Guide to the Human Genome
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Search of human proteins with 188219565

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|188219565 putative homeodomain transcription factor 2
isoform 2 [Homo sapiens]
         (747 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|188219571 putative homeodomain transcription factor 2 isoform...  1507   0.0  
gi|188219565 putative homeodomain transcription factor 2 isoform...  1507   0.0  
gi|188219569 putative homeodomain transcription factor 2 isoform...  1501   0.0  
gi|166197666 putative homeodomain transcription factor 1 [Homo s...   777   0.0  
gi|188219575 putative homeodomain transcription factor 2 isoform...   687   0.0  
gi|188219573 putative homeodomain transcription factor 2 isoform...   681   0.0  
gi|60097902 filaggrin [Homo sapiens]                                   39   0.018
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H...    38   0.039
gi|161016767 mucin 21 [Homo sapiens]                                   37   0.051
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    37   0.067
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    37   0.067
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform...    37   0.067
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor...    37   0.067
gi|150418009 transforming, acidic coiled-coil containing protein...    36   0.11 
gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]           35   0.19 
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    35   0.19 
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    35   0.19 
gi|70610136 poly (ADP-ribose) glycohydrolase [Homo sapiens]            35   0.25 
gi|55749769 CWC22 spliceosome-associated protein homolog [Homo s...    34   0.57 
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ...    33   0.74 
gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens]           33   1.3  
gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]               33   1.3  
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]                33   1.3  
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ...    32   2.2  
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ...    32   2.2  
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          32   2.2  
gi|62241003 cardiomyopathy associated 5 [Homo sapiens]                 32   2.8  
gi|109637791 transcription factor-like nuclear regulator [Homo s...    32   2.8  
gi|222831577 zinc finger protein 286B [Homo sapiens]                   31   3.7  
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]                31   3.7  

>gi|188219571 putative homeodomain transcription factor 2 isoform 2
           [Homo sapiens]
          Length = 747

 Score = 1507 bits (3902), Expect = 0.0
 Identities = 747/747 (100%), Positives = 747/747 (100%)

Query: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
           MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA
Sbjct: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60

Query: 61  FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
           FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST
Sbjct: 61  FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120

Query: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
           SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG
Sbjct: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180

Query: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
           DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV
Sbjct: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240

Query: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300
           SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE
Sbjct: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300

Query: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP 360
           GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP
Sbjct: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP 360

Query: 361 ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG 420
           ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG
Sbjct: 361 ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG 420

Query: 421 LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR 480
           LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR
Sbjct: 421 LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR 480

Query: 481 LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY 540
           LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY
Sbjct: 481 LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY 540

Query: 541 KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS 600
           KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS
Sbjct: 541 KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS 600

Query: 601 AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT 660
           AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT
Sbjct: 601 AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT 660

Query: 661 SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT 720
           SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT
Sbjct: 661 SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT 720

Query: 721 QVVILSAVSGVISDLLGFNLKLWKIKS 747
           QVVILSAVSGVISDLLGFNLKLWKIKS
Sbjct: 721 QVVILSAVSGVISDLLGFNLKLWKIKS 747


>gi|188219565 putative homeodomain transcription factor 2 isoform 2
           [Homo sapiens]
          Length = 747

 Score = 1507 bits (3902), Expect = 0.0
 Identities = 747/747 (100%), Positives = 747/747 (100%)

Query: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
           MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA
Sbjct: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60

Query: 61  FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
           FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST
Sbjct: 61  FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120

Query: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
           SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG
Sbjct: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180

Query: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
           DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV
Sbjct: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240

Query: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300
           SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE
Sbjct: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300

Query: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP 360
           GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP
Sbjct: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARP 360

Query: 361 ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG 420
           ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG
Sbjct: 361 ESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSHPG 420

Query: 421 LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR 480
           LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR
Sbjct: 421 LEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFR 480

Query: 481 LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY 540
           LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY
Sbjct: 481 LSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTY 540

Query: 541 KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS 600
           KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS
Sbjct: 541 KQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSS 600

Query: 601 AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT 660
           AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT
Sbjct: 601 AFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNT 660

Query: 661 SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT 720
           SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT
Sbjct: 661 SILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNIT 720

Query: 721 QVVILSAVSGVISDLLGFNLKLWKIKS 747
           QVVILSAVSGVISDLLGFNLKLWKIKS
Sbjct: 721 QVVILSAVSGVISDLLGFNLKLWKIKS 747


>gi|188219569 putative homeodomain transcription factor 2 isoform 1
           [Homo sapiens]
          Length = 751

 Score = 1501 bits (3887), Expect = 0.0
 Identities = 747/751 (99%), Positives = 747/751 (99%), Gaps = 4/751 (0%)

Query: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIK----GLRNKPKKTAHVKPDLIDVDLV 56
           MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIK    GLRNKPKKTAHVKPDLIDVDLV
Sbjct: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLV 60

Query: 57  RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL 116
           RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL
Sbjct: 61  RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL 120

Query: 117 FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV 176
           FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV
Sbjct: 121 FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV 180

Query: 177 HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD 236
           HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD
Sbjct: 181 HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD 240

Query: 237 NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV 296
           NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV
Sbjct: 241 NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV 300

Query: 297 SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSE 356
           SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSE
Sbjct: 301 SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSE 360

Query: 357 SARPESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHS 416
           SARPESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHS
Sbjct: 361 SARPESETEDVLWEDLLHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLHS 420

Query: 417 SHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTP 476
           SHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTP
Sbjct: 421 SHPGLEKISAIVWEGNDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTP 480

Query: 477 FVFRLSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVA 536
           FVFRLSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVA
Sbjct: 481 FVFRLSQATDLEQLTAHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVA 540

Query: 537 ERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDV 596
           ERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDV
Sbjct: 541 ERTYKQRLLFAKLFGHLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDV 600

Query: 597 IVSSAFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKK 656
           IVSSAFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKK
Sbjct: 601 IVSSAFLLTISVVFICCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKK 660

Query: 657 YSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLL 716
           YSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLL
Sbjct: 661 YSNTSILLTEQINLYLKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLL 720

Query: 717 YNITQVVILSAVSGVISDLLGFNLKLWKIKS 747
           YNITQVVILSAVSGVISDLLGFNLKLWKIKS
Sbjct: 721 YNITQVVILSAVSGVISDLLGFNLKLWKIKS 751


>gi|166197666 putative homeodomain transcription factor 1 [Homo
           sapiens]
          Length = 762

 Score =  777 bits (2006), Expect = 0.0
 Identities = 431/796 (54%), Positives = 535/796 (67%), Gaps = 83/796 (10%)

Query: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
           MAS   DAI WYQKKIGAYDQQIWEKS+EQ +IKGL+NKPKK  H+KPDLIDVDL+RGS 
Sbjct: 1   MASNERDAISWYQKKIGAYDQQIWEKSIEQTQIKGLKNKPKKMGHIKPDLIDVDLIRGST 60

Query: 61  FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
           FAKAKPE PWTSLTRKG+VRVVFFP F  WW+QVTS  IF WLL+LY +QV AIVL+   
Sbjct: 61  FAKAKPEIPWTSLTRKGLVRVVFFPLFSNWWIQVTSLRIFVWLLLLYFMQVIAIVLYLMM 120

Query: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
                + ++EV+GP+ LMLL+GTVHCQIVST+  +P  + G +RRRKLRK  +      G
Sbjct: 121 P---IVNISEVLGPLCLMLLMGTVHCQIVSTQITRPSGNNGNRRRRKLRKTVN------G 171

Query: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
           DGS    N     V+  G  T  SV  +    W    F +  K+ K   +K TETDN   
Sbjct: 172 DGSRENGNNSSDKVR--GIETLESV-PIIGGFWE-TIFGNRIKRVKLISNKGTETDN--- 224

Query: 241 SLDGKKTVKSGEDGIQNHEPQC-------ETIRPEETAWNT---GTLRNGPS--KDTQRT 288
                             +P C          RPE   W T       +G    ++  R 
Sbjct: 225 ------------------DPSCVHPIIKRRQCRPEIRMWQTREKAKFSDGEKCRREAFRR 266

Query: 289 ITN-VSDEVSSEEGPETGYS---LRRHVDRTSEG---VLRNRK---SHHYKKHYPN---- 334
           + N VSD++SSEE  E       LRR V+  S      ++NRK   S H           
Sbjct: 267 LGNGVSDDLSSEEDGEARTQMILLRRSVEGASSDNGCEVKNRKSILSRHLNSQVKKTTTR 326

Query: 335 ---------------------EDAPKSGTSCSSR-CSSSRQDSESARPESETEDVLWEDL 372
                                    +SG S  SR  + SR+DSES R +SETED+LW+DL
Sbjct: 327 WCHIVRDSDSLAESEFESAAFSQGSRSGVSGGSRSLNMSRRDSESTRHDSETEDMLWDDL 386

Query: 373 LHCAECHSSCTSETD-VENHQINPCVKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEG 431
           LH  EC SS TS+++    + ++   K++ ++D F Q+HL WL +S P  +++SAI+WEG
Sbjct: 387 LHGPECRSSVTSDSEGAHVNTLHSGTKRDPKEDVFQQNHLFWLQNSSPSSDRVSAIIWEG 446

Query: 432 NDCKKADMSVLEISGMIMNRVNSHIPGIGYQIFGNAVSLILGLTPFVFRLSQATDLEQLT 491
           N+CKK DMSVLEISG+IM+RVN++  G+GYQ+ GN V++ L   PF+ RL +   L+QL 
Sbjct: 447 NECKKMDMSVLEISGIIMSRVNAYQQGVGYQMLGNVVTIGLAFFPFLHRLFREKSLDQLK 506

Query: 492 AHSASELYVIAFGSNEDVIVLSMVIISFVVRVSLVWIFFFLLCVAERTYKQRLLFAKLFG 551
           + SA E+  +  G+     ++ + II+F  R+ L W+FFF++CVAERTYKQR LFAKLF 
Sbjct: 507 SISAEEILTLFCGAPPVTPIIVLSIINFFERLCLTWMFFFMMCVAERTYKQRFLFAKLFS 566

Query: 552 HLTSARRARKSEVPHFRLKKVQNIKMWLSLRSYLKRRGPQRSVDVIVSSAFLLTISVVFI 611
           H+TSAR+ARK E+PHFRLKKV+NIK+WLSLRSYLKRRGPQRSVDV+VSS FLLT+S+ FI
Sbjct: 567 HITSARKARKYEIPHFRLKKVENIKIWLSLRSYLKRRGPQRSVDVVVSSVFLLTLSIAFI 626

Query: 612 CCAQLLHVHEIFLDCHYNWELVIWCISLTLFLLRFVTLGSETSKKYSNTSILLTEQINLY 671
           CCAQ+L  H+ FL+  YNWE +IW  +L LFLLR  +LGSET+KKYSN SILLTEQINLY
Sbjct: 627 CCAQVLQGHKTFLNDAYNWEFLIWETALLLFLLRLASLGSETNKKYSNVSILLTEQINLY 686

Query: 672 LKMEKKPNKKEELTLVNNVLKLATKLLKELDSPFRLYGLTMNPLLYNITQVVILSAVSGV 731
           LKMEKKPNKKE+LTLVNNVLKL+TKLLKELD+PFRLYGLTMNPL+YNIT+VVILSAVSGV
Sbjct: 687 LKMEKKPNKKEQLTLVNNVLKLSTKLLKELDTPFRLYGLTMNPLIYNITRVVILSAVSGV 746

Query: 732 ISDLLGFNLKLWKIKS 747
           ISDLLGFN++LWKIKS
Sbjct: 747 ISDLLGFNIRLWKIKS 762


>gi|188219575 putative homeodomain transcription factor 2 isoform 4
           [Homo sapiens]
          Length = 352

 Score =  687 bits (1773), Expect = 0.0
 Identities = 335/335 (100%), Positives = 335/335 (100%)

Query: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60
           MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA
Sbjct: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKGLRNKPKKTAHVKPDLIDVDLVRGSA 60

Query: 61  FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120
           FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST
Sbjct: 61  FAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVLFCST 120

Query: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180
           SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG
Sbjct: 121 SSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEVHREG 180

Query: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240
           DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV
Sbjct: 181 DGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYV 240

Query: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300
           SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE
Sbjct: 241 SLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEE 300

Query: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE 335
           GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE
Sbjct: 301 GPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE 335


>gi|188219573 putative homeodomain transcription factor 2 isoform 3
           [Homo sapiens]
          Length = 356

 Score =  681 bits (1758), Expect = 0.0
 Identities = 335/339 (98%), Positives = 335/339 (98%), Gaps = 4/339 (1%)

Query: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIK----GLRNKPKKTAHVKPDLIDVDLV 56
           MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIK    GLRNKPKKTAHVKPDLIDVDLV
Sbjct: 1   MASKVTDAIVWYQKKIGAYDQQIWEKSVEQREIKFIKLGLRNKPKKTAHVKPDLIDVDLV 60

Query: 57  RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL 116
           RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL
Sbjct: 61  RGSAFAKAKPESPWTSLTRKGIVRVVFFPFFFRWWLQVTSKVIFFWLLVLYLLQVAAIVL 120

Query: 117 FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV 176
           FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV
Sbjct: 121 FCSTSSPHSIPLTEVIGPIWLMLLLGTVHCQIVSTRTPKPPLSTGGKRRRKLRKAAHLEV 180

Query: 177 HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD 236
           HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD
Sbjct: 181 HREGDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETD 240

Query: 237 NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV 296
           NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV
Sbjct: 241 NGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEV 300

Query: 297 SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE 335
           SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE
Sbjct: 301 SSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNE 339


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 38.9 bits (89), Expect = 0.018
 Identities = 67/275 (24%), Positives = 104/275 (37%), Gaps = 40/275 (14%)

Query: 159  STGGK---RRRKLRKAAHLEVHREGDGS----------STTDNTQEGAVQNHGTSTSHSV 205
            STGG+   R  + R ++     +EG  +              +  E +V   G S SH  
Sbjct: 3730 STGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSVDRSGHSGSHHS 3789

Query: 206  GTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETI 265
             T  +    A+   SGS+ A      S ET N   S DG     S   G ++HE   +  
Sbjct: 3790 HTTSQGRSDASHGQSGSRSA------SRETRNEEQSGDG-----SRHSGSRHHEASTQAD 3838

Query: 266  RPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRNRKS 325
                +   +G   +  S+ ++R  ++VS +  SE  PE         +R SE   RN   
Sbjct: 3839 SSRHS--QSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDS-------ERRSESASRN--- 3886

Query: 326  HHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESET--EDVLWEDLLHCAECHSSCT 383
            HH      + D  +   S S R ++S   S   + +S T  E   +  L   +  HS   
Sbjct: 3887 HHGSSREQSRDGSRHPGS-SHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQ 3945

Query: 384  SETDVENHQINPCVKKEYRDDPFHQSHLPWLHSSH 418
            S     +   +   + E  +    QS L W H S+
Sbjct: 3946 SRGSPHSSS-SYHYQSEGTERQKGQSGLVWRHGSY 3979



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 57/231 (24%), Positives = 93/231 (40%), Gaps = 40/231 (17%)

Query: 159 STGGKR---RRKLRKAAHLEVHREGD-------GSST---TDNTQEGAVQNHGTSTSHSV 205
           STGG++     + R ++     +EG        GSS      +  E +V   G S SH  
Sbjct: 488 STGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHS 547

Query: 206 GTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETI 265
            T  +    A+   SGS+ A      S +T N   S DG +       G ++HE   +  
Sbjct: 548 HTTSQGRSDASHGQSGSRSA------SRQTRNEEQSGDGTR-----HSGSRHHEASSQAD 596

Query: 266 RPEETAWNTGTLRNGP--SKDTQRTITNVSDEVSSEEGPE--TGYSLRRH---VDRTSEG 318
               +    G   +GP  S++   +++  SD     E  E  +G + R H       S  
Sbjct: 597 SSRHSQVGQGQ-SSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRD 655

Query: 319 VLRNRKSHHYKK---HYPNEDAPKSGT-----SCSSRCSSSRQDSESARPE 361
             R+ +SHH  +    +  + + KSGT     S S + +SS + + S+  E
Sbjct: 656 GSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGE 706



 Score = 30.4 bits (67), Expect = 6.3
 Identities = 38/170 (22%), Positives = 62/170 (36%), Gaps = 16/170 (9%)

Query: 191  EGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKS 250
            E +V   G S SH   T  +    A+   SGS+ A     K  ++ +G           S
Sbjct: 1182 EQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDG-----------S 1230

Query: 251  GEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRR 310
               G ++HE          +    G  ++  S+ ++   ++VS +  SE   +    L  
Sbjct: 1231 RHSGSRHHEAASWADSSRHS--QVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSG 1288

Query: 311  HVDRTSEGVLRNRKSHHYKKH--YPNEDAPKSGTSCSSRCSSSRQDSESA 358
               R   G  R  +S    +H  +  ED    G S  S   S    +ES+
Sbjct: 1289 SASRNHHGSSR-EQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESS 1337


>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
           sapiens]
          Length = 1094

 Score = 37.7 bits (86), Expect = 0.039
 Identities = 36/148 (24%), Positives = 64/148 (43%), Gaps = 29/148 (19%)

Query: 218 FLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTL 277
           F S S++ ++S D S+++++   S  G++  +SGE+G  N +                  
Sbjct: 675 FYSESEEEEDSSDSSSDSESESGSESGEQG-ESGEEGDSNEDS----------------- 716

Query: 278 RNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDA 337
               S+D+       S E  SE G E+G   +R   R S+   ++      K++  ++ +
Sbjct: 717 ----SEDS-------SSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTS 765

Query: 338 PKSGTSCSSRCSSSRQDSESARPESETE 365
             S    SS   SS      + PESE+E
Sbjct: 766 DSSNDESSSIEDSSSDSESESEPESESE 793


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 37.4 bits (85), Expect = 0.051
 Identities = 42/180 (23%), Positives = 65/180 (36%), Gaps = 9/180 (5%)

Query: 183 SSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSL 242
           S TT N    A  +  ++TS    T       ++   SG+  A NS   +T +  G  + 
Sbjct: 215 SRTTSNGAGTATNSESSTTSSGASTATNS--ESSTPSSGAGTATNSESSTTSSGAGTATN 272

Query: 243 DGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGP 302
               TV SG   + N E    +     +  NT T     +  +       SD  ++  G 
Sbjct: 273 SESSTVSSGISTVTNSESSTPS-----SGANTATNSESSTTSSGANTATNSDSSTTSSGA 327

Query: 303 ETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPES 362
            T  +       TS G      S           A  SG+S +S  +S+  +SES+   S
Sbjct: 328 ST--ATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSS 385


>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 37.0 bits (84), Expect = 0.067
 Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 26/193 (13%)

Query: 222 SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGP 281
           S + +++I   T   + Y +++   ++KS +   +N    C+ ++    A    +   G 
Sbjct: 555 SLRKRDTITDKTARTSSYKAMEAASSLKS-QAATKNLSDACKPLKKRNRASTAASSALGF 613

Query: 282 SKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRT-SEGVLRNRKSHH---YKKHYPNEDA 337
           SK +  + +   +EVS   G E   S     D T +E  + ++KS      KK Y  +  
Sbjct: 614 SKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLC 673

Query: 338 PKSGT--SCSSRCSSSRQDS---ESARPESETEDVLWEDLLHCAECHS---SC----TSE 385
            K G+   C   C  +   +    S RPE             C+EC S   SC     S+
Sbjct: 674 EKPGSLLLCEGPCCGAFHLACLGLSRRPEGR---------FTCSECASGIHSCFVCKESK 724

Query: 386 TDVENHQINPCVK 398
           TDV+   +  C K
Sbjct: 725 TDVKRCVVTQCGK 737


>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 37.0 bits (84), Expect = 0.067
 Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 26/193 (13%)

Query: 222 SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGP 281
           S + +++I   T   + Y +++   ++KS +   +N    C+ ++    A    +   G 
Sbjct: 555 SLRKRDTITDKTARTSSYKAMEAASSLKS-QAATKNLSDACKPLKKRNRASTAASSALGF 613

Query: 282 SKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRT-SEGVLRNRKSHH---YKKHYPNEDA 337
           SK +  + +   +EVS   G E   S     D T +E  + ++KS      KK Y  +  
Sbjct: 614 SKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLC 673

Query: 338 PKSGT--SCSSRCSSSRQDS---ESARPESETEDVLWEDLLHCAECHS---SC----TSE 385
            K G+   C   C  +   +    S RPE             C+EC S   SC     S+
Sbjct: 674 EKPGSLLLCEGPCCGAFHLACLGLSRRPEGR---------FTCSECASGIHSCFVCKESK 724

Query: 386 TDVENHQINPCVK 398
           TDV+   +  C K
Sbjct: 725 TDVKRCVVTQCGK 737


>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 37.0 bits (84), Expect = 0.067
 Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 26/193 (13%)

Query: 222 SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGP 281
           S + +++I   T   + Y +++   ++KS +   +N    C+ ++    A    +   G 
Sbjct: 555 SLRKRDTITDKTARTSSYKAMEAASSLKS-QAATKNLSDACKPLKKRNRASTAASSALGF 613

Query: 282 SKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRT-SEGVLRNRKSHH---YKKHYPNEDA 337
           SK +  + +   +EVS   G E   S     D T +E  + ++KS      KK Y  +  
Sbjct: 614 SKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLC 673

Query: 338 PKSGT--SCSSRCSSSRQDS---ESARPESETEDVLWEDLLHCAECHS---SC----TSE 385
            K G+   C   C  +   +    S RPE             C+EC S   SC     S+
Sbjct: 674 EKPGSLLLCEGPCCGAFHLACLGLSRRPEGR---------FTCSECASGIHSCFVCKESK 724

Query: 386 TDVENHQINPCVK 398
           TDV+   +  C K
Sbjct: 725 TDVKRCVVTQCGK 737


>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
           [Homo sapiens]
          Length = 1365

 Score = 37.0 bits (84), Expect = 0.067
 Identities = 46/193 (23%), Positives = 78/193 (40%), Gaps = 26/193 (13%)

Query: 222 SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGP 281
           S + +++I   T   + Y +++   ++KS +   +N    C+ ++    A    +   G 
Sbjct: 555 SLRKRDTITDKTARTSSYKAMEAASSLKS-QAATKNLSDACKPLKKRNRASTAASSALGF 613

Query: 282 SKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRT-SEGVLRNRKSHH---YKKHYPNEDA 337
           SK +  + +   +EVS   G E   S     D T +E  + ++KS      KK Y  +  
Sbjct: 614 SKSSSPSASLTENEVSDSPGDEPSESPYESADETQTEVSVSSKKSERGVTAKKEYVCQLC 673

Query: 338 PKSGT--SCSSRCSSSRQDS---ESARPESETEDVLWEDLLHCAECHS---SC----TSE 385
            K G+   C   C  +   +    S RPE             C+EC S   SC     S+
Sbjct: 674 EKPGSLLLCEGPCCGAFHLACLGLSRRPEGR---------FTCSECASGIHSCFVCKESK 724

Query: 386 TDVENHQINPCVK 398
           TDV+   +  C K
Sbjct: 725 TDVKRCVVTQCGK 737


>gi|150418009 transforming, acidic coiled-coil containing protein 2
            isoform a [Homo sapiens]
          Length = 2948

 Score = 36.2 bits (82), Expect = 0.11
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 8/70 (11%)

Query: 243  DGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPS-------KDTQRTITNV-SD 294
            DGK  V S  +  + H+P+ + + PEE   +  + R GPS       KD  R +  V SD
Sbjct: 1789 DGKVCVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTSD 1848

Query: 295  EVSSEEGPET 304
            E    EG E+
Sbjct: 1849 ETRGAEGTES 1858


>gi|169213065 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 851

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 36/166 (21%), Positives = 58/166 (34%), Gaps = 6/166 (3%)

Query: 201 TSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEP 260
           T H VG        A+    G  + ++  + ++ T++G    DG +     E G+   E 
Sbjct: 62  TEHDVGQEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVNQEDGPEDASPTEHGVDQQED 121

Query: 261 QCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVL 320
             E  RP E   +     +GP +D   T   V  +   E+GPE        +D+  +G  
Sbjct: 122 GPEDARPTEHGIDQE--EDGP-EDASLTEHGVDQQ---EDGPEDASPTEHGIDQEEDGPE 175

Query: 321 RNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETED 366
               + H       ED P+  +             E A P     D
Sbjct: 176 DASPTEHEHGVDQEEDGPEDASPTEHGVDQEEDGPEDASPTEHGVD 221


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 50/230 (21%), Positives = 85/230 (36%), Gaps = 17/230 (7%)

Query: 151  TRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQN---HGTSTSHSVGT 207
            T + K  +    K+R  LR +      ++ D +S++ +  E   QN    G+S    +  
Sbjct: 1134 TSSKKKAVIVKEKKRNSLRTSTK---RKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP 1190

Query: 208  VFRDLW---HAAFFLSG-----SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHE 259
            V  +L    H  F  S      SK    ++D   + ++    +  K  ++  +  + + E
Sbjct: 1191 VTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDE 1250

Query: 260  PQCETIRPEETAWNTGTLRN-GPSKDTQRTITNVSDEVSSEEG--PETGYSLRRHVDRTS 316
                   PEE    TG      P  +  +   N   +  SEE   P   + L RH    S
Sbjct: 1251 DGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVS 1310

Query: 317  EGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETED 366
            +G     K    K+H   +   +   S      S  Q+S  +   SE+ED
Sbjct: 1311 DGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1360


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 35.4 bits (80), Expect = 0.19
 Identities = 50/230 (21%), Positives = 85/230 (36%), Gaps = 17/230 (7%)

Query: 151  TRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGSSTTDNTQEGAVQN---HGTSTSHSVGT 207
            T + K  +    K+R  LR +      ++ D +S++ +  E   QN    G+S    +  
Sbjct: 1172 TSSKKKAVIVKEKKRNSLRTSTK---RKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKP 1228

Query: 208  VFRDLW---HAAFFLSG-----SKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHE 259
            V  +L    H  F  S      SK    ++D   + ++    +  K  ++  +  + + E
Sbjct: 1229 VTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIKANLSSDE 1288

Query: 260  PQCETIRPEETAWNTGTLRN-GPSKDTQRTITNVSDEVSSEEG--PETGYSLRRHVDRTS 316
                   PEE    TG      P  +  +   N   +  SEE   P   + L RH    S
Sbjct: 1289 DGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVS 1348

Query: 317  EGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETED 366
            +G     K    K+H   +   +   S      S  Q+S  +   SE+ED
Sbjct: 1349 DGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESED 1398


>gi|70610136 poly (ADP-ribose) glycohydrolase [Homo sapiens]
          Length = 976

 Score = 35.0 bits (79), Expect = 0.25
 Identities = 51/209 (24%), Positives = 79/209 (37%), Gaps = 42/209 (20%)

Query: 182 GSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAFFLSGSKKAKN----SIDKS-TETD 236
           G  T ++    + +N+ T     + +V +D     F+    +K +N    S+DKS TE  
Sbjct: 87  GIKTAESESLDSKENNNTRIESMMSSVQKD----NFYQHNVEKLENVSQLSLDKSPTEKS 142

Query: 237 NGYVSL-----------DGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSKDT 285
             Y++            +GK T     + +   EPQ  T+ PE+  ++   +   P  D 
Sbjct: 143 TQYLNQHQTAAMCKWQNEGKHT-----EQLLESEPQTVTLVPEQ--FSNANIDRSPQNDD 195

Query: 286 QRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHY--KKHYPNEDAPKSGTS 343
                  S+E    +   T   L      T +   R  KSH    K   P ED       
Sbjct: 196 HSDTD--SEENRDNQQFLTTVKLANAKQTTEDEQAREAKSHQKCSKSCDPGED------- 246

Query: 344 CSSRCSSSRQDSESARPESETEDVLWEDL 372
               C+S +QD     PES   DV  ED+
Sbjct: 247 ----CASCQQDEIDVVPESPLSDVGSEDV 271


>gi|55749769 CWC22 spliceosome-associated protein homolog [Homo
           sapiens]
          Length = 908

 Score = 33.9 bits (76), Expect = 0.57
 Identities = 30/117 (25%), Positives = 46/117 (39%), Gaps = 21/117 (17%)

Query: 308 LRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDV 367
           LR H+  T + ++  +          N+ +P S +S SS   S   DS+S   +S +E  
Sbjct: 643 LREHLKNTPKVIVAQKPDVEQ-----NKSSPSSSSSASSSSESDSSDSDSDSSDSSSESS 697

Query: 368 LWEDLLHCAECHSSCTS--------------ETD--VENHQINPCVKKEYRDDPFHQ 408
             E        HSS ++              E D  + N Q N   +KE R +  HQ
Sbjct: 698 SEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQ 754


>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
           [Homo sapiens]
          Length = 2649

 Score = 33.5 bits (75), Expect = 0.74
 Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 10/71 (14%)

Query: 373 LHCAECHSSCTSETDVENHQINPCVKKEYRDDPFHQSHLPWLH-SSHPGLEKISA----- 426
           L+C  C  +C S+   ENH    C   E+         LPW H S  PGL K        
Sbjct: 40  LYCPACLVTCHSQEAFENH----CASSEHAQMVAFDQALPWEHRSPPPGLSKFELCPKPD 95

Query: 427 IVWEGNDCKKA 437
           +   G+ C KA
Sbjct: 96  LCEYGDACTKA 106


>gi|169213233 PREDICTED: similar to hCG1654128 [Homo sapiens]
          Length = 1070

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 36/166 (21%), Positives = 58/166 (34%), Gaps = 8/166 (4%)

Query: 201 TSHSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEP 260
           T H VG        A+    G  + ++  + ++ T++G    DG +     E G+   E 
Sbjct: 283 TEHDVGQEEDGPEDASPTEHGVDQQEDGPEDASPTEHGVNQEDGPEDASPTEHGVDQQED 342

Query: 261 QCETIRPEETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVL 320
             E  RP E   +     +GP +D   T   V  +   E+GPE        +D+  +G  
Sbjct: 343 GPEDARPTEHGIDQE--EDGP-EDASLTEHGVDQQ---EDGPEDASPTEHGIDQEEDGPE 396

Query: 321 RNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETED 366
               + H       ED P+  +             E A P     D
Sbjct: 397 DASPTEHGVDQ--EEDGPEDASPTEHGVDQEEDGPEDASPTEHGVD 440


>gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]
          Length = 1090

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 39/181 (21%), Positives = 71/181 (39%), Gaps = 29/181 (16%)

Query: 203 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 262
           HS   V R+ W      +G+ + + +  + +E D        +  VK  ED IQ  E + 
Sbjct: 40  HSKSKVLREKWLLQGIPAGTAEEEEARRRQSEED--------EFRVKQLEDNIQRLEQEI 91

Query: 263 ETIRPEETAWNTGT-LRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLR 321
           +T+  EE+  +    +     K+T+++  +     SS +G    Y   +  D     +L 
Sbjct: 92  QTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQLPDLP---ILC 148

Query: 322 NRKSHHYKKHYPNEDAP-------------KSGTSCSSRCSSSRQDSESARPESETEDVL 368
           +R +    +  P +D               K G S S+   +S  D    +P   +ED +
Sbjct: 149 SRTA----EPSPGQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQLSEDDI 204

Query: 369 W 369
           W
Sbjct: 205 W 205


>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
          Length = 1103

 Score = 32.7 bits (73), Expect = 1.3
 Identities = 39/181 (21%), Positives = 71/181 (39%), Gaps = 29/181 (16%)

Query: 203 HSVGTVFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQC 262
           HS   V R+ W      +G+ + + +  + +E D        +  VK  ED IQ  E + 
Sbjct: 40  HSKSKVLREKWLLQGIPAGTAEEEEARRRQSEED--------EFRVKQLEDNIQRLEQEI 91

Query: 263 ETIRPEETAWNTGT-LRNGPSKDTQRTITNVSDEVSSEEGPETGYSLRRHVDRTSEGVLR 321
           +T+  EE+  +    +     K+T+++  +     SS +G    Y   +  D     +L 
Sbjct: 92  QTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGDAVNYISSQLPDLP---ILC 148

Query: 322 NRKSHHYKKHYPNEDAP-------------KSGTSCSSRCSSSRQDSESARPESETEDVL 368
           +R +    +  P +D               K G S S+   +S  D    +P   +ED +
Sbjct: 149 SRTA----EPSPGQDGTSRAAGVGWENVLLKEGESASNATETSGPDMTIKKPPQLSEDDI 204

Query: 369 W 369
           W
Sbjct: 205 W 205


>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
           sapiens]
          Length = 1723

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 42/199 (21%), Positives = 76/199 (38%), Gaps = 23/199 (11%)

Query: 180 GDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAF------FLSGSKKAKNSIDKST 233
           G G   T  + +   Q+ G   + SVG+     W AA        +SG   + N+ +   
Sbjct: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGS-----WGAARGPSGTDTVSGQSNSGNNGNNGK 451

Query: 234 ETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSK--DTQRTITN 291
           E ++ +     +K+  S  D   N+       R    +WN G   +  +K  +  +  + 
Sbjct: 452 EREDSWKGASVQKSTGSKNDSWDNNN------RSTGGSWNFGPQDSNDNKWGEGNKMTSG 505

Query: 292 VSD----EVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSR 347
           VS     + +  +  + G     +   +S G   N+K H   ++  N  AP  G S SS 
Sbjct: 506 VSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSST 565

Query: 348 CSSSRQDSESARPESETED 366
            S     S  +  ++ + D
Sbjct: 566 GSEVGGQSTGSNHKAGSSD 584


>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
           sapiens]
          Length = 1833

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 42/199 (21%), Positives = 76/199 (38%), Gaps = 23/199 (11%)

Query: 180 GDGSSTTDNTQEGAVQNHGTSTSHSVGTVFRDLWHAAF------FLSGSKKAKNSIDKST 233
           G G   T  + +   Q+ G   + SVG+     W AA        +SG   + N+ +   
Sbjct: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGS-----WGAARGPSGTDTVSGQSNSGNNGNNGK 451

Query: 234 ETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGTLRNGPSK--DTQRTITN 291
           E ++ +     +K+  S  D   N+       R    +WN G   +  +K  +  +  + 
Sbjct: 452 EREDSWKGASVQKSTGSKNDSWDNNN------RSTGGSWNFGPQDSNDNKWGEGNKMTSG 505

Query: 292 VSD----EVSSEEGPETGYSLRRHVDRTSEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSR 347
           VS     + +  +  + G     +   +S G   N+K H   ++  N  AP  G S SS 
Sbjct: 506 VSQGEWKQPTGSDELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQAPCWGRSSSST 565

Query: 348 CSSSRQDSESARPESETED 366
            S     S  +  ++ + D
Sbjct: 566 GSEVGGQSTGSNHKAGSSD 584


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 32.0 bits (71), Expect = 2.2
 Identities = 51/227 (22%), Positives = 85/227 (37%), Gaps = 32/227 (14%)

Query: 229  IDKSTET--DNGYVSLDGKKTVKSGEDGIQNHEPQCETIR-PEETAWNTGTLR------- 278
            I+++T++  D+GY      KT K+ EDG  ++E   +T R PEE  ++            
Sbjct: 1909 IERTTKSPSDSGYSYETIGKTTKTPEDGDYSYEIIEKTTRTPEEGGYSYDISEKTTSPPE 1968

Query: 279  -NGPSKDTQRTITNVSDEVS-----SEEGPET----GYSLRRHVDRTSEGVLRNRKSHHY 328
             +G S +       + D++S     SE+G  T     YS       TS       + + Y
Sbjct: 1969 VSGYSYEKTERSRRLLDDISNGYDDSEDGGHTLGDPSYSYETTEKITS---FPESEGYSY 2025

Query: 329  KKHYPNEDAPKSGTSCSSRCSSSRQDSESARPESETEDVLWEDLLHCAECHSSCTSETDV 388
            +        P + T C         +  +  P++ T      DL + AE  S   +  DV
Sbjct: 2026 ETSTKTTRTPDTSTYCYETA-----EKITRTPQASTYSYETSDLCYTAEKKSPSEARQDV 2080

Query: 389  ENHQINPC----VKKEYRDDPFHQSHLPWLHSSHPGLEKISAIVWEG 431
            +   ++ C     K E      + + L W  S  P  E    +   G
Sbjct: 2081 DLCLVSSCEYKHPKTELSPSFINPNPLEWFASEEPTEESEKPLTQSG 2127


>gi|62241003 cardiomyopathy associated 5 [Homo sapiens]
          Length = 4069

 Score = 31.6 bits (70), Expect = 2.8
 Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 9/77 (11%)

Query: 234  ETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRPEETAWNTGT-------LRNG-PSKDT 285
            E +N  +S +G   ++     + +H  + E  +  E  W  G+       ++ G PSK++
Sbjct: 2733 EIENHSLSQEGNLVLEKSSRDMPDHSEEKEQFKESEL-WKGGSVDITKESMKEGFPSKES 2791

Query: 286  QRTITNVSDEVSSEEGP 302
            +RT+    DE  S E P
Sbjct: 2792 ERTLARPFDETKSSETP 2808


>gi|109637791 transcription factor-like nuclear regulator [Homo
           sapiens]
          Length = 2624

 Score = 31.6 bits (70), Expect = 2.8
 Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 1/121 (0%)

Query: 149 VSTRTPKPPLSTGGKRRRKLRKAAHLEVHREGDGS-STTDNTQEGAVQNHGTSTSHSVGT 207
           V   + K   ST  ++  K++K A   V+ + D S S+  +  E + ++  T    S+  
Sbjct: 386 VKNHSLKEKKSTKPRKNVKVKKVACEGVNNDPDESMSSRISDTERSQKDAQTVEEESLTL 445

Query: 208 VFRDLWHAAFFLSGSKKAKNSIDKSTETDNGYVSLDGKKTVKSGEDGIQNHEPQCETIRP 267
              D    A  +  ++K +    +    + G  +L    TV++G    + H+ +C+ IRP
Sbjct: 446 SREDAEQVALEVDLNQKKRRRKKQDGANELGVNNLLENATVQAGPSKGEKHKNKCQAIRP 505

Query: 268 E 268
           E
Sbjct: 506 E 506


>gi|222831577 zinc finger protein 286B [Homo sapiens]
          Length = 522

 Score = 31.2 bits (69), Expect = 3.7
 Identities = 21/102 (20%), Positives = 46/102 (45%), Gaps = 15/102 (14%)

Query: 316 SEGVLRNRKSHHYKKHYPNEDAPKSGTSCSSRCSSSR--------QDSESARPESETEDV 367
           S  +++++++H  +K Y  ++  K+ + CSS     R        + SE  +  S++  +
Sbjct: 367 SSALIKHQRTHTGEKPYKCQECGKAFSHCSSLTKHQRVHTGEKPYECSECGKTFSQSTHL 426

Query: 368 LWEDLLH-------CAECHSSCTSETDVENHQINPCVKKEYR 402
           +    +H       C+EC  + +  ++   HQ     KK Y+
Sbjct: 427 VQHQRIHTGEKPYECSECGKTFSQSSNFAKHQRIHIGKKPYK 468


>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
          Length = 755

 Score = 31.2 bits (69), Expect = 3.7
 Identities = 36/152 (23%), Positives = 61/152 (40%), Gaps = 12/152 (7%)

Query: 268 EETAWNTGTLRNGPSKDTQRTITNVSDEVSSEEG-PETGYSLRRHVDRTSEG-VLRNRKS 325
           EE A       + P K+ +        E  SEEG P+ G+        + EG  +R  + 
Sbjct: 441 EEGASENNAKESSPEKEAEEGCP----EKESEEGCPKRGFEGSCSQKESEEGNPVRGSEE 496

Query: 326 HHYKKHYPNE----DAPKSGTSCSSRCSSSRQDSESARP--ESETEDVLWEDLLHCAECH 379
              KK    +    D  ++G +  S    +++  E   P  ESE +D   E    C+E  
Sbjct: 497 DSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQ 556

Query: 380 SSCTSETDVENHQINPCVKKEYRDDPFHQSHL 411
           S   SE + E + +   + +E  +   H++ L
Sbjct: 557 SEDGSEREFEENGLEKDLDEEGSEKELHENVL 588


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,761,470
Number of Sequences: 37866
Number of extensions: 1241463
Number of successful extensions: 4541
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 39
Number of HSP's that attempted gapping in prelim test: 4482
Number of HSP's gapped (non-prelim): 88
length of query: 747
length of database: 18,247,518
effective HSP length: 110
effective length of query: 637
effective length of database: 14,082,258
effective search space: 8970398346
effective search space used: 8970398346
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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