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Search of human proteins with 170295802
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
(595 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 1214 0.0
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 1214 0.0
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 1214 0.0
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 1214 0.0
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens] 463 e-130
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens] 410 e-114
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens] 410 e-114
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 263 3e-70
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 263 3e-70
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 263 3e-70
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 263 3e-70
gi|238550159 estrogen-related receptor beta [Homo sapiens] 257 2e-68
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 243 3e-64
gi|110611914 progesterone receptor [Homo sapiens] 178 1e-44
gi|11415052 retinoid X receptor, beta [Homo sapiens] 176 7e-44
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 170 4e-42
gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Ho... 169 7e-42
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 166 4e-41
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof... 165 1e-40
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof... 165 1e-40
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof... 165 1e-40
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof... 165 1e-40
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo... 165 1e-40
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof... 164 2e-40
gi|21322252 androgen receptor isoform 1 [Homo sapiens] 162 6e-40
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom... 162 6e-40
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom... 162 6e-40
gi|66528677 nuclear receptor subfamily 3, group C, member 1 isof... 160 3e-39
gi|58535455 androgen receptor isoform 2 [Homo sapiens] 158 1e-38
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo... 155 8e-38
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 1214 bits (3141), Expect = 0.0
Identities = 595/595 (100%), Positives = 595/595 (100%)
Query: 1 MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
Sbjct: 1 MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
Query: 61 EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
Sbjct: 61 EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
Query: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
Sbjct: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
Query: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
Sbjct: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
Query: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
Sbjct: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
Query: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
Sbjct: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
Query: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
Sbjct: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
Query: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
Sbjct: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
Sbjct: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
Query: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
Sbjct: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 1214 bits (3141), Expect = 0.0
Identities = 595/595 (100%), Positives = 595/595 (100%)
Query: 1 MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
Sbjct: 1 MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
Query: 61 EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
Sbjct: 61 EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
Query: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
Sbjct: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
Query: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
Sbjct: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
Query: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
Sbjct: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
Query: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
Sbjct: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
Query: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
Sbjct: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
Query: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
Sbjct: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
Sbjct: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
Query: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
Sbjct: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 1214 bits (3141), Expect = 0.0
Identities = 595/595 (100%), Positives = 595/595 (100%)
Query: 1 MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
Sbjct: 1 MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
Query: 61 EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
Sbjct: 61 EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
Query: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
Sbjct: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
Query: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
Sbjct: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
Query: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
Sbjct: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
Query: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
Sbjct: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
Query: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
Sbjct: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
Query: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
Sbjct: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
Sbjct: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
Query: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
Sbjct: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 1214 bits (3141), Expect = 0.0
Identities = 595/595 (100%), Positives = 595/595 (100%)
Query: 1 MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
Sbjct: 1 MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
Query: 61 EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
Sbjct: 61 EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
Query: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
Sbjct: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
Query: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
Sbjct: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
Query: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
Sbjct: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
Query: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
Sbjct: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
Query: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
Sbjct: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
Query: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
Sbjct: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
Sbjct: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
Query: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
Sbjct: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
Length = 530
Score = 463 bits (1191), Expect = e-130
Identities = 260/536 (48%), Positives = 347/536 (64%), Gaps = 53/536 (9%)
Query: 21 NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
N N Q +PLE G +Y+ SS V ++ E A F + A N + T L
Sbjct: 11 NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
Query: 80 YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
GPG + SP +L P LSP L H Q Y E + S +
Sbjct: 67 GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
Query: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
+ +R+ R AS S ++ +CAVC+DYASGYHYGV
Sbjct: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
Query: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
Query: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
G R+++ +R D+ G+ + G A +R L +L+ +Q
Sbjct: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
Query: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
+V LL+AEPP +L S P+ PF+EASMM LT LAD+ELVHMI+WAK++PGFV+L+L
Sbjct: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
Query: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
DQV LLE W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
Query: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
RFR + LQ +E++C+K++ILLNS +Y +++T + + + +L+ +TD L+ ++AK+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
Query: 494 GLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRL 549
G++ QQQ RLA LL++LSH+RH SNKGMEHL +MKCKNVVP+YDLLLEML+AH L
Sbjct: 445 GISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVL 500
>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 410 bits (1055), Expect = e-114
Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)
Query: 21 NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
N N Q +PLE G +Y+ SS V ++ E A F + A N + T L
Sbjct: 11 NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
Query: 80 YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
GPG + SP +L P LSP L H Q Y E + S +
Sbjct: 67 GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
Query: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
+ +R+ R AS S ++ +CAVC+DYASGYHYGV
Sbjct: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
Query: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
Query: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
G R+++ +R D+ G+ + G A +R L +L+ +Q
Sbjct: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
Query: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
+V LL+AEPP +L S P+ PF+EASMM LT LAD+ELVHMI+WAK++PGFV+L+L
Sbjct: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
Query: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
DQV LLE W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
Query: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
RFR + LQ +E++C+K++ILLNS +Y +++T + + + +L+ +TD L+ ++AK+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
Query: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535
G++ QQQ RLA LL++LSH+RH + K + L + MK + ++P
Sbjct: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 410 bits (1055), Expect = e-114
Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)
Query: 21 NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
N N Q +PLE G +Y+ SS V ++ E A F + A N + T L
Sbjct: 11 NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66
Query: 80 YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
GPG + SP +L P LSP L H Q Y E + S +
Sbjct: 67 GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107
Query: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
+ +R+ R AS S ++ +CAVC+DYASGYHYGV
Sbjct: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163
Query: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223
Query: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
G R+++ +R D+ G+ + G A +R L +L+ +Q
Sbjct: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267
Query: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
+V LL+AEPP +L S P+ PF+EASMM LT LAD+ELVHMI+WAK++PGFV+L+L
Sbjct: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
Query: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
DQV LLE W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
Query: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
RFR + LQ +E++C+K++ILLNS +Y +++T + + + +L+ +TD L+ ++AK+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444
Query: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535
G++ QQQ RLA LL++LSH+RH + K + L + MK + ++P
Sbjct: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 263 bits (673), Expect = 3e-70
Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)
Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
M ++ R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 96 MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
SCQACR KC +VGM+K G+R DR RGGR K+KR R D E + + +
Sbjct: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
P +++ +KK +++VS LL AEP +Y+ DPT P S+ + L +LADREL
Sbjct: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
V +I WAK +PGF L+L DQ+ LL+ AW+EIL++G+V+RS+ +L++A + ++D +Q
Sbjct: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
K + G++++ + +L +++ M L+ EEFV LK+I L N S +E+ +
Sbjct: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
+ ++ D + + L A + + +R ++L+ L +R S K ++H Y++K + V
Sbjct: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
Query: 535 PLYDLLLEMLDA 546
P++ L LEML+A
Sbjct: 422 PMHKLFLEMLEA 433
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 263 bits (673), Expect = 3e-70
Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)
Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
M ++ R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 96 MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
SCQACR KC +VGM+K G+R DR RGGR K+KR R D E + + +
Sbjct: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
P +++ +KK +++VS LL AEP +Y+ DPT P S+ + L +LADREL
Sbjct: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
V +I WAK +PGF L+L DQ+ LL+ AW+EIL++G+V+RS+ +L++A + ++D +Q
Sbjct: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
K + G++++ + +L +++ M L+ EEFV LK+I L N S +E+ +
Sbjct: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
+ ++ D + + L A + + +R ++L+ L +R S K ++H Y++K + V
Sbjct: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
Query: 535 PLYDLLLEMLDA 546
P++ L LEML+A
Sbjct: 422 PMHKLFLEMLEA 433
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 263 bits (673), Expect = 3e-70
Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)
Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
M ++ R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 119 MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 178
Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
SCQACR KC +VGM+K G+R DR RGGR K+KR R D E + + +
Sbjct: 179 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 223
Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
P +++ +KK +++VS LL AEP +Y+ DPT P S+ + L +LADREL
Sbjct: 224 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 276
Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
V +I WAK +PGF L+L DQ+ LL+ AW+EIL++G+V+RS+ +L++A + ++D +Q
Sbjct: 277 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 336
Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
K + G++++ + +L +++ M L+ EEFV LK+I L N S +E+ +
Sbjct: 337 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 387
Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
+ ++ D + + L A + + +R ++L+ L +R S K ++H Y++K + V
Sbjct: 388 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 444
Query: 535 PLYDLLLEMLDA 546
P++ L LEML+A
Sbjct: 445 PMHKLFLEMLEA 456
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 263 bits (673), Expect = 3e-70
Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)
Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
M ++ R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 96 MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
SCQACR KC +VGM+K G+R DR RGGR K+KR R D E + + +
Sbjct: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
P +++ +KK +++VS LL AEP +Y+ DPT P S+ + L +LADREL
Sbjct: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
V +I WAK +PGF L+L DQ+ LL+ AW+EIL++G+V+RS+ +L++A + ++D +Q
Sbjct: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
K + G++++ + +L +++ M L+ EEFV LK+I L N S +E+ +
Sbjct: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
+ ++ D + + L A + + +R ++L+ L +R S K ++H Y++K + V
Sbjct: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
Query: 535 PLYDLLLEMLDA 546
P++ L LEML+A
Sbjct: 422 PMHKLFLEMLEA 433
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 257 bits (657), Expect = 2e-68
Identities = 156/375 (41%), Positives = 222/375 (59%), Gaps = 41/375 (10%)
Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
M +A R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 94 MLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 153
Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
SCQACR KC +VGM+K G+R DR RGGR K+KR+ D S
Sbjct: 154 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKRRLDSES------------------S 194
Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
P + S + S ++VS LL AEP LY+ P P + + L +LADREL
Sbjct: 195 PYL---SLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADREL 251
Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
V +I WAK +PGF L+L DQ+ LL+ AW+EIL++G+V+RS+ + KL++A + ++D
Sbjct: 252 VVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEH 311
Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
+ + G++E++ +L R++ + ++ EEFV LK++ L NS S ++ LE
Sbjct: 312 SR-LAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSD-----SMYIEDLE---- 361
Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQ---RLAQLLLILSHIRHMSNKGMEHLYSMKCK 531
+ K+ D L+H A L Q+H+ R +LLL L +R + K ++H YS+K +
Sbjct: 362 ---AVQKLQD-LLH-EALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQ 416
Query: 532 NVVPLYDLLLEMLDA 546
VP++ L LEML+A
Sbjct: 417 GKVPMHKLFLEMLEA 431
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 243 bits (621), Expect = 3e-64
Identities = 154/433 (35%), Positives = 227/433 (52%), Gaps = 37/433 (8%)
Query: 129 PYYLENEPS------GYTVREAGPPAFYRPNS-------DNRRQGGRERLASTNDKGSMA 175
P Y++ EP+ G + E PP P ++ + E G
Sbjct: 10 PLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKL 69
Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
+ S+ R C VC D ASGYHYGV SCE CKAFFKR+IQG +Y CPA+N+C I K RRK
Sbjct: 70 VLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRK 129
Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
+CQACR KC VGM+K G+R DR RGGR +R D + G A
Sbjct: 130 ACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVD-----PLPFPGPFPA-----G 179
Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
PL + + + A + +VS LL EP LY+ DP P + L +L DRE+
Sbjct: 180 PLAVAGGPRKTAA---PVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREI 236
Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
V I+WAK +PGF L+L DQ+ +L+ W+E+L++G+ RS+ +L FA +L+LD +
Sbjct: 237 VVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EE 295
Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
G G+ E+ LL R + + L+ EE+V LK++ L NS +E+ +
Sbjct: 296 GARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSV--------HIEDAEA 347
Query: 475 IHRVLDKITDTLIHLMA-KAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNV 533
+ ++ + + + L+ A +AG + +R +LLL L +R + K + H Y +K +
Sbjct: 348 VEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGK 407
Query: 534 VPLYDLLLEMLDA 546
VP++ L LEML+A
Sbjct: 408 VPMHKLFLEMLEA 420
>gi|110611914 progesterone receptor [Homo sapiens]
Length = 933
Score = 178 bits (452), Expect = 1e-44
Identities = 137/456 (30%), Positives = 223/456 (48%), Gaps = 72/456 (15%)
Query: 65 AAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPH 124
A A+ + + GLP S AAA G P L P + L+ PQL
Sbjct: 482 APGASGCLLPRDGLPSTSASAAAA------GAAPALY-----PALGLNGLPQL------- 523
Query: 125 GQQVPYYLENEPSGYTVREAGPPA--FYRPNSDNRRQGGRERLASTNDKGSMAMESAKET 182
G Q E P Y PP + RP+S+ + + ES +
Sbjct: 524 GYQAAVLKEGLPQVY------PPYLNYLRPDSE------------ASQSPQYSFESLPQ- 564
Query: 183 RYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRL 242
+ C +C D ASG HYGV +C CK FFKR+++G ++Y+C N C +DK RRK+C ACRL
Sbjct: 565 KICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRL 624
Query: 243 RKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMI-KRS 301
RKC + GM+ GG RK ++ ++ V A D A P P+ + S
Sbjct: 625 RKCCQAGMVLGG-RKFKKFNKV--------------RVVRALDAVAL---PQPVGVPNES 666
Query: 302 KKNSLALSLTADQ-------MVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
+ S + + Q +++ L+ EP ++Y+ +D T+P + +S++ L L +R+L
Sbjct: 667 QALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQL 726
Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEH-PGKLL-FAPNLLLDR 412
+ ++ W+K +PGF +L + DQ+ L++ +W+ +++ GL WRS +H G++L FAP+L+L+
Sbjct: 727 LSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNE 786
Query: 413 NQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEK 472
+ K + + F + + EEF+C+K ++LLN+ L S + E +
Sbjct: 787 QRMK-ESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMR 845
Query: 473 DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
R L K I L K ++ Q+ +L +LL
Sbjct: 846 SSYIRELIK----AIGLRQKGVVSSSQRFYQLTKLL 877
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 176 bits (445), Expect = 7e-44
Identities = 157/531 (29%), Positives = 223/531 (41%), Gaps = 89/531 (16%)
Query: 64 AAAAANAQVYGQTGLPYGPGSEAA--AFGSNGLGGFPPLNSVSPSPLMLLHPPPQ----- 116
AAAAA A G+ P EA G +G P +S SP+PL PPP
Sbjct: 46 AAAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSP-DSSSPNPLPQGVPPPSPPGPP 104
Query: 117 ----LSPFLQPHGQQVPYYLENEPSGYT------------VREAGPPAFYRPNSDNRRQG 160
+P L G P + P G + PP F P S +
Sbjct: 105 LPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINS 164
Query: 161 GRERLASTNDKGSMAMESAKET--------------------RYCAVCNDYASGYHYGVW 200
S GS E K R CA+C D +SG HYGV+
Sbjct: 165 ----TVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVY 220
Query: 201 SCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRR 260
SCEGCK FFKR+I+ Y C CT+DK +R CQ CR +KC GM + ++++R+
Sbjct: 221 SCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQ 280
Query: 261 GGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALL 320
G+ DG+G G G+ P + + R + LA+ +DQ V
Sbjct: 281 RGK-------DKDGDGEGAGGA----------PEEMPVDRILEAELAVEQKSDQGV---- 319
Query: 321 DAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLE 380
+ S P P + + AD++L ++ WAKR+P F L L DQV LL
Sbjct: 320 EGPGGTGGSGSSPNDPVTN------ICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLR 373
Query: 381 CAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLA-TSSRFRMMN 439
W E+L+ RS++ +L A L + RN G+ IFD +L S+ R M
Sbjct: 374 AGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSA-GVGAIFDRVLTELVSKMRDMR 432
Query: 440 LQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQ 499
+ E CL++IIL N K L + + +K+ +L + +
Sbjct: 433 MDKTELGCLRAIILFNPDA--------KGLSNPSEVEVLREKVYASLETYCKQ---KYPE 481
Query: 500 QHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDA-HRL 549
Q R A+LLL L +R + K +EHL+ K P+ L+EML+A H+L
Sbjct: 482 QQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQL 532
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 170 bits (430), Expect = 4e-42
Identities = 145/488 (29%), Positives = 218/488 (44%), Gaps = 52/488 (10%)
Query: 69 NAQVYGQTGLPYGPGSEAAAFGSNGLG---GFP-----PLNSVSPSPLMLLHPP-PQLSP 119
+ QV P G GS AA LG G P P++++S SP+ + PP +S
Sbjct: 12 STQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLS-SPINGMGPPFSVISS 70
Query: 120 FLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESA 179
+ PH VP S + + + P + D + G + S M S
Sbjct: 71 PMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASF 130
Query: 180 KETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQA 239
+ CA+C D +SG HYGV+SCEGCK FFKR+++ Y C C IDK +R CQ
Sbjct: 131 TK-HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 189
Query: 240 CRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIK 299
CR +KC +GM + ++++R+ G + R++ E + DM ++
Sbjct: 190 CRYQKCLAMGMKREAVQEERQRG------KDRNENEVESTSSANEDM----------PVE 233
Query: 300 RSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMIN 359
R + LA+ + V A + P S DP +A AD++L ++
Sbjct: 234 RILEAELAVEPKTETYVEANMGLNPS---SPNDPVTNICQA---------ADKQLFTLVE 281
Query: 360 WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVE 419
WAKR+P F +L L DQV LL W E+L+ RS+ +L A L + RN
Sbjct: 282 WAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA- 340
Query: 420 GMVEIFDMLLA-TSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRV 478
G+ IFD +L S+ R M + E CL++I+L N K L + +
Sbjct: 341 GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFN--------PDSKGLSNPAEVEAL 392
Query: 479 LDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYD 538
+K+ L A +Q R A+LLL L +R + K +EHL+ K P+
Sbjct: 393 REKV---YASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449
Query: 539 LLLEMLDA 546
L+EML+A
Sbjct: 450 FLMEMLEA 457
>gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Homo
sapiens]
Length = 984
Score = 169 bits (428), Expect = 7e-42
Identities = 109/375 (29%), Positives = 188/375 (50%), Gaps = 31/375 (8%)
Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
S++ S++ S++ ++ C VC D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 585 SSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRND 644
Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQ-------------RDD 273
C IDK RRK+C ACRL+KC + GM G + + G H+ Q +
Sbjct: 645 CIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSP 704
Query: 274 GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDP 333
EG + A + PS + ++++ +LT V L + EP I+Y+ YD
Sbjct: 705 EEGTTYIAPAKE-------PSVNTALVPQLSTISRALTPSP-VMVLENIEPEIVYAGYDS 756
Query: 334 TRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVW 393
++P + +++ L LA ++++ ++ WAK +PGF +L L DQ+ L++ +W+ + L W
Sbjct: 757 SKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSW 816
Query: 394 RSMEHPGK--LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSI 451
RS +H L FAP+L+ + + M E+ + S +F + L EE+ +K +
Sbjct: 817 RSYKHTNSQFLYFAPDLVFNEEK-MHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVL 875
Query: 452 ILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL 511
+LL++ L S E + + + L K ++ K Q QR QL +L
Sbjct: 876 LLLSTIPKDGLKSQAAFEEMRTNYIKELRK-------MVTKCPNNSGQSWQRFYQLTKLL 928
Query: 512 SHIRHMSNKGMEHLY 526
+ + + +E +
Sbjct: 929 DSMHDLVSDLLEFCF 943
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 166 bits (421), Expect = 4e-41
Identities = 115/365 (31%), Positives = 169/365 (46%), Gaps = 50/365 (13%)
Query: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
CA+C D +SG HYGV+SCEGCK FFKR+I+ Y C C IDK +R CQ CR +K
Sbjct: 139 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQK 198
Query: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
C +GM + ++++R +R R+ E E ++G
Sbjct: 199 CLVMGMKREAVQEER--------QRSRERAESEAECATSGH------------------- 231
Query: 305 SLALSLTADQMVSALLDAE---PPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWA 361
D V +L+AE P S D S + + + AD++L ++ WA
Sbjct: 232 -------EDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWA 284
Query: 362 KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGM 421
KR+P F DLTL DQV LL W E+L+ RS+ +L A L + R+ G+
Sbjct: 285 KRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSA-GV 343
Query: 422 VEIFDMLLA-TSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
IFD +L S+ + M + E CL++I+L N K L + + +
Sbjct: 344 GSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDA--------KGLSNPSEVETLRE 395
Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
K+ T L A +Q R A+LLL L +R + K +EHL+ K P+ L
Sbjct: 396 KVYAT---LEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL 452
Query: 541 LEMLD 545
+EML+
Sbjct: 453 MEMLE 457
>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 165 bits (417), Expect = 1e-40
Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)
Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
S+ S + + C VC+D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462
Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
C IDK RRK+C ACR RKC + GM + R+ + +K +Q G + + G+
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518
Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
L +VS L EP +LY+ YD + P S +M L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563
Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
L R+++ + WAK +PGF +L L DQ+ LL+ +W+ ++ L WRS L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623
Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
AP+L+++ Q + M + +L SS + + EE++C+K+++LL+S
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678
Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
LKS E + D+I T I + KA + + Q QR QL +L + +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728
>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 165 bits (417), Expect = 1e-40
Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)
Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
S+ S + + C VC+D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462
Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
C IDK RRK+C ACR RKC + GM + R+ + +K +Q G + + G+
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518
Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
L +VS L EP +LY+ YD + P S +M L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563
Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
L R+++ + WAK +PGF +L L DQ+ LL+ +W+ ++ L WRS L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623
Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
AP+L+++ Q + M + +L SS + + EE++C+K+++LL+S
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678
Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
LKS E + D+I T I + KA + + Q QR QL +L + +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728
>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 165 bits (417), Expect = 1e-40
Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)
Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
S+ S + + C VC+D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462
Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
C IDK RRK+C ACR RKC + GM + R+ + +K +Q G + + G+
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518
Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
L +VS L EP +LY+ YD + P S +M L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563
Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
L R+++ + WAK +PGF +L L DQ+ LL+ +W+ ++ L WRS L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623
Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
AP+L+++ Q + M + +L SS + + EE++C+K+++LL+S
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678
Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
LKS E + D+I T I + KA + + Q QR QL +L + +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728
>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 165 bits (417), Expect = 1e-40
Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)
Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
S+ S + + C VC+D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462
Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
C IDK RRK+C ACR RKC + GM + R+ + +K +Q G + + G+
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518
Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
L +VS L EP +LY+ YD + P S +M L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563
Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
L R+++ + WAK +PGF +L L DQ+ LL+ +W+ ++ L WRS L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623
Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
AP+L+++ Q + M + +L SS + + EE++C+K+++LL+S
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678
Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
LKS E + D+I T I + KA + + Q QR QL +L + +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728
>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 165 bits (417), Expect = 1e-40
Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)
Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
S+ S + + C VC+D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462
Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
C IDK RRK+C ACR RKC + GM + R+ + +K +Q G + + G+
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518
Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
L +VS L EP +LY+ YD + P S +M L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563
Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
L R+++ + WAK +PGF +L L DQ+ LL+ +W+ ++ L WRS L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623
Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
AP+L+++ Q + M + +L SS + + EE++C+K+++LL+S
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678
Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
LKS E + D+I T I + KA + + Q QR QL +L + +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728
>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
beta [Homo sapiens]
Length = 742
Score = 164 bits (416), Expect = 2e-40
Identities = 111/351 (31%), Positives = 171/351 (48%), Gaps = 37/351 (10%)
Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
S+ S + + C VC+D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462
Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
C IDK RRK+C ACR RKC + GM + R+ + +K +Q G + + G+
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518
Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
L +VS L EP +LY+ YD + P S +M L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563
Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
L R+++ + WAK +PGF +L L DQ+ LL+ +W+ ++ L WRS L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623
Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
AP+L+++ Q + M + +L SS + + EE++C+K+++LL+S
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678
Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLIL 511
LKS E + D+I T I + KA + + Q QR QL +L
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLL 722
>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
Length = 920
Score = 162 bits (411), Expect = 6e-40
Identities = 128/465 (27%), Positives = 209/465 (44%), Gaps = 64/465 (13%)
Query: 67 AANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQL----SPFLQ 122
A Q+YG G G G G G GG + + +P PP L S F
Sbjct: 441 AEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGG-EAGAVAPYGYTRPPQGLAGQESDFTA 499
Query: 123 PHG-------QQVPYYLENEPSGYTVR-EAGP--PAFYRPNSDNRRQGGRERLASTNDKG 172
P +VPY PS V+ E GP ++ P D R + R+ + +
Sbjct: 500 PDVWYPGGMVSRVPY-----PSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPID--- 551
Query: 173 SMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKN 232
+ C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK
Sbjct: 552 ----YYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKF 607
Query: 233 RRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLW 292
RRK+C +CRLRKCYE GM G + + G L+ + GE S
Sbjct: 608 RRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS------- 651
Query: 293 PSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR 352
P+ ++ + + ++ L EP ++ + +D +P S A+++ L L +R
Sbjct: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711
Query: 353 ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLL 410
+LVH++ WAK +PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+
Sbjct: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771
Query: 411 D-------RNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLS 463
+ R +CV + S F + + +EF+C+K+++L +
Sbjct: 772 NEYRMHKSRMYSQCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPV 819
Query: 464 STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
LK+ + D + K D +I K + ++ +L +LL
Sbjct: 820 DGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 864
>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 162 bits (411), Expect = 6e-40
Identities = 151/539 (28%), Positives = 230/539 (42%), Gaps = 109/539 (20%)
Query: 55 PEGAAYEFNAAAAANAQVYG-QTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHP 113
P A+++F + QVYG G GP EA + + G P +PSP
Sbjct: 96 PASASFKFE-----DFQVYGCYPGPLSGPVDEALSSSGSDYYGSP---CSAPSPSTPSFQ 147
Query: 114 PPQLSPF---------------LQPHGQQVP----------YYLENEPSGYTVREAGPPA 148
PPQLSP+ L+ +Q+P ++ + P+G + A P
Sbjct: 148 PPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPL 207
Query: 149 FYRPNSDNRRQGGRERLAS------------------------TNDKGSMAMESAKETRY 184
P+ + G E + T+ K E R
Sbjct: 208 KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGR- 266
Query: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
CAVC D AS HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326
Query: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
C VGM+K +R D GR RG + P K+
Sbjct: 327 CLAVGMVKEVVRTDSLKGR-------------RGRL--------------PSKPKQPPDA 359
Query: 305 SLALSLTADQMVSALLDAEPPILYSEYD-------PTRPFSEASMMGLLTNLADRELVHM 357
S A LT+ +V A LD+ P +Y P +A + +L L +
Sbjct: 360 SPANLLTS--LVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVI 417
Query: 358 INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKC 417
WA+++PGF +L+ DQ LLE A+LE+ ++ L +RS GKL+F L+L R Q C
Sbjct: 418 RKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--C 475
Query: 418 VEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHR 477
G + D +LA S + + F CL +++L+ + L+E +
Sbjct: 476 ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI---------TDRHGLQEPRRVEE 526
Query: 478 VLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVP 535
+ ++I L H+ A AG Q L++LL L +R + +G++ ++ +K +++VP
Sbjct: 527 LQNRIASCLKEHVAAVAG--EPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583
>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
sapiens]
Length = 598
Score = 162 bits (411), Expect = 6e-40
Identities = 151/539 (28%), Positives = 230/539 (42%), Gaps = 109/539 (20%)
Query: 55 PEGAAYEFNAAAAANAQVYG-QTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHP 113
P A+++F + QVYG G GP EA + + G P +PSP
Sbjct: 96 PASASFKFE-----DFQVYGCYPGPLSGPVDEALSSSGSDYYGSP---CSAPSPSTPSFQ 147
Query: 114 PPQLSPF---------------LQPHGQQVP----------YYLENEPSGYTVREAGPPA 148
PPQLSP+ L+ +Q+P ++ + P+G + A P
Sbjct: 148 PPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPL 207
Query: 149 FYRPNSDNRRQGGRERLAS------------------------TNDKGSMAMESAKETRY 184
P+ + G E + T+ K E R
Sbjct: 208 KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGR- 266
Query: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
CAVC D AS HYGV +CEGCK FFKR++Q + Y+C A C +DK RR CQ CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326
Query: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
C VGM+K +R D GR RG + P K+
Sbjct: 327 CLAVGMVKEVVRTDSLKGR-------------RGRL--------------PSKPKQPPDA 359
Query: 305 SLALSLTADQMVSALLDAEPPILYSEYD-------PTRPFSEASMMGLLTNLADRELVHM 357
S A LT+ +V A LD+ P +Y P +A + +L L +
Sbjct: 360 SPANLLTS--LVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVI 417
Query: 358 INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKC 417
WA+++PGF +L+ DQ LLE A+LE+ ++ L +RS GKL+F L+L R Q C
Sbjct: 418 RKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--C 475
Query: 418 VEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHR 477
G + D +LA S + + F CL +++L+ + L+E +
Sbjct: 476 ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI---------TDRHGLQEPRRVEE 526
Query: 478 VLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVP 535
+ ++I L H+ A AG Q L++LL L +R + +G++ ++ +K +++VP
Sbjct: 527 LQNRIASCLKEHVAAVAG--EPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583
>gi|66528677 nuclear receptor subfamily 3, group C, member 1 isoform
gamma [Homo sapiens]
Length = 778
Score = 160 bits (405), Expect = 3e-39
Identities = 111/358 (31%), Positives = 173/358 (48%), Gaps = 38/358 (10%)
Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGH-NDYMCPATN 225
S+ S + + C VC+D ASG HYGV +C CK FFKR+++G ++Y+C N
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGRQHNYLCAGRN 462
Query: 226 QCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGD 285
C IDK RRK+C ACR RKC + GM + R+ + +K +Q G + + G+
Sbjct: 463 DCIIDKIRRKNCPACRYRKCLQAGMNL----EARKTKKKIKGIQQATTGVSQETSENPGN 518
Query: 286 MRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGL 345
L +VS L EP +LY+ YD + P S +M
Sbjct: 519 KTIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTT 563
Query: 346 LTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LL 403
L L R+++ + WAK +PGF +L L DQ+ LL+ +W+ ++ L WRS L
Sbjct: 564 LNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLC 623
Query: 404 FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLS 463
FAP+L+++ Q + M + +L SS + + EE++C+K+++LL+S
Sbjct: 624 FAPDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPK 678
Query: 464 STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
LKS E + D+I T I + KA + + Q QR QL +L + +
Sbjct: 679 DGLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 729
>gi|58535455 androgen receptor isoform 2 [Homo sapiens]
Length = 388
Score = 158 bits (400), Expect = 1e-38
Identities = 97/333 (29%), Positives = 165/333 (49%), Gaps = 37/333 (11%)
Query: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
C +C D ASG HYG +C CK FFKR+ +G Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 28 CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87
Query: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
CYE GM G + + G L+ + GE S P+ ++ +
Sbjct: 88 CYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS-------PTEETTQKLTVS 131
Query: 305 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRV 364
+ ++ L EP ++ + +D +P S A+++ L L +R+LVH++ WAK +
Sbjct: 132 HIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKAL 191
Query: 365 PGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLLD-------RNQG 415
PGF +L + DQ+ +++ +W+ +++ + WRS + L FAP+L+ + R
Sbjct: 192 PGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYS 251
Query: 416 KCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHI 475
+CV + S F + + +EF+C+K+++L + LK+ + D +
Sbjct: 252 QCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPVDGLKNQKFFDEL 299
Query: 476 HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
K D +I K + ++ +L +LL
Sbjct: 300 RMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 332
>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
sapiens]
Length = 598
Score = 155 bits (393), Expect = 8e-38
Identities = 114/384 (29%), Positives = 181/384 (47%), Gaps = 46/384 (11%)
Query: 160 GGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDY 219
G +L T + S CAVC D A+ HYGV +CEGCK FFKR++Q + Y
Sbjct: 238 GHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKY 297
Query: 220 MCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGE 279
+C A C +DK RR CQ CR +KC VGM+K +R D GR RG
Sbjct: 298 VCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGR-------------RGR 344
Query: 280 VGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSE 339
+ S PSP +SL + +V A +D+ P + +Y + +
Sbjct: 345 LPSKPKSPQEPSPPSP-----------PVSLIS-ALVRAHVDSNPAMTSLDYSRFQANPD 392
Query: 340 ASMMGLLT-------NLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLV 392
M G T +L + + WA+++PGF DL DQ L E A+LE+ ++ L
Sbjct: 393 YQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLA 452
Query: 393 WRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII 452
+RS GKL+F ++L R Q CV G E D ++ SS + MN+ F C+ ++
Sbjct: 453 YRSNPVEGKLIFCNGVVLHRLQ--CVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALA 510
Query: 453 LLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLIL 511
++ + L+E + + +KI + L H+ G + + L++LL L
Sbjct: 511 MV---------TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNY--LSKLLGKL 559
Query: 512 SHIRHMSNKGMEHLYSMKCKNVVP 535
+R + +G++ ++ +K +++VP
Sbjct: 560 PELRTLCTQGLQRIFYLKLEDLVP 583
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,780,357
Number of Sequences: 37866
Number of extensions: 1250506
Number of successful extensions: 4268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 3916
Number of HSP's gapped (non-prelim): 291
length of query: 595
length of database: 18,247,518
effective HSP length: 108
effective length of query: 487
effective length of database: 14,157,990
effective search space: 6894941130
effective search space used: 6894941130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.