Guide to the Human Genome
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Search of human proteins with 170295800

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
         (595 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]        1214   0.0  
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]        1214   0.0  
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]        1214   0.0  
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]         1214   0.0  
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]           463   e-130
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]           410   e-114
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]           410   e-114
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi...   263   3e-70
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi...   263   3e-70
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi...   263   3e-70
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap...   263   3e-70
gi|238550159 estrogen-related receptor beta [Homo sapiens]            257   2e-68
gi|18860920 estrogen-related receptor alpha [Homo sapiens]            243   3e-64
gi|110611914 progesterone receptor [Homo sapiens]                     178   1e-44
gi|11415052 retinoid X receptor, beta [Homo sapiens]                  176   7e-44
gi|4506755 retinoid X receptor, alpha [Homo sapiens]                  170   4e-42
gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Ho...   169   7e-42
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]        166   4e-41
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof...   165   1e-40
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof...   165   1e-40
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof...   165   1e-40
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof...   165   1e-40
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo...   165   1e-40
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof...   164   2e-40
gi|21322252 androgen receptor isoform 1 [Homo sapiens]                162   6e-40
gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Hom...   162   6e-40
gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Hom...   162   6e-40
gi|66528677 nuclear receptor subfamily 3, group C, member 1 isof...   160   3e-39
gi|58535455 androgen receptor isoform 2 [Homo sapiens]                158   1e-38
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo...   155   8e-38

>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
          Length = 595

 Score = 1214 bits (3141), Expect = 0.0
 Identities = 595/595 (100%), Positives = 595/595 (100%)

Query: 1   MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
           MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
Sbjct: 1   MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60

Query: 61  EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
           EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
Sbjct: 61  EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120

Query: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
           LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
Sbjct: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180

Query: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
           ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
Sbjct: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240

Query: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
           RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
Sbjct: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300

Query: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
           SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
Sbjct: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360

Query: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
           AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
Sbjct: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420

Query: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
           MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
Sbjct: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480

Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
           KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
Sbjct: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540

Query: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
           LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
Sbjct: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595


>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
          Length = 595

 Score = 1214 bits (3141), Expect = 0.0
 Identities = 595/595 (100%), Positives = 595/595 (100%)

Query: 1   MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
           MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
Sbjct: 1   MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60

Query: 61  EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
           EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
Sbjct: 61  EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120

Query: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
           LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
Sbjct: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180

Query: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
           ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
Sbjct: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240

Query: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
           RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
Sbjct: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300

Query: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
           SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
Sbjct: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360

Query: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
           AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
Sbjct: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420

Query: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
           MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
Sbjct: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480

Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
           KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
Sbjct: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540

Query: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
           LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
Sbjct: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595


>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
          Length = 595

 Score = 1214 bits (3141), Expect = 0.0
 Identities = 595/595 (100%), Positives = 595/595 (100%)

Query: 1   MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
           MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
Sbjct: 1   MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60

Query: 61  EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
           EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
Sbjct: 61  EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120

Query: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
           LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
Sbjct: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180

Query: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
           ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
Sbjct: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240

Query: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
           RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
Sbjct: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300

Query: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
           SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
Sbjct: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360

Query: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
           AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
Sbjct: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420

Query: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
           MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
Sbjct: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480

Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
           KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
Sbjct: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540

Query: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
           LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
Sbjct: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595


>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
          Length = 595

 Score = 1214 bits (3141), Expect = 0.0
 Identities = 595/595 (100%), Positives = 595/595 (100%)

Query: 1   MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60
           MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY
Sbjct: 1   MTMTLHTKASGMALLHQIQGNELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAY 60

Query: 61  EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120
           EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF
Sbjct: 61  EFNAAAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPF 120

Query: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180
           LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK
Sbjct: 121 LQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAK 180

Query: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240
           ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC
Sbjct: 181 ETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQAC 240

Query: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300
           RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR
Sbjct: 241 RLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKR 300

Query: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360
           SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW
Sbjct: 301 SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINW 360

Query: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420
           AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG
Sbjct: 361 AKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEG 420

Query: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
           MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD
Sbjct: 421 MVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480

Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
           KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
Sbjct: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540

Query: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595
           LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV
Sbjct: 541 LEMLDAHRLHAPTSRGGASVEETDQSHLATAGSTSSHSLQKYYITGEAEGFPATV 595


>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
          Length = 530

 Score =  463 bits (1191), Expect = e-130
 Identities = 260/536 (48%), Positives = 347/536 (64%), Gaps = 53/536 (9%)

Query: 21  NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
           N     N  Q  +PLE   G +Y+ SS   V ++ E  A  F + A  N  +    T L 
Sbjct: 11  NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66

Query: 80  YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
            GPG +                    SP +L   P  LSP L  H Q    Y E + S +
Sbjct: 67  GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107

Query: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
               +            +R+    R AS          S ++  +CAVC+DYASGYHYGV
Sbjct: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163

Query: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
           WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223

Query: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
            G R+++ +R  D+     G+ +   G A  +R                  L  +L+ +Q
Sbjct: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267

Query: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
           +V  LL+AEPP +L S   P+ PF+EASMM  LT LAD+ELVHMI+WAK++PGFV+L+L 
Sbjct: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325

Query: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
           DQV LLE  W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385

Query: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
           RFR + LQ +E++C+K++ILLNS +Y  +++T +  +    +  +L+ +TD L+ ++AK+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444

Query: 494 GLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRL 549
           G++ QQQ  RLA LL++LSH+RH SNKGMEHL +MKCKNVVP+YDLLLEML+AH L
Sbjct: 445 GISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHVL 500


>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
          Length = 495

 Score =  410 bits (1055), Expect = e-114
 Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)

Query: 21  NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
           N     N  Q  +PLE   G +Y+ SS   V ++ E  A  F + A  N  +    T L 
Sbjct: 11  NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66

Query: 80  YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
            GPG +                    SP +L   P  LSP L  H Q    Y E + S +
Sbjct: 67  GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107

Query: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
               +            +R+    R AS          S ++  +CAVC+DYASGYHYGV
Sbjct: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163

Query: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
           WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223

Query: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
            G R+++ +R  D+     G+ +   G A  +R                  L  +L+ +Q
Sbjct: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267

Query: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
           +V  LL+AEPP +L S   P+ PF+EASMM  LT LAD+ELVHMI+WAK++PGFV+L+L 
Sbjct: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325

Query: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
           DQV LLE  W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385

Query: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
           RFR + LQ +E++C+K++ILLNS +Y  +++T +  +    +  +L+ +TD L+ ++AK+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444

Query: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535
           G++ QQQ  RLA LL++LSH+RH  + K  + L  + MK + ++P
Sbjct: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489


>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
          Length = 495

 Score =  410 bits (1055), Expect = e-114
 Identities = 238/525 (45%), Positives = 328/525 (62%), Gaps = 56/525 (10%)

Query: 21  NELEPLNRPQLKIPLERPLGEVYLDSSKPAVYNYPEGAAYEFNAAAAANAQVYGQ-TGLP 79
           N     N  Q  +PLE   G +Y+ SS   V ++ E  A  F + A  N  +    T L 
Sbjct: 11  NSPSSYNCSQSILPLEH--GSIYIPSSY--VDSHHEYPAMTFYSPAVMNYSIPSNVTNLE 66

Query: 80  YGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPHGQQVPYYLENEPSGY 139
            GPG +                    SP +L   P  LSP L  H Q    Y E + S +
Sbjct: 67  GGPGRQTT------------------SPNVLWPTPGHLSP-LVVHRQLSHLYAEPQKSPW 107

Query: 140 TVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGV 199
               +            +R+    R AS          S ++  +CAVC+DYASGYHYGV
Sbjct: 108 CEARSLEHTLPVNRETLKRKVSGNRCASP----VTGPGSKRDAHFCAVCSDYASGYHYGV 163

Query: 200 WSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDR 259
           WSCEGCKAFFKRSIQGHNDY+CPATNQCTIDKNRRKSCQACRLRKCYEVGM+K G R++R
Sbjct: 164 WSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRKCYEVGMVKCGSRRER 223

Query: 260 RGGRMLKHKRQRDD-----GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQ 314
            G R+++ +R  D+     G+ +   G A  +R                  L  +L+ +Q
Sbjct: 224 CGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVREL----------------LLDALSPEQ 267

Query: 315 MVSALLDAEPP-ILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLH 373
           +V  LL+AEPP +L S   P+ PF+EASMM  LT LAD+ELVHMI+WAK++PGFV+L+L 
Sbjct: 268 LVLTLLEAEPPHVLISR--PSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325

Query: 374 DQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSS 433
           DQV LLE  W+E+LM+GL+WRS++HPGKL+FAP+L+LDR++GKCVEG++EIFDMLLAT+S
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385

Query: 434 RFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKA 493
           RFR + LQ +E++C+K++ILLNS +Y  +++T +  +    +  +L+ +TD L+ ++AK+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTAT-QDADSSRKLAHLLNAVTDALVWVIAKS 444

Query: 494 GLTLQQQHQRLAQLLLILSHIRH-MSNKGMEHL--YSMKCKNVVP 535
           G++ QQQ  RLA LL++LSH+RH  + K  + L  + MK + ++P
Sbjct: 445 GISSQQQSMRLANLLMLLSHVRHARAEKASQTLTSFGMKMETLLP 489


>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  263 bits (673), Expect = 3e-70
 Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)

Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
           M ++   R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 96  MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155

Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
           SCQACR  KC +VGM+K G+R DR RGGR  K+KR R D E              + + +
Sbjct: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200

Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
           P +++ +KK         +++VS LL AEP  +Y+  DPT P S+   +  L +LADREL
Sbjct: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253

Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
           V +I WAK +PGF  L+L DQ+ LL+ AW+EIL++G+V+RS+    +L++A + ++D +Q
Sbjct: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313

Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
            K + G++++ + +L    +++ M L+ EEFV LK+I L N        S    +E+ + 
Sbjct: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364

Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
           + ++ D + + L    A   +   +  +R  ++L+ L  +R  S K ++H Y++K +  V
Sbjct: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421

Query: 535 PLYDLLLEMLDA 546
           P++ L LEML+A
Sbjct: 422 PMHKLFLEMLEA 433


>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  263 bits (673), Expect = 3e-70
 Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)

Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
           M ++   R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 96  MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155

Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
           SCQACR  KC +VGM+K G+R DR RGGR  K+KR R D E              + + +
Sbjct: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200

Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
           P +++ +KK         +++VS LL AEP  +Y+  DPT P S+   +  L +LADREL
Sbjct: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253

Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
           V +I WAK +PGF  L+L DQ+ LL+ AW+EIL++G+V+RS+    +L++A + ++D +Q
Sbjct: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313

Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
            K + G++++ + +L    +++ M L+ EEFV LK+I L N        S    +E+ + 
Sbjct: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364

Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
           + ++ D + + L    A   +   +  +R  ++L+ L  +R  S K ++H Y++K +  V
Sbjct: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421

Query: 535 PLYDLLLEMLDA 546
           P++ L LEML+A
Sbjct: 422 PMHKLFLEMLEA 433


>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
           sapiens]
          Length = 458

 Score =  263 bits (673), Expect = 3e-70
 Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)

Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
           M ++   R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 119 MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 178

Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
           SCQACR  KC +VGM+K G+R DR RGGR  K+KR R D E              + + +
Sbjct: 179 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 223

Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
           P +++ +KK         +++VS LL AEP  +Y+  DPT P S+   +  L +LADREL
Sbjct: 224 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 276

Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
           V +I WAK +PGF  L+L DQ+ LL+ AW+EIL++G+V+RS+    +L++A + ++D +Q
Sbjct: 277 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 336

Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
            K + G++++ + +L    +++ M L+ EEFV LK+I L N        S    +E+ + 
Sbjct: 337 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 387

Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
           + ++ D + + L    A   +   +  +R  ++L+ L  +R  S K ++H Y++K +  V
Sbjct: 388 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 444

Query: 535 PLYDLLLEMLDA 546
           P++ L LEML+A
Sbjct: 445 PMHKLFLEMLEA 456


>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  263 bits (673), Expect = 3e-70
 Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)

Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
           M ++   R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 96  MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155

Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
           SCQACR  KC +VGM+K G+R DR RGGR  K+KR R D E              + + +
Sbjct: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200

Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
           P +++ +KK         +++VS LL AEP  +Y+  DPT P S+   +  L +LADREL
Sbjct: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253

Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
           V +I WAK +PGF  L+L DQ+ LL+ AW+EIL++G+V+RS+    +L++A + ++D +Q
Sbjct: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313

Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
            K + G++++ + +L    +++ M L+ EEFV LK+I L N        S    +E+ + 
Sbjct: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364

Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
           + ++ D + + L    A   +   +  +R  ++L+ L  +R  S K ++H Y++K +  V
Sbjct: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421

Query: 535 PLYDLLLEMLDA 546
           P++ L LEML+A
Sbjct: 422 PMHKLFLEMLEA 433


>gi|238550159 estrogen-related receptor beta [Homo sapiens]
          Length = 508

 Score =  257 bits (657), Expect = 2e-68
 Identities = 156/375 (41%), Positives = 222/375 (59%), Gaps = 41/375 (10%)

Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
           M +A   R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 94  MLNAIPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 153

Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
           SCQACR  KC +VGM+K G+R DR RGGR  K+KR+ D                     S
Sbjct: 154 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKRRLDSES------------------S 194

Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
           P +   S + S        ++VS LL AEP  LY+   P  P  +   +  L +LADREL
Sbjct: 195 PYL---SLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIKALTTLCDLADREL 251

Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
           V +I WAK +PGF  L+L DQ+ LL+ AW+EIL++G+V+RS+ +  KL++A + ++D   
Sbjct: 252 VVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDKLVYAEDYIMDEEH 311

Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
            + + G++E++  +L    R++ + ++ EEFV LK++ L NS      S  ++ LE    
Sbjct: 312 SR-LAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSD-----SMYIEDLE---- 361

Query: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQ---RLAQLLLILSHIRHMSNKGMEHLYSMKCK 531
               + K+ D L+H  A     L Q+H+   R  +LLL L  +R  + K ++H YS+K +
Sbjct: 362 ---AVQKLQD-LLH-EALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQ 416

Query: 532 NVVPLYDLLLEMLDA 546
             VP++ L LEML+A
Sbjct: 417 GKVPMHKLFLEMLEA 431


>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
          Length = 423

 Score =  243 bits (621), Expect = 3e-64
 Identities = 154/433 (35%), Positives = 227/433 (52%), Gaps = 37/433 (8%)

Query: 129 PYYLENEPS------GYTVREAGPPAFYRPNS-------DNRRQGGRERLASTNDKGSMA 175
           P Y++ EP+      G +  E  PP    P          ++ +   E        G   
Sbjct: 10  PLYIKAEPASPDSPKGSSETETEPPVALAPGPAPTRCLPGHKEEEDGEGAGPGEQGGGKL 69

Query: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
           + S+   R C VC D ASGYHYGV SCE CKAFFKR+IQG  +Y CPA+N+C I K RRK
Sbjct: 70  VLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFKRTIQGSIEYSCPASNECEITKRRRK 129

Query: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
           +CQACR  KC  VGM+K G+R DR RGGR    +R   D      +   G   A      
Sbjct: 130 ACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRRPEVD-----PLPFPGPFPA-----G 179

Query: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
           PL +    + + A     + +VS LL  EP  LY+  DP  P      +  L +L DRE+
Sbjct: 180 PLAVAGGPRKTAA---PVNALVSHLLVVEPEKLYAMPDPAGPDGHLPAVATLCDLFDREI 236

Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
           V  I+WAK +PGF  L+L DQ+ +L+  W+E+L++G+  RS+    +L FA +L+LD  +
Sbjct: 237 VVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDELAFAEDLVLD-EE 295

Query: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
           G    G+ E+   LL    R + + L+ EE+V LK++ L NS            +E+ + 
Sbjct: 296 GARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSV--------HIEDAEA 347

Query: 475 IHRVLDKITDTLIHLMA-KAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNV 533
           + ++ + + + L+   A +AG     + +R  +LLL L  +R  + K + H Y +K +  
Sbjct: 348 VEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKLEGK 407

Query: 534 VPLYDLLLEMLDA 546
           VP++ L LEML+A
Sbjct: 408 VPMHKLFLEMLEA 420


>gi|110611914 progesterone receptor [Homo sapiens]
          Length = 933

 Score =  178 bits (452), Expect = 1e-44
 Identities = 137/456 (30%), Positives = 223/456 (48%), Gaps = 72/456 (15%)

Query: 65  AAAANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQLSPFLQPH 124
           A  A+  +  + GLP    S AAA      G  P L      P + L+  PQL       
Sbjct: 482 APGASGCLLPRDGLPSTSASAAAA------GAAPALY-----PALGLNGLPQL------- 523

Query: 125 GQQVPYYLENEPSGYTVREAGPPA--FYRPNSDNRRQGGRERLASTNDKGSMAMESAKET 182
           G Q     E  P  Y      PP   + RP+S+             +     + ES  + 
Sbjct: 524 GYQAAVLKEGLPQVY------PPYLNYLRPDSE------------ASQSPQYSFESLPQ- 564

Query: 183 RYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRL 242
           + C +C D ASG HYGV +C  CK FFKR+++G ++Y+C   N C +DK RRK+C ACRL
Sbjct: 565 KICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRL 624

Query: 243 RKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMI-KRS 301
           RKC + GM+ GG RK ++  ++               V  A D  A    P P+ +   S
Sbjct: 625 RKCCQAGMVLGG-RKFKKFNKV--------------RVVRALDAVAL---PQPVGVPNES 666

Query: 302 KKNSLALSLTADQ-------MVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
           +  S   + +  Q       +++ L+  EP ++Y+ +D T+P + +S++  L  L +R+L
Sbjct: 667 QALSQRFTFSPGQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQL 726

Query: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEH-PGKLL-FAPNLLLDR 412
           + ++ W+K +PGF +L + DQ+ L++ +W+ +++ GL WRS +H  G++L FAP+L+L+ 
Sbjct: 727 LSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNE 786

Query: 413 NQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEK 472
            + K       +   +      F  + +  EEF+C+K ++LLN+     L S  +  E +
Sbjct: 787 QRMK-ESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQTQFEEMR 845

Query: 473 DHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
               R L K     I L  K  ++  Q+  +L +LL
Sbjct: 846 SSYIRELIK----AIGLRQKGVVSSSQRFYQLTKLL 877


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score =  176 bits (445), Expect = 7e-44
 Identities = 157/531 (29%), Positives = 223/531 (41%), Gaps = 89/531 (16%)

Query: 64  AAAAANAQVYGQTGLPYGPGSEAA--AFGSNGLGGFPPLNSVSPSPLMLLHPPPQ----- 116
           AAAAA A   G+   P     EA     G +G     P +S SP+PL    PPP      
Sbjct: 46  AAAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSP-DSSSPNPLPQGVPPPSPPGPP 104

Query: 117 ----LSPFLQPHGQQVPYYLENEPSGYT------------VREAGPPAFYRPNSDNRRQG 160
                +P L   G   P  +   P G              +    PP F  P S  +   
Sbjct: 105 LPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGLPPPAPPGFSGPVSSPQINS 164

Query: 161 GRERLASTNDKGSMAMESAKET--------------------RYCAVCNDYASGYHYGVW 200
                 S    GS   E  K                      R CA+C D +SG HYGV+
Sbjct: 165 ----TVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAGKRLCAICGDRSSGKHYGVY 220

Query: 201 SCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRR 260
           SCEGCK FFKR+I+    Y C     CT+DK +R  CQ CR +KC   GM +  ++++R+
Sbjct: 221 SCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMKREAVQEERQ 280

Query: 261 GGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALL 320
            G+         DG+G G  G+          P  + + R  +  LA+   +DQ V    
Sbjct: 281 RGK-------DKDGDGEGAGGA----------PEEMPVDRILEAELAVEQKSDQGV---- 319

Query: 321 DAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLE 380
           +       S   P  P +       +   AD++L  ++ WAKR+P F  L L DQV LL 
Sbjct: 320 EGPGGTGGSGSSPNDPVTN------ICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLR 373

Query: 381 CAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLA-TSSRFRMMN 439
             W E+L+     RS++    +L A  L + RN      G+  IFD +L    S+ R M 
Sbjct: 374 AGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSA-GVGAIFDRVLTELVSKMRDMR 432

Query: 440 LQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQ 499
           +   E  CL++IIL N           K L     +  + +K+  +L     +      +
Sbjct: 433 MDKTELGCLRAIILFNPDA--------KGLSNPSEVEVLREKVYASLETYCKQ---KYPE 481

Query: 500 QHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDA-HRL 549
           Q  R A+LLL L  +R +  K +EHL+  K     P+   L+EML+A H+L
Sbjct: 482 QQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQL 532


>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
          Length = 462

 Score =  170 bits (430), Expect = 4e-42
 Identities = 145/488 (29%), Positives = 218/488 (44%), Gaps = 52/488 (10%)

Query: 69  NAQVYGQTGLPYGPGSEAAAFGSNGLG---GFP-----PLNSVSPSPLMLLHPP-PQLSP 119
           + QV      P G GS AA      LG   G P     P++++S SP+  + PP   +S 
Sbjct: 12  STQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLS-SPINGMGPPFSVISS 70

Query: 120 FLQPHGQQVPYYLENEPSGYTVREAGPPAFYRPNSDNRRQGGRERLASTNDKGSMAMESA 179
            + PH   VP       S  + + + P      + D +   G   +       S  M S 
Sbjct: 71  PMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASF 130

Query: 180 KETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQA 239
            +   CA+C D +SG HYGV+SCEGCK FFKR+++    Y C     C IDK +R  CQ 
Sbjct: 131 TK-HICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQY 189

Query: 240 CRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIK 299
           CR +KC  +GM +  ++++R+ G      + R++ E      +  DM           ++
Sbjct: 190 CRYQKCLAMGMKREAVQEERQRG------KDRNENEVESTSSANEDM----------PVE 233

Query: 300 RSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMIN 359
           R  +  LA+    +  V A +   P    S  DP     +A         AD++L  ++ 
Sbjct: 234 RILEAELAVEPKTETYVEANMGLNPS---SPNDPVTNICQA---------ADKQLFTLVE 281

Query: 360 WAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVE 419
           WAKR+P F +L L DQV LL   W E+L+     RS+     +L A  L + RN      
Sbjct: 282 WAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSA- 340

Query: 420 GMVEIFDMLLA-TSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRV 478
           G+  IFD +L    S+ R M +   E  CL++I+L N           K L     +  +
Sbjct: 341 GVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFN--------PDSKGLSNPAEVEAL 392

Query: 479 LDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYD 538
            +K+      L A       +Q  R A+LLL L  +R +  K +EHL+  K     P+  
Sbjct: 393 REKV---YASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDT 449

Query: 539 LLLEMLDA 546
            L+EML+A
Sbjct: 450 FLMEMLEA 457


>gi|158508572 nuclear receptor subfamily 3, group C, member 2 [Homo
           sapiens]
          Length = 984

 Score =  169 bits (428), Expect = 7e-42
 Identities = 109/375 (29%), Positives = 188/375 (50%), Gaps = 31/375 (8%)

Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
           S++   S++  S++ ++ C VC D ASG HYGV +C  CK FFKR+++G ++Y+C   N 
Sbjct: 585 SSSTLRSVSTGSSRPSKICLVCGDEASGCHYGVVTCGSCKVFFKRAVEGQHNYLCAGRND 644

Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQ-------------RDD 273
           C IDK RRK+C ACRL+KC + GM  G  +  + G     H+ Q             +  
Sbjct: 645 CIIDKIRRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPPPQSP 704

Query: 274 GEGRGEVGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDP 333
            EG   +  A +       PS       + ++++ +LT    V  L + EP I+Y+ YD 
Sbjct: 705 EEGTTYIAPAKE-------PSVNTALVPQLSTISRALTPSP-VMVLENIEPEIVYAGYDS 756

Query: 334 TRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVW 393
           ++P +  +++  L  LA ++++ ++ WAK +PGF +L L DQ+ L++ +W+ +    L W
Sbjct: 757 SKPDTAENLLSTLNRLAGKQMIQVVKWAKVLPGFKNLPLEDQITLIQYSWMCLSSFALSW 816

Query: 394 RSMEHPGK--LLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSI 451
           RS +H     L FAP+L+ +  +      M E+   +   S +F  + L  EE+  +K +
Sbjct: 817 RSYKHTNSQFLYFAPDLVFNEEK-MHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVL 875

Query: 452 ILLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLIL 511
           +LL++     L S     E + +  + L K       ++ K      Q  QR  QL  +L
Sbjct: 876 LLLSTIPKDGLKSQAAFEEMRTNYIKELRK-------MVTKCPNNSGQSWQRFYQLTKLL 928

Query: 512 SHIRHMSNKGMEHLY 526
             +  + +  +E  +
Sbjct: 929 DSMHDLVSDLLEFCF 943


>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
          Length = 463

 Score =  166 bits (421), Expect = 4e-41
 Identities = 115/365 (31%), Positives = 169/365 (46%), Gaps = 50/365 (13%)

Query: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
           CA+C D +SG HYGV+SCEGCK FFKR+I+    Y C     C IDK +R  CQ CR +K
Sbjct: 139 CAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQK 198

Query: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
           C  +GM +  ++++R        +R R+  E   E  ++G                    
Sbjct: 199 CLVMGMKREAVQEER--------QRSRERAESEAECATSGH------------------- 231

Query: 305 SLALSLTADQMVSALLDAE---PPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWA 361
                   D  V  +L+AE    P   S  D     S    +  + + AD++L  ++ WA
Sbjct: 232 -------EDMPVERILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWA 284

Query: 362 KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGM 421
           KR+P F DLTL DQV LL   W E+L+     RS+     +L A  L + R+      G+
Sbjct: 285 KRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSA-GV 343

Query: 422 VEIFDMLLA-TSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHRVLD 480
             IFD +L    S+ + M +   E  CL++I+L N           K L     +  + +
Sbjct: 344 GSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDA--------KGLSNPSEVETLRE 395

Query: 481 KITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL 540
           K+  T   L A       +Q  R A+LLL L  +R +  K +EHL+  K     P+   L
Sbjct: 396 KVYAT---LEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFL 452

Query: 541 LEMLD 545
           +EML+
Sbjct: 453 MEMLE 457


>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  165 bits (417), Expect = 1e-40
 Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)

Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
           S+    S    +    + C VC+D ASG HYGV +C  CK FFKR+++G ++Y+C   N 
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462

Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
           C IDK RRK+C ACR RKC + GM      + R+  + +K  +Q   G  +    + G+ 
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518

Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
                                L      +VS L   EP +LY+ YD + P S   +M  L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563

Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
             L  R+++  + WAK +PGF +L L DQ+ LL+ +W+ ++   L WRS        L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623

Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
           AP+L+++  Q   +  M +    +L  SS    + +  EE++C+K+++LL+S        
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678

Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
            LKS E       + D+I  T I  + KA +  +    Q  QR  QL  +L  +  +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728


>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  165 bits (417), Expect = 1e-40
 Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)

Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
           S+    S    +    + C VC+D ASG HYGV +C  CK FFKR+++G ++Y+C   N 
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462

Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
           C IDK RRK+C ACR RKC + GM      + R+  + +K  +Q   G  +    + G+ 
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518

Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
                                L      +VS L   EP +LY+ YD + P S   +M  L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563

Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
             L  R+++  + WAK +PGF +L L DQ+ LL+ +W+ ++   L WRS        L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623

Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
           AP+L+++  Q   +  M +    +L  SS    + +  EE++C+K+++LL+S        
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678

Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
            LKS E       + D+I  T I  + KA +  +    Q  QR  QL  +L  +  +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728


>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  165 bits (417), Expect = 1e-40
 Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)

Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
           S+    S    +    + C VC+D ASG HYGV +C  CK FFKR+++G ++Y+C   N 
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462

Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
           C IDK RRK+C ACR RKC + GM      + R+  + +K  +Q   G  +    + G+ 
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518

Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
                                L      +VS L   EP +LY+ YD + P S   +M  L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563

Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
             L  R+++  + WAK +PGF +L L DQ+ LL+ +W+ ++   L WRS        L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623

Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
           AP+L+++  Q   +  M +    +L  SS    + +  EE++C+K+++LL+S        
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678

Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
            LKS E       + D+I  T I  + KA +  +    Q  QR  QL  +L  +  +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728


>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  165 bits (417), Expect = 1e-40
 Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)

Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
           S+    S    +    + C VC+D ASG HYGV +C  CK FFKR+++G ++Y+C   N 
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462

Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
           C IDK RRK+C ACR RKC + GM      + R+  + +K  +Q   G  +    + G+ 
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518

Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
                                L      +VS L   EP +LY+ YD + P S   +M  L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563

Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
             L  R+++  + WAK +PGF +L L DQ+ LL+ +W+ ++   L WRS        L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623

Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
           AP+L+++  Q   +  M +    +L  SS    + +  EE++C+K+++LL+S        
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678

Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
            LKS E       + D+I  T I  + KA +  +    Q  QR  QL  +L  +  +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728


>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  165 bits (417), Expect = 1e-40
 Identities = 111/357 (31%), Positives = 173/357 (48%), Gaps = 37/357 (10%)

Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
           S+    S    +    + C VC+D ASG HYGV +C  CK FFKR+++G ++Y+C   N 
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462

Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
           C IDK RRK+C ACR RKC + GM      + R+  + +K  +Q   G  +    + G+ 
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518

Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
                                L      +VS L   EP +LY+ YD + P S   +M  L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563

Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
             L  R+++  + WAK +PGF +L L DQ+ LL+ +W+ ++   L WRS        L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623

Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
           AP+L+++  Q   +  M +    +L  SS    + +  EE++C+K+++LL+S        
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678

Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
            LKS E       + D+I  T I  + KA +  +    Q  QR  QL  +L  +  +
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 728


>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
           beta [Homo sapiens]
          Length = 742

 Score =  164 bits (416), Expect = 2e-40
 Identities = 111/351 (31%), Positives = 171/351 (48%), Gaps = 37/351 (10%)

Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQ 226
           S+    S    +    + C VC+D ASG HYGV +C  CK FFKR+++G ++Y+C   N 
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRND 462

Query: 227 CTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDM 286
           C IDK RRK+C ACR RKC + GM      + R+  + +K  +Q   G  +    + G+ 
Sbjct: 463 CIIDKIRRKNCPACRYRKCLQAGMN----LEARKTKKKIKGIQQATTGVSQETSENPGNK 518

Query: 287 RAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLL 346
                                L      +VS L   EP +LY+ YD + P S   +M  L
Sbjct: 519 TIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTL 563

Query: 347 TNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLF 404
             L  R+++  + WAK +PGF +L L DQ+ LL+ +W+ ++   L WRS        L F
Sbjct: 564 NMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCF 623

Query: 405 APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSS 464
           AP+L+++  Q   +  M +    +L  SS    + +  EE++C+K+++LL+S        
Sbjct: 624 APDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPKD 678

Query: 465 TLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLIL 511
            LKS E       + D+I  T I  + KA +  +    Q  QR  QL  +L
Sbjct: 679 GLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLL 722


>gi|21322252 androgen receptor isoform 1 [Homo sapiens]
          Length = 920

 Score =  162 bits (411), Expect = 6e-40
 Identities = 128/465 (27%), Positives = 209/465 (44%), Gaps = 64/465 (13%)

Query: 67  AANAQVYGQTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHPPPQL----SPFLQ 122
           A   Q+YG  G   G G      G  G GG     + + +P     PP  L    S F  
Sbjct: 441 AEEGQLYGPCGGGGGGGGGGGGGGGGGGGGGGG-EAGAVAPYGYTRPPQGLAGQESDFTA 499

Query: 123 PHG-------QQVPYYLENEPSGYTVR-EAGP--PAFYRPNSDNRRQGGRERLASTNDKG 172
           P          +VPY     PS   V+ E GP   ++  P  D R +  R+ +   +   
Sbjct: 500 PDVWYPGGMVSRVPY-----PSPTCVKSEMGPWMDSYSGPYGDMRLETARDHVLPID--- 551

Query: 173 SMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKN 232
                     + C +C D ASG HYG  +C  CK FFKR+ +G   Y+C + N CTIDK 
Sbjct: 552 ----YYFPPQKTCLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKF 607

Query: 233 RRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLW 292
           RRK+C +CRLRKCYE GM  G  +  + G   L+ +         GE  S          
Sbjct: 608 RRKNCPSCRLRKCYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS------- 651

Query: 293 PSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR 352
           P+    ++   + +         ++ L   EP ++ + +D  +P S A+++  L  L +R
Sbjct: 652 PTEETTQKLTVSHIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGER 711

Query: 353 ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLL 410
           +LVH++ WAK +PGF +L + DQ+ +++ +W+ +++  + WRS  +     L FAP+L+ 
Sbjct: 712 QLVHVVKWAKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF 771

Query: 411 D-------RNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLS 463
           +       R   +CV         +   S  F  + +  +EF+C+K+++L +        
Sbjct: 772 NEYRMHKSRMYSQCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPV 819

Query: 464 STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
             LK+ +  D +     K  D +I    K   +  ++  +L +LL
Sbjct: 820 DGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 864


>gi|27894344 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score =  162 bits (411), Expect = 6e-40
 Identities = 151/539 (28%), Positives = 230/539 (42%), Gaps = 109/539 (20%)

Query: 55  PEGAAYEFNAAAAANAQVYG-QTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHP 113
           P  A+++F      + QVYG   G   GP  EA +   +   G P     +PSP      
Sbjct: 96  PASASFKFE-----DFQVYGCYPGPLSGPVDEALSSSGSDYYGSP---CSAPSPSTPSFQ 147

Query: 114 PPQLSPF---------------LQPHGQQVP----------YYLENEPSGYTVREAGPPA 148
           PPQLSP+               L+   +Q+P          ++  + P+G +   A  P 
Sbjct: 148 PPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPL 207

Query: 149 FYRPNSDNRRQGGRERLAS------------------------TNDKGSMAMESAKETRY 184
              P+    + G  E  +                         T+ K         E R 
Sbjct: 208 KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGR- 266

Query: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
           CAVC D AS  HYGV +CEGCK FFKR++Q +  Y+C A   C +DK RR  CQ CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326

Query: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
           C  VGM+K  +R D   GR             RG +              P   K+    
Sbjct: 327 CLAVGMVKEVVRTDSLKGR-------------RGRL--------------PSKPKQPPDA 359

Query: 305 SLALSLTADQMVSALLDAEPPILYSEYD-------PTRPFSEASMMGLLTNLADRELVHM 357
           S A  LT+  +V A LD+ P     +Y        P     +A  +    +L    L  +
Sbjct: 360 SPANLLTS--LVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVI 417

Query: 358 INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKC 417
             WA+++PGF +L+  DQ  LLE A+LE+ ++ L +RS    GKL+F   L+L R Q  C
Sbjct: 418 RKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--C 475

Query: 418 VEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHR 477
             G  +  D +LA S     + +    F CL +++L+         +    L+E   +  
Sbjct: 476 ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI---------TDRHGLQEPRRVEE 526

Query: 478 VLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVP 535
           + ++I   L  H+ A AG    Q    L++LL  L  +R +  +G++ ++ +K +++VP
Sbjct: 527 LQNRIASCLKEHVAAVAG--EPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583


>gi|21361342 nuclear receptor subfamily 4, group A, member 1 [Homo
           sapiens]
          Length = 598

 Score =  162 bits (411), Expect = 6e-40
 Identities = 151/539 (28%), Positives = 230/539 (42%), Gaps = 109/539 (20%)

Query: 55  PEGAAYEFNAAAAANAQVYG-QTGLPYGPGSEAAAFGSNGLGGFPPLNSVSPSPLMLLHP 113
           P  A+++F      + QVYG   G   GP  EA +   +   G P     +PSP      
Sbjct: 96  PASASFKFE-----DFQVYGCYPGPLSGPVDEALSSSGSDYYGSP---CSAPSPSTPSFQ 147

Query: 114 PPQLSPF---------------LQPHGQQVP----------YYLENEPSGYTVREAGPPA 148
           PPQLSP+               L+   +Q+P          ++  + P+G +   A  P 
Sbjct: 148 PPQLSPWDGSFGHFSPSQTYEGLRAWTEQLPKASGPPQPPAFFSFSPPTGPSPSLAQSPL 207

Query: 149 FYRPNSDNRRQGGRERLAS------------------------TNDKGSMAMESAKETRY 184
              P+    + G  E  +                         T+ K         E R 
Sbjct: 208 KLFPSQATHQLGEGESYSMPTAFPGLAPTSPHLEGSGILDTPVTSTKARSGAPGGSEGR- 266

Query: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
           CAVC D AS  HYGV +CEGCK FFKR++Q +  Y+C A   C +DK RR  CQ CR +K
Sbjct: 267 CAVCGDNASCQHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQK 326

Query: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
           C  VGM+K  +R D   GR             RG +              P   K+    
Sbjct: 327 CLAVGMVKEVVRTDSLKGR-------------RGRL--------------PSKPKQPPDA 359

Query: 305 SLALSLTADQMVSALLDAEPPILYSEYD-------PTRPFSEASMMGLLTNLADRELVHM 357
           S A  LT+  +V A LD+ P     +Y        P     +A  +    +L    L  +
Sbjct: 360 SPANLLTS--LVRAHLDSGPSTAKLDYSKFQELVLPHFGKEDAGDVQQFYDLLSGSLEVI 417

Query: 358 INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKC 417
             WA+++PGF +L+  DQ  LLE A+LE+ ++ L +RS    GKL+F   L+L R Q  C
Sbjct: 418 RKWAEKIPGFAELSPADQDLLLESAFLELFILRLAYRSKPGEGKLIFCSGLVLHRLQ--C 475

Query: 418 VEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHIHR 477
             G  +  D +LA S     + +    F CL +++L+         +    L+E   +  
Sbjct: 476 ARGFGDWIDSILAFSRSLHSLLVDVPAFACLSALVLI---------TDRHGLQEPRRVEE 526

Query: 478 VLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVP 535
           + ++I   L  H+ A AG    Q    L++LL  L  +R +  +G++ ++ +K +++VP
Sbjct: 527 LQNRIASCLKEHVAAVAG--EPQPASCLSRLLGKLPELRTLCTQGLQRIFYLKLEDLVP 583


>gi|66528677 nuclear receptor subfamily 3, group C, member 1 isoform
           gamma [Homo sapiens]
          Length = 778

 Score =  160 bits (405), Expect = 3e-39
 Identities = 111/358 (31%), Positives = 173/358 (48%), Gaps = 38/358 (10%)

Query: 167 STNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGH-NDYMCPATN 225
           S+    S    +    + C VC+D ASG HYGV +C  CK FFKR+++G  ++Y+C   N
Sbjct: 403 SSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGRQHNYLCAGRN 462

Query: 226 QCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGD 285
            C IDK RRK+C ACR RKC + GM      + R+  + +K  +Q   G  +    + G+
Sbjct: 463 DCIIDKIRRKNCPACRYRKCLQAGMNL----EARKTKKKIKGIQQATTGVSQETSENPGN 518

Query: 286 MRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGL 345
                                 L      +VS L   EP +LY+ YD + P S   +M  
Sbjct: 519 KTIV---------------PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTT 563

Query: 346 LTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LL 403
           L  L  R+++  + WAK +PGF +L L DQ+ LL+ +W+ ++   L WRS        L 
Sbjct: 564 LNMLGGRQVIAAVKWAKAIPGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLC 623

Query: 404 FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLS 463
           FAP+L+++  Q   +  M +    +L  SS    + +  EE++C+K+++LL+S       
Sbjct: 624 FAPDLIIN-EQRMTLPCMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS----VPK 678

Query: 464 STLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQ----QQHQRLAQLLLILSHIRHM 517
             LKS E       + D+I  T I  + KA +  +    Q  QR  QL  +L  +  +
Sbjct: 679 DGLKSQE-------LFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEV 729


>gi|58535455 androgen receptor isoform 2 [Homo sapiens]
          Length = 388

 Score =  158 bits (400), Expect = 1e-38
 Identities = 97/333 (29%), Positives = 165/333 (49%), Gaps = 37/333 (11%)

Query: 185 CAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRKSCQACRLRK 244
           C +C D ASG HYG  +C  CK FFKR+ +G   Y+C + N CTIDK RRK+C +CRLRK
Sbjct: 28  CLICGDEASGCHYGALTCGSCKVFFKRAAEGKQKYLCASRNDCTIDKFRRKNCPSCRLRK 87

Query: 245 CYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPSPLMIKRSKKN 304
           CYE GM  G  +  + G   L+ +         GE  S          P+    ++   +
Sbjct: 88  CYEAGMTLGARKLKKLGNLKLQEE---------GEASSTTS-------PTEETTQKLTVS 131

Query: 305 SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRV 364
            +         ++ L   EP ++ + +D  +P S A+++  L  L +R+LVH++ WAK +
Sbjct: 132 HIEGYECQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAKAL 191

Query: 365 PGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGK--LLFAPNLLLD-------RNQG 415
           PGF +L + DQ+ +++ +W+ +++  + WRS  +     L FAP+L+ +       R   
Sbjct: 192 PGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVFNEYRMHKSRMYS 251

Query: 416 KCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDHI 475
           +CV         +   S  F  + +  +EF+C+K+++L +          LK+ +  D +
Sbjct: 252 QCVR--------MRHLSQEFGWLQITPQEFLCMKALLLFS----IIPVDGLKNQKFFDEL 299

Query: 476 HRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLL 508
                K  D +I    K   +  ++  +L +LL
Sbjct: 300 RMNYIKELDRIIACKRKNPTSCSRRFYQLTKLL 332


>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
           sapiens]
          Length = 598

 Score =  155 bits (393), Expect = 8e-38
 Identities = 114/384 (29%), Positives = 181/384 (47%), Gaps = 46/384 (11%)

Query: 160 GGRERLASTNDKGSMAMESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDY 219
           G   +L  T      +  S      CAVC D A+  HYGV +CEGCK FFKR++Q +  Y
Sbjct: 238 GHASQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKY 297

Query: 220 MCPATNQCTIDKNRRKSCQACRLRKCYEVGMMKGGIRKDRRGGRMLKHKRQRDDGEGRGE 279
           +C A   C +DK RR  CQ CR +KC  VGM+K  +R D   GR             RG 
Sbjct: 298 VCLANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGR-------------RGR 344

Query: 280 VGSAGDMRAANLWPSPLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSE 339
           + S          PSP            +SL +  +V A +D+ P +   +Y   +   +
Sbjct: 345 LPSKPKSPQEPSPPSP-----------PVSLIS-ALVRAHVDSNPAMTSLDYSRFQANPD 392

Query: 340 ASMMGLLT-------NLADRELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLV 392
             M G  T       +L    +  +  WA+++PGF DL   DQ  L E A+LE+ ++ L 
Sbjct: 393 YQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLA 452

Query: 393 WRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII 452
           +RS    GKL+F   ++L R Q  CV G  E  D ++  SS  + MN+    F C+ ++ 
Sbjct: 453 YRSNPVEGKLIFCNGVVLHRLQ--CVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALA 510

Query: 453 LLNSGVYTFLSSTLKSLEEKDHIHRVLDKITDTL-IHLMAKAGLTLQQQHQRLAQLLLIL 511
           ++         +    L+E   +  + +KI + L  H+    G   +  +  L++LL  L
Sbjct: 511 MV---------TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNY--LSKLLGKL 559

Query: 512 SHIRHMSNKGMEHLYSMKCKNVVP 535
             +R +  +G++ ++ +K +++VP
Sbjct: 560 PELRTLCTQGLQRIFYLKLEDLVP 583


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,780,357
Number of Sequences: 37866
Number of extensions: 1250506
Number of successful extensions: 4268
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 61
Number of HSP's that attempted gapping in prelim test: 3916
Number of HSP's gapped (non-prelim): 291
length of query: 595
length of database: 18,247,518
effective HSP length: 108
effective length of query: 487
effective length of database: 14,157,990
effective search space: 6894941130
effective search space used: 6894941130
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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