Search of human proteins with 187936935

Search of human proteins with 187936935

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187936935 GRAM domain containing 1C [Homo sapiens]
         (662 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187936935 GRAM domain containing 1C [Homo sapiens]                1301   0.0  
gi|144227752 GRAM domain containing 1B [Homo sapiens]                 466   e-131
gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]       439   e-123
gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]        438   e-123
gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]         97   4e-20
gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]         97   4e-20
gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]         97   4e-20
gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]         97   4e-20
gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]         94   5e-19
gi|60593095 GRAM domain containing 2 [Homo sapiens]                    90   8e-18
gi|45597177 TBC1 domain family, member 9B (with GRAM domain) iso...    55   2e-07
gi|45597175 TBC1 domain family, member 9B (with GRAM domain) iso...    55   2e-07
gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Ho...    54   6e-07
gi|38570103 TBC1 domain family, member 8B (with GRAM domain) iso...    47   4e-05
gi|38570101 TBC1 domain family, member 8B (with GRAM domain) iso...    47   4e-05
gi|156231067 TBC1 domain family, member 8 [Homo sapiens]               41   0.003
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    38   0.026
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    38   0.034
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    37   0.045
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]     37   0.076
gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]      37   0.076
gi|191250773 spire homolog 1 isoform a [Homo sapiens]                  37   0.076
gi|40255119 RAS and EF-hand domain containing [Homo sapiens]           35   0.22 
gi|105990532 apolipoprotein B precursor [Homo sapiens]                 34   0.38 
gi|16554564 caspase recruitment domain family, member 6 [Homo sa...    34   0.38 
gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo s...    34   0.49 
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    34   0.49 
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 33   0.64 
gi|16262452 cingulin [Homo sapiens]                                    33   0.64 
gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens]       33   0.64 

>gi|187936935 GRAM domain containing 1C [Homo sapiens]
          Length = 662

 Score = 1301 bits (3368), Expect = 0.0
 Identities = 662/662 (100%), Positives = 662/662 (100%)

Query: 1   MEGAPTVRQVMNEGDSSLATDLQEDVEENPSPTVEENNVVVKKQGPNLHNWSGDWSFWIS 60
           MEGAPTVRQVMNEGDSSLATDLQEDVEENPSPTVEENNVVVKKQGPNLHNWSGDWSFWIS
Sbjct: 1   MEGAPTVRQVMNEGDSSLATDLQEDVEENPSPTVEENNVVVKKQGPNLHNWSGDWSFWIS 60

Query: 61  SSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWET 120
           SSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWET
Sbjct: 61  SSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWET 120

Query: 121 TISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDK 180
           TISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDK
Sbjct: 121 TISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDK 180

Query: 181 SLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEDVQPRSPGRSSLDDSGERDEKLSKSI 240
           SLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEDVQPRSPGRSSLDDSGERDEKLSKSI
Sbjct: 181 SLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEDVQPRSPGRSSLDDSGERDEKLSKSI 240

Query: 241 SFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTRVPSKSLDLNK 300
           SFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTRVPSKSLDLNK
Sbjct: 241 SFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTRVPSKSLDLNK 300

Query: 301 NEYLSLDKSSTSDSVDEENVPEKDLHGRLFINRIFHISADRMFELLFTSSRFMQKFASSR 360
           NEYLSLDKSSTSDSVDEENVPEKDLHGRLFINRIFHISADRMFELLFTSSRFMQKFASSR
Sbjct: 301 NEYLSLDKSSTSDSVDEENVPEKDLHGRLFINRIFHISADRMFELLFTSSRFMQKFASSR 360

Query: 361 NIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTGKCTAATEKQTLYKESREARFYLVDSE 420
           NIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTGKCTAATEKQTLYKESREARFYLVDSE
Sbjct: 361 NIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTGKCTAATEKQTLYKESREARFYLVDSE 420

Query: 421 VLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYRKQPWGLVKSLIEKNSWSSLED 480
           VLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYRKQPWGLVKSLIEKNSWSSLED
Sbjct: 421 VLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYRKQPWGLVKSLIEKNSWSSLED 480

Query: 481 YFKQLESDLLIEESVLNQAIEDPGKLTGLRRRRRTFNRTAETVPKLSSQHSSGDVGLGAK 540
           YFKQLESDLLIEESVLNQAIEDPGKLTGLRRRRRTFNRTAETVPKLSSQHSSGDVGLGAK
Sbjct: 481 YFKQLESDLLIEESVLNQAIEDPGKLTGLRRRRRTFNRTAETVPKLSSQHSSGDVGLGAK 540

Query: 541 GDITGKKKEMENYNVTLIVVMSIFVLLLVLLNVTLFLKLSKIEHAAQSFYRLRLQEEKSL 600
           GDITGKKKEMENYNVTLIVVMSIFVLLLVLLNVTLFLKLSKIEHAAQSFYRLRLQEEKSL
Sbjct: 541 GDITGKKKEMENYNVTLIVVMSIFVLLLVLLNVTLFLKLSKIEHAAQSFYRLRLQEEKSL 600

Query: 601 NLASDMVSRAETIQKNKDQAHRLKGVLRDSIVMLEQLKSSLIMLQKTFDLLNKNKTGMAV 660
           NLASDMVSRAETIQKNKDQAHRLKGVLRDSIVMLEQLKSSLIMLQKTFDLLNKNKTGMAV
Sbjct: 601 NLASDMVSRAETIQKNKDQAHRLKGVLRDSIVMLEQLKSSLIMLQKTFDLLNKNKTGMAV 660

Query: 661 ES 662
           ES
Sbjct: 661 ES 662


>gi|144227752 GRAM domain containing 1B [Homo sapiens]
          Length = 738

 Score =  466 bits (1199), Expect = e-131
 Identities = 276/687 (40%), Positives = 397/687 (57%), Gaps = 61/687 (8%)

Query: 15  DSSLATDLQEDVEENPSPTVEENNVVVK------KQGPNLHNWSGDWSFWISSSTYKDRN 68
           D     +   D   + SP+  E  V         + G      S  W + + S TYK RN
Sbjct: 37  DGDTMVEKGSDHSSDKSPSTPEQGVQRSCSSQSGRSGGKNSKKSQSW-YNVLSPTYKQRN 95

Query: 69  EEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKN 128
           E++R+ F  LPDTERLI DY+CALQRDILLQGRLYLSENW+CFYSNIFRWET +++ LK+
Sbjct: 96  EDFRKLFKQLPDTERLIVDYSCALQRDILLQGRLYLSENWICFYSNIFRWETLLTVRLKD 155

Query: 129 ITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDKSLTRQEFW 188
           I  MTKEKTARLIPNAIQ+ T+SEK FFTSFGARDR+Y+ +FRLWQN LL+K L  +E W
Sbjct: 156 ICSMTKEKTARLIPNAIQVCTDSEKHFFTSFGARDRTYMMMFRLWQNALLEKPLCPKELW 215

Query: 189 QLLQQNYGTELGLNAEEMENL-------------SLSIEDVQPR-SPGRSSLDDSGERDE 234
             + Q YG ELGL +++ + +              + +E+ +   S  +SS++   +   
Sbjct: 216 HFVHQCYGNELGLTSDDEDYVPPDDDFNTMGYCEEIPVEENEVNDSSSKSSIETKPDASP 275

Query: 235 KLSKSISFTSESISRVSETE---SFDG-NSSKGGLGKEESQNEKQTKKSLLPTLEKKLTR 290
           +L K  S T+ +++    +E   SFDG    +  L  + S  ++    +++    + +  
Sbjct: 276 QLPKK-SITNSTLTSTGSSEAPVSFDGLPLEEEALEGDGSLEKELAIDNIMGEKIEMIAP 334

Query: 291 VPSKSLDLNKNEYLSLDKSSTSDSVDEENVPE--KDLHGRLFINRIFHISADRMFELLFT 348
           V S SLD N NE +  + S +SD+ DE  V    +DL GR ++N +F+ S D++++LLFT
Sbjct: 335 VNSPSLDFNDNEDIPTELSDSSDTHDEGEVQAFYEDLSGRQYVNEVFNFSVDKLYDLLFT 394

Query: 349 SSRFMQKFASSRNIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTGKCTAATEKQTLYKE 408
           +S F + F   R   D++  PW  E  G+Q R + YTI L +PL  K     E QT+YK 
Sbjct: 395 NSPFQRDFMEQRRFSDIIFHPWKKEENGNQSRVILYTITLTNPLAPKTATVRETQTMYKA 454

Query: 409 SREARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYRKQPWGLVKS 468
           S+E+  Y++D+EVLTHDVPYHDYFYT+NRY + R ++ K RLRVST+L+YRKQPWGLVK+
Sbjct: 455 SQESECYVIDAEVLTHDVPYHDYFYTINRYTLTRVARNKSRLRVSTELRYRKQPWGLVKT 514

Query: 469 LIEKNSWSSLEDYFKQLESDLLIEESVL------NQAIEDPGKLTGLRRRRRTFNRTAET 522
            IEKN WS LEDYF+ LES+L   ES            E   K T +RRR+R        
Sbjct: 515 FIEKNFWSGLEDYFRHLESELAKTESTYLAEMHRQSPKEKASKTTTVRRRKRPHAHL--R 572

Query: 523 VPKLSS-----------------QHSSGDVGLGAKGDITGKKKEMENYNVTLIVVMSIF- 564
           VP L                   +H +G        + T     +++ +  L+V+  +  
Sbjct: 573 VPHLEEVMSPVTTPTDEDVGHRIKHVAGSTQTRHIPEDTPNGFHLQSVSKLLLVISCVIC 632

Query: 565 --VLLLVLLNVTLFLKLSKIEHAAQ---SFYRLRLQEEKSLNLASDMVSRAETIQKNKD- 618
             ++LLV+LN+ LF KL  +E+  Q   ++  LRLQE    +  ++     E+ QK  D 
Sbjct: 633 FSLVLLVILNMMLFYKLWMLEYTTQTLTAWQGLRLQERLPQS-QTEWAQLLESQQKYHDT 691

Query: 619 QAHRLKGVLRDSIVMLEQLKSSLIMLQ 645
           +  + + +++ S+++L+Q+K SLI LQ
Sbjct: 692 ELQKWREIIKSSVMLLDQMKDSLINLQ 718


>gi|209969686 GRAM domain containing 1A isoform 2 [Homo sapiens]
          Length = 713

 Score =  439 bits (1128), Expect = e-123
 Identities = 261/623 (41%), Positives = 370/623 (59%), Gaps = 42/623 (6%)

Query: 61  SSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWET 120
           S TYK RNE++R+ F+ LP+ ERLI DY+CALQR+ILLQGRLYLSENW+CFYSNIFRWET
Sbjct: 76  SPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWET 135

Query: 121 TISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQNVLLDK 180
           TISI LK +T + KEKTA+LIPNAIQI TESEK FFTSFGARDR +L IFRLWQN LL+K
Sbjct: 136 TISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEK 195

Query: 181 SLTRQEFWQLLQQNYGTELGLNAEEMENLS-LSIEDV-QPRSPG----RSSLDDSGERDE 234
           +L+ +E W L+ Q YG+ELGL +E+ + +S L +  +  P+  G     S +  SG  D 
Sbjct: 196 TLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLGTPKEVGDVIALSDITSSGAADR 255

Query: 235 KLSKS-----ISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLT 289
               S         + ++SR S          K    + +SQ +  + +++ P  E   T
Sbjct: 256 SQEPSPVGSRRGHVTPNLSRASSDADHGAEEDKE--EQVDSQPDASSSQTVTPVAEPPST 313

Query: 290 RVPSKS-------LDLNKNEYLSLDKSSTSDSVDEE---NVPEKDLHGRLFINRIFHISA 339
                        LDL  +E L  D S++S S  EE        DL GRL IN +FH+ A
Sbjct: 314 EPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSVFHVGA 373

Query: 340 DRMFELLFTSSRFMQKFASSRNIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTGKCTAA 399
           +R+ ++LF+ S F+Q F       DV  +PW+ +    Q R +TYTI +++PL  K  + 
Sbjct: 374 ERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASV 433

Query: 400 TEKQTLYKESREARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVSTDLKYR 459
            E QTL++   +A   +VDSEVLT  +PY DYFYT +RYCI+  ++ K RLRVS++++YR
Sbjct: 434 VETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYR 493

Query: 460 KQPWGLVKSLIEKNSWSSLEDYFKQLESDLLIEESVLNQAIEDPGK-----LTGLRRRRR 514
           KQPW LVKSLIEKNSWS +EDYF  LE +L   E +   ++E+ GK     L+GLRRR+R
Sbjct: 494 KQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKL---SLEEGGKDARGLLSGLRRRKR 550

Query: 515 TFN-RTAETVPKLSSQHSSGDVGLGAKGDITGKKKEMENYN------VTLIVVMSIFVLL 567
             + R     P+          G+   G ++ +  E            + +V++SI +++
Sbjct: 551 PLSWRAHGDGPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGPGAGIPSALVLISIVLII 610

Query: 568 LVLLNVTLFLKLSKIE---HAAQSFYRLRLQEEKSLNLASDMVS-RAETIQKNKDQAHRL 623
           L+ LNV LF +L  +E   H  +S++ L L + K    A++     A   Q +  + H+ 
Sbjct: 611 LIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKW 670

Query: 624 KGVLRDSIVMLEQLKSSLIMLQK 646
           + +LR S+ +L+++K SL  L +
Sbjct: 671 RQILRASVELLDEMKFSLEKLHQ 693


>gi|92110010 GRAM domain containing 1A isoform 1 [Homo sapiens]
          Length = 724

 Score =  438 bits (1127), Expect = e-123
 Identities = 262/632 (41%), Positives = 373/632 (59%), Gaps = 48/632 (7%)

Query: 58  WIS--SSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNI 115
           W S  S TYK RNE++R+ F+ LP+ ERLI DY+CALQR+ILLQGRLYLSENW+CFYSNI
Sbjct: 78  WYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNI 137

Query: 116 FRWETTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIFRLWQN 175
           FRWETTISI LK +T + KEKTA+LIPNAIQI TESEK FFTSFGARDR +L IFRLWQN
Sbjct: 138 FRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQN 197

Query: 176 VLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLS-LSIEDV-QPRSPG----RSSLDDS 229
            LL+K+L+ +E W L+ Q YG+ELGL +E+ + +S L +  +  P+  G     S +  S
Sbjct: 198 ALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLGTPKEVGDVIALSDITSS 257

Query: 230 GERDEKLSKS-----ISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTL 284
           G  D     S         + ++SR S          K    + +SQ +  + +++ P  
Sbjct: 258 GAADRSQEPSPVGSRRGHVTPNLSRASSDADHGAEEDKE--EQVDSQPDASSSQTVTPVA 315

Query: 285 EKKLTRVPSKS-------LDLNKNEYLSLDKSSTSDSVDEE---NVPEKDLHGRLFINRI 334
           E   T             LDL  +E L  D S++S S  EE        DL GRL IN +
Sbjct: 316 EPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSV 375

Query: 335 FHISADRMFELLFTSSRFMQKFASSRNIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTG 394
           FH+ A+R+ ++LF+ S F+Q F       DV  +PW+ +    Q R +TYTI +++PL  
Sbjct: 376 FHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGP 435

Query: 395 KCTAATEKQTLYKESREARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLRVST 454
           K  +  E QTL++   +A   +VDSEVLT  +PY DYFYT +RYCI+  ++ K RLRVS+
Sbjct: 436 KSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSS 495

Query: 455 DLKYRKQPWGLVKSLIEKNSWSSLEDYFKQLESDLLIEESVLNQAIEDPGK-----LTGL 509
           +++YRKQPW LVKSLIEKNSWS +EDYF  LE +L   E +   ++E+ GK     L+GL
Sbjct: 496 EIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKL---SLEEGGKDARGLLSGL 552

Query: 510 RRRRRTFN-RTAETVPKLSSQHSSGDVGLGAKGDITGKKKE----------MENYNVTLI 558
           RRR+R  + R     P+          G+   G ++ +  E          + +  V + 
Sbjct: 553 RRRKRPLSWRAHGDGPQHPDPDPCARAGIHTSGSLSSRFSEPSVDQGPGAGIPSALVLIS 612

Query: 559 VVMSIFVLLLVLLNVTLFLKLSKIE---HAAQSFYRLRLQEEKSLNLASDMVS-RAETIQ 614
           +V+ + +++L+ LNV LF +L  +E   H  +S++ L L + K    A++     A   Q
Sbjct: 613 IVICVSLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQ 672

Query: 615 KNKDQAHRLKGVLRDSIVMLEQLKSSLIMLQK 646
            +  + H+ + +LR S+ +L+++K SL  L +
Sbjct: 673 FHSVEVHKWRQILRASVELLDEMKFSLEKLHQ 704


>gi|226443028 GRAM domain containing 3 isoform 5 [Homo sapiens]
          Length = 416

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 1/107 (0%)

Query: 60  SSSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWE 119
           SSS YK  N  + + F  +P  E L   + CALQ++IL QG+L++SENW+CF+S +F  +
Sbjct: 86  SSSQYK-ANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKD 144

Query: 120 TTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSY 166
           T ISI   ++T + K KTA L+PNA+ I T ++++ F S  +RD +Y
Sbjct: 145 TKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTY 191


>gi|226443022 GRAM domain containing 3 isoform 4 [Homo sapiens]
          Length = 440

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 1/107 (0%)

Query: 60  SSSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWE 119
           SSS YK  N  + + F  +P  E L   + CALQ++IL QG+L++SENW+CF+S +F  +
Sbjct: 110 SSSQYK-ANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKD 168

Query: 120 TTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSY 166
           T ISI   ++T + K KTA L+PNA+ I T ++++ F S  +RD +Y
Sbjct: 169 TKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTY 215


>gi|226443011 GRAM domain containing 3 isoform 1 [Homo sapiens]
          Length = 447

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 1/107 (0%)

Query: 60  SSSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWE 119
           SSS YK  N  + + F  +P  E L   + CALQ++IL QG+L++SENW+CF+S +F  +
Sbjct: 117 SSSQYK-ANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKD 175

Query: 120 TTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSY 166
           T ISI   ++T + K KTA L+PNA+ I T ++++ F S  +RD +Y
Sbjct: 176 TKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTY 222


>gi|226443007 GRAM domain containing 3 isoform 2 [Homo sapiens]
          Length = 432

 Score = 97.4 bits (241), Expect = 4e-20
 Identities = 47/107 (43%), Positives = 71/107 (66%), Gaps = 1/107 (0%)

Query: 60  SSSTYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWE 119
           SSS YK  N  + + F  +P  E L   + CALQ++IL QG+L++SENW+CF+S +F  +
Sbjct: 102 SSSQYK-ANMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKD 160

Query: 120 TTISIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSY 166
           T ISI   ++T + K KTA L+PNA+ I T ++++ F S  +RD +Y
Sbjct: 161 TKISIPAFSVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTY 207


>gi|226443017 GRAM domain containing 3 isoform 3 [Homo sapiens]
          Length = 328

 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 42/99 (42%), Positives = 66/99 (66%)

Query: 68  NEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALK 127
           N  + + F  +P  E L   + CALQ++IL QG+L++SENW+CF+S +F  +T ISI   
Sbjct: 5   NMHFHKLFLSVPTEEPLKQSFTCALQKEILYQGKLFVSENWICFHSKVFGKDTKISIPAF 64

Query: 128 NITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSY 166
           ++T + K KTA L+PNA+ I T ++++ F S  +RD +Y
Sbjct: 65  SVTLIKKTKTALLVPNALIIATVTDRYIFVSLLSRDSTY 103


>gi|60593095 GRAM domain containing 2 [Homo sapiens]
          Length = 354

 Score = 89.7 bits (221), Expect = 8e-18
 Identities = 49/128 (38%), Positives = 78/128 (60%), Gaps = 3/128 (2%)

Query: 63  TYKDRNEEYRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTI 122
           T    N++Y + F  +P  E ++   +CALQRD LLQGRLY+S NWLCF++++F  +  +
Sbjct: 66  TLNKYNQQYHKLFKDVPLEEVVLKVCSCALQRDFLLQGRLYISPNWLCFHASLFGKDIKV 125

Query: 123 SIALKNITFMTKEKTARLIPNAIQIVTE-SEKFFFTSFGARDRSYLSIFRLWQNV--LLD 179
            I + ++  + K K ARL+PN + I T  S+K+ F S  +RD  Y  + R+  ++     
Sbjct: 126 VIPVVSVQMIKKHKMARLLPNGLAITTNTSQKYIFVSLLSRDSVYDLLRRVCTHLQPSSK 185

Query: 180 KSLTRQEF 187
           KSL+ +EF
Sbjct: 186 KSLSVREF 193


>gi|45597177 TBC1 domain family, member 9B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 1233

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 32/97 (32%), Positives = 57/97 (58%), Gaps = 3/97 (3%)

Query: 64  YKDRNEEYRRQFTHLPDTERLIADYACALQRD-ILLQGRLYLSENWLCFYSNIFRWETTI 122
           +K+   + R+QF  +P+ E+L+  Y+C+  +  +  QG LYL+ N LCFYS +   E ++
Sbjct: 137 FKEAELKMRKQFG-MPEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSL 195

Query: 123 SIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSF 159
            +   +IT + K  T  L P +I++ T  ++ FF+ F
Sbjct: 196 VVQWVDITRLEKNATL-LFPESIRVDTRDQELFFSMF 231


>gi|45597175 TBC1 domain family, member 9B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1250

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 32/97 (32%), Positives = 57/97 (58%), Gaps = 3/97 (3%)

Query: 64  YKDRNEEYRRQFTHLPDTERLIADYACALQRD-ILLQGRLYLSENWLCFYSNIFRWETTI 122
           +K+   + R+QF  +P+ E+L+  Y+C+  +  +  QG LYL+ N LCFYS +   E ++
Sbjct: 137 FKEAELKMRKQFG-MPEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSL 195

Query: 123 SIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSF 159
            +   +IT + K  T  L P +I++ T  ++ FF+ F
Sbjct: 196 VVQWVDITRLEKNATL-LFPESIRVDTRDQELFFSMF 231


>gi|139394668 TBC1 domain family, member 9 (with GRAM domain) [Homo
           sapiens]
          Length = 1266

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 33/97 (34%), Positives = 56/97 (57%), Gaps = 3/97 (3%)

Query: 64  YKDRNEEYRRQFTHLPDTERLIADYACALQRD-ILLQGRLYLSENWLCFYSNIFRWETTI 122
           +K+   ++ R F  +P+ E+L+  Y+C+  +  +  QG +YLS N LCFYS +   E  +
Sbjct: 141 FKEAIVKFHRLFG-MPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFYSFLMGREAKL 199

Query: 123 SIALKNITFMTKEKTARLIPNAIQIVTESEKFFFTSF 159
            I   +IT + K  T  L+P+ I++ T S + FF+ F
Sbjct: 200 VIRWVDITQLEKNATL-LLPDVIKVSTRSSEHFFSVF 235


>gi|38570103 TBC1 domain family, member 8B (with GRAM domain)
           isoform b [Homo sapiens]
          Length = 632

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 30/97 (30%), Positives = 57/97 (58%), Gaps = 4/97 (4%)

Query: 78  LPDTERLIADYACALQRD-ILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEK 136
           LP+ E+L+  Y+C+  +  +  QG LYLS N+L FYS +   E  + I+   ++ +  EK
Sbjct: 153 LPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDEVSKL--EK 210

Query: 137 TARLI-PNAIQIVTESEKFFFTSFGARDRSYLSIFRL 172
           T+ +I   +I + ++ E  +F+ F   +++YL + +L
Sbjct: 211 TSNVILTESIHVCSQGENHYFSMFLHINQTYLLMEQL 247


>gi|38570101 TBC1 domain family, member 8B (with GRAM domain)
           isoform a [Homo sapiens]
          Length = 1120

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 30/97 (30%), Positives = 57/97 (58%), Gaps = 4/97 (4%)

Query: 78  LPDTERLIADYACALQRD-ILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKEK 136
           LP+ E+L+  Y+C+  +  +  QG LYLS N+L FYS +   E  + I+   ++ +  EK
Sbjct: 153 LPEKEKLVTYYSCSYWKGRVPCQGWLYLSTNFLSFYSFLLGSEIKLIISWDEVSKL--EK 210

Query: 137 TARLI-PNAIQIVTESEKFFFTSFGARDRSYLSIFRL 172
           T+ +I   +I + ++ E  +F+ F   +++YL + +L
Sbjct: 211 TSNVILTESIHVCSQGENHYFSMFLHINQTYLLMEQL 247


>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
          Length = 1140

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 33/128 (25%), Positives = 64/128 (50%), Gaps = 12/128 (9%)

Query: 77  HLPDTERLIADYACALQRD-ILLQGRLYLSENWLCFYSNIFRWETTISIALKNITFMTKE 135
           + P+ E+L+  Y+C   +  +  QG LYLS N LCFYS  F     + + +  +     E
Sbjct: 152 NFPEAEKLVTYYSCCCWKGRVPRQGWLYLSINHLCFYS--FFLGKELKLVVPWVDIQKLE 209

Query: 136 KTARL-IPNAIQIVTESEKFFFTSFGARDRSY--------LSIFRLWQNVLLDKSLTRQE 186
           +T+ + + + I+I T++++  F+ F   D  +        +++ RL  N + D     QE
Sbjct: 210 RTSNVFLTDTIRITTQNKERDFSMFLNLDEVFKVMEQLADVTLRRLLDNEVFDLDPDLQE 269

Query: 187 FWQLLQQN 194
             Q+ +++
Sbjct: 270 PSQITKRD 277



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 30/101 (29%), Positives = 47/101 (46%), Gaps = 5/101 (4%)

Query: 70  EYRRQFTHLPDTERLIADYACALQRDIL---LQGRLYLSENWLCFYSNIFRWETTISIAL 126
           E+ R F  LP  E+L A   C+L          GR++ S++++CF S        I + L
Sbjct: 285 EFFRAFFRLPRKEKLHAVVDCSLWTPFSRCHTTGRMFASDSYICFASREDGC-CKIILPL 343

Query: 127 KNITFMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYL 167
           + +  + K +   L+P+ I IV+   K  F     RDR  L
Sbjct: 344 REVVSIEKMEDTSLLPHPI-IVSIRSKVAFQFIELRDRDSL 383


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 38.1 bits (87), Expect = 0.026
 Identities = 43/162 (26%), Positives = 71/162 (43%), Gaps = 18/162 (11%)

Query: 174 QNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEDVQPRSPGRSSL-----DD 228
           QN  + + L +Q+  +LL+Q    E    A E+E  S   ED      G +SL       
Sbjct: 133 QNSFIKQYLEKQQ--ELLRQRLERE-AREAAELEEASAESEDEMIHPEGVASLLPPDFQS 189

Query: 229 SGERDE-KLSKSISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLL-----P 282
           S ER E +LS+     S SIS     E  D +  K   G+  S   +Q + + L     P
Sbjct: 190 SLERPELELSRHSPRKSSSISE----EKGDSDDEKPRKGERRSSRVRQARAAKLSEGSQP 245

Query: 283 TLEKKLTRVPSKSLDLNKNEYLSLDKSSTSDSVDEENVPEKD 324
             E++    PS++L +  +  L  ++    +  +EE+  E++
Sbjct: 246 AEEEEDQETPSRNLRVRADRNLKTEEEEEEEEEEEEDDEEEE 287


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 37.7 bits (86), Expect = 0.034
 Identities = 35/136 (25%), Positives = 59/136 (43%), Gaps = 7/136 (5%)

Query: 184 RQEFWQLLQQNYGTELGLNAEEMEN---LSLSIEDVQPRSPGRSSLDDSGERDEKLSKSI 240
           R+E  +   +N G EL    EEM+     SL  +D     P  +  + +    E+L    
Sbjct: 171 REEQRKKAMENIG-ELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLD 229

Query: 241 SFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTRVPSKSLDLNK 300
           ++  E      E + F+  S KGG G E+      TK   + T +K +     K  +L +
Sbjct: 230 AYMEEV---KEEVKKFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELME 286

Query: 301 NEYLSLDKSSTSDSVD 316
           N+  +++ SS  + VD
Sbjct: 287 NDQDAMEYSSEEEEVD 302


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 37.4 bits (85), Expect = 0.045
 Identities = 25/94 (26%), Positives = 45/94 (47%)

Query: 231 ERDEKLSKSISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTR 290
           ++DEK  K  S T    S  ++ ES D +S   G  K+  ++EK+ KK      +KK  +
Sbjct: 419 QKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAK 478

Query: 291 VPSKSLDLNKNEYLSLDKSSTSDSVDEENVPEKD 324
             ++S ++  +  L  DK  + +    +   +KD
Sbjct: 479 KNAESTEMESDLELKKDKKHSKEKKGSKKDIKKD 512



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 10/93 (10%)

Query: 228 DSGERDEKLSKSISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKK 287
           D+ +  +K+ K++    +      +TES D  S   G  K+E ++ K+ KK L    +KK
Sbjct: 305 DAKKDSKKVKKNVKKDDKKKDVKKDTESTDAES---GDSKDERKDTKKDKKKLKKDDKKK 361

Query: 288 LTRVPSKSLDLN-------KNEYLSLDKSSTSD 313
            T+   +S D         +N+  +L K+S +D
Sbjct: 362 DTKKYPESTDTESGDAKDARNDSRNLKKASKND 394


>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
          Length = 2540

 Score = 36.6 bits (83), Expect = 0.076
 Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 15/114 (13%)

Query: 189  QLLQQNYGTEL-----------GLNAEEMENLSLSIEDV-QPRSPG---RSSLDDSGERD 233
            Q  Q NY T+L             N  +MEN   S+ ++ +P S      +S D     D
Sbjct: 1540 QTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVD 1599

Query: 234  EKLSKSISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKK 287
             K+        + ++R     +++  S  G   + ES++E++TK+   PT +KK
Sbjct: 1600 SKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKK 1653


>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
          Length = 2303

 Score = 36.6 bits (83), Expect = 0.076
 Identities = 29/114 (25%), Positives = 50/114 (43%), Gaps = 15/114 (13%)

Query: 189  QLLQQNYGTEL-----------GLNAEEMENLSLSIEDV-QPRSPG---RSSLDDSGERD 233
            Q  Q NY T+L             N  +MEN   S+ ++ +P S      +S D     D
Sbjct: 1321 QTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVD 1380

Query: 234  EKLSKSISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKK 287
             K+        + ++R     +++  S  G   + ES++E++TK+   PT +KK
Sbjct: 1381 SKIIVDKYVKDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKK 1434


>gi|191250773 spire homolog 1 isoform a [Homo sapiens]
          Length = 756

 Score = 36.6 bits (83), Expect = 0.076
 Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 3/82 (3%)

Query: 236 LSKSISFTSESISRVSETESF-DGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTRVPS- 293
           LS S SF    ++    T++  + +   GGL  +  +N   T + + P   KKL R P+ 
Sbjct: 401 LSMSYSFDLSDVTTPESTKNLVESSMVNGGLTSQTKENGLSTSQQV-PAQRKKLLRAPTL 459

Query: 294 KSLDLNKNEYLSLDKSSTSDSV 315
             LD +++E  +L KS++S SV
Sbjct: 460 AELDSSESEEETLHKSTSSSSV 481


>gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
          Length = 740

 Score = 35.0 bits (79), Expect = 0.22
 Identities = 47/204 (23%), Positives = 98/204 (48%), Gaps = 31/204 (15%)

Query: 172 LWQNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEDVQPRSPGR-SSLDDSG 230
           L+QN+ L +    Q +  +++ N+  E+ L + EMENL+++++  Q ++  + S L++  
Sbjct: 151 LYQNINLVEPRLIQPYEHVIK-NFIREIRLQSTEMENLAIAVKRAQDKAAMQLSELEE-- 207

Query: 231 ERDEKLSKSISFTSE-----------SISRVSETESFDGNSSKGGLGKEESQNEKQTKKS 279
           E D+++  +   T +            + R  ETE  D   +   L K E Q+++ ++K 
Sbjct: 208 EMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVGDLQVTIKKLRKLEEQSKRVSQKE 267

Query: 280 LLPTLEKKLTRVPSKSLDLNKN--------EYLSLDKSS-TSDSVDEENVPEKDLHGRLF 330
            +  L+K++  +  ++  + K+         +L  +  +  SD  D+    E+DL     
Sbjct: 268 DVAALKKQIYDLSMENQKVKKDLLEAQTNIAFLQSELDALKSDYADQSLNTERDLE---- 323

Query: 331 INRIF---HISADRMFELLFTSSR 351
           I R +     S +R  E+L T++R
Sbjct: 324 IIRAYTEDRNSLERQIEILQTANR 347


>gi|105990532 apolipoprotein B precursor [Homo sapiens]
          Length = 4563

 Score = 34.3 bits (77), Expect = 0.38
 Identities = 40/160 (25%), Positives = 69/160 (43%), Gaps = 25/160 (15%)

Query: 19   ATDLQEDVEENPSPTVEENNVVVKKQGPNLHNWSGDWSFWISSSTYKDRN--------EE 70
            A ++++ VE+    T+    V   K   N    S +  F+ +   Y +RN        E 
Sbjct: 2039 ALEMRDAVEKPQEFTI----VAFVKYDKNQDVHSINLPFFETLQEYFERNRQTIIVVLEN 2094

Query: 71   YRRQFTHLPDTERLIADYACALQRDILLQGRLYLSENWLCFYSNIFRWETTISIALKNIT 130
             +R   H+ + ++ +  Y  AL       G+L    N    Y N F WE  +S A + +T
Sbjct: 2095 VQRNLKHI-NIDQFVRKYRAAL-------GKLPQQAN---DYLNSFNWERQVSHAKEKLT 2143

Query: 131  FMTKEKTARLIPNAIQIVTESEKFFFTSFGARDRSYLSIF 170
             +TK+   R+  N IQI  +  K  F    ++ ++Y+  F
Sbjct: 2144 ALTKK--YRITENDIQIALDDAKINFNEKLSQLQTYMIQF 2181


>gi|16554564 caspase recruitment domain family, member 6 [Homo
           sapiens]
          Length = 1037

 Score = 34.3 bits (77), Expect = 0.38
 Identities = 50/214 (23%), Positives = 83/214 (38%), Gaps = 49/214 (22%)

Query: 182 LTRQEFWQLLQQNYGTELGLNAEEMEN--------LSLSIEDVQPRSPGRSSLDDSGERD 233
           L   EF++  + +Y  E  L+A + E         LS S+E V    P   +    G+R 
Sbjct: 142 LETSEFFRDKKTSY-RETALSARKNEKEYDTPEVTLSYSVEKVGCEVPATITYIKDGQRY 200

Query: 234 EKLSKSISF----------TSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPT 283
           E+L  S+            T E      E E +D     G  G+E+ +N + T+ S    
Sbjct: 201 EELDDSLYLGKEEYLGSVDTPEDAEATVEEEVYDDPEHVGYDGEEDFENSETTEFS---- 256

Query: 284 LEKKLTRVPSKSLDLNKNEYLSLDKSSTSDSVDEENVPEKDLHGRLFINRIFHISADRMF 343
                             E  S + S TS S++EE     +   ++F + +  ++ DR  
Sbjct: 257 -----------------GEEPSYEGSETSLSLEEEQEKSIEERKKVFKDVLLCLNMDRSR 299

Query: 344 ELLFTSSRFMQKFASSRNIIDVVSTPWTAELGGD 377
           ++L     F+++F+  R         WT E  GD
Sbjct: 300 KVL---PDFVKQFSLDR------GCKWTPESPGD 324


>gi|187828880 calcium channel, alpha 1A subunit isoform 3 [Homo
           sapiens]
          Length = 2261

 Score = 33.9 bits (76), Expect = 0.49
 Identities = 30/108 (27%), Positives = 59/108 (54%), Gaps = 12/108 (11%)

Query: 553 YNVTLIVVMSIFVLLLVL--LNVTLFLKLSKIEHAAQSFYRLRLQE--EKSLNLASDMVS 608
           Y + LI++ S F+L LVL  L+     +  ++E+  ++F +LR Q+  E+ LN   + +S
Sbjct: 339 YFIPLIIIGSFFMLNLVLGVLSGEFAKERERVEN-RRAFLKLRRQQQIERELNGYMEWIS 397

Query: 609 RAETI-----QKNKDQAHRLKGVLRDSIVMLEQLKSSLIMLQKTFDLL 651
           +AE +     + + +Q H   G LR + +  ++ K+ L+  ++  D L
Sbjct: 398 KAEEVILAEDETDGEQRHPFDGALRRTTI--KKSKTDLLNPEEAEDQL 443


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 33.9 bits (76), Expect = 0.49
 Identities = 56/286 (19%), Positives = 109/286 (38%), Gaps = 46/286 (16%)

Query: 228  DSGERDEKLSKSISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKK 287
            ++ +R  KL  ++    E + RVS  E             EE  N K   K  +P  E +
Sbjct: 987  ENEQRKRKLQAALINRKELLQRVSRLE-------------EELANLKDESKKEIPLSETE 1033

Query: 288  LTRVPSKSLDLNKNEYLSLDKSSTSDSVDEENVPEK---------DLHGRLFINRIFHIS 338
               V     +   +E     K    +   ++ + EK         DL  +L     F   
Sbjct: 1034 RGEVEEDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLAAEEQFQAL 1093

Query: 339  ADRMFELLFTSSR----FMQKFASSRNIIDVVSTPWTAELGGDQLRTMTYTIVLNSPLTG 394
              +M + L   +        + + ++ II  + T  T    GD +  +  T+V++ P TG
Sbjct: 1094 VKQMNQTLQDKTNQIDLLQAEISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTG 1153

Query: 395  KC---TAATEKQTLYKESREARFYLVDSEVLTHDVPYHDYFYTVNRYCIIRSSKQKCRLR 451
                     E++ L  E  + +      E LT            +R  I++ +++K R  
Sbjct: 1154 SSEHWKPELEEKILALEKEKEQLQKKLQEALT------------SRKAILKKAQEKER-H 1200

Query: 452  VSTDLKYRKQPWGLVKSLIEKNSW--SSLEDYFKQLESDLLIEESV 495
            +  +LK +K  +  ++   ++ S    ++ D  +QL+  + + ES+
Sbjct: 1201 LREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ--IQVRESI 1244



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 39/146 (26%), Positives = 62/146 (42%), Gaps = 17/146 (11%)

Query: 192 QQNYGTELGLNAEEMENLSLSIEDVQPRSPGRSSLDD--SGERDEKLS--KSISFTSESI 247
           Q+ Y   L   A+E+ NL+  IE+ +  +   SS     S ERD+ LS  K +S  +E  
Sbjct: 704 QEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELR 763

Query: 248 SRVSETESFDGNSSKGGLGKEESQN----EKQTKKSLLPTLEKKLTRVPSKSLDLNKNEY 303
           ++V + E          L + E Q     E QT    L T +     + +KS D+ K E 
Sbjct: 764 AQVKQLEM--------NLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDV-KIEV 814

Query: 304 LSLDKSSTSDSVDEENVPEKDLHGRL 329
           L  +         E++   + L  +L
Sbjct: 815 LQNELDDVQLQFSEQSTLIRSLQSQL 840


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 33.5 bits (75), Expect = 0.64
 Identities = 41/199 (20%), Positives = 90/199 (45%), Gaps = 29/199 (14%)

Query: 465 LVKSLIEKNSWSSLEDYFKQLESDLLIEESVLNQAIEDPGKLTGLRRRRRTFNRTAETVP 524
           L K L +K+    LED  K+LE +  + E +  +  E   + + LRR  +   +  E + 
Sbjct: 120 LEKQLEQKDR--ELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLC 177

Query: 525 KLSSQHSSGDVGLGAKGDITGKKKEMENYNVTLIVVM---SIFVLLLVLLNVTLFLKLSK 581
           +                DI   +K++++   TL+      S +   L   N  L   L +
Sbjct: 178 Q----------------DIIDYQKQIDSQKETLLSRRGEDSDYRSQLSKKNYELIQYLDE 221

Query: 582 IEHAAQSFYRLRLQEEKSLNLASDMVSRAETIQKNKDQAHRLKGVLRDSIVMLEQLKSS- 640
           I+   ++  ++ +Q ++   +  ++    + ++K  D+ +R+K ++  +  +++QLK   
Sbjct: 222 IQTLTEANEKIEVQNQE---MRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKKEN 278

Query: 641 ---LIMLQKTFDLL-NKNK 655
               + +Q+  DLL +KN+
Sbjct: 279 DHYQLQVQELTDLLKSKNE 297


>gi|16262452 cingulin [Homo sapiens]
          Length = 1203

 Score = 33.5 bits (75), Expect = 0.64
 Identities = 39/141 (27%), Positives = 58/141 (41%), Gaps = 13/141 (9%)

Query: 174  QNVLLDKSLTRQEFWQLLQQNYGTELGLNAEEMENLSLSIEDVQPRSPGRSSLDDSGERD 233
            QN LL + L  +E  + + Q+   +L    +E   LS+ IED   R       D    R 
Sbjct: 1053 QNQLLQERLQAEEREKTVLQSTNRKLERKVKE---LSIQIED--ERQHVNDQKDQLSLRV 1107

Query: 234  EKLSKSISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTRVPS 293
            + L + +    E I R+      DG   K     EE     +  ++ + +LEK   R  S
Sbjct: 1108 KALKRQVDEAEEEIERL------DGLRKKAQREVEEQHEVNEQLQARIKSLEKDSWRKAS 1161

Query: 294  KSL--DLNKNEYLSLDKSSTS 312
            +S      KNE LS D+   S
Sbjct: 1162 RSAAESALKNEGLSSDEEFDS 1182


>gi|8923106 zinc finger, CCHC domain containing 10 [Homo sapiens]
          Length = 170

 Score = 33.5 bits (75), Expect = 0.64
 Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 1/93 (1%)

Query: 231 ERDEKLSKSISFTSESISRVSETESFDGNSSKGGLGKEESQNEKQTKKSLLPTLEKKLTR 290
           ER  K  +S S TS S S  S++ + D +S         S  +  T +S   +     + 
Sbjct: 75  ERKAKKKRSKSVTSSSSSS-SDSSASDSSSESEETSTSSSSEDSDTDESSSSSSSSASST 133

Query: 291 VPSKSLDLNKNEYLSLDKSSTSDSVDEENVPEK 323
             S S D + +   S   S+++DS  ++  P+K
Sbjct: 134 TSSSSSDSDSDSSSSSSSSTSTDSSSDDEPPKK 166


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,190,171
Number of Sequences: 37866
Number of extensions: 928337
Number of successful extensions: 3849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 3725
Number of HSP's gapped (non-prelim): 185
length of query: 662
length of database: 18,247,518
effective HSP length: 109
effective length of query: 553
effective length of database: 14,120,124
effective search space: 7808428572
effective search space used: 7808428572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.