Search of human proteins with 18765731

Search of human proteins with 18765731

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18765731 synaptosomal-associated protein 23 isoform SNAP23B
[Homo sapiens]
         (158 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18765731 synaptosomal-associated protein 23 isoform SNAP23B [...   312   7e-86
gi|18765729 synaptosomal-associated protein 23 isoform SNAP23A [...   281   1e-76
gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B [...   193   6e-50
gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A [...   185   2e-47
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom...    42   3e-04
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom...    42   3e-04
gi|4759154 synaptosomal-associated protein 29 [Homo sapiens]           36   0.016
gi|224465202 synaptosomal-associated protein, 47kDa [Homo sapiens]     36   0.016
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         35   0.027
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         35   0.027
gi|33188443 microfilament and actin filament cross-linker protei...    34   0.045
gi|33188445 microfilament and actin filament cross-linker protei...    34   0.045
gi|169178850 PREDICTED: similar to coiled-coil domain containing...    33   0.10 
gi|197313728 pleckstrin homology-like domain, family B, member 2...    33   0.10 
gi|21955172 pleckstrin homology-like domain, family B, member 2 ...    33   0.10 
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]                    33   0.13 
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]                    33   0.13 
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]                    33   0.13 
gi|226493203 coiled-coil domain containing 76 [Homo sapiens]           33   0.13 
gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo sa...    32   0.17 
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]        32   0.17 
gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]            32   0.23 
gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo...    32   0.23 
gi|4503593 epidermal growth factor receptor pathway substrate 15...    32   0.29 
gi|5032131 syntaxin 6 [Homo sapiens]                                   32   0.29 
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    31   0.50 
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo...    31   0.50 
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo...    31   0.50 
gi|4759188 syntaxin 8 [Homo sapiens]                                   31   0.50 
gi|5454166 vesicle transport through interaction with t-SNAREs 1...    31   0.50 

>gi|18765731 synaptosomal-associated protein 23 isoform SNAP23B
           [Homo sapiens]
          Length = 158

 Score =  312 bits (800), Expect = 7e-86
 Identities = 158/158 (100%), Positives = 158/158 (100%)

Query: 1   MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLD 60
           MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLD
Sbjct: 1   MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLD 60

Query: 61  QINKDMRETEKTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDMALNI 120
           QINKDMRETEKTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDMALNI
Sbjct: 61  QINKDMRETEKTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDMALNI 120

Query: 121 GNEIDAQNPQIKRITDKADTNRDRIDIANARAKKLIDS 158
           GNEIDAQNPQIKRITDKADTNRDRIDIANARAKKLIDS
Sbjct: 121 GNEIDAQNPQIKRITDKADTNRDRIDIANARAKKLIDS 158


>gi|18765729 synaptosomal-associated protein 23 isoform SNAP23A
           [Homo sapiens]
          Length = 211

 Score =  281 bits (720), Expect = 1e-76
 Identities = 155/211 (73%), Positives = 155/211 (73%), Gaps = 53/211 (25%)

Query: 1   MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLD 60
           MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLD
Sbjct: 1   MDNLSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLD 60

Query: 61  QINKDMRETEKTLTELNKCCGLCVCPCNSITN---------------------------- 92
           QINKDMRETEKTLTELNKCCGLCVCPCN   N                            
Sbjct: 61  QINKDMRETEKTLTELNKCCGLCVCPCNRTKNFESGKAYKTTWGDGGENSPCNVVSKQPG 120

Query: 93  -------------------------DAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQ 127
                                    DAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQ
Sbjct: 121 PVTNGQLQQPTTGAASGGYIKRITNDAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQ 180

Query: 128 NPQIKRITDKADTNRDRIDIANARAKKLIDS 158
           NPQIKRITDKADTNRDRIDIANARAKKLIDS
Sbjct: 181 NPQIKRITDKADTNRDRIDIANARAKKLIDS 211


>gi|18765735 synaptosomal-associated protein 25 isoform SNAP25B
           [Homo sapiens]
          Length = 206

 Score =  193 bits (490), Expect = 6e-50
 Identities = 104/194 (53%), Positives = 126/194 (64%), Gaps = 42/194 (21%)

Query: 7   EEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDM 66
           EE+Q+RA Q+ DESLESTRR+L L  ES+DAGI+T+ MLDEQ EQL RIEEG+DQINKDM
Sbjct: 12  EEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLERIEEGMDQINKDM 71

Query: 67  RETEKTLTELNKCCGLCVCPCNS------------------------------------- 89
           +E EK LT+L K CGLCVCPCN                                      
Sbjct: 72  KEAEKNLTDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISG 131

Query: 90  -----ITNDAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDR 144
                +TNDARE+EM+ENL QV  I+GNL+ MAL++GNEID QN QI RI +KAD+N+ R
Sbjct: 132 GFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTR 191

Query: 145 IDIANARAKKLIDS 158
           ID AN RA K++ S
Sbjct: 192 IDEANQRATKMLGS 205


>gi|18765733 synaptosomal-associated protein 25 isoform SNAP25A
           [Homo sapiens]
          Length = 206

 Score =  185 bits (469), Expect = 2e-47
 Identities = 98/194 (50%), Positives = 125/194 (64%), Gaps = 42/194 (21%)

Query: 7   EEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDM 66
           EE+Q+RA Q+ DESLESTRR+L L  ES+DAGI+T+ MLDEQ EQL+R+EEG++ IN+DM
Sbjct: 12  EEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRVEEGMNHINQDM 71

Query: 67  RETEKTLTELNKCCGLCVCPCNS------------------------------------- 89
           +E EK L +L KCCGL +CPCN                                      
Sbjct: 72  KEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISG 131

Query: 90  -----ITNDAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDR 144
                +TNDARE+EM+ENL QV  I+GNL+ MAL++GNEID QN QI RI +KAD+N+ R
Sbjct: 132 GFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTR 191

Query: 145 IDIANARAKKLIDS 158
           ID AN RA K++ S
Sbjct: 192 IDEANQRATKMLGS 205


>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
           sapiens]
          Length = 1133

 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 34/159 (21%), Positives = 73/159 (45%), Gaps = 23/159 (14%)

Query: 7   EEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQ----KEQLNRIEEGLDQI 62
           E+      ++ ++  ES RRILG  + ++ +  +TI  L+E+    KE + + +E +  +
Sbjct: 137 EKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLL 196

Query: 63  NKDMRETEKTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDMALNIGN 122
            ++    +K + +  K            + + +E E E+ +T +   L  LK  AL + +
Sbjct: 197 EQECERLKKLIDQEIK------------SQEEKEQEKEKRVTTLKEELTKLKSFALMVVD 244

Query: 123 E-------IDAQNPQIKRITDKADTNRDRIDIANARAKK 154
           E       +  Q  +I+ +T  A     ++ +A AR ++
Sbjct: 245 EQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQE 283


>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
           sapiens]
          Length = 1135

 Score = 41.6 bits (96), Expect = 3e-04
 Identities = 34/159 (21%), Positives = 73/159 (45%), Gaps = 23/159 (14%)

Query: 7   EEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQ----KEQLNRIEEGLDQI 62
           E+      ++ ++  ES RRILG  + ++ +  +TI  L+E+    KE + + +E +  +
Sbjct: 137 EKPMNELDKVVEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLL 196

Query: 63  NKDMRETEKTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDMALNIGN 122
            ++    +K + +  K            + + +E E E+ +T +   L  LK  AL + +
Sbjct: 197 EQECERLKKLIDQEIK------------SQEEKEQEKEKRVTTLKEELTKLKSFALMVVD 244

Query: 123 E-------IDAQNPQIKRITDKADTNRDRIDIANARAKK 154
           E       +  Q  +I+ +T  A     ++ +A AR ++
Sbjct: 245 EQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQE 283


>gi|4759154 synaptosomal-associated protein 29 [Homo sapiens]
          Length = 258

 Score = 35.8 bits (81), Expect = 0.016
 Identities = 17/46 (36%), Positives = 28/46 (60%)

Query: 94  AREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKAD 139
           A   +++ NL ++   LG LKD+AL +  EI+ Q+  + R+T K D
Sbjct: 197 AYHQKIDSNLDELSMGLGRLKDIALGMQTEIEEQDDILDRLTTKVD 242



 Score = 29.3 bits (64), Expect = 1.5
 Identities = 16/63 (25%), Positives = 35/63 (55%), Gaps = 3/63 (4%)

Query: 14  HQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTL 73
           HQ  D +L+     LG     +D  +   T ++EQ + L+R+   +D+++ +++ TE+ +
Sbjct: 199 HQKIDSNLDELSMGLG---RLKDIALGMQTEIEEQDDILDRLTTKVDKLDVNIKSTERKV 255

Query: 74  TEL 76
            +L
Sbjct: 256 RQL 258


>gi|224465202 synaptosomal-associated protein, 47kDa [Homo sapiens]
          Length = 464

 Score = 35.8 bits (81), Expect = 0.016
 Identities = 21/63 (33%), Positives = 33/63 (52%), Gaps = 2/63 (3%)

Query: 16  ITDESLESTR--RILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTL 73
           + D S+  TR   + GL   SQ     T  +L  Q +QL+ +  GLD++  D+   ++ L
Sbjct: 154 VADASVPRTRGEELTGLMAGSQKRLEDTARVLHHQGQQLDSVMRGLDKMESDLEVADRLL 213

Query: 74  TEL 76
           TEL
Sbjct: 214 TEL 216


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 35.0 bits (79), Expect = 0.027
 Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 32/174 (18%)

Query: 6    SEEIQQRAHQITDESLESTRRI----------------LGLAIESQDAGI---------K 40
            +EE+QQ   Q+  +  EST R+                LGLAI+  DA           K
Sbjct: 2223 NEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGK 2282

Query: 41   TITMLDEQKEQLNRIEEGLDQINKDMRET--EKTLTELNKCCGLCVCPCNSITNDAR--E 96
               ++ E++ +++++ E + ++ + ++ T   K + E N+           + +D    +
Sbjct: 2283 FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVK 2342

Query: 97   DEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDRIDIANA 150
               EE + Q+  ++  L+    NIG +    +     ++++AD+ + ++D+  A
Sbjct: 2343 RNREEEIEQLNEVIEKLQQELANIGQK---TSMNAHSLSEEADSLKHQLDVVIA 2393


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 35.0 bits (79), Expect = 0.027
 Identities = 35/174 (20%), Positives = 77/174 (44%), Gaps = 32/174 (18%)

Query: 6    SEEIQQRAHQITDESLESTRRI----------------LGLAIESQDAGI---------K 40
            +EE+QQ   Q+  +  EST R+                LGLAI+  DA           K
Sbjct: 2215 NEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGK 2274

Query: 41   TITMLDEQKEQLNRIEEGLDQINKDMRET--EKTLTELNKCCGLCVCPCNSITNDAR--E 96
               ++ E++ +++++ E + ++ + ++ T   K + E N+           + +D    +
Sbjct: 2275 FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVK 2334

Query: 97   DEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDRIDIANA 150
               EE + Q+  ++  L+    NIG +    +     ++++AD+ + ++D+  A
Sbjct: 2335 RNREEEIEQLNEVIEKLQQELANIGQK---TSMNAHSLSEEADSLKHQLDVVIA 2385


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 34.3 bits (77), Expect = 0.045
 Identities = 32/161 (19%), Positives = 67/161 (41%), Gaps = 22/161 (13%)

Query: 6    SEEIQQRAHQITDESLESTR------------RILGLAIESQDAGIKTITMLDEQKEQLN 53
            ++++  R+ QI    ++ST+            R +G  +  Q A       + +Q E+ +
Sbjct: 3108 TDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEAVKQQLEETS 3167

Query: 54   RIEEGLDQINKDMRETEKTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNL 113
             I   L+Q++ +++E +    EL+   G              +DE+++ L  V   L  L
Sbjct: 3168 EIRSDLEQLDHEVKEAQTLCDELSVLIG----------EQYLKDELKKRLETVALPLQGL 3217

Query: 114  KDMALNIGNEIDAQNPQIKRITDKADTNRDRIDIANARAKK 154
            +D+A +  N + A     ++     D  R  +D   ++  K
Sbjct: 3218 EDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQQAK 3258


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 34.3 bits (77), Expect = 0.045
 Identities = 32/161 (19%), Positives = 67/161 (41%), Gaps = 22/161 (13%)

Query: 6    SEEIQQRAHQITDESLESTR------------RILGLAIESQDAGIKTITMLDEQKEQLN 53
            ++++  R+ QI    ++ST+            R +G  +  Q A       + +Q E+ +
Sbjct: 2606 TDKLNSRSSQIDQAIVKSTQYQELLQDLSEKVRAVGQRLSVQSAISTQPEAVKQQLEETS 2665

Query: 54   RIEEGLDQINKDMRETEKTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNL 113
             I   L+Q++ +++E +    EL+   G              +DE+++ L  V   L  L
Sbjct: 2666 EIRSDLEQLDHEVKEAQTLCDELSVLIG----------EQYLKDELKKRLETVALPLQGL 2715

Query: 114  KDMALNIGNEIDAQNPQIKRITDKADTNRDRIDIANARAKK 154
            +D+A +  N + A     ++     D  R  +D   ++  K
Sbjct: 2716 EDLAADRINRLQAALASTQQFQQMFDELRTWLDDKQSQQAK 2756


>gi|169178850 PREDICTED: similar to coiled-coil domain containing 29
           [Homo sapiens]
          Length = 197

 Score = 33.1 bits (74), Expect = 0.10
 Identities = 21/92 (22%), Positives = 45/92 (48%), Gaps = 14/92 (15%)

Query: 4   LSSEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNR--------- 54
           LS +++QQ   ++ +        IL L    +++ ++ ++ L E K +L+          
Sbjct: 67  LSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVE-LSKLQEYKSELDERAMQAVEKL 125

Query: 55  ----IEEGLDQINKDMRETEKTLTELNKCCGL 82
               ++  LD + + +RET++T+  L+ CC L
Sbjct: 126 KEIHLQMELDCVEQIIRETKRTVAVLDTCCHL 157


>gi|197313728 pleckstrin homology-like domain, family B, member 2
           isoform b [Homo sapiens]
          Length = 1237

 Score = 33.1 bits (74), Expect = 0.10
 Identities = 38/152 (25%), Positives = 64/152 (42%), Gaps = 27/152 (17%)

Query: 7   EEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRI---EEGLDQIN 63
           EE++Q+   I D+  ES R +           ++   +  EQK +   +   +E LD +N
Sbjct: 629 EELKQKIKDINDQMDESFREL----------DMECALLDGEQKSETTELMKEKEILDHLN 678

Query: 64  KDMRETEKTLT-ELNKCCGLCVCPCN--------SITNDAREDEMEENLTQVGSILGNLK 114
           + + E EK +  E  K   L               + +++R DE +ENLTQ   +L  + 
Sbjct: 679 RKIAELEKNIVGEKTKDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQ--QLLREVA 736

Query: 115 DMALNI---GNEIDAQNPQIKRITDKADTNRD 143
           +   NI     +I A   Q   I  +A   +D
Sbjct: 737 EYQRNIVSRKEKISALKKQANHIVQQAQREQD 768


>gi|21955172 pleckstrin homology-like domain, family B, member 2
           isoform c [Homo sapiens]
          Length = 1210

 Score = 33.1 bits (74), Expect = 0.10
 Identities = 38/152 (25%), Positives = 64/152 (42%), Gaps = 27/152 (17%)

Query: 7   EEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRI---EEGLDQIN 63
           EE++Q+   I D+  ES R +           ++   +  EQK +   +   +E LD +N
Sbjct: 602 EELKQKIKDINDQMDESFREL----------DMECALLDGEQKSETTELMKEKEILDHLN 651

Query: 64  KDMRETEKTLT-ELNKCCGLCVCPCN--------SITNDAREDEMEENLTQVGSILGNLK 114
           + + E EK +  E  K   L               + +++R DE +ENLTQ   +L  + 
Sbjct: 652 RKIAELEKNIVGEKTKDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQ--QLLREVA 709

Query: 115 DMALNI---GNEIDAQNPQIKRITDKADTNRD 143
           +   NI     +I A   Q   I  +A   +D
Sbjct: 710 EYQRNIVSRKEKISALKKQANHIVQQAQREQD 741


>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
          Length = 247

 Score = 32.7 bits (73), Expect = 0.13
 Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 12/150 (8%)

Query: 11  QRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETE 70
           + A +  DES    + I   A++ ++        L E K      +   +++ + +   E
Sbjct: 78  EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIE 137

Query: 71  KTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQ 130
             L    +   L    C+         E+EE L  V + L +L+  A     + D    +
Sbjct: 138 GDLERTEERAELAESKCS---------ELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188

Query: 131 IKRITDK---ADTNRDRIDIANARAKKLID 157
           IK +TDK   A+T  +  + + A+ +K ID
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTID 218


>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
          Length = 248

 Score = 32.7 bits (73), Expect = 0.13
 Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 12/150 (8%)

Query: 11  QRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETE 70
           + A +  DES    + I   A++ ++        L E K      +   +++ + +   E
Sbjct: 78  EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIE 137

Query: 71  KTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQ 130
             L    +   L    C+         E+EE L  V + L +L+  A     + D    +
Sbjct: 138 GDLERTEERAELAESKCS---------ELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 188

Query: 131 IKRITDK---ADTNRDRIDIANARAKKLID 157
           IK +TDK   A+T  +  + + A+ +K ID
Sbjct: 189 IKILTDKLKEAETRAEFAERSVAKLEKTID 218


>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
          Length = 285

 Score = 32.7 bits (73), Expect = 0.13
 Identities = 33/150 (22%), Positives = 61/150 (40%), Gaps = 12/150 (8%)

Query: 11  QRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETE 70
           + A +  DES    + I   A++ ++        L E K      +   +++ + +   E
Sbjct: 115 EEAEKAADESERGMKVIENRALKDEEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIE 174

Query: 71  KTLTELNKCCGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQ 130
             L    +   L    C+         E+EE L  V + L +L+  A     + D    +
Sbjct: 175 GDLERTEERAELAESKCS---------ELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEE 225

Query: 131 IKRITDK---ADTNRDRIDIANARAKKLID 157
           IK +TDK   A+T  +  + + A+ +K ID
Sbjct: 226 IKILTDKLKEAETRAEFAERSVAKLEKTID 255


>gi|226493203 coiled-coil domain containing 76 [Homo sapiens]
          Length = 481

 Score = 32.7 bits (73), Expect = 0.13
 Identities = 24/89 (26%), Positives = 47/89 (52%), Gaps = 2/89 (2%)

Query: 32  IESQDAGIKTITMLDEQKEQLNRI-EEGLDQINKDMRETEKTLTELNKCCGLCVCPCNSI 90
           I+  +AG++  T + EQ   ++ + EE L+++ K +R+  + L    K   +     +  
Sbjct: 91  IQDINAGLRDETEIPEQLVPISSLSEEQLEKLIKKLRKASEGLNSTLKDHIMSHPALHDA 150

Query: 91  TNDARE-DEMEENLTQVGSILGNLKDMAL 118
            ND +  D   ++L Q  SILGN++++ L
Sbjct: 151 LNDPKNGDSATKHLKQQASILGNIENLKL 179


>gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo
           sapiens]
          Length = 417

 Score = 32.3 bits (72), Expect = 0.17
 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 12/108 (11%)

Query: 6   SEEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEG-LDQINK 64
           +EE ++   +  +ES  ++R ++      +      +T+ +E  E+ N++EE  + Q  K
Sbjct: 297 TEEDEEEDEEEEEESFMTSREMIPERKNQEKESDDALTVNEETSEENNQMEESDVSQAEK 356

Query: 65  DMRETEKTLTELNKCCGLCVCPCNSITNDAREDE--MEENLTQVGSIL 110
           D+  +E +  E          P +S ++D RE E  +  N ++ G IL
Sbjct: 357 DLLHSEGSENE---------GPVSSSSSDCRETEELVGSNSSKTGEIL 395


>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
          Length = 818

 Score = 32.3 bits (72), Expect = 0.17
 Identities = 16/45 (35%), Positives = 25/45 (55%)

Query: 22  ESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDM 66
           + T +  GL+   Q AG K   + +E +E  NR+E   DQ++ DM
Sbjct: 157 QQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRDQLSADM 201


>gi|197927452 dynein, axonemal, heavy chain 1 [Homo sapiens]
          Length = 4265

 Score = 32.0 bits (71), Expect = 0.23
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 19/97 (19%)

Query: 19   ESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTLTELNK 78
            +++E  R+ L   +E+QD    T  +LDE K++L  +E+G+  +    RE      EL  
Sbjct: 3051 KAVEPKRQAL---LEAQDDLGVTQRILDEAKQRLREVEDGIATMQAKYRECITKKEELEL 3107

Query: 79   CCGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKD 115
             C  C                E+ L + G ++  L D
Sbjct: 3108 KCEQC----------------EQRLGRAGKLINGLSD 3128


>gi|109715852 chromosome 6 open reading frame 204 isoform a [Homo
           sapiens]
          Length = 805

 Score = 32.0 bits (71), Expect = 0.23
 Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 2/72 (2%)

Query: 9   IQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRE 68
           ++++  + ++++ E  RRI  L  E   A + T+  +  Q  QL  +EE    + + + +
Sbjct: 490 LKKKCQKESEQNKEKQRRIETL--EKYLADLPTLDDVQSQSLQLQILEEKNKNLQEALID 547

Query: 69  TEKTLTELNKCC 80
           TEK L E+ K C
Sbjct: 548 TEKKLEEIKKQC 559


>gi|4503593 epidermal growth factor receptor pathway substrate 15
           isoform A [Homo sapiens]
          Length = 896

 Score = 31.6 bits (70), Expect = 0.29
 Identities = 28/167 (16%), Positives = 69/167 (41%), Gaps = 10/167 (5%)

Query: 1   MDNLSSE--EIQQRAHQITDESLESTRRILGLAIESQDAGIKTI---TMLDEQKEQLNRI 55
           +D L++E  ++Q+  + +  +  E    I     E QD   +     T L + + Q  ++
Sbjct: 335 LDTLNNEIVDLQREKNNVEQDLKEKEDTIKQRTSEVQDLQDEVQRENTNLQKLQAQKQQV 394

Query: 56  EEGLDQINKDMRETEKTLTELNKCCG-----LCVCPCNSITNDAREDEMEENLTQVGSIL 110
           +E LD++++   + E+ L E+ K C      +        + +++    EE L +    L
Sbjct: 395 QELLDELDEQKAQLEEQLKEVRKKCAEEAQLISSLKAELTSQESQISTYEEELAKAREEL 454

Query: 111 GNLKDMALNIGNEIDAQNPQIKRITDKADTNRDRIDIANARAKKLID 157
             L+     +   +++   Q++ +      ++  I     +  ++ D
Sbjct: 455 SRLQQETAELEESVESGKAQLEPLQQHLQDSQQEISSMQMKLMEMKD 501


>gi|5032131 syntaxin 6 [Homo sapiens]
          Length = 255

 Score = 31.6 bits (70), Expect = 0.29
 Identities = 13/50 (26%), Positives = 29/50 (58%)

Query: 97  DEMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDRID 146
           ++ +E L  V   +G LK+M+  IG E++ Q   ++  + + ++ + R+D
Sbjct: 167 EQQDEQLELVSGSIGVLKNMSQRIGGELEEQAVMLEDFSHELESTQSRLD 216


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 30.8 bits (68), Expect = 0.50
 Identities = 29/140 (20%), Positives = 57/140 (40%), Gaps = 12/140 (8%)

Query: 7    EEIQQRAHQITDESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDM 66
            E +Q  A  +  + LE  R    +  E +   ++    + E    +N +EE   Q+ K+ 
Sbjct: 1076 ETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKEQKIKEHATTVNELEELQVQLQKEK 1135

Query: 67   RETEKTLTELNKCCGLCVCPCNSITNDAREDE-MEENLTQVGSILGNLKDMALNIGNEID 125
            ++ +KT+ EL             +  DA++   M   +     ++  L     N  N+I+
Sbjct: 1136 KQLQKTMQEL-----------ELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIE 1184

Query: 126  AQNPQIKRITDKADTNRDRI 145
                +IK    K +T ++ I
Sbjct: 1185 DLEQEIKIQKQKQETLQEEI 1204


>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
           sapiens]
          Length = 1591

 Score = 30.8 bits (68), Expect = 0.50
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 1/116 (0%)

Query: 20  SLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTLTELNKC 79
           SL+ T   +   IE     ++       QKE L+   E   +++  ++ETE+   ++ K 
Sbjct: 836 SLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKL 895

Query: 80  CGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDM-ALNIGNEIDAQNPQIKRI 134
            G  VC    + N   E  + ++  +    L N KD   L + N + +QN +IK +
Sbjct: 896 KGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKEL 951


>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
           sapiens]
          Length = 1594

 Score = 30.8 bits (68), Expect = 0.50
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 1/116 (0%)

Query: 20  SLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTLTELNKC 79
           SL+ T   +   IE     ++       QKE L+   E   +++  ++ETE+   ++ K 
Sbjct: 836 SLKCTAVEIRNIIEKVKCSLEITLKEKHQKELLSLKNEYEGKLDGLIKETEENENKIKKL 895

Query: 80  CGLCVCPCNSITNDAREDEMEENLTQVGSILGNLKDM-ALNIGNEIDAQNPQIKRI 134
            G  VC    + N   E  + ++  +    L N KD   L + N + +QN +IK +
Sbjct: 896 KGELVCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQKLLEMENIMHSQNCEIKEL 951


>gi|4759188 syntaxin 8 [Homo sapiens]
          Length = 236

 Score = 30.8 bits (68), Expect = 0.50
 Identities = 14/48 (29%), Positives = 24/48 (50%)

Query: 98  EMEENLTQVGSILGNLKDMALNIGNEIDAQNPQIKRITDKADTNRDRI 145
           E +  L  + SI+   K M   IGNE+D QN  I  + +  +   +++
Sbjct: 150 EQDAGLDALSSIISRQKQMGQEIGNELDEQNEIIDDLANLVENTDEKL 197


>gi|5454166 vesicle transport through interaction with t-SNAREs 1B
           [Homo sapiens]
          Length = 232

 Score = 30.8 bits (68), Expect = 0.50
 Identities = 17/60 (28%), Positives = 34/60 (56%), Gaps = 3/60 (5%)

Query: 19  ESLESTRRILGLAIESQDAGIKTITMLDEQKEQLNRIEEGLDQINKDMRETEKTLTELNK 78
           +S+E + RI   A E+   G + I  L EQ++QL R +  L   ++++ ++ K L  +++
Sbjct: 144 QSIERSHRI---ATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSR 200


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,706,554
Number of Sequences: 37866
Number of extensions: 175822
Number of successful extensions: 1078
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 903
Number of HSP's gapped (non-prelim): 261
length of query: 158
length of database: 18,247,518
effective HSP length: 94
effective length of query: 64
effective length of database: 14,688,114
effective search space: 940039296
effective search space used: 940039296
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.