Guide to the Human Genome
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Name: INS Sequence: fasta or formatted (110aa) NCBI GI: 4557671
Description:

proinsulin precursor

Referenced in:

Pancreas and Insulin
Receptor Tyrosine Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.1         10           3
 C cysteine            5.5          6           2
 D aspartate           1.8          2           1
 E glutamate           7.3          8           1
 F phenylalanine       2.7          3           2
 G glycine            10.9         12           3
 H histidine           1.8          2           1
 I isoleucine          1.8          2           1
 K lysine              1.8          2           1
 L leucine            18.2         20           2
 M methionine          1.8          2           1
 N asparagine          2.7          3           1
 P proline             5.5          6           1
 Q glutamine           6.4          7           1
 R arginine            4.5          5           2
 S serine              4.5          5           1
 T threonine           2.7          3           1
 V valine              5.5          6           1
 W tryptophan          1.8          2           1
 Y tyrosine            3.6          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   proinsulin precursor 
INS-IGF2              0.529   insulin- insulin-like growth factor 2 
IGF2                  0.131   insulin-like growth factor 2 isoform 1 precursor [Hom...
IGF2                  0.131   insulin-like growth factor 2 isoform 1 precursor [H...
IGF2                  0.131   insulin-like growth factor 2 isoform 2 
IGF1                  0.117   insulin-like growth factor 1 isoform 4 preproprotein...
IGF1                  0.117   insulin-like growth factor 1 isoform 3 preproprotei...
IGF1                  0.117   insulin-like growth factor 1 isoform 2 preproprotei...
IGF1                  0.117   insulin-like growth factor 1 isoform 1 preproprotei...
INSL3                 0.034   insulin-like 3 precursor 
TMPRSS3               0.024   transmembrane protease, serine 3 isoform 1 
TMPRSS3               0.024   transmembrane protease, serine 3 isoform 3 
TMPRSS13              0.019   transmembrane protease, serine 13 
WDR6                  0.015   WD repeat domain 6 protein 
PCDHAC2               0.015   protocadherin alpha subfamily C, 2 isoform 1 precurso...
PCDHAC2               0.015   protocadherin alpha subfamily C, 2 isoform 2 precurs...
WDR7                  0.010   rabconnectin-3 beta isoform 2 
WDR7                  0.010   rabconnectin-3 beta isoform 1 
C7orf27               0.010   hypothetical protein LOC221927 
RLN3                  0.010   relaxin 3 preproprotein 
RNF31                 0.005   ring finger protein 31 
PLXNB1                0.005   plexin B1 
PLXNB1                0.005   plexin B1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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