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Search of human proteins with 18104962
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|18104962 amyloid beta precursor protein-binding protein 2
[Homo sapiens]
(585 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|18104962 amyloid beta precursor protein-binding protein 2 [Ho... 1178 0.0
gi|34304360 nephrocystin 3 [Homo sapiens] 69 9e-12
gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens] 61 3e-09
gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens] 61 3e-09
gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens] 61 3e-09
gi|91825557 kinesin light chain 3 [Homo sapiens] 57 5e-08
gi|41871960 kinesin-like 8 isoform b [Homo sapiens] 55 1e-07
gi|41871955 kinesin-like 8 isoform a [Homo sapiens] 55 1e-07
gi|41871946 kinesin-like 8 isoform a [Homo sapiens] 55 1e-07
gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens] 55 2e-07
gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens] 55 2e-07
gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens] 55 2e-07
gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens] 55 2e-07
gi|87162455 hypothetical protein LOC23277 [Homo sapiens] 44 3e-04
gi|224809432 transmembrane and tetratricopeptide repeat containi... 41 0.003
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 39 0.017
gi|22749211 transmembrane and tetratricopeptide repeat containin... 35 0.19
gi|83415184 transmembrane and tetratricopeptide repeat containin... 35 0.25
gi|224548927 G-protein signaling modulator 1 (AGS3-like, C. eleg... 33 0.95
gi|224548925 G-protein signaling modulator 1 (AGS3-like, C. eleg... 33 0.95
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 32 1.6
gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens] 32 1.6
gi|7657265 fem-1 homolog b [Homo sapiens] 32 2.1
gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens] 32 2.1
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ... 31 2.8
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ... 31 2.8
gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo ... 31 2.8
gi|21686971 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-ace... 31 2.8
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 31 3.6
gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens] 30 4.7
>gi|18104962 amyloid beta precursor protein-binding protein 2 [Homo
sapiens]
Length = 585
Score = 1178 bits (3048), Expect = 0.0
Identities = 585/585 (100%), Positives = 585/585 (100%)
Query: 1 MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEF 60
MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEF
Sbjct: 1 MAAVELEWIPETLYNTAISAVVDNYIRSRRDIRSLPENIQFDVYYKLYQQGRLCQLGSEF 60
Query: 61 CELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAI 120
CELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAI
Sbjct: 61 CELEVFAKVLRALDKRHLLHHCFQALMDHGVKVASVLAYSFSRRCSYIAESDAAVKEKAI 120
Query: 121 QVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYH 180
QVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYH
Sbjct: 121 QVGFVLGGFLSDAGWYSDAEKVFLSCLQLCTLHDEMLHWFRAVECCVRLLHVRNGNCKYH 180
Query: 181 LGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGL 240
LGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGL
Sbjct: 181 LGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGL 240
Query: 241 PVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLN 300
PVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLN
Sbjct: 241 PVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLN 300
Query: 301 VDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERA 360
VDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERA
Sbjct: 301 VDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERA 360
Query: 361 IGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKA 420
IGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKA
Sbjct: 361 IGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKA 420
Query: 421 FGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASL 480
FGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASL
Sbjct: 421 FGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASL 480
Query: 481 YNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVL 540
YNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVL
Sbjct: 481 YNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYHNVL 540
Query: 541 SNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC 585
SNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC
Sbjct: 541 SNWNRLRDRQYSVTDALEDVSTSPQSTEEVVQSFLISQNVEGPSC 585
>gi|34304360 nephrocystin 3 [Homo sapiens]
Length = 1330
Score = 69.3 bits (168), Expect = 9e-12
Identities = 63/251 (25%), Positives = 119/251 (47%), Gaps = 18/251 (7%)
Query: 295 GFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNAL 354
G +L ++ + Q++ Q +L+IR++ + VA + LA S YV KF NA
Sbjct: 950 GRFLKDLGLLSQAIVPLQRSLEIRETALDPDHPRVAQSLHQLA-SVYVQWK---KFGNAE 1005
Query: 355 FHAERAIGIITHILPEDHLLLASSKRVKALILE-----EIAIDCHNK--ETEQRLLQEAH 407
++A+ I + DH A A + + E A K + Q+ +++
Sbjct: 1006 QLYKQALEISENAYGADHPYTARELEALATLYQKQNKYEQAEHFRKKSFKIHQKAIKKKG 1065
Query: 408 DLH------LSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQ 461
+L+ +LQL + G+ A+ LG LY + A++ ++++++E+
Sbjct: 1066 NLYGFALLRRRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRER 1125
Query: 462 LLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLI 521
+LG + + A S+ +LA+L N + QY+ AE+LY R++ I ++ + L Y + L
Sbjct: 1126 VLGPDHPDCAQSLNNLAALCN-EKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLA 1184
Query: 522 KLYNSIGNYEK 532
LY +G +K
Sbjct: 1185 ILYKKMGKLDK 1195
Score = 62.4 bits (150), Expect = 1e-09
Identities = 59/257 (22%), Positives = 115/257 (44%), Gaps = 18/257 (7%)
Query: 284 HPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVH 343
HP+ + +L + + +Y+ AL+I ++ +G + + A E LA + Y
Sbjct: 981 HPRVAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYGADHPYTARELEALA-TLYQK 1039
Query: 344 QYSSGKFDNALFHAERAIGIITH-ILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRL 402
Q K++ A +++ I I + +L + R +AL LEE+ + + + L
Sbjct: 1040 Q---NKYEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQLEELTLGKDTPDNARTL 1096
Query: 403 ------------LQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEE 450
L+ A SL++ ++ G + A+ NL L +++ +AEE
Sbjct: 1097 NELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLNNLAALCNEKKQYDKAEE 1156
Query: 451 MHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGY 510
++ +A+ I+ + L + +A +V HLA LY M + + A LY ++ I +K FG +
Sbjct: 1157 LYERALDIRRRALAPDHPSLAYTVKHLAILYK-KMGKLDKAVPLYELAVEIRQKSFGPKH 1215
Query: 511 SGLEYDYRGLIKLYNSI 527
+ L LY+ +
Sbjct: 1216 PSVATALVNLAVLYSQM 1232
Score = 60.8 bits (146), Expect = 3e-09
Identities = 71/314 (22%), Positives = 137/314 (43%), Gaps = 34/314 (10%)
Query: 245 VVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNI 304
V L Q + V ++F AEQL K A+ ++ + +G+ HP Y+ L+ L N
Sbjct: 984 VAQSLHQLASVYVQWKKFGNAEQLYKQALEISENAYGADHP-YTARELEALATLYQKQNK 1042
Query: 305 CQ--------SVAIYQAALDIRQSVFG-------GKNIHVATAHEDLAYSSY------VH 343
+ S I+Q A+ + +++G + T +D ++ V
Sbjct: 1043 YEQAEHFRKKSFKIHQKAIKKKGNLYGFALLRRRALQLEELTLGKDTPDNARTLNELGVL 1102
Query: 344 QYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLL 403
Y + A +R++ + +L DH A S L +A C+ E++
Sbjct: 1103 YYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQS-------LNNLAALCN----EKKQY 1151
Query: 404 QEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLL 463
+A +L+ +L + ++A + A +L LY+ M K +A ++ A++I+++
Sbjct: 1152 DKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPLYELAVEIRQKSF 1211
Query: 464 GQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKL 523
G + VA ++ +LA LY+ M ++ A LY R++ I + G + + + L L
Sbjct: 1212 GPKHPSVATALVNLAVLYS-QMKKHVEALPLYERALKIYEDSLGRMHPRVGETLKNLAVL 1270
Query: 524 YNSIGNYEKVFEYH 537
G++EK E +
Sbjct: 1271 SYEGGDFEKAAELY 1284
Score = 60.5 bits (145), Expect = 4e-09
Identities = 59/234 (25%), Positives = 110/234 (47%), Gaps = 16/234 (6%)
Query: 268 LIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNI 327
L + A+ L G P + TL + G +N+ + + +L++R+ V G +
Sbjct: 1073 LRRRALQLEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHP 1132
Query: 328 HVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILE 387
A + +LA + ++D A ERA+ I L DH LA + + A++ +
Sbjct: 1133 DCAQSLNNLAALCNEKK----QYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYK 1188
Query: 388 EIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKE 447
++ L +A L+ ++++ +K+FG + A NL LY M+K E
Sbjct: 1189 KMG-----------KLDKAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVE 1237
Query: 448 AEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAI 501
A ++ +A++I E LG+ V ++ +LA L +Y+ +E A +LY R++ I
Sbjct: 1238 ALPLYERALKIYEDSLGRMHPRVGETLKNLAVL-SYEGGDFEKAAELYKRAMEI 1290
Score = 50.8 bits (120), Expect = 3e-06
Identities = 36/147 (24%), Positives = 70/147 (47%), Gaps = 2/147 (1%)
Query: 193 MDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEA--MKEITAGLPVKVVVDVLR 250
+++L+ + A EL L + +++ + A ++ + M+E G L
Sbjct: 1080 LEELTLGKDTPDNARTLNELGVLYYLQNNLETADQFLKRSLEMRERVLGPDHPDCAQSLN 1139
Query: 251 QASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAI 310
+ C K+++ KAE+L + A+ + R HP + T+ + + ++V +
Sbjct: 1140 NLAALCNEKKQYDKAEELYERALDIRRRALAPDHPSLAYTVKHLAILYKKMGKLDKAVPL 1199
Query: 311 YQAALDIRQSVFGGKNIHVATAHEDLA 337
Y+ A++IRQ FG K+ VATA +LA
Sbjct: 1200 YELAVEIRQKSFGPKHPSVATALVNLA 1226
Score = 46.2 bits (108), Expect = 8e-05
Identities = 33/119 (27%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
Query: 415 QLAKKAFGEFNVQT-AKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALS 473
Q K GE N+ A Y LGR + + +A ++++I+E L + VA S
Sbjct: 928 QYEKNCEGEDNMSCLADLYETLGRFLKDLGLLSQAIVPLQRSLEIRETALDPDHPRVAQS 987
Query: 474 VGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
+ LAS+Y ++ NAE+LY +++ I + +G + + L LY YE+
Sbjct: 988 LHQLASVY-VQWKKFGNAEQLYKQALEISENAYGADHPYTARELEALATLYQKQNKYEQ 1045
Score = 37.7 bits (86), Expect = 0.030
Identities = 27/100 (27%), Positives = 46/100 (46%), Gaps = 4/100 (4%)
Query: 264 KAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFG 323
KA L + AV + + FG KHP + L++ + +++ +Y+ AL I + G
Sbjct: 1195 KAVPLYELAVEIRQKSFGPKHPSVATALVNLAVLYSQMKKHVEALPLYERALKIYEDSLG 1254
Query: 324 GKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGI 363
+ V ++LA V Y G F+ A +RA+ I
Sbjct: 1255 RMHPRVGETLKNLA----VLSYEGGDFEKAAELYKRAMEI 1290
>gi|194306559 kinesin light chain 1 isoform 3 [Homo sapiens]
Length = 618
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/231 (24%), Positives = 109/231 (47%), Gaps = 18/231 (7%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 220 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 268
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
++A +L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 269 NKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 328
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG++ +VA + +LA L + +YE E Y R++ I + G + L
Sbjct: 329 KVLGKDHPDVAKQLNNLALLCQ-NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNL 387
Query: 521 IKLYNSIGNYEKVFE-YHNVLSNWNRLRDRQY-SVTDALEDVSTSPQSTEE 569
Y G +++ Y +L+ R +R++ SV D + + + EE
Sbjct: 388 ASCYLKQGKFKQAETLYKEILT---RAHEREFGSVDDENKPIWMHAEEREE 435
Score = 48.1 bits (113), Expect = 2e-05
Identities = 66/286 (23%), Positives = 112/286 (39%), Gaps = 19/286 (6%)
Query: 178 KYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAM--KE 235
+Y + K A ++K S H + A + L + ++ Y +A +A+ +E
Sbjct: 228 RYEVAVPLCKQALEDLEKTSGH-DHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRE 286
Query: 236 ITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYG 295
T G V L + + ++K+AE L K A+ + G HP + L +
Sbjct: 287 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLA 346
Query: 296 FYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALF 355
N + YQ AL+I Q+ G + +VA +LA S Y+ Q GKF A
Sbjct: 347 LLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLA-SCYLKQ---GKFKQA-- 400
Query: 356 HAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQ 415
L ++ L A + ++ E I H +E E+ ++
Sbjct: 401 ----------ETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYG 450
Query: 416 LAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQ 461
KA + NLG LY+ KF+ AE + A++ ++Q
Sbjct: 451 GWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQ 496
>gi|110735431 kinesin light chain 1 isoform 2 [Homo sapiens]
Length = 573
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/231 (24%), Positives = 109/231 (47%), Gaps = 18/231 (7%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 220 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 268
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
++A +L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 269 NKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 328
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG++ +VA + +LA L + +YE E Y R++ I + G + L
Sbjct: 329 KVLGKDHPDVAKQLNNLALLCQ-NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNL 387
Query: 521 IKLYNSIGNYEKVFE-YHNVLSNWNRLRDRQY-SVTDALEDVSTSPQSTEE 569
Y G +++ Y +L+ R +R++ SV D + + + EE
Sbjct: 388 ASCYLKQGKFKQAETLYKEILT---RAHEREFGSVDDENKPIWMHAEEREE 435
Score = 48.1 bits (113), Expect = 2e-05
Identities = 66/286 (23%), Positives = 112/286 (39%), Gaps = 19/286 (6%)
Query: 178 KYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAM--KE 235
+Y + K A ++K S H + A + L + ++ Y +A +A+ +E
Sbjct: 228 RYEVAVPLCKQALEDLEKTSGH-DHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRE 286
Query: 236 ITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYG 295
T G V L + + ++K+AE L K A+ + G HP + L +
Sbjct: 287 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLA 346
Query: 296 FYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALF 355
N + YQ AL+I Q+ G + +VA +LA S Y+ Q GKF A
Sbjct: 347 LLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLA-SCYLKQ---GKFKQA-- 400
Query: 356 HAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQ 415
L ++ L A + ++ E I H +E E+ ++
Sbjct: 401 ----------ETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYG 450
Query: 416 LAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQ 461
KA + NLG LY+ KF+ AE + A++ ++Q
Sbjct: 451 GWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQ 496
>gi|33620730 kinesin light chain 1 isoform 1 [Homo sapiens]
Length = 560
Score = 60.8 bits (146), Expect = 3e-09
Identities = 57/231 (24%), Positives = 109/231 (47%), Gaps = 18/231 (7%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 220 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 268
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
++A +L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 269 NKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 328
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG++ +VA + +LA L + +YE E Y R++ I + G + L
Sbjct: 329 KVLGKDHPDVAKQLNNLALLCQ-NQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNL 387
Query: 521 IKLYNSIGNYEKVFE-YHNVLSNWNRLRDRQY-SVTDALEDVSTSPQSTEE 569
Y G +++ Y +L+ R +R++ SV D + + + EE
Sbjct: 388 ASCYLKQGKFKQAETLYKEILT---RAHEREFGSVDDENKPIWMHAEEREE 435
Score = 48.1 bits (113), Expect = 2e-05
Identities = 66/286 (23%), Positives = 112/286 (39%), Gaps = 19/286 (6%)
Query: 178 KYHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAM--KE 235
+Y + K A ++K S H + A + L + ++ Y +A +A+ +E
Sbjct: 228 RYEVAVPLCKQALEDLEKTSGH-DHPDVATMLNILALVYRDQNKYKDAANLLNDALAIRE 286
Query: 236 ITAGLPVKVVVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYG 295
T G V L + + ++K+AE L K A+ + G HP + L +
Sbjct: 287 KTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQLNNLA 346
Query: 296 FYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALF 355
N + YQ AL+I Q+ G + +VA +LA S Y+ Q GKF A
Sbjct: 347 LLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLA-SCYLKQ---GKFKQA-- 400
Query: 356 HAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQ 415
L ++ L A + ++ E I H +E E+ ++
Sbjct: 401 ----------ETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQKDGTSFGEYG 450
Query: 416 LAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQ 461
KA + NLG LY+ KF+ AE + A++ ++Q
Sbjct: 451 GWYKACKVDSPTVTTTLKNLGALYRRQGKFEAAETLEEAAMRSRKQ 496
>gi|91825557 kinesin light chain 3 [Homo sapiens]
Length = 504
Score = 57.0 bits (136), Expect = 5e-08
Identities = 37/139 (26%), Positives = 71/139 (51%), Gaps = 1/139 (0%)
Query: 399 EQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQI 458
+Q +EA DL +LQ+ ++ G + A NL LY +++EAE + +A++I
Sbjct: 261 DQNKYKEATDLLHDALQIREQTLGPEHPAVAATLNNLAVLYGKRGRYREAEPLCQRALEI 320
Query: 459 KEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYR 518
+E++LG + +VA + +LA L + ++E+ E+ Y R+++I + L G +
Sbjct: 321 REKVLGADHPDVAKQLNNLALLCQ-NQGKFEDVERHYARALSIYEALGGPHDPNVAKTKN 379
Query: 519 GLIKLYNSIGNYEKVFEYH 537
L Y Y++ E +
Sbjct: 380 NLASAYLKQNKYQQAEELY 398
Score = 55.8 bits (133), Expect = 1e-07
Identities = 36/125 (28%), Positives = 63/125 (50%), Gaps = 1/125 (0%)
Query: 413 SLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVAL 472
+L+ +++ G + A L +Y+ K+KEA ++ A+QI+EQ LG E VA
Sbjct: 233 ALEDLERSSGHCHPDVATMLNILALVYRDQNKYKEATDLLHDALQIREQTLGPEHPAVAA 292
Query: 473 SVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
++ +LA LY +Y AE L R++ I +K+ G + + L L + G +E
Sbjct: 293 TLNNLAVLYG-KRGRYREAEPLCQRALEIREKVLGADHPDVAKQLNNLALLCQNQGKFED 351
Query: 533 VFEYH 537
V ++
Sbjct: 352 VERHY 356
>gi|41871960 kinesin-like 8 isoform b [Homo sapiens]
Length = 637
Score = 55.5 bits (132), Expect = 1e-07
Identities = 48/190 (25%), Positives = 86/190 (45%), Gaps = 13/190 (6%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY++ G+++ A+ ++A+ + H +A+ + AL+ + Q
Sbjct: 236 VIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRD-----------Q 284
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
+EA L +L + + G + A NL LY K+KEAE + +A++I+E
Sbjct: 285 NKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRE 344
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG +VA + +LA L + +YE E+ Y R++AI + G + L
Sbjct: 345 KVLGTNHPDVAKQLNNLALLCQ-NQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNL 403
Query: 521 IKLYNSIGNY 530
Y G Y
Sbjct: 404 ASCYLKQGKY 413
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/194 (24%), Positives = 75/194 (38%), Gaps = 21/194 (10%)
Query: 262 FKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSV 321
++ A L K A+ G HP + L + + ++ + AL IR+S
Sbjct: 245 YEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREST 304
Query: 322 FGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRV 381
G + VA +LA V GK+ A +RA+ I +L +H +A
Sbjct: 305 LGPDHPAVAATLNNLA----VLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQ--- 357
Query: 382 KALILEEIAIDCHNK---ETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRL 438
L +A+ C N+ E +R Q A L + + G N A+ NL
Sbjct: 358 ----LNNLALLCQNQGKYEAVERYYQRA-------LAIYEGQLGPDNPNVARTKNNLASC 406
Query: 439 YQSMRKFKEAEEMH 452
Y K+ EAE ++
Sbjct: 407 YLKQGKYAEAETLY 420
Score = 33.9 bits (76), Expect = 0.43
Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Query: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
NL Y + +++ A + +A++ E+ G+ +VA + LA +Y D N+Y+ A
Sbjct: 234 NLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYR-DQNKYKEAAH 292
Query: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
L +++I + G + + L LY G Y++
Sbjct: 293 LLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 331
>gi|41871955 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 55.5 bits (132), Expect = 1e-07
Identities = 48/190 (25%), Positives = 86/190 (45%), Gaps = 13/190 (6%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY++ G+++ A+ ++A+ + H +A+ + AL+ + Q
Sbjct: 218 VIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRD-----------Q 266
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
+EA L +L + + G + A NL LY K+KEAE + +A++I+E
Sbjct: 267 NKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRE 326
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG +VA + +LA L + +YE E+ Y R++AI + G + L
Sbjct: 327 KVLGTNHPDVAKQLNNLALLCQ-NQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNL 385
Query: 521 IKLYNSIGNY 530
Y G Y
Sbjct: 386 ASCYLKQGKY 395
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/194 (24%), Positives = 75/194 (38%), Gaps = 21/194 (10%)
Query: 262 FKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSV 321
++ A L K A+ G HP + L + + ++ + AL IR+S
Sbjct: 227 YEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREST 286
Query: 322 FGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRV 381
G + VA +LA V GK+ A +RA+ I +L +H +A
Sbjct: 287 LGPDHPAVAATLNNLA----VLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQ--- 339
Query: 382 KALILEEIAIDCHNK---ETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRL 438
L +A+ C N+ E +R Q A L + + G N A+ NL
Sbjct: 340 ----LNNLALLCQNQGKYEAVERYYQRA-------LAIYEGQLGPDNPNVARTKNNLASC 388
Query: 439 YQSMRKFKEAEEMH 452
Y K+ EAE ++
Sbjct: 389 YLKQGKYAEAETLY 402
Score = 33.9 bits (76), Expect = 0.43
Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Query: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
NL Y + +++ A + +A++ E+ G+ +VA + LA +Y D N+Y+ A
Sbjct: 216 NLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYR-DQNKYKEAAH 274
Query: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
L +++I + G + + L LY G Y++
Sbjct: 275 LLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 313
>gi|41871946 kinesin-like 8 isoform a [Homo sapiens]
Length = 619
Score = 55.5 bits (132), Expect = 1e-07
Identities = 48/190 (25%), Positives = 86/190 (45%), Gaps = 13/190 (6%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY++ G+++ A+ ++A+ + H +A+ + AL+ + Q
Sbjct: 218 VIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRD-----------Q 266
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
+EA L +L + + G + A NL LY K+KEAE + +A++I+E
Sbjct: 267 NKYKEAAHLLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKEAEPLCQRALEIRE 326
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG +VA + +LA L + +YE E+ Y R++AI + G + L
Sbjct: 327 KVLGTNHPDVAKQLNNLALLCQ-NQGKYEAVERYYQRALAIYEGQLGPDNPNVARTKNNL 385
Query: 521 IKLYNSIGNY 530
Y G Y
Sbjct: 386 ASCYLKQGKY 395
Score = 38.1 bits (87), Expect = 0.023
Identities = 47/194 (24%), Positives = 75/194 (38%), Gaps = 21/194 (10%)
Query: 262 FKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSV 321
++ A L K A+ G HP + L + + ++ + AL IR+S
Sbjct: 227 YEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIREST 286
Query: 322 FGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRV 381
G + VA +LA V GK+ A +RA+ I +L +H +A
Sbjct: 287 LGPDHPAVAATLNNLA----VLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQ--- 339
Query: 382 KALILEEIAIDCHNK---ETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRL 438
L +A+ C N+ E +R Q A L + + G N A+ NL
Sbjct: 340 ----LNNLALLCQNQGKYEAVERYYQRA-------LAIYEGQLGPDNPNVARTKNNLASC 388
Query: 439 YQSMRKFKEAEEMH 452
Y K+ EAE ++
Sbjct: 389 YLKQGKYAEAETLY 402
Score = 33.9 bits (76), Expect = 0.43
Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 1/99 (1%)
Query: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
NL Y + +++ A + +A++ E+ G+ +VA + LA +Y D N+Y+ A
Sbjct: 216 NLVIQYAAQGRYEVAVPLCKQALEDLERTSGRGHPDVATMLNILALVYR-DQNKYKEAAH 274
Query: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
L +++I + G + + L LY G Y++
Sbjct: 275 LLNDALSIRESTLGPDHPAVAATLNNLAVLYGKRGKYKE 313
>gi|198041734 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 13/191 (6%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 205 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 253
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
+EA L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 254 NKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 313
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG+ +VA + +LA L + + E E Y R++ I G + L
Sbjct: 314 KVLGKFHPDVAKQLSNLALLCQ-NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 372
Query: 521 IKLYNSIGNYE 531
Y G Y+
Sbjct: 373 ASCYLKQGKYQ 383
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
NL Y S +++ A + +A++ E+ G + +VA + LA +Y D N+Y+ A
Sbjct: 203 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR-DQNKYKEAAH 261
Query: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
L ++AI +K G+ + + L LY G Y++
Sbjct: 262 LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
>gi|198041731 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 13/191 (6%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 205 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 253
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
+EA L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 254 NKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 313
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG+ +VA + +LA L + + E E Y R++ I G + L
Sbjct: 314 KVLGKFHPDVAKQLSNLALLCQ-NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 372
Query: 521 IKLYNSIGNYE 531
Y G Y+
Sbjct: 373 ASCYLKQGKYQ 383
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
NL Y S +++ A + +A++ E+ G + +VA + LA +Y D N+Y+ A
Sbjct: 203 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR-DQNKYKEAAH 261
Query: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
L ++AI +K G+ + + L LY G Y++
Sbjct: 262 LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
>gi|198041728 kinesin light chain 2 isoform 2 [Homo sapiens]
Length = 545
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 13/191 (6%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 128 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 176
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
+EA L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 177 NKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 236
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG+ +VA + +LA L + + E E Y R++ I G + L
Sbjct: 237 KVLGKFHPDVAKQLSNLALLCQ-NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 295
Query: 521 IKLYNSIGNYE 531
Y G Y+
Sbjct: 296 ASCYLKQGKYQ 306
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
NL Y S +++ A + +A++ E+ G + +VA + LA +Y D N+Y+ A
Sbjct: 126 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR-DQNKYKEAAH 184
Query: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
L ++AI +K G+ + + L LY G Y++
Sbjct: 185 LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 223
>gi|12383062 kinesin light chain 2 isoform 1 [Homo sapiens]
Length = 622
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/191 (25%), Positives = 87/191 (45%), Gaps = 13/191 (6%)
Query: 342 VHQYSS-GKFDNALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKETEQ 400
V QY+S G+++ A+ ++A+ + DH +A+ + AL+ + Q
Sbjct: 205 VIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRD-----------Q 253
Query: 401 RLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKE 460
+EA L +L + +K G+ + A NL LY K+KEAE + +A++I+E
Sbjct: 254 NKYKEAAHLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIRE 313
Query: 461 QLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGL 520
++LG+ +VA + +LA L + + E E Y R++ I G + L
Sbjct: 314 KVLGKFHPDVAKQLSNLALLCQ-NQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNL 372
Query: 521 IKLYNSIGNYE 531
Y G Y+
Sbjct: 373 ASCYLKQGKYQ 383
Score = 40.0 bits (92), Expect = 0.006
Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
Query: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
NL Y S +++ A + +A++ E+ G + +VA + LA +Y D N+Y+ A
Sbjct: 203 NLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR-DQNKYKEAAH 261
Query: 494 LYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
L ++AI +K G+ + + L LY G Y++
Sbjct: 262 LLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKE 300
>gi|87162455 hypothetical protein LOC23277 [Homo sapiens]
Length = 1309
Score = 44.3 bits (103), Expect = 3e-04
Identities = 37/132 (28%), Positives = 60/132 (45%), Gaps = 8/132 (6%)
Query: 397 ETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAI 456
+ +Q L+E +L +L L +G +V+T L RL+ M + EA KA+
Sbjct: 988 KVQQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSNQQKAV 1047
Query: 457 QIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYD 516
+ E+++G E HLA LY + +Q A L R+ + +FGE D
Sbjct: 1048 LMSERVMGTEHPNTIQEYMHLA-LYCFASSQLSTALSLLYRARYLMLLVFGE-------D 1099
Query: 517 YRGLIKLYNSIG 528
+ + L N+IG
Sbjct: 1100 HPEMALLDNNIG 1111
Score = 38.9 bits (89), Expect = 0.013
Identities = 52/195 (26%), Positives = 79/195 (40%), Gaps = 14/195 (7%)
Query: 207 ALYGELCALL--FAKSHY-----DEAYKWCIEA--MKEITAGLPVKVVVDVLRQASKACV 257
A++ E CA L A+ HY EA +A M E G + + C
Sbjct: 1014 AMHVETCACLRLLARLHYIMGDYAEALSNQQKAVLMSERVMGTEHPNTIQEYMHLALYCF 1073
Query: 258 VKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDI 317
+ A L+ A YL FG HP+ + + G L V S+ + AL +
Sbjct: 1074 ASSQLSTALSLLYRARYLMLLVFGEDHPEMALLDNNIGLVLHGVMEYDLSLRFLENALAV 1133
Query: 318 RQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDH-LLLA 376
G K + VA +H +A V++ S +F +AL H + I L EDH
Sbjct: 1134 STKYHGPKALKVALSHHLVA---RVYE-SKAEFRSALQHEKEGYTIYKTQLGEDHEKTKE 1189
Query: 377 SSKRVKALILEEIAI 391
SS+ +K L + +A+
Sbjct: 1190 SSEYLKCLTQQAVAL 1204
Score = 34.3 bits (77), Expect = 0.33
Identities = 46/219 (21%), Positives = 96/219 (43%), Gaps = 16/219 (7%)
Query: 251 QASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAI 310
Q+ +A V + K+ +LI A+ L + +G+ H + L + + ++++
Sbjct: 983 QSGQAKVQQGFLKEGCELINEALNLFNNVYGAMHVETCACLRLLARLHYIMGDYAEALSN 1042
Query: 311 YQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPE 370
Q A+ + + V G ++ + + LA ++ ++S + AL RA ++ + E
Sbjct: 1043 QQKAVLMSERVMGTEHPNTIQEYMHLA----LYCFASSQLSTALSLLYRARYLMLLVFGE 1098
Query: 371 DHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAK 430
DH +A L+L + + R L+ A L ++ K G ++ A
Sbjct: 1099 DHPEMALLDNNIGLVLHGVM----EYDLSLRFLENA-------LAVSTKYHGPKALKVAL 1147
Query: 431 HYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYE 469
+ + R+Y+S +F+ A + + I + LG ED+E
Sbjct: 1148 SHHLVARVYESKAEFRSALQHEKEGYTIYKTQLG-EDHE 1185
>gi|224809432 transmembrane and tetratricopeptide repeat containing
3 [Homo sapiens]
Length = 914
Score = 41.2 bits (95), Expect = 0.003
Identities = 21/74 (28%), Positives = 44/74 (59%), Gaps = 6/74 (8%)
Query: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGH------LASLYNYDMNQ 487
N+GR Y+++ + KEAEE ++ A + Q++ + Y ++ H LA+L + ++
Sbjct: 485 NVGRTYKNLNRTKEAEESYMMAKSLMPQIIPGKKYAARIAPNHLNVYINLANLIRANESR 544
Query: 488 YENAEKLYLRSIAI 501
E A++LY ++I++
Sbjct: 545 LEEADQLYRQAISM 558
Score = 29.6 bits (65), Expect = 8.0
Identities = 51/220 (23%), Positives = 89/220 (40%), Gaps = 52/220 (23%)
Query: 263 KKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVF 322
++A+QL + A+ S P + + G LL ++ ++ Y AL++ ++
Sbjct: 546 EEADQLYRQAI--------SMRPDFKQAYISRGELLLKMNKPLKAKEAYLKALELDRN-- 595
Query: 323 GGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIITHILPEDHLLLASSKRVK 382
+ DL Y+ + + + AL + RA+ + P+ L L +S
Sbjct: 596 ----------NADLWYNLAIVHIELKEPNEALKNFNRAL----ELNPKHKLALFNS---- 637
Query: 383 ALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSM 442
A++++E E +RLL ++ L A Y NLG L
Sbjct: 638 AIVMQESGEVKLRPEARKRLLSYINEEPLD----------------ANGYFNLGMLAMDD 681
Query: 443 RKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYN 482
+K EAE KAI++ Q D+ AL +LA LY+
Sbjct: 682 KKDNEAEIWMKKAIKL------QADFRSALF--NLALLYS 713
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 38.5 bits (88), Expect = 0.017
Identities = 82/395 (20%), Positives = 154/395 (38%), Gaps = 63/395 (15%)
Query: 179 YHLGEETFKLAQTYMDKLSKHGQQANKAALYGELCALL----FAKSHYDEAYKWCIEAMK 234
+H + A Y ++ + G++C L + +Y EA K+ + +
Sbjct: 603 FHCSRGEYVQAAPYYEQYLRLAPDLQDMEGEGKVCHNLGYAHYCLGNYQEAVKYYEQDLA 662
Query: 235 EITAGLPVKVVVDVLRQASKACVVKREFK------KAEQLIKHAVYLARDHFGSKHPKYS 288
K + D L QA C + FK KAE+ K+ + LA+ + K+
Sbjct: 663 L------AKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQS-LNNSQAKFR 715
Query: 289 DTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSG 348
L + G + +I ++ Y+ L + V + A A AY
Sbjct: 716 -ALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQ------ 768
Query: 349 KFDNALFHAERAIGIITHI--LPED-----HLL---LASSKRVKALILEEIAIDCHNKET 398
K+D AL + + + + + LP + HL +A K A E +D K
Sbjct: 769 KYDKALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLK 828
Query: 399 EQRLLQEAHD---LHLSSLQLAKKAFGEFNVQTA---------------KHYGNLGRLYQ 440
+ L + + + ++ + ++A G F Q A + YGNLG Y+
Sbjct: 829 DPSLEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYE 888
Query: 441 SMRKFKEAEEMHIKAIQIKEQLLGQEDYEVA---LSVGHLASLYNYDMNQYENAEKLYLR 497
++ ++EA + + + + + + L +D A L GH A M + A + +
Sbjct: 889 ALGDYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRA------MGSLQQALVCFEK 942
Query: 498 SIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEK 532
+ + +L GE ++ + Y L L++ +GNYE+
Sbjct: 943 RLVVAHEL-GEAFNKAQ-AYGELGSLHSQLGNYEQ 975
Score = 38.1 bits (87), Expect = 0.023
Identities = 32/135 (23%), Positives = 60/135 (44%), Gaps = 7/135 (5%)
Query: 404 QEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLL 463
+EA H L LA K +A +LG +Y ++ + A H + + + +Q
Sbjct: 291 REALTNHRHQLVLAMKLKDREAASSA--LSSLGHVYTAIGDYPNALASHKQCVLLAKQ-- 346
Query: 464 GQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKL 523
+++ A +G++ ++Y M +ENA + + + + I K L + Y G
Sbjct: 347 SKDELSEARELGNMGAVY-IAMGDFENAVQCHEQHLKIAKDLGNKREEARAYSNLG--SA 403
Query: 524 YNSIGNYEKVFEYHN 538
Y+ N++K YHN
Sbjct: 404 YHYRRNFDKAMSYHN 418
Score = 36.2 bits (82), Expect = 0.086
Identities = 30/135 (22%), Positives = 57/135 (42%), Gaps = 9/135 (6%)
Query: 404 QEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLL 463
+ A H L++AK + + A+ Y NLG Y R F +A H +++ ++L+
Sbjct: 371 ENAVQCHEQHLKIAKDLGNKR--EEARAYSNLGSAYHYRRNFDKAMSYHNYVLELAQELM 428
Query: 464 GQE-DYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIK 522
+ + +GH A M E A++ + + + I + L G G+I
Sbjct: 429 EKAIEMRAYAGLGHAARC----MQDLERAKQYHEQQLGIAEDLKDRAAEGRASSNLGII- 483
Query: 523 LYNSIGNYEKVFEYH 537
+ G+Y+ + H
Sbjct: 484 -HQMKGDYDTALKLH 497
Score = 35.8 bits (81), Expect = 0.11
Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 7/112 (6%)
Query: 429 AKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQY 488
AK Y LG +++M ++A K + + +L E + A + G L SL++ + Y
Sbjct: 917 AKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHEL--GEAFNKAQAYGELGSLHS-QLGNY 973
Query: 489 ENAEKLYLRSIAIGKKLFGEGYSGLEYDYR-GLIKLYNSIGNYEKVFEYHNV 539
E A R + I + + LE D GL +Y +G Y+ +YH +
Sbjct: 974 EQAISCLERQLNIARDMKDRA---LESDAACGLGGVYQQMGEYDTALQYHQL 1022
Score = 31.2 bits (69), Expect = 2.8
Identities = 26/107 (24%), Positives = 49/107 (45%), Gaps = 7/107 (6%)
Query: 432 YGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVAL-SVGHLASLYNYDMNQYEN 490
+GNLG + S ++EA H + + +L +E AL S+GH+ + + Y N
Sbjct: 277 HGNLGSAFFSKGNYREALTNHRHQLVLAMKLKDREAASSALSSLGHVYTA----IGDYPN 332
Query: 491 AEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYNSIGNYEKVFEYH 537
A + + + + K+ E E G + Y ++G++E + H
Sbjct: 333 ALASHKQCVLLAKQSKDELSEARELGNMGAV--YIAMGDFENAVQCH 377
Score = 31.2 bits (69), Expect = 2.8
Identities = 31/132 (23%), Positives = 63/132 (47%), Gaps = 13/132 (9%)
Query: 409 LHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDY 468
LH + L +A++ ++ Q + YGN+G Y ++ + +A + H + +QI ++ +
Sbjct: 496 LHKTHLCIAQE-LSDYAAQ-GRAYGNMGNAYNALGMYDQAVKYHRQELQISMEV--NDRA 551
Query: 469 EVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIKLYN--- 525
A + G+LA Y + ++ A + Y + I ++L ++ + R L L N
Sbjct: 552 SQASTHGNLAVAYQ-ALGAHDRALQHYQNHLNIAREL-----RDIQSEARALSNLGNFHC 605
Query: 526 SIGNYEKVFEYH 537
S G Y + Y+
Sbjct: 606 SRGEYVQAAPYY 617
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 35.0 bits (79), Expect = 0.19
Identities = 39/198 (19%), Positives = 72/198 (36%), Gaps = 22/198 (11%)
Query: 127 GGFLSDAGWYSDAEKVFLSCLQLC--TLHDEMLHWFRAVECCVRLLHVRNGNCKYHLGEE 184
G L + G +A + FL C ++ L D H C L + YH
Sbjct: 568 GIILMNQGRTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKL------YHEQGH 621
Query: 185 TFKLAQTYMDKLSKHGQQANKAALYGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKV 244
+ Y + + K +Q +LY + S EA W +E+++ T +P +
Sbjct: 622 YEEALSVYKEAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHL 681
Query: 245 VVDVLRQASKACVVKREFKKAEQLIKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNI 304
K + +AE+L A+ L P + + YG +LL +
Sbjct: 682 TY------GKLLALTGRKSEAEKLFLKAIEL--------DPTKGNCYMHYGQFLLEEARL 727
Query: 305 CQSVAIYQAALDIRQSVF 322
++ + + A ++ + F
Sbjct: 728 IEAAEMAKKAAELDSTEF 745
Score = 32.7 bits (73), Expect = 0.95
Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 17/82 (20%)
Query: 426 VQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDM 485
V AK +GNLG + +S K EAE + A+ + + LYN +
Sbjct: 490 VNPAKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADM--------------LYNLGL 535
Query: 486 NQYEN---AEKLYLRSIAIGKK 504
EN AE L+ +AIG +
Sbjct: 536 LLQENSRFAEALHYYKLAIGSR 557
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 34.7 bits (78), Expect = 0.25
Identities = 22/68 (32%), Positives = 38/68 (55%), Gaps = 10/68 (14%)
Query: 434 NLGRLYQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEK 493
NLGRLY+S+ + AEE + +A+Q+ + A + L +LY Y+ +YE A +
Sbjct: 547 NLGRLYRSLGENSMAEEWYKRALQVAHK---------AEILSPLGALY-YNTGRYEEALQ 596
Query: 494 LYLRSIAI 501
+Y + A+
Sbjct: 597 IYQEAAAL 604
>gi|224548927 G-protein signaling modulator 1 (AGS3-like, C.
elegans) isoform a [Homo sapiens]
Length = 675
Score = 32.7 bits (73), Expect = 0.95
Identities = 30/135 (22%), Positives = 63/135 (46%), Gaps = 7/135 (5%)
Query: 403 LQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQL 462
L +A + + +L L K+ G+ Q + YGNLG + + F EA H + + I ++
Sbjct: 185 LCKASEFYERNLSLVKE-LGDRAAQ-GRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEF 242
Query: 463 LGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIK 522
+ A S +L + + + + +++ A + Y +++ + ++L + G
Sbjct: 243 GDKAAERRAYS--NLGNAHVF-LGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLG--N 297
Query: 523 LYNSIGNYEKVFEYH 537
Y + +YE+ EYH
Sbjct: 298 TYTLLQDYERAAEYH 312
>gi|224548925 G-protein signaling modulator 1 (AGS3-like, C.
elegans) isoform b [Homo sapiens]
Length = 457
Score = 32.7 bits (73), Expect = 0.95
Identities = 30/135 (22%), Positives = 63/135 (46%), Gaps = 7/135 (5%)
Query: 403 LQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQIKEQL 462
L +A + + +L L K+ G+ Q + YGNLG + + F EA H + + I ++
Sbjct: 185 LCKASEFYERNLSLVKE-LGDRAAQ-GRAYGNLGNTHYLLGNFTEATTFHKERLAIAKEF 242
Query: 463 LGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAIGKKLFGEGYSGLEYDYRGLIK 522
+ A S +L + + + + +++ A + Y +++ + ++L + G
Sbjct: 243 GDKAAERRAYS--NLGNAHVF-LGRFDVAAEYYKKTLQLSRQLRDQAVEAQACYSLG--N 297
Query: 523 LYNSIGNYEKVFEYH 537
Y + +YE+ EYH
Sbjct: 298 TYTLLQDYERAAEYH 312
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 32.0 bits (71), Expect = 1.6
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 9/77 (11%)
Query: 478 ASLYNYDMNQYENAEKLYLRSIAIGKK--------LFGEGYSGLEYDYRGLIKLYNSIGN 529
+SLYN D N EK A +K LFGE Y + D ++ N +GN
Sbjct: 5 SSLYNDDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYKTAKGDELSS-RIQNMLGN 63
Query: 530 YEKVFEYHNVLSNWNRL 546
YE+V E+ + S+ +RL
Sbjct: 64 YEEVKEFLSTKSHTHRL 80
>gi|22547159 tetratricopeptide repeat domain 19 [Homo sapiens]
Length = 501
Score = 32.0 bits (71), Expect = 1.6
Identities = 33/132 (25%), Positives = 58/132 (43%), Gaps = 20/132 (15%)
Query: 297 YLLNVDNICQSVAIYQAALDIRQSVFGGKNIHVATAHEDLAYSSYVHQYSSGKFDNALFH 356
YLL Q+ +Y+ AL I + + G ++ DLA + + G+FD A +
Sbjct: 367 YLLFSKQPSQAQRMYEKALQISEEIQGERHPQTIVLMSDLATT----LDAQGRFDEAYIY 422
Query: 357 AERAIGIITHI-LPEDHLLLASSKRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQ 415
+RA + I PE H++L++ A+ H + Q A +++ +L+
Sbjct: 423 MQRASDLARQINHPELHMVLSNL----------AAVLMHRERYTQ-----AKEIYQEALK 467
Query: 416 LAKKAFGEFNVQ 427
AK E +VQ
Sbjct: 468 QAKLKKDEISVQ 479
>gi|7657265 fem-1 homolog b [Homo sapiens]
Length = 627
Score = 31.6 bits (70), Expect = 2.1
Identities = 29/134 (21%), Positives = 68/134 (50%), Gaps = 11/134 (8%)
Query: 379 KRVKALILEEIAIDCHNKETEQRLLQEAHDLHLSSLQLAKKAFG--EFNVQTAKH-YGNL 435
+R + LE + N +++ H L+L+ L+ + E V H YGN
Sbjct: 246 RRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNR 305
Query: 436 GRL-----YQSMRKFKEAEEMHIKAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYEN 490
+S+R+ ++A +H++ + ++E++LG ++ +V+ + + ++Y +M ++E
Sbjct: 306 TECRNPQELESIRQDRDA--LHMEGLIVRERILGADNIDVSHPIIYRGAVYADNM-EFEQ 362
Query: 491 AEKLYLRSIAIGKK 504
KL+L ++ + +K
Sbjct: 363 CIKLWLHALHLRQK 376
>gi|31982927 acetoacetyl-CoA synthetase [Homo sapiens]
Length = 672
Score = 31.6 bits (70), Expect = 2.1
Identities = 32/116 (27%), Positives = 47/116 (40%), Gaps = 21/116 (18%)
Query: 182 GEETFKLAQTYMDKLSKHGQQANK-AALYGELCALLFAKSHYDEAYKWCIEAMKEITA-- 238
G E Q + SK Q ++ A G C L A YD+ Y W +E+ + A
Sbjct: 8 GREEILECQVMWEPDSKKNTQMDRFRAAVGAACGL--ALESYDDLYHWSVESYSDFWAEF 65
Query: 239 ----GLPVKVVVDVLRQASKACVVKREFKK------AEQLIKH------AVYLARD 278
G+ V D + SK E+ K AE L++H A+Y+AR+
Sbjct: 66 WKFSGIVFSRVYDEVVDTSKGIADVPEWFKGSRLNYAENLLRHKENDRVALYIARE 121
>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
sapiens]
Length = 788
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 2/108 (1%)
Query: 395 NKETEQRLLQEAHD-LHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHI 453
N+E E L+ A D L L+ + ++ E + A+ + LG + + +A E
Sbjct: 507 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQ 566
Query: 454 KAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAI 501
+ ++EQ L D +A + L Y Y+ +QY+ A + +SI +
Sbjct: 567 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYN-SQYDEAVAQFSKSIEV 613
>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
sapiens]
Length = 790
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 2/108 (1%)
Query: 395 NKETEQRLLQEAHD-LHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHI 453
N+E E L+ A D L L+ + ++ E + A+ + LG + + +A E
Sbjct: 509 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQ 568
Query: 454 KAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAI 501
+ ++EQ L D +A + L Y Y+ +QY+ A + +SI +
Sbjct: 569 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYN-SQYDEAVAQFSKSIEV 615
>gi|27262630 nuclear autoantigenic sperm protein isoform 3 [Homo
sapiens]
Length = 449
Score = 31.2 bits (69), Expect = 2.8
Identities = 27/108 (25%), Positives = 50/108 (46%), Gaps = 2/108 (1%)
Query: 395 NKETEQRLLQEAHD-LHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHI 453
N+E E L+ A D L L+ + ++ E + A+ + LG + + +A E
Sbjct: 168 NEEEEIGNLELAWDMLDLAKIIFKRQETKEAQLYAAQAHLKLGEVSVESENYVQAVEEFQ 227
Query: 454 KAIQIKEQLLGQEDYEVALSVGHLASLYNYDMNQYENAEKLYLRSIAI 501
+ ++EQ L D +A + L Y Y+ +QY+ A + +SI +
Sbjct: 228 SCLNLQEQYLEAHDRLLAETHYQLGLAYGYN-SQYDEAVAQFSKSIEV 274
>gi|21686971 UDP-N-acetyl-alpha-D-galactosamine:polypeptide
N-acetylgalactosaminyltransferase-like 5 [Homo sapiens]
Length = 443
Score = 31.2 bits (69), Expect = 2.8
Identities = 40/177 (22%), Positives = 68/177 (38%), Gaps = 12/177 (6%)
Query: 209 YGELCALLFAKSHYDEAYKWCIEAMKEITAGLPVKVVVDVLRQASKACVVKREFKKAEQL 268
+G ALLF H++ W ++ + ++A P K V + S+ K
Sbjct: 16 FGIWTALLFIYLHHNHVSSWQKKSQEPLSAWSPGKKVHQQIIYGSEQIPKPHVIVKRTDE 75
Query: 269 IKHAVYLARDHFGSKHPKYSDTLLDYGFYLLNVDNICQSVAIYQAALDIRQSVFGGKNIH 328
K L D F +P+ LL YGF ++ I +S+ I + D R + K+
Sbjct: 76 DKAKSMLGTD-FNHTNPELHKELLKYGFNVI----ISRSLGIEREVPDTRSKMRLQKHYP 130
Query: 329 VATAHEDLAYSSYVHQYSSGKFDNALFHAERAIGIIT-HILPEDHLLLASSKRVKAL 384
+ Y + NALF ++ +T H E+ +L+ +V L
Sbjct: 131 ARLPTASIVICFYNEEC------NALFQTMSSVTNLTPHYFLEEIILVDDMSKVDDL 181
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 30.8 bits (68), Expect = 3.6
Identities = 41/195 (21%), Positives = 82/195 (42%), Gaps = 30/195 (15%)
Query: 286 KYSDTLLDYGFYLLNVDNICQSVAIYQAALD-----IRQSVFGGKNIHVATAHEDLAYSS 340
++SD LD ++ + + ++A L+ I++ + GKN+ AT +A
Sbjct: 7 EFSDCYLDSPWFR-------ERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRK 59
Query: 341 YVHQYSSGKFD---NALFHAERAIGIITHILPEDHLLLASSKRVKALILEEIAIDCHNKE 397
+ H KF+ +A+ ER I L + + AL + E I
Sbjct: 60 FAHSLRDFKFEFIGDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLI------ 113
Query: 398 TEQRLLQEAHDLHLSSLQLAKKAFGEFNVQTAKHYGNLGRLYQSMRKFKEAEEMHIKAIQ 457
+ L++ L +++ KK +F+ +T K+Y + + K K++ H++
Sbjct: 114 ---KPLEKFRKEQLGAVKEEKK---KFDKETEKNYSLIDKHLNLSAKKKDS---HLQEAD 164
Query: 458 IKEQLLGQEDYEVAL 472
I+ + Q YE++L
Sbjct: 165 IQVEQNRQHFYELSL 179
>gi|221625538 MORC family CW-type zinc finger 1 [Homo sapiens]
Length = 984
Score = 30.4 bits (67), Expect = 4.7
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 8/79 (10%)
Query: 341 YVHQYSSGKFDNALFHAERAIGIITHILPE--------DHLLLASSKRVKALILEEIAID 392
YV G F + + AE A+ I IL E D L+S+K V LE++
Sbjct: 276 YVTSSFKGAFKDEVKKAEEAVKIAESILKEAQIKVNQCDRTSLSSAKDVLQRALEDVEAK 335
Query: 393 CHNKETEQRLLQEAHDLHL 411
N + +QR L+ A L L
Sbjct: 336 QKNLKEKQRELKTARTLSL 354
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,902,566
Number of Sequences: 37866
Number of extensions: 828207
Number of successful extensions: 2215
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2112
Number of HSP's gapped (non-prelim): 93
length of query: 585
length of database: 18,247,518
effective HSP length: 108
effective length of query: 477
effective length of database: 14,157,990
effective search space: 6753361230
effective search space used: 6753361230
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.