Search of human proteins with 187607445

Search of human proteins with 187607445

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|187607445 hypothetical protein LOC79137 [Homo sapiens]
         (543 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|187607445 hypothetical protein LOC79137 [Homo sapiens]            1082   0.0  
gi|30023820 hypothetical protein LOC162427 [Homo sapiens]             232   7e-61
gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens]    173   3e-43
gi|21361617 hypothetical protein LOC54463 isoform 2 [Homo sapiens]    145   7e-35
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    54   3e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          49   2e-05
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          49   2e-05
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          49   2e-05
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]     48   3e-05
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]     48   3e-05
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]            47   3e-05
gi|55741677 SET domain containing 1A [Homo sapiens]                    46   8e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    46   8e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    46   8e-05
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         45   1e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   3e-04
gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH dom...    44   5e-04
gi|153792074 proline rich 12 [Homo sapiens]                            44   5e-04
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         43   6e-04
gi|223633941 hypothetical protein LOC389730 [Homo sapiens]             42   0.001
gi|91206406 hypothetical protein LOC642265 [Homo sapiens]              42   0.001
gi|146231958 hypothetical protein LOC647060 [Homo sapiens]             42   0.001
gi|24308007 ADP-ribosylation factor-like 6 interacting protein [...    42   0.001
gi|169174618 PREDICTED: family with sequence similarity 75, memb...    42   0.001
gi|239743732 PREDICTED: family with sequence similarity 75, memb...    42   0.001
gi|153791826 hypothetical protein LOC26165 [Homo sapiens]              42   0.001
gi|133892686 hypothetical protein LOC727830 [Homo sapiens]             42   0.001
gi|165377334 hypothetical protein LOC727905 [Homo sapiens]             42   0.001
gi|33356148 formin-like 1 [Homo sapiens]                               41   0.002
gi|83367077 mucin 16 [Homo sapiens]                                    41   0.003

>gi|187607445 hypothetical protein LOC79137 [Homo sapiens]
          Length = 543

 Score = 1082 bits (2797), Expect = 0.0
 Identities = 543/543 (100%), Positives = 543/543 (100%)

Query: 1   MASGGGGGNTGAGGGPGMGLSLGLGLGLSLGMSEATSEAEEEAATAEAVGRLATTLWLRL 60
           MASGGGGGNTGAGGGPGMGLSLGLGLGLSLGMSEATSEAEEEAATAEAVGRLATTLWLRL
Sbjct: 1   MASGGGGGNTGAGGGPGMGLSLGLGLGLSLGMSEATSEAEEEAATAEAVGRLATTLWLRL 60

Query: 61  RGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLW 120
           RGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLW
Sbjct: 61  RGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLW 120

Query: 121 QPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKR 180
           QPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKR
Sbjct: 121 QPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKR 180

Query: 181 QNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLL 240
           QNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLL
Sbjct: 181 QNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLL 240

Query: 241 MQLDYSMKAEANALHHKHDKRKRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTA 300
           MQLDYSMKAEANALHHKHDKRKRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTA
Sbjct: 241 MQLDYSMKAEANALHHKHDKRKRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTA 300

Query: 301 LALAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEG 360
           LALAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEG
Sbjct: 301 LALAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEG 360

Query: 361 EEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPD 420
           EEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPD
Sbjct: 361 EEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPD 420

Query: 421 GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA 480
           GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA
Sbjct: 421 GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA 480

Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAV 540
           PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAV
Sbjct: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAV 540

Query: 541 AEP 543
           AEP
Sbjct: 541 AEP 543


>gi|30023820 hypothetical protein LOC162427 [Homo sapiens]
          Length = 466

 Score =  232 bits (591), Expect = 7e-61
 Identities = 154/451 (34%), Positives = 231/451 (51%), Gaps = 49/451 (10%)

Query: 63  WEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLWQP 122
           +E +L+  Q  LVWE+P  S +    LN  FW  + +SLR  FLL+  L+    +D W+ 
Sbjct: 49  YEPLLSRVQAALVWERPARSALWCLGLNAAFWFFALTSLRLVFLLAFGLMIIVCIDQWKN 108

Query: 123 RFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKRQN 182
           +  P++    P+   ++S G      P LLSVPELC ++AE W++  I ++ +L +K+QN
Sbjct: 109 KIWPEIKVPRPDALDNESWGF---VHPRLLSVPELCHHVAEVWVSGTIFIRNVLLFKKQN 165

Query: 183 PAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLLMQ 242
           P +FC+  C     LAVLG YVPG+++SY++L+++++WPL VYH L  R Y RL+P L +
Sbjct: 166 PGKFCLLSCGILTFLAVLGRYVPGLLLSYLMLVTVMMWPLAVYHRLWDRAYVRLKPALQR 225

Query: 243 LDYSMKAEANALHHKHDKRKRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALA 302
           LD+S++    +   +   R+R          E   +  S+SE ELA F P +D    A  
Sbjct: 226 LDFSVRGYMMSKQRERQLRRRALH------PERAMDNHSDSEEELAAFCPQLDDSTVARE 279

Query: 303 LAITDSELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEE 362
           LAITDSE SD E S  ++G F++SR  TP LT+ SEDLD  S   +PEE+ +RDL +   
Sbjct: 280 LAITDSEHSDAEVSCTDNGTFNLSRGQTP-LTEGSEDLDGHS---DPEESFARDLPDFPS 335

Query: 363 GELAPP------EDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAG 416
             + P       +  +G P  + R    +EE +   A+++                  A 
Sbjct: 336 INMDPAGLDDEDDTSIGMPSLMYRSPPGAEEPQAPPASRDE-----------------AA 378

Query: 417 SPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVG-SDPAPSPSILPPVPQDSP 475
            P   +   P G         ++  L +L       L L G S P PS +   P  + + 
Sbjct: 379 LPELLLGALPVG-------SNLTSNLASLVSQGMIQLALSGASQPGPSGA---PAQRATR 428

Query: 476 QPLPAPEEEEALTTE--DFELLDQGELEQLN 504
             L +P  +     E  DFELLDQ EL QL+
Sbjct: 429 GFLRSPSSDLDTDAEGDDFELLDQSELSQLD 459


>gi|77917617 hypothetical protein LOC54463 isoform 1 [Homo sapiens]
          Length = 497

 Score =  173 bits (439), Expect = 3e-43
 Identities = 143/498 (28%), Positives = 232/498 (46%), Gaps = 84/498 (16%)

Query: 23  GLGLGLSLGMSEATSEAEEEAATAEAVGRLATTLWLRLRGWEAVLAAAQRLLVWEKPLHS 82
           G   G  L + EA   A   AA    +G     LWL  R        A  LL W++PL S
Sbjct: 48  GAAEGAGLQVEEAAGRAA--AAVTWLLGE--PVLWLGCR--------ADELLSWKRPLRS 95

Query: 83  LVTAAALNGLFWLLSSSSLRPFFLLSVSLLAYFLLDLWQPRFLPDVSASSPEEPHSDSEG 142
           L+   A N LFW L+ +  R + L+SV +L   ++ + +   L     +      S+S  
Sbjct: 96  LLGFVAANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVLSRTRGAQLWRSLSESWE 155

Query: 143 AGSGARPHLLSVPELCRYLAESWLTFQIHLQELLQYKRQNPAQFCVRVCSGCAVLAVLGH 202
               ++P     P L   +AESW+ F I LQE+  +K+Q+P +FC+ VCS C    +LG 
Sbjct: 156 V-INSKPD--ERPRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGS 212

Query: 203 YVPGIMISYIVLLSILLWPLVVYHELIQRMYTRLEPLLMQLDYSMKAEANALHHKHDKRK 262
           Y+PG+++SY++LL   L PL   +++ Q++Y++++ +L++LD+ +    N       ++K
Sbjct: 213 YIPGVILSYLLLLCAFLCPLFKCNDIGQKIYSKIKSVLLKLDFGIGEYIN-------QKK 265

Query: 263 RQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGG 322
           R+   A     +     + +SE + +   P + +   A  L+++D+++S  E S  ++G 
Sbjct: 266 RERSEA-----DKEKSHKDDSELDFSALCPKISLTVAAKELSVSDTDVS--EVSWTDNGT 318

Query: 323 FSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDL----------GEGEEGELAPPEDLL 372
           F++S   TPQ TD S+DLD+ S     EE  SRDL          G  +E EL+     L
Sbjct: 319 FNLSEGYTPQ-TDTSDDLDRPS-----EEVFSRDLSDFPSLENGMGTNDEDELS-----L 367

Query: 373 GRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVET 432
           G P  L R+    +         ++   L+ PL+   T                   +  
Sbjct: 368 GLPTELKRKKEQLDSGHRPSKETQSAAGLTLPLNSDQTFH----------------LMSN 411

Query: 433 LSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEE-EALTTED 491
           L+ + ++  +T                 A     L  V Q   Q  P PEE+ +    +D
Sbjct: 412 LAGDVITAAVT-----------------AAIKDQLEGVQQALSQAAPIPEEDTDTEEGDD 454

Query: 492 FELLDQGELEQLNAELGL 509
           FELLDQ EL+Q+ +ELGL
Sbjct: 455 FELLDQSELDQIESELGL 472


>gi|21361617 hypothetical protein LOC54463 isoform 2 [Homo sapiens]
          Length = 356

 Score =  145 bits (367), Expect = 7e-35
 Identities = 107/366 (29%), Positives = 178/366 (48%), Gaps = 69/366 (18%)

Query: 155 PELCRYLAESWLTFQIHLQELLQYKRQNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVL 214
           P L   +AESW+ F I LQE+  +K+Q+P +FC+ VCS C    +LG Y+PG+++SY++L
Sbjct: 24  PRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLL 83

Query: 215 LSILLWPLVVYHELIQRMYTRLEPLLMQLDYSMKAEANALHHKHDKRKRQGKNAPPGGDE 274
           L   L PL   +++ Q++Y++++ +L++LD+ +    N       ++KR+   A     +
Sbjct: 84  LCAFLCPLFKCNDIGQKIYSKIKSVLLKLDFGIGEYIN-------QKKRERSEA-----D 131

Query: 275 PLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATTPQLT 334
                + +SE + +   P + +   A  L+++D+++S  E S  ++G F++S   TPQ T
Sbjct: 132 KEKSHKDDSELDFSALCPKISLTVAAKELSVSDTDVS--EVSWTDNGTFNLSEGYTPQ-T 188

Query: 335 DVSEDLDQQSLPSEPEETLSRDL----------GEGEEGELAPPEDLLGRPQALSRQALD 384
           D S+DLD+ S     EE  SRDL          G  +E EL+     LG P  L R+   
Sbjct: 189 DTSDDLDRPS-----EEVFSRDLSDFPSLENGMGTNDEDELS-----LGLPTELKRKKEQ 238

Query: 385 SEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTA 444
            +         ++   L+ PL+   T                   +  L+ + ++  +T 
Sbjct: 239 LDSGHRPSKETQSAAGLTLPLNSDQTFH----------------LMSNLAGDVITAAVT- 281

Query: 445 LPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEE-EALTTEDFELLDQGELEQL 503
                           A     L  V Q   Q  P PEE+ +    +DFELLDQ EL+Q+
Sbjct: 282 ----------------AAIKDQLEGVQQALSQAAPIPEEDTDTEEGDDFELLDQSELDQI 325

Query: 504 NAELGL 509
            +ELGL
Sbjct: 326 ESELGL 331


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 74/269 (27%), Positives = 102/269 (37%), Gaps = 29/269 (10%)

Query: 268 APPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSR 327
           +PP  + PL+     S       SP+   +++  + A+        EAS L S  F  S 
Sbjct: 495 SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPL-SPPFEESP 553

Query: 328 ATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPP--EDLLGRPQALSRQALDS 385
            + P           + LP+ P    SR     EE  ++PP  E  +  P   SR     
Sbjct: 554 LSPPP----------EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPF 603

Query: 386 EE-------EEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETV 438
           EE       EE  ++      RLS P        +    PP+    SP   V  LSP  V
Sbjct: 604 EESPLSPPPEESPLSPPPEASRLSPP-----PEDSPMSPPPEESPMSPPPEVSRLSPLPV 658

Query: 439 SGGLTALP--GTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLD 496
              L+  P    LSPP     + P P  S L P P+DSP   P PE+  A    +  L+ 
Sbjct: 659 VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS-PPPEDSPASPPPEDSLMS 717

Query: 497 QGELEQLNAELGLEPETPPKPPDAPPLGP 525
               E     L  EP+  P+  + P L P
Sbjct: 718 LPLEESPLLPLPEEPQLCPR-SEGPHLSP 745



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 61/254 (24%), Positives = 86/254 (33%), Gaps = 31/254 (12%)

Query: 314 EASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETL------SRDLGEGEEGELAP 367
           EAS L      +  +  P+   +S  L++  L   PEE+       S      EE  L+P
Sbjct: 463 EASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP 522

Query: 368 PEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPG 427
           PE+    P       L    E   ++       LS P   + T       PP+  + SP 
Sbjct: 523 PEE--SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPT-----SPPPEASRLSPP 575

Query: 428 GPVETLSPETVSGGLTALP-----------GTLSPPLCLVGSDPAPSPSILPPVPQDSPQ 476
                +SP      ++  P             LSPP       P P  S L P P+DSP 
Sbjct: 576 PEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM 635

Query: 477 PLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPP-------KPPDAPPLGPDIHS 529
             P  E   +   E   L     + +L+      P +PP        PP+A  L P    
Sbjct: 636 SPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPED 695

Query: 530 LVQSDQEAQAVAEP 543
              S     + A P
Sbjct: 696 SPTSPPPEDSPASP 709



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 51/190 (26%), Positives = 71/190 (37%), Gaps = 19/190 (10%)

Query: 346 PSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPL 405
           P+ P    SR     EE   +P  + L   + L    L    EE  ++        SSP 
Sbjct: 457 PTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE----SSPF 512

Query: 406 HFVNTHFNGAGSPPDGVKCSPGGPVET-LSPETVSGGLTAL--PGTLSPPLCLVGSDPAP 462
             +        SPP+    SP   +ET LSP   +  L+       LSPP   + + P P
Sbjct: 513 SPLE---ESPLSPPEESPPSPA--LETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP 567

Query: 463 SPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPP------- 515
             S L P P++SP   P  E   +   E   L    E   L+      P +PP       
Sbjct: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS 627

Query: 516 KPPDAPPLGP 525
            PP+  P+ P
Sbjct: 628 PPPEDSPMSP 637



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 37/123 (30%), Positives = 44/123 (35%), Gaps = 15/123 (12%)

Query: 418 PPDGVKCSPGGPVETLSPETVSGGLTALPGT--LSPPLCLVGSDPAPSPSILPPVPQDSP 475
           PP+    SP      LSP       + LP    LS PL      P P  S L P P+ SP
Sbjct: 452 PPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSP 511

Query: 476 ------QPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPP-------KPPDAPP 522
                  PL  PEE       +  L    E   L+      P +PP        PP+A  
Sbjct: 512 FSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASR 571

Query: 523 LGP 525
           L P
Sbjct: 572 LSP 574



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 33/105 (31%), Positives = 43/105 (40%), Gaps = 13/105 (12%)

Query: 418  PPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPL--CLVGSDPAPSPSILPPVPQDSP 475
            PP  +  SPG PV   SP  +      LP   SP L   LV  +  PS    P +P   P
Sbjct: 997  PPMILPPSPGSPVGPASPILME----PLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVP 1052

Query: 476  QPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDA 520
             PL    +   ++       D+ EL ++  E   EPE P   P A
Sbjct: 1053 SPLSPIGKVVGVS-------DEAELHEMETEKVSEPECPALEPSA 1090



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 74/308 (24%), Positives = 106/308 (34%), Gaps = 49/308 (15%)

Query: 230  QRMYTRLEPLLMQLDYSMKAEANALHH-KHDKRKRQGKNAPPGGDEPLAETESESEAELA 288
            QR   RL  LL++     + + N L   K       G   PPG     AE  S +  +L+
Sbjct: 2680 QRQRQRLRELLIR----QQIQRNTLRQEKETAAAAAGAVGPPGSWG--AEPSSPAFEQLS 2733

Query: 289  -GFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATT---PQLTDVSEDLDQQS 344
             G +P    +  +  + +  S+LS     IL  G F      +   P  T  S D++ + 
Sbjct: 2734 RGQTPFAGTQDKSSLVGLPPSKLS---GPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQ 2790

Query: 345  LPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLL---RL 401
            L    +    R    G        + L  + QA +  ++         +     L    L
Sbjct: 2791 LVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQAL 2850

Query: 402  SSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLS-PETVSGGLTALPGTLSPPLCLVGSDP 460
             SPL  ++T   G G P  G    P GP + +     V  GL              G   
Sbjct: 2851 GSPLAGISTRLPGPGEPVPG----PAGPAQFIELRHNVQKGL--------------GPGG 2892

Query: 461  APSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDA 520
             P P   PP     P+  P  E+   L  E    L         A  GL P+ P  PP A
Sbjct: 2893 TPFPGQGPP---QRPRFYPVSEDPHRLAPEGLRGL---------AVSGLPPQKPSAPP-A 2939

Query: 521  PPLGPDIH 528
            P L   +H
Sbjct: 2940 PELNNSLH 2947



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 2/84 (2%)

Query: 460 PAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPD 519
           P P  S L P P++SP     P E   L+    EL      E L+    LE      PP+
Sbjct: 442 PPPEESPLSPPPEESPTS--PPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499

Query: 520 APPLGPDIHSLVQSDQEAQAVAEP 543
             PL P   S   S  E   ++ P
Sbjct: 500 ESPLSPPPESSPFSPLEESPLSPP 523



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 39/134 (29%), Positives = 50/134 (37%), Gaps = 27/134 (20%)

Query: 418  PPDGVKCSPGGP---VETLSPETVSGGL----TALPG-TLSPPLCLVGSDPAPSPSILPP 469
            P  G    PGG    +E  SP+T    L      LPG TL   L            IL  
Sbjct: 4830 PKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQL-----------DILSL 4878

Query: 470  VPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIHS 529
            + Q+SP P P  +        + ++       QL+A    EP  PP P    P  P    
Sbjct: 4879 LKQESPAPEPPTQHSYTYNVSNLDV------RQLSAPPPEEPSPPPSPLAPSPASPPTEP 4932

Query: 530  LVQSDQEAQAVAEP 543
            LV+   E   +AEP
Sbjct: 4933 LVELPTE--PLAEP 4944



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 32/104 (30%), Positives = 45/104 (43%), Gaps = 13/104 (12%)

Query: 449 LSPPLCLVGSDPAPSPSILPPVPQDSP-QPLP------APEEEEALT--TEDFELLDQGE 499
           LSPP     + P P  S L P P++ P  PLP       P EE  L+   E+  L    E
Sbjct: 449 LSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPE 508

Query: 500 LEQLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAVAEP 543
               +    LE E+P  PP+  P  P + + +    EA  ++ P
Sbjct: 509 SSPFSP---LE-ESPLSPPEESPPSPALETPLSPPPEASPLSPP 548



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 66/223 (29%), Positives = 80/223 (35%), Gaps = 37/223 (16%)

Query: 331 PQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPED---LLGRPQALSRQALDSEE 387
           PQL   SE       P EP  +        EE  L+P  +   L  +P+     A+  E 
Sbjct: 732 PQLCPRSEGPHLSPRPEEPHLS-----PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEP 786

Query: 388 EEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVET-LSPETVSGGLTALP 446
                A    L      LH          SP     C    P E+ LSP++    L+  P
Sbjct: 787 HLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846

Query: 447 --GTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEE--------EEALTTEDFE--L 494
               LSP L      P  SP   P  P + P   PAPEE        E +L+    E  L
Sbjct: 847 EESHLSPEL----EKPPLSPR--PEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPAL 900

Query: 495 LDQGE--LEQLNAELGLEPETPPK------PPDA--PPLGPDI 527
            + GE  L  L  EL L P   P       PPD   PPL P I
Sbjct: 901 SEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII 943



 Score = 29.3 bits (64), Expect = 9.6
 Identities = 19/69 (27%), Positives = 23/69 (33%), Gaps = 5/69 (7%)

Query: 414  GAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGT-----LSPPLCLVGSDPAPSPSILP 468
            GAG  P  +   P G +    P          PGT        P+          PS+ P
Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKP 2549

Query: 469  PVPQDSPQP 477
            PVPQ    P
Sbjct: 2550 PVPQPGLPP 2558


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 62/265 (23%), Positives = 101/265 (38%), Gaps = 44/265 (16%)

Query: 262 KRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESG 321
           +  G+N+P        ++++E+  + A       VK+ A +   ++    ++ AS  E  
Sbjct: 53  RSSGRNSPSAASTSSNDSKAETVKKSAK-----KVKEEASSPLKSNKRQREKVASDTEEA 107

Query: 322 GFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPE-DLLGRPQALSR 380
             + S+ T  Q      ++ + + PSE E   S      +EG   P + D   R  + S 
Sbjct: 108 DRTSSKKTKTQ------EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI 161

Query: 381 QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSG 440
            +    E + D +A++ +L+   P          A   P GV  +P              
Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPP----------ALQAPTGVTPAPS------------- 198

Query: 441 GLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGEL 500
             +A PGT   P       P P+PS     PQ SP    AP + +A T        Q + 
Sbjct: 199 --SAPPGTPQLPT------PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ-QA 249

Query: 501 EQLNAELGLEPETPPKPPDAPPLGP 525
             L+ +    P  PP P   PPL P
Sbjct: 250 PALHPQRPPSPHPPPHPSPHPPLQP 274



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 34/125 (27%)

Query: 415 AGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDP--APSPSILPP--- 469
           A  PP G+      P     P  V GG    P  ++PP C   S P   P  S  PP   
Sbjct: 464 ASHPPTGLHQVAPQPPFAQHP-FVPGG----PPPITPPTCPSTSTPPAGPGTSAQPPCSG 518

Query: 470 -------VPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
                  +   S  PLP  + +E       E LD  E          EPE+PP PP +P 
Sbjct: 519 AAASGGSIAGGSSCPLPTVQIKE-------EALDDAE----------EPESPPPPPRSPS 561

Query: 523 LGPDI 527
             P +
Sbjct: 562 PEPTV 566



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 11/102 (10%)

Query: 429 PVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSIL--------PPVPQDSPQPLPA 480
           P   L P T S G  + P    PPL   G  P P P  L        P  PQ    P  A
Sbjct: 268 PHPPLQPLTGSAGQPSAPSHAQPPLH--GQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQA 324

Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
            + +  L T          L+   ++  L+ + PP+    PP
Sbjct: 325 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 366


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 62/265 (23%), Positives = 101/265 (38%), Gaps = 44/265 (16%)

Query: 262 KRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESG 321
           +  G+N+P        ++++E+  + A       VK+ A +   ++    ++ AS  E  
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAK-----KVKEEASSPLKSNKRQREKVASDTEEA 661

Query: 322 GFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPE-DLLGRPQALSR 380
             + S+ T  Q      ++ + + PSE E   S      +EG   P + D   R  + S 
Sbjct: 662 DRTSSKKTKTQ------EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI 715

Query: 381 QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSG 440
            +    E + D +A++ +L+   P          A   P GV  +P              
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPP----------ALQAPTGVTPAPS------------- 752

Query: 441 GLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGEL 500
             +A PGT   P       P P+PS     PQ SP    AP + +A T        Q + 
Sbjct: 753 --SAPPGTPQLPT------PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ-QA 803

Query: 501 EQLNAELGLEPETPPKPPDAPPLGP 525
             L+ +    P  PP P   PPL P
Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQP 828



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 34/125 (27%)

Query: 415  AGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDP--APSPSILPP--- 469
            A  PP G+      P     P  V GG    P  ++PP C   S P   P  S  PP   
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHP-FVPGG----PPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072

Query: 470  -------VPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
                   +   S  PLP  + +E       E LD  E          EPE+PP PP +P 
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKE-------EALDDAE----------EPESPPPPPRSPS 1115

Query: 523  LGPDI 527
              P +
Sbjct: 1116 PEPTV 1120



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 11/102 (10%)

Query: 429 PVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSIL--------PPVPQDSPQPLPA 480
           P   L P T S G  + P    PPL   G  P P P  L        P  PQ    P  A
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQPPLH--GQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQA 878

Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
            + +  L T          L+   ++  L+ + PP+    PP
Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 62/265 (23%), Positives = 101/265 (38%), Gaps = 44/265 (16%)

Query: 262 KRQGKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESG 321
           +  G+N+P        ++++E+  + A       VK+ A +   ++    ++ AS  E  
Sbjct: 607 RSSGRNSPSAASTSSNDSKAETVKKSAK-----KVKEEASSPLKSNKRQREKVASDTEEA 661

Query: 322 GFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPE-DLLGRPQALSR 380
             + S+ T  Q      ++ + + PSE E   S      +EG   P + D   R  + S 
Sbjct: 662 DRTSSKKTKTQ------EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSI 715

Query: 381 QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSG 440
            +    E + D +A++ +L+   P          A   P GV  +P              
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPP----------ALQAPTGVTPAPS------------- 752

Query: 441 GLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGEL 500
             +A PGT   P       P P+PS     PQ SP    AP + +A T        Q + 
Sbjct: 753 --SAPPGTPQLPT------PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ-QA 803

Query: 501 EQLNAELGLEPETPPKPPDAPPLGP 525
             L+ +    P  PP P   PPL P
Sbjct: 804 PALHPQRPPSPHPPPHPSPHPPLQP 828



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 34/125 (27%)

Query: 415  AGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDP--APSPSILPP--- 469
            A  PP G+      P     P  V GG    P  ++PP C   S P   P  S  PP   
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHP-FVPGG----PPPITPPTCPSTSTPPAGPGTSAQPPCSG 1072

Query: 470  -------VPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
                   +   S  PLP  + +E       E LD  E          EPE+PP PP +P 
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKE-------EALDDAE----------EPESPPPPPRSPS 1115

Query: 523  LGPDI 527
              P +
Sbjct: 1116 PEPTV 1120



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 11/102 (10%)

Query: 429 PVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSIL--------PPVPQDSPQPLPA 480
           P   L P T S G  + P    PPL   G  P P P  L        P  PQ    P  A
Sbjct: 822 PHPPLQPLTGSAGQPSAPSHAQPPLH--GQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQA 878

Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPP 522
            + +  L T          L+   ++  L+ + PP+    PP
Sbjct: 879 SQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920


>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
          Length = 374

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 38/107 (35%), Positives = 47/107 (43%), Gaps = 16/107 (14%)

Query: 427 GGPVETLSPETVSGGLTALP------GTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA 480
           G P    +P   +  + A P      G   PP  L G D  P   +LPP P   P P+  
Sbjct: 58  GRPSPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPP--PPPPVLL 115

Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDI 527
           P EEEA       L+   +LEQL+    L P  PP PP AP  GP +
Sbjct: 116 PSEEEAPAPMGASLI--ADLEQLH----LSP--PPPPPQAPAEGPSV 154


>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
          Length = 373

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 38/107 (35%), Positives = 47/107 (43%), Gaps = 16/107 (14%)

Query: 427 GGPVETLSPETVSGGLTALP------GTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPA 480
           G P    +P   +  + A P      G   PP  L G D  P   +LPP P   P P+  
Sbjct: 58  GRPSPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPP--PPPPVLL 115

Query: 481 PEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDI 527
           P EEEA       L+   +LEQL+    L P  PP PP AP  GP +
Sbjct: 116 PSEEEAPAPMGASLI--ADLEQLH----LSP--PPPPPQAPAEGPSV 154


>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
          Length = 1444

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 26/268 (9%)

Query: 270 PGGDEPL-AETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRA 328
           P  ++PL AET + S  + AG      V +    +  +   LS E  + LE         
Sbjct: 536 PEEEKPLGAETSAASVPKKAGLEDAKAVPEAPGTVECSKG-LSQEPGAHLEE-------K 587

Query: 329 TTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEE 388
            TP+ +  S+ L++      PE+ +     EG E        L   P+A +   L  E +
Sbjct: 588 KTPESSLSSQHLNELEKRPNPEKVVE----EGREAGEMESSTLQESPRARAEAVLLHEMD 643

Query: 389 EEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLS-----PETVSGGLT 443
           E+D+A       +   L  + +    +  PP  +K SP  P+   S     P    G L 
Sbjct: 644 EDDLANALIWPEIQQELKIIESEEELSSLPPPALKTSPIQPILESSLGPFIPSEPPGSLP 703

Query: 444 --ALPGTLSPPLCLVGSDPA--PSPSILPPVPQDSPQPLPAPEEEEA----LTTEDFELL 495
             + P  +S PL +   DPA   +        ++ P+P      + A    L    FE  
Sbjct: 704 CGSFPAPVSTPLEVWTRDPANQSTQGASTAASREKPEPEQGLHPDLASLAPLEIVPFEKA 763

Query: 496 DQGELEQLNAELGLEPETPPKPPDAPPL 523
                 ++     L P  PP PP   PL
Sbjct: 764 SPQATVEVGGPGNLSPPLPPAPPPPTPL 791


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 64/265 (24%), Positives = 95/265 (35%), Gaps = 30/265 (11%)

Query: 269  PPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRA 328
            PP  DE   +T+ +     A  S   +  + + +    + +  DEE    E      +  
Sbjct: 941  PPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREE-----AVD 995

Query: 329  TTPQLTDVSEDLDQQSLPSEPEETLSRDLGEG------EEGELAPPEDLLGRPQALSRQA 382
            TT + T+VS+  D++S  S      +   GE       E    +          + S  +
Sbjct: 996  TTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSS 1055

Query: 383  LDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGG- 441
              SE   ED   +E    L S           A  PP  V      PVE   PE V+G  
Sbjct: 1056 SSSESSSEDEEEEERPAALPS-----------ASPPPREVPVPTPAPVEVPVPERVAGSP 1104

Query: 442  LTALPGTLSPPLCLVG--SDPAPSPSILPPVPQDSPQ-PLPAPEEEEALTTEDFELLDQG 498
            +T LP   + P    G   +  PS  + PP P   P  P P P+E     +    LL   
Sbjct: 1105 VTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDER---PSSPIPLLPPP 1161

Query: 499  ELEQLNAEL-GLEPETPPKPPDAPP 522
            +  +       +E    P+PP A P
Sbjct: 1162 KKRRKTVSFSAIEVVPAPEPPPATP 1186



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 49/197 (24%), Positives = 68/197 (34%), Gaps = 22/197 (11%)

Query: 344  SLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSR-----QALDSEEEEEDVAAKETL 398
            +L SE EE       E +E +    E+   R +A+       +  D E+EE D ++K +L
Sbjct: 960  ALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSL 1019

Query: 399  LRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGL--------TALPGTLS 450
               S   +   +    + S       S      + S  + S            ALP    
Sbjct: 1020 YADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASP 1079

Query: 451  PPLCLVGSDPAPSPSILPPVPQDSP-QPLPAPEEEEALTTEDFELLDQGELEQLNAELGL 509
            PP  +    PAP    +P     SP  PLP  E   A           G  E+      L
Sbjct: 1080 PPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPA--------GPTEESPPSAPL 1131

Query: 510  EPETPPKPPDAPPLGPD 526
             P  PP  P AP   PD
Sbjct: 1132 RPPEPPAGPPAPAPRPD 1148



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 66/290 (22%), Positives = 95/290 (32%), Gaps = 30/290 (10%)

Query: 262 KRQGKNAPPGGDEPLAETESES-EAELAGFSPVVDVKKTALALAITDSELSDEEASILES 320
           +R  +  PPG   P AE  +E        + P    + T        SE    E    E 
Sbjct: 385 RRATREEPPGA--PFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPP--EP 440

Query: 321 GGFSVSRATTPQLTDVSEDLDQQSLPSEPE-------ETLSRDLGEGEEGELAPPEDLLG 373
           GG       +P+     E++     P+ P        ET +  +   +   L    ++L 
Sbjct: 441 GGGGGGGGPSPE----REEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLL 496

Query: 374 RPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPP-------DGVKCSP 426
           + Q      L S+ EEE+  +   L    +     +   +G  +PP       D      
Sbjct: 497 KEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPTGS 556

Query: 427 GGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEA 486
           G P  T      +G   A P +    + +   D   SP   P  PQ  P P P P     
Sbjct: 557 GEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPPPPPPPPP 616

Query: 487 LTTEDFELLDQGELEQLNAE-LGLEPETPPKP--PDAPPLGPDIHSLVQS 533
                   L  G      A  L   P+ PP P  P  PP  P I+  V S
Sbjct: 617 YLAS----LPLGYPPHQPAYLLPPRPDGPPPPEYPPPPPPPPHIYDFVNS 662



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 41/168 (24%), Positives = 57/168 (33%), Gaps = 9/168 (5%)

Query: 360  GEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPP 419
            G E +LA   DL   P      AL + E+ E     +   R    L  +    N A +  
Sbjct: 1248 GTEVDLAVLADLALTPARRGLPALPAVEDSEATETSDEAERPRPLLSHILLEHNYALA-- 1305

Query: 420  DGVKCSPGGP-VETLSPETVSGGLTALPG--TLSPPLCLVGSDPAPSPSILPPVPQDSPQ 476
              VK +P  P +    P      L + P    L  P  +V     P P  L    ++  +
Sbjct: 1306 --VKPTPPAPALRPPEPVPAPAALFSSPADEVLEAPEVVVAEAEEPKPQQLQQQREEGEE 1363

Query: 477  PLPAPEEEEALTTEDFELLDQGE--LEQLNAELGLEPETPPKPPDAPP 522
                  EEE   + D      GE  L + +         PP PP  PP
Sbjct: 1364 EGEEEGEEEEEESSDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPP 1411


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 79/328 (24%), Positives = 129/328 (39%), Gaps = 35/328 (10%)

Query: 222 LVVYHELIQRMY--TRLEPLLMQLDYSMKA--EANALHHKHDKRKRQGKNAPPGGDEPLA 277
           L V H+ ++ +   T++E    +++ ++ A  E  A+  K +K++          +E   
Sbjct: 446 LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE--------AAEEKEE 497

Query: 278 ETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATTPQLTDVS 337
           E E+E E   A  SPV   K TA  +   + E  +EE    E            +  D  
Sbjct: 498 EPEAEEEEVAAKKSPV---KATAPEVKEEEGEKEEEEGQEEE------------EEEDEG 542

Query: 338 EDLDQ-QSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKE 396
              DQ +   SE E +  ++ GE EEGE     +     +A +++    EE+ E+VA KE
Sbjct: 543 AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAE---GEEAEAKEEKKVEEKSEEVATKE 599

Query: 397 TLLRLSSPLHFVNTHFNGAGSPPD--GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLC 454
            L+  +              SP +  G    P  PVE      V        G    P  
Sbjct: 600 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 659

Query: 455 LVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETP 514
            V  +   SP    PV + +  P+P    EEA +  +    +Q E E+   +   + E  
Sbjct: 660 PV-EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV 718

Query: 515 PKPPDAPPLGPDIHSLVQSDQEAQAVAE 542
            K  + P   P+     +S  + +AVAE
Sbjct: 719 EKKEEKPKDVPE-KKKAESPVKEEAVAE 745


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 79/328 (24%), Positives = 129/328 (39%), Gaps = 35/328 (10%)

Query: 222 LVVYHELIQRMY--TRLEPLLMQLDYSMKA--EANALHHKHDKRKRQGKNAPPGGDEPLA 277
           L V H+ ++ +   T++E    +++ ++ A  E  A+  K +K++          +E   
Sbjct: 70  LKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE--------AAEEKEE 121

Query: 278 ETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRATTPQLTDVS 337
           E E+E E   A  SPV   K TA  +   + E  +EE    E            +  D  
Sbjct: 122 EPEAEEEEVAAKKSPV---KATAPEVKEEEGEKEEEEGQEEE------------EEEDEG 166

Query: 338 EDLDQ-QSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKE 396
              DQ +   SE E +  ++ GE EEGE     +     +A +++    EE+ E+VA KE
Sbjct: 167 AKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAE---GEEAEAKEEKKVEEKSEEVATKE 223

Query: 397 TLLRLSSPLHFVNTHFNGAGSPPD--GVKCSPGGPVETLSPETVSGGLTALPGTLSPPLC 454
            L+  +              SP +  G    P  PVE      V        G    P  
Sbjct: 224 ELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKS 283

Query: 455 LVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETP 514
            V  +   SP    PV + +  P+P    EEA +  +    +Q E E+   +   + E  
Sbjct: 284 PV-EEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKV 342

Query: 515 PKPPDAPPLGPDIHSLVQSDQEAQAVAE 542
            K  + P   P+     +S  + +AVAE
Sbjct: 343 EKKEEKPKDVPE-KKKAESPVKEEAVAE 369


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 73/270 (27%), Positives = 114/270 (42%), Gaps = 37/270 (13%)

Query: 274 EPLAETESESEAELAGFSPVVDVKKTALALA-ITDSELSDEEASILESGGFSVSRATTPQ 332
           +P+ ++ S + A L   +   ++  TA  LA +  S   + EAS + +GG ++S +T   
Sbjct: 336 DPITDSGSGAGAFL-DIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTLSMSTENP 394

Query: 333 LTDVSEDLDQQ----SLPSEPEETLSRDLGEGEEGELAPPE-DLLGRPQALSRQAL--DS 385
              V+   D +    +  +   E L+   GE E   +AP E DL    Q+L  +A    S
Sbjct: 395 EEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPS 454

Query: 386 EEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVE-TLSPETVSGGLTA 444
            E+    AA  T + LS+   F +   +G   P DG+      P+  T++PE     +T+
Sbjct: 455 SEDSLTTAAAATEVSLST---FEDEEASGV--PTDGL-----APLTATMAPERA---VTS 501

Query: 445 LPG--------TLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLD 496
            PG        T   PL   G + + SP      P   P PLP    E  +T    E + 
Sbjct: 502 GPGDEEDLAAATTEEPLITAGGEESGSPP-----PDGPPLPLPTVAPERWITPAQREHVG 556

Query: 497 QGELEQLNAELGLEPETPPKPPD-APPLGP 525
                    E G   E  P PP+ + P+GP
Sbjct: 557 MKGQAGPKGEKGDAGEELPGPPEPSGPVGP 586


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 68/279 (24%), Positives = 102/279 (36%), Gaps = 31/279 (11%)

Query: 269 PPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFSVSRA 328
           PP    P  +T    +   +  SP +    + LAL+   +  S    ++  +  F     
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434

Query: 329 TTPQLTDVSEDLDQQSLPSEP--EETLSRDLGEGEEGELAPPEDLLGRPQALSR-QALDS 385
              Q +  S      + P  P  +  LS       +  L+P    L  P  +   QAL S
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494

Query: 386 EEEEEDVAAKETLLRLSSPLHFVNTHFNGA-GSPPDGVKCSPGGPVETLSP---ETVSGG 441
                  A   +L+    PL   ++    +  +PP  +   P   + +L+P   +T S  
Sbjct: 495 LASHSPQAPLSSLIM--PPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAP 552

Query: 442 LTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQP-------LPAPEEEEALTTEDFEL 494
           LT  P   +PP       PAP P   PP P  +P P        P P+   AL +   + 
Sbjct: 553 LTT-PHLETPPC------PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG 605

Query: 495 LDQGELEQLNAE-------LGLEP-ETPPKPPDAPPLGP 525
           L    L  L          L L P + PP PP +PPL P
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP 644



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 54/199 (27%), Positives = 69/199 (34%), Gaps = 38/199 (19%)

Query: 343 QSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSEEEEEDVAAKETLLRLS 402
           Q LPS P   L+            PP      PQA    AL   +      A   L  L+
Sbjct: 604 QGLPSPPLSPLA-----------TPP------PQAPPXLALPPLQAPPSPPASPPLSPLA 646

Query: 403 SP---------LHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPL 453
           +P         +H +   F+   SPP     SP  P       + +    A P   +PPL
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP--PASPPVSPSATPPSQAPPSLAAPPL 704

Query: 454 CLVGSDPAP---SPSILPPVPQDSPQ----PLPAPEEEEALTTEDFELLDQGELEQLNAE 506
            +  S PA    SPS  PP PQ  P     PL  P    A             +  L A 
Sbjct: 705 QVPPSPPASPPMSPSATPP-PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763

Query: 507 LGLEPETPPKPPDAPPLGP 525
             L+   PP PP + P+ P
Sbjct: 764 PPLQ--VPPSPPASLPMSP 780



 Score = 29.6 bits (65), Expect = 7.4
 Identities = 22/66 (33%), Positives = 26/66 (39%), Gaps = 4/66 (6%)

Query: 417 SPPDGVKCSP-GGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSP 475
           SPP  +  SP   P     P   +  L ALP   SPP    G  P    + LP  P  +P
Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATP 827

Query: 476 QPLPAP 481
            P   P
Sbjct: 828 PPQAPP 833


>gi|92091600 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain
           1 isoform c [Homo sapiens]
          Length = 1450

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 39/126 (30%), Positives = 47/126 (37%), Gaps = 29/126 (23%)

Query: 426 PGGPVETLSPETVSGGLTALPG-----TLSPPLCLVG-SDPAPSPSI------------- 466
           P  P E L   T   GL A P      +  PP C    S  AP P +             
Sbjct: 95  PATPPEPLPTTTEDEGLPAAPPIPPRRSCLPPTCFTTPSTAAPDPVLPPLPAKRHLAELS 154

Query: 467 LPPVPQDSPQP-----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAP 521
           +PPVP  +  P     LP  EEE  L +     L      Q    L   P+ PP+PP  P
Sbjct: 155 VPPVPPRTGPPRLLVSLPTKEEESLLPS-----LSSPPQPQSEEPLSTLPQGPPQPPSPP 209

Query: 522 PLGPDI 527
           P  P+I
Sbjct: 210 PCPPEI 215


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 63/222 (28%), Positives = 79/222 (35%), Gaps = 40/222 (18%)

Query: 346  PSEPEETLSRDLGEGEEGELAPPEDL-LGRPQALSRQALDSE------------EEEEDV 392
            P+ P    S   G G   E A  E L LG P    R  LD E             +EED 
Sbjct: 1330 PAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKR--LDEELKRNLETLPSFSSDEEDS 1387

Query: 393  AAKETLLRLSSPLHFVNTHFNGAGSPP-DGVK--CSPGGPVETLSPETVSGGLTALPG-- 447
             AK   L+ S     +++  +    PP  G K   +P GP   L+P     G   LPG  
Sbjct: 1388 VAKNRDLQES-----ISSAISALDDPPLAGPKDTSTPDGP--PLAPAAAVPGPPPLPGLP 1440

Query: 448  ------TLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELE 501
                  T  PPL  +   P P+P   PP P   PQP P P   +        L+      
Sbjct: 1441 SANSNGTPEPPL--LEEKPPPTP---PPAPTPQPQPPPPPPPPQPALPSPPPLV--APTP 1493

Query: 502  QLNAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAVAEP 543
                   L P  PP  P  PP  P   + + +  E  A   P
Sbjct: 1494 SSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 32/90 (35%), Positives = 38/90 (42%), Gaps = 13/90 (14%)

Query: 414  GAGSPPDGVKCSPGGP-----VETLSPETVSGGLTA-----LPGTLSP-PLCLVGSDPAP 462
            GAG PP      P GP          PET   GL       LP T++  PL L+ S P  
Sbjct: 977  GAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQ 1036

Query: 463  SPSILPPVPQDSPQPLPAPEEEEALTTEDF 492
            +    PP P   P P PA E +  LT+  F
Sbjct: 1037 AAP--PPPPPPPPPPAPASEPKGGLTSPIF 1064



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 67/280 (23%), Positives = 92/280 (32%), Gaps = 43/280 (15%)

Query: 268 APPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSE-LSDEEASILESGGFSVS 326
           A PGG  P AE   + E  +          +T+ A  +   +  +D    +  SGG    
Sbjct: 626 AGPGG--PPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGP 683

Query: 327 RATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALDSE 386
             T  +L    ED  +  L S    + S D     EG  A  E  LGR +   +      
Sbjct: 684 PGTPYELA--KEDPQRYHLQSVIRTSASLD-----EGATAALELGLGRLKEKKKGPERGG 736

Query: 387 EEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGV---KCSPGGPVETLSPETVSGGLT 443
           E  E +A        +S +H+      GAG+   G    K  P  P    S +    GL 
Sbjct: 737 ETPEGLA--------TSVVHY------GAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLL 782

Query: 444 ALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQL 503
              G    PL L    P   PS+L   P  SP             T D            
Sbjct: 783 LEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRD------------ 830

Query: 504 NAELGLEPETPPKPPDAPPLGPDIHSLVQSDQEAQAVAEP 543
               G     PP PP  PP+   + + ++S     A   P
Sbjct: 831 ----GAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSP 866



 Score = 33.1 bits (74), Expect = 0.67
 Identities = 31/98 (31%), Positives = 38/98 (38%), Gaps = 14/98 (14%)

Query: 413  NGAGSPPDGVKCSPGGP--VETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPP- 469
            NG   PP   +  P  P    T  P+         P   SPP  +  +  +P P  LPP 
Sbjct: 1445 NGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPP 1504

Query: 470  ----VPQDSPQPLPA-------PEEEEALTTEDFELLD 496
                +P   P P PA       PEE  A + ED EL D
Sbjct: 1505 PPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPD 1542


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 25/132 (18%)

Query: 401 LSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLC----LV 456
           L S  H        +GSPP      P  P++   P T SG L+++PG  +PP      +V
Sbjct: 433 LGSDAHLPPPPTLSSGSPPQ-----PRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVV 487

Query: 457 GSDPAPSPS-----------ILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNA 505
            S    SPS            LPP+      P P+PE+  AL+   F     G L  L  
Sbjct: 488 PSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF----PGMLGALPL 543

Query: 506 ELGLEPETPPKP 517
            L L  + PP P
Sbjct: 544 PLSL-GQPPPSP 554



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 44/156 (28%), Positives = 63/156 (40%), Gaps = 27/156 (17%)

Query: 392 VAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCS---PGGPVETLSPETVSGGLTAL--- 445
           ++A  TL+ L+S L    T    +G+PP     S   PG P  +++  T   G ++L   
Sbjct: 667 LSAPPTLIALNSAL-LAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKA 725

Query: 446 -------PGTLSPPL--CLVG------SDPAPSPSILPPVPQDSPQPLPAPEEEEALTTE 490
                  P  LSP L   L+G      S P   PS+L P     P PL + +    L   
Sbjct: 726 PSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSLLQP-----PGPLLSGQLGLQLLPG 780

Query: 491 DFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPD 526
                   E     A L    + PP+ P+AP L P+
Sbjct: 781 GGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPE 816



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 33/106 (31%), Positives = 41/106 (38%), Gaps = 13/106 (12%)

Query: 427 GGPVETLSPE--TVSGGLTAL--PGTLSPPLCLVGSDPAPS-----PSILPPVPQDSPQP 477
           GGP  +L PE  +VS     L  PG L PP     +DP PS     P  LP     SP P
Sbjct: 159 GGP-GSLPPEPPSVSQAFPTLAGPGGLFPPRL---ADPVPSGGSSSPRFLPRGNAPSPAP 214

Query: 478 LPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPL 523
            P P       + ++    +  L   +      P     PP  PPL
Sbjct: 215 PPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPL 260



 Score = 30.0 bits (66), Expect = 5.6
 Identities = 23/67 (34%), Positives = 26/67 (38%), Gaps = 11/67 (16%)

Query: 414 GAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCLVGSDPAPSPSILPPVPQD 473
           G   PP+ +   PGGP   L+P    G           P  LV S   P PS L P P  
Sbjct: 568 GGQPPPEPLLPPPGGPGPPLAPGEPEG-----------PSLLVASLLPPPPSDLLPPPSA 616

Query: 474 SPQPLPA 480
            P  L A
Sbjct: 617 PPSNLLA 623


>gi|223633941 hypothetical protein LOC389730 [Homo sapiens]
          Length = 1343

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)

Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
           +   L S+ +  L   L +G+ G+L+ P+     P  +  +A D     S E  ED A  
Sbjct: 93  ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147

Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
                + SPL           + PD     P     T SP  ++  +++L  +  P   L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191

Query: 456 VGSDPAPSPSILPPVPQDSPQPL----PAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
               P+P P  L P P  +P PL    P P+   A    D  L+     + +   LG  P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSPPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVP 251

Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
           ++     D     P I  L  S+    A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279


>gi|91206406 hypothetical protein LOC642265 [Homo sapiens]
          Length = 1347

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)

Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
           +   L S+ +  L   L +G+ G+L+ P+     P  +  +A D     S E  ED A  
Sbjct: 93  ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147

Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
                + SPL           + PD     P     T SP  ++  +++L  +  P   L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191

Query: 456 VGSDPAPSPSILPPVPQDSPQPL----PAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
               P+P P  L P P  +P PL    P P+   A    D  L+     + +   LG  P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSPPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVP 251

Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
           ++     D     P I  L  S+    A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279


>gi|146231958 hypothetical protein LOC647060 [Homo sapiens]
          Length = 1347

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)

Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
           +   L S+ +  L   L +G+ G+L+ P+     P  +  +A D     S E  ED A  
Sbjct: 93  ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147

Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
                + SPL           + PD     P     T SP  ++  +++L  +  P   L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191

Query: 456 VGSDPAPSPSILPPVPQDSPQPL----PAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
               P+P P  L P P  +P PL    P P+   A    D  L+     + +   LG  P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSPPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVP 251

Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
           ++     D     P I  L  S+    A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279


>gi|24308007 ADP-ribosylation factor-like 6 interacting protein
           [Homo sapiens]
          Length = 203

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 42/193 (21%), Positives = 79/193 (40%), Gaps = 16/193 (8%)

Query: 39  AEEEAATAEAVGRLATTLWLRLRGWEAVLAAAQRLLVWEKPLHSLVTAAALNGLFWLLSS 98
           AE +  +   +     +L  +L+GW  V+  A ++L WE+          ++ +F ++  
Sbjct: 2   AEGDNRSTNLLAAETASLEEQLQGWGEVMLMADKVLRWERAWFPPAIMGVVSLVFLII-- 59

Query: 99  SSLRPFFLLSVSLLAYF--LLDLWQPRFLPDVSASSPEEPHSDSEGAGSGARPHLLSVPE 156
             L P  L  VS    F  L D   P   P +  S+               R H     E
Sbjct: 60  YYLDPSVLSGVSCFVMFLCLADYLVPILAPRIFGSNKWTTEQQQ-------RFH-----E 107

Query: 157 LCRYLAESWLTFQIHLQELLQYKRQNPAQFCVRVCSGCAVLAVLGHYVPGIMISYIVLLS 216
           +C  L ++        + L   K + P  + + +    A +A +G  V  ++++Y+++ S
Sbjct: 108 ICSNLVKTRRRAVGWWKRLFTLKEEKPKMYFMTMIVSLAAVAWVGQQVHNLLLTYLIVTS 167

Query: 217 ILLWPLVVYHELI 229
           +LL P +  H +I
Sbjct: 168 LLLLPGLNQHGII 180


>gi|169174618 PREDICTED: family with sequence similarity 75, member
           A4 isoform 2 [Homo sapiens]
          Length = 1272

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)

Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
           +   L S+ +  L   L +G+ G+L+ P+     P  +  +A D     S E  ED A  
Sbjct: 18  ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 72

Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
                + SPL           + PD     P     T SP  ++  +++L  +  P   L
Sbjct: 73  -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 116

Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
               P+P P  L P P  +P P    LP P+   A    D  L+     + +   LG  P
Sbjct: 117 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVP 176

Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
           ++     D     P I  L  S+    A
Sbjct: 177 QSLSPHEDLVASVPAISGLGGSNSHVSA 204


>gi|239743732 PREDICTED: family with sequence similarity 75, member
           A4 isoform 1 [Homo sapiens]
          Length = 1361

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)

Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
           +   L S+ +  L   L +G+ G+L+ P+     P  +  +A D     S E  ED A  
Sbjct: 107 ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 161

Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
                + SPL           + PD     P     T SP  ++  +++L  +  P   L
Sbjct: 162 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 205

Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
               P+P P  L P P  +P P    LP P+   A    D  L+     + +   LG  P
Sbjct: 206 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVP 265

Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
           ++     D     P I  L  S+    A
Sbjct: 266 QSLSPHEDLVASVPAISGLGGSNSHVSA 293


>gi|153791826 hypothetical protein LOC26165 [Homo sapiens]
          Length = 1347

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)

Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
           +   L S+ +  L   L +G+ G+L+ P+     P  +  +A D     S E  ED A  
Sbjct: 93  ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147

Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
                + SPL           + PD     P     T SP  ++  +++L  +  P   L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191

Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
               P+P P  L P P  +P P    LP P+   A    D  L+     + +   LG  P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVP 251

Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
           ++     D     P I  L  S+    A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279


>gi|133892686 hypothetical protein LOC727830 [Homo sapiens]
          Length = 1347

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 50/208 (24%), Positives = 77/208 (37%), Gaps = 30/208 (14%)

Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
           +   L S+ +  L   L +G+ G+L+ P+     P  +  +A D     S E  ED A  
Sbjct: 93  ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAPI 148

Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
            +LL                 + PD     P     T SP  ++  +++L  +  P   L
Sbjct: 149 LSLL-----------------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191

Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
               P+P P  L P P  +P P    LP P+   A    D  L+     + +   LG  P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVALPLGTVP 251

Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
           ++     D     P I  L  S+    A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279


>gi|165377334 hypothetical protein LOC727905 [Homo sapiens]
          Length = 1347

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 51/208 (24%), Positives = 78/208 (37%), Gaps = 30/208 (14%)

Query: 341 DQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSRQALD-----SEEEEEDVAAK 395
           +   L S+ +  L   L +G+ G+L+ P+     P  +  +A D     S E  ED A  
Sbjct: 93  ETSDLLSQLQSLLGPHLDKGDFGQLSGPDP----PGEVGERAPDGASQSSHEPMEDAAP- 147

Query: 396 ETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTALPGTLSPPLCL 455
                + SPL           + PD     P     T SP  ++  +++L  +  P   L
Sbjct: 148 -----ILSPL-----------ASPDPQAKHPQDLASTPSPGPMTTSVSSLSASQPPEPSL 191

Query: 456 VGSDPAPSPSILPPVPQDSPQP----LPAPEEEEALTTEDFELLDQGELEQLNAELGLEP 511
               P+P P  L P P  +P P    LP P+   A    D  L+     + +   LG  P
Sbjct: 192 PLEHPSPEPPALFPHPPHTPDPLACSLPPPKGFTAPPLRDSTLITPSHCDSVAFPLGTVP 251

Query: 512 ETPPKPPDAPPLGPDIHSLVQSDQEAQA 539
           ++     D     P I  L  S+    A
Sbjct: 252 QSLSPHEDLVASVPAISGLGGSNSHVSA 279


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 59/248 (23%), Positives = 82/248 (33%), Gaps = 45/248 (18%)

Query: 309 ELSDEEASILESGGFSVSRATTPQLTDVSEDLDQQSLPSEPEETLSRDLGEGEE--GELA 366
           EL ++ A + E     +  A    +  ++E   Q S   +  ETL     E         
Sbjct: 403 ELQEQVALLTER----LRDAENESMAKIAELEKQLSQARKELETLRERFSESTAMGASRR 458

Query: 367 PPEDLLGRPQALSR-QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCS 425
           PPE     P A +R  AL+ + EE +      +LR       +        +P  G   +
Sbjct: 459 PPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPT 518

Query: 426 PGGPVETLSPETVSGGLTA----------LPGTLSPPLCLVGSDP-------APSPSILP 468
           PG P  + SP+       A          LPG  SP      + P       +P P   P
Sbjct: 519 PGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAP 578

Query: 469 PVPQDSPQPLPAPEEEEALTTEDFELLDQGELEQLNAELGLEPETPPKPPDAPPLGPDIH 528
           P+P D P P P P                             P  PP PP  PP G    
Sbjct: 579 PLPGDLPPPPPPPPPPPGTD---------------------GPVPPPPPPPPPPPGGPPD 617

Query: 529 SLVQSDQE 536
           +L + D E
Sbjct: 618 ALGRRDSE 625


>gi|83367077 mucin 16 [Homo sapiens]
          Length = 14507

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 62/257 (24%), Positives = 89/257 (34%), Gaps = 25/257 (9%)

Query: 265  GKNAPPGGDEPLAETESESEAELAGFSPVVDVKKTALALAITDSELSDEEASILESGGFS 324
            G   P G    L  T + S+      S +    K +L   + ++ +S+E +S  E     
Sbjct: 9255 GITYPTGDTNVLTSTPAFSDT-----SRIQTKSKLSLTPGLMETSISEETSSATEKSTV- 9308

Query: 325  VSRATTPQLTDVSE----DLDQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQALSR 380
            +S   T   T+VS        + S+P   + T+S D        ++ P   L R ++   
Sbjct: 9309 LSSVPTGATTEVSRTEAISSSRTSIPGPAQSTMSSDTSMETITRISTP---LTRKESTDM 9365

Query: 381  QALDSEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSG 440
                        +     L  SS   +  TH       P  V  +P     +  PE VS 
Sbjct: 9366 AITPKTGPSGATSQGTFTLDSSSTASWPGTHSATTQRFPQSVVTTP----MSRGPEDVSW 9421

Query: 441  GLTALPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLPAPEEEEALTTEDFELLDQGEL 500
                     SPP  LV S    SPS L   P  S    P P       T  F  +     
Sbjct: 9422 PSPLSVEKNSPPSSLVSSSSVTSPSPLYSTPSGSSHSSPVP------VTSLFTSIMMKAT 9475

Query: 501  EQLNAELGLEPETPPKP 517
            + L+A   LEPET   P
Sbjct: 9476 DMLDA--SLEPETTSAP 9490



 Score = 30.4 bits (67), Expect = 4.3
 Identities = 47/215 (21%), Positives = 76/215 (35%), Gaps = 19/215 (8%)

Query: 275  PLAETESESEAELAGFSP-----VVDVKKTALALAITDSELSDEEASILESGGFSVSRAT 329
            P+A T +     ++  +P     ++    ++L   + +   S E +S  E    S+S   
Sbjct: 8675 PMATTSTLGNTSVSTSTPAFPETMMTQPTSSLTSGLREISTSQETSSATERSA-SLSGMP 8733

Query: 330  TPQLTDVSE----DLDQQSLPSEPEETLSRDLGEGEEGELAPPEDLLGRPQ-ALSRQALD 384
            T   T VS      L + S P   + T+S ++       ++ P    G  +  ++ +   
Sbjct: 8734 TGATTKVSRTEALSLGRTSTPGPAQSTISPEISTETITRISTPLTTTGSAEMTITPKTGH 8793

Query: 385  SEEEEEDVAAKETLLRLSSPLHFVNTHFNGAGSPPDGVKCSPGGPVETLSPETVSGGLTA 444
            S    +     +T  R S P     TH       P     +P     +  PE VS     
Sbjct: 8794 SGASSQGTFTLDTSSRASWP----GTHSAATHRSPHSGMTTP----MSRGPEDVSWPSRP 8845

Query: 445  LPGTLSPPLCLVGSDPAPSPSILPPVPQDSPQPLP 479
                 SPP  LV      SPS L   P +S    P
Sbjct: 8846 SVEKTSPPSSLVSLSAVTSPSPLYSTPSESSHSSP 8880


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.132    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,808,009
Number of Sequences: 37866
Number of extensions: 1498974
Number of successful extensions: 15047
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 610
Number of HSP's that attempted gapping in prelim test: 10821
Number of HSP's gapped (non-prelim): 3719
length of query: 543
length of database: 18,247,518
effective HSP length: 107
effective length of query: 436
effective length of database: 14,195,856
effective search space: 6189393216
effective search space used: 6189393216
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.