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Search of human proteins with 187173288
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|187173288 troponin T1, skeletal, slow isoform a [Homo
sapiens]
(278 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens] 557 e-159
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 511 e-145
gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] 480 e-136
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 315 3e-86
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 313 1e-85
gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] 312 2e-85
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 311 5e-85
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 308 3e-84
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 308 4e-84
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 307 6e-84
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 304 6e-83
gi|92859701 myosin VI [Homo sapiens] 65 5e-11
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 64 2e-10
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 64 2e-10
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 62 4e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 62 6e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 7e-10
gi|148746195 trichohyalin [Homo sapiens] 60 2e-09
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 60 3e-09
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 60 3e-09
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 60 3e-09
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 60 3e-09
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 59 5e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 57 1e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 57 2e-08
gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 57 2e-08
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 57 2e-08
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 57 2e-08
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 56 3e-08
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 55 9e-08
>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
Length = 278
Score = 557 bits (1435), Expect = e-159
Identities = 278/278 (100%), Positives = 278/278 (100%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK
Sbjct: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
Query: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE
Sbjct: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL
Sbjct: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 278
MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK
Sbjct: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 278
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 511 bits (1317), Expect = e-145
Identities = 262/278 (94%), Positives = 262/278 (94%), Gaps = 16/278 (5%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK
Sbjct: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
Query: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE
Sbjct: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
MKVRILSERKKPLDIDYMGEEQL REKAQELSDWIHQLESEKFDL
Sbjct: 181 MKVRILSERKKPLDIDYMGEEQL----------------REKAQELSDWIHQLESEKFDL 224
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 278
MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK
Sbjct: 225 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 262
>gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens]
Length = 251
Score = 480 bits (1235), Expect = e-136
Identities = 251/278 (90%), Positives = 251/278 (90%), Gaps = 27/278 (9%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
MSDTEEQEYEEEQPEEEAAEEEEE EEERPKPSRPVVPPLIPPKIPEGER
Sbjct: 1 MSDTEEQEYEEEQPEEEAAEEEEE-----------EEERPKPSRPVVPPLIPPKIPEGER 49
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK
Sbjct: 50 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 109
Query: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE
Sbjct: 110 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 169
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
MKVRILSERKKPLDIDYMGEEQL REKAQELSDWIHQLESEKFDL
Sbjct: 170 MKVRILSERKKPLDIDYMGEEQL----------------REKAQELSDWIHQLESEKFDL 213
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 278
MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK
Sbjct: 214 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 251
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 315 bits (807), Expect = 3e-86
Identities = 168/281 (59%), Positives = 208/281 (74%), Gaps = 26/281 (9%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
MSD E ++ EE+ EEE A+EEEE E+ + EEE+P+P L PKIPEGE+
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEDTAE-EDAEEEKPRPK------LTAPKIPEGEK 53
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 54 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 113
Query: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 114 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 173
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
MK +IL+ER+KPL+ID++GE++L R+KA+EL + +HQLE +KF+
Sbjct: 174 MKKKILAERRKPLNIDHLGEDKL----------------RDKAKELWETLHQLEIDKFEF 217
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAG---KGRVGGRWK 278
KLK+QKY+I L +RI AQK K AG KG+VGGRWK
Sbjct: 218 GEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 258
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 313 bits (802), Expect = 1e-85
Identities = 178/303 (58%), Positives = 211/303 (69%), Gaps = 43/303 (14%)
Query: 1 MSDTEE--QEYEEEQPEEEAAEEEEEAPEEP-EPVAEPEEER------------------ 39
MSD EE +EYEEE+ EE A EE+EEA EE E AE EE R
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM 60
Query: 40 ----PKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEE 95
PKP R +P L+PPKIP+GERVDFDDIHRKRMEKDL ELQ LI+ HFE RKKEEEE
Sbjct: 61 EESKPKP-RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEE 119
Query: 96 LVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLS 155
LV+LK+RIERRR+ERAEQQR R E+E+ERQ +LAEE+ R+EEEE +++AED+A+KKK LS
Sbjct: 120 LVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALS 179
Query: 156 NMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQP 215
NM HFGGY+ K E+K GKRQT RE K +IL+ER+K L ID++ E+QL
Sbjct: 180 NM-MHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQL------------ 226
Query: 216 SCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGG 275
REKA+EL I+ LE+EKFDL K KQQKYEINVL NRI+ QK K GK +V G
Sbjct: 227 ----REKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTG 282
Query: 276 RWK 278
RWK
Sbjct: 283 RWK 285
>gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]
Length = 256
Score = 312 bits (799), Expect = 2e-85
Identities = 170/281 (60%), Positives = 208/281 (74%), Gaps = 28/281 (9%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
MSD E ++ EE+ EEE E +EEA E E V EPEE +P+P L PKIPEGE+
Sbjct: 1 MSDEEVEQVEEQYEEEE--EAQEEAAEVHEEVHEPEE-KPRPK------LTAPKIPEGEK 51
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 52 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 111
Query: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 112 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 171
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
MK +IL+ER+KPL+ID++GE++L R+KA+EL + +HQLE +KF+
Sbjct: 172 MKKKILAERRKPLNIDHLGEDKL----------------RDKAKELWETLHQLEIDKFEF 215
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAG---KGRVGGRWK 278
KLK+QKY+I L +RI AQK K AG KG+VGGRWK
Sbjct: 216 GEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 256
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 311 bits (796), Expect = 5e-85
Identities = 168/281 (59%), Positives = 205/281 (72%), Gaps = 34/281 (12%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
MSD E ++ EE+ EEE A+EEEE EE +P RPK L PKIPEGE+
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKP-------RPK--------LTAPKIPEGEK 45
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 46 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 105
Query: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 106 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 165
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
MK +IL+ER+KPL+ID++GE++L R+KA+EL + +HQLE +KF+
Sbjct: 166 MKKKILAERRKPLNIDHLGEDKL----------------RDKAKELWETLHQLEIDKFEF 209
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAG---KGRVGGRWK 278
KLK+QKY+I L +RI AQK K AG KG+VGGRWK
Sbjct: 210 GEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 250
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 308 bits (789), Expect = 3e-84
Identities = 177/313 (56%), Positives = 211/313 (67%), Gaps = 53/313 (16%)
Query: 1 MSDTEE--QEYEEEQPEEEAAEEEEE-----------APEEPEPVAEPEEER-------- 39
MSD EE +EYEEE+ EE A EEEE+ A E+ E AE EE R
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
Query: 40 --------------PKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVH 85
PKP R +P L+PPKIP+GERVDFDDIHRKRMEKDL ELQ LI+ H
Sbjct: 61 EAKEAEDGPMEESKPKP-RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAH 119
Query: 86 FEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAE 145
FE RKKEEEELV+LK+RIERRR+ERAEQQR R E+E+ERQ +LAEE+ R+EEEE +++AE
Sbjct: 120 FENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAE 179
Query: 146 DDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRA 205
D+A+KKK LSNM HFGGY+ K E+K GKRQT RE K +IL+ER+K L ID++ E+QL
Sbjct: 180 DEARKKKALSNM-MHFGGYIQKTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQL-- 236
Query: 206 RSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFR 265
REKA+EL I+ LE+EKFDL K KQQKYEINVL NRI+ QK
Sbjct: 237 --------------REKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVS 282
Query: 266 KGAGKGRVGGRWK 278
K GK +V GRWK
Sbjct: 283 KTRGKAKVTGRWK 295
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 308 bits (788), Expect = 4e-84
Identities = 178/306 (58%), Positives = 211/306 (68%), Gaps = 46/306 (15%)
Query: 1 MSDTEE--QEYEEEQPEEEAAEEEEEAPEEP-EPVAEPEEER------------------ 39
MSD EE +EYEEE+ EE A EE+EEA EE E AE EE R
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM 60
Query: 40 ----PKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEE 95
PKP R +P L+PPKIP+GERVDFDDIHRKRMEKDL ELQ LI+ HFE RKKEEEE
Sbjct: 61 EESKPKP-RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEE 119
Query: 96 LVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLS 155
LV+LK+RIERRR+ERAEQQR R E+E+ERQ +LAEE+ R+EEEE +++AED+A+KKK LS
Sbjct: 120 LVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALS 179
Query: 156 NMGAHFGGYLVK---AEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPP 212
NM HFGGY+ K E+K GKRQT RE K +IL+ER+K L ID++ E+QL
Sbjct: 180 NM-MHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQL--------- 229
Query: 213 SQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGR 272
REKA+EL I+ LE+EKFDL K KQQKYEINVL NRI+ QK K GK +
Sbjct: 230 -------REKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAK 282
Query: 273 VGGRWK 278
V GRWK
Sbjct: 283 VTGRWK 288
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 307 bits (787), Expect = 6e-84
Identities = 176/300 (58%), Positives = 211/300 (70%), Gaps = 40/300 (13%)
Query: 1 MSDTEE--QEYEEEQPEE--EAAEEEEEAPEEPEPVAEPEEE----------------RP 40
MSD EE +EYEEE+ EE EAAEE+ EA E E E+E +P
Sbjct: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
Query: 41 KPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALK 100
KP R +P L+PPKIP+GERVDFDDIHRKRMEKDL ELQ LI+ HFE RKKEEEELV+LK
Sbjct: 61 KP-RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLK 119
Query: 101 ERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAH 160
+RIERRR+ERAEQQR R E+E+ERQ +LAEE+ R+EEEE +++AED+A+KKK LSNM H
Sbjct: 120 DRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MH 178
Query: 161 FGGYLVKA--EQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCP 218
FGGY+ KA E+K GKRQT RE K +IL+ER+K L ID++ E+QL
Sbjct: 179 FGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQL--------------- 223
Query: 219 AREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 278
REKA+EL I+ LE+EKFDL K KQQKYEINVL NRI+ QK K GK +V GRWK
Sbjct: 224 -REKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 282
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 304 bits (778), Expect = 6e-83
Identities = 165/281 (58%), Positives = 203/281 (72%), Gaps = 34/281 (12%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
MSD E ++ EE+ EEE A+EEEE EE +P RPK L PKIPEGE+
Sbjct: 1 MSDEEVEQVEEQYEEEEEAQEEEEVQEEEKP-------RPK--------LTAPKIPEGEK 45
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
VDFDDI +KR KDL+ELQ LID HFE RKKEEEELVALKERIE+RR+ERAEQQR R EK
Sbjct: 46 VDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEK 105
Query: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
ERERQ +LAEEK R+EEE+AK+RAEDD KKKK LS+MGA++ YL KA+QKRGK+QT RE
Sbjct: 106 ERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKADQKRGKKQTARE 165
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
MK +IL+ER+KPL+ID++GE++L R+KA+EL + +HQLE +KF+
Sbjct: 166 MKKKILAERRKPLNIDHLGEDKL----------------RDKAKELWETLHQLEIDKFEF 209
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAG---KGRVGGRWK 278
KLK+QKY+I + R+ KF K AG KG+VGGRWK
Sbjct: 210 GEKLKRQKYDIMNVRARVQMLAKFSKKAGTPAKGKVGGRWK 250
>gi|92859701 myosin VI [Homo sapiens]
Length = 1285
Score = 65.5 bits (158), Expect = 5e-11
Identities = 40/144 (27%), Positives = 75/144 (52%), Gaps = 5/144 (3%)
Query: 87 EQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAED 146
+Q+++E E L ++E +E+ R R E ++ R ++E ER+ KL E RK+EEE +K+ ED
Sbjct: 917 KQQEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEMEAKRKQEEEERKKRED 976
Query: 147 DAKKKKVLSNMGAHFGGYLVKAEQKRG---KRQTGREMKVRILSERKKPLDIDYMGEEQL 203
D +K++ + + A + Q++ + + RE+ +RI + + + + L
Sbjct: 977 D--EKRIQAEVEAQLARQKEEESQQQAVLEQERRDRELALRIAQSEAELISDEAQADLAL 1034
Query: 204 RARSAWLPPSQPSCPAREKAQELS 227
R P P A+E ++ LS
Sbjct: 1035 RRNDGTRPKMTPEQMAKEMSEFLS 1058
Score = 34.7 bits (78), Expect = 0.094
Identities = 37/153 (24%), Positives = 66/153 (43%), Gaps = 26/153 (16%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
+E+E E + +E E+E + EE E EEE + + E +R +
Sbjct: 919 QEEEAERLRRIQEEMEKERKRREEDEKRRRKEEEERRMKLEM----------EAKRKQEE 968
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERR------RSERAEQQRFRT 118
+ RK+ E D +Q ++ ++K+EE + A+ E+ ERR R ++E +
Sbjct: 969 E-ERKKREDDEKRIQAEVEAQLARQKEEESQQQAVLEQ-ERRDRELALRIAQSEAELISD 1026
Query: 119 EKERE--------RQAKLAEEKMRKEEEEAKKR 143
E + + + K+ E+M KE E R
Sbjct: 1027 EAQADLALRRNDGTRPKMTPEQMAKEMSEFLSR 1059
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 63.5 bits (153), Expect = 2e-10
Identities = 64/231 (27%), Positives = 103/231 (44%), Gaps = 47/231 (20%)
Query: 22 EEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTL 81
++ PEEP V E E+++ + PV F+D R+ E+ LEL+
Sbjct: 326 DQRLPEEP--VLEDEQQQLEKKLPVT---------------FEDKKRENFERGNLELEKR 368
Query: 82 IDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK-ERERQAKLAEEKMRKEEEEA 140
EQ++KE+E L L ER E+ R ER Q++ R + E E+Q + E R+ EEE
Sbjct: 369 RQALLEQQRKEQERLAQL-ERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEER 427
Query: 141 KKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGE 200
+K E K+ L + E +R +RQ +L++R K + +
Sbjct: 428 RKEIERREAAKRELERQR--------QLEWERNRRQ-------ELLNQRNKEQEDIVV-- 470
Query: 201 EQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEI 251
L+A+ L + + L+D HQLE + D+ +L Q+ EI
Sbjct: 471 --LKAKKKTL---------EFELEALNDKKHQLEGKLQDIRCRLTTQRQEI 510
Score = 46.2 bits (108), Expect = 3e-05
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 9/102 (8%)
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVAL---KERIERRRSERAEQ--QRFRTE 119
+IH K+ L+ Q ++ ++K++E +++ L KE +RR ER +Q + + E
Sbjct: 612 EIHNKQQ----LQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQE 667
Query: 120 KERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHF 161
E +R KL EE+ K EE KK+ ++ K++ +G F
Sbjct: 668 DEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLF 709
Score = 32.3 bits (72), Expect = 0.47
Identities = 54/261 (20%), Positives = 115/261 (44%), Gaps = 38/261 (14%)
Query: 2 SDTEEQEYE-EEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
++ E +E E +EQ + E E++ ++ E + EEER K +I E
Sbjct: 389 AEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRK------------EIERREA 436
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
+ ++++E + Q L++ QR KE+E++V LK ++++ E + +K
Sbjct: 437 AKRELERQRQLEWERNRRQELLN----QRNKEQEDIVVLK---AKKKTLEFELEAL-NDK 488
Query: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
+ + + KL + + R + ++ E K +++ H L +++Q G+ ++
Sbjct: 489 KHQLEGKLQDIRCRLTTQ--RQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQ 546
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKA-QELSDWIHQLESE--- 236
IL+++ K + + + + L L A+E A Q L D + ++E E
Sbjct: 547 ----ILNDQLKQVQQNSLHRDSLVTLKRAL-------EAKELARQHLRDQLDEVEKETRS 595
Query: 237 KFDLMAKLKQQKYEINVLYNR 257
K + Q E+ ++N+
Sbjct: 596 KLQEIDIFNNQLKELREIHNK 616
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 63.5 bits (153), Expect = 2e-10
Identities = 64/231 (27%), Positives = 103/231 (44%), Gaps = 47/231 (20%)
Query: 22 EEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTL 81
++ PEEP V E E+++ + PV F+D R+ E+ LEL+
Sbjct: 326 DQRLPEEP--VLEDEQQQLEKKLPVT---------------FEDKKRENFERGNLELEKR 368
Query: 82 IDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK-ERERQAKLAEEKMRKEEEEA 140
EQ++KE+E L L ER E+ R ER Q++ R + E E+Q + E R+ EEE
Sbjct: 369 RQALLEQQRKEQERLAQL-ERAEQERKERERQEQERKRQLELEKQLEKQRELERQREEER 427
Query: 141 KKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGE 200
+K E K+ L + E +R +RQ +L++R K + +
Sbjct: 428 RKEIERREAAKRELERQR--------QLEWERNRRQ-------ELLNQRNKEQEDIVV-- 470
Query: 201 EQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEI 251
L+A+ L + + L+D HQLE + D+ +L Q+ EI
Sbjct: 471 --LKAKKKTL---------EFELEALNDKKHQLEGKLQDIRCRLTTQRQEI 510
Score = 46.2 bits (108), Expect = 3e-05
Identities = 30/102 (29%), Positives = 54/102 (52%), Gaps = 9/102 (8%)
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVAL---KERIERRRSERAEQ--QRFRTE 119
+IH K+ L+ Q ++ ++K++E +++ L KE +RR ER +Q + + E
Sbjct: 612 EIHNKQQ----LQKQKSMEAERLKQKEQERKIIELEKQKEEAQRRAQERDKQWLEHVQQE 667
Query: 120 KERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHF 161
E +R KL EE+ K EE KK+ ++ K++ +G F
Sbjct: 668 DEHQRPRKLHEEEKLKREESVKKKDGEEKGKQEAQDKLGRLF 709
Score = 32.3 bits (72), Expect = 0.47
Identities = 54/261 (20%), Positives = 115/261 (44%), Gaps = 38/261 (14%)
Query: 2 SDTEEQEYE-EEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
++ E +E E +EQ + E E++ ++ E + EEER K +I E
Sbjct: 389 AEQERKERERQEQERKRQLELEKQLEKQRELERQREEERRK------------EIERREA 436
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEK 120
+ ++++E + Q L++ QR KE+E++V LK ++++ E + +K
Sbjct: 437 AKRELERQRQLEWERNRRQELLN----QRNKEQEDIVVLK---AKKKTLEFELEAL-NDK 488
Query: 121 ERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
+ + + KL + + R + ++ E K +++ H L +++Q G+ ++
Sbjct: 489 KHQLEGKLQDIRCRLTTQ--RQEIESTNKSRELRIAEITHLQQQLQESQQMLGRLIPEKQ 546
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKA-QELSDWIHQLESE--- 236
IL+++ K + + + + L L A+E A Q L D + ++E E
Sbjct: 547 ----ILNDQLKQVQQNSLHRDSLVTLKRAL-------EAKELARQHLRDQLDEVEKETRS 595
Query: 237 KFDLMAKLKQQKYEINVLYNR 257
K + Q E+ ++N+
Sbjct: 596 KLQEIDIFNNQLKELREIHNK 616
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 62.4 bits (150), Expect = 4e-10
Identities = 48/203 (23%), Positives = 99/203 (48%), Gaps = 16/203 (7%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
++QE + ++ EE+ ++EE+ E+ E + E EE+ K + E++
Sbjct: 244 QKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE--EQTGEQEEQMREQ 301
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE--- 121
+ + E+ + E + + EQ K+EE++ KE++ ++ + +Q+ E+E
Sbjct: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM 361
Query: 122 --RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGR 179
+E Q + EE+MRK+EE+ +K+ E K+++ + G EQK R+
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMG------EQKEQMREQEE 415
Query: 180 EMKVRILSERKKPLDIDYMGEEQ 202
+M + RK+ ++MGE++
Sbjct: 416 QMGEQKEQMRKQE---EHMGEQK 435
Score = 58.9 bits (141), Expect = 5e-09
Identities = 35/147 (23%), Positives = 79/147 (53%), Gaps = 11/147 (7%)
Query: 6 EQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDD 65
EQE + + EE+ E+EE+ ++ E + E EE+ K + + E+V +
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE--------QEEQVQKQE 247
Query: 66 IHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQ 125
++ E+ + + + + EQ +++EE+++ KE+ E+ ++++ R E+E Q
Sbjct: 248 EQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMR---EQEEQ 304
Query: 126 AKLAEEKMRKEEEEAKKRAEDDAKKKK 152
+ EE+MR++EE+ +++ E K+++
Sbjct: 305 MREQEEQMREQEEQMREQEEQMGKQEE 331
Score = 53.1 bits (126), Expect = 3e-07
Identities = 47/249 (18%), Positives = 116/249 (46%), Gaps = 29/249 (11%)
Query: 6 EQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDD 65
EQE + + E + E+E + E+ E + E EE+ K + E++ +
Sbjct: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQK---------------QEEQMGEQE 226
Query: 66 IHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQ----RFRTEKE 121
++ E+ + E + + EQ +K+EE++ +E++ + + EQ+ + + + E
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286
Query: 122 RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREM 181
+E Q EE+MR++EE+ +++ E ++++ + G + EQ +++ E
Sbjct: 287 QEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMG---KQEEQMWEQKEQMWEQ 343
Query: 182 KVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLM 241
K ++ + ++ MGE++ + + + R++ +++ Q+ ++ + M
Sbjct: 344 KEQMWKQEEQ------MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQE-EQM 396
Query: 242 AKLKQQKYE 250
+ K+Q E
Sbjct: 397 GEQKEQMGE 405
Score = 52.0 bits (123), Expect = 6e-07
Identities = 38/147 (25%), Positives = 75/147 (51%), Gaps = 6/147 (4%)
Query: 4 TEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDF 63
T EQE + + EE+ E+EE+ E+ E + E EE+ K + + E++
Sbjct: 291 TGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQK-EQMWEQKEQMWK 349
Query: 64 DDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERI---ERRRSERAEQQRFRTEK 120
+ E+ + + + + EQ +K+EE++ +E++ E + E+ EQ + E+
Sbjct: 350 QEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQ 409
Query: 121 ERERQAKLAEEK--MRKEEEEAKKRAE 145
RE++ ++ E+K MRK+EE ++ E
Sbjct: 410 MREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 49.3 bits (116), Expect = 4e-06
Identities = 35/170 (20%), Positives = 86/170 (50%), Gaps = 16/170 (9%)
Query: 1 MSDTEEQ---EYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPE 57
M + EEQ + E+ + EE+ E+EE+ E+ E + E EE+ + + +
Sbjct: 271 MREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE--------Q 322
Query: 58 GERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSE---RAEQQ 114
E++ + ++ + E + + EQ ++EE++ +E++ ++ + + EQ
Sbjct: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQM 382
Query: 115 RFRTEKERERQAKLAEEK--MRKEEEEAKKRAEDDAKKKKVLSNMGAHFG 162
R + E+ R+++ ++ E+K M +++E+ +++ E ++K+ + H G
Sbjct: 383 RKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMG 432
Score = 36.6 bits (83), Expect = 0.025
Identities = 48/268 (17%), Positives = 114/268 (42%), Gaps = 25/268 (9%)
Query: 6 EQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDD 65
EQE + + E + E+E + E+ V E E + + V + EG+ V +
Sbjct: 77 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-VREQE 135
Query: 66 IHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE---- 121
+ E + E + + Q +++E ++ + ++ + + EQ+ E+E
Sbjct: 136 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMG 195
Query: 122 -RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFG------------------ 162
+E Q EE+M ++EE+ +K+ E ++++ + G
Sbjct: 196 EQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEE 255
Query: 163 GYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREK 222
+ EQ R + + RE + ++L ++++ + GE++ + R + RE+
Sbjct: 256 QMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQ 315
Query: 223 AQELSDWIHQLESEKFDLMAKLKQQKYE 250
+++ + Q+ ++ + M + K+Q +E
Sbjct: 316 EEQMREQEEQMGKQE-EQMWEQKEQMWE 342
Score = 35.0 bits (79), Expect = 0.072
Identities = 41/250 (16%), Positives = 114/250 (45%), Gaps = 22/250 (8%)
Query: 6 EQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDD 65
EQE + + E + E+E + E+ V E E + + V + EG+
Sbjct: 56 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV-------REQEGQ------ 102
Query: 66 IHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE---R 122
+ E + E + + Q +++E ++ + ++ + + EQ+ E+E R
Sbjct: 103 --VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 160
Query: 123 ERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMK 182
E++ ++ E++ + E+E + R E + + ++ MG G + + E++ G+++ + +
Sbjct: 161 EQEGQVREQEGQVREQEGQVR-EQEGQVREQEGQMGEQ-EGQMGEQEEQMGEQEEQMQKQ 218
Query: 183 VRILSERKKPL--DIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
+ E+++ + + MGE++ + + + R++ +++ + Q+ ++ +
Sbjct: 219 EEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQM 278
Query: 241 MAKLKQQKYE 250
+ + +Q + E
Sbjct: 279 LKQKEQTEQE 288
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 62.0 bits (149), Expect = 6e-10
Identities = 56/247 (22%), Positives = 114/247 (46%), Gaps = 34/247 (13%)
Query: 7 QEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDI 66
+E EE+ E+E E+EE +E E + E E+ + + ++
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK---------------------- 384
Query: 67 HRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERI---ERRRSERAEQQRFRTEKERE 123
R E+ + E + I E +++EE++ +E++ E E+ E+ R + EK RE
Sbjct: 385 -MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE 443
Query: 124 RQAKL--AEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREM 181
++ K+ EEK+R++EE +++ E +++ + A + E+ R + + RE
Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM---QEQEEKMRRQEEKIREQ 500
Query: 182 KVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLM 241
+ +I + +K + + M +EQ W + C EK QE + + + E + +
Sbjct: 501 EKKIREQEEKIREQEEMMQEQ--EEKMW-EQEEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Query: 242 AKLKQQK 248
+L+QQ+
Sbjct: 558 VRLRQQE 564
Score = 57.0 bits (136), Expect = 2e-08
Identities = 55/254 (21%), Positives = 119/254 (46%), Gaps = 33/254 (12%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
++QE + + EE+ E EE+ E+ E + E EE K+ E + ++
Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEE----------------KMRRQEEMMWE 327
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFR-TEKERE 123
+ R +++++ + E++ +E EE + +E+I + +R E+++ R EK +E
Sbjct: 328 KEEKMRRQEEMMWEK-------EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 380
Query: 124 RQAKL--AEEKMRKEEEEAKKR----AEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQT 177
++AK+ EEK+R++EE+ +++ E + K + M + E+ R + +
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440
Query: 178 GREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEK 237
RE + +I + +K + + M +EQ C K QE + + + E +
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMG---EQEGKMCEQEAKMQEQEEKMRRQEEKI 497
Query: 238 FDLMAKLKQQKYEI 251
+ K+++Q+ +I
Sbjct: 498 REQEKKIREQEEKI 511
Score = 51.6 bits (122), Expect = 7e-07
Identities = 45/199 (22%), Positives = 97/199 (48%), Gaps = 23/199 (11%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
+EQE + + EE+ E+EE+ E+ E + E EE+ + + + E +
Sbjct: 379 QEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKM--------WEQEEEMQEQ 430
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERI----------ERRRSERAEQQ 114
+ +R E+ + E + I E+ +++EE + +E++ E + E+ E+
Sbjct: 431 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM 490
Query: 115 RFRTEKERERQAKL--AEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKR 172
R + EK RE++ K+ EEK+R++EE +++ E ++++ + + E+ R
Sbjct: 491 RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM---QEQEEKMR 547
Query: 173 GKRQTGREMKVRILSERKK 191
+ + RE +VR+ + +K
Sbjct: 548 RQEEKMREQEVRLRQQEEK 566
Score = 47.4 bits (111), Expect = 1e-05
Identities = 34/143 (23%), Positives = 75/143 (52%), Gaps = 6/143 (4%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGE-RV 61
+ +EQE + + EE+ E+E++ E+ E + E EE + + K+ E E ++
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ--EGKMCEQEAKM 483
Query: 62 DFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERI---ERRRSERAEQQRFRT 118
+ +R E+ + E + I E+ +++EE + +E++ E + E+ E+ + +
Sbjct: 484 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQE 543
Query: 119 EKERERQAKLAEEKMRKEEEEAK 141
EK R ++ K+ E+++R ++E K
Sbjct: 544 EKMRRQEEKMREQEVRLRQQEEK 566
Score = 35.4 bits (80), Expect = 0.055
Identities = 50/230 (21%), Positives = 106/230 (46%), Gaps = 31/230 (13%)
Query: 60 RVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVA-LKERIER-----RRSERAEQ 113
+++ ++ RK LL Q + + KE + + A L+ ++E R +++ E+
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 114 QRFRTEKE-RERQAKL---------AEEKMRKEEE-----EAKKRAEDD---AKKKKVLS 155
+ +R E++ +ER+ K+ EEKMR++EE E K R +++ K++K+
Sbjct: 289 KMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRE 348
Query: 156 -NMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQ 214
H + + E+KR + + RE + R E K + EE++R + + +
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-----WRQEEKIREQEEKIREQE 403
Query: 215 PSCPAR-EKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQK 263
+ EK E + + + E E + K+++Q+ +I +I ++
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEE 453
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 61.6 bits (148), Expect = 7e-10
Identities = 61/280 (21%), Positives = 134/280 (47%), Gaps = 43/280 (15%)
Query: 7 QEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDI 66
+E EE+ E+E E+EE +E E + E E+ + + ++ KI E E +
Sbjct: 380 RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQE---EKIREQEEKIREQ- 435
Query: 67 HRKRMEKDLLELQTLIDVHFEQRKKEEEEL------VALKERIERRRSERAEQQRFRTEK 120
K+M + ++ + E++++E+EE+ + +E I R++ + EQ++ R ++
Sbjct: 436 -EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQE 494
Query: 121 E----------------RERQAKL--AEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFG 162
E RE++ K+ EEK+R++EE+ +++ E ++++++ G
Sbjct: 495 EKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMG 554
Query: 163 GYLVK-AEQKRGKRQTG--REMKVRILSERKKPLDID---YMGEEQLRARSAWLPPSQPS 216
K EQ++ +RQ RE + +I +++K + + + EE++R + + +
Sbjct: 555 EQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEK 614
Query: 217 --------CPAREKAQELSDWIHQLESEKFDLMAKLKQQK 248
C EK QE + + + E + ++ +L+QQ+
Sbjct: 615 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 654
Score = 47.4 bits (111), Expect = 1e-05
Identities = 46/247 (18%), Positives = 119/247 (48%), Gaps = 30/247 (12%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
++QE + + EE+ E EE+ E+ E + E EE+ + K+ E + ++
Sbjct: 296 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE---------KMRRQEEMMWE 346
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERER 124
+ R +++++ + E+ ++ EE + +E+I + EQ++ R ++E+ +
Sbjct: 347 KEEKMRRQEEMMWEKE------EKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 400
Query: 125 QAKLAEEKMRKEEEEAKK-RAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKV 183
+ + E+ +++E+EAK R E+ ++++ ++ ++K+ RQ + +
Sbjct: 401 EEEKIREQEKRQEQEAKMWRQEEKIREQE-----------EKIREQEKKMWRQEEKIHEQ 449
Query: 184 RILSERKKPLDIDYM--GEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLM 241
+ E +K + + M EE++R + + + +EK ++ + + + E + D
Sbjct: 450 EKIREEEKRQEQEEMWRQEEKIREQEE-IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE 508
Query: 242 AKLKQQK 248
K+++Q+
Sbjct: 509 EKIREQE 515
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/174 (22%), Positives = 81/174 (46%), Gaps = 11/174 (6%)
Query: 7 QEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDI 66
QE + EE+ E+EE+ + E + E EE+ + KI E E + +
Sbjct: 500 QEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE---------KIREQEEMMQEQE 550
Query: 67 HRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQA 126
+ +++ ++ Q + E+ +++EE++ KE+I + + EQ+ E+E Q
Sbjct: 551 EKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQE 610
Query: 127 KLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
+ EEKM ++EE+ ++ E ++++ + V+ Q+ K Q +E
Sbjct: 611 Q--EEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/248 (22%), Positives = 120/248 (48%), Gaps = 16/248 (6%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEP-----VAEPEEERPKPSRPVVPPLIPPKIPEGE 59
+E+E +E + E +EEE +E EP + E EE+ K R + + + +
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 60 RVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTE 119
R+ + R++ E++ E Q + EQ+++ E++ ++++ R + ER EQQ R E
Sbjct: 299 RLRREQQLRRKQEEERREQQ---EERREQQERREQQEERREQQLRREQEERREQQ-LRRE 354
Query: 120 KERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGR 179
+E ER+ E+++R+E+EE ++R + +++++ L + +Q R ++Q R
Sbjct: 355 QEEERR----EQQLRREQEE-ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 409
Query: 180 EMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFD 239
E ++R + ++ + EE+ + + + + +E DW+ + E +
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKH--EQERREQRLKREQEERRDWLKREEETERH 467
Query: 240 LMAKLKQQ 247
+ KQQ
Sbjct: 468 EQERRKQQ 475
Score = 58.9 bits (141), Expect = 5e-09
Identities = 60/254 (23%), Positives = 120/254 (47%), Gaps = 38/254 (14%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPE---EPEPVAEPEEERPKPSRPVVPPLIPPKIPEGE 59
+ EQ++E+E+ E+ E+EE + E E+ER K + E E
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK--------RDQEEE 483
Query: 60 RVDF-----DDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQ 114
R + ++ R++ E+ +L+ + EQR K +EE L++R+ R+EQQ
Sbjct: 484 RRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL------RSEQQ 537
Query: 115 RFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGK 174
R ++ER Q EE+ R E+E ++R + + ++++ L+K E++R +
Sbjct: 538 LRREQEERREQLLKREEEKRLEQERREQRLKREQEERR----------DQLLKREEERRQ 587
Query: 175 RQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLE 234
++ RE + R L +R K +++ + +E+ R + + P E+ Q+L Q E
Sbjct: 588 QRLKREQEER-LEQRLKREEVERLEQEERREQRL-----KREEPEEERRQQLLKSEEQEE 641
Query: 235 SEKFDLMAKLKQQK 248
+ L + ++++
Sbjct: 642 RRQQQLRREQQERR 655
Score = 56.6 bits (135), Expect = 2e-08
Identities = 55/255 (21%), Positives = 123/255 (48%), Gaps = 35/255 (13%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
E+Q+ E+ + EEEE+ + E V EEE+ + P + + + +++
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE-RE 123
++ R+R E++ +QR + E++L R ++ R +Q+ R ++E RE
Sbjct: 285 ELRRERQEEE----------QQQQRLRREQQL-----RRKQEEERREQQEERREQQERRE 329
Query: 124 RQAKLAEEKMRKEEEEAK----KRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGR 179
+Q + E+++R+E+EE + +R +++ ++++ L + E++R ++Q R
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQLRR----------EQEEERREQQLRR 379
Query: 180 EMKVR----ILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLES 235
E ++R + E++ + E+QLR R L Q ++ +E + H+ +
Sbjct: 380 EQQLRREQQLRREQQLRREQQLRREQQLR-REQQLRREQQLRREQQLRREQEEERHEQKH 438
Query: 236 EKFDLMAKLKQQKYE 250
E+ +LK+++ E
Sbjct: 439 EQERREQRLKREQEE 453
Score = 55.1 bits (131), Expect = 7e-08
Identities = 67/279 (24%), Positives = 117/279 (41%), Gaps = 52/279 (18%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPE----EERPKPSRPVVPPLIPPKIP 56
+ + EE+ EE+ + E+E + EE + E E EER K R
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRR-----------Q 954
Query: 57 EGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKK--------EEEELVALKERIERRRS 108
E ER D ++ E+ LL + E+ KK +EEE + +ER +RRR
Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQ 1014
Query: 109 ERAEQQRFRTEKERERQAKLAE--EKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLV 166
E Q R + E ++E + L E EK R +E E + R E++ ++++
Sbjct: 1015 EWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE-------------- 1060
Query: 167 KAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQEL 226
EQ G+ + R R++ L+ Y EE+L+ L +P R++ +
Sbjct: 1061 --EQLLGEERETR---------RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQ 1109
Query: 227 SDWIHQLESEKFDLM--AKLKQQKYEINVLYNRISHAQK 263
+L+ E+ L+ + K+++ E+ Y Q+
Sbjct: 1110 CREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148
Score = 52.4 bits (124), Expect = 4e-07
Identities = 59/266 (22%), Positives = 120/266 (45%), Gaps = 38/266 (14%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVD 62
+ E +E +EE+ E++ E++E E + E EE R + R E E
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR-----------EQEEER 359
Query: 63 FDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE- 121
+ R+ E++ E Q + EQ+ + E++L +E+ RR + +Q+ R E++
Sbjct: 360 REQQLRREQEEERREQQ----LRREQQLRREQQL--RREQQLRREQQLRREQQLRREQQL 413
Query: 122 -RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGRE 180
RE+Q + ++ R++EEE ++ + ++++ L K EQ+ + RE
Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRL------------KREQEERRDWLKRE 461
Query: 181 MKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDL 240
+ + ++ + EE+ R R WL + RE+ + + + + E+ +
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRER--WLKLEEEE--RREQQERREQQLRREQEERRE- 516
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRK 266
+LK+Q+ E L R+ Q+ R+
Sbjct: 517 -QRLKRQEEE-ERLQQRLRSEQQLRR 540
Score = 51.6 bits (122), Expect = 7e-07
Identities = 52/246 (21%), Positives = 107/246 (43%), Gaps = 28/246 (11%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
EE++ + + ++ EEE+ E+ E E+ R + R + E +R
Sbjct: 836 EEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEE-------ERKRRRHT 888
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERER 124
+ +++ L + Q L+ +EEEE + +ER +RRR E+ Q R + ++E
Sbjct: 889 LYAKPALQEQLRKEQQLL--------QEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
Query: 125 QAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVR 184
+ L EE+ ++ +E +++ D K ++ + E+ +R+ RE K R
Sbjct: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQL---------LGEEPEKRRRQEREKKYR 991
Query: 185 ILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKL 244
E ++ + E + R R W + +++ Q+ + + + E EK L +
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEW----ERQYRKKDELQQEEEQLLREEREKRRLQERE 1047
Query: 245 KQQKYE 250
+Q + E
Sbjct: 1048 RQYREE 1053
Score = 50.4 bits (119), Expect = 2e-06
Identities = 73/328 (22%), Positives = 139/328 (42%), Gaps = 62/328 (18%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
EE+E + E+ E+ +E+E E E + + EE+ + R + E ER
Sbjct: 909 EEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREERE------KRRRQERERQYRK 962
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKK--------EEEELVALKERIERRRSE------- 109
D ++ E+ LL + E+ KK +EEE + +ER +RRR E
Sbjct: 963 DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022
Query: 110 -----RAEQQRFRTEKE------RERQAKLAEEKMRKEEE-------EAKKRAEDDAKKK 151
+ E+Q R E+E RERQ + EE++++EEE E ++R E + + +
Sbjct: 1023 KDELQQEEEQLLREEREKRRLQERERQYR-EEEELQQEEEQLLGEERETRRRQELERQYR 1081
Query: 152 KVLSNMGAHFGGYLVKAEQKRGKRQTGREMK---------VRILSE-----RKKPLDIDY 197
K + L + +KR +++ R+ + ++L E R++ L+ Y
Sbjct: 1082 KE-EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQY 1140
Query: 198 MGEEQLRARSAWLPPSQPSCPARE-------KAQELSDWIHQLESEKFDLMAKLKQQKYE 250
EE+++ L +P R+ + +EL QL E+ + + ++++Y
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYR 1200
Query: 251 INVLYNRISHAQKFRKGAGKGRVGGRWK 278
R Q++R + + +W+
Sbjct: 1201 EEEELQRQKRKQRYRDEDQRSDLKWQWE 1228
Score = 50.1 bits (118), Expect = 2e-06
Identities = 64/289 (22%), Positives = 122/289 (42%), Gaps = 47/289 (16%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIP--EGERVD 62
EE+ E+E+ E+ E+EE ++ + EE R + + + ++ E ER++
Sbjct: 554 EEKRLEQERREQRLKREQEERRDQL--LKREEERRQQRLKREQEERLEQRLKREEVERLE 611
Query: 63 FDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQ--------- 113
++ +R++++ E + +Q K EE+ ++++ R + ER EQ
Sbjct: 612 QEERREQRLKREEPE-----EERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Query: 114 ---QRFRTEKERE-RQAKLAEEKMRKEEEEAKKR---------AEDDAKKKKVLSNMGAH 160
QR + E E E R+ +LAEE+ + E K R +E DA++ KV S
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQ 726
Query: 161 FG---------------GYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRA 205
G L E++R RQ E + R + + + + G ++L A
Sbjct: 727 EGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSA 786
Query: 206 RSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVL 254
R + A E+ Q ++ + E EK + ++++ E+ L
Sbjct: 787 RPPLREQRERQLRAEERQQREQRFLPE-EEEKEQRRRQRREREKELQFL 834
Score = 50.1 bits (118), Expect = 2e-06
Identities = 62/272 (22%), Positives = 114/272 (41%), Gaps = 46/272 (16%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
+ EEQ EE+ + E E + EE E E E+ L+ + R
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQ------------LLGEERETRRR 1073
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKE-------------EEELVALKERIERRR 107
+ + +RK E E Q L + ++R++E EEE + +ER +RRR
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
Query: 108 SERAEQQRFRTEKERERQAKLAE--EKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYL 165
E Q R E ++E + L E EK R++E E + R E++ ++++ L
Sbjct: 1134 QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE----------EQL 1183
Query: 166 VKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPS-------CP 218
++ EQ++ +++ R+ + +R+K +++ + W P + + C
Sbjct: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCK 1243
Query: 219 AREKAQ--ELSDWIHQLESEKFDLMAKLKQQK 248
RE Q +L D + + DL L +Q+
Sbjct: 1244 GRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ 1275
Score = 49.7 bits (117), Expect = 3e-06
Identities = 55/213 (25%), Positives = 93/213 (43%), Gaps = 29/213 (13%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVD 62
++E Q EEE+ + EEE+ + AE + ER + PPL E
Sbjct: 743 ESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPL-----REQRERQ 797
Query: 63 FDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQR-----FR 117
R++ E+ L + + QR++ E+EL L+E + +R ERA+Q + +
Sbjct: 798 LRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQ 857
Query: 118 TEKERER-QAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQ 176
++ER R Q + ++K R + EE +KR K L EQ R ++Q
Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQ-------------EQLRKEQQ 904
Query: 177 TGREMKVRILSE-----RKKPLDIDYMGEEQLR 204
+E + + E R++ + Y EEQL+
Sbjct: 905 LLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937
Score = 48.5 bits (114), Expect = 6e-06
Identities = 44/155 (28%), Positives = 79/155 (50%), Gaps = 21/155 (13%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEA--PEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEG 58
+ + EEQ+ ++ + + EEE++ E E E +P R K E
Sbjct: 1470 LQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPER---------KFLEE 1520
Query: 59 ERVDFDDIHRK-RMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFR 117
E+ +HR+ R K L E Q L Q+++++ + +E E+ R ER EQQ R
Sbjct: 1521 EQ----QLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREE--EQLRQEREEQQLSR 1574
Query: 118 TEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKK 152
+ER+R+ +L E+K+R++E+E +K ED+ + ++
Sbjct: 1575 --QERDRKFRLEEQKVRRQEQE-RKFMEDEQQLRR 1606
Score = 45.1 bits (105), Expect = 7e-05
Identities = 62/283 (21%), Positives = 122/283 (43%), Gaps = 46/283 (16%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVD 62
D + + EEEQ +E E++ E E E++ + R + E +++
Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE------RKFLQEEQQLR 1717
Query: 63 FDDIHRKRMEKDLLELQTLIDVHFEQRKK----EEEELVALKERIERRRSE-----RAEQ 113
++ RK E++ L +T + Q + EEE+L +E + RR E R E+
Sbjct: 1718 RQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEE 1777
Query: 114 QRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRG 173
Q + +E++ +++ ++ K R+EE+ ++R E + ++ G Y + EQ +
Sbjct: 1778 QLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQ-------RDGKYRWEEEQLQL 1830
Query: 174 KRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQL 233
+ E + R+ ER D Y EEQ + +R + QEL W +
Sbjct: 1831 E-----EQEQRLRQER----DRQYRAEEQFATQE----------KSRREEQEL--WQEEE 1869
Query: 234 ESEKFDLMAKLKQQ---KYEINVLYNRISHAQKFRKGAGKGRV 273
+ + + KL+++ + + +R K ++G G GR+
Sbjct: 1870 QKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRL 1912
Score = 44.7 bits (104), Expect = 9e-05
Identities = 51/203 (25%), Positives = 91/203 (44%), Gaps = 22/203 (10%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
E+QE + EQ + + PEE + E ++E + R + E+
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQ 1332
Query: 65 DIHRK-RMEKDLLELQTLIDVHFEQRKKE--EEELVALKERIERRRSERAEQQRFRTEKE 121
+ RK R E+ LL+ + + ++R ++ EEEL E+ R E+QR R + E
Sbjct: 1333 ETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL----RHQEQGRKFLEEEQRLRRQ-E 1387
Query: 122 RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREM 181
RER+ E+++R +E E + R + D K ++ + + Q+R ++ E
Sbjct: 1388 RERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQL----------SRQERDRKFREEEQ 1437
Query: 182 KVRILSERKKPLDIDYMGEEQLR 204
+VR +K L+ E+QLR
Sbjct: 1438 QVRRQERERKFLE----EEQQLR 1456
Score = 44.3 bits (103), Expect = 1e-04
Identities = 61/269 (22%), Positives = 115/269 (42%), Gaps = 46/269 (17%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEER--------PKPSRPVVPPLIPPKIP 56
EEQE ++ E + EEEE ++ + E++R P+ V + K
Sbjct: 1186 EEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR 1245
Query: 57 EGER---VDFDDIHRKRMEKDLLEL---QTLIDVHFEQRKKE-------EEELVALKERI 103
E E+ ++ + ++ ++DL L Q D E+R+ + EEE + +E+
Sbjct: 1246 ENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQK 1305
Query: 104 ERRRSERA---EQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAH 160
E +R +R E+Q R E+E +R+ + + K R+EE+ ++R E ++
Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRR---------- 1355
Query: 161 FGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAR 220
Q+R ++ RE ++R + +K L+ + Q R R Q C R
Sbjct: 1356 ---------QERDRK--FREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 221 EKAQELSDWIHQLESEKFDLMAKLKQQKY 249
E+ Q D + E+ L + + +K+
Sbjct: 1405 EQ-QLRQDRDRKFREEEQQLSRQERDRKF 1432
Score = 44.3 bits (103), Expect = 1e-04
Identities = 66/279 (23%), Positives = 121/279 (43%), Gaps = 25/279 (8%)
Query: 2 SDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKI---PEG 58
S E+Q EE+ E+ +E + E E + + EE+P + ++ +G
Sbjct: 1314 SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQG 1373
Query: 59 ERVDFDDIHRKRMEKD---LLELQTLIDVHFEQRKKEEEELVALKE-----RIERRRSER 110
+ ++ +R E++ L E Q L EQ+ +++ + +E R ER R R
Sbjct: 1374 RKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFR 1433
Query: 111 AEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQ 170
E+Q+ R +ERER+ L EE+ ++E K R E+ +++ + E+
Sbjct: 1434 EEEQQVR-RQERERKF-LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEE 1491
Query: 171 KRGKRQTG----REMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQEL 226
++ +RQ RE ++R +K L+ + Q R R +L Q + + QE
Sbjct: 1492 QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRK-FLQEEQ-----QLRRQER 1545
Query: 227 SDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFR 265
Q KF +L+Q++ E + +R +KFR
Sbjct: 1546 GQQRRQDRDRKFREEEQLRQEREEQQL--SRQERDRKFR 1582
Score = 44.3 bits (103), Expect = 1e-04
Identities = 53/215 (24%), Positives = 100/215 (46%), Gaps = 33/215 (15%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
EEQ+ ++ E + E+E++ + E + +ER + R L + +
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQ-EGQQQLRQERDRKFREDEQLL--------QEREEQ 1634
Query: 65 DIHRKRMEKDLLELQTLIDV--------HFEQRK-KEEEELVALKERIERRRSER----- 110
+HR+ ++ LE + + H RK +EEE+L+ E + RR ER
Sbjct: 1635 QLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694
Query: 111 AEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFG-GYLVKAE 169
E+Q+ R + ERER+ E+++R++E E K R E+ +++ + +++ E
Sbjct: 1695 EEEQQLRRQ-ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753
Query: 170 QKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLR 204
Q R +R+ E ++ R++ D + EEQLR
Sbjct: 1754 QLRPERE---EQQL-----RRQERDRKFREEEQLR 1780
Score = 42.7 bits (99), Expect = 3e-04
Identities = 49/223 (21%), Positives = 98/223 (43%), Gaps = 34/223 (15%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPE-PVAEPEEERPKPSRPVVPPLIPPKIPEGERV 61
D E + Q EEE + + +E E +AE EE+ K R + + +R
Sbjct: 118 DQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERL--------EQRDRQRR 169
Query: 62 DFDDIHRKRMEKDLLELQTLIDVHFEQRKKEE------EELVALKERIERRRSERAEQQR 115
D +++ R+R E E + + + K E EE + +E +E RR R E+Q+
Sbjct: 170 D-EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ 228
Query: 116 FRTEKE--------------RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHF 161
R E++ RE + EEK+++EE + ++ +++ ++ + L
Sbjct: 229 QRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELR- 287
Query: 162 GGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLR 204
+ E+++ +++ RE ++R E ++ + E+Q R
Sbjct: 288 ---RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Score = 40.8 bits (94), Expect = 0.001
Identities = 57/223 (25%), Positives = 97/223 (43%), Gaps = 22/223 (9%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEE--RPKPSRPVVPPLIPPKIPEG 58
+ + EEQ ++ + + EEE E+ E E+ R + R + + E
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQER 1404
Query: 59 ERVDFDDIHRKRMEKDLLELQTLIDVHF----EQRKKEEEELVALKE----RIERRRSER 110
E+ D RK E++ + D F +Q +++E E L+E R ER R R
Sbjct: 1405 EQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFR 1464
Query: 111 AEQQRFRTEKERERQAKLAEEKMRK--EEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKA 168
E+Q +ERE Q +E+ RK EEE+ +R E D K ++ +L +
Sbjct: 1465 EEEQLL---QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE 1521
Query: 169 E----QKRGKRQTGREMKVRIL---SERKKPLDIDYMGEEQLR 204
+ Q+R ++ E ++R +R++ D + EEQLR
Sbjct: 1522 QQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLR 1564
Score = 33.5 bits (75), Expect = 0.21
Identities = 28/144 (19%), Positives = 65/144 (45%), Gaps = 26/144 (18%)
Query: 10 EEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRK 69
+ Q E++ E + E EP ++R + R ++ EGE ++
Sbjct: 112 DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQER---------ELAEGEE---QSEKQE 159
Query: 70 RMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLA 129
R+E+ R++ +EEL ++ + R RAE+++ ++ K E +
Sbjct: 160 RLEQ-------------RDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPD 206
Query: 130 EEKMRKEE-EEAKKRAEDDAKKKK 152
EE++R+ E E +++ ++ ++++
Sbjct: 207 EEQLRRRELLELRRKGREEKQQQR 230
Score = 32.3 bits (72), Expect = 0.47
Identities = 28/139 (20%), Positives = 60/139 (43%), Gaps = 1/139 (0%)
Query: 100 KERIERRRSERAEQQRFR-TEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMG 158
KE + + R + +Q+RF +++ E + + R+E+E E+ ++K++ L
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 159 AHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCP 218
+ +++ + + R + L K ++ EEQLR R +
Sbjct: 166 RQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREE 225
Query: 219 AREKAQELSDWIHQLESEK 237
+++ +E D + Q E EK
Sbjct: 226 KQQQRRERQDRVFQEEEEK 244
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 59.7 bits (143), Expect = 3e-09
Identities = 62/273 (22%), Positives = 128/273 (46%), Gaps = 22/273 (8%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVA-EPEEERPKPSRPVVPPLIPPKIPEGERV 61
+ E E ++ EEE +EE ++ E + + EEER + + + +R
Sbjct: 734 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 793
Query: 62 DFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE 121
+ R+R E++ + + + E+R++EEEE +E + ++ E A+ R +E
Sbjct: 794 QEIALRRQREEEERQQQEEALR-RLEERRREEEERRKQEELLRKQEEEAAKWAR----EE 848
Query: 122 RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREM 181
E Q +L E ++R EEE A+ R E++ +K+K L + + ++ +RQ +E
Sbjct: 849 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELE---------VQRQKELMRQRQQQQEA 899
Query: 182 KVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEK-FDL 240
R+ ++++ + + +L + S W S + + L++ I +LE E+ L
Sbjct: 900 LRRLQQQQQQ----QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE-IQKLEEERERQL 954
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRV 273
+ ++Q+ E+ + Q+ +K +G G V
Sbjct: 955 REEQRRQQRELMKALQQ-QQQQQQQKLSGWGNV 986
Score = 47.0 bits (110), Expect = 2e-05
Identities = 40/189 (21%), Positives = 84/189 (44%), Gaps = 28/189 (14%)
Query: 78 LQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEE 137
L+ L + + K E+E + R +R ER Q+ R ++E + + EE+ R+EE
Sbjct: 717 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 776
Query: 138 EEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDY 197
EE +R +++A +++ + Q+ + + +E +R L ER++
Sbjct: 777 EELARRKQEEALRRQREQEIALR--------RQREEEERQQQEEALRRLEERRRE----- 823
Query: 198 MGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNR 257
EE+ R + L R++ +E + W + E + +L++ + + R
Sbjct: 824 --EEERRKQEELL---------RKQEEEAAKWAREEE----EAQRRLEENRLRMEEEAAR 868
Query: 258 ISHAQKFRK 266
+ H ++ RK
Sbjct: 869 LRHEEEERK 877
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/156 (25%), Positives = 72/156 (46%), Gaps = 34/156 (21%)
Query: 70 RMEKDLLELQTLIDVHFEQRKKEE------EELVALKERIERRRSERAEQQRFRTEK--E 121
++E++ E + E+RK++E EE++ ++ ER+R E E R + E+
Sbjct: 730 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 789
Query: 122 RERQAKLAEEKMRKEEE-----------EAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQ 170
R+R+ ++A + R+EEE E ++R E++ +K++ L L K E+
Sbjct: 790 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL----------LRKQEE 839
Query: 171 KRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRAR 206
+ K E R L E + ++ EE R R
Sbjct: 840 EAAKWAREEEEAQRRLEENRLRME-----EEAARLR 870
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 59.7 bits (143), Expect = 3e-09
Identities = 62/273 (22%), Positives = 128/273 (46%), Gaps = 22/273 (8%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVA-EPEEERPKPSRPVVPPLIPPKIPEGERV 61
+ E E ++ EEE +EE ++ E + + EEER + + + +R
Sbjct: 761 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 820
Query: 62 DFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE 121
+ R+R E++ + + + E+R++EEEE +E + ++ E A+ R +E
Sbjct: 821 QEIALRRQREEEERQQQEEALR-RLEERRREEEERRKQEELLRKQEEEAAKWAR----EE 875
Query: 122 RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREM 181
E Q +L E ++R EEE A+ R E++ +K+K L + + ++ +RQ +E
Sbjct: 876 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELE---------VQRQKELMRQRQQQQEA 926
Query: 182 KVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEK-FDL 240
R+ ++++ + + +L + S W S + + L++ I +LE E+ L
Sbjct: 927 LRRLQQQQQQ----QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE-IQKLEEERERQL 981
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRV 273
+ ++Q+ E+ + Q+ +K +G G V
Sbjct: 982 REEQRRQQRELMKALQQ-QQQQQQQKLSGWGNV 1013
Score = 47.0 bits (110), Expect = 2e-05
Identities = 40/189 (21%), Positives = 84/189 (44%), Gaps = 28/189 (14%)
Query: 78 LQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEE 137
L+ L + + K E+E + R +R ER Q+ R ++E + + EE+ R+EE
Sbjct: 744 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 803
Query: 138 EEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDY 197
EE +R +++A +++ + Q+ + + +E +R L ER++
Sbjct: 804 EELARRKQEEALRRQREQEIALR--------RQREEEERQQQEEALRRLEERRRE----- 850
Query: 198 MGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNR 257
EE+ R + L R++ +E + W + E + +L++ + + R
Sbjct: 851 --EEERRKQEELL---------RKQEEEAAKWAREEE----EAQRRLEENRLRMEEEAAR 895
Query: 258 ISHAQKFRK 266
+ H ++ RK
Sbjct: 896 LRHEEEERK 904
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/156 (25%), Positives = 72/156 (46%), Gaps = 34/156 (21%)
Query: 70 RMEKDLLELQTLIDVHFEQRKKEE------EELVALKERIERRRSERAEQQRFRTEK--E 121
++E++ E + E+RK++E EE++ ++ ER+R E E R + E+
Sbjct: 757 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 816
Query: 122 RERQAKLAEEKMRKEEE-----------EAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQ 170
R+R+ ++A + R+EEE E ++R E++ +K++ L L K E+
Sbjct: 817 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL----------LRKQEE 866
Query: 171 KRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRAR 206
+ K E R L E + ++ EE R R
Sbjct: 867 EAAKWAREEEEAQRRLEENRLRME-----EEAARLR 897
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 59.7 bits (143), Expect = 3e-09
Identities = 62/273 (22%), Positives = 128/273 (46%), Gaps = 22/273 (8%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVA-EPEEERPKPSRPVVPPLIPPKIPEGERV 61
+ E E ++ EEE +EE ++ E + + EEER + + + +R
Sbjct: 740 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 799
Query: 62 DFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE 121
+ R+R E++ + + + E+R++EEEE +E + ++ E A+ R +E
Sbjct: 800 QEIALRRQREEEERQQQEEALR-RLEERRREEEERRKQEELLRKQEEEAAKWAR----EE 854
Query: 122 RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREM 181
E Q +L E ++R EEE A+ R E++ +K+K L + + ++ +RQ +E
Sbjct: 855 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELE---------VQRQKELMRQRQQQQEA 905
Query: 182 KVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEK-FDL 240
R+ ++++ + + +L + S W S + + L++ I +LE E+ L
Sbjct: 906 LRRLQQQQQQ----QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE-IQKLEEERERQL 960
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRV 273
+ ++Q+ E+ + Q+ +K +G G V
Sbjct: 961 REEQRRQQRELMKALQQ-QQQQQQQKLSGWGNV 992
Score = 47.0 bits (110), Expect = 2e-05
Identities = 40/189 (21%), Positives = 84/189 (44%), Gaps = 28/189 (14%)
Query: 78 LQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEE 137
L+ L + + K E+E + R +R ER Q+ R ++E + + EE+ R+EE
Sbjct: 723 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782
Query: 138 EEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDY 197
EE +R +++A +++ + Q+ + + +E +R L ER++
Sbjct: 783 EELARRKQEEALRRQREQEIALR--------RQREEEERQQQEEALRRLEERRRE----- 829
Query: 198 MGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNR 257
EE+ R + L R++ +E + W + E + +L++ + + R
Sbjct: 830 --EEERRKQEELL---------RKQEEEAAKWAREEE----EAQRRLEENRLRMEEEAAR 874
Query: 258 ISHAQKFRK 266
+ H ++ RK
Sbjct: 875 LRHEEEERK 883
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/156 (25%), Positives = 72/156 (46%), Gaps = 34/156 (21%)
Query: 70 RMEKDLLELQTLIDVHFEQRKKEE------EELVALKERIERRRSERAEQQRFRTEK--E 121
++E++ E + E+RK++E EE++ ++ ER+R E E R + E+
Sbjct: 736 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 795
Query: 122 RERQAKLAEEKMRKEEE-----------EAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQ 170
R+R+ ++A + R+EEE E ++R E++ +K++ L L K E+
Sbjct: 796 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL----------LRKQEE 845
Query: 171 KRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRAR 206
+ K E R L E + ++ EE R R
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRME-----EEAARLR 876
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 59.7 bits (143), Expect = 3e-09
Identities = 62/273 (22%), Positives = 128/273 (46%), Gaps = 22/273 (8%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVA-EPEEERPKPSRPVVPPLIPPKIPEGERV 61
+ E E ++ EEE +EE ++ E + + EEER + + + +R
Sbjct: 740 ERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQRE 799
Query: 62 DFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE 121
+ R+R E++ + + + E+R++EEEE +E + ++ E A+ R +E
Sbjct: 800 QEIALRRQREEEERQQQEEALR-RLEERRREEEERRKQEELLRKQEEEAAKWAR----EE 854
Query: 122 RERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREM 181
E Q +L E ++R EEE A+ R E++ +K+K L + + ++ +RQ +E
Sbjct: 855 EEAQRRLEENRLRMEEEAARLRHEEEERKRKELE---------VQRQKELMRQRQQQQEA 905
Query: 182 KVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEK-FDL 240
R+ ++++ + + +L + S W S + + L++ I +LE E+ L
Sbjct: 906 LRRLQQQQQQ----QQLAQMKLPSSSTWGQQSNTTACQSQATLSLAE-IQKLEEERERQL 960
Query: 241 MAKLKQQKYEINVLYNRISHAQKFRKGAGKGRV 273
+ ++Q+ E+ + Q+ +K +G G V
Sbjct: 961 REEQRRQQRELMKALQQ-QQQQQQQKLSGWGNV 992
Score = 47.0 bits (110), Expect = 2e-05
Identities = 40/189 (21%), Positives = 84/189 (44%), Gaps = 28/189 (14%)
Query: 78 LQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEE 137
L+ L + + K E+E + R +R ER Q+ R ++E + + EE+ R+EE
Sbjct: 723 LEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREE 782
Query: 138 EEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDY 197
EE +R +++A +++ + Q+ + + +E +R L ER++
Sbjct: 783 EELARRKQEEALRRQREQEIALR--------RQREEEERQQQEEALRRLEERRRE----- 829
Query: 198 MGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNR 257
EE+ R + L R++ +E + W + E + +L++ + + R
Sbjct: 830 --EEERRKQEELL---------RKQEEEAAKWAREEE----EAQRRLEENRLRMEEEAAR 874
Query: 258 ISHAQKFRK 266
+ H ++ RK
Sbjct: 875 LRHEEEERK 883
Score = 40.0 bits (92), Expect = 0.002
Identities = 39/156 (25%), Positives = 72/156 (46%), Gaps = 34/156 (21%)
Query: 70 RMEKDLLELQTLIDVHFEQRKKEE------EELVALKERIERRRSERAEQQRFRTEK--E 121
++E++ E + E+RK++E EE++ ++ ER+R E E R + E+
Sbjct: 736 KLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALR 795
Query: 122 RERQAKLAEEKMRKEEE-----------EAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQ 170
R+R+ ++A + R+EEE E ++R E++ +K++ L L K E+
Sbjct: 796 RQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL----------LRKQEE 845
Query: 171 KRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRAR 206
+ K E R L E + ++ EE R R
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRME-----EEAARLR 876
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 58.9 bits (141), Expect = 5e-09
Identities = 57/194 (29%), Positives = 85/194 (43%), Gaps = 41/194 (21%)
Query: 2 SDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERV 61
++ E Q +Q EE EEE A E VA+ EE + + + + ++ E +R+
Sbjct: 108 AEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIEREVLRRVEEAKRI 167
Query: 62 DFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKE 121
MEK LLE E ++ + EL A K R E R++R E +R E
Sbjct: 168 ---------MEKQLLE---------ELERQRQAELAAQKAREEEERAKREELERILEENN 209
Query: 122 R---ERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTG 178
R E QAKLAEE++R EE+ K E +K EQ+R +RQ
Sbjct: 210 RKIAEAQAKLAEEQLRIVEEQRKIHEE-------------------RMKLEQER-QRQQK 249
Query: 179 REMKVRILSERKKP 192
E K+ + + +P
Sbjct: 250 EEQKIILGKGKSRP 263
Score = 42.7 bits (99), Expect = 3e-04
Identities = 37/129 (28%), Positives = 63/129 (48%), Gaps = 11/129 (8%)
Query: 87 EQRKKEEEELVALKERIERRRSERAEQQRFRTEKER---ERQAKLAEEKMRKEEEEAKK- 142
E++K+EEEE A ER + R + E++ E R E AK EE++ K ++E ++
Sbjct: 97 EKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEELVAKRVEEELEKRKDEIERE 156
Query: 143 --RAEDDAKK---KKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDY 197
R ++AK+ K++L + L + + + + RE RIL E + +
Sbjct: 157 VLRRVEEAKRIMEKQLLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQ 216
Query: 198 --MGEEQLR 204
+ EEQLR
Sbjct: 217 AKLAEEQLR 225
Score = 34.3 bits (77), Expect = 0.12
Identities = 38/175 (21%), Positives = 81/175 (46%), Gaps = 26/175 (14%)
Query: 88 QRKKEEEELVALKERIE-------RRRSERAEQQRFRTEK--ERERQAKLAEEKMRKE-- 136
+R+++ E + +RI+ +R S +Q+R EK E ERQ K+ ++++ ++
Sbjct: 67 RRERDRERASSPPDRIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLI 126
Query: 137 EEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDID 196
EEE +R E+ K+ V+ E ++ K + RE+ +R + E K+ ++
Sbjct: 127 EEETARRVEELVAKR--------------VEEELEKRKDEIEREV-LRRVEEAKRIMEKQ 171
Query: 197 YMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEI 251
+ E + + ++ R K +EL + + + + AKL +++ I
Sbjct: 172 LLEELERQRQAELAAQKAREEEERAKREELERILEENNRKIAEAQAKLAEEQLRI 226
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 57.4 bits (137), Expect = 1e-08
Identities = 62/277 (22%), Positives = 125/277 (45%), Gaps = 42/277 (15%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPP------LIPPK 54
M + E+ +EE+ +EE E+E +E E +EE+ + + K
Sbjct: 447 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEK 506
Query: 55 IPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERI----------E 104
I E E++ ++ KR E++ + Q E++ +E+EE+ KE+I E
Sbjct: 507 IHEQEKIREEE---KRQEQEEMWRQ-------EEKIREQEEIWRQKEKIHEQEEKIRKQE 556
Query: 105 RRRSERAEQQRFRTEKERERQAKL--AEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFG 162
+ + E+ + EK RE++ K+ EEK+R++EE+ +++ E +++++ G
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 163 GYLVK-----------AEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLP 211
K E+ R + + RE + +I + +K + + M +EQ W
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ--EEKMW-E 673
Query: 212 PSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQK 248
+ C EK QE + + + E + ++ +L+QQ+
Sbjct: 674 QEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQE 710
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/249 (18%), Positives = 119/249 (47%), Gaps = 27/249 (10%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
++QE + + EE+ E EE+ E+ E + E EE+ + K+ E + ++
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEE---------KMRRQEEMMWE 407
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERER 124
+ R +++++ + E+ +++EE + +E+I + EQ++ R ++E+ +
Sbjct: 408 KEEKMRRQEEMMWEKE------EKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 461
Query: 125 QAKLAEEKMRKEEEEAKK-RAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKV 183
+ + E+ +++E+EAK R E+ ++++ + + E+K +++ +
Sbjct: 462 EEEKIREQEKRQEQEAKMWRQEEKIREQE----------EKIREQEEKMWRQEEKIHEQE 511
Query: 184 RILSERKKPLDID-YMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMA 242
+I E K+ + + EE++R + + EK ++ + + + E + D
Sbjct: 512 KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE 571
Query: 243 KLKQQKYEI 251
K+++Q+ ++
Sbjct: 572 KIREQEEKV 580
Score = 44.3 bits (103), Expect = 1e-04
Identities = 43/181 (23%), Positives = 85/181 (46%), Gaps = 15/181 (8%)
Query: 6 EQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDD 65
EQE + + EE+ +EE+ ++ E + E EE+ + KI E E +
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEE---------KIREQEEKIREQ 597
Query: 66 IHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQ----RFRTEKE 121
+ R ++++ + Q E++ E+EE + +E RR+ E+ +Q R + EK
Sbjct: 598 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKI 657
Query: 122 RERQAKLAE--EKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGR 179
RE++ + E EKM ++EE+ ++ E ++++ + V+ Q+ K Q +
Sbjct: 658 REQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQ 717
Query: 180 E 180
E
Sbjct: 718 E 718
Score = 35.0 bits (79), Expect = 0.072
Identities = 40/193 (20%), Positives = 88/193 (45%), Gaps = 26/193 (13%)
Query: 90 KKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAE--EKMRKEEEEAKKRAEDD 147
+++EE++ +E+I+ + EQ+ EK RE++ K+ E EKMR++EE ++ E
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQE----EKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412
Query: 148 AKKKKVLSNMGAHFGGYLVKAEQKRGKRQT--GREMKVRILSERKKPLDIDYMGEEQLRA 205
++++++ K E+ R + + +E K+R L E+ M E++
Sbjct: 413 RRQEEMMWE----------KEEKMRRQEEMMWEKEEKIRELEEK--------MHEQEKIR 454
Query: 206 RSAWLPPSQPSCPAREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFR 265
+ +EK QE + + E + + K+++Q+ ++ +I +K R
Sbjct: 455 EQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIR 514
Query: 266 KGAGKGRVGGRWK 278
+ + W+
Sbjct: 515 EEEKRQEQEEMWR 527
Score = 28.1 bits (61), Expect = 8.8
Identities = 37/194 (19%), Positives = 87/194 (44%), Gaps = 31/194 (15%)
Query: 60 RVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVA-LKERIERRRS-ERAEQQRFR 117
+++ ++ RK LL Q + + KE + + A L+ ++E R QQ+
Sbjct: 302 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 361
Query: 118 TEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQT 177
+E + + EEK++++EE+ +++ E ++ ++++ +RQ
Sbjct: 362 KMWRQEEKIQEWEEKIQEQEEKIREQEEK-------------------IREQEEKMRRQ- 401
Query: 178 GREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQELSDWIHQLESEK 237
EM + ++ ++ + EE++R + + + EK +EL + +H E EK
Sbjct: 402 -EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE------EKIRELEEKMH--EQEK 452
Query: 238 FDLMAKLKQQKYEI 251
+ +Q++ +I
Sbjct: 453 IREQEEKRQEEEKI 466
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 57.0 bits (136), Expect = 2e-08
Identities = 71/274 (25%), Positives = 114/274 (41%), Gaps = 76/274 (27%)
Query: 3 DTEEQEYEEEQP--------------EEEAAEEEEE-----------APEEPEPVAEPEE 37
D E++E EEE+P EE+ E +EE + EEP+ EE
Sbjct: 187 DKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQ----EE 242
Query: 38 ERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELV 97
ER + S +I E+++ +D R E+ LE + + EQ KK +E
Sbjct: 243 EREQGS---------DEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERA 293
Query: 98 ALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNM 157
++ + ER ++ E+ RE + + AEE+ R +EEE KRA ++ ++
Sbjct: 294 RIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE--KRAAEERQR------- 344
Query: 158 GAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSC 217
+K E+KR E + RI E K+ EE+ RAR+ ++
Sbjct: 345 --------IKEEEKR-----AAEERQRIKEEEKR------AAEERQRARAEEEEKAKVEE 385
Query: 218 PAREKAQELSDWIHQLESEKFDLM-AKLKQQKYE 250
R K QLE +K + K+K +K E
Sbjct: 386 QKRNK---------QLEEKKHAMQETKIKGEKVE 410
Score = 50.4 bits (119), Expect = 2e-06
Identities = 32/104 (30%), Positives = 62/104 (59%), Gaps = 12/104 (11%)
Query: 53 PKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEE---ELVALKERIERRRSE 109
P++ G+R++ ++ R+R E + E + L ++K++E EL LK++ E RR
Sbjct: 528 PQVEAGKRLE--ELRRRRGETESEEFEKL-------KQKQQEAALELEELKKKREERRKV 578
Query: 110 RAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKV 153
E+++ R ++E +R+ + EEK R +EE ++RAE K++K+
Sbjct: 579 LEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKM 622
Score = 48.1 bits (113), Expect = 8e-06
Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 20/164 (12%)
Query: 1 MSDTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGER 60
MS Q EE +EE E+ + E + E ++ER + R + + E ER
Sbjct: 226 MSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARL------EAEERER 279
Query: 61 VDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSER---------- 110
+ + + E+ +E + E+ ++E EE ++E +R ER
Sbjct: 280 IKAEQDKKIADERARIEAEEKAAAQ-ERERREAEERERMREEEKRAAEERQRIKEEEKRA 338
Query: 111 -AEQQRFRTEKER--ERQAKLAEEKMRKEEEEAKKRAEDDAKKK 151
E+QR + E++R E + ++ EE+ R EE + RAE++ K K
Sbjct: 339 AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAK 382
Score = 41.6 bits (96), Expect = 8e-04
Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 7/104 (6%)
Query: 57 EGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKK-EEEELVALKERIERRRSERAEQQR 115
E E +F+ + +K+ E LEL+ L E+RK EEEE +E +R+ E E++R
Sbjct: 545 ETESEEFEKLKQKQQEA-ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR 603
Query: 116 FRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGA 159
+ E ER R+A+ AE++ + E+ DD K K + G+
Sbjct: 604 LKEEIER-RRAEAAEKRQKMPED----GLSDDKKPFKCFTPKGS 642
Score = 39.7 bits (91), Expect = 0.003
Identities = 60/265 (22%), Positives = 109/265 (41%), Gaps = 31/265 (11%)
Query: 2 SDTEEQEYEEEQ---PEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEG 58
++ E+ EEE+ E + +EEE+ E + EE+R R + E
Sbjct: 311 AEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 370
Query: 59 ERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRT 118
+R ++ + ++E+ Q H Q K + E V K + ++A++ + +T
Sbjct: 371 QRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQT 430
Query: 119 -----------EKERERQAKLAEEK--MRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYL 165
K + ++ KL E+K +KEE + +K +D K++V S M G
Sbjct: 431 AVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTE 490
Query: 166 VKAEQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCPAREKAQE 225
VK++ G+ T + R G + + A P A ++ +E
Sbjct: 491 VKSQ--NGEFMTHKLKHTENTFSRPG-------GRASVDTKEA---EGAPQVEAGKRLEE 538
Query: 226 LSDWIHQLESEKFDLMAKLKQQKYE 250
L + ESE+F+ KLKQ++ E
Sbjct: 539 LRRRRGETESEEFE---KLKQKQQE 560
Score = 36.2 bits (82), Expect = 0.032
Identities = 31/113 (27%), Positives = 54/113 (47%), Gaps = 37/113 (32%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVD 62
+TE +E+E+ + ++++EA E E + + EER K ++
Sbjct: 545 ETESEEFEKLK------QKQQEAALELEELKKKREERRKV------------------LE 580
Query: 63 FDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQR 115
++ RK+ E D ++ +EEEE LKE IERRR+E AE+++
Sbjct: 581 EEEQRRKQEEAD-------------RKLREEEEKRRLKEEIERRRAEAAEKRQ 620
Score = 34.7 bits (78), Expect = 0.094
Identities = 29/119 (24%), Positives = 55/119 (46%), Gaps = 16/119 (13%)
Query: 87 EQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAED 146
E R+++ EE+ ERI +R++ E++ R + R RQ +L + K+EEE+ + D
Sbjct: 9 ELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQ----KQEEESLGQVTD 64
Query: 147 -----------DAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKKPLD 194
D + K +N G ++ +R+ R+ +++ ER+K D
Sbjct: 65 QVEVNAQNSVPDEEAKTTTTNTQVE-GDDEAAFLERLARREERRQKRLQEALERQKEFD 122
Score = 29.3 bits (64), Expect = 4.0
Identities = 35/163 (21%), Positives = 66/163 (40%), Gaps = 22/163 (13%)
Query: 1 MSDTEEQEYEEEQPEEEA----AEEEEEAPEEP---EPVAEPEEERPKPSRPVVPPL--I 51
++D E + P+EEA + E +E E +A EE R K + +
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEF 121
Query: 52 PPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERA 111
P I + + +RM+ D E +T ++EE+ + +ER E +E
Sbjct: 122 DPTITDASL----SLPSRRMQNDTAENETT---------EKEEKSESRQERYEIEETETV 168
Query: 112 EQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVL 154
+ + + + K +++ +EEEE KR + +V+
Sbjct: 169 TKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVM 211
>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
isoform 3 [Homo sapiens]
Length = 1212
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/196 (25%), Positives = 95/196 (48%), Gaps = 27/196 (13%)
Query: 4 TEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDF 63
T ++ E+++ E E + EEE E PE EP P + R DF
Sbjct: 309 TRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTL------------RRDF 356
Query: 64 DDIHRKRMEK-DLLELQTLIDVHFEQRKKEEEEL--VALKERIERRRSERAEQQRFRTEK 120
+ ++ E+ + L Q L+ EQ+ +E+EE L ER +R ++ +++R ++
Sbjct: 357 LRLQQENKERSEALRRQQLLQ---EQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQ 413
Query: 121 ERERQAKLAEEK-MRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGR 179
RER+A+ +E+ R+ E+E K+R E+ +++K +AE+++ + + +
Sbjct: 414 RREREARRQQEREQRRREQEEKRRLEELERRRKEEEERR--------RAEEEKRRVEREQ 465
Query: 180 EMKVRILSERKKPLDI 195
E R L E ++ L++
Sbjct: 466 EYIRRQLEEEQRHLEV 481
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/196 (25%), Positives = 95/196 (48%), Gaps = 27/196 (13%)
Query: 4 TEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDF 63
T ++ E+++ E E + EEE E PE EP P + R DF
Sbjct: 309 TRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTL------------RRDF 356
Query: 64 DDIHRKRMEK-DLLELQTLIDVHFEQRKKEEEEL--VALKERIERRRSERAEQQRFRTEK 120
+ ++ E+ + L Q L+ EQ+ +E+EE L ER +R ++ +++R ++
Sbjct: 357 LRLQQENKERSEALRRQQLLQ---EQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQ 413
Query: 121 ERERQAKLAEEK-MRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGR 179
RER+A+ +E+ R+ E+E K+R E+ +++K +AE+++ + + +
Sbjct: 414 RREREARRQQEREQRRREQEEKRRLEELERRRKEEEERR--------RAEEEKRRVEREQ 465
Query: 180 EMKVRILSERKKPLDI 195
E R L E ++ L++
Sbjct: 466 EYIRRQLEEEQRHLEV 481
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/196 (25%), Positives = 95/196 (48%), Gaps = 27/196 (13%)
Query: 4 TEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDF 63
T ++ E+++ E E + EEE E PE EP P + R DF
Sbjct: 309 TRKKRGEKDETEYEYSGSEEEEEEVPEQEGEPSSIVNVPGESTL------------RRDF 356
Query: 64 DDIHRKRMEK-DLLELQTLIDVHFEQRKKEEEEL--VALKERIERRRSERAEQQRFRTEK 120
+ ++ E+ + L Q L+ EQ+ +E+EE L ER +R ++ +++R ++
Sbjct: 357 LRLQQENKERSEALRRQQLLQ---EQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQ 413
Query: 121 ERERQAKLAEEK-MRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGR 179
RER+A+ +E+ R+ E+E K+R E+ +++K +AE+++ + + +
Sbjct: 414 RREREARRQQEREQRRREQEEKRRLEELERRRKEEEERR--------RAEEEKRRVEREQ 465
Query: 180 EMKVRILSERKKPLDI 195
E R L E ++ L++
Sbjct: 466 EYIRRQLEEEQRHLEV 481
Score = 32.7 bits (73), Expect = 0.36
Identities = 33/136 (24%), Positives = 61/136 (44%), Gaps = 28/136 (20%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
E Q+ E+Q E+ EE++ E A ++ER + R + E+ +
Sbjct: 394 ERQKRIEQQKEQRRRLEEQQRRERE---ARRQQEREQRRRE-----------QEEKRRLE 439
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKER-- 122
++ R+R E++ E+R+ EEE+ +E+ RR EQ+ +++
Sbjct: 440 ELERRRKEEE------------ERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLL 487
Query: 123 ERQAKLAEEKMRKEEE 138
+ QA L E + R+ EE
Sbjct: 488 QEQAMLLECRWREMEE 503
Score = 28.9 bits (63), Expect = 5.2
Identities = 33/143 (23%), Positives = 59/143 (41%), Gaps = 35/143 (24%)
Query: 6 EQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDD 65
EQ+ E+ + EE E EA + E E+ K ++ E ER ++
Sbjct: 400 EQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKR-----------RLEELERRRKEE 448
Query: 66 IHRKRMEKDLLELQTLIDVHFEQRKKE-EEELVALKERIERRRSERAEQQRFR------- 117
R+R E+ E+R+ E E+E + + E+R E +QQ +
Sbjct: 449 EERRRAEE-------------EKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAMLLE 495
Query: 118 ---TEKERERQAKLAEEKMRKEE 137
E E RQA+ + ++++E+
Sbjct: 496 CRWREMEEHRQAERLQRQLQQEQ 518
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 56.2 bits (134), Expect = 3e-08
Identities = 54/177 (30%), Positives = 80/177 (45%), Gaps = 28/177 (15%)
Query: 4 TEEQEYEEEQPEEEAAEEEEE-----APEEPE-PVAEPEEERPKPSRPVVPPL--IPPKI 55
T E E E PEE++ + PE P A P++ P PL I K
Sbjct: 266 TPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTSPFPTSTPLRRITKKF 325
Query: 56 PEGE------RVDFDD--------IHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKE 101
+G R+ D + +R EK+ L+ + ++KKEEE+ + KE
Sbjct: 326 VKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKE 385
Query: 102 RIERRRS---ERAEQQRFRTEKERERQAKL---AEEKMRKEEEEAKKRAEDDAKKKK 152
R E+R E+AE+QR + E+ +ERQ L EEK +KEEE+ + E K +K
Sbjct: 386 RREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKAEK 442
Score = 39.3 bits (90), Expect = 0.004
Identities = 29/108 (26%), Positives = 58/108 (53%), Gaps = 16/108 (14%)
Query: 10 EEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRK 69
E+E+ +EEA +EEA ++ E E +E+ + R E+ + + ++
Sbjct: 356 EKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKR--------------EKDEKEKAEKQ 401
Query: 70 RMEKDLL-ELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRF 116
R++++ E Q ++ E+++K+EEE L+E +R ++E+AE RF
Sbjct: 402 RLKEERRKERQEALEAKLEEKRKKEEEK-RLREEEKRIKAEKAEITRF 448
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 54.7 bits (130), Expect = 9e-08
Identities = 47/177 (26%), Positives = 77/177 (43%), Gaps = 26/177 (14%)
Query: 15 EEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKD 74
+ E E E E E E E ER K R E E+ + ++ E+
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERR------------EREKRKREREKERKRERG 82
Query: 75 LLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAEEKMR 134
E + +RKKEE E + E + E E+++ + +KER R +K +E+ R
Sbjct: 83 KKEKKG-------ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERER 135
Query: 135 KEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGKRQTGREMKVRILSERKK 191
KEE + ++R E + KK++ K +KR ++Q G + + R ERK+
Sbjct: 136 KEERKREERKERERKKEEREKERER-------KERKKRERKQVGEKEEERKEKERKE 185
Score = 54.3 bits (129), Expect = 1e-07
Identities = 55/191 (28%), Positives = 89/191 (46%), Gaps = 41/191 (21%)
Query: 5 EEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDFD 64
E ++ E E+ + +E +E E+ + + ++ER + S+ EG+ +
Sbjct: 89 ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSK------------EGKERERK 136
Query: 65 DIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKER-E 123
+ RKR E+ E + E+R+KE E KER +R R + E++ R EKER E
Sbjct: 137 E-ERKREERKERERKK------EEREKERER----KERKKRERKQVGEKEEERKEKERKE 185
Query: 124 RQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKAEQKRGK---RQTGRE 180
R+ + K RK+E E K+R E ++KK K E+K+ + RQT
Sbjct: 186 RKKRERNRKERKKERERKERRERKKERKK--------------KEERKKERQKDRQTNWR 231
Query: 181 MKVRILSERKK 191
K R ERK+
Sbjct: 232 EKERGKRERKE 242
Score = 48.9 bits (115), Expect = 5e-06
Identities = 41/149 (27%), Positives = 70/149 (46%), Gaps = 30/149 (20%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVD 62
+ E +E EE++ ++ ++E + E +EER + R
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREER------------------ 144
Query: 63 FDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALK--ERIERRRSERAEQQRFRTE- 119
+ RK+ E++ + ++RKK E + V K ER E+ R ER +++R R E
Sbjct: 145 -KERERKKEEREK-------ERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKER 196
Query: 120 -KERERQAKLAEEKMRKEEEEAKKRAEDD 147
KERER+ + +K RK++EE KK + D
Sbjct: 197 KKERERKERRERKKERKKKEERKKERQKD 225
Score = 46.2 bits (108), Expect = 3e-05
Identities = 38/141 (26%), Positives = 67/141 (47%), Gaps = 29/141 (20%)
Query: 3 DTEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVD 62
+ +E+ EE+ E E +EE E E +ER K R V E ER +
Sbjct: 134 ERKEERKREERKERERKKEEREKERE-------RKERKKRERKQVGE------KEEERKE 180
Query: 63 FDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKER 122
+ RK+ E++ ++RKKE E KER ER++ + +++R + E+++
Sbjct: 181 KERKERKKRERNR-----------KERKKERER----KERRERKKERKKKEER-KKERQK 224
Query: 123 ERQAKLAEEKMRKEEEEAKKR 143
+RQ E++ K E + +K+
Sbjct: 225 DRQTNWREKERGKRERKERKK 245
Score = 45.8 bits (107), Expect = 4e-05
Identities = 40/147 (27%), Positives = 65/147 (44%), Gaps = 27/147 (18%)
Query: 4 TEEQEYEEEQPEEEAAEEEEEAPEEPEPVAEPEEERPKPSRPVVPPLIPPKIPEGERVDF 63
T ++ E E+ EE EE +E + E E E+ER + R K E ++V
Sbjct: 126 TSKEGKERERKEERKREERKERERKKE---EREKERERKER---------KKRERKQVGE 173
Query: 64 DDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERE 123
+ RK E+ ++RKK E K+ ER R ER E+++ R +KE
Sbjct: 174 KEEERKEKER-------------KERKKRERNRKERKK--ERERKERRERKKERKKKEER 218
Query: 124 RQAKLAEEKMRKEEEEAKKRAEDDAKK 150
++ + + + E+E KR + KK
Sbjct: 219 KKERQKDRQTNWREKERGKRERKERKK 245
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.129 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,509,203
Number of Sequences: 37866
Number of extensions: 745135
Number of successful extensions: 36282
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 987
Number of HSP's successfully gapped in prelim test: 1017
Number of HSP's that attempted gapping in prelim test: 10309
Number of HSP's gapped (non-prelim): 12342
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.