Search of human proteins with 10190716

Search of human proteins with 10190716

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10190716 spindle pole body component 25 [Homo sapiens]
         (224 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10190716 spindle pole body component 25 [Homo sapiens]             439   e-124
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             46   2e-05
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         46   3e-05
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         46   3e-05
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    44   9e-05
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         43   2e-04
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         43   2e-04
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         43   2e-04
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         43   2e-04
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         43   2e-04
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         43   2e-04
gi|71061468 centromere protein E [Homo sapiens]                        43   2e-04
gi|58530842 desmoplakin isoform II [Homo sapiens]                      41   7e-04
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]            41   7e-04
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]            40   0.001
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]            40   0.001
gi|13699824 kinesin family member 11 [Homo sapiens]                    40   0.001
gi|122891870 melanoma inhibitory activity family, member 3 [Homo...    40   0.002
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     40   0.002
gi|55770834 centromere protein F [Homo sapiens]                        40   0.002
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    39   0.003
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    39   0.004
gi|94721321 coiled-coil domain containing 11 [Homo sapiens]            39   0.004
gi|157671919 hypothetical protein LOC374864 isoform 1 [Homo sapi...    39   0.004
gi|157671917 hypothetical protein LOC374864 isoform 2 [Homo sapi...    39   0.004
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       39   0.005
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       39   0.005
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        39   0.005
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        39   0.005
gi|45446749 kinesin family member 5A [Homo sapiens]                    39   0.005

>gi|10190716 spindle pole body component 25 [Homo sapiens]
          Length = 224

 Score =  439 bits (1129), Expect = e-124
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MVEDELALFDKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEM 60
           MVEDELALFDKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEM
Sbjct: 1   MVEDELALFDKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEM 60

Query: 61  FLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTA 120
           FLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTA
Sbjct: 61  FLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTA 120

Query: 121 NKANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFSLHLNEAR 180
           NKANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFSLHLNEAR
Sbjct: 121 NKANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFSLHLNEAR 180

Query: 181 DYEVSDSAPHLEGLAEFQENVRKTNNFSAFLANVRKAFTATVYN 224
           DYEVSDSAPHLEGLAEFQENVRKTNNFSAFLANVRKAFTATVYN
Sbjct: 181 DYEVSDSAPHLEGLAEFQENVRKTNNFSAFLANVRKAFTATVYN 224


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 7/134 (5%)

Query: 5    ELALFDKSINEFWNKF-KSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMV--EMF 61
            ELA   + I+   N + KS +T  Q+    D Y    +  A +  +K  EE+  +  E  
Sbjct: 1006 ELAAEKEKISVLQNNYEKSQETFKQLQS--DFYGRESELLATRQDLKSVEEKLSLAQEDL 1063

Query: 62   LEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYS-RKKETISTA 120
            +  +NQI  QNKLIQE K     L  +   K+Q+L+     +QD+++E S ++KE ++  
Sbjct: 1064 ISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEK 1123

Query: 121  NK-ANAERLKRLQK 133
            +K A  E +K  Q+
Sbjct: 1124 SKLAEIEEIKCRQE 1137



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 28/120 (23%), Positives = 63/120 (52%), Gaps = 6/120 (5%)

Query: 2   VEDELALFDKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLK---EEERMV 58
           V+D+L+    S+    ++F+  +   + A L    + + K    +L V+++   +E++ +
Sbjct: 858 VKDKLSKVSDSLKNSKSEFEKENQKGKAAIL--DLEKTCKELKHQLQVQMENTLKEQKEL 915

Query: 59  EMFLEYQNQISRQNKL-IQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETI 117
           +  LE + + S Q KL +   ++ L++    +K  ++E + L  NI +LK+   +KK+ I
Sbjct: 916 KKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQI 975



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 37/166 (22%), Positives = 69/166 (41%), Gaps = 33/166 (19%)

Query: 3   EDELALFDKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFL 62
           +D +   + S+NE  ++   +        ++      IKA  E L   L  E        
Sbjct: 613 QDRVLSLETSVNELNSQLNESKEKVSQLDIQ------IKAKTELL---LSAEAAKTAQRA 663

Query: 63  EYQNQISRQNKLIQEKKDNLLKL-------IAEVKGKKQELEVLTANIQDLKEEY----- 110
           + QN +      +Q+K+  L K+        A+++ K++    L +++++ KE+Y     
Sbjct: 664 DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723

Query: 111 --------SRKKETISTANKANAER-LKRLQKSADLYKDRLGLEIR 147
                    +K E  S   KA+ E+ L+ LQ+   L  D   LE+R
Sbjct: 724 KTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTD---LELR 766



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 14/116 (12%)

Query: 35  TYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQ 94
           T  D++    E+ S KLK+E + +      Q+Q +     I + +  L K   EV    Q
Sbjct: 235 TLMDNMTLERERESEKLKDECKKL------QSQYASSEATISQLRSELAKGPQEVAVYVQ 288

Query: 95  ELEVLTANIQDLKEE--------YSRKKETISTANKANAERLKRLQKSADLYKDRL 142
           EL+ L +++ +L ++          ++++      K N E + +    A L++  L
Sbjct: 289 ELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDL 344


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 50/194 (25%), Positives = 96/194 (49%), Gaps = 15/194 (7%)

Query: 16   FWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLI 75
            F  K ++T++      LR+   +  +A  E+L+V+L + E +++ + + +    RQ   I
Sbjct: 1883 FRQKQEATESLKCQEELRERLHEESRA-REQLAVELSKAEGVIDGYADEKTLFERQ---I 1938

Query: 76   QEKKDNLLKLIAEV---KGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQ 132
            QEK D + +L  E+     + QELE     IQ+ +E  SR+KE +    +A     + LQ
Sbjct: 1939 QEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKA--EAGPVEQQLLQ 1996

Query: 133  KSADLYKDRLGLEIR--KIYGE-KLQFIFTNIDPKNPESPFMFSLHLNEARDYEVSDSAP 189
            ++  L K++L ++ +  K+  + + Q     ID +   S F   + L + ++ E+ D   
Sbjct: 1997 ETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRF---IELEQEKNTELMDLRQ 2053

Query: 190  HLEGLAEFQENVRK 203
              + L +  E +RK
Sbjct: 2054 QNQALEKQLEKMRK 2067



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 26/117 (22%), Positives = 60/117 (51%), Gaps = 10/117 (8%)

Query: 45  EKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQ 104
           E+L+ K+ EEE+     LE +++++  +KL+ E ++ +++   E+K  K EL       +
Sbjct: 332 EELNTKIIEEEKKT---LELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKER 388

Query: 105 DLKEEYSRKKETISTANKAN-------AERLKRLQKSADLYKDRLGLEIRKIYGEKL 154
              EE  +   T+    K N        + ++R+++      ++L  E+ ++YG+++
Sbjct: 389 QSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQI 445



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 40/178 (22%), Positives = 81/178 (45%), Gaps = 13/178 (7%)

Query: 43   FAEKLSVKLKEEERMVEMFLEYQNQ--ISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLT 100
            FA+ +  K  E +++ E   + Q Q  I+  NK+I+EK + +  L  +++    + E + 
Sbjct: 2283 FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVK 2342

Query: 101  AN----IQDLKEEYSRKKETISTANKANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQF 156
             N    I+ L E   + ++ ++   +  +     L + AD  K +L +    +  EKL  
Sbjct: 2343 RNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDV----VIAEKLA- 2397

Query: 157  IFTNIDPKNPESPFMFSLHLNEARDYEVSDSAPHLEGLAEFQENVRKTNNFSAFLANV 214
            +   ++  N E  FM ++ L E  +++++     L  L   +E+V K  +      NV
Sbjct: 2398 LEQQVETANEEMTFMKNV-LKET-NFKMNQLTQELFSLKRERESVEKIQSIPENSVNV 2453



 Score = 32.0 bits (71), Expect = 0.44
 Identities = 38/174 (21%), Positives = 73/174 (41%), Gaps = 49/174 (28%)

Query: 3   EDELALFDKSINEFWNKFKSTDTSCQMAGLRD----------TYKDSIKAFAEKLSVKLK 52
           ED++ L + +INE     K  DT+ Q   L++            +  ++   E+LS   +
Sbjct: 485 EDQIKLMNVAINEL--NIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRE 542

Query: 53  EEERMVEMFLEYQNQISRQNKLI--------------QEKKDNLLKLIAEVKGKKQELEV 98
           + +R  +   E +++++  +K +              + +K+  LK  AEV   K +LE+
Sbjct: 543 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 602

Query: 99  LT---------------ANIQDLK--------EEYSRKKETISTANKANAERLK 129
           L                A ++ L+        EE S+ KE +   ++ N E+LK
Sbjct: 603 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLK 656



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 25/137 (18%)

Query: 28   QMAGLRDTYK---DSIKAFAEKLSVKLKEEE-RMVEMFLEY----------QNQISRQNK 73
            QM G + T K   +S K   E L   +++++ +M+EM +E           Q Q+S +  
Sbjct: 3100 QMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKM 3159

Query: 74   LIQEKKDNLL--KLIAEVKGKKQ-----ELEVLTANIQDLKEEYSRKKETISTANKANAE 126
            ++ E K  L   KL  E   K Q     ELE     ++D  +E     +T+++  K + E
Sbjct: 3160 VVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRE 3219

Query: 127  RLKRLQKSADLYKDRLG 143
                LQ + +  K +LG
Sbjct: 3220 ----LQWALEKEKAKLG 3232



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 30/163 (18%), Positives = 75/163 (46%), Gaps = 10/163 (6%)

Query: 21  KSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKD 80
           K      +++ L+D  +  + + +E++++++ E ++ +E+  + + +     + +QE + 
Sbjct: 691 KQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQL 750

Query: 81  NLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANK-----ANAERLKRL---- 131
               L  ++K K+ +L+   A ++        +K+T+    K     +  ERL  L    
Sbjct: 751 KTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIK 810

Query: 132 QKSAD-LYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFS 173
            KS D +++  + + I +    K Q I  N + +   + F F+
Sbjct: 811 SKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFA 853



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 24/101 (23%), Positives = 56/101 (55%), Gaps = 11/101 (10%)

Query: 37   KDSIKAFAEKLSVKLKEE-ERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQE 95
            K+++KA A  +  +L +E E++++  LE Q Q        ++ +D+L K   +VK  + +
Sbjct: 1980 KEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQA-------EKVRDDLQK---QVKALEID 2029

Query: 96   LEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSAD 136
            +E   +   +L++E + +   +   N+A  ++L++++K  D
Sbjct: 2030 VEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLD 2070



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 19/93 (20%), Positives = 48/93 (51%), Gaps = 2/93 (2%)

Query: 37   KDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQEL 96
            K  ++  AEK+   L+++ + +E  ++ + Q+SR  +L QEK   L+ L  + +  +++L
Sbjct: 2005 KLEVQCQAEKVRDDLQKQVKALE--IDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQL 2062

Query: 97   EVLTANIQDLKEEYSRKKETISTANKANAERLK 129
            E +   + +   +   +++      +   ++LK
Sbjct: 2063 EKMRKFLDEQAIDREHERDVFQQEIQKLEQQLK 2095


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 50/194 (25%), Positives = 96/194 (49%), Gaps = 15/194 (7%)

Query: 16   FWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLI 75
            F  K ++T++      LR+   +  +A  E+L+V+L + E +++ + + +    RQ   I
Sbjct: 1883 FRQKQEATESLKCQEELRERLHEESRA-REQLAVELSKAEGVIDGYADEKTLFERQ---I 1938

Query: 76   QEKKDNLLKLIAEV---KGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQ 132
            QEK D + +L  E+     + QELE     IQ+ +E  SR+KE +    +A     + LQ
Sbjct: 1939 QEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKA--EAGPVEQQLLQ 1996

Query: 133  KSADLYKDRLGLEIR--KIYGE-KLQFIFTNIDPKNPESPFMFSLHLNEARDYEVSDSAP 189
            ++  L K++L ++ +  K+  + + Q     ID +   S F   + L + ++ E+ D   
Sbjct: 1997 ETEKLMKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRF---IELEQEKNTELMDLRQ 2053

Query: 190  HLEGLAEFQENVRK 203
              + L +  E +RK
Sbjct: 2054 QNQALEKQLEKMRK 2067



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 26/117 (22%), Positives = 60/117 (51%), Gaps = 10/117 (8%)

Query: 45  EKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQ 104
           E+L+ K+ EEE+     LE +++++  +KL+ E ++ +++   E+K  K EL       +
Sbjct: 332 EELNTKIIEEEKKT---LELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKER 388

Query: 105 DLKEEYSRKKETISTANKAN-------AERLKRLQKSADLYKDRLGLEIRKIYGEKL 154
              EE  +   T+    K N        + ++R+++      ++L  E+ ++YG+++
Sbjct: 389 QSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQI 445



 Score = 38.1 bits (87), Expect = 0.006
 Identities = 40/178 (22%), Positives = 81/178 (45%), Gaps = 13/178 (7%)

Query: 43   FAEKLSVKLKEEERMVEMFLEYQNQ--ISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLT 100
            FA+ +  K  E +++ E   + Q Q  I+  NK+I+EK + +  L  +++    + E + 
Sbjct: 2275 FAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVK 2334

Query: 101  AN----IQDLKEEYSRKKETISTANKANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQF 156
             N    I+ L E   + ++ ++   +  +     L + AD  K +L +    +  EKL  
Sbjct: 2335 RNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSEEADSLKHQLDV----VIAEKLA- 2389

Query: 157  IFTNIDPKNPESPFMFSLHLNEARDYEVSDSAPHLEGLAEFQENVRKTNNFSAFLANV 214
            +   ++  N E  FM ++ L E  +++++     L  L   +E+V K  +      NV
Sbjct: 2390 LEQQVETANEEMTFMKNV-LKET-NFKMNQLTQELFSLKRERESVEKIQSIPENSVNV 2445



 Score = 32.0 bits (71), Expect = 0.44
 Identities = 38/174 (21%), Positives = 73/174 (41%), Gaps = 49/174 (28%)

Query: 3   EDELALFDKSINEFWNKFKSTDTSCQMAGLRD----------TYKDSIKAFAEKLSVKLK 52
           ED++ L + +INE     K  DT+ Q   L++            +  ++   E+LS   +
Sbjct: 485 EDQIKLMNVAINEL--NIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSRE 542

Query: 53  EEERMVEMFLEYQNQISRQNKLI--------------QEKKDNLLKLIAEVKGKKQELEV 98
           + +R  +   E +++++  +K +              + +K+  LK  AEV   K +LE+
Sbjct: 543 QIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEM 602

Query: 99  LT---------------ANIQDLK--------EEYSRKKETISTANKANAERLK 129
           L                A ++ L+        EE S+ KE +   ++ N E+LK
Sbjct: 603 LEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLK 656



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 25/137 (18%)

Query: 28   QMAGLRDTYK---DSIKAFAEKLSVKLKEEE-RMVEMFLEY----------QNQISRQNK 73
            QM G + T K   +S K   E L   +++++ +M+EM +E           Q Q+S +  
Sbjct: 3092 QMNGRKITLKREQESEKPSQELLEYNIQQKQSQMLEMQVELSSMKDRATELQEQLSSEKM 3151

Query: 74   LIQEKKDNLL--KLIAEVKGKKQ-----ELEVLTANIQDLKEEYSRKKETISTANKANAE 126
            ++ E K  L   KL  E   K Q     ELE     ++D  +E     +T+++  K + E
Sbjct: 3152 VVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRE 3211

Query: 127  RLKRLQKSADLYKDRLG 143
                LQ + +  K +LG
Sbjct: 3212 ----LQWALEKEKAKLG 3224



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 30/163 (18%), Positives = 75/163 (46%), Gaps = 10/163 (6%)

Query: 21  KSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKD 80
           K      +++ L+D  +  + + +E++++++ E ++ +E+  + + +     + +QE + 
Sbjct: 691 KQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQELQL 750

Query: 81  NLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANK-----ANAERLKRL---- 131
               L  ++K K+ +L+   A ++        +K+T+    K     +  ERL  L    
Sbjct: 751 KTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDSIK 810

Query: 132 QKSAD-LYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFS 173
            KS D +++  + + I +    K Q I  N + +   + F F+
Sbjct: 811 SKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFA 853



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 24/101 (23%), Positives = 56/101 (55%), Gaps = 11/101 (10%)

Query: 37   KDSIKAFAEKLSVKLKEE-ERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQE 95
            K+++KA A  +  +L +E E++++  LE Q Q        ++ +D+L K   +VK  + +
Sbjct: 1980 KEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQA-------EKVRDDLQK---QVKALEID 2029

Query: 96   LEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSAD 136
            +E   +   +L++E + +   +   N+A  ++L++++K  D
Sbjct: 2030 VEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLD 2070



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 19/93 (20%), Positives = 48/93 (51%), Gaps = 2/93 (2%)

Query: 37   KDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQEL 96
            K  ++  AEK+   L+++ + +E  ++ + Q+SR  +L QEK   L+ L  + +  +++L
Sbjct: 2005 KLEVQCQAEKVRDDLQKQVKALE--IDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQL 2062

Query: 97   EVLTANIQDLKEEYSRKKETISTANKANAERLK 129
            E +   + +   +   +++      +   ++LK
Sbjct: 2063 EKMRKFLDEQAIDREHERDVFQQEIQKLEQQLK 2095


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 6/123 (4%)

Query: 37   KDSIKAFAEKLSVKLKEEERMVEMF--LEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQ 94
            +DS+ A  EK+ V  K   +  E+    E  N +   NK+++E+K+ L + + +++ K +
Sbjct: 1239 QDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDLQQMQAKVR 1298

Query: 95   ELEVLTANIQDLKEEYSRKKETISTANKANAERLKRL----QKSADLYKDRLGLEIRKIY 150
            +LE+    +Q+   E S K   +    K   E +KR     Q      KD    E RK+ 
Sbjct: 1299 KLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHLVSQQKDPDTEEYRKLL 1358

Query: 151  GEK 153
             EK
Sbjct: 1359 SEK 1361



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 13/110 (11%)

Query: 28  QMAGLRDTYKDSIKAFAEKLSVKLKE-EERMVEMFLEYQNQISRQNKLIQEKKDNLLKLI 86
           QM GL+ T  + ++   E L  KLKE +E+   M  ++ N+++   KL      NL K  
Sbjct: 239 QMNGLK-TSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKL-----SNLYKSA 292

Query: 87  AEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSAD 136
           A+      + E  +  +    EE  +  +    ANKA  + L  +++S D
Sbjct: 293 AD------DSEAKSNELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKD 336



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 26/122 (21%), Positives = 55/122 (45%), Gaps = 16/122 (13%)

Query: 24   DTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDN-- 81
            D    ++ LR T ++ +    E+L       E+   M    +  ++++ ++ +E + N  
Sbjct: 933  DVDDLVSQLRQT-EEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIE 991

Query: 82   ------------LLKLIAEVKGKKQEL-EVLTANIQDLKEEYSRKKETISTANKANAERL 128
                        L K + EV+ +KQEL +     I+ ++++ S  K+T+S+      E L
Sbjct: 992  VRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEAL 1051

Query: 129  KR 130
            +R
Sbjct: 1052 QR 1053



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 22/94 (23%), Positives = 46/94 (48%), Gaps = 1/94 (1%)

Query: 47  LSVKLKEE-ERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQD 105
           L+ +LK + + ++ +  E  N+I      ++ KK+ + +L  ++ G K   E L  +++D
Sbjct: 197 LNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVED 256

Query: 106 LKEEYSRKKETISTANKANAERLKRLQKSADLYK 139
           L  +    KE  ++  +     L    K ++LYK
Sbjct: 257 LLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYK 290



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 25/117 (21%), Positives = 50/117 (42%), Gaps = 9/117 (7%)

Query: 21   KSTDTSCQMAGLRDTYKDSIKAFAE------KLSVKLKEEERMVEMFLEYQNQISRQNKL 74
            K  +TS Q +G       S++   E      +   K K  E  VE     Q  +S +   
Sbjct: 1454 KVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVE---NLQKTLSEKETE 1510

Query: 75   IQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRL 131
             +  ++  ++L +E+   +Q+L+  T   + L+++ + K+E    A  A   ++  L
Sbjct: 1511 ARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHL 1567



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 16/72 (22%), Positives = 39/72 (54%), Gaps = 5/72 (6%)

Query: 64  YQNQISRQNKLIQEKKDN--LLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTAN 121
           Y   +  Q++L+ EK +N  + K + E+    +E+E     ++  +EEY R ++ +++ +
Sbjct: 399 YNAYVETQDQLLLEKLENKRINKYLDEIV---KEVEAKAPILKRQREEYERAQKAVASLS 455

Query: 122 KANAERLKRLQK 133
               + +K +Q+
Sbjct: 456 VKLEQAMKEIQR 467


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 12/134 (8%)

Query: 3   EDELALFDKSINEFWNKFKSTDTSCQMAG---LRDTYKDSIKAFAEKLSVKLKEEERMVE 59
           E E+A  +K + E   K   TD     +    L+ + +  +   A KL   +KE+E++  
Sbjct: 765 EVEVAKLEKQLLE--EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHS 822

Query: 60  MFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETIST 119
             ++ ++++S+    ++ +K+N+  L+   K K+QE+  L    Q  +EE +  K    +
Sbjct: 823 EVVQIRSEVSQ----VKREKENIQTLL---KSKEQEVNELLQKFQQAQEELAEMKRYAES 875

Query: 120 ANKANAERLKRLQK 133
           ++K   ++ K++ +
Sbjct: 876 SSKLEEDKDKKINE 889


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 12/134 (8%)

Query: 3   EDELALFDKSINEFWNKFKSTDTSCQMAG---LRDTYKDSIKAFAEKLSVKLKEEERMVE 59
           E E+A  +K + E   K   TD     +    L+ + +  +   A KL   +KE+E++  
Sbjct: 754 EVEVAKLEKQLLE--EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHS 811

Query: 60  MFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETIST 119
             ++ ++++S+    ++ +K+N+  L+   K K+QE+  L    Q  +EE +  K    +
Sbjct: 812 EVVQIRSEVSQ----VKREKENIQTLL---KSKEQEVNELLQKFQQAQEELAEMKRYAES 864

Query: 120 ANKANAERLKRLQK 133
           ++K   ++ K++ +
Sbjct: 865 SSKLEEDKDKKINE 878


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 12/134 (8%)

Query: 3   EDELALFDKSINEFWNKFKSTDTSCQMAG---LRDTYKDSIKAFAEKLSVKLKEEERMVE 59
           E E+A  +K + E   K   TD     +    L+ + +  +   A KL   +KE+E++  
Sbjct: 733 EVEVAKLEKQLLE--EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHS 790

Query: 60  MFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETIST 119
             ++ ++++S+    ++ +K+N+  L+   K K+QE+  L    Q  +EE +  K    +
Sbjct: 791 EVVQIRSEVSQ----VKREKENIQTLL---KSKEQEVNELLQKFQQAQEELAEMKRYAES 843

Query: 120 ANKANAERLKRLQK 133
           ++K   ++ K++ +
Sbjct: 844 SSKLEEDKDKKINE 857


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 12/134 (8%)

Query: 3   EDELALFDKSINEFWNKFKSTDTSCQMAG---LRDTYKDSIKAFAEKLSVKLKEEERMVE 59
           E E+A  +K + E   K   TD     +    L+ + +  +   A KL   +KE+E++  
Sbjct: 762 EVEVAKLEKQLLE--EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHS 819

Query: 60  MFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETIST 119
             ++ ++++S+    ++ +K+N+  L+   K K+QE+  L    Q  +EE +  K    +
Sbjct: 820 EVVQIRSEVSQ----VKREKENIQTLL---KSKEQEVNELLQKFQQAQEELAEMKRYAES 872

Query: 120 ANKANAERLKRLQK 133
           ++K   ++ K++ +
Sbjct: 873 SSKLEEDKDKKINE 886


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 12/134 (8%)

Query: 3   EDELALFDKSINEFWNKFKSTDTSCQMAG---LRDTYKDSIKAFAEKLSVKLKEEERMVE 59
           E E+A  +K + E   K   TD     +    L+ + +  +   A KL   +KE+E++  
Sbjct: 762 EVEVAKLEKQLLE--EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHS 819

Query: 60  MFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETIST 119
             ++ ++++S+    ++ +K+N+  L+   K K+QE+  L    Q  +EE +  K    +
Sbjct: 820 EVVQIRSEVSQ----VKREKENIQTLL---KSKEQEVNELLQKFQQAQEELAEMKRYAES 872

Query: 120 ANKANAERLKRLQK 133
           ++K   ++ K++ +
Sbjct: 873 SSKLEEDKDKKINE 886


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 12/134 (8%)

Query: 3   EDELALFDKSINEFWNKFKSTDTSCQMAG---LRDTYKDSIKAFAEKLSVKLKEEERMVE 59
           E E+A  +K + E   K   TD     +    L+ + +  +   A KL   +KE+E++  
Sbjct: 762 EVEVAKLEKQLLE--EKAAMTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHS 819

Query: 60  MFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETIST 119
             ++ ++++S+    ++ +K+N+  L+   K K+QE+  L    Q  +EE +  K    +
Sbjct: 820 EVVQIRSEVSQ----VKREKENIQTLL---KSKEQEVNELLQKFQQAQEELAEMKRYAES 872

Query: 120 ANKANAERLKRLQK 133
           ++K   ++ K++ +
Sbjct: 873 SSKLEEDKDKKINE 886


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 48/222 (21%), Positives = 94/222 (42%), Gaps = 24/222 (10%)

Query: 3    EDELALFDKSINEFWNKFKSTDTSCQMAGLRDTYKDSI----KAFAEKLSVKLKEEERMV 58
            E +L    K +NE   K        +M  L+   KD      K   E L++  K  E + 
Sbjct: 1829 EHQLITLKKDVNETQKKVS------EMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLE 1882

Query: 59   EM--FLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKET 116
            EM   ++ ++ + R  + ++ ++D L + + E K +  E++      + L +E+   KET
Sbjct: 1883 EMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEH---KET 1939

Query: 117  ISTANKANAER---LKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFS 173
            +    +  +E+   +  +QK  D  KD L  +I+++  ++LQ +      +  E   M  
Sbjct: 1940 VDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLL------RVKEDVNMSH 1993

Query: 174  LHLNEARDYEVSDSAPHLEGLAEFQENVRKTNNFSAFLANVR 215
              +NE    +    A +L   +   +N + T      L  +R
Sbjct: 1994 KKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIR 2035



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 26/122 (21%), Positives = 54/122 (44%), Gaps = 6/122 (4%)

Query: 18  NKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQE 77
           + +KSTD   Q       +K     F +K  + L+E ERM +  +    +  + +  +  
Sbjct: 810 SNYKSTDQEFQ------NFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGA 863

Query: 78  KKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSADL 137
            K  L     E++ K +E++     ++ LKE+   +  T+ T  +      ++LQ++ + 
Sbjct: 864 LKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEE 923

Query: 138 YK 139
            K
Sbjct: 924 VK 925



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 28/116 (24%), Positives = 55/116 (47%), Gaps = 12/116 (10%)

Query: 47   LSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDL 106
            LS +L+E    ++   + ++ + R  +++Q + D L + I E+  K  E E      ++L
Sbjct: 1426 LSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETE------EEL 1479

Query: 107  KEEYSRKKETISTANKANAE------RLKRLQKSADLYKDRLGLEIRKIYGEKLQF 156
            K  +   KE   T N+           +  +QK  +   D+L  +I++IY ++ QF
Sbjct: 1480 KVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQF 1535



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 28/106 (26%), Positives = 52/106 (49%), Gaps = 1/106 (0%)

Query: 50   KLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEE 109
            KLKE+ + ++   +    +  +   +Q+K + +  L  E+K K+  LE +     +L ++
Sbjct: 1128 KLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQK 1187

Query: 110  YSRKKETISTANKANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQ 155
             +   E + +  K   + LK LQKS +  +D L   IR+I    LQ
Sbjct: 1188 LNENYEEVKSITK-ERKVLKELQKSFETERDHLRGYIREIEATGLQ 1232



 Score = 35.4 bits (80), Expect = 0.040
 Identities = 25/91 (27%), Positives = 48/91 (52%), Gaps = 5/91 (5%)

Query: 50  KLKEEERMVEMFLEYQNQISRQNKLIQE-KKDNLLKLIAEVKGKKQELEVLTANIQDLKE 108
           +L+ E+  +E+ L+ +N +     L ++ KKD  ++LI E+   K  ++      QDL+ 
Sbjct: 516 QLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLEN 575

Query: 109 EYSRKKETISTANKANAERLKRLQKSADLYK 139
           E S K E +    +   +++K+LQ+  D  K
Sbjct: 576 ELSSKVELL----REKEDQIKKLQEYIDSQK 602



 Score = 31.2 bits (69), Expect = 0.75
 Identities = 31/129 (24%), Positives = 62/129 (48%), Gaps = 29/129 (22%)

Query: 38   DSIKAFAEKLSVKLKEEERMVEMFLEYQ-------NQISRQNKLIQEKKDNLLKL----- 85
            +S+ A  E+L   LKE    +EM +E Q       +++ +Q +++ ++K++ +K      
Sbjct: 1060 ESVIAEKEQLKTDLKEN---IEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELS 1116

Query: 86   -----IAEV----KGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSAD 136
                 +AEV    K K Q+L+     + +++EE S  ++ I+       E LK   K+ +
Sbjct: 1117 RTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKIN-----EIENLKNELKNKE 1171

Query: 137  LYKDRLGLE 145
            L  + +  E
Sbjct: 1172 LTLEHMETE 1180



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 20/90 (22%), Positives = 39/90 (43%)

Query: 51  LKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEY 110
           L+EE  ++       +++ R  K IQ+K + L  + +E      E+    + +Q L EE 
Sbjct: 739 LREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEI 798

Query: 111 SRKKETISTANKANAERLKRLQKSADLYKD 140
            + K+ ++T         +  Q    L+ D
Sbjct: 799 GKTKDDLATTQSNYKSTDQEFQNFKTLHMD 828



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 12/131 (9%)

Query: 28  QMAGLRDTYK---DSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLK 84
           +M  L  TYK   + I+ +  +L  K K +  + +      N+I++   LI  K    L 
Sbjct: 654 KMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLL 713

Query: 85  LIAEVKGK----KQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSADLY-- 138
              E++GK    ++EL       + L+EE     E  S  ++    R +   KS +L+  
Sbjct: 714 CNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHII 773

Query: 139 ---KDRLGLEI 146
              KD+L  E+
Sbjct: 774 TSEKDKLFSEV 784


>gi|58530842 desmoplakin isoform II [Homo sapiens]
          Length = 2272

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 45/168 (26%), Positives = 81/168 (48%), Gaps = 25/168 (14%)

Query: 2    VEDELALFDKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEK------LSVKLKEEE 55
            VED    FD+  N++    K+    C+   L     +S KA  EK      L V L+EE 
Sbjct: 1128 VEDR---FDQQKNDYDQLQKARQ--CEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEG 1182

Query: 56   RMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVL---TANIQDLKEEYSR 112
                   EY+N++++ +  IQE K+   +++ E +    +++VL    A +Q L++E +R
Sbjct: 1183 TRKR---EYENELAKASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDELNR 1239

Query: 113  KKETISTANKANAERL----KRLQKSADLYKDRLGLE---IRKIYGEK 153
             K T+    +   +RL    +++Q   + +K +   +   IRKI  E+
Sbjct: 1240 AKSTLEAETRVK-QRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESER 1286



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 40/156 (25%), Positives = 66/156 (42%), Gaps = 27/156 (17%)

Query: 1    MVEDELALFDKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEM 60
            ++E+EL L   + +E  NK K  D + Q       Y+     F  KL+  L+E +R  E+
Sbjct: 1036 VLEEELRLARDANSENCNKNKFLDQNLQK------YQAECSQFKAKLA-SLEELKRQAEL 1088

Query: 61   FLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTA 120
              +               K NL K   ++K   +++  LT  I+D K    R+++++   
Sbjct: 1089 DGK-------------SAKQNLDKCYGQIKELNEKITRLTYEIEDEK----RRRKSVEDR 1131

Query: 121  NKANAERLKRLQKSADLYKDRLG---LEIRKIYGEK 153
                     +LQK+    K+ LG   LE  K   EK
Sbjct: 1132 FDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEK 1167


>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 47/204 (23%), Positives = 91/204 (44%), Gaps = 48/204 (23%)

Query: 45  EKLSVKLKEEER--------MVEMFLEYQNQISRQNKLIQEKKDNLLKLIA-------EV 89
           EKL+ +LKEEE+        +++   +Y+    ++ ++ +EK++ L++ +        E 
Sbjct: 513 EKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQVAEQEY 572

Query: 90  KGKKQELEVLT----------------------------ANIQDLKEEYSRKKETISTAN 121
           K K+++LE L+                            +N++D+K+E  + ++  S  N
Sbjct: 573 KEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQQLRDQESKKN 632

Query: 122 KANAERLKRLQKS---ADLYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFSLHLNE 178
           K + E LK L+      D   D L LE +K+  E + ++  NI+ K  E         N+
Sbjct: 633 KDHFETLKNLENGFYINDQKADLLLLENKKL-KEYILYLKNNIE-KYREGQEALMHTSND 690

Query: 179 ARDYEVSDSAPHLEGLAEFQENVR 202
                ++  A + +  AEFQ  V+
Sbjct: 691 LSRQLIAQEAQYKDLWAEFQTTVK 714


>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 45/204 (22%), Positives = 91/204 (44%), Gaps = 48/204 (23%)

Query: 45  EKLSVKLKEEER--------MVEMFLEYQNQISRQNKLIQEKKDNLLKLIA-------EV 89
           EKL+ +LKEEE+        +++   +Y+    ++ ++ +EK++ L++ +        E 
Sbjct: 513 EKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQVAEQEY 572

Query: 90  KGKKQELEVLT----------------------------ANIQDLKEEYSRKKETISTAN 121
           K K+++LE L+                            +N++D+K+E  + ++  S  N
Sbjct: 573 KEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQQLRDQESKKN 632

Query: 122 KANAERLKRLQKS---ADLYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFSLHLNE 178
           K + E LK L+      D   D L LE +K+  E + ++  NI+        +     + 
Sbjct: 633 KDHFETLKNLENGFYINDQKADLLLLENKKL-KEYILYLKNNIEKYREGQEALMHTSSDL 691

Query: 179 ARDYEVSDSAPHLEGLAEFQENVR 202
           +R   ++  A + +  AEFQ  V+
Sbjct: 692 SRQL-IAQEAQYKDLWAEFQTTVK 714


>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 45/204 (22%), Positives = 91/204 (44%), Gaps = 48/204 (23%)

Query: 45  EKLSVKLKEEER--------MVEMFLEYQNQISRQNKLIQEKKDNLLKLIA-------EV 89
           EKL+ +LKEEE+        +++   +Y+    ++ ++ +EK++ L++ +        E 
Sbjct: 513 EKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQVAEQEY 572

Query: 90  KGKKQELEVLT----------------------------ANIQDLKEEYSRKKETISTAN 121
           K K+++LE L+                            +N++D+K+E  + ++  S  N
Sbjct: 573 KEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQQLRDQESKKN 632

Query: 122 KANAERLKRLQKS---ADLYKDRLGLEIRKIYGEKLQFIFTNIDPKNPESPFMFSLHLNE 178
           K + E LK L+      D   D L LE +K+  E + ++  NI+        +     + 
Sbjct: 633 KDHFETLKNLENGFYINDQKADLLLLENKKL-KEYILYLKNNIEKYREGQEALMHTSSDL 691

Query: 179 ARDYEVSDSAPHLEGLAEFQENVR 202
           +R   ++  A + +  AEFQ  V+
Sbjct: 692 SRQL-IAQEAQYKDLWAEFQTTVK 714


>gi|13699824 kinesin family member 11 [Homo sapiens]
          Length = 1056

 Score = 40.4 bits (93), Expect = 0.001
 Identities = 29/139 (20%), Positives = 63/139 (45%), Gaps = 5/139 (3%)

Query: 29  MAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNL---LKL 85
           M+G     ++ I    EK+    +E  R+ E+F++ +N++ +    +Q K   L    K 
Sbjct: 408 MSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKH 467

Query: 86  IAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSADLYK--DRLG 143
           + E K +  + E +T+ ++  +E+       +    +   + +  L    D  K  D+  
Sbjct: 468 LQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHN 527

Query: 144 LEIRKIYGEKLQFIFTNID 162
            E + I+G+ L  +F N++
Sbjct: 528 AEAQDIFGKNLNSLFNNME 546


>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
            sapiens]
          Length = 1907

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 29/135 (21%), Positives = 65/135 (48%), Gaps = 15/135 (11%)

Query: 36   YKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKK-------DNLLKLIAE 88
            Y+ + +  +EKL   +KE   +V+    Y+ +I    K +QE +       D  +K   +
Sbjct: 1209 YQVTEQQISEKLKTIMKENTELVQKLSNYEQKIKESKKHVQETRKQNMILSDEAIKYKDK 1268

Query: 89   VKGKKQELEVLTANIQDLK------EEYSRKKETISTANKANAERLKRL--QKSADLYKD 140
            +K  ++  E+L    ++L+       E + K + + + NK + E+LK +    +++  + 
Sbjct: 1269 IKTLEKNQEILDDTAKNLRVMLESEREQNVKNQDLISENKKSIEKLKDVISMNASEFSEV 1328

Query: 141  RLGLEIRKIYGEKLQ 155
            ++ L   K+  EK++
Sbjct: 1329 QIALNEAKLSEEKVK 1343



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 30/126 (23%)

Query: 36   YKDSIKAF----------AEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKD----- 80
            YKD IK            A+ L V L+ E    E  ++ Q+ IS   K I++ KD     
Sbjct: 1265 YKDKIKTLEKNQEILDDTAKNLRVMLESER---EQNVKNQDLISENKKSIEKLKDVISMN 1321

Query: 81   -----------NLLKLIAE-VKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERL 128
                       N  KL  E VK +   ++   A ++  KE+  ++ E  S  +   +E++
Sbjct: 1322 ASEFSEVQIALNEAKLSEEKVKSECHRVQEENARLKKKKEQLQQEIEDWSKLHAELSEQI 1381

Query: 129  KRLQKS 134
            K  +KS
Sbjct: 1382 KSFEKS 1387


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 43/195 (22%), Positives = 88/195 (45%), Gaps = 7/195 (3%)

Query: 2    VEDELALFDKSINEFWNKFKS--TDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVE 59
            +E E  L  K + E   + K   T+       ++D  +   K  +E +  K+K   ++ E
Sbjct: 831  LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE-MEQKVKSLTQVYE 889

Query: 60   MFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETIST 119
              LE  N+   Q K I  +K+N++  + E  G+K+E+E+LT  +   ++      E   T
Sbjct: 890  SKLEDGNKEQEQTKQILVEKENMILQMRE--GQKKEIEILTQKLSAKEDSIHILNEEYET 947

Query: 120  ANKANAERLKRLQKSADLYKDRLGLEIRKIYGE-KLQFIFTNIDPKNPESPFMFS-LHLN 177
              K   ++++++++ A   ++ L  ++     + K +   T ++    E  F    L + 
Sbjct: 948  KFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMA 1007

Query: 178  EARDYEVSDSAPHLE 192
            +A    +SD+   LE
Sbjct: 1008 QANSAGISDAVSRLE 1022



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 26/115 (22%), Positives = 59/115 (51%), Gaps = 6/115 (5%)

Query: 34   DTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEK----KDNLLKLIAEV 89
            ++  + +K + ++  ++ KE  + ++ F E   +   + K  +EK    ++ +  + AE+
Sbjct: 1542 ESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAEL 1601

Query: 90   KGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRL--QKSADLYKDRL 142
            + KK+ELE +  +++  +EE    ++ + + + A    LKR   QK A + K  L
Sbjct: 1602 ETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLL 1656



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 38/210 (18%), Positives = 85/210 (40%), Gaps = 29/210 (13%)

Query: 10  DKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKE---------EERMVEM 60
           +KS+ E  NK +S D +  +   ++ +   I    EK   +L+           E++  +
Sbjct: 577 EKSLQE--NKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVL 634

Query: 61  FLEYQNQISRQNKLIQEKKDNLL----------------KLIAEVKGKKQELEVLTANIQ 104
             +YQ ++ +  +  +++K+ LL                K + ++  K+ ELE L++ + 
Sbjct: 635 KQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELS 694

Query: 105 DLKEEYSRKKETISTANKANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNIDPK 164
           ++ +   + +E +S       +  + L+   D  K+    ++  I  E  +      +  
Sbjct: 695 EVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEH-EVSIQRTEKA 753

Query: 165 NPESPFMFSLHLNEARDYEVSDSAPHLEGL 194
             +      L L E RD  + +   H+E L
Sbjct: 754 LKDQINQLELLLKE-RDKHLKEHQAHVENL 782



 Score = 32.3 bits (72), Expect = 0.34
 Identities = 30/127 (23%), Positives = 52/127 (40%), Gaps = 20/127 (15%)

Query: 10   DKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQIS 69
            D ++NE   + K            +T    +KA  EKL V L              N+  
Sbjct: 1105 DTTLNELQEQLKQKSAHVNSLAQDET---KLKAHLEKLEVDL--------------NKSL 1147

Query: 70   RQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLK 129
            ++N  +QE+   L  L  E K K  EL   T+ ++   EE+   K +   +NK+  ++  
Sbjct: 1148 KENTFLQEQLVELKMLAEEDKRKVSEL---TSKLKTTDEEFQSLKSSHEKSNKSLEDKSL 1204

Query: 130  RLQKSAD 136
              +K ++
Sbjct: 1205 EFKKLSE 1211



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 25/109 (22%), Positives = 50/109 (45%), Gaps = 5/109 (4%)

Query: 50   KLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAE----VKGKKQELEVLTANIQD 105
            +L+E+E  ++        +  + + +Q++  N  +  +E    +   K+EL      +  
Sbjct: 1298 QLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTL 1357

Query: 106  LKEEYSRKKETISTANKANAERLKRLQKSADLYKDRLGL-EIRKIYGEK 153
            +KEE   KK  IS+ +K   +   +LQ S  L +    +  +RK Y E+
Sbjct: 1358 MKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEE 1406



 Score = 27.7 bits (60), Expect = 8.3
 Identities = 28/108 (25%), Positives = 55/108 (50%), Gaps = 9/108 (8%)

Query: 28  QMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIA 87
           ++A LR   K  +    E+L  + ++ ER    F E +  +S   K  + ++    KL A
Sbjct: 383 EIAQLRSRIKQ-MTTQGEELREQKEKSERAA--FEELEKALSTAQKTEEARR----KLKA 435

Query: 88  EVKGKKQELEVLTANIQ-DLKEEYSR-KKETISTANKANAERLKRLQK 133
           E+  + + +E  +   +  L++E SR K+E +    K++ E++ +LQK
Sbjct: 436 EMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQK 483


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 30/117 (25%), Positives = 58/117 (49%), Gaps = 13/117 (11%)

Query: 38   DSIKAFAEKLSVKLKEEERMVEMF-------LEYQNQISRQNKLIQEKKDNLLKLIAEVK 90
            D +K+  E+L+  LK   +++E         L+Y NQ+ ++N+  Q K   L+K   +++
Sbjct: 2747 DLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLE 2806

Query: 91   GKKQELEVLTANIQDLKEE------YSRKKETISTANKANAERLKRLQKSADLYKDR 141
             +K+ L+   + +Q  +E+         K + ++T  K   E L+   K AD Y D+
Sbjct: 2807 EEKEILQKELSQLQAAQEKQKTGTVMDTKVDELTTEIKELKETLEEKTKEADEYLDK 2863



 Score = 35.8 bits (81), Expect = 0.030
 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 7/96 (7%)

Query: 38   DSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELE 97
            ++ KA  E L  +++E  R +++F             ++ +K+NL K I E +G+  EL+
Sbjct: 2178 ENSKAEVETLKTQIEEMARSLKVF-------ELDLVTLRSEKENLTKQIQEKQGQLSELD 2230

Query: 98   VLTANIQDLKEEYSRKKETISTANKANAERLKRLQK 133
             L ++ + L EE  + +  I   +K   E L+   K
Sbjct: 2231 KLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLK 2266



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 23/85 (27%), Positives = 43/85 (50%), Gaps = 7/85 (8%)

Query: 45   EKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQ 104
            EKL V+++ +E+      E   +  R+N  +++K +NL + + ++  + QEL +L A   
Sbjct: 2122 EKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLEREL-QMSEENQELVILDA--- 2177

Query: 105  DLKEEYSRKKETISTANKANAERLK 129
               E    + ET+ T  +  A  LK
Sbjct: 2178 ---ENSKAEVETLKTQIEEMARSLK 2199



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 75   IQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKS 134
            + E K+N + L + V G  QE+E     ++   EE SR K  I    +    +L +++  
Sbjct: 2489 LDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQL-VSKLSQVEGE 2547

Query: 135  ADLYKDRLGLEIRKIYGEKLQFI 157
              L+K++  LE+R +  E  Q I
Sbjct: 2548 HQLWKEQ-NLELRNLTVELEQKI 2569



 Score = 30.4 bits (67), Expect = 1.3
 Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 11/105 (10%)

Query: 42   AFAEKLS-VKLKEEERMVEMFLEYQNQISRQNKLIQEKK---DNLLKLIAEVKGKKQELE 97
            +F EK++ +  KE E   EM    Q     Q +L  EK      L  L+ E+K  K +L+
Sbjct: 2606 SFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLK 2665

Query: 98   VLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSADLYKDRL 142
             LT        E S  K+++   +K   E+  ++++    Y+ RL
Sbjct: 2666 ELTL-------ENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRL 2703



 Score = 30.0 bits (66), Expect = 1.7
 Identities = 20/72 (27%), Positives = 42/72 (58%), Gaps = 5/72 (6%)

Query: 75   IQEKKDNLLKLIAEVKGKKQELEVLTAN----IQDLKEEYSRKKETISTANKANAERLKR 130
            I+ +K+NL   + + + +  ELE++ ++    +Q+ ++E  + KE  STA +    +LK 
Sbjct: 2390 IRSEKENLTNELQKEQERISELEIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKE 2449

Query: 131  L-QKSADLYKDR 141
            L ++ A L+ D+
Sbjct: 2450 LNERVAALHNDQ 2461



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 11/112 (9%)

Query: 45   EKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTAN-- 102
            +K+ V L+EE  +V      +NQ+  +   + +K   L +L  ++K K QELE   +   
Sbjct: 1943 QKVIVCLEEELSVVT---SERNQLRGELDTMSKKTTALDQLSEKMKEKTQELESHQSECL 1999

Query: 103  --IQDLKEEYSRKKETISTANKANAERLK----RLQKSADLYKDRLGLEIRK 148
              IQ  + E   K E + T +   +E LK      +K   L KD   L + K
Sbjct: 2000 HCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTK 2051



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 30/139 (21%), Positives = 58/139 (41%), Gaps = 20/139 (14%)

Query: 5   ELALFDKSINEFWNKFKSTDTSCQMAGLRDT-YKDSIKAFAEKLSVKLKE--------EE 55
           EL   +K +N+  ++   T      A  + T  +  +K   E LS + +         E+
Sbjct: 328 ELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQ 387

Query: 56  RMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQ-----------ELEVLTANIQ 104
           ++ E   E+Q ++SRQ +  Q      +++ A +  + Q           EL+ LT+  Q
Sbjct: 388 KIKEKEKEFQEELSRQQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQ 447

Query: 105 DLKEEYSRKKETISTANKA 123
            L+      K+ +  A +A
Sbjct: 448 QLENNLEEFKQKLCRAEQA 466


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
            sapiens]
          Length = 1937

 Score = 39.3 bits (90), Expect = 0.003
 Identities = 33/138 (23%), Positives = 64/138 (46%), Gaps = 10/138 (7%)

Query: 9    FDKSINEFWNKFKSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQI 68
            FDK ++E+  K++ T      A L  + K+S       LS +L + + + E  L+    +
Sbjct: 1452 FDKVLSEWKQKYEETQ-----AELEASQKES-----RSLSTELFKVKNVYEESLDQLETL 1501

Query: 69   SRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERL 128
             R+NK +Q++  +L + IAE   +  ELE +   ++  K E     E    + +    ++
Sbjct: 1502 RRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKI 1561

Query: 129  KRLQKSADLYKDRLGLEI 146
             R+Q   +  K  +  +I
Sbjct: 1562 LRIQLELNQVKSEVDRKI 1579



 Score = 32.7 bits (73), Expect = 0.26
 Identities = 40/156 (25%), Positives = 74/156 (47%), Gaps = 23/156 (14%)

Query: 21  KSTDTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQN-QISRQNKL----- 74
           KS +T  +MA +++ ++ +    A+  + + + EE+MV +  E  + Q+  Q++      
Sbjct: 844 KSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLAD 903

Query: 75  IQEKKDNLLK-------LIAEVKGKKQELE----VLTANIQDLKEEYSRKKETIS----T 119
            +E+ + L+K        I EV  + +E E     LTA  + L++E S  K+ I     T
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963

Query: 120 ANKANAERLKRLQKSADLYKDRLGLE--IRKIYGEK 153
             K   E+     K  +L ++  GL+  I K+  EK
Sbjct: 964 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEK 999



 Score = 30.8 bits (68), Expect = 0.98
 Identities = 30/139 (21%), Positives = 59/139 (42%), Gaps = 18/139 (12%)

Query: 21   KSTDTSCQMAGLRDTYKDSIKAF------AEKLSVK--LKEEERMVEMFLEYQNQISRQN 72
            K  DTS  +  ++   + ++K        AE+L++K   K+ +++     E + ++  + 
Sbjct: 1774 KEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQ 1833

Query: 73   KLIQEKKDNLLKLIAEVKGKKQELEVLTANI---QDLKEE-------YSRKKETISTANK 122
            K   E    L K    VK    + E    N+   QDL ++       Y R+ E     + 
Sbjct: 1834 KRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1893

Query: 123  ANAERLKRLQKSADLYKDR 141
            AN  + ++LQ   +  ++R
Sbjct: 1894 ANLSKFRKLQHELEEAEER 1912



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 13/199 (6%)

Query: 32   LRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKG 91
            ++ T    I++  + L VK K E  + EM +    Q++  N+L  E   N       +K 
Sbjct: 1600 MQSTLDAEIRSRNDALRVKKKMEGDLNEMEI----QLNHANRLAAESLRNYRNTQGILKE 1655

Query: 92   KKQELEVLTANIQDLKEEYS---RKKETISTANK---ANAERLKRLQKSADLYKDRLGLE 145
             +  L+      +DLKE+ +   R+   +    +   A  E+ +R +K A+         
Sbjct: 1656 TQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASER 1715

Query: 146  IRKIYGEKLQFIFTNIDPKNPESPFMFSLH--LNEARDYEVSDSAPHLEGLAEFQENVRK 203
            ++ ++ +    I T    +N  S     +   + E+R+ E   +   +   A   E ++K
Sbjct: 1716 VQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAE-EKAKKAITDAAMMAEELKK 1774

Query: 204  TNNFSAFLANVRKAFTATV 222
              + SA L  ++K    TV
Sbjct: 1775 EQDTSAHLERMKKNLEQTV 1793


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 41/172 (23%), Positives = 76/172 (44%), Gaps = 10/172 (5%)

Query: 40   IKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVL 99
            +K    K+  +L+E ER  +  LE +N ++ Q +   E      ++ A +  KKQELE +
Sbjct: 864  VKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEI 923

Query: 100  TANIQDLKEEYSRKKETISTANKANAERLKRLQKSADLYKD-RLGLEIRKIYGE----KL 154
              +++   EE   + + +    K     ++ L++  D  +  R  L++ K+  E    K+
Sbjct: 924  LHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKM 983

Query: 155  QFIFTNIDPKNPESPFMFSLHLNEARDYEVSDSAPHLEGLAEFQENVRKTNN 206
            +     ++ +N  S F+    L E R  E S      E   E  +N+ K  N
Sbjct: 984  EEEILLLEDQN--SKFIKEKKLMEDRIAECSSQLAEEE---EKAKNLAKIRN 1030



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 4/95 (4%)

Query: 50   KLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLK----LIAEVKGKKQELEVLTANIQD 105
            KL+ E  M  M  +++  +  +++  +EKK  L+K    L AE++ ++++  +  A+ + 
Sbjct: 1562 KLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKK 1621

Query: 106  LKEEYSRKKETISTANKANAERLKRLQKSADLYKD 140
            ++ +    +  I  ANKA  E +K+L+K     KD
Sbjct: 1622 MEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD 1656



 Score = 34.7 bits (78), Expect = 0.068
 Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 14/109 (12%)

Query: 45   EKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGK-KQELEVLTANI 103
            + L+ +L  E    +     + Q+ RQNK   E K  L +L   VK K K  +  L A I
Sbjct: 1767 DTLNAELAAERSAAQKSDNARQQLERQNK---ELKAKLQELEGAVKSKFKATISALEAKI 1823

Query: 104  QDLKEEYSRKKETISTANKANAERLKRL----------QKSADLYKDRL 142
              L+E+  ++ +  + ANK      K+L          ++ AD YK+++
Sbjct: 1824 GQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQM 1872



 Score = 33.1 bits (74), Expect = 0.20
 Identities = 22/132 (16%), Positives = 62/132 (46%), Gaps = 10/132 (7%)

Query: 24   DTSCQMAGLRDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLL 83
            D S ++  L+   +D++   A +  ++ K E+ + E+    + +       IQ+ +    
Sbjct: 1143 DLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHA 1202

Query: 84   KLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAERLKRLQK---SADLYKD 140
              + E+  + ++ +   AN++       + K+ + T NK  A  +K LQ+    ++  + 
Sbjct: 1203 TALEELSEQLEQAKRFKANLE-------KNKQGLETDNKELACEVKVLQQVKAESEHKRK 1255

Query: 141  RLGLEIRKIYGE 152
            +L  ++++++ +
Sbjct: 1256 KLDAQVQELHAK 1267



 Score = 32.3 bits (72), Expect = 0.34
 Identities = 24/103 (23%), Positives = 44/103 (42%)

Query: 37   KDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQEL 96
            +D  +A A +   K     R +E  LE + +  RQNK ++   ++L+    +V     EL
Sbjct: 1471 RDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHEL 1530

Query: 97   EVLTANIQDLKEEYSRKKETISTANKANAERLKRLQKSADLYK 139
            E     ++   EE   + E +    +A  +   RL+ +    K
Sbjct: 1531 EKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK 1573



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 18/76 (23%), Positives = 35/76 (46%)

Query: 45   EKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQ 104
            EK     K   +   M  + + ++ ++ K  QE +    KL  E    + ++  L A I 
Sbjct: 1020 EKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQID 1079

Query: 105  DLKEEYSRKKETISTA 120
            +LK + ++K+E +  A
Sbjct: 1080 ELKLQLAKKEEELQGA 1095



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 4/81 (4%)

Query: 54   EERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRK 113
            E+   E+  E  N  S ++ L+ EK+    +L A +   ++ELE   +N++ L + + + 
Sbjct: 1707 EQERDELADEITNSASGKSALLDEKR----RLEARIAQLEEELEEEQSNMELLNDRFRKT 1762

Query: 114  KETISTANKANAERLKRLQKS 134
               + T N   A      QKS
Sbjct: 1763 TLQVDTLNAELAAERSAAQKS 1783



 Score = 28.9 bits (63), Expect = 3.7
 Identities = 26/115 (22%), Positives = 56/115 (48%), Gaps = 14/115 (12%)

Query: 37   KDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQEL 96
            ++ I    ++ S  +KE++ M +   E  +Q++ +    +EK  NL K+       + + 
Sbjct: 984  EEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE----EEKAKNLAKI-------RNKQ 1032

Query: 97   EVLTANIQD-LKEEYSRKKETISTANKANAERLKRLQKSADLYK--DRLGLEIRK 148
            EV+ +++++ LK+E   ++E      K + E      + A+L    D L L++ K
Sbjct: 1033 EVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAK 1087



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 18/60 (30%), Positives = 30/60 (50%)

Query: 67  QISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLKEEYSRKKETISTANKANAE 126
           Q++RQ + +Q K + LLK+  +    + ELE +    Q L EE +   E +    +  AE
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAE 905


>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
          Length = 514

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 36/140 (25%), Positives = 64/140 (45%), Gaps = 21/140 (15%)

Query: 41  KAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLT 100
           K   E++  KL EE+R+ +   E Q +  RQ +L++  +  L   I  +K ++Q  ++L 
Sbjct: 194 KLVEEQMFSKLWEEDRLAKEKREAQ-EARRQKELMENTRLGLNAQITSIKAQRQATQLLK 252

Query: 101 A----------------NIQDLKEEYSRKKETISTANKANAERLKRLQKSADLYKDRLGL 144
                            N QD+ ++   K+ET +   KA  ER++ +Q+    Y+D   L
Sbjct: 253 EEEARLVESNNAQIKHENEQDMLKKQKAKQETRTILQKALQERIEHIQQE---YRDEQDL 309

Query: 145 EIRKIYGEKLQFIFTNIDPK 164
            + K+    LQ +    D K
Sbjct: 310 NM-KLVQRALQDLQEEADKK 328


>gi|157671919 hypothetical protein LOC374864 isoform 1 [Homo
           sapiens]
          Length = 867

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 47/208 (22%), Positives = 86/208 (41%), Gaps = 27/208 (12%)

Query: 33  RDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGK 92
           +D Y+D     A K     +E  ++  +F  Y + +   N  I+EK++ + + I E K  
Sbjct: 328 KDIYQDEKTIEAYK-----REIYQLNSLFDHYSSSVINVNTNIEEKEEEVTEAIRETKSS 382

Query: 93  KQELEVLTANIQDLKEEY--------SRKKETISTANKANAERLKRLQKSADLYKD--RL 142
           K EL  L+  ++DL+  Y        S + + +   N   A +     + +D+ KD   +
Sbjct: 383 KNELHSLSKMLEDLRRVYDQLTWKQKSHENQYLEAVNDFYAAKKTWDIELSDVAKDFSAI 442

Query: 143 GLEIRKIY--GEKLQFIFTNIDPKNPESPFMFSLHLNEARDYEVS--DSAPHLEGLAE-- 196
            L   K+    +KL+     I  K  ES    S + +E +   +    +  HL+ + +  
Sbjct: 443 SLACTKLTEDNKKLEIDINKITVKTNESIRKKSKYESEIKYLTIMKLKNDKHLKNIYKEA 502

Query: 197 ------FQENVRKTNNFSAFLANVRKAF 218
                 F     KT+     +A VR+ F
Sbjct: 503 YRIGTLFHLTKHKTDEMEDKIAEVRRKF 530



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 43/194 (22%), Positives = 80/194 (41%), Gaps = 39/194 (20%)

Query: 52  KEEERMVEMFLEYQ-------NQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTAN-- 102
           KE E  +   +E Q       NQ+    K   E ++   K+ A++    +   +L +   
Sbjct: 219 KEHEAYLSDVIELQWHLEDKANQLQHFEKQKTELEEANAKIQADIDYMNEHGPLLDSKQN 278

Query: 103 --IQDLKEEYSRKKETISTANKANAE-----------RLKRLQ----KSADLYKDRLGLE 145
             +QDLK  Y +K E +    K N E           RLK  Q       D+Y+D   +E
Sbjct: 279 QELQDLKNHYKKKMEVMDLHRKVNEELEEALEACENARLKAQQIKEEIDKDIYQDEKTIE 338

Query: 146 IRKIYGEKLQFIFTNIDPKNPESPFMFSLHLN-EARDYEVSDSAPHLEGLAEFQENVRKT 204
             K    +L  +F +       S  + +++ N E ++ EV+      E + E + +  + 
Sbjct: 339 AYKREIYQLNSLFDHY------SSSVINVNTNIEEKEEEVT------EAIRETKSSKNEL 386

Query: 205 NNFSAFLANVRKAF 218
           ++ S  L ++R+ +
Sbjct: 387 HSLSKMLEDLRRVY 400


>gi|157671917 hypothetical protein LOC374864 isoform 2 [Homo
           sapiens]
          Length = 829

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 47/208 (22%), Positives = 86/208 (41%), Gaps = 27/208 (12%)

Query: 33  RDTYKDSIKAFAEKLSVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGK 92
           +D Y+D     A K     +E  ++  +F  Y + +   N  I+EK++ + + I E K  
Sbjct: 328 KDIYQDEKTIEAYK-----REIYQLNSLFDHYSSSVINVNTNIEEKEEEVTEAIRETKSS 382

Query: 93  KQELEVLTANIQDLKEEY--------SRKKETISTANKANAERLKRLQKSADLYKD--RL 142
           K EL  L+  ++DL+  Y        S + + +   N   A +     + +D+ KD   +
Sbjct: 383 KNELHSLSKMLEDLRRVYDQLTWKQKSHENQYLEAVNDFYAAKKTWDIELSDVAKDFSAI 442

Query: 143 GLEIRKIY--GEKLQFIFTNIDPKNPESPFMFSLHLNEARDYEVS--DSAPHLEGLAE-- 196
            L   K+    +KL+     I  K  ES    S + +E +   +    +  HL+ + +  
Sbjct: 443 SLACTKLTEDNKKLEIDINKITVKTNESIRKKSKYESEIKYLTIMKLKNDKHLKNIYKEA 502

Query: 197 ------FQENVRKTNNFSAFLANVRKAF 218
                 F     KT+     +A VR+ F
Sbjct: 503 YRIGTLFHLTKHKTDEMEDKIAEVRRKF 530



 Score = 31.6 bits (70), Expect = 0.57
 Identities = 43/194 (22%), Positives = 80/194 (41%), Gaps = 39/194 (20%)

Query: 52  KEEERMVEMFLEYQ-------NQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTAN-- 102
           KE E  +   +E Q       NQ+    K   E ++   K+ A++    +   +L +   
Sbjct: 219 KEHEAYLSDVIELQWHLEDKANQLQHFEKQKTELEEANAKIQADIDYMNEHGPLLDSKQN 278

Query: 103 --IQDLKEEYSRKKETISTANKANAE-----------RLKRLQ----KSADLYKDRLGLE 145
             +QDLK  Y +K E +    K N E           RLK  Q       D+Y+D   +E
Sbjct: 279 QELQDLKNHYKKKMEVMDLHRKVNEELEEALEACENARLKAQQIKEEIDKDIYQDEKTIE 338

Query: 146 IRKIYGEKLQFIFTNIDPKNPESPFMFSLHLN-EARDYEVSDSAPHLEGLAEFQENVRKT 204
             K    +L  +F +       S  + +++ N E ++ EV+      E + E + +  + 
Sbjct: 339 AYKREIYQLNSLFDHY------SSSVINVNTNIEEKEEEVT------EAIRETKSSKNEL 386

Query: 205 NNFSAFLANVRKAF 218
           ++ S  L ++R+ +
Sbjct: 387 HSLSKMLEDLRRVY 400


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 17/184 (9%)

Query: 48  SVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLK 107
           S +LK+ E   E     ++ + R   L   +K   +KL   ++ K QELEV+    + L+
Sbjct: 223 SYQLKQLE---EQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQ 279

Query: 108 EEYSRKKETISTANK-----ANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNID 162
           EE S+ + TI    +       AE +  +    +L  +    E+R+  G+        ++
Sbjct: 280 EELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGD--LEAMNEMN 337

Query: 163 PKNPESPFMFSLHLNEARDY---EVSDSAPHLEG----LAEFQENVRKTNNFSAFLANVR 215
            +  E+     L L E  D     V ++   +E     +A++Q+ ++K    +A L +V 
Sbjct: 338 DELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVN 397

Query: 216 KAFT 219
           +  T
Sbjct: 398 RELT 401


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 17/184 (9%)

Query: 48  SVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLK 107
           S +LK+ E   E     ++ + R   L   +K   +KL   ++ K QELEV+    + L+
Sbjct: 337 SYQLKQLE---EQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQ 393

Query: 108 EEYSRKKETISTANK-----ANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNID 162
           EE S+ + TI    +       AE +  +    +L  +    E+R+  G+        ++
Sbjct: 394 EELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGD--LEAMNEMN 451

Query: 163 PKNPESPFMFSLHLNEARDY---EVSDSAPHLEG----LAEFQENVRKTNNFSAFLANVR 215
            +  E+     L L E  D     V ++   +E     +A++Q+ ++K    +A L +V 
Sbjct: 452 DELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVN 511

Query: 216 KAFT 219
           +  T
Sbjct: 512 RELT 515


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 17/184 (9%)

Query: 48  SVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLK 107
           S +LK+ E   E     ++ + R   L   +K   +KL   ++ K QELEV+    + L+
Sbjct: 223 SYQLKQLE---EQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQ 279

Query: 108 EEYSRKKETISTANK-----ANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNID 162
           EE S+ + TI    +       AE +  +    +L  +    E+R+  G+        ++
Sbjct: 280 EELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGD--LEAMNEMN 337

Query: 163 PKNPESPFMFSLHLNEARDY---EVSDSAPHLEG----LAEFQENVRKTNNFSAFLANVR 215
            +  E+     L L E  D     V ++   +E     +A++Q+ ++K    +A L +V 
Sbjct: 338 DELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVN 397

Query: 216 KAFT 219
           +  T
Sbjct: 398 RELT 401


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 17/184 (9%)

Query: 48  SVKLKEEERMVEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVLTANIQDLK 107
           S +LK+ E   E     ++ + R   L   +K   +KL   ++ K QELEV+    + L+
Sbjct: 357 SYQLKQLE---EQNARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQ 413

Query: 108 EEYSRKKETISTANK-----ANAERLKRLQKSADLYKDRLGLEIRKIYGEKLQFIFTNID 162
           EE S+ + TI    +       AE +  +    +L  +    E+R+  G+        ++
Sbjct: 414 EELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGD--LEAMNEMN 471

Query: 163 PKNPESPFMFSLHLNEARDY---EVSDSAPHLEG----LAEFQENVRKTNNFSAFLANVR 215
            +  E+     L L E  D     V ++   +E     +A++Q+ ++K    +A L +V 
Sbjct: 472 DELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAHLQDVN 531

Query: 216 KAFT 219
           +  T
Sbjct: 532 RELT 535


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 53/241 (21%), Positives = 100/241 (41%), Gaps = 35/241 (14%)

Query: 2   VEDELALFDKSINEFWNKFKSTDTSC-QMAGLRDTYKDSIKAFAEKLS---VKLKEEERM 57
           +E+E  +    I++  ++ KS    C Q+  L+      ++    +LS   + + + E  
Sbjct: 580 IEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAK 639

Query: 58  VEMFLEYQNQISRQNKLIQEKKDNLLKLIAEVKGKKQELEVL-------TANIQDLKEEY 110
           +    EY   +  + + ++E  D+L   +A+++ ++   EV        T +  ++K+  
Sbjct: 640 IRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKAL 699

Query: 111 SRKKETISTANKANAERLK----RLQKSADLYKD---RLGLEIRKIYG--EKLQFIFTNI 161
             + E+   A+     RL+      QK+ D  KD   +L LE+ K+    EKL+      
Sbjct: 700 ELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEK 759

Query: 162 DPKNPESPFMFSLHLNEARDYEVSDSAPHLEGLAEFQENVRKTNNFSAFLANVRKAFTAT 221
             K  E  F++  H    +D         L+GL E      +T      L N+RK F   
Sbjct: 760 STKLQELTFLYERHEQSKQD---------LKGLEETVARELQT------LHNLRKLFVQD 804

Query: 222 V 222
           V
Sbjct: 805 V 805


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,986,560
Number of Sequences: 37866
Number of extensions: 285962
Number of successful extensions: 2963
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 314
Number of HSP's that attempted gapping in prelim test: 1899
Number of HSP's gapped (non-prelim): 1286
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.