Guide to the Human Genome
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Search of human proteins with 18254464

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18254464 relaxin 3 preproprotein [Homo sapiens]
         (142 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18254464 relaxin 3 preproprotein [Homo sapiens]                    297   2e-81
gi|38569233 insulin-like 5 precursor [Homo sapiens]                    49   1e-06
gi|5902052 relaxin 1 preproprotein [Homo sapiens]                      37   0.004
gi|20143933 relaxin 2 isoform 1 preproprotein [Homo sapiens]           37   0.006
gi|20143935 relaxin 2 isoform 2 [Homo sapiens]                         35   0.027
gi|38327535 insulin-like 3 precursor [Homo sapiens]                    34   0.047
gi|239753791 PREDICTED: hypothetical protein [Homo sapiens]            30   0.88 
gi|91105174 CD19 antigen [Homo sapiens]                                29   1.1  
gi|169164409 PREDICTED: hypothetical protein [Homo sapiens]            28   2.0  
gi|113414195 PREDICTED: hypothetical protein [Homo sapiens]            28   2.0  
gi|113413381 PREDICTED: hypothetical protein [Homo sapiens]            28   2.0  
gi|38569396 insulin-like 6 precursor [Homo sapiens]                    28   2.6  
gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens]     27   4.4  
gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens]     27   4.4  
gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]      27   4.4  
gi|20336724 zinc finger protein 333 [Homo sapiens]                     27   4.4  
gi|4557671 proinsulin precursor [Homo sapiens]                         27   5.7  
gi|239757486 PREDICTED: hypothetical protein [Homo sapiens]            27   5.7  
gi|239752001 PREDICTED: hypothetical protein XP_002348063 [Homo ...    27   5.7  
gi|239746486 PREDICTED: hypothetical protein XP_002343772 [Homo ...    27   5.7  
gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens]      27   5.7  
gi|38016947 complement component 5 preproprotein [Homo sapiens]        27   7.4  
gi|239756307 PREDICTED: similar to ubiquitin-associated protein ...    26   9.7  
gi|239750857 PREDICTED: similar to ubiquitin-associated protein ...    26   9.7  
gi|239745220 PREDICTED: hypothetical protein [Homo sapiens]            26   9.7  

>gi|18254464 relaxin 3 preproprotein [Homo sapiens]
          Length = 142

 Score =  297 bits (760), Expect = 2e-81
 Identities = 142/142 (100%), Positives = 142/142 (100%)

Query: 1   MARYMLLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSDILAH 60
           MARYMLLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSDILAH
Sbjct: 1   MARYMLLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSDILAH 60

Query: 61  EAMGDTFPDADADEDSLAGELDEAMGSSEWLALTKSPQAFYRGRPSWQGTPGVLRGSRDV 120
           EAMGDTFPDADADEDSLAGELDEAMGSSEWLALTKSPQAFYRGRPSWQGTPGVLRGSRDV
Sbjct: 61  EAMGDTFPDADADEDSLAGELDEAMGSSEWLALTKSPQAFYRGRPSWQGTPGVLRGSRDV 120

Query: 121 LAGLSSSCCKWGCSKSEISSLC 142
           LAGLSSSCCKWGCSKSEISSLC
Sbjct: 121 LAGLSSSCCKWGCSKSEISSLC 142


>gi|38569233 insulin-like 5 precursor [Homo sapiens]
          Length = 135

 Score = 49.3 bits (116), Expect = 1e-06
 Identities = 36/118 (30%), Positives = 51/118 (43%), Gaps = 15/118 (12%)

Query: 32  VRLCGREFIRAVIFTCGGSRWRRSDILAHEAMGDTFPDADADEDSLAGELDEAMGSSEWL 91
           VRLCG E+IR VI+ C  SRWRR          +  P A   E   + +L      SE  
Sbjct: 26  VRLCGLEYIRTVIYICASSRWRRHQ--------EGIPQAQQAETGNSFQLPHKREFSEEN 77

Query: 92  ALTKSPQAFYRGRPS-WQG---TPGVLRGSRDVLAG---LSSSCCKWGCSKSEISSLC 142
                P+    G    W G   T  + +  +  +     L + CC  GCS +++S+LC
Sbjct: 78  PAQNLPKVDASGEDRLWGGQMPTEELWKSKKHSVMSRQDLQTLCCTDGCSMTDLSALC 135


>gi|5902052 relaxin 1 preproprotein [Homo sapiens]
          Length = 185

 Score = 37.4 bits (85), Expect = 0.004
 Identities = 22/71 (30%), Positives = 32/71 (45%)

Query: 1  MARYMLLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSDILAH 60
          M R  L  LL   +L  +      A+     ++LCGRE +RA I  CG S W +  +   
Sbjct: 1  MPRLFLFHLLEFCLLLNQFSRAVAAKWKDDVIKLCGRELVRAQIAICGMSTWSKRSLSQE 60

Query: 61 EAMGDTFPDAD 71
          +A     P A+
Sbjct: 61 DAPQTPRPVAE 71


>gi|20143933 relaxin 2 isoform 1 preproprotein [Homo sapiens]
          Length = 185

 Score = 37.0 bits (84), Expect = 0.006
 Identities = 42/185 (22%), Positives = 64/185 (34%), Gaps = 43/185 (23%)

Query: 1   MARYMLLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSDILAH 60
           M R     LL V +L  +             ++LCGRE +RA I  CG S W +  +   
Sbjct: 1   MPRLFFFHLLGVCLLLNQFSRAVADSWMEEVIKLCGRELVRAQIAICGMSTWSKRSLSQE 60

Query: 61  EAMGDTFPDADADEDSLAGELDEAMGSSEWLA-------LTKS------PQ--------- 98
           +A     P A+     +  + +     SE++A       LT S      PQ         
Sbjct: 61  DAPQTPRPVAEIVPSFINKDTETINMMSEFVANLPQELKLTLSEMQPALPQLQQHVPVLK 120

Query: 99  ----------AFYRGRPS-----------WQGTPGVLRGSRDVLAGLSSSCCKWGCSKSE 137
                        R R S           + G     R  R + + L++ CC  GC+K  
Sbjct: 121 DSSLLFEEFKKLIRNRQSEAADSSPSELKYLGLDTHSRKKRQLYSALANKCCHVGCTKRS 180

Query: 138 ISSLC 142
           ++  C
Sbjct: 181 LARFC 185


>gi|20143935 relaxin 2 isoform 2 [Homo sapiens]
          Length = 117

 Score = 34.7 bits (78), Expect = 0.027
 Identities = 19/62 (30%), Positives = 27/62 (43%)

Query: 1  MARYMLLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSDILAH 60
          M R     LL V +L  +             ++LCGRE +RA I  CG S W +  +   
Sbjct: 1  MPRLFFFHLLGVCLLLNQFSRAVADSWMEEVIKLCGRELVRAQIAICGMSTWSKRSLSQE 60

Query: 61 EA 62
          +A
Sbjct: 61 DA 62


>gi|38327535 insulin-like 3 precursor [Homo sapiens]
          Length = 131

 Score = 33.9 bits (76), Expect = 0.047
 Identities = 11/20 (55%), Positives = 15/20 (75%)

Query: 33 RLCGREFIRAVIFTCGGSRW 52
          +LCG  F+RA++  CGG RW
Sbjct: 32 KLCGHHFVRALVRVCGGPRW 51


>gi|239753791 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score = 29.6 bits (65), Expect = 0.88
 Identities = 20/46 (43%), Positives = 24/46 (52%), Gaps = 12/46 (26%)

Query: 94  TKSPQAFYRGRPS--WQGTPGVLRGSRDVLAGLSSSCCKWGCSKSE 137
           T++ Q F  G P   W+GTPGVL G         +SC   GCS SE
Sbjct: 3   TRTGQQF-PGHPEFPWRGTPGVLGG---------TSCRTRGCSSSE 38


>gi|91105174 CD19 antigen [Homo sapiens]
          Length = 556

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 15/40 (37%), Positives = 21/40 (52%)

Query: 68  PDADADEDSLAGELDEAMGSSEWLALTKSPQAFYRGRPSW 107
           P  D+   SL+ +L  A GS+ WL+    P +  RG  SW
Sbjct: 175 PPRDSLNQSLSQDLTMAPGSTLWLSCGVPPDSVSRGPLSW 214


>gi|169164409 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 120

 Score = 28.5 bits (62), Expect = 2.0
 Identities = 13/31 (41%), Positives = 17/31 (54%)

Query: 62 AMGDTFPDADADEDSLAGELDEAMGSSEWLA 92
          A GDT P A   +DS +     A GSS W++
Sbjct: 38 AQGDTSPGAGIGQDSRSTHARAAAGSSHWIS 68


>gi|113414195 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 120

 Score = 28.5 bits (62), Expect = 2.0
 Identities = 13/31 (41%), Positives = 17/31 (54%)

Query: 62 AMGDTFPDADADEDSLAGELDEAMGSSEWLA 92
          A GDT P A   +DS +     A GSS W++
Sbjct: 38 AQGDTSPGAGIGQDSRSTHARAAAGSSHWIS 68


>gi|113413381 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 120

 Score = 28.5 bits (62), Expect = 2.0
 Identities = 13/31 (41%), Positives = 17/31 (54%)

Query: 62 AMGDTFPDADADEDSLAGELDEAMGSSEWLA 92
          A GDT P A   +DS +     A GSS W++
Sbjct: 38 AQGDTSPGAGIGQDSRSTHARAAAGSSHWIS 68


>gi|38569396 insulin-like 6 precursor [Homo sapiens]
          Length = 213

 Score = 28.1 bits (61), Expect = 2.6
 Identities = 10/20 (50%), Positives = 12/20 (60%)

Query: 123 GLSSSCCKWGCSKSEISSLC 142
           G S  CC  GC+K E+S  C
Sbjct: 173 GYSEKCCLTGCTKEELSIAC 192


>gi|109134330 PHD finger protein 20-like 1 isoform 2 [Homo sapiens]
          Length = 573

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 10/22 (45%), Positives = 16/22 (72%)

Query: 78  AGELDEAMGSSEWLALTKSPQA 99
           AG  +++MGS +W+AL K+  A
Sbjct: 159 AGSCNQSMGSEDWIALVKAAAA 180


>gi|111120331 PHD finger protein 20-like 1 isoform 1 [Homo sapiens]
          Length = 1017

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 10/22 (45%), Positives = 16/22 (72%)

Query: 78  AGELDEAMGSSEWLALTKSPQA 99
           AG  +++MGS +W+AL K+  A
Sbjct: 159 AGSCNQSMGSEDWIALVKAAAA 180


>gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]
          Length = 677

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 17/52 (32%), Positives = 24/52 (46%), Gaps = 5/52 (9%)

Query: 87  SSEWLALTKSPQAFYRGRPSWQGTPGVLRGSRDVLAGLSSSCCKWGCSKSEI 138
           +S  L +  +  +F  G PS  G P + R S DVL     S CK   S+  +
Sbjct: 558 TSSQLMMNGATSSFENGHPSQPGPPQLTRASADVL-----SKCKKALSEHNV 604


>gi|20336724 zinc finger protein 333 [Homo sapiens]
          Length = 665

 Score = 27.3 bits (59), Expect = 4.4
 Identities = 13/51 (25%), Positives = 22/51 (43%)

Query: 52  WRRSDILAHEAMGDTFPDADADEDSLAGELDEAMGSSEWLALTKSPQAFYR 102
           W + D +  EAM    P A + E     ++       EW+ L  + ++ YR
Sbjct: 179 WLQEDKVEEEAMAPGLPTACSQEPVTFADVAVVFTPEEWVFLDSTQRSLYR 229


>gi|4557671 proinsulin precursor [Homo sapiens]
          Length = 110

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 15/43 (34%), Positives = 19/43 (44%), Gaps = 8/43 (18%)

Query: 6  LLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCG 48
          LL LLA+W        G +  AA     LCG   + A+   CG
Sbjct: 10 LLALLALW--------GPDPAAAFVNQHLCGSHLVEALYLVCG 44


>gi|239757486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 271

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 14/35 (40%), Positives = 17/35 (48%)

Query: 21  PGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRS 55
           PG E R  P   R   ++  R     CGG RWRR+
Sbjct: 178 PGVEWRRRPDRQRGKNQDVCRFREMGCGGVRWRRT 212


>gi|239752001 PREDICTED: hypothetical protein XP_002348063 [Homo
           sapiens]
          Length = 271

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 14/35 (40%), Positives = 17/35 (48%)

Query: 21  PGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRS 55
           PG E R  P   R   ++  R     CGG RWRR+
Sbjct: 178 PGVEWRRRPDRQRGKNQDVCRFREMGCGGVRWRRT 212


>gi|239746486 PREDICTED: hypothetical protein XP_002343772 [Homo
           sapiens]
          Length = 271

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 14/35 (40%), Positives = 17/35 (48%)

Query: 21  PGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRS 55
           PG E R  P   R   ++  R     CGG RWRR+
Sbjct: 178 PGVEWRRRPDRQRGKNQDVCRFREMGCGGVRWRRT 212


>gi|109148522 insulin- insulin-like growth factor 2 [Homo sapiens]
          Length = 200

 Score = 26.9 bits (58), Expect = 5.7
 Identities = 15/43 (34%), Positives = 19/43 (44%), Gaps = 8/43 (18%)

Query: 6  LLLLLAVWVLTGELWPGAEARAAPYGVRLCGREFIRAVIFTCG 48
          LL LLA+W        G +  AA     LCG   + A+   CG
Sbjct: 10 LLALLALW--------GPDPAAAFVNQHLCGSHLVEALYLVCG 44


>gi|38016947 complement component 5 preproprotein [Homo sapiens]
          Length = 1676

 Score = 26.6 bits (57), Expect = 7.4
 Identities = 18/54 (33%), Positives = 22/54 (40%), Gaps = 10/54 (18%)

Query: 68  PDADADEDSLAGELDEAMGSSEWLALTKSPQAFYRGRPSWQGTPGVLRGSRDVL 121
           PDADA        L+ A G   W+AL     A Y          GV RG++  L
Sbjct: 577 PDADAYSPGQTVSLNMATGMDSWVALAAVDSAVY----------GVQRGAKKPL 620


>gi|239756307 PREDICTED: similar to ubiquitin-associated protein 1
           (predicted) [Homo sapiens]
          Length = 290

 Score = 26.2 bits (56), Expect = 9.7
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 19  LWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSD 56
           L PG+ A   P G RLC  + +R V     G+R R S+
Sbjct: 128 LQPGSPASPGP-GRRLCSLDVLRGVRLELAGARRRLSE 164


>gi|239750857 PREDICTED: similar to ubiquitin-associated protein 1
           (predicted) [Homo sapiens]
          Length = 290

 Score = 26.2 bits (56), Expect = 9.7
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 19  LWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSD 56
           L PG+ A   P G RLC  + +R V     G+R R S+
Sbjct: 128 LQPGSPASPGP-GRRLCSLDVLRGVRLELAGARRRLSE 164


>gi|239745220 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 26.2 bits (56), Expect = 9.7
 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 19  LWPGAEARAAPYGVRLCGREFIRAVIFTCGGSRWRRSD 56
           L PG+ A   P G RLC  + +R V     G+R R S+
Sbjct: 128 LQPGSPASPGP-GRRLCSLDVLRGVRLELAGARRRLSE 164


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,982,789
Number of Sequences: 37866
Number of extensions: 264861
Number of successful extensions: 835
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 811
Number of HSP's gapped (non-prelim): 29
length of query: 142
length of database: 18,247,518
effective HSP length: 92
effective length of query: 50
effective length of database: 14,763,846
effective search space: 738192300
effective search space used: 738192300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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