Guide to the Human Genome
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Search of human proteins with 187761381

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187761381 maestro isoform d [Homo sapiens]
         (262 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187761381 maestro isoform d [Homo sapiens]                         527   e-150
gi|187761375 maestro isoform a [Homo sapiens]                         432   e-121
gi|187761379 maestro isoform c [Homo sapiens]                         321   5e-88
gi|187761377 maestro isoform b [Homo sapiens]                         226   2e-59
gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]             142   2e-34
gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     100   2e-21
gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     100   2e-21
gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]     100   2e-21
gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5...    75   8e-14
gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]        75   8e-14
gi|148727311 hypothetical protein LOC389690 [Homo sapiens]             73   3e-13
gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo sapi...    34   0.15 
gi|4826730 FK506 binding protein 12-rapamycin associated protein...    32   0.43 
gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso...    31   1.3  
gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso...    31   1.3  
gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof...    31   1.3  
gi|118498337 HECT domain containing 1 [Homo sapiens]                   30   1.6  
gi|157743280 parahox cluster neighbor [Homo sapiens]                   30   1.6  
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]              30   2.8  
gi|13376768 elongation factor RNA polymerase II-like 3 [Homo sap...    30   2.8  
gi|23510381 transportin 1 isoform 2 [Homo sapiens]                     29   3.6  
gi|133925811 transportin 1 isoform 1 [Homo sapiens]                    29   3.6  
gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens]    29   4.8  
gi|144226251 chitinase 3-like 1 [Homo sapiens]                         28   6.2  
gi|239750109 PREDICTED: similar to unc-93 homolog B1 (C. elegans...    28   6.2  
gi|239744415 PREDICTED: similar to unc-93 homolog B1 (C. elegans...    28   6.2  
gi|7706575 transmembrane 7 superfamily member 3 [Homo sapiens]         28   6.2  
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]    28   6.2  
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]    28   6.2  
gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]                       28   8.1  

>gi|187761381 maestro isoform d [Homo sapiens]
          Length = 262

 Score =  527 bits (1357), Expect = e-150
 Identities = 262/262 (100%), Positives = 262/262 (100%)

Query: 1   MAWGSKGIQGWENLAESSHLATTRESSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPL 60
           MAWGSKGIQGWENLAESSHLATTRESSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPL
Sbjct: 1   MAWGSKGIQGWENLAESSHLATTRESSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPL 60

Query: 61  KNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEV 120
           KNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEV
Sbjct: 61  KNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEV 120

Query: 121 IHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRK 180
           IHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRK
Sbjct: 121 IHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRK 180

Query: 181 WKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKEEYSFQSEEDQRNTK 240
           WKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKEEYSFQSEEDQRNTK
Sbjct: 181 WKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKEEYSFQSEEDQRNTK 240

Query: 241 LYQQLSHYHPEILQFFYANKIL 262
           LYQQLSHYHPEILQFFYANKIL
Sbjct: 241 LYQQLSHYHPEILQFFYANKIL 262


>gi|187761375 maestro isoform a [Homo sapiens]
          Length = 248

 Score =  432 bits (1111), Expect = e-121
 Identities = 215/216 (99%), Positives = 216/216 (100%)

Query: 47  QVSWKLRFQKREPLKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLD 106
           +VSWKLRFQKREPLKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLD
Sbjct: 33  KVSWKLRFQKREPLKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLD 92

Query: 107 LLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSA 166
           LLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSA
Sbjct: 93  LLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSA 152

Query: 167 FVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKE 226
           FVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKE
Sbjct: 153 FVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKE 212

Query: 227 EYSFQSEEDQRNTKLYQQLSHYHPEILQFFYANKIL 262
           EYSFQSEEDQRNTKLYQQLSHYHPEILQFFYANKIL
Sbjct: 213 EYSFQSEEDQRNTKLYQQLSHYHPEILQFFYANKIL 248


>gi|187761379 maestro isoform c [Homo sapiens]
          Length = 210

 Score =  321 bits (822), Expect = 5e-88
 Identities = 180/262 (68%), Positives = 186/262 (70%), Gaps = 52/262 (19%)

Query: 1   MAWGSKGIQGWENLAESSHLATTRESSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPL 60
           MAWGSKGIQGWENLAESSHLATTRESSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPL
Sbjct: 1   MAWGSKGIQGWENLAESSHLATTRESSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPL 60

Query: 61  KNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEV 120
           KNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEV
Sbjct: 61  KNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEV 120

Query: 121 IHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRK 180
           IHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDD       +    F   + +   K
Sbjct: 121 IHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDD-------ACKTTFQACSPYLKLK 173

Query: 181 WKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKEEYSFQSEEDQRNTK 240
            +  F S+  Q    L                  +Q  S Y                   
Sbjct: 174 EEYSFQSEEDQRNTKL------------------YQQLSHY------------------- 196

Query: 241 LYQQLSHYHPEILQFFYANKIL 262
                   HPEILQFFYANKIL
Sbjct: 197 --------HPEILQFFYANKIL 210


>gi|187761377 maestro isoform b [Homo sapiens]
          Length = 196

 Score =  226 bits (576), Expect = 2e-59
 Identities = 133/216 (61%), Positives = 140/216 (64%), Gaps = 52/216 (24%)

Query: 47  QVSWKLRFQKREPLKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLD 106
           +VSWKLRFQKREPLKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLD
Sbjct: 33  KVSWKLRFQKREPLKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLD 92

Query: 107 LLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSA 166
           LLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDD       + 
Sbjct: 93  LLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDD-------AC 145

Query: 167 FVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKE 226
              F   + +   K +  F S+  Q    L                  +Q  S Y     
Sbjct: 146 KTTFQACSPYLKLKEEYSFQSEEDQRNTKL------------------YQQLSHY----- 182

Query: 227 EYSFQSEEDQRNTKLYQQLSHYHPEILQFFYANKIL 262
                                 HPEILQFFYANKIL
Sbjct: 183 ----------------------HPEILQFFYANKIL 196


>gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
          Length = 1585

 Score =  142 bits (359), Expect = 2e-34
 Identities = 75/203 (36%), Positives = 118/203 (58%), Gaps = 5/203 (2%)

Query: 26   SSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPLKNVFFILAERARDPSAKKRHMAMRN 85
            +S  E+   +G++  S L +  + WK        L+NV  ++ + A D +A  R MA+R 
Sbjct: 1272 TSSSENYRITGAAFFSELMKEPILWK-----HGNLRNVLILMDQSAWDSNATLRQMAIRG 1326

Query: 86   LGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFI 145
            LG  A  AP KV+K+K+++L+ ++ GLY     EV+ ES+K L  +L  +  + +  +F 
Sbjct: 1327 LGNTASGAPHKVKKHKQLMLESIIRGLYHLARTEVVCESLKALKKILELLTDRDVSFYFK 1386

Query: 146  DITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQDRNP 205
            +I LQTRT  +DE D +R +A  LF  LA   GR+WK FF  ++K++  S L+HL D NP
Sbjct: 1387 EIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNP 1446

Query: 206  QVAKACKTTFQACSPYLKLKEEY 228
            ++  AC+     C P+L L+E Y
Sbjct: 1447 KIGVACRDVLMVCIPFLGLQELY 1469


>gi|239753442 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1723

 Score =  100 bits (248), Expect = 2e-21
 Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 2/164 (1%)

Query: 57   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 114
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 1420 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1479

Query: 115  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLA 174
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+E++ LR  AF+LFG+LA
Sbjct: 1480 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLA 1539

Query: 175  AFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQAC 218
               G   K FF  +VK+    L++H QD     A+AC  T   C
Sbjct: 1540 RVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQC 1583


>gi|239748007 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1706

 Score =  100 bits (248), Expect = 2e-21
 Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 2/164 (1%)

Query: 57   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 114
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 1412 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1471

Query: 115  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLA 174
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+E++ LR  AF+LFG+LA
Sbjct: 1472 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLA 1531

Query: 175  AFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQAC 218
               G   K FF  +VK+    L++H QD     A+AC  T   C
Sbjct: 1532 RVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQC 1575


>gi|239741905 PREDICTED: HEAT repeat containing 7B1 [Homo sapiens]
          Length = 1710

 Score =  100 bits (248), Expect = 2e-21
 Identities = 58/164 (35%), Positives = 92/164 (56%), Gaps = 2/164 (1%)

Query: 57   REPLKNVFFILAERARDPSAKK--RHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 114
            +E L     +L E+  D    +  R +++R LG MA  AP KV++Y+K++L+  +  L +
Sbjct: 1416 QEKLLKPAALLLEKGADQEEDEALRVLSLRALGNMALGAPKKVKQYRKVLLEKCLGPLRE 1475

Query: 115  PVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLA 174
            PV+  V  E M+ LT +L +++   +GS F  ++ Q R   D+E++ LR  AF+LFG+LA
Sbjct: 1476 PVSNSVTAEGMEALTKILAELREGDVGSSFDAMSEQCRIFFDNESELLRLKAFILFGKLA 1535

Query: 175  AFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQAC 218
               G   K FF  +VK+    L++H QD     A+AC  T   C
Sbjct: 1536 RVVGMSKKHFFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQC 1579


>gi|113420243 PREDICTED: hypothetical protein LOC377711 isoform 5
            [Homo sapiens]
          Length = 1218

 Score = 74.7 bits (182), Expect = 8e-14
 Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 11/198 (5%)

Query: 67   LAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLE--VIHES 124
            LA R +D  A  R + +R L  +A   PDKVR +   +L  ++ GL D  N    V  E+
Sbjct: 945  LAARQKDTCASVRRLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPVALEA 1004

Query: 125  MKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRKWKKF 184
            M  L  ++  ++   L S  + + ++ R   D E    R ++  LFG L        +  
Sbjct: 1005 MLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDV 1064

Query: 185  FTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKEEYSFQSEEDQRNTKLY-- 242
            F  QV      LL+HLQD    VA AC+   + C P L  +E  +   +  Q    L+  
Sbjct: 1065 FLDQVVGGLAPLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFG 1124

Query: 243  -------QQLSHYHPEIL 253
                   + L H+ P++L
Sbjct: 1125 EFLNTTCKHLMHHFPDLL 1142


>gi|150010654 HEAT repeat containing 7A isoform 1 [Homo sapiens]
          Length = 1641

 Score = 74.7 bits (182), Expect = 8e-14
 Identities = 56/198 (28%), Positives = 87/198 (43%), Gaps = 11/198 (5%)

Query: 67   LAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLE--VIHES 124
            LA R +D  A  R + +R L  +A   PDKVR +   +L  ++ GL D  N    V  E+
Sbjct: 1368 LAARQKDTCASVRRLVLRGLANLASGCPDKVRTHGPQLLTAMIGGLDDGDNPHSPVALEA 1427

Query: 125  MKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAGRKWKKF 184
            M  L  ++  ++   L S  + + ++ R   D E    R ++  LFG L        +  
Sbjct: 1428 MLGLARLVHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDV 1487

Query: 185  FTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKEEYSFQSEEDQRNTKLY-- 242
            F  QV      LL+HLQD    VA AC+   + C P L  +E  +   +  Q    L+  
Sbjct: 1488 FLDQVVGGLAPLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFQKHLQEGRALHFG 1547

Query: 243  -------QQLSHYHPEIL 253
                   + L H+ P++L
Sbjct: 1548 EFLNTTCKHLMHHFPDLL 1565


>gi|148727311 hypothetical protein LOC389690 [Homo sapiens]
          Length = 1318

 Score = 72.8 bits (177), Expect = 3e-13
 Identities = 50/165 (30%), Positives = 85/165 (51%), Gaps = 3/165 (1%)

Query: 59   PLKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNL 118
            P +    +LA+   DPS + R ++++ L  + +  PDK    +  +  LL  G +   + 
Sbjct: 1038 PKQAALTVLAQGLHDPSPEVRVLSLQGLSNILFH-PDKGSLLQGQLRPLLD-GFFQSSD- 1094

Query: 119  EVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYSAFVLFGQLAAFAG 178
            +VI   M T++  L ++  +G GS  + + + TR+  +DE D +R +A  LFG L A   
Sbjct: 1095 QVIVCIMGTVSDTLHRLGAQGTGSQSLGVAISTRSFFNDERDGIRAAAMALFGDLVAAMA 1154

Query: 179  RKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLK 223
             +      +QV Q+   LL+HL+D+ P VA   K TF  C+  L+
Sbjct: 1155 DRELSGLRTQVHQSMVPLLLHLKDQCPAVATQAKFTFYRCAVLLR 1199


>gi|194595501 hypothetical protein LOC140699 isoform 1 [Homo
           sapiens]
          Length = 1052

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 26/86 (30%), Positives = 37/86 (43%), Gaps = 5/86 (5%)

Query: 144 FIDITLQTRTLL----DDENDSLRYSAFVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIH 199
           F  +    RTL     D  +D  R+S   LFG          KK   +QV  +   LL++
Sbjct: 839 FTTLAAMMRTLFSLFGDVRSDVHRFSV-TLFGAAIKSVKNPDKKSIENQVLDSLVPLLLY 897

Query: 200 LQDRNPQVAKACKTTFQACSPYLKLK 225
            QD N  VA+  +     C+ +LK K
Sbjct: 898 SQDENDAVAEESRQVLTICAQFLKWK 923


>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
           [Homo sapiens]
          Length = 2549

 Score = 32.3 bits (72), Expect = 0.43
 Identities = 38/126 (30%), Positives = 52/126 (41%), Gaps = 13/126 (10%)

Query: 61  KNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDP---VN 117
           K +  IL E       + +  + R LG +   AP  +R Y + +L  L+  L DP    N
Sbjct: 732 KMLIQILTELEHSGIGRIKEQSARMLGHLVSNAPRLIRPYMEPILKALILKLKDPDPDPN 791

Query: 118 LEVIHESMKT---LTVVLGKIQGKGLGSFFIDI--TLQTRTLLDDENDSLRYSAFVLFGQ 172
             VI+  + T   L  V G    K +   FI I   LQ  +LL     + R  A    GQ
Sbjct: 792 PGVINNVLATIGELAQVSGLEMRKWVDELFIIIMDMLQDSSLL-----AKRQVALWTLGQ 846

Query: 173 LAAFAG 178
           L A  G
Sbjct: 847 LVASTG 852


>gi|209969838 transportin 2 (importin 3, karyopherin beta 2b)
           isoform 1 [Homo sapiens]
          Length = 897

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 60  LKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLV--YGLYDPVN 117
           LK +   L +R  D + + +  A     T+  EA  ++  Y   +LD LV  +G Y   N
Sbjct: 475 LKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKN 534

Query: 118 LEVIHESMKTLTVVLG 133
           L ++++++ TL   +G
Sbjct: 535 LLILYDAIGTLADSVG 550


>gi|209969836 transportin 2 (importin 3, karyopherin beta 2b)
           isoform 3 [Homo sapiens]
          Length = 887

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 60  LKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLV--YGLYDPVN 117
           LK +   L +R  D + + +  A     T+  EA  ++  Y   +LD LV  +G Y   N
Sbjct: 475 LKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKN 534

Query: 118 LEVIHESMKTLTVVLG 133
           L ++++++ TL   +G
Sbjct: 535 LLILYDAIGTLADSVG 550


>gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform
           2 [Homo sapiens]
          Length = 887

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 2/76 (2%)

Query: 60  LKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLV--YGLYDPVN 117
           LK +   L +R  D + + +  A     T+  EA  ++  Y   +LD LV  +G Y   N
Sbjct: 475 LKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKN 534

Query: 118 LEVIHESMKTLTVVLG 133
           L ++++++ TL   +G
Sbjct: 535 LLILYDAIGTLADSVG 550


>gi|118498337 HECT domain containing 1 [Homo sapiens]
          Length = 2610

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 16/43 (37%), Positives = 19/43 (44%)

Query: 5   SKGIQGWENLAESSHLATTRESSPPESGTGSGSSRGSRLQEPQ 47
           S G  GW        LAT   S  PE G+ S  SR   L++ Q
Sbjct: 687 SNGSNGWFRFILDGKLATMYSSGSPEGGSDSSESRSEFLEKLQ 729


>gi|157743280 parahox cluster neighbor [Homo sapiens]
          Length = 173

 Score = 30.4 bits (67), Expect = 1.6
 Identities = 27/84 (32%), Positives = 36/84 (42%), Gaps = 10/84 (11%)

Query: 23  TRESSPPESGTGS---GSSRGSRLQEPQVSWKLRFQKREPLKNVFFILAERARDPSAKKR 79
           T ES   +SG G    G+    RL E    ++ RF          F+LA R  D +A  R
Sbjct: 81  TAESQREQSGAGLRSLGADERLRLAELNAQYRARF-------GFPFVLAARFSDRTAVPR 133

Query: 80  HMAMRNLGTMAYEAPDKVRKYKKI 103
            +A R L   A E    + + KKI
Sbjct: 134 ELARRLLCPSAQELRTALGEVKKI 157


>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
          Length = 587

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 24/88 (27%), Positives = 35/88 (39%)

Query: 2   AWGSKGIQGWENLAESSHLATTRESSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPLK 61
           A+G  G+QG+E L +SS   T +E      G G G  +       +   K   Q +    
Sbjct: 123 AFGPDGVQGFEALLKSSACFTLQELKLNNCGMGIGGGKILAAALTECHRKSSAQGKPLAL 182

Query: 62  NVFFILAERARDPSAKKRHMAMRNLGTM 89
            VF     R  +  A     A R +GT+
Sbjct: 183 KVFVAGRNRLENDGATALAEAFRVIGTL 210


>gi|13376768 elongation factor RNA polymerase II-like 3 [Homo
           sapiens]
          Length = 397

 Score = 29.6 bits (65), Expect = 2.8
 Identities = 15/40 (37%), Positives = 23/40 (57%)

Query: 221 YLKLKEEYSFQSEEDQRNTKLYQQLSHYHPEILQFFYANK 260
           Y K +++Y    EE +R   L+Q+LSH    IL+F   N+
Sbjct: 356 YKKFRKQYPSYREEKRRCEYLHQKLSHIKGLILEFEEKNR 395


>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
          Length = 890

 Score = 29.3 bits (64), Expect = 3.6
 Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 60  LKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGL--YDPVN 117
           LK +   L +R  D + + +  A     T+  EA  ++  Y   +LD LV+    Y   N
Sbjct: 478 LKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKN 537

Query: 118 LEVIHESMKTLTVVLG 133
           L ++++++ TL   +G
Sbjct: 538 LLILYDAIGTLADSVG 553


>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
          Length = 898

 Score = 29.3 bits (64), Expect = 3.6
 Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 60  LKNVFFILAERARDPSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGL--YDPVN 117
           LK +   L +R  D + + +  A     T+  EA  ++  Y   +LD LV+    Y   N
Sbjct: 486 LKPLMTELLKRILDSNKRVQEAACSAFATLEEEACTELVPYLAYILDTLVFAFSKYQHKN 545

Query: 118 LEVIHESMKTLTVVLG 133
           L ++++++ TL   +G
Sbjct: 546 LLILYDAIGTLADSVG 561


>gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens]
          Length = 919

 Score = 28.9 bits (63), Expect = 4.8
 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 1/41 (2%)

Query: 74  PSAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYD 114
           P  +K  +   N+  M Y AP K R++   VLD   +G YD
Sbjct: 106 PDGRKFVVTKGNIAQM-YHAPGKKREFNAFVLDKTYFGPYD 145


>gi|144226251 chitinase 3-like 1 [Homo sapiens]
          Length = 383

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 7/132 (5%)

Query: 106 DLLVYGLYDPVNLEVIHESMKTLTVVLGKIQGKGLGSFFIDITLQTRTLLDDENDSLRYS 165
           D+ +YG+ +   L+  + ++KTL  V G   G    S     T   RT +      LR  
Sbjct: 73  DVTLYGMLN--TLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQSRRTFIKSVPPFLRTH 130

Query: 166 AFVLFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQV-----AKACKTTFQACSP 220
            F        + GR+ K+ FT+ +K+ +   +   Q    Q+       A K T  +   
Sbjct: 131 GFDGLDLAWLYPGRRDKQHFTTLIKEMKAEFIKEAQPGKKQLLLSAALSAGKVTIDSSYD 190

Query: 221 YLKLKEEYSFQS 232
             K+ +   F S
Sbjct: 191 IAKISQHLDFIS 202


>gi|239750109 PREDICTED: similar to unc-93 homolog B1 (C. elegans)
           [Homo sapiens]
          Length = 529

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 15/30 (50%), Positives = 19/30 (63%), Gaps = 4/30 (13%)

Query: 9   QGWENLAESSHLATTRESSPPESGTGSGSS 38
           QG+EN AE+    +TR    P +G GSGSS
Sbjct: 233 QGFENTAETLRALSTR----PSAGAGSGSS 258


>gi|239744415 PREDICTED: similar to unc-93 homolog B1 (C. elegans)
           [Homo sapiens]
          Length = 503

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 15/30 (50%), Positives = 19/30 (63%), Gaps = 4/30 (13%)

Query: 9   QGWENLAESSHLATTRESSPPESGTGSGSS 38
           QG+EN AE+    +TR    P +G GSGSS
Sbjct: 207 QGFENTAETLRALSTR----PSAGAGSGSS 232


>gi|7706575 transmembrane 7 superfamily member 3 [Homo sapiens]
          Length = 570

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 15/49 (30%), Positives = 26/49 (53%)

Query: 26  SSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPLKNVFFILAERARDP 74
           S+  E+GT SG     R ++   +W L     +P++N+  +L+   RDP
Sbjct: 86  SNSSETGTASGLVFILRPEQSTCTWYLGTSGIQPVQNMAILLSYSERDP 134


>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
          Length = 971

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 37/190 (19%)

Query: 76  AKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLE---------------V 120
           A K HMA+  + + A      +R  KK+ +DL      D +NLE               V
Sbjct: 367 AWKHHMAIEAVHSNA------IRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEV 420

Query: 121 IHESMKTLTVVLGKIQG------KGLGSF------FIDITLQTRTLLDDENDSLRYSAFV 168
           + + + T    +G +Q       +GLGS         D   + +  LD   DSL+ +   
Sbjct: 421 LEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDA 480

Query: 169 LFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKEEY 228
           L          + +   T    +  + L +     + ++ K  +   Q CS   KL+EE 
Sbjct: 481 LLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI-KWTENLRQECS---KLREEL 536

Query: 229 SFQSEEDQRN 238
             Q EED+++
Sbjct: 537 RLQHEEDKKS 546


>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
          Length = 1140

 Score = 28.5 bits (62), Expect = 6.2
 Identities = 44/190 (23%), Positives = 74/190 (38%), Gaps = 37/190 (19%)

Query: 76  AKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGLYDPVNLE---------------V 120
           A K HMA+  + + A      +R  KK+ +DL      D +NLE               V
Sbjct: 487 AWKHHMAIEAVHSNA------IRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEV 540

Query: 121 IHESMKTLTVVLGKIQG------KGLGSF------FIDITLQTRTLLDDENDSLRYSAFV 168
           + + + T    +G +Q       +GLGS         D   + +  LD   DSL+ +   
Sbjct: 541 LEDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIASLQDSQERLQNELDLTKDSLKETKDA 600

Query: 169 LFGQLAAFAGRKWKKFFTSQVKQTRDSLLIHLQDRNPQVAKACKTTFQACSPYLKLKEEY 228
           L          + +   T    +  + L +     + ++ K  +   Q CS   KL+EE 
Sbjct: 601 LLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI-KWTENLRQECS---KLREEL 656

Query: 229 SFQSEEDQRN 238
             Q EED+++
Sbjct: 657 RLQHEEDKKS 666


>gi|7669528 neuregulin 2 isoform 2 [Homo sapiens]
          Length = 844

 Score = 28.1 bits (61), Expect = 8.1
 Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 16/127 (12%)

Query: 15  AESSHLATTRESSPPESGTGSGSSRGSRLQEPQVSWKLRFQKREPLKNVFFILAERARDP 74
           ++SS  ++ R SS   S + SGSS  S      +S      +  P +        + R P
Sbjct: 23  SDSSSSSSERSSSSSSSSSESGSSSRSSSNNSSISRPAAPPEPRPQQQ------PQPRSP 76

Query: 75  SAKKRHMAMRNLGTMAYEAPDKVRKYKKIVLDLLVYGL----YDPVNLEVIHESMKTLTV 130
           +A++     R        A   +R+       +L++G+    Y P    V  ++ K   V
Sbjct: 77  AARRAAARSRAA------AAGGMRRDPAPGFSMLLFGVSLACYSPSLKSVQDQAYKAPVV 130

Query: 131 VLGKIQG 137
           V GK+QG
Sbjct: 131 VEGKVQG 137


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,741,777
Number of Sequences: 37866
Number of extensions: 405800
Number of successful extensions: 1478
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1451
Number of HSP's gapped (non-prelim): 39
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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