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Search of human proteins with 169881252
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169881252 general transcription factor II, i isoform 4 [Homo
sapiens]
(957 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169881252 general transcription factor II, i isoform 4 [Homo ... 1914 0.0
gi|14670354 general transcription factor II, i isoform 3 [Homo s... 1902 0.0
gi|14670352 general transcription factor II, i isoform 2 [Homo s... 1902 0.0
gi|14670350 general transcription factor II, i isoform 1 [Homo s... 1890 0.0
gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens] 453 e-127
gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens] 453 e-127
gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo sapi... 385 e-106
gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo sap... 379 e-105
gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo ... 159 2e-38
gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens] 131 3e-30
gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens] 131 3e-30
gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens] 131 3e-30
gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo sap... 129 1e-29
gi|239752592 PREDICTED: hypothetical protein XP_002348308, parti... 129 2e-29
gi|239740995 PREDICTED: hypothetical protein XP_002342058 [Homo ... 113 7e-25
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 46 2e-04
gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens] 37 0.12
gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens] 37 0.12
gi|110349719 titin isoform N2-A [Homo sapiens] 36 0.15
gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens] 36 0.15
gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform ... 36 0.20
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 34 0.57
gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens] 34 0.75
gi|239757124 PREDICTED: hypothetical protein [Homo sapiens] 33 0.98
gi|113428448 PREDICTED: hypothetical protein [Homo sapiens] 33 0.98
gi|169213522 PREDICTED: hypothetical protein [Homo sapiens] 33 0.98
gi|226491199 coiled-coil domain containing 38 [Homo sapiens] 32 2.2
gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens] 32 2.2
gi|146134388 YLP motif containing 1 [Homo sapiens] 32 2.2
gi|91199550 CD68 antigen isoform B [Homo sapiens] 32 2.8
>gi|169881252 general transcription factor II, i isoform 4 [Homo
sapiens]
Length = 957
Score = 1914 bits (4958), Expect = 0.0
Identities = 957/957 (100%), Positives = 957/957 (100%)
Query: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
Query: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
Query: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANA 300
EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANA
Sbjct: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANA 300
Query: 301 GKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEG 360
GKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEG
Sbjct: 301 GKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEG 360
Query: 361 LPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYA 420
LPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYA
Sbjct: 361 LPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYA 420
Query: 421 RITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGI 480
RITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGI
Sbjct: 421 RITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGI 480
Query: 481 PRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 540
PRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL
Sbjct: 481 PRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 540
Query: 541 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 600
KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF
Sbjct: 541 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 600
Query: 601 VVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAV 660
VVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAV
Sbjct: 601 VVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAV 660
Query: 661 RTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFAL 720
RTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFAL
Sbjct: 661 RTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFAL 720
Query: 721 FESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSS 780
FESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSS
Sbjct: 721 FESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSS 780
Query: 781 KSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFG 840
KSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFG
Sbjct: 781 KSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFG 840
Query: 841 EAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI 900
EAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI
Sbjct: 841 EAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI 900
Query: 901 RPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 957
RPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW
Sbjct: 901 RPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 957
>gi|14670354 general transcription factor II, i isoform 3 [Homo
sapiens]
Length = 977
Score = 1902 bits (4927), Expect = 0.0
Identities = 957/977 (97%), Positives = 957/977 (97%), Gaps = 20/977 (2%)
Query: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
Query: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
Query: 241 EESEDPDYYQYNIQ--------------------GSHHSSEGNEGTEMEVPAEDDDYSPP 280
EESEDPDYYQYNIQ GSHHSSEGNEGTEMEVPAEDDDYSPP
Sbjct: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDDDYSPP 300
Query: 281 SKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKG 340
SKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKG
Sbjct: 301 SKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKG 360
Query: 341 PVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNS 400
PVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNS
Sbjct: 361 PVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNS 420
Query: 401 TREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPND 460
TREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPND
Sbjct: 421 TREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPND 480
Query: 461 LYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVK 520
LYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVK
Sbjct: 481 LYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVK 540
Query: 521 EDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSP 580
EDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSP
Sbjct: 541 EDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSP 600
Query: 581 TWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKV 640
TWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKV
Sbjct: 601 TWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKV 660
Query: 641 PEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLF 700
PEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLF
Sbjct: 661 PEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLF 720
Query: 701 NEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKI 760
NEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKI
Sbjct: 721 NEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKI 780
Query: 761 KFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSK 820
KFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSK
Sbjct: 781 KFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSK 840
Query: 821 VEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYL 880
VEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYL
Sbjct: 841 VEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYL 900
Query: 881 EISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEI 940
EISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEI
Sbjct: 901 EISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEEI 960
Query: 941 KETDGSSQIKQEPDPTW 957
KETDGSSQIKQEPDPTW
Sbjct: 961 KETDGSSQIKQEPDPTW 977
>gi|14670352 general transcription factor II, i isoform 2 [Homo
sapiens]
Length = 978
Score = 1902 bits (4926), Expect = 0.0
Identities = 957/978 (97%), Positives = 957/978 (97%), Gaps = 21/978 (2%)
Query: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
Query: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
Query: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAED---------------------DDYSP 279
EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAED DDYSP
Sbjct: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPSETSEDPEVEVTIEDDDYSP 300
Query: 280 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 339
PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK
Sbjct: 301 PSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAK 360
Query: 340 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 399
GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN
Sbjct: 361 GPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLN 420
Query: 400 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 459
STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN
Sbjct: 421 STREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPN 480
Query: 460 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 519
DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV
Sbjct: 481 DLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPV 540
Query: 520 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 579
KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS
Sbjct: 541 KEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRS 600
Query: 580 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 639
PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK
Sbjct: 601 PTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK 660
Query: 640 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 699
VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL
Sbjct: 661 VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENL 720
Query: 700 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 759
FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK
Sbjct: 721 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 780
Query: 760 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 819
IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS
Sbjct: 781 IKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLS 840
Query: 820 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 879
KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY
Sbjct: 841 KVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSY 900
Query: 880 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 939
LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE
Sbjct: 901 LEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESEGPVIQESAEPSQLEVPATEE 960
Query: 940 IKETDGSSQIKQEPDPTW 957
IKETDGSSQIKQEPDPTW
Sbjct: 961 IKETDGSSQIKQEPDPTW 978
>gi|14670350 general transcription factor II, i isoform 1 [Homo
sapiens]
Length = 998
Score = 1890 bits (4895), Expect = 0.0
Identities = 957/998 (95%), Positives = 957/998 (95%), Gaps = 41/998 (4%)
Query: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
Query: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF
Sbjct: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
Query: 241 EESEDPDYYQYNIQ--------------------GSHHSSEGNEGTEMEVPAED------ 274
EESEDPDYYQYNIQ GSHHSSEGNEGTEMEVPAED
Sbjct: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300
Query: 275 ---------------DDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 319
DDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD
Sbjct: 301 SETSEDPEVEVTIEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 360
Query: 320 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 379
LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE
Sbjct: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420
Query: 380 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 439
RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE
Sbjct: 421 RILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAE 480
Query: 440 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 499
ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR
Sbjct: 481 ALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKR 540
Query: 500 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 559
PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF
Sbjct: 541 PELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYPVF 600
Query: 560 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 619
ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK
Sbjct: 601 ESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASK 660
Query: 620 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 679
INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE
Sbjct: 661 INTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGRE 720
Query: 680 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 739
FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF
Sbjct: 721 FSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPF 780
Query: 740 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 799
RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG
Sbjct: 781 RRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTASG 840
Query: 800 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 859
VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN
Sbjct: 841 VEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYRKITIN 900
Query: 860 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 919
PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE
Sbjct: 901 PGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVINNQLVDQSESE 960
Query: 920 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 957
GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW
Sbjct: 961 GPVIQESAEPSQLEVPATEEIKETDGSSQIKQEPDPTW 998
>gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
Length = 949
Score = 453 bits (1166), Expect = e-127
Identities = 252/441 (57%), Positives = 300/441 (68%), Gaps = 32/441 (7%)
Query: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1 MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
Query: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
RG AFVN R DFQKDF KYCV E + ++K N M V + E E LRK VEDYF
Sbjct: 61 RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115
Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175
Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
SFII RPFL P+ +GG MVTDA+RSI+SP SCGPI VKTEP EDSGISL+ AV+VK
Sbjct: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235
Query: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANA 300
+ESEDP+YYQYN+QGSH SS NE EME+P ED PS+ P NE P+ V N
Sbjct: 236 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEP--NEDPEAEVKIEGNT 293
Query: 301 GKRK-------VREFNFEKWNA------------RITDLRKQVEELFERKYAQAIKAKGP 341
V + N + +I LR+QV +LF RK+ +AI P
Sbjct: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353
Query: 342 VTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKH----EL 397
V +PY + + ++G+P G+ F+ P I + RIL A E I+F + + EL
Sbjct: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413
Query: 398 LNSTREDLQLDKPASGVKEEW 418
N + ++D+ +E+W
Sbjct: 414 SNVGKR--KIDQEGRVFQEKW 432
Score = 205 bits (521), Expect = 2e-52
Identities = 100/140 (71%), Positives = 118/140 (84%)
Query: 789 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 848
+S +V +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353
Query: 849 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 908
VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413
Query: 909 NNQLVDQSESEGPVIQESAE 928
+N + + EG V QE E
Sbjct: 414 SNVGKRKIDQEGRVFQEKWE 433
Score = 90.1 bits (222), Expect = 9e-18
Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)
Query: 320 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 379
LRK VE+ F Y +A+ V +PY + V+GLPEG+ F+ P Y + L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
Query: 380 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 434
IL K I F+I + L L ++ E K M D
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
Query: 435 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 481
K AEA+ + P Y +HP+ +L +E +P P+ P
Sbjct: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283
Query: 482 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 540
E I+ V + + +VT P N + +I +LR+QV ++F+
Sbjct: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342
Query: 541 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 600
KF +A+G+ VKVPY NP + ++G+P G+ F++P + I + RI+ + IKF
Sbjct: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402
Query: 601 VVKKP 605
V +P
Sbjct: 403 TVIRP 407
Score = 85.5 bits (210), Expect = 2e-16
Identities = 80/308 (25%), Positives = 127/308 (41%), Gaps = 77/308 (25%)
Query: 530 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 589
LRK VE+ F + +ALG T V VPY + + V+GLPEG+ F+ P + + L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
Query: 590 RIVRGSNKIKFVVKKPEL------------------VISYLPPGMASKINTK-------- 623
I+ I F++ +P L ++S P IN K
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVS--PSESCGPINVKTEPMEDSG 224
Query: 624 ------ALQSPKRPRSP-------------GSNSKVPEIEVTVEGPN--------NNNPQ 656
A+ K P ++++V E+E+ +E N +P+
Sbjct: 225 ISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPE 284
Query: 657 TSAVRTPTQTNGSN-----------------VPFKPRGREFSFEAWNAKITDLKQKVENL 699
+ V+ TN S+ VP + R S E KI L+++V +L
Sbjct: 285 -AEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVNDL 339
Query: 700 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 759
F+ K GEA+G+ VKVP+ P ++G+P GV F+ P I + +IL
Sbjct: 340 FSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEF 399
Query: 760 IKFIIKKP 767
IKF + +P
Sbjct: 400 IKFTVIRP 407
Score = 65.9 bits (159), Expect = 2e-10
Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)
Query: 827 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 886
LR+ V D F +G+A+G V VPY K+ + VVV G+P GV+F+ P ++++++
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
Query: 887 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 933
IL++ I F + RPF PG+V + +V SES GP V E E S +
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
Query: 934 VPATEEIKETDGSSQIKQEPDPTW 957
+ A + S K+ DP +
Sbjct: 227 LKA-------EAVSVKKESEDPNY 243
>gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]
Length = 949
Score = 453 bits (1166), Expect = e-127
Identities = 252/441 (57%), Positives = 300/441 (68%), Gaps = 32/441 (7%)
Query: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1 MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
Query: 61 RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120
RG AFVN R DFQKDF KYCV E + ++K N M V + E E LRK VEDYF
Sbjct: 61 RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115
Query: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180
CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175
Query: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240
SFII RPFL P+ +GG MVTDA+RSI+SP SCGPI VKTEP EDSGISL+ AV+VK
Sbjct: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235
Query: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANA 300
+ESEDP+YYQYN+QGSH SS NE EME+P ED PS+ P NE P+ V N
Sbjct: 236 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEP--NEDPEAEVKIEGNT 293
Query: 301 GKRK-------VREFNFEKWNA------------RITDLRKQVEELFERKYAQAIKAKGP 341
V + N + +I LR+QV +LF RK+ +AI P
Sbjct: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353
Query: 342 VTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKH----EL 397
V +PY + + ++G+P G+ F+ P I + RIL A E I+F + + EL
Sbjct: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413
Query: 398 LNSTREDLQLDKPASGVKEEW 418
N + ++D+ +E+W
Sbjct: 414 SNVGKR--KIDQEGRVFQEKW 432
Score = 205 bits (521), Expect = 2e-52
Identities = 100/140 (71%), Positives = 118/140 (84%)
Query: 789 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 848
+S +V +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353
Query: 849 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 908
VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413
Query: 909 NNQLVDQSESEGPVIQESAE 928
+N + + EG V QE E
Sbjct: 414 SNVGKRKIDQEGRVFQEKWE 433
Score = 90.1 bits (222), Expect = 9e-18
Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)
Query: 320 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 379
LRK VE+ F Y +A+ V +PY + V+GLPEG+ F+ P Y + L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
Query: 380 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 434
IL K I F+I + L L ++ E K M D
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
Query: 435 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 481
K AEA+ + P Y +HP+ +L +E +P P+ P
Sbjct: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283
Query: 482 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 540
E I+ V + + +VT P N + +I +LR+QV ++F+
Sbjct: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342
Query: 541 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 600
KF +A+G+ VKVPY NP + ++G+P G+ F++P + I + RI+ + IKF
Sbjct: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402
Query: 601 VVKKP 605
V +P
Sbjct: 403 TVIRP 407
Score = 85.5 bits (210), Expect = 2e-16
Identities = 80/308 (25%), Positives = 127/308 (41%), Gaps = 77/308 (25%)
Query: 530 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 589
LRK VE+ F + +ALG T V VPY + + V+GLPEG+ F+ P + + L+
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
Query: 590 RIVRGSNKIKFVVKKPEL------------------VISYLPPGMASKINTK-------- 623
I+ I F++ +P L ++S P IN K
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVS--PSESCGPINVKTEPMEDSG 224
Query: 624 ------ALQSPKRPRSP-------------GSNSKVPEIEVTVEGPN--------NNNPQ 656
A+ K P ++++V E+E+ +E N +P+
Sbjct: 225 ISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPE 284
Query: 657 TSAVRTPTQTNGSN-----------------VPFKPRGREFSFEAWNAKITDLKQKVENL 699
+ V+ TN S+ VP + R S E KI L+++V +L
Sbjct: 285 -AEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVNDL 339
Query: 700 FNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAK 759
F+ K GEA+G+ VKVP+ P ++G+P GV F+ P I + +IL
Sbjct: 340 FSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEF 399
Query: 760 IKFIIKKP 767
IKF + +P
Sbjct: 400 IKFTVIRP 407
Score = 65.9 bits (159), Expect = 2e-10
Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)
Query: 827 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 886
LR+ V D F +G+A+G V VPY K+ + VVV G+P GV+F+ P ++++++
Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
Query: 887 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 933
IL++ I F + RPF PG+V + +V SES GP V E E S +
Sbjct: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
Query: 934 VPATEEIKETDGSSQIKQEPDPTW 957
+ A + S K+ DP +
Sbjct: 227 LKA-------EAVSVKKESEDPNY 243
>gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo
sapiens]
Length = 959
Score = 385 bits (988), Expect = e-106
Identities = 302/971 (31%), Positives = 464/971 (47%), Gaps = 173/971 (17%)
Query: 22 VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
++T L+SAL+SMC L+K AEVAC+AV++ FVVGTE+GR F+N RK+ Q DF+++C
Sbjct: 30 IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89
Query: 82 EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
K E K + R S++ ++ LRK VE+ F Y +ALG+++V
Sbjct: 90 GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149
Query: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
VP+PYE++LR+ + VQGLPEG+AF+ P YD L ILE+ I F +KRP +
Sbjct: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206
Query: 194 HVGGR--VMVTDADRSILSPGGS--CG----PIKVKTEPTEDSGISLEMAAVTVKEESED 245
GGR + + + L P GS CG KV + + S MA+
Sbjct: 207 --GGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMAS--------- 255
Query: 246 PDYYQYNIQGSHHSSE--GNEGTEMEVPAEDDDYSPPSKRPKANEL-------------P 290
+ Y+ +H+ E + D S P PKA P
Sbjct: 256 ---FLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGP 312
Query: 291 QPPVPEPANAGKR---KVREFNFEKWNARITD------LRKQVEELFERKYAQAIKAKGP 341
P+ + +A KR + EKW+A I + LR+ V+ LF +YA+A+
Sbjct: 313 GGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHM 372
Query: 342 VTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKK--HELL- 398
V +PY E + + G+P+ IPF+RP TYG+P+L+RIL + I F+IK+ E +
Sbjct: 373 VPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIF 432
Query: 399 --NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLFCK-KFAEALG-STEAKAVPYQ 452
N +D +PAS ++ +R T L + K +E G T + +
Sbjct: 433 TGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLR 492
Query: 453 KFEAHPNDLYV------------EGLPENIPFRSP---SWYGIPRLEKIIQVGNRIKFVI 497
+ P DL + E + +++P P S YG+
Sbjct: 493 PIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGM----------------- 535
Query: 498 KRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYP 557
E+LT PV++ I LRKQVE +FN ++A+A+G++E VKVPY
Sbjct: 536 ---EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYS 592
Query: 558 VFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYL-PPGM 616
F +PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+PEL+ + P M
Sbjct: 593 KFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIM 652
Query: 617 ASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPR 676
S+ +L P +S P ++ ++ K +
Sbjct: 653 DSQGTASSLGFSPPALPPERDSGDPLVDESL--------------------------KRQ 686
Query: 677 GREFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGL 733
G + +++A ++I L+++V++LFN+K GEALG+K V+VP+ +S P +EGL
Sbjct: 687 GFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGL 746
Query: 734 PEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNV 793
P G+PFR+P TFG LE+IL KIKF + +P
Sbjct: 747 PPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP-------------------------- 780
Query: 794 NTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPY 853
Q IP D + +++ + LREQV +LF+ K+GEA+G+ PV VPY
Sbjct: 781 ------------FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPY 828
Query: 854 RKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI---RPFPGLVINN 910
+ I +P V V G+P + F+ P+ +I + +IL + E ++ +I +PF + N+
Sbjct: 829 KLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPF-AEICND 887
Query: 911 QLVDQSESEGP 921
V +S P
Sbjct: 888 AKVPAKDSSIP 898
Score = 268 bits (684), Expect = 2e-71
Identities = 207/621 (33%), Positives = 291/621 (46%), Gaps = 107/621 (17%)
Query: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
+I TLR+ V+ F Y +ALG +VPVPY K+ D AV + G+P+ + FK P Y +
Sbjct: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406
Query: 168 ATLKWILENKAGISFIIKRPF----------------LEPKKHVG------GRVMVTDAD 205
LK ILE + I FIIKR F LEP R V D
Sbjct: 407 PKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLA 466
Query: 206 RSILSPGGS----CGPIKVKTEPTEDSGISLEMAAVT-VKEESEDPDYYQYNIQG-SHHS 259
+ S GS CGP G S E+ + +K E ED D Q + S S
Sbjct: 467 GNARSDKGSMSEDCGP-----------GTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTS 515
Query: 260 SEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 319
E + +P+ED Y K + E A +R V + + + I
Sbjct: 516 EEMTDSMPGHLPSEDSGYGMEMLTDKG-------LSEDARPEERPVEDSHGDV----IRP 564
Query: 320 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 379
LRKQVE LF +YA+AI PV +PY F H E+L+V GLPEGI RRP+ +GI +L
Sbjct: 565 LRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLR 624
Query: 380 RILLAKERIRFVIKKHELL-----------NSTREDLQLDKPA----------------- 411
+IL A I+FVIK+ ELL T L PA
Sbjct: 625 KILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESLK 684
Query: 412 -SGVKEEWYARITK------LRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVE 464
G +E + AR+++ LR+ V LF KK+ EALG VPY++ +++P + +E
Sbjct: 685 RQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIE 744
Query: 465 GLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWN 524
GLP IPFR P +G LE+I+ V ++IKF + RP Q P ++D N
Sbjct: 745 GLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRP----------FQGLIPKPDEDDAN 794
Query: 525 VRITK--LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTW 582
K LR+QV+E+FN K+ +ALGL V VPY + +P+ + V GLP+ IPFR+P
Sbjct: 795 RLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNT 854
Query: 583 FGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMA----SKINTKALQSPKRPRSPGSNS 638
+ I RLE+I++ ++ V +I+ L P +K+ K PKR R S
Sbjct: 855 YDIHRLEKILKAREHVRMV------IINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEG 908
Query: 639 KVPEIEVTVEGPNNNNPQTSA 659
+ +++NP + A
Sbjct: 909 NSVSSSSSSSSSSSSNPDSVA 929
Score = 143 bits (360), Expect = 9e-34
Identities = 118/426 (27%), Positives = 192/426 (45%), Gaps = 120/426 (28%)
Query: 422 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 481
I LRK V+ LF ++A+A+G +E VPY KF HP +L+V GLPE I R P+ +GI
Sbjct: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621
Query: 482 RLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTP----------------------- 518
+L KI++ N I+FVIKRPELLT E T
Sbjct: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDE 681
Query: 519 ------VKEDWNVRITK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFL 566
+E+++ R+++ LR+QV+++FN K+ EA+ + Y
Sbjct: 682 SLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYG------EALGIKY---------- 725
Query: 567 YVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQ 626
P +P++ RI + +I LPPG+ +
Sbjct: 726 -----PVQVPYK-----------RIKSNPGSV---------IIEGLPPGIPFR------- 753
Query: 627 SPKRPRSPGSNSK------VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 680
+P + GS + +I+ TV P + P + + + + K
Sbjct: 754 ---KPCTFGSQNLERILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK------ 799
Query: 681 SFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFR 740
L+++V+ LFNEK GEALGL + V VP+ L P+ V GLP+ +PFR
Sbjct: 800 ---------VILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFR 850
Query: 741 RPSTFGIPRLEKILRNKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPN 792
P+T+ I RLEKIL+ + ++ II + + F + K+S+ K ++++ +
Sbjct: 851 NPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNS 910
Query: 793 VNTTAS 798
V++++S
Sbjct: 911 VSSSSS 916
Score = 102 bits (255), Expect = 1e-21
Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)
Query: 530 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 589
LRK VEE+F++ +++ALG V +PY P L V+GLPEG+ FR P + L
Sbjct: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187
Query: 590 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 649
I+ S++I+F +K+P L ++N +L PK R G + + P++
Sbjct: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239
Query: 650 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 709
P + P PT T+ S F +S N I +LKQ+ + LG
Sbjct: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285
Query: 710 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 768
L + + P A + +DF ++P+ G P ++ + +K + I+ K E
Sbjct: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336
Query: 769 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 828
++ IKE+ ED+N LR
Sbjct: 337 KWDAFIKET-----------------------EDINT---------------------LR 352
Query: 829 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 888
E V LF+ ++ EA+G+ V VPYRKI +P V + G+P + FK P + ++RI
Sbjct: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412
Query: 889 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 934
L+ I F + R F + + E P SAE S+ V
Sbjct: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462
>gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo
sapiens]
Length = 944
Score = 379 bits (973), Expect = e-105
Identities = 299/970 (30%), Positives = 461/970 (47%), Gaps = 186/970 (19%)
Query: 22 VVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCV 81
++T L+SAL+SMC L+K AEVAC+AV++ FVVGTE+GR F+N RK+ Q DF+++C
Sbjct: 30 IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89
Query: 82 EEEEKAAEMHKMKSTTQAN-------RMSVD-AVEIETLRKTVEDYFCFCYGKALGKSTV 133
K E K + R S++ ++ LRK VE+ F Y +ALG+++V
Sbjct: 90 GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149
Query: 134 VPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFLEPKK 193
VP+PYE++LR+ + VQGLPEG+AF+ P YD L ILE+ I F +KRP +
Sbjct: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLED--- 206
Query: 194 HVGGR--VMVTDADRSILSPGGS--CG----PIKVKTEPTEDSGISLEMAAVTVKEESED 245
GGR + + + L P GS CG KV + + S MA+
Sbjct: 207 --GGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMAS--------- 255
Query: 246 PDYYQYNIQGSHHSSE--GNEGTEMEVPAEDDDYSPPSKRPKANEL-------------P 290
+ Y+ +H+ E + D S P PKA P
Sbjct: 256 ---FLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGP 312
Query: 291 QPPVPEPANAGKR---KVREFNFEKWNARITD------LRKQVEELFERKYAQAIKAKGP 341
P+ + +A KR + EKW+A I + LR+ V+ LF +YA+A+
Sbjct: 313 GGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHM 372
Query: 342 VTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKK--HELL- 398
V +PY E + + G+P+ IPF+RP TYG+P+L+RIL + I F+IK+ E +
Sbjct: 373 VPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIF 432
Query: 399 --NSTREDLQLDKPASGVKE--EWYARITKLRKMVDQLFCK-KFAEALG-STEAKAVPYQ 452
N +D +PAS ++ +R T L + K +E G T + +
Sbjct: 433 TGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLR 492
Query: 453 KFEAHPNDLYV------------EGLPENIPFRSP---SWYGIPRLEKIIQVGNRIKFVI 497
+ P DL + E + +++P P S YG+
Sbjct: 493 PIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGM----------------- 535
Query: 498 KRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQALGLTEAVKVPYP 557
E+LT PV++ I LRKQVE +FN ++A+A+G++E VKVPY
Sbjct: 536 ---EMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYS 592
Query: 558 VFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMA 617
F +PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+PEL +
Sbjct: 593 KFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPEL--------LT 644
Query: 618 SKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRG 677
+ + S +R +S P ++ ++ K +G
Sbjct: 645 EGVKEPIVDSQER------DSGDPLVDESL--------------------------KRQG 672
Query: 678 REFSFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLP 734
+ +++A ++I L+++V++LFN+K GEALG+K V+VP+ +S P +EGLP
Sbjct: 673 FQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLP 732
Query: 735 EGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVN 794
G+PFR+P TFG LE+IL KIKF + +P
Sbjct: 733 PGIPFRKPCTFGSQNLERILAVADKIKFTVTRP--------------------------- 765
Query: 795 TTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFPVKVPYR 854
Q IP D + +++ + LREQV +LF+ K+GEA+G+ PV VPY+
Sbjct: 766 -----------FQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYK 814
Query: 855 KITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVI---RPFPGLVINNQ 911
I +P V V G+P + F+ P+ +I + +IL + E ++ +I +PF + N+
Sbjct: 815 LIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPF-AEICNDA 873
Query: 912 LVDQSESEGP 921
V +S P
Sbjct: 874 KVPAKDSSIP 883
Score = 270 bits (691), Expect = 4e-72
Identities = 204/606 (33%), Positives = 291/606 (48%), Gaps = 92/606 (15%)
Query: 108 EIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDL 167
+I TLR+ V+ F Y +ALG +VPVPY K+ D AV + G+P+ + FK P Y +
Sbjct: 347 DINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGV 406
Query: 168 ATLKWILENKAGISFIIKRPF----------------LEPKKHVG------GRVMVTDAD 205
LK ILE + I FIIKR F LEP R V D
Sbjct: 407 PKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLA 466
Query: 206 RSILSPGGS----CGPIKVKTEPTEDSGISLEMAAVT-VKEESEDPDYYQYNIQG-SHHS 259
+ S GS CGP G S E+ + +K E ED D Q + S S
Sbjct: 467 GNARSDKGSMSEDCGP-----------GTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTS 515
Query: 260 SEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITD 319
E + +P+ED Y K + E A +R V + + + I
Sbjct: 516 EEMTDSMPGHLPSEDSGYGMEMLTDKG-------LSEDARPEERPVEDSHGDV----IRP 564
Query: 320 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 379
LRKQVE LF +YA+AI PV +PY F H E+L+V GLPEGI RRP+ +GI +L
Sbjct: 565 LRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLR 624
Query: 380 RILLAKERIRFVIKKHELLNSTREDLQLDK--------------PASGVKEEWYARITK- 424
+IL A I+FVIK+ ELL ++ +D G +E + AR+++
Sbjct: 625 KILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARLSRI 684
Query: 425 -----LRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYG 479
LR+ V LF KK+ EALG VPY++ +++P + +EGLP IPFR P +G
Sbjct: 685 DIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFG 744
Query: 480 IPRLEKIIQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITK--LRKQVEEI 537
LE+I+ V ++IKF + RP Q P ++D N K LR+QV+E+
Sbjct: 745 SQNLERILAVADKIKFTVTRP----------FQGLIPKPDEDDANRLGEKVILREQVKEL 794
Query: 538 FNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNK 597
FN K+ +ALGL V VPY + +P+ + V GLP+ IPFR+P + I RLE+I++
Sbjct: 795 FNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREH 854
Query: 598 IKFVVKKPELVISYLPPGMA----SKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNN 653
++ V +I+ L P +K+ K PKR R S + +++
Sbjct: 855 VRMV------IINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSS 908
Query: 654 NPQTSA 659
NP + A
Sbjct: 909 NPDSVA 914
Score = 149 bits (375), Expect = 2e-35
Identities = 118/411 (28%), Positives = 193/411 (46%), Gaps = 105/411 (25%)
Query: 422 ITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIP 481
I LRK V+ LF ++A+A+G +E VPY KF HP +L+V GLPE I R P+ +GI
Sbjct: 562 IRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIA 621
Query: 482 RLEKIIQVGNRIKFVIKRPELLTHSTTE--------------VTQPRTNTPVKEDWNVRI 527
+L KI++ N I+FVIKRPELLT E V + +E+++ R+
Sbjct: 622 KLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARL 681
Query: 528 TK------LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPT 581
++ LR+QV+++FN K+ EA+ + Y P +P++
Sbjct: 682 SRIDIANTLREQVQDLFNKKYG------EALGIKY---------------PVQVPYK--- 717
Query: 582 WFGIPRLERIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSK-- 639
RI + +I LPPG+ + +P + GS +
Sbjct: 718 --------RIKSNPGSV---------IIEGLPPGIPFR----------KPCTFGSQNLER 750
Query: 640 ----VPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQK 695
+I+ TV P + P + + + + K L+++
Sbjct: 751 ILAVADKIKFTV-----TRPFQGLIPKPDEDDANRLGEK---------------VILREQ 790
Query: 696 VENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILR 755
V+ LFNEK GEALGL + V VP+ L P+ V GLP+ +PFR P+T+ I RLEKIL+
Sbjct: 791 VKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILK 850
Query: 756 NKAKIKF-IIKKPEMF-------ETAIKESTSSKSPPRKINSSPNVNTTAS 798
+ ++ II + + F + K+S+ K ++++ +V++++S
Sbjct: 851 AREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSS 901
Score = 102 bits (255), Expect = 1e-21
Identities = 109/410 (26%), Positives = 172/410 (41%), Gaps = 80/410 (19%)
Query: 530 LRKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLE 589
LRK VEE+F++ +++ALG V +PY P L V+GLPEG+ FR P + L
Sbjct: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187
Query: 590 RIVRGSNKIKFVVKKPELVISYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEG 649
I+ S++I+F +K+P L ++N +L PK R G + + P++
Sbjct: 188 AILEHSHRIRFKLKRP-LEDGGRDSKALVELNGVSL-IPKGSRDCGLHGQAPKV------ 239
Query: 650 PNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALG 709
P + P PT T+ S F +S N I +LKQ+ + LG
Sbjct: 240 PPQDLP-------PTATSSSMASFL-----YSTALPNHAIRELKQEAPSC--PLAPSDLG 285
Query: 710 LKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIK-KPE 768
L + + P A + +DF ++P+ G P ++ + +K + I+ K E
Sbjct: 286 LSRPMPEPKA---TGAQDF------SDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSE 336
Query: 769 MFETAIKESTSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLR 828
++ IKE+ ED+N LR
Sbjct: 337 KWDAFIKET-----------------------EDINT---------------------LR 352
Query: 829 EQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRI 888
E V LF+ ++ EA+G+ V VPYRKI +P V + G+P + FK P + ++RI
Sbjct: 353 ECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRI 412
Query: 889 LDSAEFIKFTVIRPFPGLVINNQLVDQS----ESEGPVIQESAEPSQLEV 934
L+ I F + R F + + E P SAE S+ V
Sbjct: 413 LEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATV 462
>gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo
sapiens]
Length = 145
Score = 159 bits (401), Expect = 2e-38
Identities = 98/187 (52%), Positives = 111/187 (59%), Gaps = 43/187 (22%)
Query: 1 MAQVAMSTLPVEDEESSESRMVVTFLMSALESM-CKELAKSKAEVACIAVYETDVFVVGT 59
MAQV +STL +EDE+S ESRMVVTFLMSALES C + K E C +Y V+ G
Sbjct: 1 MAQVLVSTLSIEDEDSYESRMVVTFLMSALESTDCFRVWILKQE--CTLIYHKKVYNPG- 57
Query: 60 ERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDY 119
E + + N T +KTVEDY
Sbjct: 58 -----------------------------ESDECRCCRNGN----------TRKKTVEDY 78
Query: 120 FCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAG 179
FCFC KAL K T VPVPYEKML+DQSA++VQGLPEGVAFKHPENYDLATL+WILE AG
Sbjct: 79 FCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAG 138
Query: 180 ISFIIKR 186
ISFIIKR
Sbjct: 139 ISFIIKR 145
Score = 50.4 bits (119), Expect = 8e-06
Identities = 27/74 (36%), Positives = 39/74 (52%)
Query: 426 RKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEK 485
+K V+ FC +AL VPY+K + L V+GLPE + F+ P Y + LE
Sbjct: 72 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131
Query: 486 IIQVGNRIKFVIKR 499
I++ I F+IKR
Sbjct: 132 ILEYTAGISFIIKR 145
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/74 (39%), Positives = 38/74 (51%)
Query: 693 KQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEK 752
K+ VE+ F C +AL V VP+ V+GLPEGV F+ P + + LE
Sbjct: 72 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131
Query: 753 ILRNKAKIKFIIKK 766
IL A I FIIK+
Sbjct: 132 ILEYTAGISFIIKR 145
Score = 47.0 bits (110), Expect = 9e-05
Identities = 26/74 (35%), Positives = 38/74 (51%)
Query: 321 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 380
+K VE+ F +A++ V +PY L V+GLPEG+ F+ P Y + LE
Sbjct: 72 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131
Query: 381 ILLAKERIRFVIKK 394
IL I F+IK+
Sbjct: 132 ILEYTAGISFIIKR 145
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/74 (33%), Positives = 39/74 (52%)
Query: 531 RKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLER 590
+K VE+ F +AL V VPY + L V+GLPEG+ F+ P + + LE
Sbjct: 72 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131
Query: 591 IVRGSNKIKFVVKK 604
I+ + I F++K+
Sbjct: 132 ILEYTAGISFIIKR 145
Score = 42.0 bits (97), Expect = 0.003
Identities = 22/74 (29%), Positives = 39/74 (52%)
Query: 828 REQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRR 887
++ V D F +A+ V VPY K+ + ++V G+P GV+FK P +++++
Sbjct: 72 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131
Query: 888 ILDSAEFIKFTVIR 901
IL+ I F + R
Sbjct: 132 ILEYTAGISFIIKR 145
>gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]
Length = 298
Score = 131 bits (330), Expect = 3e-30
Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)
Query: 725 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 776
PE+ +V GLPEG+ RRP+ FGI +L KIL I+F+IK+P++ +KE
Sbjct: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
Query: 777 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 835
S+ SPP + P + + ++ + ++ + RL +++ A LREQV +LF
Sbjct: 63 ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118
Query: 836 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 895
++ +GEA+G+ +PV+VPY+ I NPG ++++ +PPG+ F+ P ++ RIL A I
Sbjct: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176
Query: 896 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 928
FTV RPF GL+ D + ++QE +
Sbjct: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209
Score = 111 bits (278), Expect = 3e-24
Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)
Query: 457 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 509
HP +L+V GLPE I R P+ +GI +L KI++ N I+FVIKRP+LLT E
Sbjct: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
Query: 510 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 541
V + +E+++ R+ + LR+QV+E+FN
Sbjct: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
Query: 542 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 601
+ +ALG+ V+VPY +SNP + +E LP GI FR P FG LERI+ +NKI F
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
Query: 602 VKKP 605
V +P
Sbjct: 180 VTRP 183
Score = 107 bits (268), Expect = 4e-23
Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)
Query: 352 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 400
H E+L+V GLPEGI RRP+ +GI +L +IL A I+FVIK+ +LL
Sbjct: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
Query: 401 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 436
T L PA G +E + AR+ + LR+ V +LF K
Sbjct: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
Query: 437 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 496
+ EALG VPY+ +++P + +E LP I FR P +G LE+I+ + N+I F
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
Query: 497 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 550
+ RP Q P ++D N + L++QV+E+FN K++Q L L +
Sbjct: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224
Score = 101 bits (251), Expect = 4e-21
Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)
Query: 562 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 620
+PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+P+L+ + P + S+
Sbjct: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
Query: 621 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 680
+L P +S+ P + ++ K +G +
Sbjct: 62 TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95
Query: 681 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 737
+++A +I L+++V+ LFN+ GEALG+K V+VP+ +S P +E LP G+
Sbjct: 96 NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155
Query: 738 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 797
FR+P FG LE+IL KI F + +P F+ I++
Sbjct: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191
Query: 798 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 843
+DD RL +V L+EQV +LF+ K+ + +
Sbjct: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220
Score = 65.1 bits (157), Expect = 3e-10
Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)
Query: 277 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 333
+SPP+ P+ + P + KR+ + N++ RI LR+QV+ELF + Y
Sbjct: 68 FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123
Query: 334 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 393
+A+ K PV +PY +S+ + +E LP GI FR+P +G LERIL +I F +
Sbjct: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181
Query: 394 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 441
+ L+ ED D G L++ V +LF +K+++ L
Sbjct: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220
Score = 49.3 bits (116), Expect = 2e-05
Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
TLR+ V++ F YG+ALG V VPY+ + + +++++ LP G+ F+ P + L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
Query: 171 KWILENKAGISFIIKRPF 188
+ IL I+F + RPF
Sbjct: 167 ERILAMANKITFTVTRPF 184
Score = 38.9 bits (89), Expect = 0.023
Identities = 19/40 (47%), Positives = 25/40 (62%)
Query: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189
V GLPEG++ + P + +A L ILE I F+IKRP L
Sbjct: 8 VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47
Score = 33.5 bits (75), Expect = 0.98
Identities = 14/45 (31%), Positives = 29/45 (64%)
Query: 858 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 902
++P + V G+P G+S + P+ I+ + +IL+++ I+F + RP
Sbjct: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45
>gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]
Length = 265
Score = 131 bits (330), Expect = 3e-30
Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)
Query: 725 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 776
PE+ +V GLPEG+ RRP+ FGI +L KIL I+F+IK+P++ +KE
Sbjct: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
Query: 777 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 835
S+ SPP + P + + ++ + ++ + RL +++ A LREQV +LF
Sbjct: 63 ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118
Query: 836 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 895
++ +GEA+G+ +PV+VPY+ I NPG ++++ +PPG+ F+ P ++ RIL A I
Sbjct: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176
Query: 896 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 928
FTV RPF GL+ D + ++QE +
Sbjct: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209
Score = 111 bits (278), Expect = 3e-24
Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)
Query: 457 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 509
HP +L+V GLPE I R P+ +GI +L KI++ N I+FVIKRP+LLT E
Sbjct: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
Query: 510 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 541
V + +E+++ R+ + LR+QV+E+FN
Sbjct: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
Query: 542 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 601
+ +ALG+ V+VPY +SNP + +E LP GI FR P FG LERI+ +NKI F
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
Query: 602 VKKP 605
V +P
Sbjct: 180 VTRP 183
Score = 107 bits (268), Expect = 4e-23
Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)
Query: 352 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 400
H E+L+V GLPEGI RRP+ +GI +L +IL A I+FVIK+ +LL
Sbjct: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
Query: 401 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 436
T L PA G +E + AR+ + LR+ V +LF K
Sbjct: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
Query: 437 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 496
+ EALG VPY+ +++P + +E LP I FR P +G LE+I+ + N+I F
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
Query: 497 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 550
+ RP Q P ++D N + L++QV+E+FN K++Q L L +
Sbjct: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224
Score = 101 bits (251), Expect = 4e-21
Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)
Query: 562 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 620
+PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+P+L+ + P + S+
Sbjct: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
Query: 621 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 680
+L P +S+ P + ++ K +G +
Sbjct: 62 TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95
Query: 681 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 737
+++A +I L+++V+ LFN+ GEALG+K V+VP+ +S P +E LP G+
Sbjct: 96 NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155
Query: 738 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 797
FR+P FG LE+IL KI F + +P F+ I++
Sbjct: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191
Query: 798 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 843
+DD RL +V L+EQV +LF+ K+ + +
Sbjct: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220
Score = 65.1 bits (157), Expect = 3e-10
Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)
Query: 277 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 333
+SPP+ P+ + P + KR+ + N++ RI LR+QV+ELF + Y
Sbjct: 68 FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123
Query: 334 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 393
+A+ K PV +PY +S+ + +E LP GI FR+P +G LERIL +I F +
Sbjct: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181
Query: 394 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 441
+ L+ ED D G L++ V +LF +K+++ L
Sbjct: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220
Score = 49.3 bits (116), Expect = 2e-05
Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
TLR+ V++ F YG+ALG V VPY+ + + +++++ LP G+ F+ P + L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
Query: 171 KWILENKAGISFIIKRPF 188
+ IL I+F + RPF
Sbjct: 167 ERILAMANKITFTVTRPF 184
Score = 38.9 bits (89), Expect = 0.023
Identities = 19/40 (47%), Positives = 25/40 (62%)
Query: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189
V GLPEG++ + P + +A L ILE I F+IKRP L
Sbjct: 8 VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47
Score = 33.5 bits (75), Expect = 0.98
Identities = 14/45 (31%), Positives = 29/45 (64%)
Query: 858 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 902
++P + V G+P G+S + P+ I+ + +IL+++ I+F + RP
Sbjct: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45
>gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]
Length = 265
Score = 131 bits (330), Expect = 3e-30
Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%)
Query: 725 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 776
PE+ +V GLPEG+ RRP+ FGI +L KIL I+F+IK+P++ +KE
Sbjct: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62
Query: 777 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 835
S+ SPP + P + + ++ + ++ + RL +++ A LREQV +LF
Sbjct: 63 ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118
Query: 836 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 895
++ +GEA+G+ +PV+VPY+ I NPG ++++ +PPG+ F+ P ++ RIL A I
Sbjct: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176
Query: 896 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 928
FTV RPF GL+ D + ++QE +
Sbjct: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209
Score = 111 bits (278), Expect = 3e-24
Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%)
Query: 457 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 509
HP +L+V GLPE I R P+ +GI +L KI++ N I+FVIKRP+LLT E
Sbjct: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
Query: 510 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 541
V + +E+++ R+ + LR+QV+E+FN
Sbjct: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
Query: 542 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 601
+ +ALG+ V+VPY +SNP + +E LP GI FR P FG LERI+ +NKI F
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
Query: 602 VKKP 605
V +P
Sbjct: 180 VTRP 183
Score = 107 bits (268), Expect = 4e-23
Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%)
Query: 352 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 400
H E+L+V GLPEGI RRP+ +GI +L +IL A I+FVIK+ +LL
Sbjct: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
Query: 401 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 436
T L PA G +E + AR+ + LR+ V +LF K
Sbjct: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121
Query: 437 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 496
+ EALG VPY+ +++P + +E LP I FR P +G LE+I+ + N+I F
Sbjct: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179
Query: 497 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 550
+ RP Q P ++D N + L++QV+E+FN K++Q L L +
Sbjct: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224
Score = 101 bits (251), Expect = 4e-21
Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%)
Query: 562 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 620
+PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+P+L+ + P + S+
Sbjct: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61
Query: 621 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 680
+L P +S+ P + ++ K +G +
Sbjct: 62 TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95
Query: 681 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 737
+++A +I L+++V+ LFN+ GEALG+K V+VP+ +S P +E LP G+
Sbjct: 96 NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155
Query: 738 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 797
FR+P FG LE+IL KI F + +P F+ I++
Sbjct: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191
Query: 798 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 843
+DD RL +V L+EQV +LF+ K+ + +
Sbjct: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220
Score = 65.1 bits (157), Expect = 3e-10
Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%)
Query: 277 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 333
+SPP+ P+ + P + KR+ + N++ RI LR+QV+ELF + Y
Sbjct: 68 FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123
Query: 334 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 393
+A+ K PV +PY +S+ + +E LP GI FR+P +G LERIL +I F +
Sbjct: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181
Query: 394 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 441
+ L+ ED D G L++ V +LF +K+++ L
Sbjct: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220
Score = 49.3 bits (116), Expect = 2e-05
Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
TLR+ V++ F YG+ALG V VPY+ + + +++++ LP G+ F+ P + L
Sbjct: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166
Query: 171 KWILENKAGISFIIKRPF 188
+ IL I+F + RPF
Sbjct: 167 ERILAMANKITFTVTRPF 184
Score = 38.9 bits (89), Expect = 0.023
Identities = 19/40 (47%), Positives = 25/40 (62%)
Query: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189
V GLPEG++ + P + +A L ILE I F+IKRP L
Sbjct: 8 VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47
Score = 33.5 bits (75), Expect = 0.98
Identities = 14/45 (31%), Positives = 29/45 (64%)
Query: 858 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 902
++P + V G+P G+S + P+ I+ + +IL+++ I+F + RP
Sbjct: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45
>gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo
sapiens]
Length = 304
Score = 129 bits (324), Expect = 1e-29
Identities = 62/75 (82%), Positives = 67/75 (89%)
Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
T +KTVEDYFCFC KAL K T VPVPYEKML+DQSA++VQGLPEGVAFKHPENYDLATL
Sbjct: 19 TRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATL 78
Query: 171 KWILENKAGISFIIK 185
+WILE AGISFIIK
Sbjct: 79 EWILEYTAGISFIIK 93
Score = 50.1 bits (118), Expect = 1e-05
Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 8/98 (8%)
Query: 693 KQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEK 752
K+ VE+ F C +AL V VP+ V+GLPEGV F+ P + + LE
Sbjct: 21 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 753 ILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSS 790
IL A I FIIK ++PP ++N +
Sbjct: 81 ILEYTAGISFIIKS--------SGEPQGRTPPLRLNQA 110
Score = 48.5 bits (114), Expect = 3e-05
Identities = 26/73 (35%), Positives = 38/73 (52%)
Query: 426 RKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEK 485
+K V+ FC +AL VPY+K + L V+GLPE + F+ P Y + LE
Sbjct: 21 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 486 IIQVGNRIKFVIK 498
I++ I F+IK
Sbjct: 81 ILEYTAGISFIIK 93
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/73 (35%), Positives = 37/73 (50%)
Query: 321 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 380
+K VE+ F +A++ V +PY L V+GLPEG+ F+ P Y + LE
Sbjct: 21 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 381 ILLAKERIRFVIK 393
IL I F+IK
Sbjct: 81 ILEYTAGISFIIK 93
Score = 44.7 bits (104), Expect = 4e-04
Identities = 25/73 (34%), Positives = 38/73 (52%)
Query: 531 RKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLER 590
+K VE+ F +AL V VPY + L V+GLPEG+ F+ P + + LE
Sbjct: 21 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 591 IVRGSNKIKFVVK 603
I+ + I F++K
Sbjct: 81 ILEYTAGISFIIK 93
Score = 41.2 bits (95), Expect = 0.005
Identities = 21/72 (29%), Positives = 38/72 (52%)
Query: 828 REQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRR 887
++ V D F +A+ V VPY K+ + ++V G+P GV+FK P +++++
Sbjct: 21 KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 888 ILDSAEFIKFTV 899
IL+ I F +
Sbjct: 81 ILEYTAGISFII 92
>gi|239752592 PREDICTED: hypothetical protein XP_002348308, partial
[Homo sapiens]
Length = 94
Score = 129 bits (323), Expect = 2e-29
Identities = 62/76 (81%), Positives = 67/76 (88%)
Query: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170
T +KTVEDYFCFC K L K T VPVPYEKML+DQSA++VQGLPEGVAFKHPENYDLATL
Sbjct: 19 TRKKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATL 78
Query: 171 KWILENKAGISFIIKR 186
+WILE AGISFIIKR
Sbjct: 79 EWILEYTAGISFIIKR 94
Score = 48.9 bits (115), Expect = 2e-05
Identities = 26/74 (35%), Positives = 38/74 (51%)
Query: 426 RKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEK 485
+K V+ FC + L VPY+K + L V+GLPE + F+ P Y + LE
Sbjct: 21 KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 486 IIQVGNRIKFVIKR 499
I++ I F+IKR
Sbjct: 81 ILEYTAGISFIIKR 94
Score = 47.0 bits (110), Expect = 9e-05
Identities = 28/74 (37%), Positives = 37/74 (50%)
Query: 693 KQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEK 752
K+ VE+ F C + L V VP+ V+GLPEGV F+ P + + LE
Sbjct: 21 KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 753 ILRNKAKIKFIIKK 766
IL A I FIIK+
Sbjct: 81 ILEYTAGISFIIKR 94
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/74 (33%), Positives = 37/74 (50%)
Query: 321 RKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLER 380
+K VE+ F + ++ V +PY L V+GLPEG+ F+ P Y + LE
Sbjct: 21 KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 381 ILLAKERIRFVIKK 394
IL I F+IK+
Sbjct: 81 ILEYTAGISFIIKR 94
Score = 43.9 bits (102), Expect = 7e-04
Identities = 24/74 (32%), Positives = 38/74 (51%)
Query: 531 RKQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLER 590
+K VE+ F + L V VPY + L V+GLPEG+ F+ P + + LE
Sbjct: 21 KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80
Query: 591 IVRGSNKIKFVVKK 604
I+ + I F++K+
Sbjct: 81 ILEYTAGISFIIKR 94
Score = 40.0 bits (92), Expect = 0.010
Identities = 18/53 (33%), Positives = 31/53 (58%)
Query: 849 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIR 901
V VPY K+ + ++V G+P GV+FK P +++++ IL+ I F + R
Sbjct: 42 VPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIKR 94
>gi|239740995 PREDICTED: hypothetical protein XP_002342058 [Homo
sapiens]
Length = 361
Score = 113 bits (283), Expect = 7e-25
Identities = 76/187 (40%), Positives = 94/187 (50%), Gaps = 40/187 (21%)
Query: 282 KRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQAIKAKGP 341
++ K NE PQPPVPEPANAG+RK+REFN EKWN RI DLRKQ EEL ERKY + K
Sbjct: 214 RKTKTNEPPQPPVPEPANAGERKMREFNSEKWNHRIADLRKQTEELSERKYGMSKLEKSC 273
Query: 342 VTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELLNST 401
+ ++ VE L++ G+P P G+P IL HEL+NST
Sbjct: 274 NLMFMGVYT--VELLFIMGVPWTSP-------GLPASHAILTC-------FSLHELMNST 317
Query: 402 REDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDL 461
EDLQLDK AR K + V +PY F++H D
Sbjct: 318 GEDLQLDKSTLS------ARAVKAKGPV------------------MIPYPFFQSHVEDF 353
Query: 462 YVEGLPE 468
Y E LP+
Sbjct: 354 YAEALPK 360
Score = 31.6 bits (70), Expect = 3.7
Identities = 13/28 (46%), Positives = 18/28 (64%)
Query: 678 REFSFEAWNAKITDLKQKVENLFNEKCG 705
REF+ E WN +I DL+++ E L K G
Sbjct: 238 REFNSEKWNHRIADLRKQTEELSERKYG 265
Score = 31.2 bits (69), Expect = 4.8
Identities = 13/29 (44%), Positives = 18/29 (62%)
Query: 707 ALGLKQAVKVPFALFESFPEDFYVEGLPE 735
A+ K V +P+ F+S EDFY E LP+
Sbjct: 332 AVKAKGPVMIPYPFFQSHVEDFYAEALPK 360
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo
sapiens]
Length = 561
Score = 45.8 bits (107), Expect = 2e-04
Identities = 29/41 (70%), Positives = 32/41 (78%), Gaps = 7/41 (17%)
Query: 1 MAQVAMSTLP------VEDEESSESRMVVTFLMSALESMCK 35
MAQVA+STLP VEDEES ESRMVVTFL SAL+SM +
Sbjct: 1 MAQVAVSTLPIEDEESVEDEESLESRMVVTFL-SALDSMVR 40
>gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]
Length = 490
Score = 36.6 bits (83), Expect = 0.12
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 16/87 (18%)
Query: 214 SCGPIKVKTEPTEDSGISLEMAA-----------VTVKEESEDPDYYQYNIQGSHHSSEG 262
SCG V +P ED S ++ ++ S D D+Y++ +GS SEG
Sbjct: 321 SCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSAD-DHYEFATKGSQEGSEG 379
Query: 263 NEGT----EMEVPAEDDDYSPPSKRPK 285
+EG+ E E+DD K PK
Sbjct: 380 SEGSFRSHESPSDTEEDDRKHSQKEPK 406
>gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]
Length = 468
Score = 36.6 bits (83), Expect = 0.12
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 16/87 (18%)
Query: 214 SCGPIKVKTEPTEDSGISLEMAA-----------VTVKEESEDPDYYQYNIQGSHHSSEG 262
SCG V +P ED S ++ ++ S D D+Y++ +GS SEG
Sbjct: 299 SCGSPVVSGDPKEDHNYSSAKSSNARSTSPTSDSISSSSSSAD-DHYEFATKGSQEGSEG 357
Query: 263 NEGT----EMEVPAEDDDYSPPSKRPK 285
+EG+ E E+DD K PK
Sbjct: 358 SEGSFRSHESPSDTEEDDRKHSQKEPK 384
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 36.2 bits (82), Expect = 0.15
Identities = 130/591 (21%), Positives = 215/591 (36%), Gaps = 122/591 (20%)
Query: 267 EMEVPAEDDDYSPPSKR--PKANELPQP----PVPEPANAGKRKVREFNF------EKWN 314
E EVP E++ Y P + P+ LP+ PVP P K+KV E E
Sbjct: 10151 EEEVPPEEE-YVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPP 10209
Query: 315 ARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYG 374
A++ ++ K+VEE + I K +P + + E+ E E IP PS
Sbjct: 10210 AKVPEVPKKVEE------KRIILPKEEEVLPVEVTEEPEEEPISE---EEIPEEPPS--- 10257
Query: 375 IPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 434
I +E + A R+ VIKK T +++ P + V
Sbjct: 10258 IEEVEEV--APPRVPEVIKKAVPEAPTPVPKKVEAPPAKVS------------------- 10296
Query: 435 KKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRS---------PSWYGIPRLEK 485
KK E E VP QK EA P V +P+ +P + P G LE+
Sbjct: 10297 KKIPE-----EKVPVPVQKKEAPP--AKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEE 10349
Query: 486 IIQVGNRIKFVIKRP---ELLTHSTTEVTQPRTNTPVKEDWN----------VRITKLR- 531
+ V R + V+K E++ E+ + V+E + +++ + R
Sbjct: 10350 KVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRV 10409
Query: 532 ------KQVEEIFNLKFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGI 585
++V + + A+ + + E K P E + + + + P + R +
Sbjct: 10410 EEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKV 10469
Query: 586 PRLERIVRGSNKIKFVVK---KPELVISYLPPGMASKINTKALQSPKRPRSP------GS 636
P + + + K++ + P V LPP + K+P +P
Sbjct: 10470 PEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAP 10529
Query: 637 NSKVPEIEVTV------EGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWNAKIT 690
VPE +V V E P P+ P + +P KP +
Sbjct: 10530 KEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKP----------ESPPP 10579
Query: 691 DLKQKVENLFNEKCGEALGLKQ----AVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFG 746
++ + + + EK A K+ VKVP A E PE V P P P+
Sbjct: 10580 EVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEK-KVPVPPPKKPEVPPTK-- 10636
Query: 747 IPRLEKILRNKAKIKFII------KKPEMFETAIKESTSSKSPPRKINSSP 791
+P + K+ + K+ I PE+FE E + + PP ++ P
Sbjct: 10637 VPEVPKVAVPEKKVPEAIPPKPESPPPEVFEE--PEEVALEEPPAEVVEEP 10685
Score = 30.4 bits (67), Expect = 8.3
Identities = 34/116 (29%), Positives = 50/116 (43%), Gaps = 10/116 (8%)
Query: 200 MVTDADRSILSPGGSCGPIKVKTEPTE-DSGISLEMAAVTVK--EESEDPDYY------Q 250
+V + SI +P PIK T E + +LE AV+V+ EE E+ + Y +
Sbjct: 9699 VVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEE 9758
Query: 251 YNIQGSHHSSEGNEGTEMEVPAEDDDY-SPPSKRPKANELPQPPVPEPANAGKRKV 305
Y + E E E E E ++Y + P K +P+ PVP A KV
Sbjct: 9759 YEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKV 9814
>gi|28872812 MORC family CW-type zinc finger 3 [Homo sapiens]
Length = 939
Score = 36.2 bits (82), Expect = 0.15
Identities = 24/105 (22%), Positives = 51/105 (48%), Gaps = 7/105 (6%)
Query: 586 PRLERIVRGSNKIKFVVKKPELV------ISYLPPGMASKINTKALQS-PKRPRSPGSNS 638
P E+ + +NK KF +++PE++ + + P +++ + +S P+R S G+NS
Sbjct: 460 PTYEKTYKKTNKEKFRIRQPEMIPRINAELLFRPTALSTPSFSSPKESVPRRHLSEGTNS 519
Query: 639 KVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFE 683
+ + P + P++++++ T S + K R FE
Sbjct: 520 YATRLLNNHQVPPQSEPESNSLKRRLSTRSSILNAKNRRLSSQFE 564
>gi|4503579 erythrocyte membrane protein band 4.1-like 2 isoform a
[Homo sapiens]
Length = 1005
Score = 35.8 bits (81), Expect = 0.20
Identities = 29/105 (27%), Positives = 45/105 (42%), Gaps = 4/105 (3%)
Query: 198 RVMVTDADRSILSPGGSCGPIKVKTEP-TEDSGISLEMAAVTVKEESEDPDYYQYNIQGS 256
RV+ + + +SPG G I+ K EP T+ SL + + ESE+ D +Y +
Sbjct: 703 RVITEEMNGKEISPGSGPGEIR-KVEPVTQKDSTSLSSESSSSSSESEEEDVGEY--RPH 759
Query: 257 HHSSEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANAG 301
H +EG E E E ++ P+ + E P AG
Sbjct: 760 HRVTEGTIREEQEYEEEVEEEPRPAAKVVEREEAVPEASPVTQAG 804
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 34.3 bits (77), Expect = 0.57
Identities = 33/138 (23%), Positives = 58/138 (42%), Gaps = 7/138 (5%)
Query: 210 SPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSE-GNEGTEM 268
SP P K K+ PT++ S E A KEE++ P+ + ++ S E +
Sbjct: 628 SPAEVKSPEKAKS-PTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKA 686
Query: 269 EVPAEDDDYSPPSKRPKANELPQPPVPEPANAGKR-----KVREFNFEKWNARITDLRKQ 323
E + + SP + K+ E + PV E A + ++ K EK + + + K
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKS 746
Query: 324 VEELFERKYAQAIKAKGP 341
E+ + A+ + K P
Sbjct: 747 PEKAKSPEKAKTLDVKSP 764
>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
Length = 1388
Score = 33.9 bits (76), Expect = 0.75
Identities = 16/49 (32%), Positives = 24/49 (48%)
Query: 616 MASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPT 664
M +K++ K L P + PG S P +T G N+P + + TPT
Sbjct: 710 MRAKVSGKMLSQPMSTQDPGGMSMSPMKSMTAGGMQMNSPTSDVMSTPT 758
>gi|239757124 PREDICTED: hypothetical protein [Homo sapiens]
Length = 106
Score = 33.5 bits (75), Expect = 0.98
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Query: 121 CFCYGKALGKSTVVPVPYE--KMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKA 178
C Y + L S ++P E K R ++ +G+ + KH E DL L W++E
Sbjct: 5 CLLYERFLRTSPLLPTCGEDNKEKRSRNQKASRGMRCRIPIKHSEGADLTVLVWVVERDI 64
Query: 179 GISFIIKRPFLEPKKH 194
+ + PF P H
Sbjct: 65 SV-LSVSTPFRIPLNH 79
>gi|113428448 PREDICTED: hypothetical protein [Homo sapiens]
Length = 90
Score = 33.5 bits (75), Expect = 0.98
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Query: 121 CFCYGKALGKSTVVPVPYE--KMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKA 178
C Y + L S ++P E K R ++ +G+ + KH E DL L W++E
Sbjct: 5 CLLYERFLRTSPLLPTCGEDNKEKRSRNQKASRGMRCRIPIKHSEGADLTVLVWVVERDI 64
Query: 179 GISFIIKRPFLEPKKH 194
+ + PF P H
Sbjct: 65 SV-LSVSTPFRIPLNH 79
>gi|169213522 PREDICTED: hypothetical protein [Homo sapiens]
Length = 106
Score = 33.5 bits (75), Expect = 0.98
Identities = 21/76 (27%), Positives = 33/76 (43%), Gaps = 3/76 (3%)
Query: 121 CFCYGKALGKSTVVPVPYE--KMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKA 178
C Y + L S ++P E K R ++ +G+ + KH E DL L W++E
Sbjct: 5 CLLYERFLRTSPLLPTCGEDNKEKRSRNQKASRGMRCRIPIKHSEGADLTVLVWVVERDI 64
Query: 179 GISFIIKRPFLEPKKH 194
+ + PF P H
Sbjct: 65 SV-LSVSTPFRIPLNH 79
>gi|226491199 coiled-coil domain containing 38 [Homo sapiens]
Length = 563
Score = 32.3 bits (72), Expect = 2.2
Identities = 22/72 (30%), Positives = 34/72 (47%), Gaps = 5/72 (6%)
Query: 80 CVEEEEKAAEMHKMKSTTQANRMSVDAVE--IETLRKTVEDYFCFCYGKALGKSTVVPVP 137
CV EEEKAAE+ + DA E I++L K + + C G A P
Sbjct: 399 CVREEEKAAELQLKSKLFSFGEFNSDAQEILIDSLSKKITQVYKVCIGDAEDDGL---NP 455
Query: 138 YEKMLRDQSAVV 149
+K+++ +S +V
Sbjct: 456 IQKLVKVESRLV 467
>gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]
Length = 611
Score = 32.3 bits (72), Expect = 2.2
Identities = 15/56 (26%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
Query: 631 PRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREFSFEAWN 686
PR+P N+ E ++ + PN ++ ++ A + +GS++ +P+ R F E++N
Sbjct: 126 PRTPTGNAPSSESDIDISSPNVSHDESIAKDMSLKDSGSDLSHRPKRRRF-HESYN 180
>gi|146134388 YLP motif containing 1 [Homo sapiens]
Length = 2146
Score = 32.3 bits (72), Expect = 2.2
Identities = 18/52 (34%), Positives = 22/52 (42%), Gaps = 3/52 (5%)
Query: 250 QYNIQGSHHSSEGNEGT---EMEVPAEDDDYSPPSKRPKANELPQPPVPEPA 298
QY Q HH +G G E+E P E P S P + PP P P+
Sbjct: 122 QYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPS 173
>gi|91199550 CD68 antigen isoform B [Homo sapiens]
Length = 327
Score = 32.0 bits (71), Expect = 2.8
Identities = 26/124 (20%), Positives = 43/124 (34%), Gaps = 5/124 (4%)
Query: 202 TDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSE 261
T R+ + S GP PT S VTV S Q +H +
Sbjct: 32 TTTHRTTTTGTTSHGPTTATHNPTTTSH-----GNVTVHPTSNSTATSQGPSTATHSPAT 86
Query: 262 GNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARITDLR 321
+ G P + + P A+ P PP P P+ K + ++ + + L+
Sbjct: 87 TSHGNATVHPTSNSTATSPGFTSSAHPEPPPPSPSPSPTSKETIGDYTWTNGSQPCVHLQ 146
Query: 322 KQVE 325
Q++
Sbjct: 147 AQIQ 150
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.133 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,547,028
Number of Sequences: 37866
Number of extensions: 1906357
Number of successful extensions: 6148
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 5781
Number of HSP's gapped (non-prelim): 227
length of query: 957
length of database: 18,247,518
effective HSP length: 112
effective length of query: 845
effective length of database: 14,006,526
effective search space: 11835514470
effective search space used: 11835514470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.