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Search of human proteins with 106067657
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|106067657 luteinizing hormone/choriogonadotropin receptor
precursor [Homo sapiens]
(699 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|106067657 luteinizing hormone/choriogonadotropin receptor pre... 1404 0.0
gi|31657138 follicle stimulating hormone receptor isoform 1 prec... 683 0.0
gi|64085121 thyroid stimulating hormone receptor isoform 1 precu... 682 0.0
gi|31657136 follicle stimulating hormone receptor isoform 2 prec... 566 e-161
gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 198 2e-50
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 198 2e-50
gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo... 169 6e-42
gi|217330610 thyroid stimulating hormone receptor isoform 3 prec... 166 9e-41
gi|64085161 thyroid stimulating hormone receptor isoform 2 precu... 166 9e-41
gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo... 153 6e-37
gi|62912474 leucine-rich repeat-containing G protein-coupled rec... 149 9e-36
gi|62912472 leucine-rich repeat-containing G protein-coupled rec... 147 3e-35
gi|62912470 leucine-rich repeat-containing G protein-coupled rec... 147 3e-35
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 80 8e-15
gi|4557859 somatostatin receptor 2 [Homo sapiens] 77 5e-14
gi|32307152 oxytocin receptor [Homo sapiens] 72 2e-12
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 70 9e-12
gi|149944554 somatostatin receptor 4 [Homo sapiens] 69 1e-11
gi|4557857 somatostatin receptor 1 [Homo sapiens] 69 2e-11
gi|71999131 opsin 3 [Homo sapiens] 67 6e-11
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 67 7e-11
gi|148228829 G protein-coupled receptor 1 [Homo sapiens] 67 7e-11
gi|36951012 G protein-coupled receptor 1 [Homo sapiens] 67 7e-11
gi|4557865 somatostatin receptor 5 [Homo sapiens] 66 1e-10
gi|161484640 neuromedin B receptor [Homo sapiens] 65 2e-10
gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo sap... 65 2e-10
gi|50233854 olfactory receptor, family 14, subfamily A, member 1... 65 2e-10
gi|71999143 opsin 4 isoform 2 [Homo sapiens] 65 3e-10
gi|52317239 olfactory receptor, family 4, subfamily D, member 10... 64 4e-10
gi|157426873 tachykinin receptor 2 [Homo sapiens] 62 1e-09
>gi|106067657 luteinizing hormone/choriogonadotropin receptor
precursor [Homo sapiens]
Length = 699
Score = 1404 bits (3634), Expect = 0.0
Identities = 699/699 (100%), Positives = 699/699 (100%)
Query: 1 MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLP 60
MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLP
Sbjct: 1 MKQRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLP 60
Query: 61 VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI 120
VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI
Sbjct: 61 VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI 120
Query: 121 NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK 180
NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK
Sbjct: 121 NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK 180
Query: 181 LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY 240
LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY
Sbjct: 181 LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY 240
Query: 241 GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF 300
GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF
Sbjct: 241 GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF 300
Query: 301 SKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD 360
SKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD
Sbjct: 301 SKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYD 360
Query: 361 FLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDS 420
FLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDS
Sbjct: 361 FLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDS 420
Query: 421 QTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRL 480
QTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRL
Sbjct: 421 QTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRL 480
Query: 481 RHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFF 540
RHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFF
Sbjct: 481 RHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFF 540
Query: 541 IICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLIT 600
IICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLIT
Sbjct: 541 IICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLIT 600
Query: 601 VTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYT 660
VTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYT
Sbjct: 601 VTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYT 660
Query: 661 SNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC 699
SNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC
Sbjct: 661 SNCKNGFTGSNKPSQSTLKLSTLHCQGTALLDKTRYTEC 699
>gi|31657138 follicle stimulating hormone receptor isoform 1
precursor [Homo sapiens]
Length = 695
Score = 683 bits (1763), Expect = 0.0
Identities = 348/620 (56%), Positives = 459/620 (74%), Gaps = 13/620 (2%)
Query: 61 VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI 120
++VI AF G ++ KIEISQ D LE IEA+ F NL L EI I+ NL YI P AF
Sbjct: 58 LRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQ 117
Query: 121 NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK 180
NLP L+YL I NTGI+ PDV K+ S + +L+I DN++I TI N+F G++ ESV L
Sbjct: 118 NLPNLQYLLISNTGIKHLPDVHKIHSLQK-VLLDIQDNINIHTIERNSFVGLSFESVILW 176
Query: 181 LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY 240
L NG +E+ + AFNGT L L L +N +LE++ N F GA+GP LDIS T++ +LPSY
Sbjct: 177 LNKNGIQEIHNCAFNGTQLDELNLSDNNNLEELPNDVFHGASGPVILDISRTRIHSLPSY 236
Query: 241 GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF 300
GLE++++L A S+Y+LKKLP+ E V L+EA+LTYPSHCCAF N + +++
Sbjct: 237 GLENLKKLRARSTYNLKKLPTLEKLVALMEASLTYPSHCCAFANWRRQISELHPICNKSI 296
Query: 301 SKQCESTVRKVNNKTLYSSMLAESELS---GWD-----YEYGFCLPKTP-RCAPEPDAFN 351
+Q + + + SS+ ++E S G+D ++Y C C+P+PDAFN
Sbjct: 297 LRQEVDYMTQARGQR--SSLAEDNESSYSRGFDMTYTEFDYDLCNEVVDVTCSPKPDAFN 354
Query: 352 PCEDIMGYDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLY 411
PCEDIMGY+ LRVLIW I+ILAI GN+ VL +L TS+YKLTVPRFLMCNL+FAD C+G+Y
Sbjct: 355 PCEDIMGYNILRVLIWFISILAITGNIIVLVILTTSQYKLTVPRFLMCNLAFADLCIGIY 414
Query: 412 LLLIASVDSQTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYA 471
LLLIASVD TK QY+N+AIDWQTG+GC AGFFTVFASELSVYTLT ITLERWHTIT+A
Sbjct: 415 LLLIASVDIHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHA 474
Query: 472 IHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTI 531
+ LD K++LRHA +M+ GW+F+ A+ P+ G+S+YMKVSIC PMD+++ LSQ+Y++++
Sbjct: 475 MQLDCKVQLRHAASVMVMGWIFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSL 534
Query: 532 LILNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAIS 591
L+LNV+AF +IC CYI IY VRNP +++++ DT+IAK+MA+LIFTDF CMAPISFFAIS
Sbjct: 535 LVLNVLAFVVICGCYIHIYLTVRNPNIVSSSSDTRIAKRMAMLIFTDFLCMAPISFFAIS 594
Query: 592 AAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELY 651
A+ KVPLITV+ +K+LLVLF+PINSCANPFLYAIFTK F+RDFF+LLSK GC + +A++Y
Sbjct: 595 ASLKVPLITVSKAKILLVLFHPINSCANPFLYAIFTKNFRRDFFILLSKCGCYEMQAQIY 654
Query: 652 RRKDFS-AYTSNCKNGFTGS 670
R + S + ++ +NG S
Sbjct: 655 RTETSSTVHNTHPRNGHCSS 674
>gi|64085121 thyroid stimulating hormone receptor isoform 1
precursor [Homo sapiens]
Length = 764
Score = 682 bits (1760), Expect = 0.0
Identities = 364/704 (51%), Positives = 470/704 (66%), Gaps = 63/704 (8%)
Query: 10 LLKLLLLLQPPLPRALREALCPEP-CNCVPDGALRC--------PGPTAGLTRLSLAYLP 60
LL+L+LLL LPR L C P C C + R P L L
Sbjct: 6 LLQLVLLLD--LPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETH 63
Query: 61 VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI 120
++ IPS AF L + +I +S +L+++E+++F NL ++ I I+NT+NL YI+P A
Sbjct: 64 LRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALK 123
Query: 121 NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK 180
LP LK+L I NTG++ FPD+TKV+S++ FILEI DN ++T+IP NAFQG+ NE++TLK
Sbjct: 124 ELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLK 183
Query: 181 LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGA-TGPKTLDISSTKLQALPS 239
LY NGF VQ +AFNGT L ++ L +N +L + AF G +GP LD+S T + ALPS
Sbjct: 184 LYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLLDVSQTSVTALPS 243
Query: 240 YGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRN----------LPTKE 289
GLE ++ LIA ++++LKKLP +F++L A L+YPSHCCAF+N L E
Sbjct: 244 KGLEHLKELIARNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLMCNE 303
Query: 290 --------------------QNFSHSISENFSKQCE-STVRKVNNKTLYSSMLAESE--- 325
Q + ++ ++ E S + +N Y E E
Sbjct: 304 SSMQSLRQRKSVNALNSPLHQEYEENLGDSIVGYKEKSKFQDTHNNAHYYVFFEEQEDEI 363
Query: 326 --------------LSGWD--YEYGFCLPKTPR-CAPEPDAFNPCEDIMGYDFLRVLIWL 368
L +D Y+Y C C P+ D FNPCEDIMGY FLR+++W
Sbjct: 364 IGFGQELKNPQEETLQAFDSHYDYTICGDSEDMVCTPKSDEFNPCEDIMGYKFLRIVVWF 423
Query: 369 INILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYN 428
+++LA++GN+ VL +LLTS YKL VPRFLMCNL+FADFCMG+YLLLIASVD T +YYN
Sbjct: 424 VSLLALLGNVFVLLILLTSHYKLNVPRFLMCNLAFADFCMGMYLLLIASVDLYTHSEYYN 483
Query: 429 HAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIML 488
HAIDWQTG GC+TAGFFTVFASELSVYTLTVITLERW+ IT+A+ LD+K+RLRHA IM+
Sbjct: 484 HAIDWQTGPGCNTAGFFTVFASELSVYTLTVITLERWYAITFAMRLDRKIRLRHACAIMV 543
Query: 489 GGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFFIICACYIK 548
GGW+ L+A+LPLVG+S+Y KVSIC PMD ET L+ YI+ +L LN+VAF I+C CY+K
Sbjct: 544 GGWVCCFLLALLPLVGISSYAKVSICLPMDTETPLALAYIVFVLTLNIVAFVIVCCCYVK 603
Query: 549 IYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLL 608
IY VRNP+ +KDTKIAK+MA+LIFTDF CMAPISF+A+SA PLITV+NSK+LL
Sbjct: 604 IYITVRNPQYNPGDKDTKIAKRMAVLIFTDFICMAPISFYALSAILNKPLITVSNSKILL 663
Query: 609 VLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYR 652
VLFYP+NSCANPFLYAIFTK FQRD F+LLSKFG CKR+A+ YR
Sbjct: 664 VLFYPLNSCANPFLYAIFTKAFQRDVFILLSKFGICKRQAQAYR 707
>gi|31657136 follicle stimulating hormone receptor isoform 2
precursor [Homo sapiens]
Length = 633
Score = 566 bits (1458), Expect = e-161
Identities = 304/612 (49%), Positives = 407/612 (66%), Gaps = 59/612 (9%)
Query: 61 VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI 120
++VI AF G ++ KIEISQ D LE IEA+ F NL L EI I+ NL YI P AF
Sbjct: 58 LRVIQKGAFSGFGDLEKIEISQNDVLEVIEADVFSNLPKLHEIRIEKANNLLYINPEAFQ 117
Query: 121 NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK 180
NLP L+YL I NTGI+ PDV K+ S + +L+I DN++I TI N+F G++ ESV L
Sbjct: 118 NLPNLQYLLISNTGIKHLPDVHKIHSLQK-VLLDIQDNINIHTIERNSFVGLSFESVILW 176
Query: 181 LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY 240
L NG +E+ HN AF G
Sbjct: 177 LNKNGIQEI------------------------HNCAFNGT------------------- 193
Query: 241 GLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENF 300
+ L + + +L++LP+ + F + H +++ +E ++
Sbjct: 194 ---QLDELNLSDNNNLEELPN-DVFHGASGPVILSELHPICNKSILRQEVDYMTQARGQR 249
Query: 301 SKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTP-RCAPEPDAFNPCEDIMGY 359
S E +N++ YS +++ +++Y C C+P+PDAFNPCEDIMGY
Sbjct: 250 SSLAE------DNESSYSRGF---DMTYTEFDYDLCNEVVDVTCSPKPDAFNPCEDIMGY 300
Query: 360 DFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVD 419
+ LRVLIW I+ILAI GN+ VL +L TS+YKLTVPRFLMCNL+FAD C+G+YLLLIASVD
Sbjct: 301 NILRVLIWFISILAITGNIIVLVILTTSQYKLTVPRFLMCNLAFADLCIGIYLLLIASVD 360
Query: 420 SQTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLR 479
TK QY+N+AIDWQTG+GC AGFFTVFASELSVYTLT ITLERWHTIT+A+ LD K++
Sbjct: 361 IHTKSQYHNYAIDWQTGAGCDAAGFFTVFASELSVYTLTAITLERWHTITHAMQLDCKVQ 420
Query: 480 LRHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAF 539
LRHA +M+ GW+F+ A+ P+ G+S+YMKVSIC PMD+++ LSQ+Y++++L+LNV+AF
Sbjct: 421 LRHAASVMVMGWIFAFAAALFPIFGISSYMKVSICLPMDIDSPLSQLYVMSLLVLNVLAF 480
Query: 540 FIICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLI 599
+IC CYI IY VRNP +++++ DT+IAK+MA+LIFTDF CMAPISFFAISA+ KVPLI
Sbjct: 481 VVICGCYIHIYLTVRNPNIVSSSSDTRIAKRMAMLIFTDFLCMAPISFFAISASLKVPLI 540
Query: 600 TVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFS-A 658
TV+ +K+LLVLF+PINSCANPFLYAIFTK F+RDFF+LLSK GC + +A++YR + S
Sbjct: 541 TVSKAKILLVLFHPINSCANPFLYAIFTKNFRRDFFILLSKCGCYEMQAQIYRTETSSTV 600
Query: 659 YTSNCKNGFTGS 670
+ ++ +NG S
Sbjct: 601 HNTHPRNGHCSS 612
>gi|4504379 leucine-rich repeat-containing G protein-coupled
receptor 5 [Homo sapiens]
Length = 907
Score = 198 bits (503), Expect = 2e-50
Identities = 162/618 (26%), Positives = 285/618 (46%), Gaps = 34/618 (5%)
Query: 43 RCPGPTAGLTRLSLAYLPVKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSE 102
+C L L L Y + P+ A R L+ + ++ +++ I AF N S
Sbjct: 228 KCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELGFHS-NNIRSIPEKAFVG--NPSL 283
Query: 103 ILIQNTKN-LRYIEPGAFINLPRLKYLSICNTG-IRKFPDVTKVFSSESNFIL------- 153
I I N ++++ AF +LP L+ L++ I +FPD+T + ES +
Sbjct: 284 ITIHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGTANLESLTLTGAQISSL 343
Query: 154 --EICD---NLHITTIPGNAFQGMNNESVTLKLYG-----NGFEEVQSHAFNGT-TLTSL 202
+C+ NL + + N + + + SV KL N E++ F +L SL
Sbjct: 344 PQTVCNQLPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSL 403
Query: 203 ELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSR 262
L N + +H AF LD+SS L + P GL + L T +++L+ L S
Sbjct: 404 NLAWN-KIAIIHPNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKLTGNHALQSLISS 462
Query: 263 ETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENFSKQCESTVRKVNNKTLYSSMLA 322
E F L + Y CCAF ++ IS ++K S++ ++ K
Sbjct: 463 ENFPELKVIEMPYAYQCCAFGVCEN-----AYKISNQWNKGDNSSMDDLHKKDAGMFQAQ 517
Query: 323 -ESELSGW--DYEYGFCLPKTPRCAPEPDAFNPCEDIMGYDFLRVLIWLINILAIMGNMT 379
E +L + D+E + +C+P P F PCE ++ +R+ +W I +LA+ N
Sbjct: 518 DERDLEDFLLDFEEDLKALHSVQCSPSPGPFKPCEHLLDGWLIRIGVWTIAVLALTCNAL 577
Query: 380 VLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGC 439
V + S ++ + L+ ++ + G+ ++A VD+ T G + H W+ G GC
Sbjct: 578 VTSTVFRSPLYISPIKLLIGVIAAVNMLTGVSSAVLAGVDAFTFGSFARHGAWWENGVGC 637
Query: 440 STAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAM 499
GF ++FASE SV+ LT+ LER ++ Y+ + K +I+L L + +A
Sbjct: 638 HVIGFLSIFASESSVFLLTLAALERGFSVKYSAKFETKAPFSSLKVIILLCALLALTMAA 697
Query: 500 LPLVGVSNYMKVSICFPMDVETTLSQVYILTILILNVVAFFIICACYIKIYFAVRNPELM 559
+PL+G S Y +C P+ + Y++ +++LN + F ++ Y K+Y + +L
Sbjct: 698 VPLLGGSKYGASPLCLPLPFGEPSTMGYMVALILLNSLCFLMMTIAYTKLYCNLDKGDL- 756
Query: 560 ATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPINSCAN 619
D + K +A+L+FT+ P++F + S+ + I+ K +L++ P+ +C N
Sbjct: 757 ENIWDCSMVKHIALLLFTNCILNCPVAFLSFSSLINLTFISPEVIKFILLVVVPLPACLN 816
Query: 620 PFLYAIFTKTFQRDFFLL 637
P LY +F F+ D L
Sbjct: 817 PLLYILFNPHFKEDLVSL 834
Score = 50.8 bits (120), Expect = 4e-06
Identities = 61/252 (24%), Positives = 110/252 (43%), Gaps = 29/252 (11%)
Query: 30 CPEPCNCVPDGALRCPGPTAGLTRLSLAYLP--VKVIPSQAFRGLNEVIKIEISQIDSLE 87
CP C+C PDG + + L L+ LP + V S +N + ++ + + SL
Sbjct: 34 CPTHCHCEPDGRMLL---RVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLR 90
Query: 88 RIE-------------ANAFDNLLNLSEILIQNTKNLRYIEPGAFINLPRLKYLSICNTG 134
+E AF L +L +++QN + LR++ A NL L+ L +
Sbjct: 91 FLEELRLAGNALTYIPKGAFTGLYSLKVLMLQNNQ-LRHVPTEALQNLRSLQSLRLDANH 149
Query: 135 IRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNN-ESVTLKLYGNGFEEVQSHA 193
I P FS + D+ +T IP AF+ ++ +++TL L N + +A
Sbjct: 150 ISYVP--PSCFSGLHSLRHLWLDDNALTEIPVQAFRSLSALQAMTLAL--NKIHHIPDYA 205
Query: 194 F-NGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRL--IA 250
F N ++L L L N + + F G +TLD++ L P+ + ++ L +
Sbjct: 206 FGNLSSLVVLHLHNN-RIHSLGKKCFDGLHSLETLDLNYNNLDEFPT-AIRTLSNLKELG 263
Query: 251 TSSYSLKKLPSR 262
S +++ +P +
Sbjct: 264 FHSNNIRSIPEK 275
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 198 bits (503), Expect = 2e-50
Identities = 149/588 (25%), Positives = 274/588 (46%), Gaps = 43/588 (7%)
Query: 61 VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI 120
+ VIP AF G N +++ + L + +AF NL +L ++I+ ++ F
Sbjct: 260 ISVIPDGAFDG-NPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQ-----FP 313
Query: 121 NLPRLKYLSICNTGIRKFPDVTKVFSSESNFI--LEICDNLHITTIPGNAFQGMNNESVT 178
NL +L K + E + L++ N +I +P +F G +
Sbjct: 314 NLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYN-NIRDLP--SFNGCHALE-E 369
Query: 179 LKLYGNGFEEVQSHAFNGT-TLTSLELKENVHLEKMHNGAFRGATGPKT-LDISSTKLQA 236
+ L N +++ F G +L L+L N+ + ++H+ AF GP T LD+S +L +
Sbjct: 370 ISLQRNQIYQIKEGTFQGLISLRILDLSRNL-IHEIHSRAF-ATLGPITNLDVSFNELTS 427
Query: 237 LPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAF------RNLPTKEQ 290
P+ GL + +L ++ LK+ + + FVNL ++ Y CCAF NL T++
Sbjct: 428 FPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYAYQCCAFWGCDSYANLNTEDN 487
Query: 291 NFS-HSISENFSKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRCAPEPDA 349
+ HS+++ + V +S ++ C P A
Sbjct: 488 SLQDHSVAQEKGTADAANVTSTLENEEHSQIIIH-------------------CTPSTGA 528
Query: 350 FNPCEDIMGYDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMG 409
F PCE ++G +R+ +W I ++A+ N+ V+ S L + + +S ++ MG
Sbjct: 529 FKPCEYLLGSWMIRLTVWFIFLVALFFNLLVILTTFASCTSLPSSKLFIGLISVSNLFMG 588
Query: 410 LYLLLIASVDSQTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTIT 469
+Y ++ +D+ + G++ I W+TGSGC AGF VF+SE +++ L + T+ER +
Sbjct: 589 IYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGFLAVFSSESAIFLLMLATVERSLSAK 648
Query: 470 YAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDVETTLSQVYIL 529
+ + L+ + L +L +++ PL Y +C P T S + +
Sbjct: 649 DIMKNGKSNHLKQFRVAALLAFLGATVAGCFPLFHRGEYSASPLCLPFPTGETPSLGFTV 708
Query: 530 TILILNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFA 589
T+++LN +AF ++ Y K+Y + +L + N + + K +A LIFT+ P++FF+
Sbjct: 709 TLVLLNSLAFLLMAVIYTKLYCNLEKEDL-SENSQSSMIKHVAWLIFTNCIFFCPVAFFS 767
Query: 590 ISAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLL 637
+ I+ K + ++F+P+ +C NP LY F F+ D+ LL
Sbjct: 768 FAPLITAISISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKEDWKLL 815
Score = 54.7 bits (130), Expect = 3e-07
Identities = 62/251 (24%), Positives = 111/251 (44%), Gaps = 33/251 (13%)
Query: 22 PRALREALCPEPCNCVPDGALRCPGPTAGLTRLSLAYLPVKVIPSQAFRGLNEVIKIEIS 81
P LC PC+C D + C G GLT + GL+ +
Sbjct: 21 PSGAAPPLCAAPCSCDGDRRVDCSG--KGLTAVP--------------EGLSAFTQALDI 64
Query: 82 QIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFP-D 140
++++ ++ +AF N L E+ + +L +I P A L LK L++ N ++ P +
Sbjct: 65 SMNNITQLPEDAFKNFPFLEELQLAG-NDLSFIHPKALSGLKELKVLTLQNNQLKTVPSE 123
Query: 141 VTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAF-NGTTL 199
+ S+ + L D HIT++P ++F+G+ + L L N EV H N TL
Sbjct: 124 AIRGLSALQSLRL---DANHITSVPEDSFEGL-VQLRHLWLDDNSLTEVPVHPLSNLPTL 179
Query: 200 TSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSY---GLESIQRL------IA 250
+L L N + + + AF + L + + K+++L + GL++++ L +
Sbjct: 180 QALTLALN-KISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLG 238
Query: 251 TSSYSLKKLPS 261
++K LPS
Sbjct: 239 EFPQAIKALPS 249
>gi|85986601 relaxin/insulin-like family peptide receptor 1 [Homo
sapiens]
Length = 757
Score = 169 bits (429), Expect = 6e-42
Identities = 140/603 (23%), Positives = 277/603 (45%), Gaps = 51/603 (8%)
Query: 45 PGPTAGLTRLSLAYLPVKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEIL 104
P ++ +T +SL + ++ +P F+ +++ K+ + Q + + I AF L +L+++
Sbjct: 122 PSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYL-QNNKITSISIYAFRGLNSLTKLY 180
Query: 105 IQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTI 164
+ + + + +++PG F +L RL++L I + + + T F ++ IL + N +T +
Sbjct: 181 LSHNR-ITFLKPGVFEDLHRLEWLIIEDNHLSRISPPT--FYGLNSLILLVLMNNVLTRL 237
Query: 165 PGNAFQGMNNESVTLKLYGNGFEEVQSHAF-NGTTLTSLELKENVHLEKMHNGAFRGATG 223
P L L GN +++ F + + LT L +++N + ++ F
Sbjct: 238 PDKPLCQHMPRLHWLDLEGNHIHNLRNLTFISCSNLTVLVMRKN-KINHLNENTFAPLQK 296
Query: 224 PKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCCAFR 283
LD+ S K++ LP + ++ L S +L P ++ N + + S
Sbjct: 297 LDELDLGSNKIENLPPLIFKDLKEL---SQLNLSYNPIQKIQANQFDYLVKLKSLSLEGI 353
Query: 284 NLPTKEQNFSHSISENFSKQCESTVRKVNNKTLYSSMLAESELSGWDYEYGFCLPKTPRC 343
+ +Q ++ ++ S + ++Y P C
Sbjct: 354 EISNIQQR------------------------MFRPLMNLSHIYFKKFQYCGYAPHVRSC 389
Query: 344 APEPDAFNPCEDIMGYDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSF 403
P D + E+++ RV +W+++ + GN+ V+ + R + + + +L
Sbjct: 390 KPNTDGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRSENKLYAMSIISLCC 449
Query: 404 ADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLE 463
AD MG+YL +I D + +G+Y HA W + C G + ++E+SV LT +TLE
Sbjct: 450 ADCLMGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLE 509
Query: 464 RWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVG---VSNYMKVS-ICFPM-- 517
++ I Y + + R I +++ W+ ++A +PL NY + +CFP+
Sbjct: 510 KYICIVYPFRCVRPGKCR-TITVLILIWITGFIVAFIPLSNKEFFKNYYGTNGVCFPLHS 568
Query: 518 -DVETTLSQVYILTILI-LNVVAFFIICACYIKIYFAVRNPELMAT------NKDTKIAK 569
D E+ +Q+Y + I + +N+ AF II Y ++++V + AT K+ +AK
Sbjct: 569 EDTESIGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAK 628
Query: 570 KMAILIFTDFTCMAPISFFAISAAFKVPLI-TVTNSKVLLVLFYPINSCANPFLYAIFTK 628
+ ++FTD C PI + +V + T+T+ V+ +L PINS NP LY + T+
Sbjct: 629 RFFFIVFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFIL--PINSALNPILYTLTTR 686
Query: 629 TFQ 631
F+
Sbjct: 687 PFK 689
>gi|217330610 thyroid stimulating hormone receptor isoform 3
precursor [Homo sapiens]
Length = 274
Score = 166 bits (419), Expect = 9e-41
Identities = 99/228 (43%), Positives = 139/228 (60%), Gaps = 12/228 (5%)
Query: 10 LLKLLLLLQPPLPRALREALCPEP-CNCVPDGALRC--------PGPTAGLTRLSLAYLP 60
LL+L+LLL LPR L C P C C + R P L L
Sbjct: 6 LLQLVLLLD--LPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETH 63
Query: 61 VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI 120
++ IPS AF L + +I +S +L+++E+++F NL ++ I I+NT+NL YI+P A
Sbjct: 64 LRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALK 123
Query: 121 NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK 180
LP LK+L I NTG++ FPD+TKV+S++ FILEI DN ++T+IP NAFQG+ NE++TLK
Sbjct: 124 ELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLK 183
Query: 181 LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGA-TGPKTL 227
LY NGF VQ +AFNGT L ++ L +N +L + AF G +GP L
Sbjct: 184 LYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLL 231
>gi|64085161 thyroid stimulating hormone receptor isoform 2
precursor [Homo sapiens]
Length = 253
Score = 166 bits (419), Expect = 9e-41
Identities = 99/228 (43%), Positives = 139/228 (60%), Gaps = 12/228 (5%)
Query: 10 LLKLLLLLQPPLPRALREALCPEP-CNCVPDGALRC--------PGPTAGLTRLSLAYLP 60
LL+L+LLL LPR L C P C C + R P L L
Sbjct: 6 LLQLVLLLD--LPRDLGGMGCSSPPCECHQEEDFRVTCKDIQRIPSLPPSTQTLKLIETH 63
Query: 61 VKVIPSQAFRGLNEVIKIEISQIDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFI 120
++ IPS AF L + +I +S +L+++E+++F NL ++ I I+NT+NL YI+P A
Sbjct: 64 LRTIPSHAFSNLPNISRIYVSIDVTLQQLESHSFYNLSKVTHIEIRNTRNLTYIDPDALK 123
Query: 121 NLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNNESVTLK 180
LP LK+L I NTG++ FPD+TKV+S++ FILEI DN ++T+IP NAFQG+ NE++TLK
Sbjct: 124 ELPLLKFLGIFNTGLKMFPDLTKVYSTDIFFILEITDNPYMTSIPVNAFQGLCNETLTLK 183
Query: 181 LYGNGFEEVQSHAFNGTTLTSLELKENVHLEKMHNGAFRGA-TGPKTL 227
LY NGF VQ +AFNGT L ++ L +N +L + AF G +GP L
Sbjct: 184 LYNNGFTSVQGYAFNGTKLDAVYLNKNKYLTVIDKDAFGGVYSGPSLL 231
>gi|18677729 relaxin/insulin-like family peptide receptor 2 [Homo
sapiens]
Length = 754
Score = 153 bits (386), Expect = 6e-37
Identities = 161/655 (24%), Positives = 285/655 (43%), Gaps = 65/655 (9%)
Query: 31 PEPCNCVPDGALRC--------PGPTAGLTRLSLAYLPVKVIPSQAFRGLNEVIKIEISQ 82
P+ C+C + L C P + +T LSL + +P + F ++ KI + Q
Sbjct: 112 PQCCDC-KETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFL-Q 169
Query: 83 IDSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFPDVT 142
+ + I AF L NL +IL N + + PG F +L +L +L + + I +
Sbjct: 170 HNCIRHISRKAFFGLCNL-QILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQ-- 226
Query: 143 KVFSS-ESNFILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAF-NGTTLT 200
++F+ S F L + +N ++ +P M + + L GN + + + F + +LT
Sbjct: 227 RLFTGLNSLFFLSMVNN-YLEALPKQMCAQMPQLN-WVDLEGNRIKYLTNSTFLSCDSLT 284
Query: 201 SLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLP 260
L L N + + F LD+SS + L + + ++ L +KL
Sbjct: 285 VLFLPRN-QIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLL--------QKL- 334
Query: 261 SRETFVNLLEATLTYPSHCCAFRNLPTKEQNFSHSISENFSKQCESTVRKVNNKTLYSSM 320
NL L Y +N S+ + S E N ++ M
Sbjct: 335 ------NLSSNPLMY------------LHKNQFESLKQLQSLDLERIEIPNINTRMFQPM 376
Query: 321 LAESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYDFLRVLIWLINILAIMGNMTV 380
S + ++ Y P C P D + ED++ + LR+ +W+I + GN+ V
Sbjct: 377 KNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRIFVWVIAFITCFGNLFV 436
Query: 381 LFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCS 440
+ + + + T + L AD MG+YL + D + +GQY +A+ W C
Sbjct: 437 IGMRSFIKAENTTHAMSIKILCCADCLMGVYLFFVGIFDIKYRGQYQKYALLWMESVQCR 496
Query: 441 TAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAML 500
GF + ++E+SV LT +TLE++ I + + + R +I++ W+ LIA++
Sbjct: 497 LMGFLAMLSTEVSVLLLTYLTLEKFLVIVFPFS-NIRPGKRQTSVILICIWMAGFLIAVI 555
Query: 501 PLVGV----SNYMKVSICFPM---DVETTLSQVYILTILI-LNVVAFFIICACYIKIYFA 552
P + Y K +CFP+ E S+ Y L I + +N++AF II YI ++ +
Sbjct: 556 PFWNKDYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLLAFLIIVFSYITMFCS 615
Query: 553 VRNPELMAT------NKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKV 606
++ L T ++ +A + ++F+D C P+ I + F+V I T +
Sbjct: 616 IQKTALQTTEVRNCFGREVAVANRFFFIVFSDAICWIPVFVVKILSLFRVE-IPDTMTSW 674
Query: 607 LLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYTS 661
+++ F P+NS NP LY + T F+ LL K +R +++ K S TS
Sbjct: 675 IVIFFLPVNSALNPILYTLTTNFFKDKLKQLLHK----HQRKSIFKIKKKSLSTS 725
>gi|62912474 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 3 [Homo sapiens]
Length = 828
Score = 149 bits (376), Expect = 9e-36
Identities = 162/683 (23%), Positives = 276/683 (40%), Gaps = 83/683 (12%)
Query: 3 QRFSALQLLKLLLLLQPPLPRALREALCPEPCNCVPD----------GALRCPGPTAGLT 52
Q FS L LK+L+L L EAL P D A+R G L
Sbjct: 65 QAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLDLNYNKLQEFPVAIRTLGR---LQ 121
Query: 53 RLSLAYLPVKVIPSQAFRGL----------NEVIKIEISQIDSLERIEANAFDNLLNLSE 102
L +K IP +AF G N + + S L ++ + + +++ E
Sbjct: 122 ELGFHNNNIKAIPEKAFMGNPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQE 181
Query: 103 -----------ILIQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVFSSESNF 151
IL +R + G LPRL+ L + + I + P + +
Sbjct: 182 FPDLKGTTSLEILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHR-------- 233
Query: 152 ILEICDNLHITTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNG-TTLTSLELKENVHL 210
C L + L N E+ + F+ ++L +L+L N +
Sbjct: 234 ----CQKLE-----------------EIGLQHNRIWEIGADTFSQLSSLQALDLSWNA-I 271
Query: 211 EKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSRETFVNLLE 270
+H AF LD++ +L LP GL + L + +L + S+++F L
Sbjct: 272 RSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRI 331
Query: 271 ATLTYPSHCCA-------FRNLPTKEQNFSHSISENFSKQCESTV-RKVNNKTLYSSMLA 322
+ Y CC F+ E H E SK+ + R+ N Y L
Sbjct: 332 LEVPYAYQCCPYGMCASFFKASGQWEAEDLHLDDEESSKRPLGLLARQAENH--YDQDLD 389
Query: 323 ESELSGWDYEYGFCLPKTPRCAPEPDAFNPCEDIMGYDFLRVLIWLINILAIMGN-MTVL 381
E +L D + + +C+P P F PCE + +R+ +W I +L+++ N + +L
Sbjct: 390 ELQLEMEDSKPH----PSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLL 445
Query: 382 FVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCST 441
V L +F++ ++ A+ G+ L+ASVD+ T GQ+ + W+TG GC
Sbjct: 446 TVFAGGPVPLPPVKFVVGAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRA 505
Query: 442 AGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAMLP 501
GF V SE SV LT+ ++ +++ + L +LG + L A LP
Sbjct: 506 TGFLAVLGSEASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVLGCLALAGLAAALP 565
Query: 502 LVGVSNYMKVSICFPM--DVETTLSQVYILTILILNVVAFFIICACYIKIYFAVRNPELM 559
L V Y +C P + + + ++++N F ++ YIK+Y + +
Sbjct: 566 LASVGEYGASPLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFE 625
Query: 560 ATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPINSCAN 619
A D + + +A LIF D P++F + ++ + +T K +L++ P+ +C N
Sbjct: 626 AV-WDCAMVRHVAWLIFADGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLN 684
Query: 620 PFLYAIFTKTFQRDFFLLLSKFG 642
P LY +F F+ D L + G
Sbjct: 685 PLLYLLFNPHFRDDLRRLRPRAG 707
>gi|62912472 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 2 [Homo sapiens]
Length = 915
Score = 147 bits (371), Expect = 3e-35
Identities = 134/553 (24%), Positives = 234/553 (42%), Gaps = 49/553 (8%)
Query: 102 EILIQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHI 161
EIL +R + G LPRL+ L + + I + P + + C L
Sbjct: 279 EILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHR------------CQKLE- 325
Query: 162 TTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNG-TTLTSLELKENVHLEKMHNGAFRG 220
+ L N E+ + F+ ++L +L+L N + +H AF
Sbjct: 326 ----------------EIGLQHNRIWEIGADTFSQLSSLQALDLSWNA-IRSIHPEAFST 368
Query: 221 ATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCC 280
LD++ +L LP GL + L + +L + S+++F L + Y CC
Sbjct: 369 LHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCC 428
Query: 281 A-------FRNLPTKEQNFSHSISENFSKQCESTV-RKVNNKTLYSSMLAESELSGWDYE 332
F+ E H E SK+ + R+ N Y L E +L D +
Sbjct: 429 PYGMCASFFKASGQWEAEDLHLDDEESSKRPLGLLARQAENH--YDQDLDELQLEMEDSK 486
Query: 333 YGFCLPKTPRCAPEPDAFNPCEDIMGYDFLRVLIWLINILAIMGN-MTVLFVLLTSRYKL 391
+ +C+P P F PCE + +R+ +W I +L+++ N + +L V L
Sbjct: 487 PH----PSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPL 542
Query: 392 TVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCSTAGFFTVFASE 451
+F++ ++ A+ G+ L+ASVD+ T GQ+ + W+TG GC GF V SE
Sbjct: 543 PPVKFVVGAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSE 602
Query: 452 LSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKV 511
SV LT+ ++ +++ + L +LG + L A LPL V Y
Sbjct: 603 ASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVLGCLALAGLAAALPLASVGEYGAS 662
Query: 512 SICFPM--DVETTLSQVYILTILILNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAK 569
+C P + + + ++++N F ++ YIK+Y + + A D + +
Sbjct: 663 PLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAV-WDCAMVR 721
Query: 570 KMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKT 629
+A LIF D P++F + ++ + +T K +L++ P+ +C NP LY +F
Sbjct: 722 HVAWLIFADGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPH 781
Query: 630 FQRDFFLLLSKFG 642
F+ D L + G
Sbjct: 782 FRDDLRRLRPRAG 794
Score = 46.6 bits (109), Expect = 8e-05
Identities = 69/291 (23%), Positives = 120/291 (41%), Gaps = 33/291 (11%)
Query: 3 QRFSALQLLKLLLLLQPPLPRALREALCPEP-----------CNCVPDGALRCPGPTAGL 51
Q FS L LK+L+L L EAL P + VP+ + GL
Sbjct: 56 QAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE------GL 109
Query: 52 TRLSLAYLPVKVIPSQAFRGLNEVIKIEIS--QIDSLERIEANAFDNLLNLSEILIQNTK 109
+ L +L + R LN + ++ ++ + I AF NL +L + + N +
Sbjct: 110 SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNR 169
Query: 110 NLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVFS--SESNFILEICDNLHITTIPGN 167
++++ +F L L+ L + +++FP + E F N +I IP
Sbjct: 170 -IQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGF-----HNNNIKAIPEK 223
Query: 168 AFQGMNNESVTLKLYGNGFEEVQSHAFNG-TTLTSLELKENVHLEKMHNGAFRGATGPKT 226
AF G N T+ Y N + V AF L +L L + +++ + +G T +
Sbjct: 224 AFMG-NPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD--LKGTTSLEI 280
Query: 227 LDISSTKLQALPSYGLESIQRL--IATSSYSLKKLPSRETFVNLLEATLTY 275
L ++ ++ LPS + + RL + S +++LPS L E L +
Sbjct: 281 LTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQH 331
Score = 45.4 bits (106), Expect = 2e-04
Identities = 52/194 (26%), Positives = 89/194 (45%), Gaps = 11/194 (5%)
Query: 86 LERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVF 145
L I AF L +L +++QN + L I A LP L+ L + I P+ + F
Sbjct: 50 LSHIPGQAFSGLYSLKILMLQNNQ-LGGIPAEALWELPSLQSLRLDANLISLVPE--RSF 106
Query: 146 SSESNFILEICDNLHITTIPGNAFQGMNN-ESVTLKLYGNGFEEVQSHAF-NGTTLTSLE 203
S+ D+ +T IP A + +++TL L N + +AF N T+L L
Sbjct: 107 EGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL--NRISHIPDYAFQNLTSLVVLH 164
Query: 204 LKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRL--IATSSYSLKKLPS 261
L N ++ + +F G +TLD++ KLQ P + ++ RL + + ++K +P
Sbjct: 165 LHNN-RIQHLGTHSFEGLHNLETLDLNYNKLQEFP-VAIRTLGRLQELGFHNNNIKAIPE 222
Query: 262 RETFVNLLEATLTY 275
+ N L T+ +
Sbjct: 223 KAFMGNPLLQTIHF 236
>gi|62912470 leucine-rich repeat-containing G protein-coupled
receptor 6 isoform 1 [Homo sapiens]
Length = 967
Score = 147 bits (371), Expect = 3e-35
Identities = 134/553 (24%), Positives = 234/553 (42%), Gaps = 49/553 (8%)
Query: 102 EILIQNTKNLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVFSSESNFILEICDNLHI 161
EIL +R + G LPRL+ L + + I + P + + C L
Sbjct: 331 EILTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHR------------CQKLE- 377
Query: 162 TTIPGNAFQGMNNESVTLKLYGNGFEEVQSHAFNG-TTLTSLELKENVHLEKMHNGAFRG 220
+ L N E+ + F+ ++L +L+L N + +H AF
Sbjct: 378 ----------------EIGLQHNRIWEIGADTFSQLSSLQALDLSWNA-IRSIHPEAFST 420
Query: 221 ATGPKTLDISSTKLQALPSYGLESIQRLIATSSYSLKKLPSRETFVNLLEATLTYPSHCC 280
LD++ +L LP GL + L + +L + S+++F L + Y CC
Sbjct: 421 LHSLVKLDLTDNQLTTLPLAGLGGLMHLKLKGNLALSQAFSKDSFPKLRILEVPYAYQCC 480
Query: 281 A-------FRNLPTKEQNFSHSISENFSKQCESTV-RKVNNKTLYSSMLAESELSGWDYE 332
F+ E H E SK+ + R+ N Y L E +L D +
Sbjct: 481 PYGMCASFFKASGQWEAEDLHLDDEESSKRPLGLLARQAENH--YDQDLDELQLEMEDSK 538
Query: 333 YGFCLPKTPRCAPEPDAFNPCEDIMGYDFLRVLIWLINILAIMGN-MTVLFVLLTSRYKL 391
+ +C+P P F PCE + +R+ +W I +L+++ N + +L V L
Sbjct: 539 PH----PSVQCSPTPGPFKPCEYLFESWGIRLAVWAIVLLSVLCNGLVLLTVFAGGPVPL 594
Query: 392 TVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSGCSTAGFFTVFASE 451
+F++ ++ A+ G+ L+ASVD+ T GQ+ + W+TG GC GF V SE
Sbjct: 595 PPVKFVVGAIAGANTLTGISCGLLASVDALTFGQFSEYGARWETGLGCRATGFLAVLGSE 654
Query: 452 LSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKV 511
SV LT+ ++ +++ + L +LG + L A LPL V Y
Sbjct: 655 ASVLLLTLAAVQCSVSVSCVRAYGKSPSLGSVRAGVLGCLALAGLAAALPLASVGEYGAS 714
Query: 512 SICFPM--DVETTLSQVYILTILILNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAK 569
+C P + + + ++++N F ++ YIK+Y + + A D + +
Sbjct: 715 PLCLPYAPPEGQPAALGFTVALVMMNSFCFLVVAGAYIKLYCDLPRGDFEAV-WDCAMVR 773
Query: 570 KMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKT 629
+A LIF D P++F + ++ + +T K +L++ P+ +C NP LY +F
Sbjct: 774 HVAWLIFADGLLYCPVAFLSFASMLGLFPVTPEAVKSVLLVVLPLPACLNPLLYLLFNPH 833
Query: 630 FQRDFFLLLSKFG 642
F+ D L + G
Sbjct: 834 FRDDLRRLRPRAG 846
Score = 56.2 bits (134), Expect = 1e-07
Identities = 67/265 (25%), Positives = 117/265 (44%), Gaps = 30/265 (11%)
Query: 30 CPEPCNCVPDGALRCPGPTAGLTRLSLAYLPVKVIPSQAFRGL--NEVIKIEISQI---- 83
CP PC+C DG + +A + L L+ +P + P A+ L N + +++
Sbjct: 35 CPAPCHCQEDGIML----SADCSELGLSAVPGDLDPLTAYLDLSMNNLTELQPGLFHHLR 90
Query: 84 ---------DSLERIEANAFDNLLNLSEILIQNTKNLRYIEPGAFINLPRLKYLSICNTG 134
+ L I AF L +L +++QN + L I A LP L+ L +
Sbjct: 91 FLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQ-LGGIPAEALWELPSLQSLRLDANL 149
Query: 135 IRKFPDVTKVFSSESNFILEICDNLHITTIPGNAFQGMNN-ESVTLKLYGNGFEEVQSHA 193
I P+ + F S+ D+ +T IP A + +++TL L N + +A
Sbjct: 150 ISLVPE--RSFEGLSSLRHLWLDDNALTEIPVRALNNLPALQAMTLAL--NRISHIPDYA 205
Query: 194 F-NGTTLTSLELKENVHLEKMHNGAFRGATGPKTLDISSTKLQALPSYGLESIQRL--IA 250
F N T+L L L N ++ + +F G +TLD++ KLQ P + ++ RL +
Sbjct: 206 FQNLTSLVVLHLHNN-RIQHLGTHSFEGLHNLETLDLNYNKLQEFP-VAIRTLGRLQELG 263
Query: 251 TSSYSLKKLPSRETFVNLLEATLTY 275
+ ++K +P + N L T+ +
Sbjct: 264 FHNNNIKAIPEKAFMGNPLLQTIHF 288
Score = 46.6 bits (109), Expect = 8e-05
Identities = 69/291 (23%), Positives = 120/291 (41%), Gaps = 33/291 (11%)
Query: 3 QRFSALQLLKLLLLLQPPLPRALREALCPEP-----------CNCVPDGALRCPGPTAGL 51
Q FS L LK+L+L L EAL P + VP+ + GL
Sbjct: 108 QAFSGLYSLKILMLQNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFE------GL 161
Query: 52 TRLSLAYLPVKVIPSQAFRGLNEVIKIEIS--QIDSLERIEANAFDNLLNLSEILIQNTK 109
+ L +L + R LN + ++ ++ + I AF NL +L + + N +
Sbjct: 162 SSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNR 221
Query: 110 NLRYIEPGAFINLPRLKYLSICNTGIRKFPDVTKVFS--SESNFILEICDNLHITTIPGN 167
++++ +F L L+ L + +++FP + E F N +I IP
Sbjct: 222 -IQHLGTHSFEGLHNLETLDLNYNKLQEFPVAIRTLGRLQELGF-----HNNNIKAIPEK 275
Query: 168 AFQGMNNESVTLKLYGNGFEEVQSHAFNG-TTLTSLELKENVHLEKMHNGAFRGATGPKT 226
AF G N T+ Y N + V AF L +L L + +++ + +G T +
Sbjct: 276 AFMG-NPLLQTIHFYDNPIQFVGRSAFQYLPKLHTLSLNGAMDIQEFPD--LKGTTSLEI 332
Query: 227 LDISSTKLQALPSYGLESIQRL--IATSSYSLKKLPSRETFVNLLEATLTY 275
L ++ ++ LPS + + RL + S +++LPS L E L +
Sbjct: 333 LTLTRAGIRLLPSGMCQQLPRLRVLELSHNQIEELPSLHRCQKLEEIGLQH 383
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 79.7 bits (195), Expect = 8e-15
Identities = 81/324 (25%), Positives = 136/324 (41%), Gaps = 36/324 (11%)
Query: 345 PEPDAFNPCEDIMGYDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFA 404
PEP+ + + I L + I +L ++GN V+ V++ + TV F + NL+ A
Sbjct: 36 PEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVA 95
Query: 405 DFCMGLYLLLIASVDSQTKGQYYNHAIDWQTGSG-CSTAGFFTVFASELSVYTLTVITLE 463
D + L Y +W+ G C + A ++S TLTVI L+
Sbjct: 96 DLLVNTLCLPFTLT--------YTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALD 147
Query: 464 RWHTITYAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSIC--------- 514
R I Y HL+ K+ R + LI+ W S+L+A PL Y + I
Sbjct: 148 RHRCIVY--HLESKISKRISFLIIGLAWGISALLAS-PLAIFREYSLIEIIPDFEIVACT 204
Query: 515 --FPMDVETTLSQVYIL-TILILNVVAFFIICACYIKIYFAVRNPELMATNKD------T 565
+P + ++ VY L ++LIL V+ II Y +I+ ++N D
Sbjct: 205 EKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQ 264
Query: 566 KIAKKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPINSC---ANPFL 622
K K + ++ P+ F ++ ++ + K++ +F+ I C ANP L
Sbjct: 265 KTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLL 324
Query: 623 YAIFTKTFQRDFFLLLSKFGCCKR 646
Y +++ F LS F C +R
Sbjct: 325 YGWMNSNYRKAF---LSAFRCEQR 345
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 77.0 bits (188), Expect = 5e-14
Identities = 71/300 (23%), Positives = 130/300 (43%), Gaps = 29/300 (9%)
Query: 352 PCEDIMGYDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFAD--FCMG 409
P D+ L + +++ I+ + GN V++V+L T+ + NL+ AD F +G
Sbjct: 36 PYYDLTSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLG 95
Query: 410 LYLLLIASVDSQTKGQYYNHAIDWQTGSG-CSTAGFFTVFASELSVYTLTVITLERWHTI 468
L L + + W G C S++ LTV++++R+ +
Sbjct: 96 LPFLAMQVA-----------LVHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAV 144
Query: 469 TYAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLV---GV-SNYMKVSIC---FPMDVET 521
+ I + R R A +I + W S L+ +LP++ G+ SN S C +P +
Sbjct: 145 VHPIKSAKWRRPRTAKMITMAVWGVS-LLVILPIMIYAGLRSNQWGRSSCTINWPGESGA 203
Query: 522 TLSQVYILTILILNVVAFFIICACYIKIYFAVRNPELMATNK-----DTKIAKKMAILIF 576
+ I T ++ +V IIC CY+ I V++ + + + K+ + ++I++
Sbjct: 204 WYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVA 263
Query: 577 TDFTCMAPISFFAISAAFKV--PLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDF 634
C P F +S+ P + +V+ NSCANP LYA + F++ F
Sbjct: 264 VFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSF 323
>gi|32307152 oxytocin receptor [Homo sapiens]
Length = 389
Score = 71.6 bits (174), Expect = 2e-12
Identities = 82/350 (23%), Positives = 142/350 (40%), Gaps = 62/350 (17%)
Query: 365 LIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKG 424
++ LI +LA+ GN VL L T+R K + F M +LS AD + ++ +L + T
Sbjct: 45 VLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFR 104
Query: 425 QYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAI 484
Y + C + V S Y L +++L+R I + + LR R
Sbjct: 105 FYGPDLL-------CRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPL---RSLRRRTDR 154
Query: 485 LIMLGGWLFSSLIAMLPLVGVSNYMKVSI----CFPMDVETTLSQVYILTI-LILNVVAF 539
L +L WL L+A P V + + +V+ C+ + ++ + YI I L + +V
Sbjct: 155 LAVLATWL-GCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPV 213
Query: 540 FIICACYIKIYF--------------AVRNPELMATNKDTKIA----------------- 568
++ ACY I F A PE A ++A
Sbjct: 214 IVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRT 273
Query: 569 -KKMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFT 627
K I++ C P F + + + ++ ++++L +NSC NP++Y +FT
Sbjct: 274 VKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVMLLASLNSCCNPWIYMLFT 333
Query: 628 KTFQRDFFLLLSKFGCCKRRAELYRRKDFSAYTSNCKNGFTGSNKPSQST 677
F L+ +F CC ++Y + G T ++K S S+
Sbjct: 334 GHL---FHELVQRFLCCS-----------ASYLKGRRLGETSASKKSNSS 369
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 69.7 bits (169), Expect = 9e-12
Identities = 75/289 (25%), Positives = 117/289 (40%), Gaps = 34/289 (11%)
Query: 362 LRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQ 421
L +I L+ + ++GN+TV++ SR T + NL+ +DF M + S
Sbjct: 73 LGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSL 132
Query: 422 TKGQYYNHAIDWQTG-SGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRL 480
K W G +GC F S+ TLT I L+R+ IT +
Sbjct: 133 YK--------QWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASK 184
Query: 481 RHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSI--CFPMDVETTLSQVYILTILILNVVA 538
R A ++LG WL++ ++ P G S Y+ + D + V T+L+ V
Sbjct: 185 RRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVF 244
Query: 539 F---FIICACYIKIYFAVRNP------------------ELMATNKDTKIAKKMAILIFT 577
F II CYI I+ A+R + + K+AK M ++I
Sbjct: 245 FLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECKMAKIMLLVILL 304
Query: 578 DFTCMAPISFFAISA-AFKVPLITVTNSKVLLVLFYPINSCANPFLYAI 625
AP S A+ A A ++T S V V+ ++ NP +YAI
Sbjct: 305 FVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVI-AKASAIHNPIIYAI 352
>gi|149944554 somatostatin receptor 4 [Homo sapiens]
Length = 388
Score = 69.3 bits (168), Expect = 1e-11
Identities = 75/291 (25%), Positives = 127/291 (43%), Gaps = 29/291 (9%)
Query: 368 LINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYY 427
L+ ++ ++GN V+FV+L T + NL+ AD L++L + V S ++
Sbjct: 56 LVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVAD---ELFMLSVPFVASSAALRH- 111
Query: 428 NHAIDWQTGSG-CSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILI 486
W GS C SV+ LTV++++R+ + + + R A LI
Sbjct: 112 -----WPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLI 166
Query: 487 MLGGWLFSSLIAMLPLVGVSN--------YMKVSICFPMDVETTLSQVYILTILILNVVA 538
LG WL +SL+ LP+ ++ + ++ +P + + VY T L+ ++
Sbjct: 167 NLGVWL-ASLLVTLPIAIFADTRPARGGQAVACNLQWPHPAWSAVFVVY--TFLLGFLLP 223
Query: 539 FFIICACYIKIYFAVRNPELMA-----TNKDTKIAKKMAILIFTDFTCMAPISFFAISAA 593
I CY+ I +R L A + KI + + +++ C P +
Sbjct: 224 VLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNL 283
Query: 594 FKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFGCC 644
F V + T + V L+L Y NSCANP LY + F+R FF + CC
Sbjct: 284 F-VTSLDATVNHVSLILSY-ANSCANPILYGFLSDNFRR-FFQRVLCLRCC 331
>gi|4557857 somatostatin receptor 1 [Homo sapiens]
Length = 391
Score = 68.6 bits (166), Expect = 2e-11
Identities = 69/284 (24%), Positives = 119/284 (41%), Gaps = 25/284 (8%)
Query: 368 LINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYY 427
++ ++ + GN V++V+L T + NL+ AD LL+ SV
Sbjct: 67 VVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADE------LLMLSVPFLVTSTLL 120
Query: 428 NHAIDWQTGSG-CSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILI 486
H W G+ C S+Y LTV++++R+ + + I + R A ++
Sbjct: 121 RH---WPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVV 177
Query: 487 MLGGWLFSSLIAMLPLVGVS-------NYMKVSICFPMDVETTLSQVYILTILILNVVAF 539
LG W+ SL+ +LP+V S + ++ P + L + T L+ ++
Sbjct: 178 NLGVWVL-SLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPV 236
Query: 540 FIICACYIKIYFAVRNPELMA-----TNKDTKIAKKMAILIFTDFTCMAPISFFAISAAF 594
IC CY+ I +R L A + KI + +++ C P + F
Sbjct: 237 GAICLCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVF 296
Query: 595 KVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDFFLLL 638
T S++ ++L Y NSCANP LY + F+R F +L
Sbjct: 297 -AEQDDATVSQLSVILGY-ANSCANPILYGFLSDNFKRSFQRIL 338
>gi|71999131 opsin 3 [Homo sapiens]
Length = 402
Score = 67.0 bits (162), Expect = 6e-11
Identities = 75/305 (24%), Positives = 122/305 (40%), Gaps = 46/305 (15%)
Query: 359 YDFLRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASV 418
Y+ L +L+ I +L + N+ VL + + T L+ N+S +D + L+ + V
Sbjct: 41 YERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFV 100
Query: 419 DSQTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKL 478
G W T GC GF +S+ TLTV+ ER+ + +A ++
Sbjct: 101 SCLRNGWV------WDT-VGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSW 153
Query: 479 RLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSICFPMDV------------ETTLSQV 526
R I WL+S A PL+G + Y+ +DV + S
Sbjct: 154 AWRAITYI----WLYSLAWAGAPLLGWNRYI-------LDVHGLGCTVDWKSKDANDSSF 202
Query: 527 YILTILILNVVAFFIICACYIKIYFAVRN----------PELMATNKDTKIAKKMAILIF 576
+ L VV +I CY I +++R + + K+AK ++IF
Sbjct: 203 VLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIF 262
Query: 577 TDFTCMAP---ISFFAISAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRD 633
T C P I F ++ L+T T S ++ LF N+ NP +Y + F+R
Sbjct: 263 TFLVCWMPYIVICFLVVNG--HGHLVTPTIS-IVSYLFAKSNTVYNPVIYVFMIRKFRRS 319
Query: 634 FFLLL 638
LL
Sbjct: 320 LLQLL 324
>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
Length = 384
Score = 66.6 bits (161), Expect = 7e-11
Identities = 70/292 (23%), Positives = 114/292 (39%), Gaps = 42/292 (14%)
Query: 371 ILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHA 430
IL + GN+ ++ ++L + V L+ NLSF+D + + L V Y
Sbjct: 52 ILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFV--------YTLM 103
Query: 431 IDWQTGSG-CSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLG 489
W G C F + +S+++L +I +ER I + RHA + +
Sbjct: 104 DHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINP--RGWRPNNRHAYVGIAV 161
Query: 490 GWLFSSLIAMLPL-------------VGVSNYMKVSIC---FPMDVETTLSQVYILTILI 533
W+ ++ + LP V + Y +C FP D +L +
Sbjct: 162 IWVL-AVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQY 220
Query: 534 LNVVAFFIICACYIKIYFAVRN----PELMATNK----DTKIAKKMAILIFTDF-TCMAP 584
+ F I CY KIY ++ + M NK +TK M + I F C P
Sbjct: 221 FGPLCFIFI--CYFKIYIRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLP 278
Query: 585 ISFFAISAAFKVPLITVTNSKVLLVLFY---PINSCANPFLYAIFTKTFQRD 633
++ F + +I N +L +L + I++C NP Y K FQRD
Sbjct: 279 LTIFNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRD 330
>gi|148228829 G protein-coupled receptor 1 [Homo sapiens]
Length = 355
Score = 66.6 bits (161), Expect = 7e-11
Identities = 71/289 (24%), Positives = 124/289 (42%), Gaps = 34/289 (11%)
Query: 364 VLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTK 423
VL L +L I GN V++ ++K TV NL+ ADF L+L L S
Sbjct: 43 VLYCLAFVLGIPGNAIVIW-FTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYIS------ 95
Query: 424 GQYYNHAIDWQTGSGCSTAGFFTVFASEL-SVYTLTVITLERWHTITYAIHLDQKLRLRH 482
Y W G A FT + SV+ LTVI+L+ + + + + + L++
Sbjct: 96 --YVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKN 153
Query: 483 AILIMLGGWLFSSLIA--MLPLVGVSNYMKVSICF----PMDVETTLSQVYILT---ILI 533
++++++ WL +SLI L + ++C+ D + TL + ++LT +I
Sbjct: 154 SLIVIIFIWLLASLIGGPALYFRDTVEFNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFII 213
Query: 534 LNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAI--- 590
+ + CY+ + F V+ ++ +++ + +++ C P F+I
Sbjct: 214 GYLFPLLTMSICYLCLIFKVKKRSILISSRH---FWTILVVVVAFVVCWTPYHLFSIWEL 270
Query: 591 -----SAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDF 634
S + V + S L L NSC NP LY + +K FQ F
Sbjct: 271 TIHHNSYSHHVMQAGIPLSTGLAFL----NSCLNPILYVLISKKFQARF 315
>gi|36951012 G protein-coupled receptor 1 [Homo sapiens]
Length = 355
Score = 66.6 bits (161), Expect = 7e-11
Identities = 71/289 (24%), Positives = 124/289 (42%), Gaps = 34/289 (11%)
Query: 364 VLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTK 423
VL L +L I GN V++ ++K TV NL+ ADF L+L L S
Sbjct: 43 VLYCLAFVLGIPGNAIVIW-FTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYIS------ 95
Query: 424 GQYYNHAIDWQTGSGCSTAGFFTVFASEL-SVYTLTVITLERWHTITYAIHLDQKLRLRH 482
Y W G A FT + SV+ LTVI+L+ + + + + + L++
Sbjct: 96 --YVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKN 153
Query: 483 AILIMLGGWLFSSLIA--MLPLVGVSNYMKVSICF----PMDVETTLSQVYILT---ILI 533
++++++ WL +SLI L + ++C+ D + TL + ++LT +I
Sbjct: 154 SLIVIIFIWLLASLIGGPALYFRDTVEFNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFII 213
Query: 534 LNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAI--- 590
+ + CY+ + F V+ ++ +++ + +++ C P F+I
Sbjct: 214 GYLFPLLTMSICYLCLIFKVKKRSILISSRH---FWTILVVVVAFVVCWTPYHLFSIWEL 270
Query: 591 -----SAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQRDF 634
S + V + S L L NSC NP LY + +K FQ F
Sbjct: 271 TIHHNSYSHHVMQAGIPLSTGLAFL----NSCLNPILYVLISKKFQARF 315
>gi|4557865 somatostatin receptor 5 [Homo sapiens]
Length = 364
Score = 65.9 bits (159), Expect = 1e-10
Identities = 69/283 (24%), Positives = 117/283 (41%), Gaps = 24/283 (8%)
Query: 364 VLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTK 423
VL L+ + GN V++V+L TV + NL+ AD LY+L + + +Q
Sbjct: 45 VLYLLVCAAGLGGNTLVIYVVLRFAKMKTVTNIYILNLAVADV---LYMLGLPFLATQ-- 99
Query: 424 GQYYNHAIDWQTGSG-CSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRH 482
N A W G C SV+ LTV++++R+ + + + + R R
Sbjct: 100 ----NAASFWPFGPVLCRLVMTLDGVNQFTSVFCLTVMSVDRYLAVVHPLSSARWRRPRV 155
Query: 483 AILIMLGGWLFSSLIAMLPLVGVSNYMKVSIC---FPMDVETTLSQVYILTILILNVVAF 539
A L W+ S L LPL+ ++ + C +P V + I T ++
Sbjct: 156 AKLASAAAWVLS-LCMSLPLLVFADVQEGGTCNASWPEPVGLWGAVFIIYTAVLGFFAPL 214
Query: 540 FIICACYIKIYFAVRNPEL----MATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAFK 595
+IC CY+ I VR + + + K+ + + +++ C P FF ++
Sbjct: 215 LVICLCYLLIVVKVRAAGVRVGCVRRRSERKVTRMVLVVVLVFAGCWLP--FFTVNIVNL 272
Query: 596 VPLITVTNSKVLLVLFYPI----NSCANPFLYAIFTKTFQRDF 634
+ + L F I NSCANP LY + F++ F
Sbjct: 273 AVALPQEPASAGLYFFVVILSYANSCANPVLYGFLSDNFRQSF 315
>gi|161484640 neuromedin B receptor [Homo sapiens]
Length = 390
Score = 65.5 bits (158), Expect = 2e-10
Identities = 76/341 (22%), Positives = 137/341 (40%), Gaps = 48/341 (14%)
Query: 365 LIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKG 424
L LI + ++GN+ ++ + +T+ +VP + NL+ D LLL+ V
Sbjct: 49 LYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDL-----LLLLTCVPVDASR 103
Query: 425 QYYNHAIDWQTGS-GCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHA 483
+++ +W G GC + + +SV+TLT ++ +R+ I + + L
Sbjct: 104 YFFD---EWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRT 160
Query: 484 ILIMLGGWLFSSLIAMLPLVGVSNYMKVS--------ICFPMDVETTLSQ---------V 526
+ +G W+ S L+A +P S ++S C P L V
Sbjct: 161 CVKAMGIWVVSVLLA-VPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLV 219
Query: 527 YILTILILNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAKKMA--ILIFTD--FTCM 582
Y L L + + ++ I IK + T K + K++A +L+F C
Sbjct: 220 YFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCW 279
Query: 583 APISFFAISAAFKVPLITVTNSKVLLVLFYPI----NSCANPFLYAIFTKTFQRDFFLLL 638
P + +F I + +++ L + NSC NPF + +++F+R F L
Sbjct: 280 FPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQL 339
Query: 639 SKFGCCKRRAELYRRKDF---------SAYTSNCKNGFTGS 670
CC R++ R + ++ SN KN T S
Sbjct: 340 ----CCGRKSYQERGTSYLLSSSAVRMTSLKSNAKNMVTNS 376
>gi|30023826 G-protein coupled purinergic receptor P2Y8 [Homo
sapiens]
Length = 359
Score = 65.1 bits (157), Expect = 2e-10
Identities = 88/342 (25%), Positives = 147/342 (42%), Gaps = 47/342 (13%)
Query: 362 LRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQ 421
L V+ L+ ++I GN+ L+VL + M NLS D L++ASV
Sbjct: 26 LPVVYSLVAAVSIPGNLFSLWVLCRRMGPRSPSVIFMINLSVTD-------LMLASV--- 75
Query: 422 TKGQYYNHAI--DWQTG---SGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQ 476
Q Y H W G T F+ S S+ T+T I++ER+ + Y + +
Sbjct: 76 LPFQIYYHCNRHHWVFGVLLCNVVTVAFYANMYS--SILTMTCISVERFLGVLYPLSSKR 133
Query: 477 KLRLRHAILIMLGGWLFSSLIAMLPLVGVS-----NYMKVSICFPMDVETTLSQ-----V 526
R R+A+ G WL L A+ PL + + + CF + T L V
Sbjct: 134 WRRRRYAVAACAGTWLL-LLTALSPLARTDLTYPVHALGIITCFDVLKWTMLPSVAMWAV 192
Query: 527 YILTI-LILNVVAFFIICACY-IKIYFAVRNPELMATNKDTKIAKKMAILIFTDFTCMAP 584
++ TI ++L ++ F I ACY I +R E + + A+++ TC AP
Sbjct: 193 FLFTIFILLFLIPFVITVACYTATILKLLRTEEAHGREQRRRAVGLAAVVLLAFVTCFAP 252
Query: 585 ISFFAISAAFKVPLITVTNSKV--LLVLFYPINSCANPFLYAIFTKTFQRDFFLLLSKFG 642
+F ++ + V L + +N+C +PF+Y ++ FQ L L ++
Sbjct: 253 NNFVLLAHIVSRLFYGKSYYHVYKLTLCLSCLNNCLDPFVYYFASREFQ----LRLREYL 308
Query: 643 CCKR--RAELYRRKD--FSAYTSNCKN-------GFTGSNKP 673
C+R R L R++ FSA T++ ++ G G+ +P
Sbjct: 309 GCRRVPRDTLDTRRESLFSARTTSVRSEAGAHPEGMEGATRP 350
>gi|50233854 olfactory receptor, family 14, subfamily A, member 16
[Homo sapiens]
Length = 309
Score = 65.1 bits (157), Expect = 2e-10
Identities = 62/283 (21%), Positives = 123/283 (43%), Gaps = 29/283 (10%)
Query: 364 VLIWLINILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTK 423
+L LI + A+MGN+ ++ + + T F + NLSF D C L+ + + S
Sbjct: 27 ILFLLIYLCALMGNVLIIMITTLDHHLHTPVYFFLKNLSFLDLC----LISVTAPKSIAN 82
Query: 424 GQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHA 483
+N++I + GC + F + ++ + LTV++ +R+ I + +H D +
Sbjct: 83 SLIHNNSISF---LGCVSQVFLLLSSASAELLLLTVMSFDRYTAICHPLHYDVIMDRSTC 139
Query: 484 ILIMLGGWLFSSLIAMLPLVGV-------SNYMKVSIC-FPMDVETTLSQVYI--LTILI 533
+ WL+ LIA++ G SN + C P + + S+ I + +++
Sbjct: 140 VQRATVSWLYGGLIAVMHTAGTFSLSYCGSNMVHQFFCDIPQLLAISCSENLIREIALIL 199
Query: 534 LNVV----AFFIICACYIKIYFAVRN-PELMATNKDTKIAKKMAILIFTDFTCMAPISFF 588
+NVV F +I Y+ ++ V+ P +K I +++ F I++
Sbjct: 200 INVVLDFCCFIVIIITYVHVFSTVKKIPSTEGQSKAYSICLPHLLVVL--FLSTGFIAY- 256
Query: 589 AISAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAIFTKTFQ 631
+ A + P I V+ V + + NP +Y++ K +
Sbjct: 257 -LKPASESPSIL---DAVISVFYTMLPPTFNPIIYSLRNKAIK 295
>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
Length = 489
Score = 64.7 bits (156), Expect = 3e-10
Identities = 76/300 (25%), Positives = 120/300 (40%), Gaps = 45/300 (15%)
Query: 362 LRVLIWLINILAIMGNMTVLF-----------VLLTSRYKLTVPRFLMCNLSFADFCMGL 410
L +I L+ + ++GN+TV++ V++ SR T + NL+ +DF M
Sbjct: 73 LGTVILLVGLTGMLGNLTVIYTFCRAVLRGVTVMMQSRSLRTPANMFIINLAVSDFLMSF 132
Query: 411 YLLLIASVDSQTKGQYYNHAIDWQTG-SGCSTAGFFTVFASELSVYTLTVITLERWHTIT 469
+ S K W G +GC F S+ TLT I L+R+ IT
Sbjct: 133 TQAPVFFTSSLYK--------QWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVIT 184
Query: 470 YAIHLDQKLRLRHAILIMLGGWLFSSLIAMLPLVGVSNYMKVSI--CFPMDVETTLSQVY 527
+ R A ++LG WL++ ++ P G S Y+ + D + V
Sbjct: 185 RPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVR 244
Query: 528 ILTILILNVVAF---FIICACYIKIYFAVRNP------------------ELMATNKDTK 566
T+L+ V F II CYI I+ A+R + + K
Sbjct: 245 AYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLWQRQRLQSECK 304
Query: 567 IAKKMAILIFTDFTCMAPISFFAISA-AFKVPLITVTNSKVLLVLFYPINSCANPFLYAI 625
+AK M ++I AP S A+ A A ++T S V V+ ++ NP +YAI
Sbjct: 305 MAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVI-AKASAIHNPIIYAI 363
>gi|52317239 olfactory receptor, family 4, subfamily D, member 10
[Homo sapiens]
Length = 311
Score = 64.3 bits (155), Expect = 4e-10
Identities = 68/285 (23%), Positives = 115/285 (40%), Gaps = 43/285 (15%)
Query: 362 LRVLIWLINILAIMGNMTVLFVLLTSRYKLTVPR-FLMCNLSFADFCMGLYLLLIASVD- 419
L + + L+ + ++GN+ ++ V +T +L P FL+ NLS AD C + VD
Sbjct: 27 LFLFLLLVYVTTLLGNLLIM-VTVTCESRLHTPMYFLLHNLSIADICFSSITVPKVLVDL 85
Query: 420 -SQTKGQYYNHAIDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKL 478
S+ K +NH C T F + V++L+V+ L+R+ I+ +H +
Sbjct: 86 LSERKTISFNH---------CFTQMFLFHLIGGVDVFSLSVMALDRYVAISKPLHYATIM 136
Query: 479 RLRHAILIMLGGWLFS--------SLIAMLPLVGVSNYMKVSICFPMDVETTL----SQV 526
H I + + WL SL+ LP G N + C DV L + +
Sbjct: 137 SRDHCIGLTVAAWLGGFVHSIVQISLLLPLPFCG-PNVLDTFYC---DVHRVLKLAHTDI 192
Query: 527 YILTIL------ILNVVAFFIICACYIKIYFAVRNPELMATNKDTKIAKKMAILIFTDFT 580
+IL +L +L + FF++ YI I L ++ AI T
Sbjct: 193 FILELLMISNNGLLTTLWFFLLLVSYIVI--------LSLPKSQAGEGRRKAISTCTSHI 244
Query: 581 CMAPISFFAISAAFKVPLITVTNSKVLLVLFYPINSCANPFLYAI 625
+ + F + P + K + V F I+ NP +Y +
Sbjct: 245 TVVTLHFVPCIYVYARPFTALPMDKAISVTFTVISPLLNPLIYTL 289
>gi|157426873 tachykinin receptor 2 [Homo sapiens]
Length = 398
Score = 62.4 bits (150), Expect = 1e-09
Identities = 73/337 (21%), Positives = 130/337 (38%), Gaps = 42/337 (12%)
Query: 371 ILAIMGNMTVLFVLLTSRYKLTVPRFLMCNLSFADFCMGLYLLLIASVDSQTKGQYYNHA 430
++A+ GN V++++L R TV + + NL+ AD CM A+ ++ Y +H
Sbjct: 45 LVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCM-------AAFNAAFNFVYASHN 97
Query: 431 IDWQTGSGCSTAGFFTVFASELSVYTLTVITLERWHTITYAIHLDQKLRLRHAILIMLGG 490
I + + C F + A +S+Y++T I +R+ I + +L ++ G
Sbjct: 98 IWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHP--FQPRLSAPSTKAVIAGI 155
Query: 491 WLFSSLIAMLPLVGVSNYM-----KVSICFPMDV-ETTLSQVYILTILILNVVAFFIICA 544
WL + +A + M K + +P D TL +++ I ++ + ++
Sbjct: 156 WLVALALASPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFV 215
Query: 545 CYIKIYFAV----------RNPELMATNKDTKIAKKMAILIFTDFTCMAPISFFAISAAF 594
Y I + L K K M +++ T C P + I +F
Sbjct: 216 AYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSF 275
Query: 595 KVPLIT-VTNSKVLLVLFYPINSCA--NPFLYAIFTKTFQRDFFLLLSKFGCC------- 644
+ + +V L LF+ S NP +Y F+ F L F CC
Sbjct: 276 QEDIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFRSGFRL---AFRCCPWVTPTK 332
Query: 645 KRRAELYRRKDFSAYTSNCKNGFT----GSNKPSQST 677
+ + EL S + C T G PS++T
Sbjct: 333 EDKLELTPTTSLSTRVNRCHTKETLFMAGDTAPSEAT 369
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,565,829
Number of Sequences: 37866
Number of extensions: 1057084
Number of successful extensions: 4847
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 170
Number of HSP's successfully gapped in prelim test: 473
Number of HSP's that attempted gapping in prelim test: 3897
Number of HSP's gapped (non-prelim): 970
length of query: 699
length of database: 18,247,518
effective HSP length: 109
effective length of query: 590
effective length of database: 14,120,124
effective search space: 8330873160
effective search space used: 8330873160
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.