKKQIKDQSLTLSKLEIENL 1871
Query: 179 SIASEESETDSSCSTPLRFNESFSLSQGLLQLE--MLQEKLKELEEENMALRSKACHIKT 236
++A + E + ++ ++ + L+LE L+E L+E + ++ ++ + +
Sbjct: 1872 NLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARM 1931
Query: 237 ETVTYEEKEQQL----------VSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSS 286
+ ++E +L +SD K+L ++ ++ + +EL K +L+R +E+
Sbjct: 1932 LSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKED--- 1988
Query: 287 LLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEE 346
V++ HK + E E+LK +A + + + M+ N + LHES EE
Sbjct: 1989 -----VNMSHK---KINEMEQLKKQFEAQNLSMQSVRMD-------NFQLTKKLHESLEE 2033
Query: 347 IK 348
I+
Sbjct: 2034 IR 2035
Score = 46.6 bits (109), Expect = 1e-04
Identities = 71/325 (21%), Positives = 136/325 (41%), Gaps = 42/325 (12%)
Query: 136 LLKRNHVLSEQNESLEEQLGQAFDQVN------QLQHE---LCKKDELLRIVSIASEESE 186
L + + E S+ E+ Q + + +LQ E L ++ ELL V SE E
Sbjct: 1244 LKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQE 1303
Query: 187 TDSSCSTPLRFNESFSLSQGLLQLEM----LQEKLKELEEENMALRSKACHIKTETVTYE 242
T + L + S L ++EM L EK +E +EE +L + ++KT E
Sbjct: 1304 TMNELEL-LTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALE 1362
Query: 243 EKEQQL---VSDCVKELRETNAQMSRMT----------------EELSGKSDELIRYQEE 283
K QL + + + +++E+ ++ + E+ K L+R + E
Sbjct: 1363 VKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIE 1422
Query: 284 LSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMEC---LGML 340
+ L ++ + ++K EK++L+ + + QL + E+ +++E L +
Sbjct: 1423 MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVA 1482
Query: 341 H----ESQEEIKELR-SRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLD-EESSL 394
H E +E I ELR + S + Q + L +I+ K+ + ++ S
Sbjct: 1483 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISE 1542
Query: 395 FKQKAQQKRVFDTVRIANDTRGRSI 419
++K + + F R A D+ +SI
Sbjct: 1543 VQEKVNELKQFKEHRKAKDSALQSI 1567
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/240 (23%), Positives = 109/240 (45%), Gaps = 33/240 (13%)
Query: 125 DLELAARIGQALLKRNHVLSEQNE--SLEEQLGQAFDQVNQLQHELCKKD----ELLRIV 178
++ L + + L + V E+++ S+EE L DQ+ + E +D E L+IV
Sbjct: 1667 NIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIV 1726
Query: 179 SIASEESETDSSCSTPLRFNESFSLSQGLL--QLEMLQEKLKELEEENMALRSKACHIKT 236
+ +E + E+ +G++ + + K+LE N AL+++ I+
Sbjct: 1727 HMHLKEHQ------------ETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQE 1774
Query: 237 ET--VTYEEKEQQLVSDCVKEL-RETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVD 293
E KEQQ D ++ + E ++S M ++L + +L +EL + Q++
Sbjct: 1775 ELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLIT 1834
Query: 294 LQHKLKE---HVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKEL 350
L+ + E V E E+LK + + ++ L +L+ N+ LHE+ EE+K +
Sbjct: 1835 LKKDVNETQKKVSEMEQLKKQI-------KDQSLTLSKLEIENLNLAQKLHENLEEMKSV 1887
Score = 43.5 bits (101), Expect = 9e-04
Identities = 68/347 (19%), Positives = 149/347 (42%), Gaps = 32/347 (9%)
Query: 18 LMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQ 77
+ S ++ + + NE ++ + L+EQ +L ++ + EN TQ H+
Sbjct: 1620 MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIET-ENIRLTQILHENL 1678
Query: 78 HASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALL 137
+ + V E + T +VE+ N + +T RDLE Q L
Sbjct: 1679 ---EEMRSVTKERDDLRSVEETLKVERDQLKENLRETIT-------RDLEK-----QEEL 1723
Query: 138 KRNHV-LSEQNESLEEQLGQAFDQVNQL---QHELCKKDELLRIVSIASEESETDSSCST 193
K H+ L E E++++ G ++ N++ Q +L ++ L+ + +E +
Sbjct: 1724 KIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHL 1783
Query: 194 PLRFNESFSLSQGLL--QLEMLQEKLKELEEENMALRSKACHIKT---------ETVTYE 242
+ E+ +G++ + + L K+LE N L+ K +K + V
Sbjct: 1784 KEQ-QETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNET 1842
Query: 243 EKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHV 302
+K+ + K++++ + +S++ E + +L EE+ S++ + +L+ +
Sbjct: 1843 QKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLK 1902
Query: 303 IEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKE 349
+E+++LK LQ +K ++ EL + + E + + +E+I E
Sbjct: 1903 LERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISE 1949
Score = 43.1 bits (100), Expect = 0.001
Identities = 64/322 (19%), Positives = 136/322 (42%), Gaps = 29/322 (9%)
Query: 49 EQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQM--- 105
E L Q++ ++TL +++ +++ H ++ + ++ F+ ++G D+ + +
Sbjct: 971 ESLKQHQETINTLKSKISEEVSRNLHMEENTGET------KDEFQQKMVGIDKKQDLEAK 1024
Query: 106 -TKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQL 164
T+T D+ + + E+ R + + L + + + E L+ L + + +
Sbjct: 1025 NTQTLT-ADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIEN 1083
Query: 165 QHEL-CKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEE 223
Q EL DEL + I ++E + LS+ +L ++EKLKE ++
Sbjct: 1084 QEELRLLGDELKKQQEIVAQEKNH--------AIKKEGELSRTCDRLAEVEEKLKEKSQQ 1135
Query: 224 NMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEE 283
+ + +++ E ++K + + + EL+ + M E + +L EE
Sbjct: 1136 LQEKQQQLLNVQEEMSEMQKKINE-IENLKNELKNKELTLEHMETERLELAQKLNENYEE 1194
Query: 284 LSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHES 343
+ S+ + L+ K E++ L+ +++ + Q EL L E
Sbjct: 1195 VKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIH-------LKEH 1247
Query: 344 QEEIKEL-RSRSGPTAHLYFSQ 364
QE I EL RS S TA + +Q
Sbjct: 1248 QETIDELRRSVSEKTAQIINTQ 1269
Score = 42.0 bits (97), Expect = 0.003
Identities = 75/372 (20%), Positives = 149/372 (40%), Gaps = 56/372 (15%)
Query: 65 ENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERD- 123
E Q+ T+ +R + + L L + ++ K ++ V L E+D
Sbjct: 874 ELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDD 933
Query: 124 -RDLELAARIGQALLKRN-HVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIA 181
+ L+ + +I + LK + H N +EQL A + + Q Q +I
Sbjct: 934 LKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQE------------TIN 981
Query: 182 SEESETDSSCSTPLRFNESFSLSQGLLQLEMLQ-EKLKELEEENMALRSKACHIKTETVT 240
+ +S+ S L E+ ++ Q +M+ +K ++LE +N ++ +K +
Sbjct: 982 TLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNT--QTLTADVKDNEII 1039
Query: 241 YEEKE-----------QQLVSDCVKE-------LRETNAQMSRMTEELSGKSDELIRYQE 282
++++ QQ++ + E L+E EEL DEL + QE
Sbjct: 1040 EQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQE 1099
Query: 283 ELSSLLSQIVDLQHKLKEHVIEKE-ELKLHLQASKDAQRQLTMELHELQDRNMECLGMLH 341
++ + K H I+KE EL + + +L + +LQ++ + L +
Sbjct: 1100 IVA-----------QEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNV-- 1146
Query: 342 ESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAE-IEGTMRKKLSLDEESSLFKQKAQ 400
QEE+ E++ + +L T E + E +E + + +E S+ K++
Sbjct: 1147 --QEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKV 1204
Query: 401 QKRV---FDTVR 409
K + F+T R
Sbjct: 1205 LKELQKSFETER 1216
Score = 42.0 bits (97), Expect = 0.003
Identities = 87/444 (19%), Positives = 197/444 (44%), Gaps = 55/444 (12%)
Query: 6 NAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYE 65
N + + + +E +++ + E+I D N+ + + E+ Q+ +K + +
Sbjct: 1494 NELRVNLSEKETEISTIQKQLEAINDKLQNK-------IQEIYEKEEQFNIKQISEVQEK 1546
Query: 66 NQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRD 125
+ Q R+ AL + ++ M+ T+R+++ + +I ++ E R
Sbjct: 1547 VNELKQFKEHRKAKDSALQSIESK-----MLELTNRLQE---SQEEIQIMIKEKEEMKRV 1598
Query: 126 LELAARIGQALLKRN--HVLSEQNESLEEQLG-QAFDQVNQLQHELCKKDEL---LRIVS 179
E A +I + LK N ++++ ES E++ VN+ Q ++C+ + L
Sbjct: 1599 QE-ALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQK 1657
Query: 180 IASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKT--- 236
+ E ET++ T + L + L ++ + ++ +L L+ + +K
Sbjct: 1658 LNLENIETENIRLTQI-------LHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLR 1710
Query: 237 ETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELS----SLLSQIV 292
ET+T + ++Q+ + L+E + ++ +S K++E+ Q++L +L +Q +
Sbjct: 1711 ETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDL 1770
Query: 293 DLQHKLK---EHVIEKEEL--KLHLQASK------DAQRQLTMELHELQDRNMECLGMLH 341
+Q +L+ H+ E++E KL S+ + Q+ L +LQ++ E H
Sbjct: 1771 KIQEELRIAHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEH 1830
Query: 342 ES---QEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEG-TMRKKL--SLDEESSLF 395
+ ++++ E + + L + T L EIE + +KL +L+E S+
Sbjct: 1831 QLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKL--EIENLNLAQKLHENLEEMKSVM 1888
Query: 396 KQKAQQKRVFDTVRIANDTRGRSI 419
K++ +RV +T+++ D S+
Sbjct: 1889 KERDNLRRVEETLKLERDQLKESL 1912
Score = 40.0 bits (92), Expect = 0.010
Identities = 51/228 (22%), Positives = 95/228 (41%), Gaps = 24/228 (10%)
Query: 145 EQNESLEEQLGQAFDQVNQLQHELCKKDELL---------RIVSIASEESETDSSCSTPL 195
E + LEE L FD + +L++ + K+++ + RI++I +E +E + +T
Sbjct: 2267 EMTQFLEEWLNTRFD-IEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATIS 2325
Query: 196 RFNESFSLSQGLLQLEMLQEKLKELEEENMALR-SKACHIKTETVTYEEKEQQLVSDCVK 254
+ E L+ L+EK ++L + L+ S A + T + K + S +
Sbjct: 2326 KEWEQ--------DLKSLKEKNEKLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQ 2377
Query: 255 ----ELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKL 310
++RE + E K ++I+ Q+EL I LQ K+ E E+ K
Sbjct: 2378 LTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKE 2437
Query: 311 HLQASKD-AQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPT 357
+Q +D E++D M+ + + E + KE T
Sbjct: 2438 TIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISAT 2485
Score = 37.4 bits (85), Expect = 0.064
Identities = 50/265 (18%), Positives = 112/265 (42%), Gaps = 19/265 (7%)
Query: 143 LSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFS 202
L +N L+E++ + Q+++++ +L + A ++ + D FNE
Sbjct: 644 LRSENLELKEKMKELATTYKQMENDI----QLYQSQLEAKKKMQVDLEKELQSAFNEITK 699
Query: 203 LSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCV--KELRETN 260
L+ ++ K+ + N+ L K ++ E E+ + L + + EL+
Sbjct: 700 LTS------LIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLP 753
Query: 261 AQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQR 320
+++ R+ +E+ KS+EL E L S++V + +++ + E + K L ++ +
Sbjct: 754 SEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYK 813
Query: 321 QLTMELHELQDRNME----CLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAA 376
E + +M+ +L E++ +E+ + S F S GA E L+
Sbjct: 814 STDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQK--FDSSLGALKTE-LSY 870
Query: 377 EIEGTMRKKLSLDEESSLFKQKAQQ 401
+ + K + E + +Q +Q
Sbjct: 871 KTQELQEKTREVQERLNEMEQLKEQ 895
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 59.3 bits (142), Expect = 2e-08
Identities = 64/260 (24%), Positives = 114/260 (43%), Gaps = 18/260 (6%)
Query: 146 QNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLS- 204
+N LE+ + QV++L+ EL K+ E EE ++ L+ + L+
Sbjct: 924 RNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTG 983
Query: 205 ---QGLLQLEMLQEKLKELEEENMALR----SKACHIKT------ETVTYEEKEQQLVSD 251
Q ++++ +E+L ++E+E M L+ +KA H+ +T T EK+ V +
Sbjct: 984 TARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKE 1043
Query: 252 CVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLH 311
K T +++ ++ EL EL S L Q+ +L+ L++ + EE
Sbjct: 1044 LEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEE---K 1100
Query: 312 LQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTG 371
KD +L E++D+ E L M +E EL+ R+ HL +
Sbjct: 1101 YTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEM 1160
Query: 372 ESLAAEIEGTMRK-KLSLDE 390
E ++EGT+ K +L L E
Sbjct: 1161 EQKIIKLEGTLEKSELELKE 1180
Score = 51.6 bits (122), Expect = 3e-06
Identities = 73/332 (21%), Positives = 145/332 (43%), Gaps = 56/332 (16%)
Query: 100 DRVEQMTKTYNDIDMVTHLLAERDR-DLELAARIGQALLKRNHVLSEQNESLEEQLGQAF 158
D + TKT +++ T+ + E ++ + +AL KR E LE +L A
Sbjct: 1024 DMILDQTKT--ELEKKTNAVKELEKLQHSTETELTEALQKR--------EVLETELQNAH 1073
Query: 159 DQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLK 218
++ +L + ++L+ ++ EE T T L + +++E +++L
Sbjct: 1074 GELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTA-------ELRECKMEIEDKKQELL 1126
Query: 219 E----LEEENMALRSKACHIKTETVTYEEKEQQLVSDCVK----------ELRETNAQMS 264
E L+E N L+ +A + +T E ++ +K EL+E N Q+
Sbjct: 1127 EMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIE 1186
Query: 265 RMTEELSGKSDEL-------IRYQEELSSLLSQIVDLQHKLK--EHVIEKEELKLHLQAS 315
+ ++L ++L ++ ++E+S L +I Q ++K E V++++E + Q
Sbjct: 1187 SLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYK 1246
Query: 316 K--DAQRQLTMELHELQDRNMECLGMLH---ESQEEIKELRSRSGPTAHLYFSQ-SYGAF 369
+ D ++L + ++Q+ + E H ++Q EI+ L S L + ++G
Sbjct: 1247 EAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNH 1306
Query: 370 TGESLA------AEIEGTMR---KKLSLDEES 392
E L A +E M+ KKLS + ES
Sbjct: 1307 LAEELGASKVREAHLEARMQAEIKKLSAEVES 1338
Score = 44.7 bits (104), Expect = 4e-04
Identities = 57/268 (21%), Positives = 112/268 (41%), Gaps = 28/268 (10%)
Query: 131 RIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSS 190
+I A K + EQ++ +E+Q + +L+ +L KKD+ + E+ +T S
Sbjct: 747 KICLAFEKAKKIHLEQHKEMEKQ-------IERLEAQLEKKDQQFK------EQEKTMSM 793
Query: 191 CSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLV- 249
+ + S L E E KE +++ AL++ + ET+ + + L
Sbjct: 794 LQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEI 853
Query: 250 --SDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEE 307
+ V L + + ++L KS+E+ Q+EL H L+E +
Sbjct: 854 CKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIK-------NHSLQETSEQNVI 906
Query: 308 LKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLY----FS 363
L+ LQ + +Q T+ EL+D + + + ++E+++ R S S
Sbjct: 907 LQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCES 966
Query: 364 QSYGAFTGESLAAEIEGTMRK-KLSLDE 390
++ A E+ GT R+ K+ +D+
Sbjct: 967 AAHEADLKRQKVIELTGTARQVKIEMDQ 994
Score = 38.5 bits (88), Expect = 0.029
Identities = 63/298 (21%), Positives = 127/298 (42%), Gaps = 35/298 (11%)
Query: 75 QRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLE------- 127
Q+Q AS P+L E+ + + + + + N ++ ++ E+++ L+
Sbjct: 280 QQQAAS---VPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECI 336
Query: 128 -LAARIGQALLKRNHVLSEQNESL--EEQLGQAFDQVNQLQHELCKKDELLRIVSIASEE 184
L + + + ++NE+L E+L +AF Q KK ++ + +EE
Sbjct: 337 KLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQY--------KKKVAEKLEKVQAEE 388
Query: 185 SETDSSCSTPLRFNESFSLSQGLL--QLEMLQEKLKELEEENMALRSKACHI---KTETV 239
+ + + + N+ GL +LE+L+EKL++L+EEN + K + +E +
Sbjct: 389 EILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVM 448
Query: 240 TYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDEL---IRYQEELSSLLSQIVD--- 293
+ +Q + EL E ++ R L ++ EL + Q E L Q ++
Sbjct: 449 AQLTESRQSILKLESEL-ENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSR 507
Query: 294 LQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELR 351
++ + E +I + LK L K + M ++ C+G ++ I ELR
Sbjct: 508 VELRSLEKIISQLPLKRELFGFKSYLSKYQMS--SFSNKEDRCIGCCEANKLVISELR 563
Score = 35.4 bits (80), Expect = 0.24
Identities = 47/221 (21%), Positives = 96/221 (43%), Gaps = 9/221 (4%)
Query: 136 LLKRNHVLSEQNESLEEQLGQAFDQVNQLQ--HELCKKDELL--RIVSIASEESETDSSC 191
L+ +NH L + ES+ +L Q+ +V+ L+ + +L +I+++ +E S D
Sbjct: 248 LVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQIINLEAEVSAQDK-- 305
Query: 192 STPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSD 251
LR E+ L Q + ++ L+E +EE + L+ + E + + + +
Sbjct: 306 --VLREAEN-KLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYN 362
Query: 252 CVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLH 311
+ + ++ E+L E + L++ + LQ + + E E LK
Sbjct: 363 AEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEK 422
Query: 312 LQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRS 352
L+ K+ +L + +N E + L ES++ I +L S
Sbjct: 423 LRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLES 463
Score = 33.9 bits (76), Expect = 0.71
Identities = 26/115 (22%), Positives = 55/115 (47%), Gaps = 11/115 (9%)
Query: 218 KELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDEL 277
K+ E+E L + ++T+ + E + SD + +Q + EEL K+
Sbjct: 630 KQYEKERQRLVTGIEELRTKLIQIEAEN----SDLKVNMAHRTSQFQLIQEELLEKASNS 685
Query: 278 IRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDR 332
+ + E++ SQ++ L+ +L+E ++ + A+K+A +L EL E ++
Sbjct: 686 SKLESEMTKKCSQLLTLEKQLEEKIVAYSSI-----AAKNA--ELEQELMEKNEK 733
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 58.9 bits (141), Expect = 2e-08
Identities = 100/429 (23%), Positives = 172/429 (40%), Gaps = 70/429 (16%)
Query: 132 IGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSC 191
+ LL+RN EQ LE +L +QV LQ K E L I E DSS
Sbjct: 56 LSSQLLRRN----EQIRKLEARLSDYAEQVRNLQ----KIKEKLEIAL----EKHQDSSM 103
Query: 192 STPLRFNESFS-----LSQGLLQL-----EMLQEKLKELEEENMALRSKACHIKTETVTY 241
NE+F +++GL + EK+ +LE+E L ++ +K +++
Sbjct: 104 RKFQEQNETFQANRAKMAEGLALALARKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNL 163
Query: 242 EEK----------EQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQI 291
++ +QQ +S L + + +M +EL ++ EL R QEEL +
Sbjct: 164 FQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMS 223
Query: 292 VDLQHKLKE---HVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLH-ESQEEI 347
DL KL+E H EE + H+ ASK L + + + L + Q+
Sbjct: 224 SDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKVT 283
Query: 348 KELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEE-SSLFKQKAQQKRVFD 406
E + + HL + A +E + + LS +E L K+K ++ +
Sbjct: 284 AETQEKEDVITHL-----------QEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLE 332
Query: 407 TVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAG 466
DTR + ++ S+++ I T + L+QT +SEE
Sbjct: 333 ------DTRQQLLA-------ARSSQAKAINTLETRVRELEQTL--------QASEEQLQ 371
Query: 467 SSQKMGQPGPSGDSDLATALHRLSLRRQNYLSEKQFFAEEWQR-KIQVLADQKEGVSGCV 525
S+ + + +LA A S +Q L+ +Q F E Q + Q++A ++ +
Sbjct: 372 QSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLERTQALEAQIVALERTRAADQT 431
Query: 526 TPTESLASL 534
T + + L
Sbjct: 432 TAEQGMRQL 440
Score = 53.9 bits (128), Expect = 7e-07
Identities = 82/386 (21%), Positives = 162/386 (41%), Gaps = 86/386 (22%)
Query: 25 DSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTL---------FLYENQDWTQSPHQ 75
D S + S++ L E + LE +L Y +V L L ++QD + Q
Sbjct: 48 DGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQ 107
Query: 76 RQHAS---------DALSPVLAEETFRYMILGTDRVEQMTKTYNDI--------DMVTHL 118
Q+ + + L+ LA + + +++++Q+ K N + + +L
Sbjct: 108 EQNETFQANRAKMAEGLALALARKDQEW----SEKMDQLEKEKNILTAQLQEMKNQSMNL 163
Query: 119 LAERDRDLELAARIGQALLKRNHVLSEQNESL---EEQLGQAFDQVNQLQHELCKKDELL 175
RD EL Q L K H+L ++ ESL E++L ++++ Q EL +++
Sbjct: 164 FQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQM- 222
Query: 176 RIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIK 235
S LSQ +LE LQ LEE+ + + +
Sbjct: 223 ------------------------SSDLSQ---KLEELQRHYSTLEEQRDHVIASKTGAE 255
Query: 236 TETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSL-------L 288
++ E+KEQ+L + +++ + + ++T E K D + QE+++SL L
Sbjct: 256 SKITALEQKEQELQA----LIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNL 311
Query: 289 SQIVDLQHKLKEHVIEK---EELKLHLQASKDAQ-----------RQLTMELHELQDRNM 334
S +Q LKE + + E+ + L A++ +Q R+L L +++
Sbjct: 312 SGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQLQ 371
Query: 335 ECLGMLHESQEEIKELRSRSGPTAHL 360
+ G++ + +I+EL + + ++H+
Sbjct: 372 QSKGIVAAQETQIQELAAANQESSHV 397
Score = 44.7 bits (104), Expect = 4e-04
Identities = 77/384 (20%), Positives = 159/384 (41%), Gaps = 64/384 (16%)
Query: 15 EENLMNSNHRDSESITDVCSNEDLPEVEL-VSLLEEQ-----------------LPQYRL 56
+E LMNSN S+ ++ L E++ S LEEQ L Q
Sbjct: 213 QEELMNSNQMSSDL------SQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQ 266
Query: 57 KVDTLFLYENQDWTQSPHQRQHASDALSPVLA-----EETFRYMILGTDRVEQMTKTYND 111
++ L + D + + Q D ++ + E+ + G + V+++ K
Sbjct: 267 ELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLSGEEHVQELLKEKT- 325
Query: 112 IDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKK 171
+ E R LAAR QA K + L + LE+ L + +Q+ Q + + +
Sbjct: 326 ---LAEQNLEDTRQQLLAARSSQA--KAINTLETRVRELEQTLQASEEQLQQSKGIVAAQ 380
Query: 172 DELLRIVSIASEESETDSSCSTPLR---FNESFSLSQGLLQLEML--------QEKLKEL 220
+ ++ ++ A++ES + L + +L ++ LE ++ +++L
Sbjct: 381 ETQIQELAAANQESSHVQQQALALEQQFLERTQALEAQIVALERTRAADQTTAEQGMRQL 440
Query: 221 EEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRY 280
E+EN AL K C + E + + +K+L+E +Q ++ ++ +E+ +
Sbjct: 441 EQENAAL--KECRNEYERSLQNHQFE------LKKLKEEWSQREIVSVAMAQALEEVRKQ 492
Query: 281 QEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGML 340
+EE + + + + ++++ EK E+ L Q E+ +L+ + L +
Sbjct: 493 REEFQQQAANLTAIIDEKEQNLREKTEVLL----------QKEQEILQLERGHNSALLQI 542
Query: 341 HESQEEIKELRSRSGPTAHLYFSQ 364
H+ Q E++ LR+ A + Q
Sbjct: 543 HQLQAELEALRTLKAEEAAVVAEQ 566
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 58.9 bits (141), Expect = 2e-08
Identities = 89/414 (21%), Positives = 170/414 (41%), Gaps = 55/414 (13%)
Query: 26 SESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSP 85
SE ++ S + + E +L+EE L + D L E Q+ +R+ AL
Sbjct: 708 SEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQE--DLLRKRERELTALKG 765
Query: 86 VLAEETFRYMILGTDRVEQMTKTYN-DIDMVTHLLAERDRDLE-LAARIGQA-------- 135
L EE + ++++ + Y+ ++ + + E +++E LA+R +
Sbjct: 766 ALKEEVSSH----DQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTE 821
Query: 136 -----LLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLR------------IV 178
L + N L ++E LE ++ Q Q+ L+ + K E L+ +V
Sbjct: 822 MRVKLLQEENEKLQGRSEELERRVAQLQRQIEDLKGDEAKAKETLKKYEGEIRQLEEALV 881
Query: 179 SIASEESETDSSCSTPLRFNESF--SLSQGLLQLEMLQEKLKELEEENMALRSKACHIKT 236
EE E S+ E+ +LSQ + + L EKLKE E+ LR ++
Sbjct: 882 HARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEMEN 941
Query: 237 ETVTYE---EKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVD 293
E EK Q+ ++D V+ R + ++ +E K+ ++ +
Sbjct: 942 ERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEKNRR-------------ELAE 988
Query: 294 LQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSR 353
+Q +LKE +E E+ +L +D R + EL + Q E L ++ +K+L
Sbjct: 989 MQRQLKEKTLEAEKSRLTAMKMQDEMRLMEEELRDYQRAQDEALTKRQLLEQTLKDLEYE 1048
Query: 354 SGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLS----LDEESSLFKQKAQQKR 403
+HL +S E +++E + ++ + L E S +++ +Q R
Sbjct: 1049 LEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLLSERISRSREQMEQLR 1102
Score = 42.0 bits (97), Expect = 0.003
Identities = 56/266 (21%), Positives = 106/266 (39%), Gaps = 41/266 (15%)
Query: 100 DRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFD 159
D +EQ +K +T +AE R L+L + Q + + + E L Q + +
Sbjct: 611 DLLEQKSK-------LTIEVAELQRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVE 663
Query: 160 QVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKE 219
+ + LQ L EESE + + F Q ++ LQ++L E
Sbjct: 664 ENSTLQQRL--------------EESEGELRKNLEELFQVKMEREQHQTEIRDLQDQLSE 709
Query: 220 LEEE-NMALRS-------------KACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSR 265
+ +E + A RS +A + + +E+++ L+ K RE A
Sbjct: 710 MHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLR---KRERELTALKGA 766
Query: 266 MTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTME 325
+ EE+S E+ + +E+ +++ L+ ++E E L S+ Q M
Sbjct: 767 LKEEVSSHDQEMDKLKEQYD---AELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMR 823
Query: 326 LHELQDRNMECLGMLHESQEEIKELR 351
+ LQ+ N + G E + + +L+
Sbjct: 824 VKLLQEENEKLQGRSEELERRVAQLQ 849
Score = 42.0 bits (97), Expect = 0.003
Identities = 58/247 (23%), Positives = 106/247 (42%), Gaps = 20/247 (8%)
Query: 118 LLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKK--DELL 175
L+ E RD + A +AL KR +L + + LE +L +A + + L K+ D++
Sbjct: 1016 LMEEELRDYQRAQ--DEALTKRQ-LLEQTLKDLEYEL-EAKSHLKDDRSRLVKQMEDKVS 1071
Query: 176 RI-VSIASEESETDSSCSTPLRFNESFS-LSQGLLQLEMLQEKLK----ELEEENMALRS 229
++ + + E + +D R E L LLQ ++ L+ LE +N L+S
Sbjct: 1072 QLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQNKDLKS 1131
Query: 230 KACHI-------KTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELI-RYQ 281
+ H+ K V E + D ++ A + L K EL+ +
Sbjct: 1132 RIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD 1191
Query: 282 EELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLH 341
+E SL Q L +LK + EE + + + ++++L EL E D N G L+
Sbjct: 1192 DEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLN 1251
Query: 342 ESQEEIK 348
+++++
Sbjct: 1252 SMKKDLR 1258
Score = 34.7 bits (78), Expect = 0.42
Identities = 75/352 (21%), Positives = 136/352 (38%), Gaps = 75/352 (21%)
Query: 205 QGLLQLEML-QEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQM 263
Q LQLE+ Q+ +KE E A + E V QQ + + ELR+ ++
Sbjct: 627 QRQLQLEVKNQQNIKEERERMRANLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEEL 686
Query: 264 SRMTEELSGKSDELIRYQEELSS------------------LLSQIVDLQHKLKEHVIEK 305
++ E E+ Q++LS L+ +++ + L++ +I K
Sbjct: 687 FQVKMEREQHQTEIRDLQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAK 746
Query: 306 EE--------------LKLHLQASKDAQRQLTMELHELQDRNMECL-GMLHESQEEIKEL 350
EE LK L+ + Q +L E D ++ L + E+ + ++ L
Sbjct: 747 EEQEDLLRKRERELTALKGALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVL 806
Query: 351 RSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSL-FKQKAQQKRVFDTVR 409
SRS T E A E MR KL +E L + + ++RV R
Sbjct: 807 ASRSN--------------TSEQDQAGTE--MRVKLLQEENEKLQGRSEELERRVAQLQR 850
Query: 410 IANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQ 469
D +G + + T K +E ++Q E+ +L++ +E + +
Sbjct: 851 QIEDLKG--------------DEAKAKETLKKYEGEIRQLEE-ALVHARKEEKEAVSARR 895
Query: 470 KMGQPGPSGDSDLATALHRLS--LRRQNYLSEKQFFAEEWQRKIQVLADQKE 519
+ +++L A LS + Q LSEK E + +++ L ++ E
Sbjct: 896 AL-------ENELEAAQGNLSQTTQEQKQLSEKLKEESEQKEQLRRLKNEME 940
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 57.8 bits (138), Expect = 5e-08
Identities = 67/276 (24%), Positives = 126/276 (45%), Gaps = 29/276 (10%)
Query: 142 VLSEQNESLEEQLGQAFDQVNQLQH-ELCKKDEL---LRIVSIASEESETDSS---CSTP 194
+L+ + E+L+EQL + ++ +++ + +K +L LR E+ E D T
Sbjct: 311 LLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETK 370
Query: 195 LRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVK 254
+ +E+ + + ++ L+ ++K++ + LR + K+E +EE E+ L +
Sbjct: 371 RQMHETLEMKEE--EIAQLRSRIKQMTTQGEELREQK--EKSERAAFEELEKALSTAQKT 426
Query: 255 E--LRETNAQMSRMTEELSGKSDE-LIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLH 311
E R+ A+M + + S+E I Q+ELS + ++VD+ K E I K + KLH
Sbjct: 427 EEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQ-KLH 485
Query: 312 LQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTG 371
+ +++LT +L + E QE++K +S Y S
Sbjct: 486 EKELARKEQELTKKLQTRE----------REFQEQMKVALEKSQSE---YLKISQEKEQQ 532
Query: 372 ESLAAEIEGTMRKKLSLDEESSLFKQKAQQKRVFDT 407
ESLA E E ++KK L E + + Q+ + T
Sbjct: 533 ESLALE-ELELQKKAILTESENKLRDLQQEAETYRT 567
Score = 50.1 bits (118), Expect = 1e-05
Identities = 68/325 (20%), Positives = 134/325 (41%), Gaps = 36/325 (11%)
Query: 103 EQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESL----EEQLGQAF 158
E+ K+ D + L+E ELA ++ K +L + L +
Sbjct: 1193 EKSNKSLEDKSLEFKKLSE-----ELAIQLDICCKKTEALLEAKTNELINISSSKTNAIL 1247
Query: 159 DQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLK 218
+++ QH K E L I + E E T + + S Q QLE + ++K
Sbjct: 1248 SRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIK 1307
Query: 219 ELEEENMALRSKACHIKTETVTYEE---KEQQLVSDCVKELRETNAQMSRMTEELSGKSD 275
++ + +L ++ ++ E ++ +++ ++ KEL E ++ M EEL K
Sbjct: 1308 SMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEK-- 1365
Query: 276 ELIRYQEELSSLLSQIVDLQHKLKEHV--IEKEELKLHLQASKDAQR--------QLTME 325
+ E+SSL Q+ DL +L+ + EKE L+ D ++ L+ +
Sbjct: 1366 -----KVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFK 1420
Query: 326 LHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKK 385
+ L + L + + + E + + A F+Q T + L ++E ++
Sbjct: 1421 VDTLSKEKISALEQVDDWSNKFSEWKKK----AQSRFTQHQN--TVKELQIQLELKSKEA 1474
Query: 386 LSLDEESSLFKQKA-QQKRVFDTVR 409
DE+ +L K++ QQ + FD ++
Sbjct: 1475 YEKDEQINLLKEELDQQNKRFDCLK 1499
Score = 49.3 bits (116), Expect = 2e-05
Identities = 70/346 (20%), Positives = 146/346 (42%), Gaps = 71/346 (20%)
Query: 89 EETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDL---------ELAARIGQALLKR 139
E+T + + +E ++ +++ H L E L EL A++ + ++
Sbjct: 673 EKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDE---QK 729
Query: 140 NH-------VLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETD---- 188
NH ++ E S++ DQ+NQL+ L ++D+ L+ E E D
Sbjct: 730 NHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRS 789
Query: 189 ----SSCSTPLRFNESFSLSQGLL------QLEMLQEKLKELEEENMALRSKACHI---K 235
S L +S+ + QL LQ+KL +LE E + L + + K
Sbjct: 790 EGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQK 849
Query: 236 TETVTYEEKEQQLVSDCVKELRETNAQMSR----MTEELSGKSDELIRYQEELSSLLSQI 291
+ T + + V D +++L + N++M + +T+ K ++ + QE+ +L +
Sbjct: 850 KDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEK 909
Query: 292 VDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELR 351
++ +++E ++ E+ ++K+ + E +E + +N E + E++K+
Sbjct: 910 ENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQE------KKMEKVKQ-- 961
Query: 352 SRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQ 397
A E++ T++KKL LD+E+ L K+
Sbjct: 962 ----------------------KAKEMQETLKKKL-LDQEAKLKKE 984
Score = 47.4 bits (111), Expect = 6e-05
Identities = 72/372 (19%), Positives = 159/372 (42%), Gaps = 21/372 (5%)
Query: 48 EEQLPQYRLKVDTLFLYENQDWTQSPHQRQHA-SDALSPVLAEETFRYMILGTDRVEQMT 106
EEQ+ + + + + Q+ T+ R+ + + L + Y+ + ++ +Q +
Sbjct: 475 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQES 534
Query: 107 KTYNDIDMVTH-LLAERD---RDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVN 162
++++ +L E + RDL+ A + + + S +SL+E Q+ D
Sbjct: 535 LALEELELQKKAILTESENKLRDLQQEAETYRTRILE--LESSLEKSLQENKNQSKDLAV 592
Query: 163 QLQHELCKKDELLRIV------SIASEESETDSSCSTPLR-FNESFSLSQGLLQLEMLQE 215
L+ E K ++ + ++ + S + + D+ + L+ + + L+ + QE
Sbjct: 593 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQE 652
Query: 216 KLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSD 275
K L+++ + ++ + +T+ + +Q + EL E ++ EELS D
Sbjct: 653 KETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 712
Query: 276 ELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHL--QASKDAQRQLTMELHELQDRN 333
+ + ++EL + + + + + + +I++ E+ + +A KD QL + L E
Sbjct: 713 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHL 772
Query: 334 MECLGMLHESQEEIKELRSR-SGPTAHLYFSQSYGAFTGESLAA---EIEGTMRKKLSLD 389
E + + +IK +A L QSY + T E A ++ +K L L+
Sbjct: 773 KEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLE 832
Query: 390 EESSLF-KQKAQ 400
E L KQ A+
Sbjct: 833 TERILLTKQVAE 844
Score = 46.2 bits (108), Expect = 1e-04
Identities = 72/373 (19%), Positives = 149/373 (39%), Gaps = 40/373 (10%)
Query: 42 ELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDR 101
E + + EE++ Q R ++ + + Q + A + L L+ T+
Sbjct: 375 ETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ------KTEE 428
Query: 102 VEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQV 161
+ K D + T + + L + + + V+ +S EEQ+ + +
Sbjct: 429 ARRKLKAEMDEQIKTIEKTSEEERISLQQELSRV---KQEVVDVMKKSSEEQIAK----L 481
Query: 162 NQL-QHELCKKD-ELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKE 219
+L + EL +K+ EL + + E + + +E +SQ Q E L L+E
Sbjct: 482 QKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLA--LEE 539
Query: 220 LEEENMAL----RSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSD 275
LE + A+ +K ++ E TY + +L S K L+E Q + L + +
Sbjct: 540 LELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKN 599
Query: 276 ELIRYQEELSSLL----SQIVDLQHKLKEHVIEK-EELKLHLQASKDAQRQLTMELHELQ 330
++ +E++ ++ +++ L+H+ EK + LK Q + R+ + E
Sbjct: 600 ---KHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETL 656
Query: 331 DRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDE 390
++ E + H + K L L ESL++E+ ++ + L+E
Sbjct: 657 LKDKEIIFQAHIEEMNEKTLEKLDVKQTEL-----------ESLSSELSEVLKARHKLEE 705
Query: 391 ESSLFKQKAQQKR 403
E S+ K + + +
Sbjct: 706 ELSVLKDQTDKMK 718
Score = 43.9 bits (102), Expect = 7e-04
Identities = 52/197 (26%), Positives = 92/197 (46%), Gaps = 21/197 (10%)
Query: 211 EMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVK-ELRETNAQMSRMTEE 269
E ++KE EE+ + L ++ +K E T ++KE + V+ VK + E A R+ E
Sbjct: 1574 EEKDNRVKEAEEKILTLENQVYSMKAELET-KKKELEHVNLSVKSKEEELKALEDRLESE 1632
Query: 270 LSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHEL 329
+ K EL R E+ +I ++ +L + EKEE Q K + L+ +L
Sbjct: 1633 SAAKLAELKRKAEQ------KIAAIKKQLLSQMEEKEE-----QYKKGTESHLSELNTKL 1681
Query: 330 QDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRK----K 385
Q+R E +H +E++K + S T + S A E A+ +G ++K K
Sbjct: 1682 QERERE----VHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEK 1737
Query: 386 LSLDEESSLFKQKAQQK 402
+S+ + + K+K Q+
Sbjct: 1738 ISVLQRNLTEKEKLLQR 1754
Score = 43.1 bits (100), Expect = 0.001
Identities = 66/356 (18%), Positives = 139/356 (39%), Gaps = 51/356 (14%)
Query: 18 LMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQ 77
++ + H+ E ++ + D + EL + ++EQ ++ +VD++ + +
Sbjct: 696 VLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSII-----------KEHE 744
Query: 78 HASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALL 137
+ L ++ + +L +R + + + ++ + + + +L+ A+
Sbjct: 745 VSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQ 804
Query: 138 KRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRF 197
EQ ++ EEQL Q ++ L+ E +L +A E++ C+
Sbjct: 805 SYQSATHEQTKAYEEQLAQLQQKLLDLETE-----RILLTKQVAEVEAQKKDVCT----- 854
Query: 198 NESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYE------EKEQQLVSD 251
L +Q +Q+ +++LE++N + K +K+ T YE KEQ+
Sbjct: 855 ----ELDAHKIQ---VQDLMQQLEKQNSEMEQK---VKSLTQVYESKLEDGNKEQEQTKQ 904
Query: 252 CVKELRETNAQMSR--------MTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVI 303
+ E QM +T++LS K D + EE + K+K+
Sbjct: 905 ILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAK 964
Query: 304 EKEEL--KLHLQASKDAQRQLTMELHELQDR----NMECLGMLHESQEEIKELRSR 353
E +E K L +++L EL + N + L M + I + SR
Sbjct: 965 EMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSR 1020
Score = 41.2 bits (95), Expect = 0.004
Identities = 57/229 (24%), Positives = 102/229 (44%), Gaps = 26/229 (11%)
Query: 137 LKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLR 196
LK N L EQ L+ + +V++L +L DE + + +S E S L
Sbjct: 1147 LKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLK-SSHEKSNKSLEDKSLE 1205
Query: 197 FNESFSLSQGL-LQLE--------MLQEKLKEL----EEENMALRSKACHIKTETVTYEE 243
F + LS+ L +QL+ +L+ K EL + A+ S+ H + T +
Sbjct: 1206 FKK---LSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTT--KV 1260
Query: 244 KEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVI 303
KE L+ C + E AQ+ ++TEE + + + +L +QI ++ ++ V
Sbjct: 1261 KEALLIKTCT--VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVT 1318
Query: 304 EKEELKL----HLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIK 348
EKE L+ QA+ + + +T EL + N+ + ++ E +E K
Sbjct: 1319 EKEALQKEGGNQQQAASEKESCITQLKKELSE-NINAVTLMKEELKEKK 1366
Score = 40.8 bits (94), Expect = 0.006
Identities = 70/390 (17%), Positives = 170/390 (43%), Gaps = 47/390 (12%)
Query: 31 DVCSNEDLPEVELVSL---LEEQLPQYRLKVDTLF-LYENQDWTQSPHQRQHASDALSPV 86
DVC+ D ++++ L LE+Q + KV +L +YE++ + Q
Sbjct: 851 DVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQ----------- 899
Query: 87 LAEETFRYMILGTDRVEQMTKTYN-DIDMVTHLLAERDRDLELAARIGQALLKRNHVLSE 145
E+T + ++ + + QM + +I+++T L+ ++ + + + K E
Sbjct: 900 --EQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKME 957
Query: 146 QNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQ 205
+ + +++ + + Q KK+ + ++ +E + ++ + N S +S
Sbjct: 958 KVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQAN-SAGISD 1016
Query: 206 GLLQLEMLQ-EKLKELEEEN-------MALRSKACHIKTET------VTYEEKEQQLVSD 251
+ +LE Q E+++ L E + +++ K + + E + +EKEQ+ V++
Sbjct: 1017 AVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQE-VAE 1075
Query: 252 CVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLH 311
+++ + M +E++ +E ++ L+ L Q+ + ++ +LK H
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 1135
Query: 312 LQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTG 371
L+ + + E LQ++ +E + E + ++ EL S+ T +
Sbjct: 1136 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEF---------- 1185
Query: 372 ESLAAEIEGTMRKKLSLDEESSLFKQKAQQ 401
+SL + E + SL+++S FK+ +++
Sbjct: 1186 QSLKSSHE---KSNKSLEDKSLEFKKLSEE 1212
Score = 37.4 bits (85), Expect = 0.064
Identities = 63/304 (20%), Positives = 129/304 (42%), Gaps = 35/304 (11%)
Query: 42 ELVSLLEEQLPQYRLKVDTLFL-YENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTD 100
EL S L Q +R++++ L YE Q R ++ L E++ +++
Sbjct: 1858 ELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQ-PK 1916
Query: 101 RVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQ 160
+ M +ND++ LA +R+ + + L K +L ++++ E L + +DQ
Sbjct: 1917 LLSNMEAQHNDLEFK---LAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQ 1973
Query: 161 -----VNQLQHELCKKD-----ELLRIVS--IASEESETDSSCSTPLRFNESFSLSQGLL 208
+ Q Q +L K +L+R + +A +E E + + E+ + +Q +
Sbjct: 1974 EREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELE------MTIKETINKAQEV- 2026
Query: 209 QLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTE 268
+ E+L+ +E + + K +K YEE + ++R+ Q+ E
Sbjct: 2027 EAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQL----E 2082
Query: 269 ELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHE 328
EL K + + +E + I++LQ +L + + KL Q ++ ++H
Sbjct: 2083 ELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFRE-------QIHN 2135
Query: 329 LQDR 332
L+DR
Sbjct: 2136 LEDR 2139
Score = 35.8 bits (81), Expect = 0.19
Identities = 70/343 (20%), Positives = 146/343 (42%), Gaps = 54/343 (15%)
Query: 48 EEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTK 107
E Q+ + +++L + + +Q+Q AS+ S + + + + + V M +
Sbjct: 1303 ENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCIT--QLKKELSENINAVTLMKE 1360
Query: 108 TYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHE 167
+ + L+++ DL + + +L ++ +S + +E+ + DQV L
Sbjct: 1361 ELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSF- 1419
Query: 168 LCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMAL 227
K D L + A E+ + S+ +F+E +Q + Q +KEL+ + + L
Sbjct: 1420 --KVDTLSKEKISALEQVDDWSN-----KFSEWKKKAQS--RFTQHQNTVKELQIQ-LEL 1469
Query: 228 RSKACHIKTETVTY--EEKEQQLVS-DCVK-------------------ELRETNAQMSR 265
+SK + K E + EE +QQ DC+K EL+ A++
Sbjct: 1470 KSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIME 1529
Query: 266 MTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKD------AQ 319
+ + ++ K+ E+ E L + +Q D++HK +++K + L KD +
Sbjct: 1530 LEDHITQKTIEIESLNEVLKN-YNQQKDIEHK---ELVQKLQHFQELGEEKDNRVKEAEE 1585
Query: 320 RQLTMELH--------ELQDRNMECLGM-LHESQEEIKELRSR 353
+ LT+E E + + +E + + + +EE+K L R
Sbjct: 1586 KILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDR 1628
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 57.8 bits (138), Expect = 5e-08
Identities = 86/392 (21%), Positives = 164/392 (41%), Gaps = 55/392 (14%)
Query: 44 VSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETF---RYMILGTD 100
+SL E +L + R +V L + E ++ + Q + S L +L +E + + T
Sbjct: 51 LSLTETELEELRAQVLQL-VAELEETRELAGQHEDDSLELQGLLEDERLASAQQAEVFTK 109
Query: 101 RVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQ 160
+++Q+ + LL E +++ EL I Q L + ++ E+ +
Sbjct: 110 QIQQLQGELRSLREEISLL-EHEKESELK-EIEQELHLAQAEIQSLRQAAEDSATEHESD 167
Query: 161 VNQLQHELCKK------------DELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLL 208
+ LQ +LC+ D + I S+ +E S S L ++ L + L
Sbjct: 168 IASLQEDLCRMQNELEDMERIRGDYEMEIASLRAEMEMKSSEPSGSLGLSDYSGLQEELQ 227
Query: 209 QLE----MLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMS 264
+L L E+ + L+E N +L + +++E T E+ L S + L T+A+
Sbjct: 228 ELRERYHFLNEEYRALQESNSSLTGQLADLESER-TQRATERWLQS---QTLSMTSAESQ 283
Query: 265 RMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTM 324
+ E+ +++L Q+ +++K +E E EEL+ H Q S++ QR+L
Sbjct: 284 TSEMDFLEPDPEMQLLRQQLRDAEEQMHGMKNKCQELCCELEELQHHRQVSEEEQRRL-- 341
Query: 325 ELHELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRK 384
R ++C +Q E+ L F S+ E L + + T++K
Sbjct: 342 ------QRELKC------AQNEV------------LRFQTSHSVTQNEELKSRL-CTLQK 376
Query: 385 K--LSLDEESSLFKQKAQQKRVFDTVRIANDT 414
K S DE++ L K + Q + +++ T
Sbjct: 377 KYDTSQDEQNELLKMQLQLQTELRQLKVMKST 408
Score = 46.2 bits (108), Expect = 1e-04
Identities = 66/272 (24%), Positives = 111/272 (40%), Gaps = 64/272 (23%)
Query: 148 ESLEEQLGQAFDQVNQLQHEL-CKKDELLRIV---SIASEESETDSSCSTPLRFNESFSL 203
E L+ + ++ +LQ EL C ++E+LR S+ E C+ +++ S
Sbjct: 325 EELQHHRQVSEEEQRRLQRELKCAQNEVLRFQTSHSVTQNEELKSRLCTLQKKYDTSQDE 384
Query: 204 SQGLLQLEM-LQEKLKELE-----------EENMALRSKACHIKTETVTYE-----EKEQ 246
LL++++ LQ +L++L+ E+ + R + H++ + VT E E++Q
Sbjct: 385 QNELLKMQLQLQTELRQLKVMKSTLVENQSEKELLCRLQKLHLQHQNVTCEKEKLLERQQ 444
Query: 247 QL-------------VSDCVKELRETN-------AQMSRMTEELSGKSDELIRYQEELSS 286
QL + D V +E+N AQ+ M + DEL R +
Sbjct: 445 QLQEELQCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDELERQKHMYDQ 504
Query: 287 LLSQIVDLQHKLKE----HVIEKE----------------ELKLHLQASKDAQRQLTMEL 326
L ++ Q +LKE H I ++ EL+ +AS+ QL ME
Sbjct: 505 LEQDLLLCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQEKYKASQKEMGQLQMEQ 564
Query: 327 HEL---QDRNMECLGMLHESQEEIKELRSRSG 355
EL Q R E G L E + +SG
Sbjct: 565 CELLEDQRRMQEEQGQLQEELHRLTLPLPKSG 596
Score = 35.4 bits (80), Expect = 0.24
Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 12/139 (8%)
Query: 215 EKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKS 274
E ++ EE + + K ++ +E+ QL K L A+ + EEL
Sbjct: 844 EDMERFEEMVVKVLIKLQAVQAMYQISQEEHSQLQEQMEKLL----AKQKDLKEELDACE 899
Query: 275 DELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNM 334
E E L ++ D ++++KE + EL+L QAS D Q +L + +L+
Sbjct: 900 REFKECMECLEKPMAPQND-KNEIKELQTKLRELQLQYQASMDEQGRLLVVQEQLE---- 954
Query: 335 ECLGMLHESQEEIKELRSR 353
G L QEE+++LR +
Sbjct: 955 ---GQLQCCQEELRQLREK 970
>gi|51479166 bicaudal D homolog 2 isoform 1 [Homo sapiens]
Length = 855
Score = 57.4 bits (137), Expect = 6e-08
Identities = 84/320 (26%), Positives = 133/320 (41%), Gaps = 53/320 (16%)
Query: 111 DIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLE----------EQLGQAFDQ 160
++ ++H LAE R+ AA G A+L+ H L Q E LE EQL +AF Q
Sbjct: 25 EVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELEVDYEAIRSEMEQLKEAFGQ 84
Query: 161 VNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKEL 220
+ ++ E + EES S S + Q +L+ L+ L
Sbjct: 85 AHTNHKKVAADGE-------SREESLIQESASKEQYYVRKVLELQ--TELKQLRNVLTNT 135
Query: 221 EEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRY 280
+ EN L S A +K E + +L D ++E + +R+ ++ S +E I
Sbjct: 136 QSENERLASVAQELKEINQNVEIQRGRLRDD----IKEYKFREARLLQDYSELEEENISL 191
Query: 281 QEELSSLLSQIVD---LQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNM-EC 336
Q+++S L V+ L+H++K E E L L+ DA R L E+ +R + E
Sbjct: 192 QKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLE---DAIR-----LKEISERQLEEA 243
Query: 337 LGMLHESQEEIKELRSR---------SGPTAHLYFSQSYGAFT---------GESLAAEI 378
L L +E+ LR S T+HL+ S F+ E+L
Sbjct: 244 LETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDDAAEPNNDAEALVNGF 303
Query: 379 EGTMRKKLSLDEESSLFKQK 398
E KL LD ++S K++
Sbjct: 304 EHGGLAKLPLDNKTSTPKKE 323
Score = 31.2 bits (69), Expect = 4.6
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 14/93 (15%)
Query: 213 LQEKLKELEEENMALRSKACHIK----------TETVTYEEK----EQQLVSDCVKELRE 258
L+E+LK L + A ++ K TE V+ EK +++L++ KEL++
Sbjct: 449 LREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLEKELKK 508
Query: 259 TNAQMSRMTEELSGKSDELIRYQEELSSLLSQI 291
+ LS DEL+ + EEL++L +
Sbjct: 509 VSDVAGETQGSLSVAQDELVTFSEELANLYHHV 541
>gi|21735417 bicaudal D homolog 2 isoform 2 [Homo sapiens]
Length = 824
Score = 57.4 bits (137), Expect = 6e-08
Identities = 84/320 (26%), Positives = 133/320 (41%), Gaps = 53/320 (16%)
Query: 111 DIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLE----------EQLGQAFDQ 160
++ ++H LAE R+ AA G A+L+ H L Q E LE EQL +AF Q
Sbjct: 25 EVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELEVDYEAIRSEMEQLKEAFGQ 84
Query: 161 VNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKEL 220
+ ++ E + EES S S + Q +L+ L+ L
Sbjct: 85 AHTNHKKVAADGE-------SREESLIQESASKEQYYVRKVLELQ--TELKQLRNVLTNT 135
Query: 221 EEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRY 280
+ EN L S A +K E + +L D ++E + +R+ ++ S +E I
Sbjct: 136 QSENERLASVAQELKEINQNVEIQRGRLRDD----IKEYKFREARLLQDYSELEEENISL 191
Query: 281 QEELSSLLSQIVD---LQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNM-EC 336
Q+++S L V+ L+H++K E E L L+ DA R L E+ +R + E
Sbjct: 192 QKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLE---DAIR-----LKEISERQLEEA 243
Query: 337 LGMLHESQEEIKELRSR---------SGPTAHLYFSQSYGAFT---------GESLAAEI 378
L L +E+ LR S T+HL+ S F+ E+L
Sbjct: 244 LETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDDAAEPNNDAEALVNGF 303
Query: 379 EGTMRKKLSLDEESSLFKQK 398
E KL LD ++S K++
Sbjct: 304 EHGGLAKLPLDNKTSTPKKE 323
Score = 31.2 bits (69), Expect = 4.6
Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 14/93 (15%)
Query: 213 LQEKLKELEEENMALRSKACHIK----------TETVTYEEK----EQQLVSDCVKELRE 258
L+E+LK L + A ++ K TE V+ EK +++L++ KEL++
Sbjct: 449 LREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLEKELKK 508
Query: 259 TNAQMSRMTEELSGKSDELIRYQEELSSLLSQI 291
+ LS DEL+ + EEL++L +
Sbjct: 509 VSDVAGETQGSLSVAQDELVTFSEELANLYHHV 541
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 56.2 bits (134), Expect = 1e-07
Identities = 71/355 (20%), Positives = 152/355 (42%), Gaps = 44/355 (12%)
Query: 27 ESITDVCSNEDLPEVEL------VSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHAS 80
E +TD+ S +L +L++ + YR ++ +L NQ T + +++
Sbjct: 702 EQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLH-ERNQKLTATTQKQEQII 760
Query: 81 DALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRN 140
+ ++ L + + R E + K ++ ++ + + R+ LA + GQ LL N
Sbjct: 761 NTMTQDLRGANEKLAVAEV-RAENLKKE-KEMLKLSEVRLSQQRESLLAEQRGQNLLLTN 818
Query: 141 ----------------HVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEE 184
LS Q E LE ++ +L++E+ ++ L R + + +
Sbjct: 819 LQTIQGILERSETETKQRLSSQIEKLEHEISHL---KKKLENEVEQRHTLTRNLDVQLLD 875
Query: 185 SETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEK 244
++ T L N L ++ L++ L +E + + S+ T +
Sbjct: 876 TKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSSQ------RTGKGQPS 929
Query: 245 EQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIE 304
++ V D V +LR+T Q++ + E L + + +YQ ++S L + ++ + ++ E V
Sbjct: 930 NKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTS-LEESLNKEKQVTEEV-- 986
Query: 305 KEELKLHLQASKDAQRQLTMEL-------HELQDRNMECLGMLHESQEEIKELRS 352
++ +++ L+ S + Q QL +L ELQD + + + E+K+ S
Sbjct: 987 RKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLS 1041
Score = 46.6 bits (109), Expect = 1e-04
Identities = 68/328 (20%), Positives = 134/328 (40%), Gaps = 45/328 (13%)
Query: 47 LEEQLPQYRLKVDTLFL--YENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQ 104
LE+ L Q + KV L L Q+ ++ A +L E+ R+ V Q
Sbjct: 1286 LEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQ 1345
Query: 105 MTKTYNDIDMVTHLLAERD----RDLELAARIGQ--ALLKRNHVLSEQNESLEEQLGQAF 158
D + LL+E++ R +L IG+ A + R++ N++L + L +
Sbjct: 1346 QKDP--DTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDL 1403
Query: 159 DQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLK 218
++V + + E +KD +I+ I + R+ + +L+ Q+K+
Sbjct: 1404 NKV-RTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYE------ELKAQQDKVM 1456
Query: 219 ELEEENMALRSKACHIKTETVTYEEKE-QQLVSDCVKELRETNAQMSRMTEELSGKSDEL 277
E + S H + E +E ++ ++ + + +Q+ + + LS K E
Sbjct: 1457 ETSAQ-----SSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKTLSEKETEA 1511
Query: 278 IRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQR----------------- 320
QE+ L S++ L+ L++ ++E+L+ + ++ R
Sbjct: 1512 RNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVK 1571
Query: 321 -QLTMELHELQDRNMECLGMLHESQEEI 347
QLT E EL+ RN G L + ++E+
Sbjct: 1572 DQLTKENEELKQRN----GALDQQKDEL 1595
Score = 44.3 bits (103), Expect = 5e-04
Identities = 64/241 (26%), Positives = 97/241 (40%), Gaps = 48/241 (19%)
Query: 184 ESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEE 243
E E S S NE+ L+LE L +LK L E+N
Sbjct: 56 EIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKN------------------- 96
Query: 244 KEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVD----LQHKLK 299
KE ++ D ++ +Q +R EEL + +LIR E LS L + + L KLK
Sbjct: 97 KELEIAQDRNIAIQ---SQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLNEKLK 153
Query: 300 EHVIEKEELKL---HLQAS----KDAQRQLTME---LH--------ELQDRNMECLGMLH 341
E K EL+L LQAS K +++L E LH EL+ + E L +
Sbjct: 154 ESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALGR 213
Query: 342 ESQEEIKELR----SRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQ 397
E EI EL+ ++ + L + + E L +E + K E+ + ++
Sbjct: 214 EKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEE 273
Query: 398 K 398
K
Sbjct: 274 K 274
Score = 42.7 bits (99), Expect = 0.002
Identities = 71/313 (22%), Positives = 124/313 (39%), Gaps = 64/313 (20%)
Query: 136 LLKRNHVLSEQNESLEE---QLGQAFDQVNQLQHEL-CKKDELLRI-VSIASEESETDSS 190
L++ N LS++ E L E +L + + N + EL K DEL VS+ E +
Sbjct: 127 LIRTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQE 186
Query: 191 ----------CSTPLRFNESFSLSQGL----------LQLEMLQEKLKELEEENMALRSK 230
+T L+ L+ G LE +E++ LEE+ L++
Sbjct: 187 KELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTS 246
Query: 231 ACHIKTE-----TVTYEEKEQQLVSDCVKELRETNAQMS------RMTEELSGKSDELIR 279
H++ T E KEQQ + K E NA + ++ KS+EL R
Sbjct: 247 NEHLQKHVEDLLTKLKEAKEQQASME-EKFHNELNAHIKLSNLYKSAADDSEAKSNELTR 305
Query: 280 YQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGM 339
EEL LL + + +++H++E E+ SKD +++ +E +G
Sbjct: 306 AVEELHKLLKEAGEANKAIQDHLLEVEQ-------SKD----------QMEKEMLEKIGR 348
Query: 340 LHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDE--------E 391
L + E +L S + + + A + AA + ++ + L E +
Sbjct: 349 LEKELENANDLLSATKRKGAILSEEELAAMS--PTAAAVAKIVKPGMKLTELYNAYVETQ 406
Query: 392 SSLFKQKAQQKRV 404
L +K + KR+
Sbjct: 407 DQLLLEKLENKRI 419
Score = 37.4 bits (85), Expect = 0.064
Identities = 58/263 (22%), Positives = 114/263 (43%), Gaps = 61/263 (23%)
Query: 148 ESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFN-ESFSLSQG 206
ES+E+QL + ++ +Q+E+ ++ L R + S E + C + E+ + +
Sbjct: 1027 ESMEQQLSELKKTLSSVQNEV--QEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYER 1084
Query: 207 LLQLEMLQ-EKLKELEEENMALRSKACHIKTET-----------VTYEEKEQQL---VSD 251
L L E L+ +E+ + S H++ T ++EE+E+ L VS
Sbjct: 1085 ELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKASWEERERMLKDEVSK 1144
Query: 252 CVK---ELRETNAQMSRMTEELS----------------------GKSDE-------LIR 279
CV +L + N + E+LS GKS E IR
Sbjct: 1145 CVCRCEDLEKQNRLLHDQIEKLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIR 1204
Query: 280 YQEELSSL---LSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQ------LTMELHELQ 330
++E++ ++Q+ L+++ + ++E+E LQ S +A+R+ TM HE
Sbjct: 1205 REKEIAETRFEVAQVESLRYRQRVELLERE--LQELQDSLNAEREKVQVTAKTMAQHEEL 1262
Query: 331 DRNMECLGMLHESQEEIKELRSR 353
+ E + ++ E+ + ++E + R
Sbjct: 1263 MKKTETMNVVMETNKMLREEKER 1285
Score = 37.0 bits (84), Expect = 0.084
Identities = 49/243 (20%), Positives = 94/243 (38%), Gaps = 39/243 (16%)
Query: 125 DLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHEL----CKKDELLRIVSI 180
++++A++ Q K E + L QL Q +QVN L+ L ++ +V+
Sbjct: 912 EVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTS 971
Query: 181 ASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVT 240
E + + +R N L + L++KL E+E+E
Sbjct: 972 LEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKE----------------- 1014
Query: 241 YEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKE 300
+Q+L D + + Q+S + + LS +E+ + S+ LS + +E
Sbjct: 1015 ----KQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQE 1070
Query: 301 H---VIE-----KEELKLH------LQASKDAQRQLTMELHELQDRNMECLGMLHESQEE 346
+E + EL LH LQA+K+ ++ L++ + L E +
Sbjct: 1071 QAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHLEETTQKAESQLLECKAS 1130
Query: 347 IKE 349
+E
Sbjct: 1131 WEE 1133
Score = 35.8 bits (81), Expect = 0.19
Identities = 84/405 (20%), Positives = 165/405 (40%), Gaps = 62/405 (15%)
Query: 26 SESITDVCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSP 85
+E+ +V E L + V LLE +L + + D+L + + QH
Sbjct: 1210 AETRFEVAQVESLRYRQRVELLERELQELQ---DSLNAEREKVQVTAKTMAQHEE----- 1261
Query: 86 VLAEETFRYMILGTDRV--EQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVL 143
++ + +++ T+++ E+ + D+ + + + + D+ L +++ +L
Sbjct: 1262 LMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGML 1321
Query: 144 SEQNESLEEQL-----------GQAFDQVNQLQHELCKKDEL--LRIVSIASEESETDSS 190
+ + LEE + Q D + +L + E+ RI + E +
Sbjct: 1322 QAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAE 1381
Query: 191 CSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALR----SKACHI--KTETVTYEEK 244
+ R N S + +Q L+Q L+E L ++ E ++ +K I K +T+T +K
Sbjct: 1382 IA---RSNASLTNNQNLIQ--SLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKK 1436
Query: 245 EQQLVSDCVKELR-------ETNAQMSRMTEELSGKSDELIRYQEELS-------SLLSQ 290
+ +EL+ ET+AQ S +E E+ +E L+ SL SQ
Sbjct: 1437 IGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQ 1496
Query: 291 IVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNM---ECLGMLHESQEEI 347
+ +LQ L E E L+ + + Q +L+ +LQDR + + E +E+
Sbjct: 1497 VENLQKTLSEKETEARNLQ---EQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKT 1553
Query: 348 -KELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEE 391
K + + AHL A + L E E ++ +LD++
Sbjct: 1554 RKAIVAAKSKIAHL-------AGVKDQLTKENEELKQRNGALDQQ 1591
Score = 33.5 bits (75), Expect = 0.93
Identities = 48/189 (25%), Positives = 83/189 (43%), Gaps = 31/189 (16%)
Query: 149 SLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLL 208
SL +L QA ++ +LQ + K ++ ++ + E LSQ
Sbjct: 453 SLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVK-----------DLSQ--- 498
Query: 209 QLEMLQEKLKELEEE--NMALRSKACHIKTETVTYEEKEQQLVS-DCVKELRETNAQMSR 265
Q+ +L L ELEE N +R + + + E Q LVS ++EL++ N ++
Sbjct: 499 QIRVL---LMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLV 555
Query: 266 MTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTME 325
EL R +EE + S+I +LQ KL+ + E E+L+ K Q Q+ +
Sbjct: 556 ALRELGET-----REREEQETTSSKITELQLKLESALTELEQLR------KSRQHQMQLV 604
Query: 326 LHELQDRNM 334
++ R+M
Sbjct: 605 DSIVRQRDM 613
Score = 32.0 bits (71), Expect = 2.7
Identities = 60/292 (20%), Positives = 114/292 (39%), Gaps = 57/292 (19%)
Query: 209 QLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTE 268
QLE LQE++ +L +N + ++ + + K +++ D V+ R + +
Sbjct: 696 QLEKLQEQVTDLRSQNTKISTQ--------LDFASKRYEMLQDNVEGYRREITSLHERNQ 747
Query: 269 ELSGKSDELIRYQEELSSLLSQ-IVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELH 327
+L+ + + QE++ + ++Q + KL + E LK + K ++ +L+ +
Sbjct: 748 KLTATTQK----QEQIINTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRE 803
Query: 328 EL--QDRNMECL--------GMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAE 377
L + R L G+L S+ E K+ S SQ E L E
Sbjct: 804 SLLAEQRGQNLLLTNLQTIQGILERSETETKQRLS----------SQI------EKLEHE 847
Query: 378 IEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVIM 437
I ++KKL + E + ++ DT R + ++ LL N I
Sbjct: 848 I-SHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELL----KNAQKEIA 902
Query: 438 TAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLATALHRL 489
T K S ++ + + SSQ+ G+ PS D+ + +L
Sbjct: 903 TLKQHLSNME-------------VQVASQSSQRTGKGQPSNKEDVDDLVSQL 941
Score = 31.6 bits (70), Expect = 3.5
Identities = 42/199 (21%), Positives = 84/199 (42%), Gaps = 22/199 (11%)
Query: 140 NHVLSEQNESLEEQLGQAFDQVNQLQ----HELCKKDELLRIVSIASEESETDSSCSTPL 195
N L + E L +L +A +Q ++ +EL +L + A+++SE S+ T
Sbjct: 247 NEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRA 306
Query: 196 RFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKE 255
+E L + LKE E N A++ ++ E++ + + KE
Sbjct: 307 --------------VEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKE 352
Query: 256 LRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKE----HVIEKEELKLH 311
L N +S + + S+E + ++ +++IV KL E +V +++L L
Sbjct: 353 LENANDLLSATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLE 412
Query: 312 LQASKDAQRQLTMELHELQ 330
+K + L + E++
Sbjct: 413 KLENKRINKYLDEIVKEVE 431
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 56.2 bits (134), Expect = 1e-07
Identities = 83/372 (22%), Positives = 146/372 (39%), Gaps = 49/372 (13%)
Query: 134 QALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCST 193
Q+L+++N L E+NE L L +A Q Q+ + ++ ++ EE ++C
Sbjct: 386 QSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKL 445
Query: 194 PLR----FNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACH--IKTETVTYEEKEQQ 247
L+ E L + + + LQ+ + +L +E +A + A ++ E E
Sbjct: 446 DLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETS 505
Query: 248 LVSDCV------------KELRETNAQMS-------RMTEELSGKSDELIRYQEELSSLL 288
SD KEL E N ++ +MT+ S +YQ+ + L
Sbjct: 506 RSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELE 565
Query: 289 SQIVDLQHKLKEHVIEKEELKLHLQ-ASKDAQRQLTMELHELQDRNMECLGMLHESQEEI 347
++++LQ EKEEL L LQ A KDA + +L +R + L E + +I
Sbjct: 566 LEVINLQK-------EKEELVLELQTAKKDANQA------KLSERRRK---RLQELEGQI 609
Query: 348 KELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSL----DEESSLFKQKAQQKR 403
+L+ + + L + T L EI +++ L E++ F+Q Q+K
Sbjct: 610 ADLKKKLNEQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKK- 668
Query: 404 VFDTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEE 463
D I R R + L + S ++ K E+ K L + +
Sbjct: 669 --DKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVAD 726
Query: 464 VAGSSQKMGQPG 475
+Q G G
Sbjct: 727 KRKETQSRGMEG 738
Score = 31.2 bits (69), Expect = 4.6
Identities = 59/233 (25%), Positives = 107/233 (45%), Gaps = 28/233 (12%)
Query: 127 ELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESE 186
E A R LL+ +L++ L+E+ + +L+ E+ VS SE+S
Sbjct: 758 EEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVS-ESEDSI 816
Query: 187 TDS--SCSTPLRFNES--FSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKT---ETV 239
T S T + F + L Q LL E +++ K+ E + C +K E V
Sbjct: 817 TKQIESLETEMEFRSAQIADLQQKLLDAES-EDRPKQRWENIATILEAKCALKYLIGELV 875
Query: 240 TYEEKEQQLVSDCVKELRETNAQMSRMT-EELSGKSD-------ELIR----YQEELSSL 287
+ + + +L S +K+ + + A M +M EE + ++ EL+R +QE++ L
Sbjct: 876 SSKIQVSKLESS-LKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYL 934
Query: 288 LSQIVDLQ---HKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECL 337
LSQ+ Q +L+E V EKE+ L +D + + ++ E+ ++N + L
Sbjct: 935 LSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELE---KMREVCEQNQQLL 984
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 55.5 bits (132), Expect = 2e-07
Identities = 123/575 (21%), Positives = 232/575 (40%), Gaps = 113/575 (19%)
Query: 24 RDSESITDVCSNEDLPEVELVS---LLEE---QLPQYRLKVDTLFLYENQDWTQSP---- 73
R + + D SN D E+EL LL E Q+ + ++D L L N+ SP
Sbjct: 218 RLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALL-NEKQAASPLEPK 276
Query: 74 --HQRQHASDALSPVLAEETFRYMILGTDR------VEQMTKTYNDI------------- 112
+ + +++L+ L E + L T++ + Q+++ D+
Sbjct: 277 ELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQ 336
Query: 113 --DMVTHLLAERDRD----LELAARIGQAL---LKRNHVLSEQNESLEEQLGQAFDQVNQ 163
D + L E + LE A++ + L L+ L E+NE L+ +L Q + ++Q
Sbjct: 337 LQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQ 396
Query: 164 LQ-HELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEE 222
LQ + +K E+L V LQLE L+++ L
Sbjct: 397 LQDNPPQEKGEVLGDV-----------------------------LQLETLKQEAATLAA 427
Query: 223 ENMALRSKACHIKTETVTYE----------EKEQQLVSDCVKELRETNAQMSRMTEELSG 272
N L+++ ++TE E E+E+Q +S + +L+ + + +S+ EEL
Sbjct: 428 NNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQ 487
Query: 273 KSD-ELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHE--- 328
S R +++SL S++ L +++ E LK Q +K+ Q QL L +
Sbjct: 488 ASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLK---QQAKEKQAQLAQTLQQQEQ 544
Query: 329 ----LQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRK 384
L+ + + L + ++++KE+ + T + Q A A E E ++R+
Sbjct: 545 ASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATA------AEEREASLRE 598
Query: 385 K-LSLDEESSLFKQKAQQKRVF-DTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPF 442
+ +L + +L K+KA + + +++AN+ R A + + R ++ K
Sbjct: 599 RDAALKQLEALEKEKAAKLEILQQQLQVANEARD-----SAQTSVTQAQREKAELSRKVE 653
Query: 443 ESGLQQTEDKSLLNQGSSSEEVA------GSSQKMGQPGPSGDSDLATALHRLSLRRQNY 496
E LQ + + Q + +VA S Q+ + +L +++
Sbjct: 654 E--LQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESL 711
Query: 497 LSEKQFFAEEWQRKIQVLADQKEGVSGCVTPTESL 531
K EE +R L +Q+ +S T SL
Sbjct: 712 KVTKGSLEEEKRRAADALEEQQRCISELKAETRSL 746
Score = 50.1 bits (118), Expect = 1e-05
Identities = 56/232 (24%), Positives = 111/232 (47%), Gaps = 19/232 (8%)
Query: 135 ALLKRNH-VLSEQNESLEEQ--LGQAFDQVNQLQHELCKKDELLRIVSIASEE-SETDSS 190
++LK+ H +L+E+N L E+ LG+ F +V Q EL + + A +E
Sbjct: 1438 SMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQRE 1497
Query: 191 CSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVS 250
+ R E + ++++L+E+ + +EE L ++ ++ ++ ++ + V
Sbjct: 1498 AQSTARELEVMTAKYEGAKVKVLEER-QRFQEERQKLTAQVEQLEV----FQREQTKQVE 1552
Query: 251 DCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKL 310
+ K+L +++ ++L + Q+E L +Q+ +LQ +L + E KL
Sbjct: 1553 ELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKL 1612
Query: 311 HLQASK---DAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTAH 359
++ +K DA++Q EL E Q R++E L Q+E KELR+ + H
Sbjct: 1613 QMEKAKTHYDAKKQQNQELQE-QLRSLEQL------QKENKELRAEAERLGH 1657
Score = 44.7 bits (104), Expect = 4e-04
Identities = 77/385 (20%), Positives = 150/385 (38%), Gaps = 38/385 (9%)
Query: 2 SQSQNAIFTSPTGEENLMNSNHRDSESITDVCSNEDLPEVELVSLLEEQLPQYRLKV--- 58
++ +N++ +S E +++N + E + + E E LEE+L + +
Sbjct: 1220 AERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASN 1279
Query: 59 -------DTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYND 111
+ E Q + +++ AS+ L L + R LG + K +
Sbjct: 1280 SARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQK 1339
Query: 112 IDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQ---NESLEEQLGQAFDQVNQLQHEL 168
++ L E L + + A + +EQ + E+L Q+ L+ EL
Sbjct: 1340 EQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAEL 1399
Query: 169 CKKD-ELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMAL 227
+ EL ++ + + +E + + S++ QL ML++ L EEN L
Sbjct: 1400 LRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAE-----QLSMLKKAHGLLAEENRGL 1454
Query: 228 RSKAC----HIKTETVTYEEKEQQ-----------LVSDCVKELRETNAQMSRMTEELSG 272
+A ++ E EK Q +++ +E + T ++ MT + G
Sbjct: 1455 GERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEG 1514
Query: 273 KS----DELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHE 328
+E R+QEE L +Q+ L+ +E + EEL L S A + +L
Sbjct: 1515 AKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKA 1574
Query: 329 LQDRNMECLGMLHESQEEIKELRSR 353
+Q + E Q ++ EL+++
Sbjct: 1575 VQAQGGESQQEAQRLQAQLNELQAQ 1599
Score = 42.0 bits (97), Expect = 0.003
Identities = 69/311 (22%), Positives = 125/311 (40%), Gaps = 42/311 (13%)
Query: 113 DMVTHLLAERD-RDLELAARIG--QALLKRNHVLSEQNESLEEQLGQAFDQV---NQLQH 166
+ + H L E++ +D ELA G A +K L + + L+EQL + + + Q
Sbjct: 1050 EALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQS 1109
Query: 167 ELCKKDELL--RIVSIASEESETDSSCSTPLRFNESF---------SLSQGLLQLEMLQE 215
E + E ++ ++ +E S+ + C +S S ++ LE LQ
Sbjct: 1110 EAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQG 1169
Query: 216 KLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSD 275
+L+E +E +S + E + K V D K E AQ++R +E K+
Sbjct: 1170 QLEEKAQELGHSQSALASAQRELAAFRTK----VQDHSKAEDEWKAQVARGRQEAERKNS 1225
Query: 276 ELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNME 335
+ +EE+S L Q+++ + E +ELK + A + ++L L LQ
Sbjct: 1226 LISSLEEEVSILNRQVLEKEG-------ESKELKRLVMAESEKSQKLEERLRLLQAETAS 1278
Query: 336 CLGMLHES----QEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEE 391
E +EE++ LR + E+L E+ + L +E
Sbjct: 1279 NSARAAERSSALREEVQSLREEA----------EKQRVASENLRQELTSQAERAEELGQE 1328
Query: 392 SSLFKQKAQQK 402
+++K QK
Sbjct: 1329 LKAWQEKFFQK 1339
Score = 39.3 bits (90), Expect = 0.017
Identities = 46/202 (22%), Positives = 88/202 (43%), Gaps = 29/202 (14%)
Query: 148 ESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGL 207
E+ +QLG+A +Q + E+ +++ + + + ESE + + E + SQ
Sbjct: 768 EARLQQLGEA----HQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQ-- 821
Query: 208 LQLE-----MLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQ 262
Q E M QE+L L+EE R + K + E + +S EL E +A
Sbjct: 822 -QEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHAN 880
Query: 263 MSRMTEELSGK-------SDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQAS 315
++R +++ K +D+L QE++++ ++ L+ +++ ++E
Sbjct: 881 LARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQE--------- 931
Query: 316 KDAQRQLTMELHELQDRNMECL 337
A R+L E DR E L
Sbjct: 932 -TASRELVKEPARAGDRQPEWL 952
Score = 35.4 bits (80), Expect = 0.24
Identities = 60/287 (20%), Positives = 109/287 (37%), Gaps = 47/287 (16%)
Query: 103 EQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAF---- 158
E+M T ++ + L+ + E A+R + + + Q E LEEQ G+ F
Sbjct: 907 EKMAATSKEVARLETLVRKAGEQQETASR--ELVKEPARAGDRQPEWLEEQQGRQFCSTQ 964
Query: 159 -------DQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLE 211
+ Q+ +EL + L + S ++ E R + +Q L LE
Sbjct: 965 AALQAMEREAEQMGNELERLRAAL-MESQGQQQEERGQQEREVARLTQERGRAQADLALE 1023
Query: 212 M---------LQEKLKELEEENMALRSKACHIKTETVTYEE-------------KEQQLV 249
LQ L E E L+ H TE ++ KE + +
Sbjct: 1024 KAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEEL 1083
Query: 250 SDCVKELRETNAQMSRMTEELSGKSDELIRYQE----ELSSLLSQIVDLQHKLKEHVIEK 305
VK+L+E A+ + SG E E +L +L +++ L+ + ++ +
Sbjct: 1084 RQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQA 1143
Query: 306 EELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRS 352
+ L+ L+A + ++ + L LQ G L E +E+ +S
Sbjct: 1144 DSLERSLEAERASRAERDSALETLQ-------GQLEEKAQELGHSQS 1183
Score = 30.8 bits (68), Expect = 6.0
Identities = 50/232 (21%), Positives = 88/232 (37%), Gaps = 25/232 (10%)
Query: 145 EQNESLEEQLGQAF-DQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSL 203
E ++ E Q G F +Q+ L+ E K + L+ E+ S + NE L
Sbjct: 818 EDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAEL 877
Query: 204 SQGLLQ-LEMLQEK----------LKELEEENMALRSKACHIKTETVTYEEKEQQLVSDC 252
L + L+ +QEK L L+E+ A + ++T E+++ +
Sbjct: 878 HANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASREL 937
Query: 253 VKELRETNAQMSRMTEELSGK------------SDELIRYQEELSSLLSQIVDLQHKLKE 300
VKE + EE G+ E + EL L + +++ Q + +E
Sbjct: 938 VKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQE 997
Query: 301 HVIEKE-ELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELR 351
++E E+ Q AQ L +E + M L+E + E L+
Sbjct: 998 ERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQ 1049
Score = 30.4 bits (67), Expect = 7.9
Identities = 27/100 (27%), Positives = 51/100 (51%), Gaps = 7/100 (7%)
Query: 256 LRETNAQMSRMTEELSGKS---DELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHL 312
L+ QM R+ ++L+ + DEL E LL++ D Q + + I++ L
Sbjct: 209 LQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTE-KDAQIAMMQQRIDRLALLNEK 267
Query: 313 QASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRS 352
QA+ + + EL EL+D+N LHE+ ++ ++L++
Sbjct: 268 QAASPLEPK---ELEELRDKNESLTMRLHETLKQCQDLKT 304
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 55.5 bits (132), Expect = 2e-07
Identities = 71/324 (21%), Positives = 139/324 (42%), Gaps = 38/324 (11%)
Query: 40 EVELVSLLEEQLP--QYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEET-FRYMI 96
E E +L QL Q + +++ ++++ Q+ Q D+L L ET R +
Sbjct: 1554 EHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEV 1613
Query: 97 LGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQ----NESLEE 152
L + +M N++++ + + + Q+LLK + + N+ L+E
Sbjct: 1614 LRVKK--KMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKE 1671
Query: 153 QLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEM 212
+ + N LQ EL +EL +V E S+ L + E+
Sbjct: 1672 NIAIVERRNNLLQAEL---EELRAVV--------------------EQTERSRKLAEQEL 1708
Query: 213 LQ--EKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDC---VKELRETNAQMSRMT 267
++ E+++ L +N +L ++ ++++ + + ++ V +C ++ ++ + M
Sbjct: 1709 IETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMA 1768
Query: 268 EELSGKSDELIRYQEELSSLLSQIVDLQHKLKE-HVIEKEELKLHLQASKDAQRQLTMEL 326
EEL + D + ++ I DLQH+L E I + K LQ + R+L EL
Sbjct: 1769 EELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGEL 1828
Query: 327 HELQDRNMECLGMLHESQEEIKEL 350
Q RN E + + +S+ IKEL
Sbjct: 1829 EAEQKRNAESVKGMRKSERRIKEL 1852
Score = 43.5 bits (101), Expect = 9e-04
Identities = 95/467 (20%), Positives = 182/467 (38%), Gaps = 85/467 (18%)
Query: 47 LEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHAS---DALSPVLAEETFRYMILGTDRVE 103
LE++ +++L++D D T + Q A + +S L ++ Y + ++E
Sbjct: 1219 LEKEKSEFKLELD--------DVTSNMEQIIKAKANLEKVSRTLEDQANEYRV----KLE 1266
Query: 104 QMTKTYNDIDMVTHLL----AERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFD 159
+ ++ ND L E R LE + L + ++Q E L+ QL +
Sbjct: 1267 EAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGK 1326
Query: 160 QVNQLQHELCK------------------KDELLRIVSIASEES-------ETDSSCSTP 194
N L H L K EL R++S A+ E ETD+ T
Sbjct: 1327 AKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTE 1386
Query: 195 LRFNESFSLSQGLLQ----LEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVS 250
L+Q L +E + K LE+ L+++ + + E+ +
Sbjct: 1387 ELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDV----ERSNAAAA 1442
Query: 251 DCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKL 310
K+ R + ++ ++ EL Q+E SL +++ L++ +E +
Sbjct: 1443 ALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLE------- 1495
Query: 311 HLQASKDAQRQLTMELHELQDRNMECLGMLHESQE-----EIKELRSRSG-PTAHLYFSQ 364
HL+ K + L E+ +L ++ E +HE ++ E+++L +S A
Sbjct: 1496 HLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEEAEASLEH 1555
Query: 365 SYGAFTGESLA-AEIEGTMRKKLSLDEESSLFKQKAQQKRVFDTVRIANDTRGRSISFPA 423
G L +I+ + +KL+ +++ + + K +RV D+++ + D RS
Sbjct: 1556 EEGKILRAQLEFNQIKAEIERKLA-EKDEEMEQAKRNHQRVVDSLQTSLDAETRS----- 1609
Query: 424 LLPIPGSNRSSVIMTAKPFESGLQQTEDKSLLNQGSSSEEVAGSSQK 470
R+ V+ K E L + E Q S + +A +QK
Sbjct: 1610 --------RNEVLRVKKKMEGDLNEME-----IQLSHANRMAAEAQK 1643
Score = 42.4 bits (98), Expect = 0.002
Identities = 58/323 (17%), Positives = 144/323 (44%), Gaps = 35/323 (10%)
Query: 102 VEQMTKTYNDIDMVTHLLAERDRDL-ELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQ 160
++ + T ++ H + ++L E A + + + K L+++ ++L+E QA D
Sbjct: 956 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAK----LTKEKKALQEAHQQALDD 1011
Query: 161 VNQLQHELCKKDELLRI-VSIASEESETDSSCSTPLRFNESFSLSQGLLQ--LEMLQEKL 217
LQ E K + L + V + + + + S + ++ L+ L++ QE +
Sbjct: 1012 ---LQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESI 1068
Query: 218 KELEEENMAL----RSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGK 273
+LE + + L + K I + E+ EQ L K+L+E A++ + EEL +
Sbjct: 1069 MDLENDKLQLEEKLKKKEFDINQQNSKIED-EQVLALQLQKKLKENQARIEELEEELEAE 1127
Query: 274 SDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQ-RQLTMELHE---- 328
+ ++ S L ++ ++ +L+E +++ + ++A+ +++ +L E
Sbjct: 1128 RTARAKVEKLRSDLSRELEEISERLEE-AGGATSVQIEMNKKREAEFQKMRRDLEEATLQ 1186
Query: 329 -------LQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGT 381
L+ ++ + + L E + ++ ++ + L +S + + + +E
Sbjct: 1187 HEATAAALRKKHADSVAELGEQIDNLQRVKQK------LEKEKSEFKLELDDVTSNMEQI 1240
Query: 382 MRKKLSLDEESSLFKQKAQQKRV 404
++ K +L++ S + +A + RV
Sbjct: 1241 IKAKANLEKVSRTLEDQANEYRV 1263
Score = 41.6 bits (96), Expect = 0.003
Identities = 53/256 (20%), Positives = 116/256 (45%), Gaps = 27/256 (10%)
Query: 111 DIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCK 170
+++ + ++ + +R +LA + +R +L QN SL Q + + QLQ E+ +
Sbjct: 1686 ELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMESDLTQLQSEVEE 1745
Query: 171 KDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKEL-----EEENM 225
+ R ++++ TD++ E + + + +++ +K+L E E +
Sbjct: 1746 AVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQI 1805
Query: 226 ALRSKACHI-KTETVTYE-----EKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIR 279
AL+ + K E E E EQ+ ++ VK +R++ ++ +T + L+R
Sbjct: 1806 ALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLR 1865
Query: 280 YQEELSSLLSQIVD-LQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLG 338
Q+ +VD LQ K+K + + EE + + R++ EL E ++R
Sbjct: 1866 LQD--------LVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEER------ 1911
Query: 339 MLHESQEEIKELRSRS 354
++ ++ +LR++S
Sbjct: 1912 -ADIAESQVNKLRAKS 1926
Score = 35.4 bits (80), Expect = 0.24
Identities = 61/297 (20%), Positives = 121/297 (40%), Gaps = 29/297 (9%)
Query: 107 KTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQH 166
K D+ + + + + D ++ + L K+ +++QN +E++ QV LQ
Sbjct: 1056 KLEGDLKLTQESIMDLEND---KLQLEEKLKKKEFDINQQNSKIEDE------QVLALQL 1106
Query: 167 ELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMA 226
+ K+ RI + EE E + + + S LS+ +LE + E+L+E
Sbjct: 1107 QKKLKENQARIEEL-EEELEAERTARAKVEKLRS-DLSR---ELEEISERLEEA------ 1155
Query: 227 LRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGK-SDELIRYQEELS 285
A ++ E E E Q + ++L E Q L K +D + E++
Sbjct: 1156 --GGATSVQIEMNKKREAEFQKMR---RDLEEATLQHEATAAALRKKHADSVAELGEQID 1210
Query: 286 SLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQE 345
+L L+ + E +E +++ +++ A+ L L+D+ E L E+Q
Sbjct: 1211 NLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQR 1270
Query: 346 EIKELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQK 402
+ + ++ A L A E A I R KLS ++ K++ +++
Sbjct: 1271 SLNDFTTQ---RAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEE 1324
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
sapiens]
Length = 2346
Score = 55.1 bits (131), Expect = 3e-07
Identities = 48/175 (27%), Positives = 82/175 (46%), Gaps = 17/175 (9%)
Query: 150 LEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQ 209
LEE LG+ + +L+ +C D L E+ E + + R + S SQGL
Sbjct: 1844 LEEHLGEIRNLRQRLEESICINDRL-------REQLEHRLTSTARGRGSTSNFYSQGLES 1896
Query: 210 LEMLQEKLKELEEENMALRSKACHIKTE-TVTYEEKEQQLVS------DCVKELRETNAQ 262
+ L + + L E+N L+++ H+ E + E + L+S + KEL +
Sbjct: 1897 IPQLCNENRVLREDNRRLQAQLSHVSREHSQETESLREALLSSRSHLQELEKELEHQKVE 1956
Query: 263 MSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHK---LKEHVIEKEELKLHLQA 314
++ E+L K E++ ++EE SL LQHK L++ EK++L LQ+
Sbjct: 1957 RQQLLEDLREKQQEVLHFREERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQS 2011
Score = 46.2 bits (108), Expect = 1e-04
Identities = 58/249 (23%), Positives = 102/249 (40%), Gaps = 15/249 (6%)
Query: 100 DRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFD 159
+R ++ Y ++ LL E R + A AL++ E N L E+L
Sbjct: 93 ERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAE---KECNLELSEKLKGVTK 149
Query: 160 QVNQLQHELCKKDELLRIVSIASEE-SETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLK 218
+ + K D+ ++ + E + S + R E LS+ QL L E+
Sbjct: 150 NWEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQ--LSREKQQLLHLLEEPT 207
Query: 219 ELEEENMA---LRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSD 275
+E + M L+ + + T+T + +++ +++++T A + E+L+ S
Sbjct: 208 SMEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSY 267
Query: 276 ELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNME 335
EL QE I +L+ LK E EEL ++ D +L LH+ Q
Sbjct: 268 ELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQ----- 322
Query: 336 CLGMLHESQ 344
LG LH S+
Sbjct: 323 -LGQLHSSE 330
Score = 42.0 bits (97), Expect = 0.003
Identities = 98/472 (20%), Positives = 178/472 (37%), Gaps = 78/472 (16%)
Query: 114 MVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQ----LQHELC 169
M+ LL++R++ + Q LL+ +++++ E+L QA + N L+ L
Sbjct: 626 MLQDLLSDRNKQVLEHEMEIQGLLQSVSTREQESQAAAEKLVQALMERNSELQALRQYLG 685
Query: 170 KKDELLRIVSIASEESE-TDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALR 228
+D L+ I+++++E T + C QG +Q+ + +E++++
Sbjct: 686 GRDSLMSQAPISNQQAEVTPTGCLGK-------QTDQGSMQIPSRDDSTSLTAKEDVSIP 738
Query: 229 SKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLL 288
+TV EKE +S EEL + + Q ELS+L
Sbjct: 739 RSTLG-DLDTVAGLEKE-----------------LSNAKEELELMAKKERESQMELSALQ 780
Query: 289 SQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIK 348
S + + +L+ + E L ++Q +D + L M+L + +D + + +E+
Sbjct: 781 SMMAVQEEELQVQAADMESLTRNIQIKEDLIKDLQMQLVDPED-----IPAMERLTQEVL 835
Query: 349 ELRSRSGPTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEE--------SSLFKQKAQ 400
LR + Q + L +EG + ++ L+E SSL K A
Sbjct: 836 LLREKVASVESQ--GQEISGNRRQQLLLMLEGLVDERSRLNEALQAERQLYSSLVKFHAH 893
Query: 401 QKRVFDTVRIANDTRGRSISFPALLPIPGS-----NRSSVIMTAKPFESGLQQTEDKSLL 455
+ + + G + L + G NR + +G TED S
Sbjct: 894 PESSERDRTLQVELEGAQVLRSRLEEVLGRSLERLNRLETLAAIGGAAAG-DDTEDTSTE 952
Query: 456 NQGSSSEEVAGSSQK--------------------MGQPGP-SGDSDLATALHRLSLRRQ 494
S EE A S + P P GDS+ L LR +
Sbjct: 953 FTDSIEEEAAHHSHQQLVKVALEKSLATVETQNPSFSPPSPMGGDSNRCLQEEMLHLRAE 1012
Query: 495 --NYLSEKQFFAEEWQR-KIQVLADQKEGVSGCVTPTESLASLCTTQSEITD 543
+L EK+ EE + K Q+ ++ G S ++ SLC +E+ +
Sbjct: 1013 FHQHLEEKRKAEEELKELKAQI---EEAGFSSVSHIRNTMLSLCLENAELKE 1061
Score = 41.6 bits (96), Expect = 0.003
Identities = 84/396 (21%), Positives = 150/396 (37%), Gaps = 54/396 (13%)
Query: 47 LEEQLPQYRLKVDTLF-LYENQDWTQSP-----HQRQ----HASDALSPVLAEETFRYMI 96
L+E L + + L+ + E Q+ T + HQ Q H+S+ SP + +
Sbjct: 286 LKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQLHSSEGTSPA------QQQV 339
Query: 97 LGTDRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQ 156
D + + +I + ++ +++R L A + Q + H +Q E+ + +
Sbjct: 340 ALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQE 399
Query: 157 AFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQL------ 210
+ QLQ EL K + LR A + +E + N S S + LLQ
Sbjct: 400 LRKALQQLQEELQNKSQQLRAWE-AEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQ 458
Query: 211 ------------EMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRE 258
EML EKL++ + +A K + +EKE + + V RE
Sbjct: 459 YRDNSDKTLEANEMLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAV---RE 515
Query: 259 TNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDA 318
+ + R+ + LS + + L + ++ L + KEE++ +
Sbjct: 516 RDHDLERLRDVLSSNEATMQSMESLLRAKGLEVEQLSTTCQNLQWLKEEMETKFSRWQKE 575
Query: 319 QRQLTMELH-ELQDRNME-------CLGMLHESQEEIKE-----LRSRSGPTAHLYFSQS 365
Q + +L L DRN E L L Q EI E L+ + L ++
Sbjct: 576 QESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKERMLQDLLSDRN 635
Query: 366 YGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQ 401
E EI+G ++ + ++ES +K Q
Sbjct: 636 KQVLEHE---MEIQGLLQSVSTREQESQAAAEKLVQ 668
Score = 34.7 bits (78), Expect = 0.42
Identities = 54/247 (21%), Positives = 100/247 (40%), Gaps = 35/247 (14%)
Query: 211 EMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEEL 270
++L+E L E+ L C E+ E +L S + T+ S+ E +
Sbjct: 1842 DLLEEHLGEIRNLRQRLEESIC---INDRLREQLEHRLTSTA-RGRGSTSNFYSQGLESI 1897
Query: 271 SGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQ 330
+E +E+ L +Q L H +EH E E L+ L +S+ ++L EL +
Sbjct: 1898 PQLCNENRVLREDNRRLQAQ---LSHVSREHSQETESLREALLSSRSHLQELEKELEHQK 1954
Query: 331 DRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLA-AEIEGTMRKKLSL- 388
+ L L E Q+E+ R E L+ E + ++ KL L
Sbjct: 1955 VERQQLLEDLREKQQEVLHFRE-------------------ERLSLQENDSRLQHKLVLL 1995
Query: 389 ----DEESSLFKQKAQQKRVFDTVRIANDTRG-RSISFPALLPIP-GSNRSSVIMTAKPF 442
+E+ LF+ + ++++ + N +G ++ S A IP S+ S ++ +
Sbjct: 1996 QQQCEEKQQLFESLQSELQIYEAL-YGNSKKGLKAYSLDACHQIPLSSDLSHLVAEVRAL 2054
Query: 443 ESGLQQT 449
L+Q+
Sbjct: 2055 RGQLEQS 2061
Score = 33.1 bits (74), Expect = 1.2
Identities = 51/223 (22%), Positives = 95/223 (42%), Gaps = 29/223 (13%)
Query: 147 NESLEEQLGQAFDQVNQLQHELCKKDELLRIV--SIASEESETDSSCSTPLRFNESFSLS 204
N+ L+E+L + ++ Q K+D ++ + ++ S E ET+ N++ +
Sbjct: 255 NKILQEKLNEMSYELKCAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKL 314
Query: 205 QGLLQLEML------------QEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVS-- 250
+ +L L Q+++ L+ ++ S+ K + V +KE+QL
Sbjct: 315 REMLHQSQLGQLHSSEGTSPAQQQVALLDLQSALFCSQLEIQKLQRVV-RQKERQLADAK 373
Query: 251 DCVKELRETNAQMSRMTEELSGKSDELIR-----YQEELSSLLSQIVDLQHKLKEHVIEK 305
CV+ + E A S +E S K ++ +R QEEL + Q+ + + + +
Sbjct: 374 QCVQFV-EAAAHESEQQKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQ 432
Query: 306 EELKLHLQASKDAQRQLTMELHEL------QDRNMECLGMLHE 342
E+ HL S + QL E EL D+ +E ML E
Sbjct: 433 EQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLE 475
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 55.1 bits (131), Expect = 3e-07
Identities = 82/419 (19%), Positives = 178/419 (42%), Gaps = 54/419 (12%)
Query: 148 ESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGL 207
+S + + F +++ + L + D+L ++ EE + + S L ++ LSQ
Sbjct: 1819 KSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQIS 1878
Query: 208 L---QLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMS 264
+L+MLQE++ ++ N ++ + + T EE++ L + +L E N +
Sbjct: 1879 TKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIG 1938
Query: 265 RMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHV-----IEKEELKLHLQASKDAQ 319
++++ + + E+ +L + +L+ + ++ V +E E K +L+ + AQ
Sbjct: 1939 NYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQ 1998
Query: 320 RQLTMELH--ELQDRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGESLAAE 377
++ + H ELQ+ +L E Q+E+K+L+ + + + A A E
Sbjct: 1999 KEPGNKSHAKELQE-------LLKEKQQEVKQLQKDC-----IRYQEKISALERTVKALE 2046
Query: 378 -IEGTMRKKLSLDEES---SLFKQKAQQKRVFDTVRIANDTRGRSISFPA----LLPIPG 429
++ +K L + +E+ ++ +K Q + + +DT+ + A L
Sbjct: 2047 FVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2106
Query: 430 SNRSSVIMTAK----PFESGLQQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLATA 485
SN+ SV K E L+Q E+K L + + E++ A
Sbjct: 2107 SNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKL-------------------DA 2147
Query: 486 LHRLSLRRQNYLSEKQFFAEEWQRKIQVLADQKEG-VSGCVTPTESLASLCTTQSEITD 543
L R + + + E Q + +++Q L + + V+ T+S++SL + + D
Sbjct: 2148 LRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVID 2206
Score = 53.9 bits (128), Expect = 7e-07
Identities = 66/346 (19%), Positives = 155/346 (44%), Gaps = 39/346 (11%)
Query: 42 ELVSLLEEQLPQYRLKVDTLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDR 101
E V L+EQ+ + L++++L ++ + +Q + + E R + D
Sbjct: 1337 EEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDE 1396
Query: 102 VEQM-TKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQ 160
++++ +K D+ ++ L+E++ L +I ++++ ++ + LE Q + ++
Sbjct: 1397 LQKLISKKEEDVSYLSGQLSEKEAAL---TKIQTEIIEQEDLIKALHTQLEMQAKEHDER 1453
Query: 161 VNQLQHELC---KKDELLRIVSIASEESETDSSCSTPLR---------FNESFSLSQGLL 208
+ QLQ ELC +K E + S A ++ + + R E SL++G
Sbjct: 1454 IKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARG-- 1511
Query: 209 QLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNA------Q 262
+E L + L ++E + A + + +E+ +L+++ + L E +
Sbjct: 1512 TIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCES 1571
Query: 263 MSRMTEELSGKSDELIRYQEEL-SSLLSQIVDLQHK----LKEHVI----------EKEE 307
+ E L+ ++L++ E L SS +++ + Q K KE+ I E E
Sbjct: 1572 LKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAER 1631
Query: 308 LKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSR 353
++ ++A + +++L +L + E L E+++E++E++ +
Sbjct: 1632 IQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEK 1677
Score = 53.1 bits (126), Expect = 1e-06
Identities = 84/378 (22%), Positives = 157/378 (41%), Gaps = 56/378 (14%)
Query: 100 DRVEQMTKTYNDIDMVTHLLAERDR-DLELAARIGQALLKRNHVLSEQNESLEEQLGQAF 158
+R++Q+ ++ + E R ++ ++ AL+ R L E N+SL+E+L A
Sbjct: 1452 ERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKE-NKSLQEELSLAR 1510
Query: 159 DQVNQLQHELC-----------KKDELL-RIVSIASEESETDSSCSTPLRFNESFSLSQG 206
+ +L L +KD +L R+ + E + + L N+S S S
Sbjct: 1511 GTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSCE 1570
Query: 207 LLQL--EMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSD---CVKELRETNA 261
L+L E L E ++L +E +L+S TE ++EK ++L + ++ +
Sbjct: 1571 SLKLALEGLTEDKEKLVKEIESLKSSKIAESTE---WQEKHKELQKEYEILLQSYENVSN 1627
Query: 262 QMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQ 321
+ R+ + E +L S + + + +L+E E EE+K ++ +++Q
Sbjct: 1628 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQ 1687
Query: 322 LTMELHELQDR-----------NMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFT 370
+EL E DR EC+ L S +KE R Y
Sbjct: 1688 KILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELER--------VKMEY---- 1735
Query: 371 GESLAAEIEGTMRKKLSLDEESSLFKQK-----AQQKRVFDTVRIANDTRGRSISFPALL 425
E+L+ + + M +K SL EE K + ++Q + T + N T +++
Sbjct: 1736 -ETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQT---NVTEEGTQ 1791
Query: 426 PIPG--SNRSSVIMTAKP 441
IPG + S+ M+ +P
Sbjct: 1792 SIPGETEEQDSLSMSTRP 1809
Score = 51.6 bits (122), Expect = 3e-06
Identities = 52/231 (22%), Positives = 103/231 (44%), Gaps = 33/231 (14%)
Query: 149 SLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLL 208
S EE++ ++ +++H+L +K+EL+ + +++ + + E + Q L
Sbjct: 139 STEEEM-----EIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQ 193
Query: 209 QLE----MLQEKLKELEEENMA---LRSKACHIKTETVTYEEKEQQLV------SDCVKE 255
+ E LQ +L + + E A +R K +T+ +E++ QLV ++ ++
Sbjct: 194 EKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQK 253
Query: 256 LRETNAQMSRMTEELSGKSDELIRYQEELSS------LLSQIVDLQHKLKEH-------V 302
LR ++ E L G++ + Q+EL++ +LSQ LQ EH
Sbjct: 254 LRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQ--QLQQMEAEHNTLRNTVE 311
Query: 303 IEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSR 353
E+EE K+ L+ + + + H LQ+ L ++ + EL SR
Sbjct: 312 TEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESR 362
Score = 50.1 bits (118), Expect = 1e-05
Identities = 83/412 (20%), Positives = 164/412 (39%), Gaps = 67/412 (16%)
Query: 2 SQSQNAIFTSPTGEENLMNSNHRDSESITDV--CSNEDLPEVELVSLLEEQLPQYRLKVD 59
+Q + T P EE L + +E ++ ++ + EL+S L+ QL Q + +
Sbjct: 116 AQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQP 175
Query: 60 TLFLYENQDWTQSPHQRQHASDALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLL 119
E +++ Q Q + +S + A+ + ++ Q D T +
Sbjct: 176 AQSSTEMEEFVMMKQQLQEKEEFISTLQAQLSQTQ----AEQAAQQVVREKDARFETQVR 231
Query: 120 AERDRDLELA--ARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRI 177
D L+L A + + ++ VL + E EE L V+ LQ EL ++ +I
Sbjct: 232 LHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQI 291
Query: 178 VS--IASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLK----------------- 218
+S + E+E ++ +T E + ++LE+ + KL
Sbjct: 292 LSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQ 351
Query: 219 ------ELEEENMALRSK-ACHIKTET---VTYEEKEQQLVSDC-------VKELRETNA 261
ELE AL K ++ +T ++ ++ Q+L S C K L++ N
Sbjct: 352 AGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNE 411
Query: 262 QMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHK------------------LKEHVI 303
Q + + + D+L + +E+S L+++ QH+ +E++
Sbjct: 412 QAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIA 471
Query: 304 EKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSG 355
++ + L+ K A ++EL EL+ N + SQ + E ++R+G
Sbjct: 472 SLQKRVVELENEKGALLLSSIELEELKAENEKL-----SSQITLLEAQNRTG 518
Score = 49.3 bits (116), Expect = 2e-05
Identities = 90/407 (22%), Positives = 165/407 (40%), Gaps = 85/407 (20%)
Query: 32 VCSNEDLPEVELVSLLEEQLPQYRLKVDTLFLYENQ---------DWTQSPHQRQHASDA 82
VC EL+S LEE Y + L E++ D + S + +
Sbjct: 2278 VCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGN 2337
Query: 83 LSPVLAEET-------FRYMILGTDRV---EQMTKTYNDIDMVTHLLAERDRDLELAARI 132
L ++ ++ F Y L TD E ++ + +I+M + E A ++
Sbjct: 2338 LEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQV 2397
Query: 133 GQALLKRNH---------VLSEQNES---LEEQLGQAFDQVNQLQHEL--CKKDELLRIV 178
A L++ H +LS++ E LEE+ +A D+ NQL L KK+ +
Sbjct: 2398 AIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENI---- 2453
Query: 179 SIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTET 238
++++ DS F +S S Q + + ++LEE ++++ + + E
Sbjct: 2454 ---QQKAQLDS-------FVKSMSSLQN--DRDRIVGDYQQLEERHLSIILEKDQLIQEA 2501
Query: 239 VTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKL 298
K ++ E+R + M + E + ELI+Y+E+L+ +++ I D Q
Sbjct: 2502 AAENNKLKE-------EIRGLRSHMDDLNSENAKLDAELIQYREDLNQVIT-IKDSQ--- 2550
Query: 299 KEHVIEKEELKLHLQASKDAQR---QLTMELHELQDRNMECLGMLHESQEEIKELRSRSG 355
+K+ L++ LQ +K+ + +L +L E ++ N + + QEE ++L
Sbjct: 2551 -----QKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEI- 2604
Query: 356 PTAHLYFSQSYGAFTGESLAAEIEGTMRKKLSLDEESSLFKQKAQQK 402
ESL I R+ +L EE +L AQ K
Sbjct: 2605 ----------------ESLKVSISQLTRQVTALQEEGTLGLYHAQLK 2635
Score = 47.4 bits (111), Expect = 6e-05
Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 26/252 (10%)
Query: 118 LLAERDRDLELAARIGQALLKRNHVLSEQNES---LEEQLGQAFDQVNQLQHELCKKD-- 172
L E++++ +L ++ +AL R +L + E L E+L Q D N+LQ + ++
Sbjct: 1167 LALEKEKE-QLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE 1225
Query: 173 -----ELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMAL 227
+ LR + I ES ST + ES S + GL E K E L
Sbjct: 1226 NENIGDQLRQLQIQVRESIDGKLPSTDQQ--ESCSSTPGL---EEPLFKATEQHHTQPVL 1280
Query: 228 RSKAC-----HIKTETVTYEEKEQQLVSDCVKELR----ETNAQMSRMTEELSGKSDELI 278
S C H + + + +KE+ E ++S T EL+ KS+E+
Sbjct: 1281 ESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKKSEEVF 1340
Query: 279 RYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLG 338
+ QE+++ +I L+ E + E L+ L++S+ Q L ELQ + E
Sbjct: 1341 QLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQ-LQIAGLEHLRELQPKLDELQK 1399
Query: 339 MLHESQEEIKEL 350
++ + +E++ L
Sbjct: 1400 LISKKEEDVSYL 1411
Score = 47.4 bits (111), Expect = 6e-05
Identities = 65/255 (25%), Positives = 103/255 (40%), Gaps = 41/255 (16%)
Query: 127 ELAARIGQALLKRNH--VLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEE 184
ELA Q LL R +LSE S+ + + +L +L KDE L +S E+
Sbjct: 2767 ELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLED 2826
Query: 185 SETDSSCSTPLRFNESFSLSQGLLQLEMLQ-----EKLKELEEENMALRSKACHIKTETV 239
S +SFS + LQ E EK ++ EE ++ E
Sbjct: 2827 SYNQV---------QSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSPAEVQ 2877
Query: 240 TYEEKEQQLVSD---CVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQH 296
+ ++ L +D +KEL+ Q ++ +E++ EL L +Q+ + Q
Sbjct: 2878 SLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT-----------ELHPLKAQLQEYQD 2926
Query: 297 KLKEHVIEKEELKLHLQASKDAQRQLTM-----ELHELQDRNMECLGM------LHESQE 345
K K I +EEL+ + + QL M E+HE + + + + L Q
Sbjct: 2927 KTKAFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQN 2986
Query: 346 EIKELRSRSGPTAHL 360
I+ELRS S T L
Sbjct: 2987 LIRELRSSSSQTQPL 3001
Score = 44.3 bits (103), Expect = 5e-04
Identities = 61/283 (21%), Positives = 116/283 (40%), Gaps = 37/283 (13%)
Query: 103 EQMTKTYNDIDMVTHL----------LAERDR----DLELAARIGQALLKRNHVLSEQNE 148
+Q+ ++ MVT L LAE +R D E L ++ H LS + +
Sbjct: 747 DQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAK 806
Query: 149 SLEEQLGQAFDQVNQLQHELCKKDELLRIVS--IASEESETDSSCSTPLRFNESFS-LSQ 205
S + ++ ++++ +Q + ++ L+R + + ++ESE + LSQ
Sbjct: 807 SKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQ 866
Query: 206 GLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQL------VSDCVKELRET 259
L Q E+ K+ +L L K ++T T EEK+QQ+ +++ + +L E
Sbjct: 867 ALSQKELEITKMDQL------LLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEE 920
Query: 260 NAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHV--------IEKEELKLH 311
+ + L + + L R +E + + ++ LK++ I KEEL+
Sbjct: 921 KFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHE 980
Query: 312 LQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRS 354
K Q +L E L + +EE+ L+ S
Sbjct: 981 FDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDES 1023
Score = 42.7 bits (99), Expect = 0.002
Identities = 66/314 (21%), Positives = 124/314 (39%), Gaps = 79/314 (25%)
Query: 100 DRVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQAL---LKRNHVLSEQNESLEEQLGQ 156
D ++ + ++ + V + ++D DLE R+ QA LK + E+ ++L +
Sbjct: 2097 DNLKLKKELQSNKESVKSQMKQKDEDLE--RRLEQAEEKHLKEKKNMQEKLDALRREKVH 2154
Query: 157 AFDQVNQLQHELCKKDELLRIV----------------SIASEESETDSSCSTPLRFNES 200
+ + ++Q L KKD+ ++ + S++S + + D ++
Sbjct: 2155 LEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERK 2214
Query: 201 FS-----------------------LSQGLLQLEMLQEKLKELEEENMALRSKACHIKTE 237
FS L Q + +E L+ + LE + SKA
Sbjct: 2215 FSDAIQSKEEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKA------ 2268
Query: 238 TVTYEEKEQQLVSDCVK-ELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQH 296
E + QQ V D ++ E +E +Q+ +EL + + EL SL Q+ DL +
Sbjct: 2269 --QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSN 2326
Query: 297 KLKEHVIEK---------------------EELKLHLQASKDAQRQLTMELH-ELQDRNM 334
L++ +K E+L+ LQAS R+LT LH E+ +
Sbjct: 2327 SLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQAS----RELTSRLHEEINMKEQ 2382
Query: 335 ECLGMLHESQEEIK 348
+ + +L +E I+
Sbjct: 2383 KIISLLSGKEEAIQ 2396
Score = 41.6 bits (96), Expect = 0.003
Identities = 89/442 (20%), Positives = 175/442 (39%), Gaps = 67/442 (15%)
Query: 101 RVEQMTKTYNDIDMVTHLLAERDRDLELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQ 160
+++Q + N + L E + E R AL + LS++ ESL+ + Q Q
Sbjct: 2558 QLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQ 2617
Query: 161 VNQLQHE----------LCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQL 210
V LQ E K++E+ R+ ++ S + + L + + ++
Sbjct: 2618 VTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQK----EAAKKV 2673
Query: 211 EMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEEL 270
+++KLK+ E L A ++ ET T EE+ V++ ++L E ++ +T+E
Sbjct: 2674 GEIEDKLKK---ELKHLHHDAGIMRNETETAEER----VAELARDLVEMEQKLLMVTKEN 2726
Query: 271 SGKSDELIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQ 330
G + ++ + +SSL + ++H E+ + L+ DA + +L E
Sbjct: 2727 KGLTAQIQSFGRSMSSLQNS--------RDHANEELD---ELKRKYDASLKELAQLKEQG 2775
Query: 331 DRNMECLGMLHESQEEIKELRSRSGPTAHLYFSQSYGAFTGES---LAAEIEGTMRKKLS 387
N E +L E+ + S +HL E L++++E + + S
Sbjct: 2776 LLNRERDALLSETAFSMNSTEENS--LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQS 2833
Query: 388 LDEE-SSLFKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGL 446
+ +SL ++ + R + + + RS + P+ P + + + K S L
Sbjct: 2834 FSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPSTSP-------AEVQSLKKAMSSL 2886
Query: 447 QQTEDKSLLNQGSSSEEVAGSSQKMGQPGPSGDSDLATALHRLSLRRQNYLSEK---QFF 503
Q D+ L + ++ +Q++ T LH L + Q Y + Q
Sbjct: 2887 QNDRDRLLKELKNLQQQYLQINQEI------------TELHPLKAQLQEYQDKTKAFQIM 2934
Query: 504 AEE-------WQRKIQVLADQK 518
EE WQ ++ L +K
Sbjct: 2935 QEELRQENLSWQHELHQLRMEK 2956
Score = 37.4 bits (85), Expect = 0.064
Identities = 80/393 (20%), Positives = 148/393 (37%), Gaps = 68/393 (17%)
Query: 178 VSIASEESETDSSCST-----PLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKAC 232
V + S + + D S S +E L +L+LE+ K +E+ E+N+ ++
Sbjct: 659 VELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKA--- 715
Query: 233 HIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELS---SLLS 289
KE ++ ++E ++ S LS + D+L+ +ELS L +
Sbjct: 716 -----------KEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRA 764
Query: 290 QIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHEL------QDRNMECL-GMLHE 342
Q+ L+ L E + + +L ++ LT ++H L +D +E L L +
Sbjct: 765 QVKQLEMNLAE---AERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDD 821
Query: 343 SQEEIKE----LRSRSGPTAHLYFSQSYGAFTGESLAAEIE----GTMRKKLSLDEESSL 394
Q + E +RS + GA +++++E +K+L + + L
Sbjct: 822 VQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQL 881
Query: 395 FKQKAQQKRVFDTVRIANDTRGRSISFPALLPIPGSNRSSVIMTAKPFESGLQQTEDKSL 454
+K + D + ISF V + + F G++ K
Sbjct: 882 LLEKKRDVETLQQTIEEKDQQVTEISF-------SMTEKMVQLNEEKFSLGVEIKTLKEQ 934
Query: 455 LNQGSSSEEV------------AGSSQKMGQPGPSGDSDLATALHRLSLRRQNYLSEKQF 502
LN S +EE +G Q + P+G H L ++
Sbjct: 935 LNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKE------- 987
Query: 503 FAEEWQRKIQ-VLADQKEGVSGCVTPTESLASL 534
E+ +RK+Q L ++KE + E LA+L
Sbjct: 988 -NEQRKRKLQAALINRKELLQRVSRLEEELANL 1019
Score = 33.1 bits (74), Expect = 1.2
Identities = 35/165 (21%), Positives = 72/165 (43%), Gaps = 14/165 (8%)
Query: 137 LKRNHVLSEQNESLEEQLGQAF----DQVNQLQHELCKKDELL-RIVSIASEESETDSSC 191
L+ EQ ++L +Q+ Q +Q++ LQ E+ + ++ ++++ ++ S+ DS
Sbjct: 1080 LEEKLAAEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVA 1139
Query: 192 STPLRFNESFSLSQGLLQLEM-----LQEKLKELEEENMALRSKACHIKTETVTYEEKEQ 246
E+ +S L+EK+ LE+E L+ K T +K Q
Sbjct: 1140 LV----KETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQ 1195
Query: 247 QLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQI 291
+ +EL++ +R+ E+ +S E ++L L Q+
Sbjct: 1196 EKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1240
>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
Length = 1088
Score = 54.7 bits (130), Expect = 4e-07
Identities = 72/295 (24%), Positives = 127/295 (43%), Gaps = 35/295 (11%)
Query: 70 TQSPHQRQHAS---DALSPVLAEETFRYMILGTDRVEQMTKTYNDIDMVTHLLAERDRDL 126
T+ QR HA A L +T M L R+E +T N D L E +
Sbjct: 263 TEENFQRLHAEHERQAKELFLLRKTLEEMEL---RIETQKQTLNARDESIKKLLEMLQSK 319
Query: 127 ELAARIGQALLKRNHVLSEQN---ESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASE 183
L+A+ + +R L+E LE L Q + + L+ E+ ++ E +
Sbjct: 320 GLSAKATEEDHERTRRLAEAEMHVHHLESLLEQKEKENSMLREEMHRRFE-------NAP 372
Query: 184 ESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEE 243
+S + T + +S ++ ++ L++LEEE L+S + TE E
Sbjct: 373 DSAKTKALQTVIEMKDS--------KISSMERGLRDLEEEIQMLKSNGA-LSTEEREEEM 423
Query: 244 KEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVI 303
K+ ++ K ++ ++ ++ +ELS K EL+ Q +L +L +Q D K+H+
Sbjct: 424 KQMEVYRSHSKFMKN---KIGQVKQELSRKDTELLALQTKLETLTNQFSD----SKQHI- 475
Query: 304 EKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLHESQEEIKELRSRSGPTA 358
E LK L A + L E+ L+ R E ML++ ++I+++ G A
Sbjct: 476 --EVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQA 528
Score = 45.8 bits (107), Expect = 2e-04
Identities = 49/201 (24%), Positives = 92/201 (45%), Gaps = 41/201 (20%)
Query: 138 KRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIASEESETDSSCSTPLRF 197
++ +VL ++ E+L+EQL Q++ L+ R+ S+ ++ + TD++ +T
Sbjct: 543 RKVNVLQKKIENLQEQLRDKEKQMSSLKE---------RVKSLQADTTNTDTALTT---- 589
Query: 198 NESFSLSQGLLQLEMLQEKLKELEEENMALRSKACHIKTETVTYEEKEQQLVSDCVKELR 257
L + L + E E+LKE + + E ++Q+ + + K+L+
Sbjct: 590 -----LEEALAEKERTIERLKEQRDRD-----------------EREKQEEIDNYKKDLK 627
Query: 258 ETNAQMSRMTEELSGKSDELIRYQEELSSLLSQIVDLQHKLKEHVI----EKEE-LKLHL 312
+ ++S + +LS K L+ +E SSL S + +LK I +KEE LK+
Sbjct: 628 DLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRLKTLEIALEQKKEECLKMES 687
Query: 313 QASKDAQRQLTMELH-ELQDR 332
Q K + L E+ DR
Sbjct: 688 QLKKAHEAALEARASPEMSDR 708
Score = 42.7 bits (99), Expect = 0.002
Identities = 56/253 (22%), Positives = 103/253 (40%), Gaps = 41/253 (16%)
Query: 126 LELAARIGQALLKRNHVLSEQNESLEEQLGQAFDQVNQLQHELCKKDELLRIVSIA---- 181
L++ R L K+ L EQ E+Q+ ++V LQ + D L + A
Sbjct: 538 LDVKERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEK 597
Query: 182 ----------------SEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELEEENM 225
++ E D+ E SL QG L + L +L+E
Sbjct: 598 ERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKVSLLQG--DLSEKEASLLDLKEHAS 655
Query: 226 ALRSKACHIKTETVTYEEKEQQLVSDCVK---ELRETN--AQMSRMTEELSGKSD----E 276
+L S + T E +Q +C+K +L++ + A +R + E+S + E
Sbjct: 656 SLASSGLKKDSRLKTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLERE 715
Query: 277 LIRYQEELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMEC 336
+ RY++E S +++ L LKE +E E+ D +++ +++D+N +
Sbjct: 716 ITRYKDESSKAQAEVDRLLEILKE--VENEK--------NDKDKKIAELERQVKDQNKKV 765
Query: 337 LGMLHESQEEIKE 349
+ H+ Q E K+
Sbjct: 766 ANLKHKEQVEKKK 778
Score = 41.2 bits (95), Expect = 0.004
Identities = 52/250 (20%), Positives = 108/250 (43%), Gaps = 33/250 (13%)
Query: 113 DMVTHLLAE----RDRDLELAARIGQALLKRNHVLSEQNES------LEEQLGQAFDQVN 162
D + HL E +D + A + + L V +E+N+ LE Q+ +V
Sbjct: 707 DRIQHLEREITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELERQVKDQNKKVA 766
Query: 163 QLQH-ELCKKDELLRIVSIASEESETDSSCSTPLRFNESFSLSQGLLQLEMLQEKLKELE 221
L+H E +K + +++ A + + S L+ + L ++++ELE
Sbjct: 767 NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDS-----------LRKKDDRIEELE 815
Query: 222 EENMALRSKACHIKTETVTYEEKEQQLVSDCVKELRETNAQMSRMTEELSGKSDELIRYQ 281
E ALR ++ I E +E+ ++ K++ E M ++ +EL +L Q
Sbjct: 816 E---ALR-ESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQ 871
Query: 282 EELSSLLSQIVDLQHKLKEHVIEKEELKLHLQASKDAQRQLTMELHELQDRNMECLGMLH 341
+ L+ + + +L+ + ++H+ E E+K + +++ + L EL
Sbjct: 872 QSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSK-------K 924
Query: 342 ESQEEIKELR 351
++QEE+ L+
Sbjct: 925 KTQEEVAALK 934
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,230,812
Number of Sequences: 37866
Number of extensions: 1806903
Number of successful extensions: 12901
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 806
Number of HSP's that attempted gapping in prelim test: 9087
Number of HSP's gapped (non-prelim): 3271
length of query: 914
length of database: 18,247,518
effective HSP length: 111
effective length of query: 803
effective length of database: 14,044,392
effective search space: 11277646776
effective search space used: 11277646776
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.