Search of human proteins with 187608816

Search of human proteins with 187608816

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187608816 apolipoprotein B mRNA editing enzyme, catalytic
polypeptide-like 3D [Homo sapiens]
         (386 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187608816 apolipoprotein B mRNA editing enzyme, catalytic pol...   848   0.0  
gi|22907044 apolipoprotein B mRNA editing enzyme, catalytic poly...   629   e-180
gi|22907025 apolipoprotein B mRNA editing enzyme, catalytic poly...   444   e-125
gi|22907039 apolipoprotein B mRNA editing enzyme, catalytic poly...   311   6e-85
gi|13399304 apolipoprotein B mRNA editing enzyme, catalytic poly...   279   3e-75
gi|10190700 activation-induced cytidine deaminase [Homo sapiens]      132   5e-31
gi|21955158 phorbolin 1 [Homo sapiens]                                120   3e-27
gi|5802978 apolipoprotein B mRNA editing enzyme, catalytic polyp...   106   3e-23
gi|33147089 apolipoprotein B mRNA editing enzyme, catalytic poly...   106   4e-23
gi|61743957 apolipoprotein B mRNA editing enzyme [Homo sapiens]        84   2e-16
gi|54873619 apolipoprotein B mRNA editing enzyme, catalytic poly...    65   8e-11
gi|119395734 breast cancer 2, early onset [Homo sapiens]               30   4.8  
gi|105990535 coagulation factor V precursor [Homo sapiens]             29   6.3  

>gi|187608816 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3D [Homo sapiens]
          Length = 386

 Score =  848 bits (2191), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 1   MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL 60
           MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL
Sbjct: 1   MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL 60

Query: 61  PKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFL 120
           PKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFL
Sbjct: 61  PKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFL 120

Query: 121 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPF 180
           AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPF
Sbjct: 121 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPF 180

Query: 181 MPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKH 240
           MPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKH
Sbjct: 181 MPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKH 240

Query: 241 HSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEV 300
           HSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEV
Sbjct: 241 HSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEV 300

Query: 301 AEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSD 360
           AEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSD
Sbjct: 301 AEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSD 360

Query: 361 DEPFKPWKGLQTNFRLLKRRLREILQ 386
           DEPFKPWKGLQTNFRLLKRRLREILQ
Sbjct: 361 DEPFKPWKGLQTNFRLLKRRLREILQ 386


>gi|22907044 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3F isoform a [Homo sapiens]
          Length = 373

 Score =  629 bits (1621), Expect = e-180
 Identities = 299/386 (77%), Positives = 321/386 (83%), Gaps = 13/386 (3%)

Query: 1   MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL 60
           M P  RN +ERMYRDTF  NF N PIL  R+  WLCYEVK K G S    D  +FRG   
Sbjct: 1   MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRG--- 56

Query: 61  PKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFL 120
                    +VY + E+HAEMCFLSWFCGN+LPA + FQITWFVSW PC  CV K+ +FL
Sbjct: 57  ---------QVYSQPEHHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFL 107

Query: 121 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPF 180
           AEHPNVTLTISAARLYYY +RD+R  L RL +AGARVKIMD E+FAYCWENFV +EGQPF
Sbjct: 108 AEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVKIMDDEEFAYCWENFVYSEGQPF 167

Query: 181 MPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKH 240
           MPWYKFDDNYA LHRTLKEILRNPMEAMYPHIFYFHFKNL KA GRNESWLCFTMEV KH
Sbjct: 168 MPWYKFDDNYAFLHRTLKEILRNPMEAMYPHIFYFHFKNLRKAYGRNESWLCFTMEVVKH 227

Query: 241 HSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEV 300
           HS V  KRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEV
Sbjct: 228 HSPVSWKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEV 287

Query: 301 AEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSD 360
           AEFLARHSNVNLTIFTARL YFWDTDYQEGL SLSQEGASV+IMGYKDF  CW+NFVY+D
Sbjct: 288 AEFLARHSNVNLTIFTARLYYFWDTDYQEGLRSLSQEGASVEIMGYKDFKYCWENFVYND 347

Query: 361 DEPFKPWKGLQTNFRLLKRRLREILQ 386
           DEPFKPWKGL+ NF  L  +L+EIL+
Sbjct: 348 DEPFKPWKGLKYNFLFLDSKLQEILE 373


>gi|22907025 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3B [Homo sapiens]
          Length = 382

 Score =  444 bits (1143), Expect = e-125
 Identities = 233/395 (58%), Positives = 269/395 (68%), Gaps = 26/395 (6%)

Query: 1   MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL 60
           MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRG   
Sbjct: 1   MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRG--- 57

Query: 61  PKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFL 120
                    +VYF+ + HAEMCFLSWFCGN+LPA + FQITWFVSW PC  CV K+ +FL
Sbjct: 58  ---------QVYFKPQYHAEMCFLSWFCGNQLPAYKCFQITWFVSWTPCPDCVAKLAEFL 108

Query: 121 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPF 180
           +EHPNVTLTISAARLYYY +RD+R  L RL +AGARV IMDYE+FAYCWENFV NEGQ F
Sbjct: 109 SEHPNVTLTISAARLYYYWERDYRRALCRLSQAGARVTIMDYEEFAYCWENFVYNEGQQF 168

Query: 181 MPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKH 240
           MPWYKFD+NYA LHRTLKEILR  M+   P  F F+F N      R +++LC+ +E   +
Sbjct: 169 MPWYKFDENYAFLHRTLKEILRYLMD---PDTFTFNFNNDPLVLRRRQTYLCYEVERLDN 225

Query: 241 HSAVF--RKRGVFRNQVDPETHC-----HAERCFLSWFCDDILSPNTNYEVTWYTSWSPC 293
            + V   +  G   N+      C     HAE  FL       L P   Y VTW+ SWSPC
Sbjct: 226 GTWVLMDQHMGFLCNEA-KNLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPC 284

Query: 294 PE--CAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVS 351
               CAGEV  FL  +++V L IF AR+ Y +D  Y+E L  L   GA V IM Y +F  
Sbjct: 285 FSWGCAGEVRAFLQENTHVRLRIFAARI-YDYDPLYKEALQMLRDAGAQVSIMTYDEFEY 343

Query: 352 CWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ 386
           CW  FVY    PF+PW GL+ + + L  RLR ILQ
Sbjct: 344 CWDTFVYRQGCPFQPWDGLEEHSQALSGRLRAILQ 378



 Score =  119 bits (299), Expect = 4e-27
 Identities = 72/191 (37%), Positives = 105/191 (54%), Gaps = 9/191 (4%)

Query: 15  DTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFR 74
           DTF  NF N+P++  R  T+LCYEV+     + +L D  +     L     N     Y R
Sbjct: 196 DTFTFNFNNDPLVLRRRQTYLCYEVERLDNGTWVLMDQHM---GFLCNEAKNLLCGFYGR 252

Query: 75  FENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLP--CVVKVTKFLAEHPNVTLTISA 132
              HAE+ FL      +L   + +++TWF+SW+PC    C  +V  FL E+ +V L I A
Sbjct: 253 ---HAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRIFA 309

Query: 133 ARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYAS 192
           AR+Y Y D  ++  L  L  AGA+V IM Y++F YCW+ FV  +G PF PW   +++  +
Sbjct: 310 ARIYDY-DPLYKEALQMLRDAGAQVSIMTYDEFEYCWDTFVYRQGCPFQPWDGLEEHSQA 368

Query: 193 LHRTLKEILRN 203
           L   L+ IL+N
Sbjct: 369 LSGRLRAILQN 379


>gi|22907039 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3C [Homo sapiens]
          Length = 190

 Score =  311 bits (797), Expect = 6e-85
 Identities = 145/186 (77%), Positives = 159/186 (85%)

Query: 201 LRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETH 260
           +RNPM+AMYP  FYF FKNL +A  RNE+WLCFT+E  K  S V  K GVFRNQVD ETH
Sbjct: 5   IRNPMKAMYPGTFYFQFKNLWEANDRNETWLCFTVEGIKRRSVVSWKTGVFRNQVDSETH 64

Query: 261 CHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLC 320
           CHAERCFLSWFCDDILSPNT Y+VTWYTSWSPCP+CAGEVAEFLARHSNVNLTIFTARL 
Sbjct: 65  CHAERCFLSWFCDDILSPNTKYQVTWYTSWSPCPDCAGEVAEFLARHSNVNLTIFTARLY 124

Query: 321 YFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRR 380
           YF    YQEGL SLSQEG +V+IM Y+DF  CW+NFVY+D+EPFKPWKGL+TNFRLLKRR
Sbjct: 125 YFQYPCYQEGLRSLSQEGVAVEIMDYEDFKYCWENFVYNDNEPFKPWKGLKTNFRLLKRR 184

Query: 381 LREILQ 386
           LRE LQ
Sbjct: 185 LRESLQ 190



 Score =  190 bits (483), Expect = 2e-48
 Identities = 95/202 (47%), Positives = 122/202 (60%), Gaps = 12/202 (5%)

Query: 1   MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL 60
           MNPQIRNPM+ MY  TFY  F+N      R+ TWLC+ V+  + RS + W TGVFR  V 
Sbjct: 1   MNPQIRNPMKAMYPGTFYFQFKNLWEANDRNETWLCFTVEGIKRRSVVSWKTGVFRNQVD 60

Query: 61  PKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFL 120
            +               HAE CFLSWFC + L  N ++Q+TW+ SW+PC  C  +V +FL
Sbjct: 61  SETHC------------HAERCFLSWFCDDILSPNTKYQVTWYTSWSPCPDCAGEVAEFL 108

Query: 121 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPF 180
           A H NV LTI  ARLYY++   ++  L  L + G  V+IMDYEDF YCWENFV N+ +PF
Sbjct: 109 ARHSNVNLTIFTARLYYFQYPCYQEGLRSLSQEGVAVEIMDYEDFKYCWENFVYNDNEPF 168

Query: 181 MPWYKFDDNYASLHRTLKEILR 202
            PW     N+  L R L+E L+
Sbjct: 169 KPWKGLKTNFRLLKRRLRESLQ 190


>gi|13399304 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3G [Homo sapiens]
          Length = 384

 Score =  279 bits (713), Expect = 3e-75
 Identities = 165/398 (41%), Positives = 224/398 (56%), Gaps = 30/398 (7%)

Query: 1   MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVL 60
           M P  RN +ERMYRDTF  NF N PIL  R+  WLCYEVK K G S    D  +FRG   
Sbjct: 1   MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPPLDAKIFRG--- 56

Query: 61  PKRQSNHRQEVYFRFENHAEMCFLSWFCG-NRLPANRRFQITWFVSWNPCLPCVVKVTKF 119
                    +VY   + H EM F  WF    +L  ++ +++TW++SW+PC  C   +  F
Sbjct: 57  ---------QVYSELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATF 107

Query: 120 LAEHPNVTLTISAARLYYYRDRDWRWVLLRLHK----AGARVKIMDYEDFAYCWENFVCN 175
           LAE P VTLTI  ARLYY+ D D++  L  L +      A +KIM+Y++F +CW  FV +
Sbjct: 108 LAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYS 167

Query: 176 EGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTM 235
           + + F PW      Y  LH  L EILR+ M+   P  F F+F N     GR+E++LC+ +
Sbjct: 168 QRELFEPWNNLPKYYILLHIMLGEILRHSMD---PPTFTFNFNNEPWVRGRHETYLCYEV 224

Query: 236 EVTKHHSAVF--RKRGVFRNQVDPETH-----CHAERCFLSWFCDDILSPNTNYEVTWYT 288
           E   + + V   ++RG   NQ  P  H      HAE CFL       L  + +Y VT +T
Sbjct: 225 ERMHNDTWVLLNQRRGFLCNQA-PHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFT 283

Query: 289 SWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKD 348
           SWSPC  CA E+A+F++++ +V+L IFTAR+ Y      QEGL +L++ GA + IM Y +
Sbjct: 284 SWSPCFSCAQEMAKFISKNKHVSLCIFTARI-YDDQGRCQEGLRTLAEAGAKISIMTYSE 342

Query: 349 FVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ 386
           F  CW  FV     PF+PW GL  + + L  RLR ILQ
Sbjct: 343 FKHCWDTFVDHQGCPFQPWDGLDEHSQDLSGRLRAILQ 380



 Score =  117 bits (292), Expect = 2e-26
 Identities = 67/188 (35%), Positives = 105/188 (55%), Gaps = 7/188 (3%)

Query: 16  TFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRF 75
           TF  NF NEP + GR  T+LCYEV+     + +L +    RG +  +    H     F  
Sbjct: 201 TFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQR--RGFLCNQAPHKHG----FLE 254

Query: 76  ENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARL 135
             HAE+CFL      +L  ++ +++T F SW+PC  C  ++ KF++++ +V+L I  AR+
Sbjct: 255 GRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFISKNKHVSLCIFTARI 314

Query: 136 YYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHR 195
           Y  + R     L  L +AGA++ IM Y +F +CW+ FV ++G PF PW   D++   L  
Sbjct: 315 YDDQGRCQEG-LRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLDEHSQDLSG 373

Query: 196 TLKEILRN 203
            L+ IL+N
Sbjct: 374 RLRAILQN 381


>gi|10190700 activation-induced cytidine deaminase [Homo sapiens]
          Length = 198

 Score =  132 bits (332), Expect = 5e-31
 Identities = 71/174 (40%), Positives = 98/174 (56%), Gaps = 5/174 (2%)

Query: 213 FYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFC 272
           F + FKN+  A GR E++LC+ ++     ++     G  RN+      CH E  FL +  
Sbjct: 11  FLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNK----NGCHVELLFLRYIS 66

Query: 273 DDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQ-EGL 331
           D  L P   Y VTW+TSWSPC +CA  VA+FL  + N++L IFTARL +  D   + EGL
Sbjct: 67  DWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGL 126

Query: 332 CSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREIL 385
             L + G  + IM +KD+  CW  FV + +  FK W+GL  N   L R+LR IL
Sbjct: 127 RRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRIL 180



 Score =  113 bits (282), Expect = 3e-25
 Identities = 68/193 (35%), Positives = 93/193 (48%), Gaps = 21/193 (10%)

Query: 12  MYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEV 71
           M R  F   F+N     GR  T+LCY VK +   ++   D G                  
Sbjct: 6   MNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFG------------------ 47

Query: 72  YFRFEN--HAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLT 129
           Y R +N  H E+ FL +     L   R +++TWF SW+PC  C   V  FL  +PN++L 
Sbjct: 48  YLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLR 107

Query: 130 ISAARLYYYRDRDWR-WVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDD 188
           I  ARLY+  DR      L RLH+AG ++ IM ++D+ YCW  FV N  + F  W    +
Sbjct: 108 IFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHE 167

Query: 189 NYASLHRTLKEIL 201
           N   L R L+ IL
Sbjct: 168 NSVRLSRQLRRIL 180


>gi|21955158 phorbolin 1 [Homo sapiens]
          Length = 199

 Score =  120 bits (300), Expect = 3e-27
 Identities = 78/192 (40%), Positives = 100/192 (52%), Gaps = 14/192 (7%)

Query: 204 PMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVF--RKRGVFRNQVDPETHC 261
           P   M PHIF  +F N     GR++++LC+ +E   + ++V   + RG   NQ      C
Sbjct: 9   PRHLMDPHIFTSNFNN---GIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK-NLLC 64

Query: 262 -----HAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPE--CAGEVAEFLARHSNVNLTI 314
                HAE  FL       L P   Y VTW+ SWSPC    CAGEV  FL  +++V L I
Sbjct: 65  GFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHVRLRI 124

Query: 315 FTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNF 374
           F AR+ Y +D  Y+E L  L   GA V IM Y +F  CW  FV     PF+PW GL  + 
Sbjct: 125 FAARI-YDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLDEHS 183

Query: 375 RLLKRRLREILQ 386
           + L  RLR ILQ
Sbjct: 184 QALSGRLRAILQ 195



 Score =  110 bits (274), Expect = 3e-24
 Identities = 73/198 (36%), Positives = 105/198 (53%), Gaps = 12/198 (6%)

Query: 8   PMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNH 67
           P   M    F  NF N     GR  T+LCYEV+     +++  D    RG  L  +  N 
Sbjct: 9   PRHLMDPHIFTSNFNNG---IGRHKTYLCYEVERLDNGTSVKMDQ--HRG-FLHNQAKNL 62

Query: 68  RQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLP--CVVKVTKFLAEHPN 125
               Y R   HAE+ FL      +L   + +++TWF+SW+PC    C  +V  FL E+ +
Sbjct: 63  LCGFYGR---HAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTH 119

Query: 126 VTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYK 185
           V L I AAR+Y Y D  ++  L  L  AGA+V IM Y++F +CW+ FV ++G PF PW  
Sbjct: 120 VRLRIFAARIYDY-DPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDG 178

Query: 186 FDDNYASLHRTLKEILRN 203
            D++  +L   L+ IL+N
Sbjct: 179 LDEHSQALSGRLRAILQN 196


>gi|5802978 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 2 [Homo sapiens]
          Length = 224

 Score =  106 bits (265), Expect = 3e-23
 Identities = 62/199 (31%), Positives = 98/199 (49%), Gaps = 13/199 (6%)

Query: 197 LKEILRNPM------EAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGV 250
           LKE++  P       E +  + F F F+N+  + GRN+++LC+ +E       V   RG 
Sbjct: 30  LKELIELPPFEIVTGERLPANFFKFQFRNVEYSSGRNKTFLCYVVEAQGKGGQVQASRGY 89

Query: 251 FRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNV 310
                D     HAE  F +        P   Y VTWY S SPC  CA  + + L++  N+
Sbjct: 90  LE---DEHAAAHAEEAFFNTILP-AFDPALRYNVTWYVSSSPCAACADRIIKTLSKTKNL 145

Query: 311 NLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDD---EPFKPW 367
            L I   RL  + + + Q  L  L + G  ++IM  +DF   W+NFV  ++   + F+PW
Sbjct: 146 RLLILVGRLFMWEEPEIQAALKKLKEAGCKLRIMKPQDFEYVWQNFVEQEEGESKAFQPW 205

Query: 368 KGLQTNFRLLKRRLREILQ 386
           + +Q NF   + +L +IL+
Sbjct: 206 EDIQENFLYYEEKLADILK 224



 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 57/199 (28%), Positives = 97/199 (48%), Gaps = 25/199 (12%)

Query: 10  ERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQ 69
           ER+  + F   F N     GR+ T+LCY V+ + G+   +  +   RG +  +  + H +
Sbjct: 45  ERLPANFFKFQFRNVEYSSGRNKTFLCYVVEAQ-GKGGQVQAS---RGYLEDEHAAAHAE 100

Query: 70  EVYFRFENHAEMCFLSWFCGNRLPA---NRRFQITWFVSWNPCLPCVVKVTKFLAEHPNV 126
           E +F                  LPA     R+ +TW+VS +PC  C  ++ K L++  N+
Sbjct: 101 EAFFN---------------TILPAFDPALRYNVTWYVSSSPCAACADRIIKTLSKTKNL 145

Query: 127 TLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFV---CNEGQPFMPW 183
            L I   RL+ + + + +  L +L +AG +++IM  +DF Y W+NFV     E + F PW
Sbjct: 146 RLLILVGRLFMWEEPEIQAALKKLKEAGCKLRIMKPQDFEYVWQNFVEQEEGESKAFQPW 205

Query: 184 YKFDDNYASLHRTLKEILR 202
               +N+      L +IL+
Sbjct: 206 EDIQENFLYYEEKLADILK 224


>gi|33147089 apolipoprotein B mRNA editing enzyme, catalytic
           polypeptide-like 3H [Homo sapiens]
          Length = 183

 Score =  106 bits (264), Expect = 4e-23
 Identities = 56/143 (39%), Positives = 77/143 (53%), Gaps = 8/143 (5%)

Query: 248 RGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARH 307
           RG F N+      CHAE CF++      L     Y+VT Y +WSPC  CA E+ +F+  H
Sbjct: 44  RGYFENK----KKCHAEICFINEIKSMGLDETQCYQVTCYLTWSPCSSCAWELVDFIKAH 99

Query: 308 SNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDD----EP 363
            ++NL IF +RL Y W    Q+GL  L      V++MG+ +F  CW+NFV  +      P
Sbjct: 100 DHLNLGIFASRLYYHWCKPQQKGLRLLCGSQVPVEVMGFPEFADCWENFVDHEKPLSFNP 159

Query: 364 FKPWKGLQTNFRLLKRRLREILQ 386
           +K  + L  N R +KRRL  I Q
Sbjct: 160 YKMLEELDKNSRAIKRRLERIKQ 182



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 43/134 (32%), Positives = 73/134 (54%), Gaps = 8/134 (5%)

Query: 75  FEN----HAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTI 130
           FEN    HAE+CF++      L   + +Q+T +++W+PC  C  ++  F+  H ++ L I
Sbjct: 47  FENKKKCHAEICFINEIKSMGLDETQCYQVTCYLTWSPCSSCAWELVDFIKAHDHLNLGI 106

Query: 131 SAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEG----QPFMPWYKF 186
            A+RLYY+  +  +  L  L  +   V++M + +FA CWENFV +E      P+    + 
Sbjct: 107 FASRLYYHWCKPQQKGLRLLCGSQVPVEVMGFPEFADCWENFVDHEKPLSFNPYKMLEEL 166

Query: 187 DDNYASLHRTLKEI 200
           D N  ++ R L+ I
Sbjct: 167 DKNSRAIKRRLERI 180


>gi|61743957 apolipoprotein B mRNA editing enzyme [Homo sapiens]
          Length = 236

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 57/173 (32%), Positives = 79/173 (45%), Gaps = 27/173 (15%)

Query: 2   NPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLP 61
           +P +R  +E    D FYD  E       R    L YE  IK G S  +W           
Sbjct: 11  DPTLRRRIEPWEFDVFYDPREL------RKEACLLYE--IKWGMSRKIW----------- 51

Query: 62  KRQSNHRQEVYFRFENHAEMCFLSWFCGNR-LPANRRFQITWFVSWNPCLPCVVKVTKFL 120
            R S           NH E+ F+  F   R    +    ITWF+SW+PC  C   + +FL
Sbjct: 52  -RSSGKNTT------NHVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFL 104

Query: 121 AEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFV 173
           + HP VTL I  ARL+++ D+  R  L  L  +G  ++IM   ++ +CW NFV
Sbjct: 105 SRHPGVTLVIYVARLFWHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFV 157



 Score = 82.0 bits (201), Expect = 8e-16
 Identities = 37/97 (38%), Positives = 56/97 (57%), Gaps = 1/97 (1%)

Query: 262 HAERCFLSWFCDDI-LSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLC 320
           H E  F+  F  +    P+ +  +TW+ SWSPC EC+  + EFL+RH  V L I+ ARL 
Sbjct: 61  HVEVNFIKKFTSERDFHPSMSCSITWFLSWSPCWECSQAIREFLSRHPGVTLVIYVARLF 120

Query: 321 YFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFV 357
           +  D   ++GL  L   G +++IM   ++  CW+NFV
Sbjct: 121 WHMDQQNRQGLRDLVNSGVTIQIMRASEYYHCWRNFV 157


>gi|54873619 apolipoprotein B mRNA editing enzyme, catalytic
          polypeptide-like 3F isoform b [Homo sapiens]
          Length = 101

 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 34/59 (57%), Positives = 37/59 (62%), Gaps = 1/59 (1%)

Query: 1  MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPV 59
          M P  RN +ERMYRDTF  NF N PIL  R+  WLCYEVK K G S    D  +FRG V
Sbjct: 1  MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTK-GPSRPRLDAKIFRGQV 58



 Score = 36.2 bits (82), Expect = 0.051
 Identities = 28/90 (31%), Positives = 39/90 (43%), Gaps = 2/90 (2%)

Query: 197 LKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVD 256
           +K   RN +E MY   F ++F N      RN  WLC+ ++ TK  S       +FR QV 
Sbjct: 1   MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVK-TKGPSRPRLDAKIFRGQV- 58

Query: 257 PETHCHAERCFLSWFCDDILSPNTNYEVTW 286
           P +   A    LS        P+   +V W
Sbjct: 59  PRSFIRAPFQVLSSPFGQCAPPHGTAQVQW 88


>gi|119395734 breast cancer 2, early onset [Homo sapiens]
          Length = 3418

 Score = 29.6 bits (65), Expect = 4.8
 Identities = 24/102 (23%), Positives = 42/102 (41%), Gaps = 11/102 (10%)

Query: 194  HRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRN 253
            H T+K++           IF   F  ++K    N+S +C T  +   + A+     +  N
Sbjct: 1856 HETIKKV---------KDIFTDSFSKVIKENNENKSKICQTKIMAGCYEALDDSEDILHN 1906

Query: 254  QVD-PETHCHAERCFLSWFCDDILSPNTNYE-VTWYTSWSPC 293
             +D  E   H+ + F     ++IL  N N   +   +  SPC
Sbjct: 1907 SLDNDECSTHSHKVFADIQSEEILQHNQNMSGLEKVSKISPC 1948


>gi|105990535 coagulation factor V precursor [Homo sapiens]
          Length = 2224

 Score = 29.3 bits (64), Expect = 6.3
 Identities = 14/43 (32%), Positives = 21/43 (48%), Gaps = 1/43 (2%)

Query: 270  WFCDD-ILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVN 311
            WF +D  + PN++Y   W+ +    PE  G      A +S VN
Sbjct: 1693 WFKEDNAVQPNSSYTYVWHATERSGPESPGSACRAWAYYSAVN 1735


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.140    0.489 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,981,769
Number of Sequences: 37866
Number of extensions: 718084
Number of successful extensions: 1686
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1617
Number of HSP's gapped (non-prelim): 25
length of query: 386
length of database: 18,247,518
effective HSP length: 104
effective length of query: 282
effective length of database: 14,309,454
effective search space: 4035266028
effective search space used: 4035266028
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.