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Search of human proteins with 187608585
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187608585 CASP8 and FADD-like apoptosis regulator isoform 2
[Homo sapiens]
(221 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187608585 CASP8 and FADD-like apoptosis regulator isoform 2 [... 433 e-122
gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1 [... 392 e-109
gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1 [... 392 e-109
gi|122056474 caspase 8 isoform C precursor [Homo sapiens] 73 2e-13
gi|15718708 caspase 8 isoform C precursor [Homo sapiens] 73 2e-13
gi|122056476 caspase 8 isoform G precursor [Homo sapiens] 72 4e-13
gi|15718712 caspase 8 isoform E [Homo sapiens] 72 4e-13
gi|15718706 caspase 8 isoform B precursor [Homo sapiens] 72 4e-13
gi|15718704 caspase 8 isoform A precursor [Homo sapiens] 57 1e-08
gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens] 57 1e-08
gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens] 57 1e-08
gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens] 57 1e-08
gi|4505229 Fas-associated via death domain [Homo sapiens] 39 0.004
gi|149944486 hypothetical protein LOC389643 [Homo sapiens] 32 0.33
gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens] 30 1.2
gi|31621305 leucine-rich PPR motif-containing protein [Homo sapi... 30 1.2
gi|164519084 RAB GTPase activating protein 1 [Homo sapiens] 30 2.1
gi|154813197 talpid3 protein [Homo sapiens] 30 2.1
gi|156105697 ring finger and CCCH-type zinc finger domains 2 iso... 29 2.8
gi|156105699 ring finger and CCCH-type zinc finger domains 2 iso... 29 2.8
gi|116805342 human immunodeficiency virus type I enhancer bindin... 29 3.6
gi|22748787 hypothetical protein LOC126695 [Homo sapiens] 28 6.2
gi|4557663 immunoglobulin binding protein 1 [Homo sapiens] 28 8.1
gi|4503097 casein kinase 2, alpha prime polypeptide [Homo sapiens] 28 8.1
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 28 8.1
>gi|187608585 CASP8 and FADD-like apoptosis regulator isoform 2
[Homo sapiens]
Length = 221
Score = 433 bits (1114), Expect = e-122
Identities = 221/221 (100%), Positives = 221/221 (100%)
Query: 1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY 60
MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
Sbjct: 1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY 60
Query: 61 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM 120
RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
Sbjct: 61 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM 120
Query: 121 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT 180
GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
Sbjct: 121 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT 180
Query: 181 SYRNVLQAAIQKSLKDPSNNFRMITPYAHCPDLKILGNCSM 221
SYRNVLQAAIQKSLKDPSNNFRMITPYAHCPDLKILGNCSM
Sbjct: 181 SYRNVLQAAIQKSLKDPSNNFRMITPYAHCPDLKILGNCSM 221
>gi|187608577 CASP8 and FADD-like apoptosis regulator isoform 1
[Homo sapiens]
Length = 480
Score = 392 bits (1007), Expect = e-109
Identities = 202/203 (99%), Positives = 203/203 (100%)
Query: 1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY 60
MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
Sbjct: 1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY 60
Query: 61 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM 120
RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
Sbjct: 61 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM 120
Query: 121 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT 180
GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
Sbjct: 121 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT 180
Query: 181 SYRNVLQAAIQKSLKDPSNNFRM 203
SYRNVLQAAIQKSLKDPSNNFR+
Sbjct: 181 SYRNVLQAAIQKSLKDPSNNFRL 203
>gi|187608571 CASP8 and FADD-like apoptosis regulator isoform 1
[Homo sapiens]
Length = 480
Score = 392 bits (1007), Expect = e-109
Identities = 202/203 (99%), Positives = 203/203 (100%)
Query: 1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY 60
MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY
Sbjct: 1 MSAEVIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLY 60
Query: 61 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM 120
RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM
Sbjct: 61 RVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYM 120
Query: 121 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT 180
GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT
Sbjct: 121 GRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGT 180
Query: 181 SYRNVLQAAIQKSLKDPSNNFRM 203
SYRNVLQAAIQKSLKDPSNNFR+
Sbjct: 181 SYRNVLQAAIQKSLKDPSNNFRL 203
>gi|122056474 caspase 8 isoform C precursor [Homo sapiens]
Length = 464
Score = 72.8 bits (177), Expect = 2e-13
Identities = 49/179 (27%), Positives = 98/179 (54%), Gaps = 8/179 (4%)
Query: 6 IHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDI---LRERGKLSVGDLA---ELL 59
++ + E LD+++ L FL D ++D L + L+E+ L +L+ ELL
Sbjct: 7 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66
Query: 60 YRVRRFDLLKRILKMDRKAVETHLLRNPHL-VSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118
+R+ R DLL L ++ +E L +S YRV++ +I E++ +S++ S FL+++
Sbjct: 67 FRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 126
Query: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQG 177
+ + K+ + + LD+ +E+EK ++ +LD+L++ I++ LK I Y++ +G
Sbjct: 127 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKI-INDYEEFSKG 184
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/122 (26%), Positives = 62/122 (50%), Gaps = 9/122 (7%)
Query: 92 DYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDL 151
D+ + +IGE LD D++SL FL DY+ + K K L L L++ ++ L
Sbjct: 2 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF 61
Query: 152 LEKCLKNIHRID-----LKTKIQKYKQSVQGAG----TSYRNVLQAAIQKSLKDPSNNFR 202
L++ L I+R+D L T+ ++ ++ +Q G ++YR +L ++ + +F+
Sbjct: 62 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK 121
Query: 203 MI 204
+
Sbjct: 122 FL 123
>gi|15718708 caspase 8 isoform C precursor [Homo sapiens]
Length = 464
Score = 72.8 bits (177), Expect = 2e-13
Identities = 49/179 (27%), Positives = 98/179 (54%), Gaps = 8/179 (4%)
Query: 6 IHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDI---LRERGKLSVGDLA---ELL 59
++ + E LD+++ L FL D ++D L + L+E+ L +L+ ELL
Sbjct: 7 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66
Query: 60 YRVRRFDLLKRILKMDRKAVETHLLRNPHL-VSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118
+R+ R DLL L ++ +E L +S YRV++ +I E++ +S++ S FL+++
Sbjct: 67 FRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 126
Query: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQG 177
+ + K+ + + LD+ +E+EK ++ +LD+L++ I++ LK I Y++ +G
Sbjct: 127 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKI-INDYEEFSKG 184
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/122 (26%), Positives = 62/122 (50%), Gaps = 9/122 (7%)
Query: 92 DYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDL 151
D+ + +IGE LD D++SL FL DY+ + K K L L L++ ++ L
Sbjct: 2 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF 61
Query: 152 LEKCLKNIHRID-----LKTKIQKYKQSVQGAG----TSYRNVLQAAIQKSLKDPSNNFR 202
L++ L I+R+D L T+ ++ ++ +Q G ++YR +L ++ + +F+
Sbjct: 62 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK 121
Query: 203 MI 204
+
Sbjct: 122 FL 123
>gi|122056476 caspase 8 isoform G precursor [Homo sapiens]
Length = 538
Score = 72.0 bits (175), Expect = 4e-13
Identities = 51/193 (26%), Positives = 103/193 (53%), Gaps = 15/193 (7%)
Query: 6 IHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDI---LRERGKLSVGDLA---ELL 59
++ + E LD+++ L FL D ++D L + L+E+ L +L+ ELL
Sbjct: 66 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 125
Query: 60 YRVRRFDLLKRILKMDRKAVETHLLRNPHL-VSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118
+R+ R DLL L ++ +E L +S YRV++ +I E++ +S++ S FL+++
Sbjct: 126 FRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 185
Query: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQ----- 173
+ + K+ + + LD+ +E+EK ++ +LD+L++ I++ LK I Y++
Sbjct: 186 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKI-INDYEEFSKER 244
Query: 174 --SVQGAGTSYRN 184
S++G+ + N
Sbjct: 245 SSSLEGSPDEFSN 257
Score = 46.2 bits (108), Expect = 2e-05
Identities = 33/127 (25%), Positives = 63/127 (49%), Gaps = 9/127 (7%)
Query: 87 PHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAP 146
P D+ + +IGE LD D++SL FL DY+ + K K L L L++ ++
Sbjct: 56 PFKKMDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEE 115
Query: 147 DQLDLLEKCLKNIHRID-----LKTKIQKYKQSVQGAG----TSYRNVLQAAIQKSLKDP 197
L L++ L I+R+D L T+ ++ ++ +Q G ++YR +L ++ +
Sbjct: 116 SNLSFLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSE 175
Query: 198 SNNFRMI 204
+F+ +
Sbjct: 176 LRSFKFL 182
>gi|15718712 caspase 8 isoform E [Homo sapiens]
Length = 235
Score = 72.0 bits (175), Expect = 4e-13
Identities = 51/193 (26%), Positives = 103/193 (53%), Gaps = 15/193 (7%)
Query: 6 IHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDI---LRERGKLSVGDLA---ELL 59
++ + E LD+++ L FL D ++D L + L+E+ L +L+ ELL
Sbjct: 7 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66
Query: 60 YRVRRFDLLKRILKMDRKAVETHLLRNPHL-VSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118
+R+ R DLL L ++ +E L +S YRV++ +I E++ +S++ S FL+++
Sbjct: 67 FRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 126
Query: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQ----- 173
+ + K+ + + LD+ +E+EK ++ +LD+L++ I++ LK I Y++
Sbjct: 127 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKI-INDYEEFSKER 185
Query: 174 --SVQGAGTSYRN 184
S++G+ + N
Sbjct: 186 SSSLEGSPDEFSN 198
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/122 (26%), Positives = 62/122 (50%), Gaps = 9/122 (7%)
Query: 92 DYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDL 151
D+ + +IGE LD D++SL FL DY+ + K K L L L++ ++ L
Sbjct: 2 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF 61
Query: 152 LEKCLKNIHRID-----LKTKIQKYKQSVQGAG----TSYRNVLQAAIQKSLKDPSNNFR 202
L++ L I+R+D L T+ ++ ++ +Q G ++YR +L ++ + +F+
Sbjct: 62 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK 121
Query: 203 MI 204
+
Sbjct: 122 FL 123
>gi|15718706 caspase 8 isoform B precursor [Homo sapiens]
Length = 479
Score = 72.0 bits (175), Expect = 4e-13
Identities = 51/193 (26%), Positives = 103/193 (53%), Gaps = 15/193 (7%)
Query: 6 IHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDI---LRERGKLSVGDLA---ELL 59
++ + E LD+++ L FL D ++D L + L+E+ L +L+ ELL
Sbjct: 7 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66
Query: 60 YRVRRFDLLKRILKMDRKAVETHLLRNPHL-VSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118
+R+ R DLL L ++ +E L +S YRV++ +I E++ +S++ S FL+++
Sbjct: 67 FRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFKFLLQE 126
Query: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQ----- 173
+ + K+ + + LD+ +E+EK ++ +LD+L++ I++ LK I Y++
Sbjct: 127 EISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKI-INDYEEFSKER 185
Query: 174 --SVQGAGTSYRN 184
S++G+ + N
Sbjct: 186 SSSLEGSPDEFSN 198
Score = 45.8 bits (107), Expect = 3e-05
Identities = 32/122 (26%), Positives = 62/122 (50%), Gaps = 9/122 (7%)
Query: 92 DYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDL 151
D+ + +IGE LD D++SL FL DY+ + K K L L L++ ++ L
Sbjct: 2 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF 61
Query: 152 LEKCLKNIHRID-----LKTKIQKYKQSVQGAG----TSYRNVLQAAIQKSLKDPSNNFR 202
L++ L I+R+D L T+ ++ ++ +Q G ++YR +L ++ + +F+
Sbjct: 62 LKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSFK 121
Query: 203 MI 204
+
Sbjct: 122 FL 123
>gi|15718704 caspase 8 isoform A precursor [Homo sapiens]
Length = 496
Score = 57.4 bits (137), Expect = 1e-08
Identities = 50/213 (23%), Positives = 99/213 (46%), Gaps = 44/213 (20%)
Query: 6 IHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDI---LRERGKLSVGDLA---ELL 59
++ + E LD+++ L FL D ++D L + L+E+ L +L+ ELL
Sbjct: 7 LYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSFLKELL 66
Query: 60 YRVRRFDLLKRILKMDRKAVETHLL----------------------------------- 84
+R+ R DLL L ++ +E L
Sbjct: 67 FRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRFHFCRMSWAEANSQCQTQSVPFWR 126
Query: 85 RNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLV 144
R HL+ RV++ +I E++ +S++ S FL+++ + + K+ + + LD+ +E+EK ++
Sbjct: 127 RVDHLL--IRVMLYQISEEVSRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVIL 184
Query: 145 APDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQG 177
+LD+L++ I++ LK I Y++ +G
Sbjct: 185 GEGKLDILKRVCAQINKSLLKI-INDYEEFSKG 216
Score = 43.9 bits (102), Expect = 1e-04
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 5/93 (5%)
Query: 92 DYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDL 151
D+ + +IGE LD D++SL FL DY+ + K K L L L++ ++ L
Sbjct: 2 DFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLSF 61
Query: 152 LEKCLKNIHRID-----LKTKIQKYKQSVQGAG 179
L++ L I+R+D L T+ ++ ++ +Q G
Sbjct: 62 LKELLFRINRLDLLITYLNTRKEEMERELQTPG 94
>gi|47078272 caspase 10 isoform d preproprotein [Homo sapiens]
Length = 522
Score = 57.0 bits (136), Expect = 1e-08
Identities = 60/205 (29%), Positives = 91/205 (44%), Gaps = 28/205 (13%)
Query: 9 VEEALDTDEKEMLLFLCRDVAIDVVP-------PNVRDLLDILRERGKLSVGD---LAEL 58
++ L + E L FLC I +VP + D+ + L LS D LAEL
Sbjct: 27 IDSNLGVQDVENLKFLC----IGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAEL 82
Query: 59 LYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118
LY +R+ LL+ L ++ VE LL VS +R L+ E+ E +D ++ +IFL+KD
Sbjct: 83 LYIIRQKKLLQH-LNCTKEEVE-RLLPTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKD 140
Query: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLE--------KCLKNIHRIDLKTKIQK 170
+ + E + L + LEK + D L LE K L+NI + + IQ
Sbjct: 141 SLPK----TEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPKLLRNIEKYKREKAIQI 196
Query: 171 YKQSVQGAGTSYRNVLQAAIQKSLK 195
V SY+ + Q +K
Sbjct: 197 VTPPVDKEAESYQGEEELVSQTDVK 221
>gi|47078269 caspase 10 isoform b preproprotein [Homo sapiens]
Length = 521
Score = 57.0 bits (136), Expect = 1e-08
Identities = 60/205 (29%), Positives = 91/205 (44%), Gaps = 28/205 (13%)
Query: 9 VEEALDTDEKEMLLFLCRDVAIDVVP-------PNVRDLLDILRERGKLSVGD---LAEL 58
++ L + E L FLC I +VP + D+ + L LS D LAEL
Sbjct: 27 IDSNLGVQDVENLKFLC----IGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAEL 82
Query: 59 LYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118
LY +R+ LL+ L ++ VE LL VS +R L+ E+ E +D ++ +IFL+KD
Sbjct: 83 LYIIRQKKLLQH-LNCTKEEVE-RLLPTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKD 140
Query: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLE--------KCLKNIHRIDLKTKIQK 170
+ + E + L + LEK + D L LE K L+NI + + IQ
Sbjct: 141 SLPK----TEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPKLLRNIEKYKREKAIQI 196
Query: 171 YKQSVQGAGTSYRNVLQAAIQKSLK 195
V SY+ + Q +K
Sbjct: 197 VTPPVDKEAESYQGEEELVSQTDVK 221
>gi|47078267 caspase 10 isoform a preproprotein [Homo sapiens]
Length = 479
Score = 57.0 bits (136), Expect = 1e-08
Identities = 60/205 (29%), Positives = 91/205 (44%), Gaps = 28/205 (13%)
Query: 9 VEEALDTDEKEMLLFLCRDVAIDVVP-------PNVRDLLDILRERGKLSVGD---LAEL 58
++ L + E L FLC I +VP + D+ + L LS D LAEL
Sbjct: 27 IDSNLGVQDVENLKFLC----IGLVPNKKLEKSSSASDVFEHLLAEDLLSEEDPFFLAEL 82
Query: 59 LYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKD 118
LY +R+ LL+ L ++ VE LL VS +R L+ E+ E +D ++ +IFL+KD
Sbjct: 83 LYIIRQKKLLQH-LNCTKEEVE-RLLPTRQRVSLFRNLLYELSEGIDSENLKDMIFLLKD 140
Query: 119 YMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLE--------KCLKNIHRIDLKTKIQK 170
+ + E + L + LEK + D L LE K L+NI + + IQ
Sbjct: 141 SLPK----TEMTSLSFLAFLEKQGKIDEDNLTCLEDLCKTVVPKLLRNIEKYKREKAIQI 196
Query: 171 YKQSVQGAGTSYRNVLQAAIQKSLK 195
V SY+ + Q +K
Sbjct: 197 VTPPVDKEAESYQGEEELVSQTDVK 221
>gi|4505229 Fas-associated via death domain [Homo sapiens]
Length = 208
Score = 38.9 bits (89), Expect = 0.004
Identities = 47/188 (25%), Positives = 75/188 (39%), Gaps = 16/188 (8%)
Query: 5 VIHQVEEALDTDEKEMLLFLCRDVAIDVVPPNVR---DLLDILRERGKLSVGD---LAEL 58
++H V +L + E L FLC V+ DL +L E+ L G L EL
Sbjct: 7 LLHSVSSSLSSSELTELKFLCLGRVGKRKLERVQSGLDLFSMLLEQNDLEPGHTELLREL 66
Query: 59 LYRVRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGED-------LDKSDVSS 111
L +RR DLL+R+ + A L + + V+ +G+D L SD
Sbjct: 67 LASLRRHDLLRRVDDFEAGAAAGAAPGEEDLCAAFNVICDNVGKDWRRLARQLKVSDTK- 125
Query: 112 LIFLMKDYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKY 171
I ++D R + + L + EK N + L C N+ DL ++Q+
Sbjct: 126 -IDSIEDRYPRNLTERVRESLRIWKNTEKENATVAHLVGALRSCQMNL-VADLVQEVQQA 183
Query: 172 KQSVQGAG 179
+ +G
Sbjct: 184 RDLQNRSG 191
>gi|149944486 hypothetical protein LOC389643 [Homo sapiens]
Length = 796
Score = 32.3 bits (72), Expect = 0.33
Identities = 49/216 (22%), Positives = 88/216 (40%), Gaps = 39/216 (18%)
Query: 10 EEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRER--GKLSVGDLAEL------LYR 61
E+ L+ K CRDVA+ V + L + LRER G ++ E + +
Sbjct: 331 EDLLNESIKACQRGFCRDVALVVTKMDKLHLPEYLRERKAGNQAIQSQREAVLERNEMIK 390
Query: 62 VRRFDLLKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMG 121
++R +LK LK A + +L LV Y V E + ++ + I +++Y+
Sbjct: 391 LQRTRILKEKLKRKLPA-DFKVLEASDLV--YTVSAQEYWQQALLTEEETEIPKLREYIR 447
Query: 122 RGKISKEKSFLDLVV------------------------ELEKLNLVAPDQLDLLEKCLK 157
+ + K+K + V + L A ++++LLEK +
Sbjct: 448 KSLLDKKKRTVTKYVTEAFGLLLLTDSFNSTQNLPNEHLHMSVLRRFAEEKVELLEKAIA 507
Query: 158 NIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQKS 193
Q ++ V+ A TSYR +L+A + +S
Sbjct: 508 QC----FACMEQPLQEGVRTARTSYRCILRACLVRS 539
>gi|62865606 tripartite motif-containing 36 isoform 1 [Homo sapiens]
Length = 728
Score = 30.4 bits (67), Expect = 1.2
Identities = 24/101 (23%), Positives = 51/101 (50%), Gaps = 16/101 (15%)
Query: 91 SDYRVLMAEIGEDLD---------KSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEKL 141
S Y+ L ++ +D+D KS +S L LMK+ G+ +KE++ + EKL
Sbjct: 251 SAYKTLKEKLSKDIDYLIGKESQVKSQISELNLLMKETECNGERAKEEA----ITHFEKL 306
Query: 142 NLVAPDQLDLLEKCLKNIHRIDL---KTKIQKYKQSVQGAG 179
V ++ + K + + ++ L +T++++Y+ ++ G
Sbjct: 307 FEVLEERKSSVLKAIDSSKKLRLDKFQTQMEEYQGLLENNG 347
>gi|31621305 leucine-rich PPR motif-containing protein [Homo sapiens]
Length = 1394
Score = 30.4 bits (67), Expect = 1.2
Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 1/51 (1%)
Query: 90 VSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVELEK 140
V D R L+ G +++ + L+FL+++ +GK S KS L+L+ EL +
Sbjct: 1267 VDDARALLQRCGAIAEQTPIL-LLFLLRNSRKQGKASTVKSVLELIPELNE 1316
>gi|164519084 RAB GTPase activating protein 1 [Homo sapiens]
Length = 1069
Score = 29.6 bits (65), Expect = 2.1
Identities = 26/118 (22%), Positives = 51/118 (43%), Gaps = 16/118 (13%)
Query: 68 LKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMK---------- 117
LK + + + E+ + +N ++ DY+ + +++ E L+K ++ + + K
Sbjct: 912 LKEMCRRELDKAESEIKKNSSIIGDYKQICSQLSERLEKQQTANKVEIEKIRQKVDDCER 971
Query: 118 -----DYMGRGK-ISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQ 169
+ GR K IS K LD + EK L + LE + ++ + KIQ
Sbjct: 972 CREFFNKEGRVKGISSTKEVLDEDTDEEKETLKNQLREMELELAQTKLQLVEAECKIQ 1029
>gi|154813197 talpid3 protein [Homo sapiens]
Length = 1472
Score = 29.6 bits (65), Expect = 2.1
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 12/73 (16%)
Query: 26 RDVAIDVVPPNVRDLLDILRERGKLSVGDLAELLYRVRRFDLLKRILKMDR------KAV 79
+DVA+ V+P LD + E K D+ Y + + D L+ +LK K V
Sbjct: 94 KDVAVQVLP------LDKIEENNKQKANDIFISQYTMGQKDALRTVLKQKAQSMPVFKEV 147
Query: 80 ETHLLRNPHLVSD 92
+ HLL + + D
Sbjct: 148 KVHLLEDAGIEKD 160
>gi|156105697 ring finger and CCCH-type zinc finger domains 2
isoform 1 [Homo sapiens]
Length = 1191
Score = 29.3 bits (64), Expect = 2.8
Identities = 45/199 (22%), Positives = 76/199 (38%), Gaps = 31/199 (15%)
Query: 46 ERGKLSVGDLAELLYRVRRFDLLKR-----ILKMDRKAVETHLLRNPHLVSDYRVLMAEI 100
+ K S+G + +LLYR F + KR ++++ + LR H + M E
Sbjct: 233 QASKTSIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAM-EA 291
Query: 101 GEDLDKSDVSSLIF---LMKDYMGR--GKISKEKSFLDLVVEL----------EKLNLVA 145
G + SSL++ K +M K+ +SF V EL LN +
Sbjct: 292 GLRISPEQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLR 351
Query: 146 PDQLDLLEKCLKNIHRI-----DLKTKIQKYKQSVQGAGTSYRNVLQAAIQKSLKDPSNN 200
P L+LL N + L+ + K V G +N + + P++
Sbjct: 352 P-HLELLANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSK 410
Query: 201 FRMITPYAHCPDLKILGNC 219
++ + C DL+ G C
Sbjct: 411 YKT----SMCRDLRQQGGC 425
>gi|156105699 ring finger and CCCH-type zinc finger domains 2
isoform 2 [Homo sapiens]
Length = 1064
Score = 29.3 bits (64), Expect = 2.8
Identities = 45/199 (22%), Positives = 76/199 (38%), Gaps = 31/199 (15%)
Query: 46 ERGKLSVGDLAELLYRVRRFDLLKR-----ILKMDRKAVETHLLRNPHLVSDYRVLMAEI 100
+ K S+G + +LLYR F + KR ++++ + LR H + M E
Sbjct: 233 QASKTSIGHVVQLLYRASCFKVTKRDEDSSLMQLKEEFRSYEALRREHDAQIVHIAM-EA 291
Query: 101 GEDLDKSDVSSLIF---LMKDYMGR--GKISKEKSFLDLVVEL----------EKLNLVA 145
G + SSL++ K +M K+ +SF V EL LN +
Sbjct: 292 GLRISPEQWSSLLYGDLAHKSHMQSIIDKLQSPESFAKSVQELTIVLQRTGDPANLNRLR 351
Query: 146 PDQLDLLEKCLKNIHRI-----DLKTKIQKYKQSVQGAGTSYRNVLQAAIQKSLKDPSNN 200
P L+LL N + L+ + K V G +N + + P++
Sbjct: 352 P-HLELLANIDPNPDAVSPTWEQLENAMVAVKTVVHGLVDFIQNYSRKGHETPQPQPNSK 410
Query: 201 FRMITPYAHCPDLKILGNC 219
++ + C DL+ G C
Sbjct: 411 YKT----SMCRDLRQQGGC 425
>gi|116805342 human immunodeficiency virus type I enhancer binding
protein 1 [Homo sapiens]
Length = 2718
Score = 28.9 bits (63), Expect = 3.6
Identities = 12/35 (34%), Positives = 23/35 (65%)
Query: 157 KNIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAIQ 191
K IH +L+ KI++ ++ + GA S + +LQA ++
Sbjct: 5 KQIHPRNLRDKIEEAQKELNGAEVSKKEILQAGVK 39
>gi|22748787 hypothetical protein LOC126695 [Homo sapiens]
Length = 398
Score = 28.1 bits (61), Expect = 6.2
Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 15/106 (14%)
Query: 120 MGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKI--------QKY 171
MG G +S + +D+++ + L + Q+D L KC + ++ +KI Q Y
Sbjct: 229 MGSGSMSSRE--IDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDY 286
Query: 172 KQSVQGA-GTSYRNVLQAAIQKSLKDP----SNNFRMITPYAHCPD 212
Q A G R +++ + +KS P + R P A PD
Sbjct: 287 HLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPTAAAPD 332
>gi|4557663 immunoglobulin binding protein 1 [Homo sapiens]
Length = 339
Score = 27.7 bits (60), Expect = 8.1
Identities = 38/174 (21%), Positives = 70/174 (40%), Gaps = 12/174 (6%)
Query: 9 VEEALDTDEKEMLLFLCRDVAIDVVPPNVRDLLDILRERGKLSVGDLAEL-LYRVRRFDL 67
+EE TD K +L+ + A+ + N LD L+ + + L + Y V F+L
Sbjct: 68 LEEIASTDLKYLLVPAFQG-ALTMKQVNPSKRLDHLQRAREHFINYLTQCHCYHVAEFEL 126
Query: 68 LKRILKMDRKAVETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISK 127
K + + P LV+ A+I K ++ + MK + G+
Sbjct: 127 PKTMNNSAENHTANSSMAYPSLVAMASQRQAKIQRYKQKKELEHRLSAMKSAVESGQADD 186
Query: 128 EKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTS 181
E+ ++ L++ ++ L+ I ID + KI + + S + A TS
Sbjct: 187 ERVREYYLLHLQR----------WIDISLEEIESIDQEIKILRERDSSREASTS 230
>gi|4503097 casein kinase 2, alpha prime polypeptide [Homo sapiens]
Length = 350
Score = 27.7 bits (60), Expect = 8.1
Identities = 16/50 (32%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 118 DYMGRGKISKEKSFLDLVVELEKLNLVAPDQLDLLEKCLKNIHRIDLKTK 167
D +G+ + ++F + E +LV+P+ LDLL+K L+ H+ L K
Sbjct: 272 DILGQHSRKRWENF----IHSENRHLVSPEALDLLDKLLRYDHQQRLTAK 317
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 27.7 bits (60), Expect = 8.1
Identities = 24/130 (18%), Positives = 60/130 (46%), Gaps = 21/130 (16%)
Query: 79 VETHLLRNPHLVSDYRVLMAEIGEDLDKSDVSSLIFLMKDYMGRGKISKEKSFLDLVVEL 138
++T L +S + ++E+ ++++K++ L + ++E L+ ++L
Sbjct: 435 LDTQLEDKEKKISAAQTRLSELHDEIEKAEQQIL-----------RATEEFKQLEEAIQL 483
Query: 139 EKLNLVAPD--------QLDLLEKCLKNIHRIDLKTKIQKYKQSVQGAGTSYRNVLQAAI 190
+K++ D +L L+ K + +DL+ +++K KQ + G +++ A
Sbjct: 484 KKISEAGKDLLYKQLSGRLQLVNKLRQEA--LDLELQMEKQKQEIAGKQKEIKDLQIAID 541
Query: 191 QKSLKDPSNN 200
KDP ++
Sbjct: 542 SLDSKDPKHS 551
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,390,085
Number of Sequences: 37866
Number of extensions: 281626
Number of successful extensions: 851
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 819
Number of HSP's gapped (non-prelim): 34
length of query: 221
length of database: 18,247,518
effective HSP length: 98
effective length of query: 123
effective length of database: 14,536,650
effective search space: 1788007950
effective search space used: 1788007950
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.