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Search of human proteins with 188219571
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|188219571 putative homeodomain transcription factor 2
isoform 2 [Homo sapiens]
(747 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|188219571 putative homeodomain transcription factor 2 isoform... 1507 0.0
gi|188219565 putative homeodomain transcription factor 2 isoform... 1507 0.0
gi|188219569 putative homeodomain transcription factor 2 isoform... 1501 0.0
gi|166197666 putative homeodomain transcription factor 1 [Homo s... 777 0.0
gi|188219575 putative homeodomain transcription factor 2 isoform... 687 0.0
gi|188219573 putative homeodomain transcription factor 2 isoform... 681 0.0
gi|60097902 filaggrin [Homo sapiens] 39 0.018
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 38 0.039
gi|161016767 mucin 21 [Homo sapiens] 37 0.051
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 37 0.067
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 37 0.067
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 37 0.067
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 37 0.067
gi|150418009 transforming, acidic coiled-coil containing protein... 36 0.11
gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens] 35 0.19
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 35 0.19
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 35 0.19
gi|70610136 poly (ADP-ribose) glycohydrolase [Homo sapiens] 35 0.25
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s... 34 0.57
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ... 33 0.74
gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens] 33 1.3
gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] 33 1.3
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] 33 1.3
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ... 32 2.2
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 32 2.2
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 32 2.2
gi|62241003 cardiomyopathy associated 5 [Homo sapiens] 32 2.8
gi|109637791 transcription factor-like nuclear regulator [Homo s... 32 2.8
gi|222831577 zinc finger protein 286B [Homo sapiens] 31 3.7
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 31 3.7
>gi|188219571 putative homeodomain transcription factor 2 isoform 2
[Homo sapiens]
Length = 747
Score = 1507 bits (3902), Expect = 0.0
Identities = 747/747 (100%), Positives = 747/747 (100%)
Query: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA
Sbjct: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
Query: 61 FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST
Sbjct: 61 FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
Query: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG
Sbjct: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
Query: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV
Sbjct: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
Query: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300
SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE
Sbjct: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300
Query: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP 360
GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP
Sbjct: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP 360
Query: 361 ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG 420
ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG
Sbjct: 361 ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG 420
Query: 421 LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR 480
LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR
Sbjct: 421 LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR 480
Query: 481 LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY 540
LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY
Sbjct: 481 LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY 540
Query: 541 KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS 600
KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS
Sbjct: 541 KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS 600
Query: 601 AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT 660
AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT
Sbjct: 601 AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT 660
Query: 661 SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT 720
SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT
Sbjct: 661 SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT 720
Query: 721 QVVILSAVSGVISDLLGFNLKLWKIKS 747
QVVILSAVSGVISDLLGFNLKLWKIKS
Sbjct: 721 QVVILSAVSGVISDLLGFNLKLWKIKS 747
>gi|188219565 putative homeodomain transcription factor 2 isoform 2
[Homo sapiens]
Length = 747
Score = 1507 bits (3902), Expect = 0.0
Identities = 747/747 (100%), Positives = 747/747 (100%)
Query: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA
Sbjct: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
Query: 61 FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST
Sbjct: 61 FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
Query: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG
Sbjct: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
Query: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV
Sbjct: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
Query: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300
SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE
Sbjct: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300
Query: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP 360
GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP
Sbjct: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP 360
Query: 361 ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG 420
ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG
Sbjct: 361 ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG 420
Query: 421 LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR 480
LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR
Sbjct: 421 LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR 480
Query: 481 LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY 540
LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY
Sbjct: 481 LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY 540
Query: 541 KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS 600
KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS
Sbjct: 541 KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS 600
Query: 601 AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT 660
AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT
Sbjct: 601 AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT 660
Query: 661 SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT 720
SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT
Sbjct: 661 SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT 720
Query: 721 QVVILSAVSGVISDLLGFNLKLWKIKS 747
QVVILSAVSGVISDLLGFNLKLWKIKS
Sbjct: 721 QVVILSAVSGVISDLLGFNLKLWKIKS 747
>gi|188219569 putative homeodomain transcription factor 2 isoform 1
[Homo sapiens]
Length = 751
Score = 1501 bits (3887), Expect = 0.0
Identities = 747/751 (99%), Positives = 747/751 (99%), Gaps = 4/751 (0%)
Query: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIK----GLRNKPKKTAHVKPDLIDVDLV 56
MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIK GLRNKPKKTAHVKPDLIDVDLV
Sbjct: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLV 60
Query: 57 RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL 116
RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL
Sbjct: 61 RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL 120
Query: 117 FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV 176
FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV
Sbjct: 121 FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV 180
Query: 177 HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD 236
HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD
Sbjct: 181 HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD 240
Query: 237 NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV 296
NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV
Sbjct: 241 NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV 300
Query: 297 SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSE 356
SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSE
Sbjct: 301 SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSE 360
Query: 357 SARPESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHS 416
SARPESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHS
Sbjct: 361 SARPESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHS 420
Query: 417 SHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTP 476
SHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTP
Sbjct: 421 SHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTP 480
Query: 477 FVFRLSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVA 536
FVFRLSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVA
Sbjct: 481 FVFRLSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVA 540
Query: 537 ERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDV 596
ERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDV
Sbjct: 541 ERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDV 600
Query: 597 IVSSAFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKK 656
IVSSAFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKK
Sbjct: 601 IVSSAFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKK 660
Query: 657 YSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLL 716
YSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLL
Sbjct: 661 YSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLL 720
Query: 717 YNITQVVILSAVSGVISDLLGFNLKLWKIKS 747
YNITQVVILSAVSGVISDLLGFNLKLWKIKS
Sbjct: 721 YNITQVVILSAVSGVISDLLGFNLKLWKIKS 751
>gi|166197666 putative homeodomain transcription factor 1 [Homo
sapiens]
Length = 762
Score = 777 bits (2006), Expect = 0.0
Identities = 431/796 (54%), Positives = 535/796 (67%), Gaps = 83/796 (10%)
Query: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
MAS DAI WYQKKIGAYDQQIWEKS+EQ +IKGL+NKPKK H+KPDLIDVDL+RGS
Sbjct: 1 MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGLKNKPKKMGHIKPDLIDVDLIRGST 60
Query: 61 FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
FAKAKPE PWTSLTRKG+VRVVFFP F WW+QVTS IF WLL+LY +QV AIVL+
Sbjct: 61 FAKAKPEIPWTSLTRKGLVRVVFFPLFSNWWIQVTSLRIFVWLLLLYFMQVIAIVLYLMM 120
Query: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
+ ++EV+GP+ LMLL+GTVHCQIVST+ +P + G +RRRKLRK + G
Sbjct: 121 P---IVNISEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVN------G 171
Query: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
DGS N V+ G T SV + W F + K+ K +K TETDN
Sbjct: 172 DGSRENGNNSSDKVR--GIETLESV-PIIGGFWE-TIFGNRIKRVKLISNKGTETDN--- 224
Query: 241 SLDGKKTVKSGEDGIQNHEPQC-------ETIRPEETAWNT---GTLRNGPS--KDTQRT 288
+P C RPE W T +G ++ R
Sbjct: 225 ------------------DPSCVHPIIKRRQCRPEIRMWQTREKAKFSDGEKCRREAFRR 266
Query: 289 ITN-VSDEVSSEEGPETGYS---LRRHVDRTSEG---VLRNRK---SHHYKKHYPN---- 334
+ N VSD++SSEE E LRR V+ S ++NRK S H
Sbjct: 267 LGNGVSDDLSSEEDGEARTQMILLRRSVEGASSDNGCEVKNRKSILSRHLNSQVKKTTTR 326
Query: 335 ---------------------EDAPKSGTSCSSR-CSSSRQDSESARPESETEDVLWEDL 372
+SG S SR + SR+DSES R +SETED+LW+DL
Sbjct: 327 WCHIVRDSDSLAESEFESAAFSQGSRSGVSGGSRSLNMSRRDSESTRHDSETEDMLWDDL 386
Query: 373 LHCAECHSSCTSETD-VENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEG 431
LH EC SS TS+++ + ++ K++ ++D F Q+HL WL +S P +++SAI+WEG
Sbjct: 387 LHGPECRSSVTSDSEGAHVNTLHSGTKRDPKEDVFQQNHLFWLQNSSPSSDRVSAIIWEG 446
Query: 432 NDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLT 491
N+CKK DMSVLEISG+IM+RVN++ G+GYQ+ GN V++ L PF+ RL + L+QL
Sbjct: 447 NECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNVVTIGLAFFPFLHRLFREKSLDQLK 506
Query: 492 AHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFG 551
+ SA E+ + G+ ++ + II+F R+ L W+FFF++CVAERTYKQR LFAKLF
Sbjct: 507 SISAEEILTLFCGAPPVTPIIVLSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFS 566
Query: 552 HLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFI 611
H+TSAR+ARK E+PHFRLKKV+NIK+WLSLRSYLKRRGPQRSVDV+VSS FLLT+S+ FI
Sbjct: 567 HITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFI 626
Query: 612 CCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLY 671
CCAQ+L H+ FL+ YNWE +IW +L LFLLR +LGSET+KKYSN SILLTEQINLY
Sbjct: 627 CCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLY 686
Query: 672 LKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGV 731
LKMEKKPNKKE+LTLVNNVLKL+TKLLKELD+PFRLYGLTMNPL+YNIT+VVILSAVSGV
Sbjct: 687 LKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGV 746
Query: 732 ISDLLGFNLKLWKIKS 747
ISDLLGFN++LWKIKS
Sbjct: 747 ISDLLGFNIRLWKIKS 762
>gi|188219575 putative homeodomain transcription factor 2 isoform 4
[Homo sapiens]
Length = 352
Score = 687 bits (1773), Expect = 0.0
Identities = 335/335 (100%), Positives = 335/335 (100%)
Query: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA
Sbjct: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
Query: 61 FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST
Sbjct: 61 FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
Query: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG
Sbjct: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
Query: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV
Sbjct: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
Query: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300
SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE
Sbjct: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300
Query: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE 335
GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE
Sbjct: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE 335
>gi|188219573 putative homeodomain transcription factor 2 isoform 3
[Homo sapiens]
Length = 356
Score = 681 bits (1758), Expect = 0.0
Identities = 335/339 (98%), Positives = 335/339 (98%), Gaps = 4/339 (1%)
Query: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIK----GLRNKPKKTAHVKPDLIDVDLV 56
MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIK GLRNKPKKTAHVKPDLIDVDLV
Sbjct: 1 MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLV 60
Query: 57 RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL 116
RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL
Sbjct: 61 RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL 120
Query: 117 FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV 176
FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV
Sbjct: 121 FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV 180
Query: 177 HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD 236
HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD
Sbjct: 181 HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD 240
Query: 237 NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV 296
NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV
Sbjct: 241 NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV 300
Query: 297 SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE 335
SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE
Sbjct: 301 SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE 339
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 38.9 bits (89), Expect = 0.018
Identities = 67/275 (24%), Positives = 104/275 (37%), Gaps = 40/275 (14%)
Query: 159 STGGK---RRRKLRKAAHLEVHREGDGS----------STTDNTQEGAVQNHGTSTSHSV 205
STGG+ R + R ++ +EG + + E +V G S SH
Sbjct: 3730 STGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHS 3789
Query: 206 GTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETI 265
T + A+ SGS+ A S ET N S DG S G ++HE +
Sbjct: 3790 HTTSQGRSDASHGQSGSRSA------SRETRNEEQSGDG-----SRHSGSRHHEASTQAD 3838
Query: 266 RPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRNRKS 325
+ +G + S+ ++R ++VS + SE PE +R SE RN
Sbjct: 3839 SSRHS--QSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDS-------ERRSESASRN--- 3886
Query: 326 HHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESET--EDVLWEDLLHCAECHSSCT 383
HH + D + S S R ++S S + +S T E + L + HS
Sbjct: 3887 HHGSSREQSRDGSRHPGS-SHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQ 3945
Query: 384 SETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSH 418
S + + + E + QS L W H S+
Sbjct: 3946 SRGSPHSSS-SYHYQSEGTERQKGQSGLVWRHGSY 3979
Score = 33.9 bits (76), Expect = 0.57
Identities = 57/231 (24%), Positives = 93/231 (40%), Gaps = 40/231 (17%)
Query: 159 STGGKR---RRKLRKAAHLEVHREGD-------GSST---TDNTQEGAVQNHGTSTSHSV 205
STGG++ + R ++ +EG GSS + E +V G S SH
Sbjct: 488 STGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHS 547
Query: 206 GTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETI 265
T + A+ SGS+ A S +T N S DG + G ++HE +
Sbjct: 548 HTTSQGRSDASHGQSGSRSA------SRQTRNEEQSGDGTR-----HSGSRHHEASSQAD 596
Query: 266 RPEETAWNTGTLRNGP--SKDTQRTITNVSDEVSSEEGPE--TGYSLRRH---VDRTSEG 318
+ G +GP S++ +++ SD E E +G + R H S
Sbjct: 597 SSRHSQVGQGQ-SSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRD 655
Query: 319 VLRNRKSHHYKK---HYPNEDAPKSGT-----SCSSRCSSSRQDSESARPE 361
R+ +SHH + + + + KSGT S S + +SS + + S+ E
Sbjct: 656 GSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGE 706
Score = 30.4 bits (67), Expect = 6.3
Identities = 38/170 (22%), Positives = 62/170 (36%), Gaps = 16/170 (9%)
Query: 191 EGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKS 250
E +V G S SH T + A+ SGS+ A K ++ +G S
Sbjct: 1182 EQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDG-----------S 1230
Query: 251 GEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRR 310
G ++HE + G ++ S+ ++ ++VS + SE + L
Sbjct: 1231 RHSGSRHHEAASWADSSRHS--QVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSG 1288
Query: 311 HVDRTSEGVLRNRKSHHYKKH--YPNEDAPKSGTSCSSRCSSSRQDSESA 358
R G R +S +H + ED G S S S +ES+
Sbjct: 1289 SASRNHHGSSR-EQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESS 1337
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 37.7 bits (86), Expect = 0.039
Identities = 36/148 (24%), Positives = 64/148 (43%), Gaps = 29/148 (19%)
Query: 218 FLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTL 277
F S S++ ++S D S+++++ S G++ +SGE+G N +
Sbjct: 675 FYSESEEEEDSSDSSSDSESESGSESGEQG-ESGEEGDSNEDS----------------- 716
Query: 278 RNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDA 337
S+D+ S E SE G E+G +R R S+ ++ K++ ++ +
Sbjct: 717 ----SEDS-------SSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTS 765
Query: 338 PKSGTSCSSRCSSSRQDSESARPESETE 365
S SS SS + PESE+E
Sbjct: 766 DSSNDESSSIEDSSSDSESESEPESESE 793
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 37.4 bits (85), Expect = 0.051
Identities = 42/180 (23%), Positives = 65/180 (36%), Gaps = 9/180 (5%)
Query: 183 SSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSL 242
S TT N A + ++TS T ++ SG+ A NS +T + G +
Sbjct: 215 SRTTSNGAGTATNSESSTTSSGASTATNS--ESSTPSSGAGTATNSESSTTSSGAGTATN 272
Query: 243 DGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGP 302
TV SG + N E + + NT T + + SD ++ G
Sbjct: 273 SESSTVSSGISTVTNSESSTPS-----SGANTATNSESSTTSSGANTATNSDSSTTSSGA 327
Query: 303 ETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPES 362
T + TS G S A SG+S +S +S+ +SES+ S
Sbjct: 328 ST--ATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSS 385
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 37.0 bits (84), Expect = 0.067
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 26/193 (13%)
Query: 222 SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGP 281
S + +++I T + Y +++ ++KS + +N C+ ++ A + G
Sbjct: 555 SLRKRDTITDKTARTSSYKAMEAASSLKS-QAATKNLSDACKPLKKRNRASTAASSALGF 613
Query: 282 SKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRT-SEGVLRNRKSHH---YKKHYPNEDA 337
SK + + + +EVS G E S D T +E + ++KS KK Y +
Sbjct: 614 SKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLC 673
Query: 338 PKSGT--SCSSRCSSSRQDS---ESARPESETEDVLWEDLLHCAECHS---SC----TSE 385
K G+ C C + + S RPE C+EC S SC S+
Sbjct: 674 EKPGSLLLCEGPCCGAFHLACLGLSRRPEGR---------FTCSECASGIHSCFVCKESK 724
Query: 386 TDVENHQINPCVK 398
TDV+ + C K
Sbjct: 725 TDVKRCVVTQCGK 737
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 37.0 bits (84), Expect = 0.067
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 26/193 (13%)
Query: 222 SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGP 281
S + +++I T + Y +++ ++KS + +N C+ ++ A + G
Sbjct: 555 SLRKRDTITDKTARTSSYKAMEAASSLKS-QAATKNLSDACKPLKKRNRASTAASSALGF 613
Query: 282 SKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRT-SEGVLRNRKSHH---YKKHYPNEDA 337
SK + + + +EVS G E S D T +E + ++KS KK Y +
Sbjct: 614 SKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLC 673
Query: 338 PKSGT--SCSSRCSSSRQDS---ESARPESETEDVLWEDLLHCAECHS---SC----TSE 385
K G+ C C + + S RPE C+EC S SC S+
Sbjct: 674 EKPGSLLLCEGPCCGAFHLACLGLSRRPEGR---------FTCSECASGIHSCFVCKESK 724
Query: 386 TDVENHQINPCVK 398
TDV+ + C K
Sbjct: 725 TDVKRCVVTQCGK 737
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 37.0 bits (84), Expect = 0.067
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 26/193 (13%)
Query: 222 SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGP 281
S + +++I T + Y +++ ++KS + +N C+ ++ A + G
Sbjct: 555 SLRKRDTITDKTARTSSYKAMEAASSLKS-QAATKNLSDACKPLKKRNRASTAASSALGF 613
Query: 282 SKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRT-SEGVLRNRKSHH---YKKHYPNEDA 337
SK + + + +EVS G E S D T +E + ++KS KK Y +
Sbjct: 614 SKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLC 673
Query: 338 PKSGT--SCSSRCSSSRQDS---ESARPESETEDVLWEDLLHCAECHS---SC----TSE 385
K G+ C C + + S RPE C+EC S SC S+
Sbjct: 674 EKPGSLLLCEGPCCGAFHLACLGLSRRPEGR---------FTCSECASGIHSCFVCKESK 724
Query: 386 TDVENHQINPCVK 398
TDV+ + C K
Sbjct: 725 TDVKRCVVTQCGK 737
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 37.0 bits (84), Expect = 0.067
Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 26/193 (13%)
Query: 222 SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGP 281
S + +++I T + Y +++ ++KS + +N C+ ++ A + G
Sbjct: 555 SLRKRDTITDKTARTSSYKAMEAASSLKS-QAATKNLSDACKPLKKRNRASTAASSALGF 613
Query: 282 SKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRT-SEGVLRNRKSHH---YKKHYPNEDA 337
SK + + + +EVS G E S D T +E + ++KS KK Y +
Sbjct: 614 SKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLC 673
Query: 338 PKSGT--SCSSRCSSSRQDS---ESARPESETEDVLWEDLLHCAECHS---SC----TSE 385
K G+ C C + + S RPE C+EC S SC S+
Sbjct: 674 EKPGSLLLCEGPCCGAFHLACLGLSRRPEGR---------FTCSECASGIHSCFVCKESK 724
Query: 386 TDVENHQINPCVK 398
TDV+ + C K
Sbjct: 725 TDVKRCVVTQCGK 737
>gi|150418009 transforming, acidic coiled-coil containing protein 2
isoform a [Homo sapiens]
Length = 2948
Score = 36.2 bits (82), Expect = 0.11
Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 8/70 (11%)
Query: 243 DGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPS-------KDTQRTITNV-SD 294
DGK V S + + H+P+ + + PEE + + R GPS KD R + V SD
Sbjct: 1789 DGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSD 1848
Query: 295 EVSSEEGPET 304
E EG E+
Sbjct: 1849 ETRGAEGTES 1858
>gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]
Length = 851
Score = 35.4 bits (80), Expect = 0.19
Identities = 36/166 (21%), Positives = 58/166 (34%), Gaps = 6/166 (3%)
Query: 201 TSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEP 260
T H VG A+ G + ++ + ++ T++G DG + E G+ E
Sbjct: 62 TEHDVGQEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVNQEDGPEDASPTEHGVDQQED 121
Query: 261 QCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVL 320
E RP E + +GP +D T V + E+GPE +D+ +G
Sbjct: 122 GPEDARPTEHGIDQE--EDGP-EDASLTEHGVDQQ---EDGPEDASPTEHGIDQEEDGPE 175
Query: 321 RNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETED 366
+ H ED P+ + E A P D
Sbjct: 176 DASPTEHEHGVDQEEDGPEDASPTEHGVDQEEDGPEDASPTEHGVD 221
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 35.4 bits (80), Expect = 0.19
Identities = 50/230 (21%), Positives = 85/230 (36%), Gaps = 17/230 (7%)
Query: 151 TRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQN---HGTSTSHSVGT 207
T + K + K+R LR + ++ D +S++ + E QN G+S +
Sbjct: 1134 TSSKKKAVIVKEKKRNSLRTSTK---RKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP 1190
Query: 208 VFRDLW---HAAFFLSG-----SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHE 259
V +L H F S SK ++D + ++ + K ++ + + + E
Sbjct: 1191 VTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDE 1250
Query: 260 PQCETIRPEETAWNTGTLRN-GPSKDTQRTITNVSDEVSSEEG--PETGYSLRRHVDRTS 316
PEE TG P + + N + SEE P + L RH S
Sbjct: 1251 DGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVS 1310
Query: 317 EGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETED 366
+G K K+H + + S S Q+S + SE+ED
Sbjct: 1311 DGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1360
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 35.4 bits (80), Expect = 0.19
Identities = 50/230 (21%), Positives = 85/230 (36%), Gaps = 17/230 (7%)
Query: 151 TRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQN---HGTSTSHSVGT 207
T + K + K+R LR + ++ D +S++ + E QN G+S +
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTK---RKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP 1228
Query: 208 VFRDLW---HAAFFLSG-----SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHE 259
V +L H F S SK ++D + ++ + K ++ + + + E
Sbjct: 1229 VTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDE 1288
Query: 260 PQCETIRPEETAWNTGTLRN-GPSKDTQRTITNVSDEVSSEEG--PETGYSLRRHVDRTS 316
PEE TG P + + N + SEE P + L RH S
Sbjct: 1289 DGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVS 1348
Query: 317 EGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETED 366
+G K K+H + + S S Q+S + SE+ED
Sbjct: 1349 DGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1398
>gi|70610136 poly (ADP-ribose) glycohydrolase [Homo sapiens]
Length = 976
Score = 35.0 bits (79), Expect = 0.25
Identities = 51/209 (24%), Positives = 79/209 (37%), Gaps = 42/209 (20%)
Query: 182 GSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKN----SIDKS-TETD 236
G T ++ + +N+ T + +V +D F+ +K +N S+DKS TE
Sbjct: 87 GIKTAESESLDSKENNNTRIESMMSSVQKD----NFYQHNVEKLENVSQLSLDKSPTEKS 142
Query: 237 NGYVSL-----------DGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDT 285
Y++ +GK T + + EPQ T+ PE+ ++ + P D
Sbjct: 143 TQYLNQHQTAAMCKWQNEGKHT-----EQLLESEPQTVTLVPEQ--FSNANIDRSPQNDD 195
Query: 286 QRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHY--KKHYPNEDAPKSGTS 343
S+E + T L T + R KSH K P ED
Sbjct: 196 HSDTD--SEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGED------- 246
Query: 344 CSSRCSSSRQDSESARPESETEDVLWEDL 372
C+S +QD PES DV ED+
Sbjct: 247 ----CASCQQDEIDVVPESPLSDVGSEDV 271
>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
sapiens]
Length = 908
Score = 33.9 bits (76), Expect = 0.57
Identities = 30/117 (25%), Positives = 46/117 (39%), Gaps = 21/117 (17%)
Query: 308 LRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDV 367
LR H+ T + ++ + N+ +P S +S SS S DS+S +S +E
Sbjct: 643 LREHLKNTPKVIVAQKPDVEQ-----NKSSPSSSSSASSSSESDSSDSDSDSSDSSSESS 697
Query: 368 LWEDLLHCAECHSSCTS--------------ETD--VENHQINPCVKKEYRDDPFHQ 408
E HSS ++ E D + N Q N +KE R + HQ
Sbjct: 698 SEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQ 754
>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
[Homo sapiens]
Length = 2649
Score = 33.5 bits (75), Expect = 0.74
Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 10/71 (14%)
Query: 373 LHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLH-SSHPGLEKISA----- 426
L+C C +C S+ ENH C E+ LPW H S PGL K
Sbjct: 40 LYCPACLVTCHSQEAFENH----CASSEHAQMVAFDQALPWEHRSPPPGLSKFELCPKPD 95
Query: 427 IVWEGNDCKKA 437
+ G+ C KA
Sbjct: 96 LCEYGDACTKA 106
>gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens]
Length = 1070
Score = 32.7 bits (73), Expect = 1.3
Identities = 36/166 (21%), Positives = 58/166 (34%), Gaps = 8/166 (4%)
Query: 201 TSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEP 260
T H VG A+ G + ++ + ++ T++G DG + E G+ E
Sbjct: 283 TEHDVGQEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVNQEDGPEDASPTEHGVDQQED 342
Query: 261 QCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVL 320
E RP E + +GP +D T V + E+GPE +D+ +G
Sbjct: 343 GPEDARPTEHGIDQE--EDGP-EDASLTEHGVDQQ---EDGPEDASPTEHGIDQEEDGPE 396
Query: 321 RNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETED 366
+ H ED P+ + E A P D
Sbjct: 397 DASPTEHGVDQ--EEDGPEDASPTEHGVDQEEDGPEDASPTEHGVD 440
>gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]
Length = 1090
Score = 32.7 bits (73), Expect = 1.3
Identities = 39/181 (21%), Positives = 71/181 (39%), Gaps = 29/181 (16%)
Query: 203 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 262
HS V R+ W +G+ + + + + +E D + VK ED IQ E +
Sbjct: 40 HSKSKVLREKWLLQGIPAGTAEEEEARRRQSEED--------EFRVKQLEDNIQRLEQEI 91
Query: 263 ETIRPEETAWNTGT-LRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLR 321
+T+ EE+ + + K+T+++ + SS +G Y + D +L
Sbjct: 92 QTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQLPDLP---ILC 148
Query: 322 NRKSHHYKKHYPNEDAP-------------KSGTSCSSRCSSSRQDSESARPESETEDVL 368
+R + + P +D K G S S+ +S D +P +ED +
Sbjct: 149 SRTA----EPSPGQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQLSEDDI 204
Query: 369 W 369
W
Sbjct: 205 W 205
>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
Length = 1103
Score = 32.7 bits (73), Expect = 1.3
Identities = 39/181 (21%), Positives = 71/181 (39%), Gaps = 29/181 (16%)
Query: 203 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 262
HS V R+ W +G+ + + + + +E D + VK ED IQ E +
Sbjct: 40 HSKSKVLREKWLLQGIPAGTAEEEEARRRQSEED--------EFRVKQLEDNIQRLEQEI 91
Query: 263 ETIRPEETAWNTGT-LRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLR 321
+T+ EE+ + + K+T+++ + SS +G Y + D +L
Sbjct: 92 QTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQLPDLP---ILC 148
Query: 322 NRKSHHYKKHYPNEDAP-------------KSGTSCSSRCSSSRQDSESARPESETEDVL 368
+R + + P +D K G S S+ +S D +P +ED +
Sbjct: 149 SRTA----EPSPGQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQLSEDDI 204
Query: 369 W 369
W
Sbjct: 205 W 205
>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
sapiens]
Length = 1723
Score = 32.0 bits (71), Expect = 2.2
Identities = 42/199 (21%), Positives = 76/199 (38%), Gaps = 23/199 (11%)
Query: 180 GDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAF------FLSGSKKAKNSIDKST 233
G G T + + Q+ G + SVG+ W AA +SG + N+ +
Sbjct: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGS-----WGAARGPSGTDTVSGQSNSGNNGNNGK 451
Query: 234 ETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSK--DTQRTITN 291
E ++ + +K+ S D N+ R +WN G + +K + + +
Sbjct: 452 EREDSWKGASVQKSTGSKNDSWDNNN------RSTGGSWNFGPQDSNDNKWGEGNKMTSG 505
Query: 292 VSD----EVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSR 347
VS + + + + G + +S G N+K H ++ N AP G S SS
Sbjct: 506 VSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSST 565
Query: 348 CSSSRQDSESARPESETED 366
S S + ++ + D
Sbjct: 566 GSEVGGQSTGSNHKAGSSD 584
>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
sapiens]
Length = 1833
Score = 32.0 bits (71), Expect = 2.2
Identities = 42/199 (21%), Positives = 76/199 (38%), Gaps = 23/199 (11%)
Query: 180 GDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAF------FLSGSKKAKNSIDKST 233
G G T + + Q+ G + SVG+ W AA +SG + N+ +
Sbjct: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGS-----WGAARGPSGTDTVSGQSNSGNNGNNGK 451
Query: 234 ETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSK--DTQRTITN 291
E ++ + +K+ S D N+ R +WN G + +K + + +
Sbjct: 452 EREDSWKGASVQKSTGSKNDSWDNNN------RSTGGSWNFGPQDSNDNKWGEGNKMTSG 505
Query: 292 VSD----EVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSR 347
VS + + + + G + +S G N+K H ++ N AP G S SS
Sbjct: 506 VSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSST 565
Query: 348 CSSSRQDSESARPESETED 366
S S + ++ + D
Sbjct: 566 GSEVGGQSTGSNHKAGSSD 584
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 32.0 bits (71), Expect = 2.2
Identities = 51/227 (22%), Positives = 85/227 (37%), Gaps = 32/227 (14%)
Query: 229 IDKSTET--DNGYVSLDGKKTVKSGEDGIQNHEPQCETIR-PEETAWNTGTLR------- 278
I+++T++ D+GY KT K+ EDG ++E +T R PEE ++
Sbjct: 1909 IERTTKSPSDSGYSYETIGKTTKTPEDGDYSYEIIEKTTRTPEEGGYSYDISEKTTSPPE 1968
Query: 279 -NGPSKDTQRTITNVSDEVS-----SEEGPET----GYSLRRHVDRTSEGVLRNRKSHHY 328
+G S + + D++S SE+G T YS TS + + Y
Sbjct: 1969 VSGYSYEKTERSRRLLDDISNGYDDSEDGGHTLGDPSYSYETTEKITS---FPESEGYSY 2025
Query: 329 KKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSCTSETDV 388
+ P + T C + + P++ T DL + AE S + DV
Sbjct: 2026 ETSTKTTRTPDTSTYCYETA-----EKITRTPQASTYSYETSDLCYTAEKKSPSEARQDV 2080
Query: 389 ENHQINPC----VKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEG 431
+ ++ C K E + + L W S P E + G
Sbjct: 2081 DLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEPTEESEKPLTQSG 2127
>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
Length = 4069
Score = 31.6 bits (70), Expect = 2.8
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 9/77 (11%)
Query: 234 ETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGT-------LRNG-PSKDT 285
E +N +S +G ++ + +H + E + E W G+ ++ G PSK++
Sbjct: 2733 EIENHSLSQEGNLVLEKSSRDMPDHSEEKEQFKESEL-WKGGSVDITKESMKEGFPSKES 2791
Query: 286 QRTITNVSDEVSSEEGP 302
+RT+ DE S E P
Sbjct: 2792 ERTLARPFDETKSSETP 2808
>gi|109637791 transcription factor-like nuclear regulator [Homo
sapiens]
Length = 2624
Score = 31.6 bits (70), Expect = 2.8
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Query: 149 VSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGS-STTDNTQEGAVQNHGTSTSHSVGT 207
V + K ST ++ K++K A V+ + D S S+ + E + ++ T S+
Sbjct: 386 VKNHSLKEKKSTKPRKNVKVKKVACEGVNNDPDESMSSRISDTERSQKDAQTVEEESLTL 445
Query: 208 VFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRP 267
D A + ++K + + + G +L TV++G + H+ +C+ IRP
Sbjct: 446 SREDAEQVALEVDLNQKKRRRKKQDGANELGVNNLLENATVQAGPSKGEKHKNKCQAIRP 505
Query: 268 E 268
E
Sbjct: 506 E 506
>gi|222831577 zinc finger protein 286B [Homo sapiens]
Length = 522
Score = 31.2 bits (69), Expect = 3.7
Identities = 21/102 (20%), Positives = 46/102 (45%), Gaps = 15/102 (14%)
Query: 316 SEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSR--------QDSESARPESETEDV 367
S +++++++H +K Y ++ K+ + CSS R + SE + S++ +
Sbjct: 367 SSALIKHQRTHTGEKPYKCQECGKAFSHCSSLTKHQRVHTGEKPYECSECGKTFSQSTHL 426
Query: 368 LWEDLLH-------CAECHSSCTSETDVENHQINPCVKKEYR 402
+ +H C+EC + + ++ HQ KK Y+
Sbjct: 427 VQHQRIHTGEKPYECSECGKTFSQSSNFAKHQRIHIGKKPYK 468
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 31.2 bits (69), Expect = 3.7
Identities = 36/152 (23%), Positives = 61/152 (40%), Gaps = 12/152 (7%)
Query: 268 EETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEG-PETGYSLRRHVDRTSEG-VLRNRKS 325
EE A + P K+ + E SEEG P+ G+ + EG +R +
Sbjct: 441 EEGASENNAKESSPEKEAEEGCP----EKESEEGCPKRGFEGSCSQKESEEGNPVRGSEE 496
Query: 326 HHYKKHYPNE----DAPKSGTSCSSRCSSSRQDSESARP--ESETEDVLWEDLLHCAECH 379
KK + D ++G + S +++ E P ESE +D E C+E
Sbjct: 497 DSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQ 556
Query: 380 SSCTSETDVENHQINPCVKKEYRDDPFHQSHL 411
S SE + E + + + +E + H++ L
Sbjct: 557 SEDGSEREFEENGLEKDLDEEGSEKELHENVL 588
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,761,470
Number of Sequences: 37866
Number of extensions: 1241463
Number of successful extensions: 4541
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 4482
Number of HSP's gapped (non-prelim): 88
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.