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Search of human proteins with 169217383
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169217383 PREDICTED: similar to coiled-coil domain
containing 29 [Homo sapiens]
(185 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169217383 PREDICTED: similar to coiled-coil domain containing... 365 e-102
gi|169178850 PREDICTED: similar to coiled-coil domain containing... 300 4e-82
gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens] 286 9e-78
gi|149363632 coiled-coil domain containing 29 [Homo sapiens] 276 7e-75
gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo ... 275 1e-74
gi|239742325 PREDICTED: similar to coiled-coil domain containing... 259 1e-69
gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo ... 242 1e-64
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 222 2e-58
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 222 2e-58
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 222 2e-58
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 220 6e-58
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 220 6e-58
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 220 6e-58
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens] 169 1e-42
gi|154354990 ankyrin repeat domain 26 [Homo sapiens] 148 3e-36
gi|169169660 PREDICTED: hypothetical protein [Homo sapiens] 103 6e-23
gi|169169929 PREDICTED: hypothetical protein [Homo sapiens] 103 6e-23
gi|149363642 coiled-coil domain containing 144A [Homo sapiens] 84 5e-17
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 47 7e-06
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 47 9e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 47 9e-06
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 46 2e-05
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 46 2e-05
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens] 46 2e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 45 3e-05
gi|50083279 centrosome protein 4 [Homo sapiens] 45 4e-05
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 44 8e-05
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 44 1e-04
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 44 1e-04
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 43 2e-04
>gi|169217383 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 185
Score = 365 bits (938), Expect = e-102
Identities = 185/185 (100%), Positives = 185/185 (100%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ
Sbjct: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ
Sbjct: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLESTGKPYLTKRIFNHKVLR 180
AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLESTGKPYLTKRIFNHKVLR
Sbjct: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLESTGKPYLTKRIFNHKVLR 180
Query: 181 KNCMI 185
KNCMI
Sbjct: 181 KNCMI 185
>gi|169178850 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 197
Score = 300 bits (769), Expect = 4e-82
Identities = 153/164 (93%), Positives = 159/164 (96%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDL EEEAVSSKCVNL+KDNQ
Sbjct: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
VIQQELLSMKKVQQECEKLEE++KMLEEEILNLKTHMEN+MVELSKLQEYKSE DERA+Q
Sbjct: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLEST 164
AVEKL+EIHLQME DCVEQIIRETKRTVAVLDTC HLLSSLEST
Sbjct: 121 AVEKLKEIHLQMELDCVEQIIRETKRTVAVLDTCCHLLSSLEST 164
>gi|239750312 PREDICTED: similar to hCG1744891 [Homo sapiens]
Length = 154
Score = 286 bits (731), Expect = 9e-78
Identities = 145/147 (98%), Positives = 146/147 (99%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ
Sbjct: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSE DERAIQ
Sbjct: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSEPDERAIQ 120
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRT 147
AVEKLEEIHLQMEADCVEQIIRETKR+
Sbjct: 121 AVEKLEEIHLQMEADCVEQIIRETKRS 147
>gi|149363632 coiled-coil domain containing 29 [Homo sapiens]
Length = 161
Score = 276 bits (706), Expect = 7e-75
Identities = 139/161 (86%), Positives = 150/161 (93%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLNVFGNEDF CH DLKTDQLKMDILIKKLKQKFDDLT ++EA+SSKCVNLAKDNQ
Sbjct: 1 MTINMLNVFGNEDFDCHGDLKTDQLKMDILIKKLKQKFDDLTAQKEALSSKCVNLAKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
V+QQE LSMKKVQQ+CEKLEEDKKML+EEILNLKTHMENN VE+SKLQEYK E DE+A+Q
Sbjct: 61 VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVEISKLQEYKLELDEKAMQ 120
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSL 161
AVEKLEEIHLQME DCVEQI RETKR VAVL+TCS LL+SL
Sbjct: 121 AVEKLEEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 161
>gi|239743762 PREDICTED: hypothetical protein XP_002342954 [Homo
sapiens]
Length = 183
Score = 275 bits (704), Expect = 1e-74
Identities = 139/161 (86%), Positives = 149/161 (92%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLNVFGNEDF CH DLK DQLKMDILIKKLKQKFDDLT E+EA+SSKCVNLAKDNQ
Sbjct: 23 MTINMLNVFGNEDFDCHGDLKADQLKMDILIKKLKQKFDDLTAEKEALSSKCVNLAKDNQ 82
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
V+QQE LSMKKVQQ+CEKLEEDKKML+EEILNLKTHMENN VELSKLQEYK E DE+A+Q
Sbjct: 83 VLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVELSKLQEYKLELDEKAMQ 142
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSL 161
AVEK+EEIHLQME DCVEQI RETKR VAVL+TCS LL+SL
Sbjct: 143 AVEKIEEIHLQMELDCVEQITRETKRIVAVLNTCSRLLTSL 183
>gi|239742325 PREDICTED: similar to coiled-coil domain containing 29
[Homo sapiens]
Length = 150
Score = 259 bits (661), Expect = 1e-69
Identities = 129/149 (86%), Positives = 142/149 (95%)
Query: 37 KFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTH 96
+FDDL EEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEE++KMLEEEILNLKTH
Sbjct: 2 RFDDLMAEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTH 61
Query: 97 MENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSH 156
MEN++VELS+LQ+YKSE DERA+QAVEKL+EI+L ME DC+EQIIRETKRT AVLDTCSH
Sbjct: 62 MENSIVELSELQDYKSELDERAMQAVEKLKEINLHMEPDCIEQIIRETKRTAAVLDTCSH 121
Query: 157 LLSSLESTGKPYLTKRIFNHKVLRKNCMI 185
LLSSLESTGKP+LTKRIFNH VL+KNCMI
Sbjct: 122 LLSSLESTGKPHLTKRIFNHNVLKKNCMI 150
>gi|239747109 PREDICTED: hypothetical protein XP_002344496 [Homo
sapiens]
Length = 146
Score = 242 bits (618), Expect = 1e-64
Identities = 124/139 (89%), Positives = 132/139 (94%), Gaps = 2/139 (1%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDL EEEAVSSKCVNL+KDNQ
Sbjct: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLMAEEEAVSSKCVNLSKDNQ 60
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
VIQQELLSMKKVQQECEKLEE++KMLEEEILNLKTHMEN+MVELSKLQEYKSE DERA+Q
Sbjct: 61 VIQQELLSMKKVQQECEKLEENQKMLEEEILNLKTHMENSMVELSKLQEYKSELDERAMQ 120
Query: 121 AVEKLEEIHLQMEADCVEQ 139
AVEKL+EIHLQ+ C+ Q
Sbjct: 121 AVEKLKEIHLQV--TCLNQ 137
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 222 bits (565), Expect = 2e-58
Identities = 113/162 (69%), Positives = 131/162 (80%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKFDDL E+EAVSSKCVNLAKDN+
Sbjct: 821 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 880
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
V+ QELLSM KVQ++CEKLE+DKKMLEE++LNLKTHME +MVEL K+QEYKSE DERA+Q
Sbjct: 881 VLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQ 940
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLE 162
A+EKLEEIHLQ +A+ +Q+ + K A L L +E
Sbjct: 941 AIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVE 982
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 222 bits (565), Expect = 2e-58
Identities = 113/162 (69%), Positives = 131/162 (80%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKFDDL E+EAVSSKCVNLAKDN+
Sbjct: 850 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 909
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
V+ QELLSM KVQ++CEKLE+DKKMLEE++LNLKTHME +MVEL K+QEYKSE DERA+Q
Sbjct: 910 VLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQ 969
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLE 162
A+EKLEEIHLQ +A+ +Q+ + K A L L +E
Sbjct: 970 AIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVE 1011
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 222 bits (565), Expect = 2e-58
Identities = 113/162 (69%), Positives = 131/162 (80%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKFDDL E+EAVSSKCVNLAKDN+
Sbjct: 850 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFDDLMAEKEAVSSKCVNLAKDNE 909
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
V+ QELLSM KVQ++CEKLE+DKKMLEE++LNLKTHME +MVEL K+QEYKSE DERA+Q
Sbjct: 910 VLHQELLSMGKVQEKCEKLEKDKKMLEEKVLNLKTHMEKDMVELGKVQEYKSELDERAMQ 969
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLE 162
A+EKLEEIHLQ +A+ +Q+ + K A L L +E
Sbjct: 970 AIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVE 1011
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 220 bits (560), Expect = 6e-58
Identities = 111/162 (68%), Positives = 130/162 (80%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKF+DL E+EAVSS+CVNLAKDN+
Sbjct: 820 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 879
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
V+ QELLSM+ VQ++CEKLE+DKKMLEEE+LNLKTHME +MVEL KLQEYKSE DERA+Q
Sbjct: 880 VLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQ 939
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLE 162
+EKLEEIHLQ +A+ +Q+ + K A L L +E
Sbjct: 940 EIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVE 981
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 220 bits (560), Expect = 6e-58
Identities = 111/162 (68%), Positives = 130/162 (80%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKF+DL E+EAVSS+CVNLAKDN+
Sbjct: 713 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 772
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
V+ QELLSM+ VQ++CEKLE+DKKMLEEE+LNLKTHME +MVEL KLQEYKSE DERA+Q
Sbjct: 773 VLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQ 832
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLE 162
+EKLEEIHLQ +A+ +Q+ + K A L L +E
Sbjct: 833 EIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVE 874
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 220 bits (560), Expect = 6e-58
Identities = 111/162 (68%), Positives = 130/162 (80%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MTINMLN F NEDF CH DL TDQLKMDIL KKLKQKF+DL E+EAVSS+CVNLAKDN+
Sbjct: 820 MTINMLNAFANEDFSCHGDLNTDQLKMDILFKKLKQKFNDLVAEKEAVSSECVNLAKDNE 879
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
V+ QELLSM+ VQ++CEKLE+DKKMLEEE+LNLKTHME +MVEL KLQEYKSE DERA+Q
Sbjct: 880 VLHQELLSMRNVQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQ 939
Query: 121 AVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLE 162
+EKLEEIHLQ +A+ +Q+ + K A L L +E
Sbjct: 940 EIEKLEEIHLQKQAEYEKQLEQLNKDNTASLKKKELTLKDVE 981
>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]
Length = 561
Score = 169 bits (428), Expect = 1e-42
Identities = 86/108 (79%), Positives = 98/108 (90%)
Query: 33 KLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEILN 92
+++ +FDD E+EAVSSKCVNLAK+ QV QQELLSMKKVQQECEKLEEDKKMLEEEILN
Sbjct: 443 QVESQFDDFMAEKEAVSSKCVNLAKEIQVFQQELLSMKKVQQECEKLEEDKKMLEEEILN 502
Query: 93 LKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQI 140
LKTHMEN+MVELSKLQEYKSE DERA+QAVEKLEEIHLQ +A+ +Q+
Sbjct: 503 LKTHMENSMVELSKLQEYKSELDERAMQAVEKLEEIHLQEQAEHKKQL 550
>gi|154354990 ankyrin repeat domain 26 [Homo sapiens]
Length = 1710
Score = 148 bits (373), Expect = 3e-36
Identities = 73/140 (52%), Positives = 103/140 (73%), Gaps = 1/140 (0%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
MT LN + N +F H DLKT Q +MDI I KLK K DDLT E E SKC++L NQ
Sbjct: 1369 MTRKKLNEYENGEFSFHGDLKTSQFEMDIQINKLKHKIDDLTAELETAGSKCLHLDTKNQ 1428
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQ 120
++Q+ELLSMK VQ++CEKL+++KK LE+E++NL++H+E NMVEL ++++YK E +ERA Q
Sbjct: 1429 ILQEELLSMKTVQKKCEKLQKNKKKLEQEVINLRSHIERNMVELGQVKQYKQEIEERARQ 1488
Query: 121 AV-EKLEEIHLQMEADCVEQ 139
+ EKL+E++L ++A Q
Sbjct: 1489 EIAEKLKEVNLFLQAQAASQ 1508
Score = 32.0 bits (71), Expect = 0.31
Identities = 31/113 (27%), Positives = 51/113 (45%), Gaps = 11/113 (9%)
Query: 31 IKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQEC---EKLEEDKKMLE 87
+K+ KQ+ ++ +E A K VNL Q QE L + ++E K LE
Sbjct: 1475 VKQYKQEIEERARQEIAEKLKEVNLFLQAQAASQENLEQFRENNFASMKSQMELRIKDLE 1534
Query: 88 EEILNLKTHMEN-NMVELSK-----LQEYK--SETDERAIQAVEKLEEIHLQM 132
E+ +KT E+ N EL K L+E K + + E+L E++ ++
Sbjct: 1535 SELSKIKTSQEDFNKTELEKYKQLYLEELKVRKSLSSKLTKTNERLAEVNTKL 1587
Score = 29.3 bits (64), Expect = 2.0
Identities = 25/120 (20%), Positives = 52/120 (43%), Gaps = 10/120 (8%)
Query: 16 CHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQE 75
C EDLK + K + L K +KQ + LT + + L +N ++ +L
Sbjct: 942 CFEDLKIVKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKL--------- 992
Query: 76 CEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEAD 135
E ++ K+ LE E+ + + + + + + + K E + +A ++ + +M D
Sbjct: 993 -ENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFD 1051
Score = 28.1 bits (61), Expect = 4.5
Identities = 21/84 (25%), Positives = 47/84 (55%), Gaps = 1/84 (1%)
Query: 24 QLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECE-KLEED 82
Q ++++ KK+ + EE+ +S K L ++ +++ E+ ++K QE E K ED
Sbjct: 886 QKEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFED 945
Query: 83 KKMLEEEILNLKTHMENNMVELSK 106
K+++E+ +L+ ++ N L++
Sbjct: 946 LKIVKEKNEDLQKTIKQNEETLTQ 969
>gi|169169660 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 103 bits (258), Expect = 6e-23
Identities = 56/100 (56%), Positives = 74/100 (74%), Gaps = 1/100 (1%)
Query: 32 KKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEIL 91
K L++ +L + KC+ LAK NQVIQQELLSMK+VQQ+C+KLEE K+LE+E++
Sbjct: 316 KFLRRHLMNLQQSWKLYLQKCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVV 375
Query: 92 NLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQ 131
NLKTH E NMVE ++E K + +ERA Q +EKLEEI+LQ
Sbjct: 376 NLKTH-EKNMVEFGDVEECKLQLEERAGQEIEKLEEINLQ 414
>gi|169169929 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 103 bits (258), Expect = 6e-23
Identities = 56/100 (56%), Positives = 74/100 (74%), Gaps = 1/100 (1%)
Query: 32 KKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEIL 91
K L++ +L + KC+ LAK NQVIQQELLSMK+VQQ+C+KLEE K+LE+E++
Sbjct: 316 KFLRRHLMNLQQSWKLYLQKCLYLAKKNQVIQQELLSMKEVQQKCKKLEEVNKILEQEVV 375
Query: 92 NLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQ 131
NLKTH E NMVE ++E K + +ERA Q +EKLEEI+LQ
Sbjct: 376 NLKTH-EKNMVEFGDVEECKLQLEERAGQEIEKLEEINLQ 414
>gi|149363642 coiled-coil domain containing 144A [Homo sapiens]
Length = 1427
Score = 84.3 bits (207), Expect = 5e-17
Identities = 52/145 (35%), Positives = 88/145 (60%), Gaps = 7/145 (4%)
Query: 26 KMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQ--QELLSMKKVQQECEKLEEDK 83
+MD K+ + DLT +E V S+C++L +N+V+Q Q L SMK +Q++CE L+++K
Sbjct: 1112 RMDQCEKEKAGRKIDLTEAQETVPSRCLHLDAENEVLQLQQTLFSMKAIQKQCETLQKNK 1171
Query: 84 KMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAV-EKLEEIHLQMEADCV---EQ 139
K L++E++NLK++ME NM+E K + +K +ERA + + EKL E L ++ EQ
Sbjct: 1172 KQLKQEVVNLKSYMERNMLERGKAEWHKLLIEERARKEIEEKLNEAILTLQKQAAVSHEQ 1231
Query: 140 IIRETKRTVAVLDTCSHL-LSSLES 163
+++ + + T L + LES
Sbjct: 1232 LVQLREDNTTSIKTQMELTIKDLES 1256
Score = 33.1 bits (74), Expect = 0.14
Identities = 24/95 (25%), Positives = 48/95 (50%), Gaps = 1/95 (1%)
Query: 11 NEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELL-SM 69
+ED + E++ +L++D + + KQK + EAV K NL K ++ ++ L ++
Sbjct: 819 HEDCMLQEEIALLRLEIDTIKNQNKQKEKKYFEDIEAVKEKNDNLQKIIKLNEETLTETI 878
Query: 70 KKVQQECEKLEEDKKMLEEEILNLKTHMENNMVEL 104
+ + L + K+L E+ N K + E +E+
Sbjct: 879 LQYSGQLNNLTAENKILNSELENGKQNQERLEIEM 913
Score = 28.9 bits (63), Expect = 2.6
Identities = 24/114 (21%), Positives = 52/114 (45%), Gaps = 7/114 (6%)
Query: 60 QVIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAI 119
Q+ Q E +KK + E +EE L+ E + L+ +++ + + QE S T +
Sbjct: 1019 QMYQIEQSKLKKYIAKQESVEERLSQLQSENMLLRQQLDDAHKKANS-QEKTSSTIQDQF 1077
Query: 120 QAVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLESTGKPYLTKRI 173
+ K ++A+ +QI+ ++ ++D +HL ++ K ++I
Sbjct: 1078 HSAAK------NLQAESEKQILSLQEKNKELMDEYNHLKERMDQCEKEKAGRKI 1125
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 47.4 bits (111), Expect = 7e-06
Identities = 31/140 (22%), Positives = 74/140 (52%), Gaps = 11/140 (7%)
Query: 12 EDFVCHEDLKTDQLKMDILIKKLKQKF----DDLTPEEEAVSSKCVNLAKDNQVIQQELL 67
++ + + +L+ Q K++ + KL+Q+ + + + KC + A + + +Q+++
Sbjct: 920 QETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVI 979
Query: 68 SM----KKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETD---ERAIQ 120
+ ++V+ E ++ +E+ +E+EI++LK EN + LS+L +T E+
Sbjct: 980 ELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTN 1039
Query: 121 AVEKLEEIHLQMEADCVEQI 140
AV++LE++ E + E +
Sbjct: 1040 AVKELEKLQHSTETELTEAL 1059
Score = 37.4 bits (85), Expect = 0.007
Identities = 24/112 (21%), Positives = 54/112 (48%), Gaps = 12/112 (10%)
Query: 32 KKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEIL 91
KK+ +K + + EEE + N K+N K++Q+ C + + ++L+E++
Sbjct: 375 KKVAEKLEKVQAEEEILERNLTNCEKEN----------KRLQERCGLYKSELEILKEKLR 424
Query: 92 NLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRE 143
LK N +L + SE + ++ + + + L+ E + ++I+R+
Sbjct: 425 QLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSI--LKLESELENKDEILRD 474
Score = 35.0 bits (79), Expect = 0.037
Identities = 26/132 (19%), Positives = 62/132 (46%), Gaps = 16/132 (12%)
Query: 11 NEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMK 70
N D + +T Q ++ + ++L +K + + E ++ KC L + +++++++
Sbjct: 657 NSDLKVNMAHRTSQFQL--IQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYS 714
Query: 71 KVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHL 130
+ + +LE++ E+I +L+T++ E+ A EK ++IHL
Sbjct: 715 SIAAKNAELEQELMEKNEKIRSLETNINTE--------------HEKICLAFEKAKKIHL 760
Query: 131 QMEADCVEQIIR 142
+ + +QI R
Sbjct: 761 EQHKEMEKQIER 772
Score = 31.2 bits (69), Expect = 0.53
Identities = 27/109 (24%), Positives = 53/109 (48%), Gaps = 4/109 (3%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQ 60
+ +++ + GN++ + LK ++ L K+LK K L E L + Q
Sbjct: 858 LVLHLNQLEGNKEKF-EKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQ 916
Query: 61 VIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQE 109
++QQE + +++ KLE+ LE+E L+ E++ +L K++E
Sbjct: 917 MLQQETIRNGELEDTQTKLEKQVSKLEQE---LQKQRESSAEKLRKMEE 962
Score = 29.6 bits (65), Expect = 1.5
Identities = 24/119 (20%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 27 MDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKK-- 84
+D IK L++K + L + + ++ +L + I EL + E ++
Sbjct: 227 VDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASV 286
Query: 85 -MLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIH---LQMEADCVEQ 139
+LEE+I+NL+ + L + + ++ + I+ + L+E ++++ D +EQ
Sbjct: 287 PILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQ 345
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 47.0 bits (110), Expect = 9e-06
Identities = 35/157 (22%), Positives = 76/157 (48%), Gaps = 17/157 (10%)
Query: 12 EDFVCHEDLKTDQLKMDIL------IKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQE 65
E+ + HE +K K+ + IKK + + + E + ++ +L K+N+++Q++
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Query: 66 LLSMKKVQQECEKLEEDKKMLEEEILNLKTHME---NNMVELSKLQEYKSETDERAIQAV 122
+ ++K ++ E LE++ LE E LK ++ N +L L++ S+ DE ++
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Query: 123 EKLEEI--------HLQMEADCVEQIIRETKRTVAVL 151
+E + LQ+E +E + K+ + +L
Sbjct: 708 RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL 744
Score = 41.6 bits (96), Expect = 4e-04
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECE 77
E L+ +DI ++L++ ++ + + + S+ +L +NQ +Q+ L +K + E
Sbjct: 752 ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE 811
Query: 78 KLEEDKKMLEEEILNL---KTHMENNMVELSKLQEYKSETDERAIQAVEKLEE 127
+LE++ K LE+E L K +E L + E K T E + LE+
Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK 864
Score = 35.4 bits (80), Expect = 0.028
Identities = 39/146 (26%), Positives = 71/146 (48%), Gaps = 16/146 (10%)
Query: 26 KMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDK-K 84
K++ + + K++ D+ E ++ L +DNQV+ E +M + Q E + DK
Sbjct: 324 KLESEVSRYKERLHDI----EFYKARVEELKEDNQVL-LETKTMLEDQLEGTRARSDKLH 378
Query: 85 MLEEEILNLKT-----HMENNMVELSKLQEYKSETDERAIQAVEKLEE-IHLQMEADCVE 138
LE+E L LK ME +M + K++E E + + ++E +HL E +E
Sbjct: 379 ELEKENLQLKAKLHDMEMERDM-DRKKIEELMEENMTLEMAQKQSMDESLHLGWE---LE 434
Query: 139 QIIRETKRTVAVLDTCSHLLSSLEST 164
QI R ++ + A + H ++ L S+
Sbjct: 435 QISRTSELSEAPQKSLGHEVNELTSS 460
Score = 34.3 bits (77), Expect = 0.063
Identities = 33/120 (27%), Positives = 63/120 (52%), Gaps = 12/120 (10%)
Query: 20 LKTDQLKMDILIKKLKQKFD--DLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECE 77
L+ D+ +++ K+L+Q+ + D T EE V K NL K+N+ + +E+ K+ +
Sbjct: 827 LEKDKKQLEKENKRLRQQAEIKDTTLEENNV--KIGNLEKENKTLSKEIGIYKESCVRLK 884
Query: 78 KLEEDKKMLEE----EILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
+LE++ K L + +I L T E+ + E K Q+ ++ + + +LE+I L E
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE----KLTHELEKIGLNKE 940
Score = 33.5 bits (75), Expect = 0.11
Identities = 30/154 (19%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 24 QLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDK 83
Q+ + +K ++++ L + SSK + + + I++EL K+ + E+LE +
Sbjct: 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL 634
Query: 84 KMLEEEILNLKTHMENNMVELSKLQEYKSETDE------RAIQAVEKLEEIHLQMEA--- 134
LE+E L+ + N + K++ + E E + + ++ + + Q+E+
Sbjct: 635 HHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEK 694
Query: 135 --DCVEQIIRETKRTVAVLDTCSHLLSSLESTGK 166
+++ E +R V L S ++ L+ K
Sbjct: 695 ENSQLDEENLELRRNVESLKCASMKMAQLQLENK 728
Score = 33.1 bits (74), Expect = 0.14
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 14/120 (11%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECE 77
E L+TD + L+ K + L E +K + QQ ++ K+ +CE
Sbjct: 1262 EVLQTDHKNLKSLLNNSKLEQTRLEAE----------FSKLKEQYQQLDITSTKLNNQCE 1311
Query: 78 KLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDE----RAIQAVEKLEEIHLQME 133
L + K LEEE +L ++ M++ L E E+ + Q ++KL E+ Q E
Sbjct: 1312 LLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKE 1371
Score = 32.3 bits (72), Expect = 0.24
Identities = 19/81 (23%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Query: 11 NEDFVCHEDLKTDQLKMDILIKKLKQKFD-DLTPEEEAVSSKCVNLAKD---NQVIQQEL 66
N++ + H++ TD + +L KL+ L +EE +++ L + NQ ++QEL
Sbjct: 938 NKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 997
Query: 67 LSMKKVQQECEKLEEDKKMLE 87
++KK + ++ +++++M++
Sbjct: 998 KTVKKNYEALKQRQDEERMVQ 1018
Score = 30.0 bits (66), Expect = 1.2
Identities = 29/135 (21%), Positives = 64/135 (47%), Gaps = 13/135 (9%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQ--- 74
E L+ + ++D +L++ + L + S K L +N+ ++ E +KK +
Sbjct: 690 ESLEKENSQLDEENLELRRNVESL----KCASMKMAQLQLENKELESEKEQLKKGLELLK 745
Query: 75 ----ECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHL 130
+ E+LE + L+ E L+ +EN+ ++ +L+ + + + LEE L
Sbjct: 746 ASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEE--L 803
Query: 131 QMEADCVEQIIRETK 145
++ + +EQ+ +E K
Sbjct: 804 KISSKRLEQLEKENK 818
Score = 29.3 bits (64), Expect = 2.0
Identities = 25/109 (22%), Positives = 53/109 (48%), Gaps = 7/109 (6%)
Query: 60 QVIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMV---ELSKLQEYKSETDE 116
Q ++++ + +QE E++E + K L++E +NL + + + EL L+E D+
Sbjct: 265 QELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDK 324
Query: 117 RAIQAVEKLEEIH-LQMEADCVEQIIRETKRTVAVLDTCSHLLSSLEST 164
+ E +H ++ VE++ + + +L+T + L LE T
Sbjct: 325 LESEVSRYKERLHDIEFYKARVEELKEDNQ---VLLETKTMLEDQLEGT 370
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 47.0 bits (110), Expect = 9e-06
Identities = 35/157 (22%), Positives = 76/157 (48%), Gaps = 17/157 (10%)
Query: 12 EDFVCHEDLKTDQLKMDIL------IKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQE 65
E+ + HE +K K+ + IKK + + + E + ++ +L K+N+++Q++
Sbjct: 588 ENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKK 647
Query: 66 LLSMKKVQQECEKLEEDKKMLEEEILNLKTHME---NNMVELSKLQEYKSETDERAIQAV 122
+ ++K ++ E LE++ LE E LK ++ N +L L++ S+ DE ++
Sbjct: 648 ITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELR 707
Query: 123 EKLEEI--------HLQMEADCVEQIIRETKRTVAVL 151
+E + LQ+E +E + K+ + +L
Sbjct: 708 RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELL 744
Score = 41.6 bits (96), Expect = 4e-04
Identities = 29/113 (25%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECE 77
E L+ +DI ++L++ ++ + + + S+ +L +NQ +Q+ L +K + E
Sbjct: 752 ERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLE 811
Query: 78 KLEEDKKMLEEEILNL---KTHMENNMVELSKLQEYKSETDERAIQAVEKLEE 127
+LE++ K LE+E L K +E L + E K T E + LE+
Sbjct: 812 QLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEK 864
Score = 35.4 bits (80), Expect = 0.028
Identities = 39/146 (26%), Positives = 71/146 (48%), Gaps = 16/146 (10%)
Query: 26 KMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDK-K 84
K++ + + K++ D+ E ++ L +DNQV+ E +M + Q E + DK
Sbjct: 324 KLESEVSRYKERLHDI----EFYKARVEELKEDNQVL-LETKTMLEDQLEGTRARSDKLH 378
Query: 85 MLEEEILNLKT-----HMENNMVELSKLQEYKSETDERAIQAVEKLEE-IHLQMEADCVE 138
LE+E L LK ME +M + K++E E + + ++E +HL E +E
Sbjct: 379 ELEKENLQLKAKLHDMEMERDM-DRKKIEELMEENMTLEMAQKQSMDESLHLGWE---LE 434
Query: 139 QIIRETKRTVAVLDTCSHLLSSLEST 164
QI R ++ + A + H ++ L S+
Sbjct: 435 QISRTSELSEAPQKSLGHEVNELTSS 460
Score = 35.4 bits (80), Expect = 0.028
Identities = 43/156 (27%), Positives = 78/156 (50%), Gaps = 20/156 (12%)
Query: 20 LKTDQLKMDILIKKLKQKFD--DLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECE 77
L+ D+ +++ K+L+Q+ + D T EE V K NL K+N+ + +E+ K+ +
Sbjct: 827 LEKDKKQLEKENKRLRQQAEIKDTTLEENNV--KIGNLEKENKTLSKEIGIYKESCVRLK 884
Query: 78 KLEEDKKMLEE----EILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
+LE++ K L + +I L T E+ + E K Q+ ++ + + +LE+I L
Sbjct: 885 ELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE----KLTHELEKIGLNK- 939
Query: 134 ADCVEQIIRETKRTVAVLDTCSHLLSSLESTGKPYL 169
E+++ + + T D L S LEST K L
Sbjct: 940 ----ERLLHDEQSTD---DRYKLLESKLESTLKKSL 968
Score = 33.5 bits (75), Expect = 0.11
Identities = 30/154 (19%), Positives = 69/154 (44%), Gaps = 11/154 (7%)
Query: 24 QLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDK 83
Q+ + +K ++++ L + SSK + + + I++EL K+ + E+LE +
Sbjct: 575 QISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL 634
Query: 84 KMLEEEILNLKTHMENNMVELSKLQEYKSETDE------RAIQAVEKLEEIHLQMEA--- 134
LE+E L+ + N + K++ + E E + + ++ + + Q+E+
Sbjct: 635 HHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEK 694
Query: 135 --DCVEQIIRETKRTVAVLDTCSHLLSSLESTGK 166
+++ E +R V L S ++ L+ K
Sbjct: 695 ENSQLDEENLELRRNVESLKCASMKMAQLQLENK 728
Score = 33.1 bits (74), Expect = 0.14
Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 14/120 (11%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECE 77
E L+TD + L+ K + L E +K + QQ ++ K+ +CE
Sbjct: 1261 EVLQTDHKNLKSLLNNSKLEQTRLEAE----------FSKLKEQYQQLDITSTKLNNQCE 1310
Query: 78 KLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDE----RAIQAVEKLEEIHLQME 133
L + K LEEE +L ++ M++ L E E+ + Q ++KL E+ Q E
Sbjct: 1311 LLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKE 1370
Score = 30.0 bits (66), Expect = 1.2
Identities = 29/135 (21%), Positives = 64/135 (47%), Gaps = 13/135 (9%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQ--- 74
E L+ + ++D +L++ + L + S K L +N+ ++ E +KK +
Sbjct: 690 ESLEKENSQLDEENLELRRNVESL----KCASMKMAQLQLENKELESEKEQLKKGLELLK 745
Query: 75 ----ECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHL 130
+ E+LE + L+ E L+ +EN+ ++ +L+ + + + LEE L
Sbjct: 746 ASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEE--L 803
Query: 131 QMEADCVEQIIRETK 145
++ + +EQ+ +E K
Sbjct: 804 KISSKRLEQLEKENK 818
Score = 29.3 bits (64), Expect = 2.0
Identities = 25/109 (22%), Positives = 53/109 (48%), Gaps = 7/109 (6%)
Query: 60 QVIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMV---ELSKLQEYKSETDE 116
Q ++++ + +QE E++E + K L++E +NL + + + EL L+E D+
Sbjct: 265 QELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDK 324
Query: 117 RAIQAVEKLEEIH-LQMEADCVEQIIRETKRTVAVLDTCSHLLSSLEST 164
+ E +H ++ VE++ + + +L+T + L LE T
Sbjct: 325 LESEVSRYKERLHDIEFYKARVEELKEDNQ---VLLETKTMLEDQLEGT 370
Score = 28.5 bits (62), Expect = 3.4
Identities = 19/81 (23%), Positives = 46/81 (56%), Gaps = 5/81 (6%)
Query: 11 NEDFVCHEDLKTDQLKMDILIKKLKQKFD-DLTPEEEAVSSKCVNLAKD---NQVIQQEL 66
N++ + H++ TD + +L KL+ L +EE +++ L + NQ ++QEL
Sbjct: 938 NKERLLHDEQSTDD-RYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 996
Query: 67 LSMKKVQQECEKLEEDKKMLE 87
++KK + ++ +++++M++
Sbjct: 997 KTVKKNYEALKQRQDEERMVQ 1017
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 46.2 bits (108), Expect = 2e-05
Identities = 42/162 (25%), Positives = 77/162 (47%), Gaps = 22/162 (13%)
Query: 3 INMLNVFGNEDFVCHEDLKTD----QLKMDILIKKL-KQKFDDLTPEEEAVSSKCVNLAK 57
+N + N+ F ++LK Q K+D + L +QK + +T +EE + NL K
Sbjct: 1155 LNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEK 1214
Query: 58 DNQ--VIQQELLSMKKVQQ-ECEKLEE----------DKKMLEEEILNLKTHMENNMVEL 104
D Q V QE + +Q+ CEK E +++++E+E+L H+EN + +
Sbjct: 1215 DRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKS 1274
Query: 105 SKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRETKR 146
+ + ++ + EKL+E +A +EQ+ + KR
Sbjct: 1275 PAIDSTRGDSSSLVAELQEKLQE----EKAKFLEQLEEQEKR 1312
Score = 31.2 bits (69), Expect = 0.53
Identities = 28/119 (23%), Positives = 64/119 (53%), Gaps = 17/119 (14%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKL 79
LK + + ++ +++ +F + E+EAV C+ KD ++++ E + M E ++L
Sbjct: 895 LKGELVCLEEVLQNKDNEFALVKHEKEAVI--CLQNEKDQKLLEMENI-MHSQNCEIKEL 951
Query: 80 EEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVE 138
++ ++++ E++ L H+EN+ KLQ ++E ++ LE+ HL+ D ++
Sbjct: 952 KQSREIVLEDLKKL--HVEND----EKLQLLRAE--------LQSLEQSHLKELEDTLQ 996
Score = 31.2 bits (69), Expect = 0.53
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 16/162 (9%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAK-DNQVIQQELLSMKKVQQE--- 75
LK +L+ +++ K+L +K L E + S ++ + D+ + EL +K+Q+E
Sbjct: 1246 LKEFKLEREVVEKELLEKVKHL--ENQIAKSPAIDSTRGDSSSLVAEL--QEKLQEEKAK 1301
Query: 76 -CEKLEEDKKMLEEEILNLKTHM--ENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQM 132
E+LEE +K EE+ N++T + E + L K + +KL+ Q
Sbjct: 1302 FLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQ 1361
Query: 133 E--ADCVEQIIRETKRTVAVLDTCSHLLSSLESTG---KPYL 169
E D +E + + R + +S L S+ PY+
Sbjct: 1362 ERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYV 1403
Score = 30.4 bits (67), Expect = 0.91
Identities = 29/152 (19%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLTPEEEA----VSSKCVNLAKDNQVIQQELLSMKKVQ 73
E+LK + + +I ++++ ++ E+E + K +L+ ++ EL +
Sbjct: 1015 EELKKENQQ---IINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAET 1071
Query: 74 QECEKLEEDKKMLEEEILN--LKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQ 131
E + L E+ + ++E L L+ EN E+SKL + + +E + +L +
Sbjct: 1072 DEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTI 1131
Query: 132 MEADCVEQIIRETKRTVAVLDTCSHLLSSLES 163
+ C+ ++I + +L + ++SL +
Sbjct: 1132 EKDQCISELISRHEEESNILKAELNKVTSLHN 1163
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 46.2 bits (108), Expect = 2e-05
Identities = 42/162 (25%), Positives = 77/162 (47%), Gaps = 22/162 (13%)
Query: 3 INMLNVFGNEDFVCHEDLKTD----QLKMDILIKKL-KQKFDDLTPEEEAVSSKCVNLAK 57
+N + N+ F ++LK Q K+D + L +QK + +T +EE + NL K
Sbjct: 1155 LNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELSALERQKDEKITQQEEKYEAIIQNLEK 1214
Query: 58 DNQ--VIQQELLSMKKVQQ-ECEKLEE----------DKKMLEEEILNLKTHMENNMVEL 104
D Q V QE + +Q+ CEK E +++++E+E+L H+EN + +
Sbjct: 1215 DRQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKS 1274
Query: 105 SKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRETKR 146
+ + ++ + EKL+E +A +EQ+ + KR
Sbjct: 1275 PAIDSTRGDSSSLVAELQEKLQE----EKAKFLEQLEEQEKR 1312
Score = 31.2 bits (69), Expect = 0.53
Identities = 28/119 (23%), Positives = 64/119 (53%), Gaps = 17/119 (14%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKL 79
LK + + ++ +++ +F + E+EAV C+ KD ++++ E + M E ++L
Sbjct: 895 LKGELVCLEEVLQNKDNEFALVKHEKEAVI--CLQNEKDQKLLEMENI-MHSQNCEIKEL 951
Query: 80 EEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVE 138
++ ++++ E++ L H+EN+ KLQ ++E ++ LE+ HL+ D ++
Sbjct: 952 KQSREIVLEDLKKL--HVEND----EKLQLLRAE--------LQSLEQSHLKELEDTLQ 996
Score = 31.2 bits (69), Expect = 0.53
Identities = 39/162 (24%), Positives = 72/162 (44%), Gaps = 16/162 (9%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAK-DNQVIQQELLSMKKVQQE--- 75
LK +L+ +++ K+L +K L E + S ++ + D+ + EL +K+Q+E
Sbjct: 1246 LKEFKLEREVVEKELLEKVKHL--ENQIAKSPAIDSTRGDSSSLVAEL--QEKLQEEKAK 1301
Query: 76 -CEKLEEDKKMLEEEILNLKTHM--ENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQM 132
E+LEE +K EE+ N++T + E + L K + +KL+ Q
Sbjct: 1302 FLEQLEEQEKRKNEEMQNVRTSLIAEQQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQ 1361
Query: 133 E--ADCVEQIIRETKRTVAVLDTCSHLLSSLESTG---KPYL 169
E D +E + + R + +S L S+ PY+
Sbjct: 1362 ERDKDLIESLSEDRARLLEEKKKLEEEVSKLRSSSFVPSPYV 1403
Score = 30.4 bits (67), Expect = 0.91
Identities = 29/152 (19%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLTPEEEA----VSSKCVNLAKDNQVIQQELLSMKKVQ 73
E+LK + + +I ++++ ++ E+E + K +L+ ++ EL +
Sbjct: 1015 EELKKENQQ---IINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAET 1071
Query: 74 QECEKLEEDKKMLEEEILN--LKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQ 131
E + L E+ + ++E L L+ EN E+SKL + + +E + +L +
Sbjct: 1072 DEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTI 1131
Query: 132 MEADCVEQIIRETKRTVAVLDTCSHLLSSLES 163
+ C+ ++I + +L + ++SL +
Sbjct: 1132 EKDQCISELISRHEEESNILKAELNKVTSLHN 1163
>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
Length = 446
Score = 46.2 bits (108), Expect = 2e-05
Identities = 33/140 (23%), Positives = 70/140 (50%), Gaps = 8/140 (5%)
Query: 31 IKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEI 90
+++++Q +L E + + C++L K N +Q EL +K Q+E E L+ K LE ++
Sbjct: 142 VEEIEQHNKELCKENQELKDSCISLQKQNSDMQAEL---QKKQEELETLQSINKKLELKV 198
Query: 91 LNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIR----ETKR 146
K + E +++L + + S +E+ V++L + L + +E++++ +T++
Sbjct: 199 KEQKDYWETELLQLKEQNQKMSSENEKMGIRVDQL-QAQLSTQEKEMEKLVQGDQDKTEQ 257
Query: 147 TVAVLDTCSHLLSSLESTGK 166
+ HL SL K
Sbjct: 258 LEQLKKENDHLFLSLTEQRK 277
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 45.4 bits (106), Expect = 3e-05
Identities = 31/133 (23%), Positives = 66/133 (49%), Gaps = 6/133 (4%)
Query: 18 EDLKTDQLKMDILIK---KLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQ 74
+DL+ ++ K++ L K KL+Q+ DDL E C++L + + ++ +L K Q+
Sbjct: 1012 DDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDL---KLAQE 1068
Query: 75 ECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEA 134
E DK+ L E++ + M N ++ Q + ++ + ++EE+ ++EA
Sbjct: 1069 STMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEA 1128
Query: 135 DCVEQIIRETKRT 147
+ + E +R+
Sbjct: 1129 ERASRAKAEKQRS 1141
Score = 43.5 bits (101), Expect = 1e-04
Identities = 30/118 (25%), Positives = 50/118 (42%), Gaps = 9/118 (7%)
Query: 32 KKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQE----LLSMKKVQQECEKLEEDKKMLE 87
KKL Q+ D EAV+SKC +L K Q +Q E ++ +++ C L++ ++ +
Sbjct: 1395 KKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRNFD 1454
Query: 88 EEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRETK 145
+ + K E EL Q+ + EE D +E + RE K
Sbjct: 1455 KVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEE-----SLDHLETLKRENK 1507
Score = 40.0 bits (92), Expect = 0.001
Identities = 28/118 (23%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQEC--- 76
L Q D ++ + KQK+++ E EA K+++ + EL +K +E
Sbjct: 1446 LDKKQRNFDKVLAEWKQKYEETQAELEASQ-------KESRSLSTELFKVKNAYEESLDH 1498
Query: 77 -EKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
E L+ + K L++EI +L + + +L++ K + D + LEE +E
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLE 1556
Score = 39.3 bits (90), Expect = 0.002
Identities = 42/184 (22%), Positives = 82/184 (44%), Gaps = 23/184 (12%)
Query: 16 CHEDLKTDQLKMDILIKKLKQKFDD-------LTPEEEAVSSKCVNLAKDNQVIQQELLS 68
C + +KT +++++ IK++ ++ +D LT ++ + +C L KD ++ L+
Sbjct: 909 CDQLIKT-KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 964
Query: 69 MKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSET------DERAIQAV 122
+ KV++E E K L EE+ L + E LQE +T +E + +
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024
Query: 123 EKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLS-----SLESTGKPYLTKRIFNHK 177
K + L+ + D +E + + K+ L+ L + EST K+ N K
Sbjct: 1025 TK-AKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEK 1083
Query: 178 VLRK 181
+ +K
Sbjct: 1084 LKKK 1087
Score = 34.3 bits (77), Expect = 0.063
Identities = 13/49 (26%), Positives = 30/49 (61%)
Query: 87 EEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEAD 135
E+E+ N+K E EL+K + + E +E+ + +++ ++ LQ++A+
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
Score = 34.3 bits (77), Expect = 0.063
Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 14/113 (12%)
Query: 35 KQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQEC-------EKLEEDKKMLE 87
+Q DDL EE+ V++ K Q + S+++ ++ C KLE D K+ +
Sbjct: 1008 QQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQ 1067
Query: 88 EEILN-------LKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
E ++ L ++ E+S LQ + AIQ +K++E+ ++E
Sbjct: 1068 ESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIE 1120
Score = 31.2 bits (69), Expect = 0.53
Identities = 24/110 (21%), Positives = 55/110 (50%), Gaps = 10/110 (9%)
Query: 63 QQELLSMK----KVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERA 118
++E+ +MK K ++E K E +K LEE+++ L + +++ + ++ +ER
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERC 909
Query: 119 IQAVEKLEEIHLQME-----ADCVEQIIRE-TKRTVAVLDTCSHLLSSLE 162
Q ++ ++ +++ A+ E+I E T + + D CS L ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959
Score = 30.4 bits (67), Expect = 0.91
Identities = 29/129 (22%), Positives = 65/129 (50%), Gaps = 13/129 (10%)
Query: 26 KMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQV-IQQELLSMKKVQQECEKLEEDKK 84
K + +K+++ ++ T + EA ++ D+ + +++ S+++V+Q KLE++K
Sbjct: 1170 KREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQIDSLQRVKQ---KLEKEKS 1226
Query: 85 MLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRET 144
L+ EI +L ++ME + + K+ ++ ++L EI + E +++I E
Sbjct: 1227 ELKMEINDLASNMET-------VSKAKANFEKMCRTLEDQLSEIKTKEEEQ--QRLINEL 1277
Query: 145 KRTVAVLDT 153
A L T
Sbjct: 1278 SAQKARLHT 1286
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 45.1 bits (105), Expect = 4e-05
Identities = 27/100 (27%), Positives = 56/100 (56%), Gaps = 3/100 (3%)
Query: 11 NEDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMK 70
NE + H +++ D L+ K L+++ +L +E V+S+ VNL+ N+ + QEL +
Sbjct: 266 NEKLIAHLNIQVDFLQQ--ANKDLEKRIRELMETKETVTSEVVNLSNKNEKLCQELTEID 323
Query: 71 KVQQECEK-LEEDKKMLEEEILNLKTHMENNMVELSKLQE 109
++ Q+ E+ EE + ++E+ K ++ + E+ L+E
Sbjct: 324 QLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQDLEE 363
Score = 32.0 bits (71), Expect = 0.31
Identities = 24/114 (21%), Positives = 54/114 (47%), Gaps = 3/114 (2%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKL 79
LK + D I L+++ D E + V K+N+ +Q +L +M + QE L
Sbjct: 781 LKETLVNRDREINSLRRQLDAAHKELDEVGRSREIAFKENRRLQDDLATMARENQEI-SL 839
Query: 80 EEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
E + + E+E +K+ + + E+S+ + + ++ +++ + +H + E
Sbjct: 840 ELEAAVQEKE--EMKSRVHKYITEVSRWESLMAAKEKENQDLLDRFQMLHNRAE 891
Score = 30.8 bits (68), Expect = 0.69
Identities = 29/135 (21%), Positives = 62/135 (45%), Gaps = 10/135 (7%)
Query: 26 KMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQV---IQQELLSMKKVQQECEKLEED 82
K I ++ + + D+ P E VSS V D + +Q ++++QQE +L+E
Sbjct: 161 KRSIAFRRQRMQIDEPVPPSE-VSSYPVPQPDDPYIADLLQVADNRIQELQQEVHQLQEK 219
Query: 83 KKMLEEEILNLKTHMENNMVELSKLQ---EYKSETDERAIQAVEKLEE---IHLQMEADC 136
M+E + + +E E+ +L + D ++++ K E HL ++ D
Sbjct: 220 LAMMESGVRDYSKQIELREREIERLSVALDGGRSPDVLSLESRNKTNEKLIAHLNIQVDF 279
Query: 137 VEQIIRETKRTVAVL 151
++Q ++ ++ + L
Sbjct: 280 LQQANKDLEKRIREL 294
Score = 29.6 bits (65), Expect = 1.5
Identities = 24/128 (18%), Positives = 59/128 (46%), Gaps = 20/128 (15%)
Query: 1 MTINMLNVFGNEDFVCHEDLKTDQL-------KMDILI----------KKLKQKFDDLTP 43
+T ++N+ + +C E + DQL K ++L K++K+K ++
Sbjct: 301 VTSEVVNLSNKNEKLCQELTEIDQLAQQLERHKEEVLETADKELGEAKKEIKRKLSEMQD 360
Query: 44 EEEAVSSKCVNL---AKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEILNLKTHMENN 100
EE ++ + L K+ + + ELL ++ +LE++K+ L +++ +
Sbjct: 361 LEETMAKLQLELNLCQKEKERLSDELLVKSDLETVVHQLEQEKQRLSKKVESFAVTERQL 420
Query: 101 MVELSKLQ 108
+E+ +++
Sbjct: 421 TLEVERMR 428
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 43.9 bits (102), Expect = 8e-05
Identities = 30/133 (22%), Positives = 70/133 (52%), Gaps = 6/133 (4%)
Query: 18 EDLKTDQLKMDILIK---KLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQ 74
+DL+ ++ K++IL K KL+Q+ DDL E ++L + + ++ +L K Q+
Sbjct: 1011 DDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDL---KLAQE 1067
Query: 75 ECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEA 134
+E DK+ L+E++ + + N + ++ Q + + ++ + ++EE+ ++EA
Sbjct: 1068 STMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEA 1127
Query: 135 DCVEQIIRETKRT 147
+ + E +R+
Sbjct: 1128 ERASRAKAEKQRS 1140
Score = 42.4 bits (98), Expect = 2e-04
Identities = 36/158 (22%), Positives = 62/158 (39%), Gaps = 12/158 (7%)
Query: 32 KKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQE----LLSMKKVQQECEKLEEDKKMLE 87
KKL Q+ + EAV++KC +L K Q +Q E +L +++ C L++ ++ +
Sbjct: 1394 KKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFD 1453
Query: 88 EEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRETKRT 147
+ + K E EL Q+ + EE D +E + RE K
Sbjct: 1454 KVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEE-----SLDQLETLRRENKN- 1507
Query: 148 VAVLDTCSHLLSSLESTGKPYLTKRIFNHKVLRKNCMI 185
+ S L + GK +V ++ C I
Sbjct: 1508 --LQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEI 1543
Score = 42.0 bits (97), Expect = 3e-04
Identities = 28/118 (23%), Positives = 55/118 (46%), Gaps = 11/118 (9%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQEC--- 76
L Q D ++ + KQK+++ E EA K+++ + EL +K V +E
Sbjct: 1445 LDKKQRNFDKVLSEWKQKYEETQAELEASQ-------KESRSLSTELFKVKNVYEESLDQ 1497
Query: 77 -EKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
E L + K L++EI +L + ++ +L++ K + ++ + LEE +E
Sbjct: 1498 LETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLE 1555
Score = 36.6 bits (83), Expect = 0.013
Identities = 26/118 (22%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECE 77
++L+ + K++ +LK + DDL+ EA+S NL K + ++ ++ +K ++E +
Sbjct: 1211 DNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQ 1270
Query: 78 KLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEAD 135
+L D L + L+T +L + S+ + +++EE+ Q+E +
Sbjct: 1271 RLIND---LTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEE 1325
Score = 35.8 bits (81), Expect = 0.022
Identities = 30/145 (20%), Positives = 70/145 (48%), Gaps = 23/145 (15%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDD-------LTPEEEAVSSKCVNLAKDNQVIQQELLSMK 70
E L ++++++ IK++ ++ ++ LT ++ + +C L KD ++ L++
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLA 965
Query: 71 KVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEE--- 127
KV++E E K L EE+ L + + +LSK ++ ET ++ + ++ E+
Sbjct: 966 KVEKEKHATENKVKNLTEEMAGL----DETIAKLSKEKKALQETHQQTLDDLQAEEDKVN 1021
Query: 128 ------IHLQMEADCVEQIIRETKR 146
L+ + D +E + + K+
Sbjct: 1022 ILTKAKTKLEQQVDDLEGSLEQEKK 1046
Score = 33.1 bits (74), Expect = 0.14
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 11/106 (10%)
Query: 35 KQKFDDLTPEEEAV---SSKCVNLAKDNQVIQQELLSMKKVQQECE----KLEEDKKMLE 87
+Q DDL EE+ V + L + ++ L KK++ + E KLE D K+ +
Sbjct: 1007 QQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1066
Query: 88 EEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
E ++ MEN+ +L + E K I +E + + +Q++
Sbjct: 1067 ESTMD----MENDKQQLDEKLEKKEFEISNLISKIEDEQAVEIQLQ 1108
Score = 30.4 bits (67), Expect = 0.91
Identities = 27/112 (24%), Positives = 54/112 (48%), Gaps = 14/112 (12%)
Query: 63 QQELLSMK----KVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERA 118
++E+ +MK K + E K E +K LEE+++ L + +++ + ++ +ER
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERC 908
Query: 119 -------IQAVEKLEEIHLQMEADCVEQIIRE-TKRTVAVLDTCSHLLSSLE 162
IQ K++E+ + E + E+I E T + + D CS L ++
Sbjct: 909 EQLIKNKIQLEAKIKEVTERAEEE--EEINAELTAKKRKLEDECSELKKDID 958
Score = 28.9 bits (63), Expect = 2.6
Identities = 24/121 (19%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
Query: 26 KMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKM 85
K++ + +L+ + +++ E K D ++ +EL KK Q LE KK
Sbjct: 1732 KLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEEL---KKEQDTSAHLERMKKN 1788
Query: 86 LEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRETK 145
LE+ + +L+ ++ K + + + E ++ +E E + A+ V+ + + +
Sbjct: 1789 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKHER 1848
Query: 146 R 146
R
Sbjct: 1849 R 1849
Score = 27.7 bits (60), Expect = 5.9
Identities = 17/99 (17%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 30 LIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEE 89
++K+ + DD +E + + + + ++Q E+ +++ E+ E +K+ E+E
Sbjct: 1652 ILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEI---EELWATLEQTERSRKIAEQE 1708
Query: 90 ILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEI 128
+L+ ++ + + L K + + Q ++EE+
Sbjct: 1709 LLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEV 1747
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 43.5 bits (101), Expect = 1e-04
Identities = 37/131 (28%), Positives = 63/131 (48%), Gaps = 17/131 (12%)
Query: 32 KKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQE----LLSMKKVQQECEKLEEDKKMLE 87
KKL Q+ D + EAV++KC +L K Q +Q E ++ +++ L++ ++ +
Sbjct: 1392 KKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFD 1451
Query: 88 EEILNLKTHMENNMVEL-SKLQEYKS---------ETDERAIQAVE--KLEEIHLQME-A 134
+ + KT E + EL + L+E +S E A+ +E K E +L+ E A
Sbjct: 1452 KVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIA 1511
Query: 135 DCVEQIIRETK 145
D EQI K
Sbjct: 1512 DLTEQIAENGK 1522
Score = 36.2 bits (82), Expect = 0.017
Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 14/113 (12%)
Query: 35 KQKFDDLTPEEEAVSSKCVNLAK-DNQV--IQQELLSMKKVQQECE----KLEEDKKMLE 87
+Q DDL EE+ V+S +K + QV ++ L KK++ + E KLE D K+ +
Sbjct: 1005 QQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 1064
Query: 88 EEILNLKT-------HMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
E IL+L+ ++ E +LQ + +Q +K++E+ ++E
Sbjct: 1065 ESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIE 1117
Score = 32.7 bits (73), Expect = 0.18
Identities = 31/128 (24%), Positives = 58/128 (45%), Gaps = 13/128 (10%)
Query: 18 EDLKTDQLKMDILIKKLKQK---FDDLTPE-----EEAVSSKCVNLAKDNQVIQQELLSM 69
EDL D + + L L +K FD + E EE+ + +L K+++ + EL +
Sbjct: 1427 EDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASL-KESRSLSTELFKL 1485
Query: 70 KKVQQEC----EKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKL 125
K +E E ++ + K LE+EI +L + N + +L++ + + + L
Sbjct: 1486 KNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLAL 1545
Query: 126 EEIHLQME 133
EE +E
Sbjct: 1546 EEAEAALE 1553
Score = 32.0 bits (71), Expect = 0.31
Identities = 30/144 (20%), Positives = 66/144 (45%), Gaps = 18/144 (12%)
Query: 16 CHEDLKTDQLKMDILIKKLKQKFDD-------LTPEEEAVSSKCVNLAKDNQVIQQELLS 68
C + +K + +++ IK++ ++ +D LT ++ + +C L KD ++ L+
Sbjct: 906 CDQLIKA-KFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 961
Query: 69 MKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKS------ETDERAIQAV 122
+ KV++E E K L EE+ L + E LQE + +E + ++
Sbjct: 962 LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSL 1021
Query: 123 EKLEEIHLQMEADCVEQIIRETKR 146
K + L+ + + +E + + K+
Sbjct: 1022 NKTKS-KLEQQVEDLESSLEQEKK 1044
Score = 30.4 bits (67), Expect = 0.91
Identities = 25/110 (22%), Positives = 53/110 (48%), Gaps = 10/110 (9%)
Query: 63 QQELLSMK----KVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERA 118
++E+ +MK K + E K E +K LEE+++ L + +++ E + +ER
Sbjct: 847 EKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERC 906
Query: 119 IQAVEKLEEIHLQME-----ADCVEQIIRE-TKRTVAVLDTCSHLLSSLE 162
Q ++ ++ +++ A+ E+I E T + + D CS L ++
Sbjct: 907 DQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 956
Score = 29.6 bits (65), Expect = 1.5
Identities = 23/97 (23%), Positives = 53/97 (54%), Gaps = 4/97 (4%)
Query: 33 KLKQKFDDLTPEEEAVSSKCVNLAKDNQV-IQQELLSMKKVQQECEKLEEDKKMLEEEIL 91
KL++ ++ T + EA+ + D+ + +++ ++++V+Q KLE++K + EI
Sbjct: 1174 KLRRDLEEATLQHEAMVAALRKKHADSVAELGEQIDNLQRVKQ---KLEKEKSEFKLEID 1230
Query: 92 NLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEI 128
+L + ME+ + L++ +++ +A K EEI
Sbjct: 1231 DLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEI 1267
Score = 29.6 bits (65), Expect = 1.5
Identities = 28/120 (23%), Positives = 52/120 (43%), Gaps = 14/120 (11%)
Query: 19 DLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELL----------- 67
DL+ L+ + ++ L++K D E + + NL + Q +++E
Sbjct: 1178 DLEEATLQHEAMVAALRKKHADSVAE---LGEQIDNLQRVKQKLEKEKSEFKLEIDDLSS 1234
Query: 68 SMKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEE 127
SM+ V + LE+ + LE+++ + E LS+L KS A + +LEE
Sbjct: 1235 SMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEE 1294
Score = 29.6 bits (65), Expect = 1.5
Identities = 23/111 (20%), Positives = 52/111 (46%), Gaps = 11/111 (9%)
Query: 26 KMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKM 85
K++ + +L+ + +D + + K D ++ +EL KK Q LE KK
Sbjct: 1730 KLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMAEEL---KKEQDTSAHLERMKKN 1786
Query: 86 LEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVE-KLEEIHLQMEAD 135
LE+ + +L+ L + ++ + ++ IQ +E ++ E+ ++E +
Sbjct: 1787 LEQTVKDLQH-------RLDEAEQLALKGGKKQIQKLETRIRELEFELEGE 1830
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/132 (26%), Positives = 58/132 (43%), Gaps = 17/132 (12%)
Query: 32 KKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQE----LLSMKKVQQECEKLEEDKKMLE 87
KKL Q+ D EAV++KC +L K Q +Q E ++ +++ C L++ ++ +
Sbjct: 1395 KKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFD 1454
Query: 88 EEILNLKTHMENNMVELSKLQEYKSETD----------ERAIQAVE--KLEEIHLQME-A 134
+ + K E EL Q+ E ++ +E K E +LQ E +
Sbjct: 1455 KILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEIS 1514
Query: 135 DCVEQIIRETKR 146
D EQI KR
Sbjct: 1515 DLTEQIAEGGKR 1526
Score = 40.8 bits (94), Expect = 7e-04
Identities = 29/133 (21%), Positives = 66/133 (49%), Gaps = 6/133 (4%)
Query: 18 EDLKTDQLKMDILIK---KLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQ 74
+DL+ ++ K++ L K KL+Q+ DDL E ++L + + ++ +L K Q+
Sbjct: 1012 DDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDL---KLAQE 1068
Query: 75 ECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEA 134
+E DK+ L+E++ + M ++ Q + ++ + ++EE+ ++EA
Sbjct: 1069 STMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEA 1128
Query: 135 DCVEQIIRETKRT 147
+ + E +R+
Sbjct: 1129 ERASRAKAEKQRS 1141
Score = 38.5 bits (88), Expect = 0.003
Identities = 34/144 (23%), Positives = 69/144 (47%), Gaps = 18/144 (12%)
Query: 16 CHEDLKTDQLKMDILIKKLKQKFDD-------LTPEEEAVSSKCVNLAKDNQVIQQELLS 68
C + +KT +++++ IK++ ++ +D LT ++ + +C L KD ++ L+
Sbjct: 909 CDQLIKT-KIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE---LT 964
Query: 69 MKKVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSET------DERAIQAV 122
+ KV++E E K L EE+ L + E LQE +T +E + +
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024
Query: 123 EKLEEIHLQMEADCVEQIIRETKR 146
K +I L+ + D +E + + K+
Sbjct: 1025 TK-AKIKLEQQVDDLEGSLEQEKK 1047
Score = 37.4 bits (85), Expect = 0.007
Identities = 27/118 (22%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQEC--- 76
L Q D ++ + KQK ++ E EA K+++ + EL +K +E
Sbjct: 1446 LDKKQRNFDKILAEWKQKCEETHAELEASQ-------KESRSLSTELFKIKNAYEESLDQ 1498
Query: 77 -EKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
E L+ + K L++EI +L + + +L++ K + ++ + LEE +E
Sbjct: 1499 LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLE 1556
Score = 35.4 bits (80), Expect = 0.028
Identities = 25/102 (24%), Positives = 47/102 (46%), Gaps = 4/102 (3%)
Query: 33 KLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEILN 92
+ K + D + EE +K K Q +Q ++ V +C LE+ K+ L+ E+ +
Sbjct: 1376 RTKYETDAIQRTEELEEAK----KKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVED 1431
Query: 93 LKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEA 134
L +E + L + + D+ + +K EE H ++EA
Sbjct: 1432 LMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEA 1473
Score = 34.3 bits (77), Expect = 0.063
Identities = 13/49 (26%), Positives = 30/49 (61%)
Query: 87 EEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEAD 135
E+E+ N+K E EL+K + + E +E+ + +++ ++ LQ++A+
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAE 898
Score = 34.3 bits (77), Expect = 0.063
Identities = 26/113 (23%), Positives = 54/113 (47%), Gaps = 14/113 (12%)
Query: 35 KQKFDDLTPEEEAVSSKC---VNLAKDNQVIQQELLSMKKVQQECE----KLEEDKKMLE 87
+Q DDL EE+ V++ + L + ++ L KK++ + E KLE D K+ +
Sbjct: 1008 QQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQ 1067
Query: 88 EEILNLKT-------HMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
E ++++ ++ E+S LQ + +Q +K++E+ ++E
Sbjct: 1068 ESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIE 1120
Score = 31.2 bits (69), Expect = 0.53
Identities = 24/110 (21%), Positives = 55/110 (50%), Gaps = 10/110 (9%)
Query: 63 QQELLSMK----KVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERA 118
++E+ +MK K ++E K E +K LEE+++ L + +++ + ++ +ER
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERC 909
Query: 119 IQAVEKLEEIHLQME-----ADCVEQIIRE-TKRTVAVLDTCSHLLSSLE 162
Q ++ ++ +++ A+ E+I E T + + D CS L ++
Sbjct: 910 DQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDID 959
Score = 30.8 bits (68), Expect = 0.69
Identities = 34/152 (22%), Positives = 75/152 (49%), Gaps = 9/152 (5%)
Query: 26 KMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQV-IQQELLSMKKVQQECEKLEEDKK 84
K + +K+++ ++ T + EA ++ D+ + +++ ++++V+Q KLE++K
Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQ---KLEKEKS 1226
Query: 85 MLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIR-- 142
++ EI +L ++ME L++ +++ + ++ EE ++ D Q R
Sbjct: 1227 EMKMEIDDLASNMETVSKAKGNLEKMCRALEDQ-LSEIKTKEEEQQRLINDLTAQRARLQ 1285
Query: 143 -ETKRTVAVLDTCSHLLSSLESTGKPYLTKRI 173
E+ LD L+S L S GK T++I
Sbjct: 1286 TESGEYSRQLDEKDTLVSQL-SRGKQAFTQQI 1316
Score = 30.4 bits (67), Expect = 0.91
Identities = 33/154 (21%), Positives = 67/154 (43%), Gaps = 21/154 (13%)
Query: 26 KMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKM 85
K++ I +++ + +D+ E K D ++ +EL KK Q LE KK
Sbjct: 1733 KLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEEL---KKEQDTSAHLERMKKN 1789
Query: 86 LEEEILNLKTHME--------NNMVELSKLQ--------EYKSETDERAIQAVEKLEEIH 129
LE+ + +L+ ++ ++ KL+ E +SE +R ++AV+ L + H
Sbjct: 1790 LEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESE-QKRNVEAVKGLRK-H 1847
Query: 130 LQMEADCVEQIIRETKRTVAVLDTCSHLLSSLES 163
+ + Q + K + + D L + ++S
Sbjct: 1848 ERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKS 1881
Score = 27.7 bits (60), Expect = 5.9
Identities = 29/148 (19%), Positives = 66/148 (44%), Gaps = 16/148 (10%)
Query: 30 LIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEE 89
++K + DD +E + + + + ++Q E+ ++++ E+ E +K+ E+E
Sbjct: 1653 ILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEI---EELRATLEQTERSRKIAEQE 1709
Query: 90 ILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRETKRTVA 149
+L+ ++ + + L K + + Q ++E+I EA E+ ++ A
Sbjct: 1710 LLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDI--IQEARNAEEKAKKAITDAA 1767
Query: 150 VL--------DTCSHL---LSSLESTGK 166
++ DT +HL +LE T K
Sbjct: 1768 MMAEELKKEQDTSAHLERMKKNLEQTVK 1795
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 42.7 bits (99), Expect = 2e-04
Identities = 31/139 (22%), Positives = 58/139 (41%), Gaps = 12/139 (8%)
Query: 32 KKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQE----LLSMKKVQQECEKLEEDKKMLE 87
KKL Q+ + E +SKC +L K Q +Q E + +++ C L++ ++ +
Sbjct: 1395 KKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFD 1454
Query: 88 EEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEADCVEQIIRETKRT 147
+ + K ++ + EL Q+ + EE+ D +E + RE K
Sbjct: 1455 KVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEV-----VDQLETLRRENKN- 1508
Query: 148 VAVLDTCSHLLSSLESTGK 166
+ + S L + TGK
Sbjct: 1509 --LQEEISDLTEQIAETGK 1525
Score = 42.0 bits (97), Expect = 3e-04
Identities = 39/148 (26%), Positives = 72/148 (48%), Gaps = 14/148 (9%)
Query: 18 EDLKTDQLKMDILIK---KLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQ 74
+DL+ ++ K++ LIK KL+Q+ DDL E +L + + ++ +L K Q+
Sbjct: 1012 DDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDL---KMSQE 1068
Query: 75 ECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEA 134
LE DK+ +EE+ ++ ELS+LQ + ++Q +K++E+ ++E
Sbjct: 1069 SIMDLENDKQQIEEK-------LKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIE- 1120
Query: 135 DCVEQIIRETKRTVAVLDTCSHLLSSLE 162
+ E+I E + S L LE
Sbjct: 1121 ELEEEIEAEHTLRAKIEKQRSDLARELE 1148
Score = 37.4 bits (85), Expect = 0.007
Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 11/118 (9%)
Query: 20 LKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQEC--- 76
L Q D ++ + KQK D+ E EA K+++ + EL M+ +E
Sbjct: 1446 LDKKQRNFDKVLAEWKQKLDESQAELEAAQ-------KESRSLSTELFKMRNAYEEVVDQ 1498
Query: 77 -EKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQME 133
E L + K L+EEI +L + L + ++ K ++ LEE+ +E
Sbjct: 1499 LETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLE 1556
Score = 37.4 bits (85), Expect = 0.007
Identities = 24/119 (20%), Positives = 62/119 (52%), Gaps = 10/119 (8%)
Query: 33 KLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEE-------DKKM 85
K++ ++++ + E + + NL ++ + +++ K QE EK ++ D ++
Sbjct: 1487 KMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQV 1546
Query: 86 LEEEILNLKTHMENNMVELS-KLQEYKSETDERAIQAVEKLEEI--HLQMEADCVEQII 141
EE+ H E+ ++ + +L + KSE D + I+ E++E++ + Q A+ ++ ++
Sbjct: 1547 ALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVL 1605
Score = 37.0 bits (84), Expect = 0.010
Identities = 33/154 (21%), Positives = 70/154 (45%), Gaps = 17/154 (11%)
Query: 18 EDLKTDQLKMDILIKKLKQKFDD-------LTPEEEAVSSKCVNLAKDNQVIQQELLSMK 70
E L ++ ++ +K+L ++ ++ L ++ + KC +L +D ++ L++
Sbjct: 910 EGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLE---LTLT 966
Query: 71 KVQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSET------DERAIQAVEK 124
KV++E E K L EE+ L+ ++ E LQE +T +E + + K
Sbjct: 967 KVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIK 1026
Query: 125 LEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLL 158
+ L+ + D +E + + K+ A L+ L
Sbjct: 1027 I-NAKLEQQTDDLEGSLEQEKKLRADLERAKRKL 1059
Score = 32.3 bits (72), Expect = 0.24
Identities = 23/102 (22%), Positives = 48/102 (47%), Gaps = 4/102 (3%)
Query: 33 KLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQECEKLEEDKKMLEEEILN 92
+ K + D + EE +K K Q +Q+ + + +C LE+ K+ L+ E+ +
Sbjct: 1376 RTKYETDAIQRTEELEEAK----KKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVED 1431
Query: 93 LKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQMEA 134
L +E + + L + + D+ + +KL+E ++EA
Sbjct: 1432 LMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEA 1473
Score = 30.4 bits (67), Expect = 0.91
Identities = 24/121 (19%), Positives = 52/121 (42%), Gaps = 13/121 (10%)
Query: 12 EDFVCHEDLKTDQLKMDILIKKLKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKK 71
EDF E K + + + K+L++K L E+ + + +Q E ++
Sbjct: 858 EDF---ERTKEELARSEARRKELEEKMVSLLQEKNDLQLQ----------VQSETENLMD 904
Query: 72 VQQECEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDERAIQAVEKLEEIHLQ 131
++ CE L + K +LE ++ L +E S+L K +++ ++++ L
Sbjct: 905 AEERCEGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELT 964
Query: 132 M 132
+
Sbjct: 965 L 965
Score = 29.6 bits (65), Expect = 1.5
Identities = 40/167 (23%), Positives = 72/167 (43%), Gaps = 31/167 (18%)
Query: 18 EDLKTDQLKMDILIKK--LKQKFDDLTPEEEAVSSKCVNLAKDNQVIQQELLSMKKVQQE 75
+D + QL D+ ++K L+ + +L+ E S L K Q + Q+L +K+ +E
Sbjct: 1266 KDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEE 1325
Query: 76 ------------------CEKLEEDKKMLEEEILNLKTHMENNMVELSKLQEYKSETDER 117
C+ L E + +E L+ + E+++ + K ETD
Sbjct: 1326 ETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRT-KYETD-- 1382
Query: 118 AIQAVEKLEEIHLQMEADCVEQIIRETKRTVAVLDTCSHLLSSLEST 164
AIQ E+LEE ++ Q ++E + +T + +SLE T
Sbjct: 1383 AIQRTEELEEAKKKL-----AQRLQEAEENT---ETANSKCASLEKT 1421
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.348
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,265,558
Number of Sequences: 37866
Number of extensions: 268322
Number of successful extensions: 4976
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 276
Number of HSP's successfully gapped in prelim test: 504
Number of HSP's that attempted gapping in prelim test: 2634
Number of HSP's gapped (non-prelim): 2354
length of query: 185
length of database: 18,247,518
effective HSP length: 96
effective length of query: 89
effective length of database: 14,612,382
effective search space: 1300501998
effective search space used: 1300501998
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.