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Search of human proteins with 169215514
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|169215514 PREDICTED: hypothetical protein [Homo sapiens]
(357 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|169215514 PREDICTED: hypothetical protein [Homo sapiens] 691 0.0
gi|169215927 PREDICTED: hypothetical protein [Homo sapiens] 687 0.0
gi|239752137 PREDICTED: hypothetical protein [Homo sapiens] 687 0.0
gi|169215483 PREDICTED: hypothetical protein isoform 2 [Homo sap... 677 0.0
gi|194294521 intersectin 2 isoform 1 [Homo sapiens] 65 1e-10
gi|194294525 intersectin 2 isoform 2 [Homo sapiens] 65 1e-10
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 62 1e-09
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 62 1e-09
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 62 1e-09
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 62 1e-09
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 62 1e-09
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 62 1e-09
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 62 1e-09
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 62 1e-09
gi|194294523 intersectin 2 isoform 3 [Homo sapiens] 61 2e-09
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 60 4e-09
gi|42794779 myosin 18A isoform b [Homo sapiens] 59 5e-09
gi|28416946 myosin 18A isoform a [Homo sapiens] 59 5e-09
gi|21735548 centrosomal protein 2 [Homo sapiens] 59 9e-09
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 57 2e-08
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 57 2e-08
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 57 3e-08
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 56 4e-08
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 56 4e-08
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 56 4e-08
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 56 4e-08
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 56 6e-08
gi|238908495 similar to pleckstrin homology domain protein (5V32... 55 1e-07
gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens] 55 1e-07
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 55 1e-07
>gi|169215514 PREDICTED: hypothetical protein [Homo sapiens]
Length = 357
Score = 691 bits (1784), Expect = 0.0
Identities = 357/357 (100%), Positives = 357/357 (100%)
Query: 1 MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK 60
MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK
Sbjct: 1 MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK 60
Query: 61 DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR 120
DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR
Sbjct: 61 DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR 120
Query: 121 ERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV 180
ERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV
Sbjct: 121 ERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV 180
Query: 181 TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA 240
TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA
Sbjct: 181 TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA 240
Query: 241 EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL 300
EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL
Sbjct: 241 EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL 300
Query: 301 LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT 357
LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT
Sbjct: 301 LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT 357
>gi|169215927 PREDICTED: hypothetical protein [Homo sapiens]
Length = 357
Score = 687 bits (1774), Expect = 0.0
Identities = 356/357 (99%), Positives = 356/357 (99%)
Query: 1 MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK 60
MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK
Sbjct: 1 MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK 60
Query: 61 DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR 120
DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR
Sbjct: 61 DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR 120
Query: 121 ERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV 180
ERAERVRRRLEEAERHKE LEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV
Sbjct: 121 ERAERVRRRLEEAERHKEDLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV 180
Query: 181 TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA 240
TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA
Sbjct: 181 TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA 240
Query: 241 EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL 300
EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL
Sbjct: 241 EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL 300
Query: 301 LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT 357
LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT
Sbjct: 301 LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT 357
>gi|239752137 PREDICTED: hypothetical protein [Homo sapiens]
Length = 357
Score = 687 bits (1774), Expect = 0.0
Identities = 356/357 (99%), Positives = 356/357 (99%)
Query: 1 MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK 60
MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK
Sbjct: 1 MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK 60
Query: 61 DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR 120
DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR
Sbjct: 61 DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR 120
Query: 121 ERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV 180
ERAERVRRRLEEAERHKE LEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV
Sbjct: 121 ERAERVRRRLEEAERHKEDLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV 180
Query: 181 TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA 240
TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA
Sbjct: 181 TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA 240
Query: 241 EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL 300
EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL
Sbjct: 241 EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL 300
Query: 301 LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT 357
LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT
Sbjct: 301 LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT 357
>gi|169215483 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 356
Score = 677 bits (1748), Expect = 0.0
Identities = 354/357 (99%), Positives = 354/357 (99%), Gaps = 1/357 (0%)
Query: 1 MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK 60
MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK
Sbjct: 1 MCRATLGLPLPPIVIQPARRSLPPIVTPASRRLGPRGGRHLGSVSTAMAATQELLLQLQK 60
Query: 61 DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR 120
DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR
Sbjct: 61 DNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAAR 120
Query: 121 ERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLV 180
ERAERVRRRLEEAERHKE LEQHSRQLQEQWEELSSQLFY GGE QSQKSTEQQLAAQLV
Sbjct: 121 ERAERVRRRLEEAERHKEDLEQHSRQLQEQWEELSSQLFY-GGEPQSQKSTEQQLAAQLV 179
Query: 181 TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA 240
TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA
Sbjct: 180 TLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAA 239
Query: 241 EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL 300
EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL
Sbjct: 240 EELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRRCVLGALQVL 299
Query: 301 LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT 357
LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT
Sbjct: 300 LTLPLLFLGLSLLWTVLLDPGAVSAWLWSLTSETTLRRLRYTLSPLLELRANGLLPT 356
>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
Length = 1697
Score = 64.7 bits (156), Expect = 1e-10
Identities = 74/276 (26%), Positives = 126/276 (45%), Gaps = 33/276 (11%)
Query: 52 QELLLQLQKD-NRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQP 110
Q L+ Q Q++ R ++ K+E E+ R L+ + L+ E++R L R+R + +
Sbjct: 383 QALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRK 442
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
E REAA++ ER RR E R +E L Q +R+ QE+ L+S+ EL++
Sbjct: 443 -DIERREAAKQELERQRRLEWERIRRQELLNQKNRE-QEEIVRLNSKKKNLHLELEALNG 500
Query: 171 TEQQLAAQL-------VTLQNELELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
QQ++ +L T + ELE+ + +C L+ E K Q LQ + Q ++
Sbjct: 501 KHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQ--------EYQNKLI 552
Query: 222 QVRPHSDAKEVQVKVMEAAEELDAWQS--------GRELCD---GQLRGVQYSTESLMEE 270
+ P ++K M+ + D+ S ELC QL ++ T S + E
Sbjct: 553 YLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSE 612
Query: 271 MARADRETRLFGGPRALAIRRCVLGALQVLLTLPLL 306
M + + + G ++ +C+L L L L LL
Sbjct: 613 MDSFNNQLKC--GNMDDSVLQCLLSLLSCLNNLFLL 646
Score = 32.3 bits (72), Expect = 0.67
Identities = 33/167 (19%), Positives = 70/167 (41%), Gaps = 6/167 (3%)
Query: 120 RERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQL 179
+ +A R +E +R + +EQ R+ + + ++ + ELQ Q+ +Q +
Sbjct: 366 KRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKR 425
Query: 180 VTLQNELELAETKCALQEEKLQQDALQTAE-----AWAIFQEQTVVLQV-RPHSDAKEVQ 233
+ Q ELE + ++ + ++ A Q E W + Q ++ Q R + +
Sbjct: 426 LEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLN 485
Query: 234 VKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRL 280
K EL+A + G+L+ V+ ++ E+ D++ L
Sbjct: 486 SKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDL 532
>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
Length = 1249
Score = 64.7 bits (156), Expect = 1e-10
Identities = 74/276 (26%), Positives = 126/276 (45%), Gaps = 33/276 (11%)
Query: 52 QELLLQLQKD-NRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQP 110
Q L+ Q Q++ R ++ K+E E+ R L+ + L+ E++R L R+R + +
Sbjct: 383 QALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRK 442
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
E REAA++ ER RR E R +E L Q +R+ QE+ L+S+ EL++
Sbjct: 443 -DIERREAAKQELERQRRLEWERIRRQELLNQKNRE-QEEIVRLNSKKKNLHLELEALNG 500
Query: 171 TEQQLAAQL-------VTLQNELELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
QQ++ +L T + ELE+ + +C L+ E K Q LQ + Q ++
Sbjct: 501 KHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQ--------EYQNKLI 552
Query: 222 QVRPHSDAKEVQVKVMEAAEELDAWQS--------GRELCD---GQLRGVQYSTESLMEE 270
+ P ++K M+ + D+ S ELC QL ++ T S + E
Sbjct: 553 YLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSE 612
Query: 271 MARADRETRLFGGPRALAIRRCVLGALQVLLTLPLL 306
M + + + G ++ +C+L L L L LL
Sbjct: 613 MDSFNNQLKC--GNMDDSVLQCLLSLLSCLNNLFLL 646
Score = 32.3 bits (72), Expect = 0.67
Identities = 33/167 (19%), Positives = 70/167 (41%), Gaps = 6/167 (3%)
Query: 120 RERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQL 179
+ +A R +E +R + +EQ R+ + + ++ + ELQ Q+ +Q +
Sbjct: 366 KRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKR 425
Query: 180 VTLQNELELAETKCALQEEKLQQDALQTAE-----AWAIFQEQTVVLQV-RPHSDAKEVQ 233
+ Q ELE + ++ + ++ A Q E W + Q ++ Q R + +
Sbjct: 426 LEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLN 485
Query: 234 VKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRL 280
K EL+A + G+L+ V+ ++ E+ D++ L
Sbjct: 486 SKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDL 532
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 61.6 bits (148), Expect = 1e-09
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 19/249 (7%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQE--------LEKLMRGLEAESESLNQRLQD-LSERE 97
A+ A +EL LQ ++ R RQ + E LE R EAE +S + ++ E
Sbjct: 1534 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1593
Query: 98 RSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQ---LQEQWEEL 154
RSL AQ L+ EA A+++AE R R EEAER E + + + L+ Q EE+
Sbjct: 1594 RSLQEEHVAVAQ-LREEAERRAQQQAEAERAR-EEAERELERWQLKANEALRLRLQAEEV 1651
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-EKLQQDALQTAEAWAI 213
+ Q E + QK E + A+ E + + + A QE EK +Q A TA+
Sbjct: 1652 AQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLA 1710
Query: 214 FQEQTVVLQVRPHSDAKEVQVKVMEAAE---ELDAWQSGRELCDGQLRGVQYSTESLMEE 270
+++ + L+ ++ Q+ E A E A R+ + +L V+ E L+
Sbjct: 1711 AEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLAS 1770
Query: 271 MARADRETR 279
ARA+ E+R
Sbjct: 1771 KARAEEESR 1779
Score = 61.6 bits (148), Expect = 1e-09
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 7/204 (3%)
Query: 42 GSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLL 101
G+ +AA QEL+ +L+ + G Q++Q LE+ + L+ E+ + Q+ Q+L E E + +
Sbjct: 1703 GTAQQRLAAEQELI-RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL-EAELAKV 1760
Query: 102 RRRSQAAQPLQGEAREAARERAERVRRRLE-EAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + + A E +R +E+ ++RLE EA R +E E+ +R L+ EE Q
Sbjct: 1761 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAAR-LRALAEEAKRQRQL 1819
Query: 161 YGGELQSQKS-TEQQLAAQLVTLQNELEL-AETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+ Q++ E+ LA +L + L E + AL+E++ + + L+ FQ +
Sbjct: 1820 AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRR 1879
Query: 219 VVLQVRPH-SDAKEVQVKVMEAAE 241
+ Q H +D +E ++ +A++
Sbjct: 1880 LEEQAAQHKADIEERLAQLRKASD 1903
Score = 56.2 bits (134), Expect = 4e-08
Identities = 72/261 (27%), Positives = 105/261 (40%), Gaps = 32/261 (12%)
Query: 43 SVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQR-LQDLSERERSLL 101
S A A EL L+L GR R + L +AE E+ QR L ER R
Sbjct: 1933 SFEKAAAGKAELELEL------GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1986
Query: 102 RRRSQAAQPLQGEA---REAARERAERVRRRLEEAERHKEYLEQHS-RQLQEQWEELSSQ 157
R Q + + EA R+AA E ER++ ++EEA R +E EQ S RQLQ E +
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 158 L--------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEE-------KLQQ 202
L F + Q + T QQ + L L+ E E A EE + Q
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 203 DALQTAEAWAIFQEQTVVLQVRPHSDA------KEVQVKVMEAAEELDAWQSGRELCDGQ 256
Q EA + Q Q R + A KE + + A+ A ++ D +
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2166
Query: 257 LRGVQYSTESLMEEMARADRE 277
+ + E + + A+ ++E
Sbjct: 2167 MEKHKKFAEQTLRQKAQVEQE 2187
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/274 (23%), Positives = 114/274 (41%), Gaps = 52/274 (18%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLE------AESESLNQRLQDLSERERSL 100
A +E +Q +++ R++ +E E+L + E A++++ ++L+ +E+E +
Sbjct: 2089 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA- 2147
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
RR+QA Q + ++AA E+ ++ E+ R K +EQ L+ Q EE Q
Sbjct: 2148 --RRAQAEQAALRQ-KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2204
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--------ELAETKCAL----------------- 195
ELQ K+ + A Q ++ EL EL++ K +
Sbjct: 2205 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2264
Query: 196 ----QEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDA----------KEVQVKVMEAAE 241
+ EK++Q A + A QE + Q+ A KE V EA
Sbjct: 2265 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2324
Query: 242 ---ELDAWQSGRELCDGQLRGVQYSTESLMEEMA 272
E + Q +EL Q R +Q E + +++A
Sbjct: 2325 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2358
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/250 (24%), Positives = 112/250 (44%), Gaps = 35/250 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
Q L + ++ RQ ++E E+L R ++ ES+ Q +L+ R ++ + + L
Sbjct: 1476 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1535
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q A E R +AE RRL +AE + +RQ+Q E ELQS++++
Sbjct: 1536 Q--ALEELRLQAEEAERRLRQAE------VERARQVQVALETAQRSA---EAELQSKRAS 1584
Query: 172 EQQLAAQLV-TLQNE-------LELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
+ AQL +LQ E E AE + Q E+ +++A + E W + + + L
Sbjct: 1585 FAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL 1644
Query: 222 QVRPHSDAKEVQVKVMEAAE-----ELDAWQSG---------RELCDGQLRGVQYSTESL 267
+++ A++ + EA + E +A + G REL + +L + E
Sbjct: 1645 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1704
Query: 268 MEEMARADRE 277
++ A++E
Sbjct: 1705 AQQRLAAEQE 1714
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 57 QLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER----ERSLLRRRSQAAQPLQ 112
Q++++ R + +EL KL +EAE+ +L R +D ++R E +++ ++ A L
Sbjct: 2225 QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2284
Query: 113 GEAREAARER---------------------------AERVRRRLEEAERHKEYLEQHSR 145
A+EAAR R A R++ E ++ KE ++ +R
Sbjct: 2285 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2344
Query: 146 QLQEQWEELSSQL------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-- 197
+LQE E+++ QL F E + Q+ E A+ + L+ E++ + +E
Sbjct: 2345 RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-VAEMSRAQARAEEDA 2403
Query: 198 -----------EKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAW 246
EKL + L T E + Q + Q H DA+ ++ + E E +
Sbjct: 2404 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAELEREKEKL 2462
Query: 247 QSGRELCDGQLRGVQYST---ESLMEE 270
Q +L QL+ + T E L++E
Sbjct: 2463 QQEAKLL--QLKSEEMQTVQQEQLLQE 2487
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 30/265 (11%)
Query: 19 RRSLPPIVTPASRRLGPRGGRHL----GSVSTAMAATQELLLQLQKDNRDGRQRKQELEK 74
+ L P+ +PA + G + + T + L Q K + +R +E E+
Sbjct: 1290 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1349
Query: 75 LMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAE 134
L AE ++ E++R L +QA + EA+E + E V RR E A
Sbjct: 1350 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1409
Query: 135 RHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCA 194
+Q R +QE+ ++L E + Q Q AA+ L+ E E+ +
Sbjct: 1410 D----AQQQKRSIQEELQQLRQ-----SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1460
Query: 195 LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCD 254
L+ + Q+ + E A+ + A+E + + +A EE + + R++ D
Sbjct: 1461 LEATERQRGGAE-GELQAL------------RARAEEAEAQKRQAQEEAERLR--RQVQD 1505
Query: 255 GQLRGVQYSTE--SLMEEMARADRE 277
R Q E S ++ A A RE
Sbjct: 1506 ESQRKRQAEVELASRVKAEAEAARE 1530
Score = 44.7 bits (104), Expect = 1e-04
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 64/283 (22%)
Query: 45 STAMAATQELLLQLQKD---------NRDGRQRKQELEKLMRGLEAESESLNQRLQDLS- 94
+T + A E LLQ QK+ D Q Q+L + +G + E+ QR ++S
Sbjct: 2322 ATRLKAEAE-LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSA 2380
Query: 95 ERERSLLR---------RRSQAAQPLQGEARE----------AARER------------- 122
E ER LR R + AQ + +A E A +E+
Sbjct: 2381 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2440
Query: 123 ----AERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQ 178
AER+R + E ER KE L+Q ++ LQ + EE+ Q ++QL +
Sbjct: 2441 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-------------QTVQQEQLLQE 2487
Query: 179 LVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVME 238
LQ L+E LQ E+ + + A+ +FQ++ Q ++ Q E
Sbjct: 2488 TQALQQSF-LSEKDSLLQRERFIEQ--EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Query: 239 AAEELDAWQSGRELCDGQLRGVQYSTESLME-EMARADRETRL 280
+ + + R GV+ E L + E R +E L
Sbjct: 2545 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2587
Score = 43.1 bits (100), Expect = 4e-04
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 53/286 (18%)
Query: 32 RLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESES---LNQ 88
RL R G V +LL + Q R++ELE+L R L ES L
Sbjct: 1162 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1221
Query: 89 RLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQ---HSR 145
LQD RRR + Q + +A RE+ + + LEE ERH E +E+ ++
Sbjct: 1222 WLQDA--------RRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1273
Query: 146 QLQEQWEELSSQLFYYGGELQS----------QKSTEQQLA---------AQLVTLQNE- 185
Q ++ QL Y +L+ Q +E + ++L TL ++
Sbjct: 1274 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1333
Query: 186 -------LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS------DAKEV 232
L E + L E++ ++ + AE A ++Q + + + +AKE+
Sbjct: 1334 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKEL 1393
Query: 233 QVKVMEAA---EE--LDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q ++ E EE +DA Q R + + +L+ ++ S+E+ ++ AR
Sbjct: 1394 QQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKAR 1438
Score = 42.4 bits (98), Expect = 6e-04
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 20/186 (10%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-----------------LS 94
++LL + Q + K L + R +E E L Q QD
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2541
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E+ER L + A+ Q EA E R + E +++ ++ + +E L + +++L+EQ + L
Sbjct: 2542 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLL 2601
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q + S++ T Q+AA TL N + + A E + D L+ +
Sbjct: 2602 EEQ--HRAALAHSEEVTASQVAA-TKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRL 2658
Query: 215 QEQTVV 220
QE ++
Sbjct: 2659 QEAGIL 2664
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 28/199 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGL-EAESESLNQRLQDLSERERSLLRRRSQAAQP 110
+E+ Q + ++K+E E+ R +AE +++ QR +L+E+E L ++ Q A+
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR--ELAEQE---LEKQRQLAEG 1703
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
+ R AA + R+R E+ E+ ++ LE+ +LQ E +
Sbjct: 1704 T-AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR--------------EAAAATQ 1748
Query: 171 TEQQLAAQLVTLQNELEL-------AETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQV 223
Q+L A+L ++ E+E+ AE + EK +Q A + E+ L+
Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1808
Query: 224 RPHSDAKEVQVKVMEAAEE 242
++ Q+ +AA +
Sbjct: 1809 LAEEAKRQRQLAEEDAARQ 1827
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 38/165 (23%)
Query: 70 QELEKLMRGLEA---ESESLNQRLQDLSERERSL--LRRRSQAAQPLQGEARE---AARE 121
Q E+++R E E++++ L +L + SL LR +++A QP R+ A+E
Sbjct: 1099 QGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQE 1158
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQW--------------EELSSQLFYY------ 161
ER+++R E + E + QL E+W E+L QL YY
Sbjct: 1159 VGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADP 1218
Query: 162 -GGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDAL 205
G LQ + ++Q+ A + LA+++ A++E+ Q+ AL
Sbjct: 1219 LGAWLQDARRRQEQIQA--------MPLADSQ-AVREQLRQEQAL 1254
Score = 29.6 bits (65), Expect = 4.3
Identities = 63/282 (22%), Positives = 105/282 (37%), Gaps = 73/282 (25%)
Query: 52 QELLLQLQKDNRD-GRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLR-------- 102
QE +LQ+D +Q +E + R LEAE + ++L+ +E ER LR
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ---RQLEMSAEAERLKLRVAEMSRAQ 2396
Query: 103 -RRSQAAQPLQGEARE----------AARER-----------------AERVRRRLEEAE 134
R + AQ + +A E A +E+ AER+R + E E
Sbjct: 2397 ARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELE 2456
Query: 135 RHKEYLEQH----------------------SRQLQEQWEELSSQLFYYGGELQSQKSTE 172
R KE L+Q ++ LQ+ + L LQ ++ E
Sbjct: 2457 REKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL------LQRERFIE 2510
Query: 173 QQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEV 232
Q+ A Q+E+ A+ Q+ + QQ + A +E R +A+E
Sbjct: 2511 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-----RRQHEAEEG 2565
Query: 233 QVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+ E ++L+ + +E + L+EE RA
Sbjct: 2566 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2607
Score = 28.9 bits (63), Expect = 7.4
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 22/113 (19%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQE----LEKLMRGLEA----ESESLNQRLQDLSERERS 99
+ A+ E + Q + +G +RKQE LE+ R E E++ L ++LQ L E+ R+
Sbjct: 2548 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2607
Query: 100 LLRRRSQAA--------------QPLQGEAREAARERAERVRRRLEEAERHKE 138
L + L G A EA E + RR A+R +E
Sbjct: 2608 ALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQE 2660
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 61.6 bits (148), Expect = 1e-09
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 19/249 (7%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQE--------LEKLMRGLEAESESLNQRLQD-LSERE 97
A+ A +EL LQ ++ R RQ + E LE R EAE +S + ++ E
Sbjct: 1538 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1597
Query: 98 RSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQ---LQEQWEEL 154
RSL AQ L+ EA A+++AE R R EEAER E + + + L+ Q EE+
Sbjct: 1598 RSLQEEHVAVAQ-LREEAERRAQQQAEAERAR-EEAERELERWQLKANEALRLRLQAEEV 1655
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-EKLQQDALQTAEAWAI 213
+ Q E + QK E + A+ E + + + A QE EK +Q A TA+
Sbjct: 1656 AQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLA 1714
Query: 214 FQEQTVVLQVRPHSDAKEVQVKVMEAAE---ELDAWQSGRELCDGQLRGVQYSTESLMEE 270
+++ + L+ ++ Q+ E A E A R+ + +L V+ E L+
Sbjct: 1715 AEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLAS 1774
Query: 271 MARADRETR 279
ARA+ E+R
Sbjct: 1775 KARAEEESR 1783
Score = 61.6 bits (148), Expect = 1e-09
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 7/204 (3%)
Query: 42 GSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLL 101
G+ +AA QEL+ +L+ + G Q++Q LE+ + L+ E+ + Q+ Q+L E E + +
Sbjct: 1707 GTAQQRLAAEQELI-RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL-EAELAKV 1764
Query: 102 RRRSQAAQPLQGEAREAARERAERVRRRLE-EAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + + A E +R +E+ ++RLE EA R +E E+ +R L+ EE Q
Sbjct: 1765 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAAR-LRALAEEAKRQRQL 1823
Query: 161 YGGELQSQKS-TEQQLAAQLVTLQNELEL-AETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+ Q++ E+ LA +L + L E + AL+E++ + + L+ FQ +
Sbjct: 1824 AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRR 1883
Query: 219 VVLQVRPH-SDAKEVQVKVMEAAE 241
+ Q H +D +E ++ +A++
Sbjct: 1884 LEEQAAQHKADIEERLAQLRKASD 1907
Score = 56.2 bits (134), Expect = 4e-08
Identities = 72/261 (27%), Positives = 105/261 (40%), Gaps = 32/261 (12%)
Query: 43 SVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQR-LQDLSERERSLL 101
S A A EL L+L GR R + L +AE E+ QR L ER R
Sbjct: 1937 SFEKAAAGKAELELEL------GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1990
Query: 102 RRRSQAAQPLQGEA---REAARERAERVRRRLEEAERHKEYLEQHS-RQLQEQWEELSSQ 157
R Q + + EA R+AA E ER++ ++EEA R +E EQ S RQLQ E +
Sbjct: 1991 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2050
Query: 158 L--------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEE-------KLQQ 202
L F + Q + T QQ + L L+ E E A EE + Q
Sbjct: 2051 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2110
Query: 203 DALQTAEAWAIFQEQTVVLQVRPHSDA------KEVQVKVMEAAEELDAWQSGRELCDGQ 256
Q EA + Q Q R + A KE + + A+ A ++ D +
Sbjct: 2111 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2170
Query: 257 LRGVQYSTESLMEEMARADRE 277
+ + E + + A+ ++E
Sbjct: 2171 MEKHKKFAEQTLRQKAQVEQE 2191
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/274 (23%), Positives = 114/274 (41%), Gaps = 52/274 (18%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLE------AESESLNQRLQDLSERERSL 100
A +E +Q +++ R++ +E E+L + E A++++ ++L+ +E+E +
Sbjct: 2093 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA- 2151
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
RR+QA Q + ++AA E+ ++ E+ R K +EQ L+ Q EE Q
Sbjct: 2152 --RRAQAEQAALRQ-KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2208
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--------ELAETKCAL----------------- 195
ELQ K+ + A Q ++ EL EL++ K +
Sbjct: 2209 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2268
Query: 196 ----QEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDA----------KEVQVKVMEAAE 241
+ EK++Q A + A QE + Q+ A KE V EA
Sbjct: 2269 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2328
Query: 242 ---ELDAWQSGRELCDGQLRGVQYSTESLMEEMA 272
E + Q +EL Q R +Q E + +++A
Sbjct: 2329 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2362
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/250 (24%), Positives = 112/250 (44%), Gaps = 35/250 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
Q L + ++ RQ ++E E+L R ++ ES+ Q +L+ R ++ + + L
Sbjct: 1480 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1539
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q A E R +AE RRL +AE + +RQ+Q E ELQS++++
Sbjct: 1540 Q--ALEELRLQAEEAERRLRQAE------VERARQVQVALETAQRSA---EAELQSKRAS 1588
Query: 172 EQQLAAQLV-TLQNE-------LELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
+ AQL +LQ E E AE + Q E+ +++A + E W + + + L
Sbjct: 1589 FAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL 1648
Query: 222 QVRPHSDAKEVQVKVMEAAE-----ELDAWQSG---------RELCDGQLRGVQYSTESL 267
+++ A++ + EA + E +A + G REL + +L + E
Sbjct: 1649 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1708
Query: 268 MEEMARADRE 277
++ A++E
Sbjct: 1709 AQQRLAAEQE 1718
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 57 QLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER----ERSLLRRRSQAAQPLQ 112
Q++++ R + +EL KL +EAE+ +L R +D ++R E +++ ++ A L
Sbjct: 2229 QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2288
Query: 113 GEAREAARER---------------------------AERVRRRLEEAERHKEYLEQHSR 145
A+EAAR R A R++ E ++ KE ++ +R
Sbjct: 2289 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2348
Query: 146 QLQEQWEELSSQL------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-- 197
+LQE E+++ QL F E + Q+ E A+ + L+ E++ + +E
Sbjct: 2349 RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-VAEMSRAQARAEEDA 2407
Query: 198 -----------EKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAW 246
EKL + L T E + Q + Q H DA+ ++ + E E +
Sbjct: 2408 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAELEREKEKL 2466
Query: 247 QSGRELCDGQLRGVQYST---ESLMEE 270
Q +L QL+ + T E L++E
Sbjct: 2467 QQEAKLL--QLKSEEMQTVQQEQLLQE 2491
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 30/265 (11%)
Query: 19 RRSLPPIVTPASRRLGPRGGRHL----GSVSTAMAATQELLLQLQKDNRDGRQRKQELEK 74
+ L P+ +PA + G + + T + L Q K + +R +E E+
Sbjct: 1294 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1353
Query: 75 LMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAE 134
L AE ++ E++R L +QA + EA+E + E V RR E A
Sbjct: 1354 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1413
Query: 135 RHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCA 194
+Q R +QE+ ++L E + Q Q AA+ L+ E E+ +
Sbjct: 1414 D----AQQQKRSIQEELQQLRQ-----SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1464
Query: 195 LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCD 254
L+ + Q+ + E A+ + A+E + + +A EE + + R++ D
Sbjct: 1465 LEATERQRGGAE-GELQAL------------RARAEEAEAQKRQAQEEAERLR--RQVQD 1509
Query: 255 GQLRGVQYSTE--SLMEEMARADRE 277
R Q E S ++ A A RE
Sbjct: 1510 ESQRKRQAEVELASRVKAEAEAARE 1534
Score = 44.7 bits (104), Expect = 1e-04
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 64/283 (22%)
Query: 45 STAMAATQELLLQLQKD---------NRDGRQRKQELEKLMRGLEAESESLNQRLQDLS- 94
+T + A E LLQ QK+ D Q Q+L + +G + E+ QR ++S
Sbjct: 2326 ATRLKAEAE-LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSA 2384
Query: 95 ERERSLLR---------RRSQAAQPLQGEARE----------AARER------------- 122
E ER LR R + AQ + +A E A +E+
Sbjct: 2385 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2444
Query: 123 ----AERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQ 178
AER+R + E ER KE L+Q ++ LQ + EE+ Q ++QL +
Sbjct: 2445 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-------------QTVQQEQLLQE 2491
Query: 179 LVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVME 238
LQ L+E LQ E+ + + A+ +FQ++ Q ++ Q E
Sbjct: 2492 TQALQQSF-LSEKDSLLQRERFIEQ--EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2548
Query: 239 AAEELDAWQSGRELCDGQLRGVQYSTESLME-EMARADRETRL 280
+ + + R GV+ E L + E R +E L
Sbjct: 2549 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2591
Score = 43.1 bits (100), Expect = 4e-04
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 53/286 (18%)
Query: 32 RLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESES---LNQ 88
RL R G V +LL + Q R++ELE+L R L ES L
Sbjct: 1166 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1225
Query: 89 RLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQ---HSR 145
LQD RRR + Q + +A RE+ + + LEE ERH E +E+ ++
Sbjct: 1226 WLQDA--------RRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1277
Query: 146 QLQEQWEELSSQLFYYGGELQS----------QKSTEQQLA---------AQLVTLQNE- 185
Q ++ QL Y +L+ Q +E + ++L TL ++
Sbjct: 1278 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1337
Query: 186 -------LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS------DAKEV 232
L E + L E++ ++ + AE A ++Q + + + +AKE+
Sbjct: 1338 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKEL 1397
Query: 233 QVKVMEAA---EE--LDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q ++ E EE +DA Q R + + +L+ ++ S+E+ ++ AR
Sbjct: 1398 QQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKAR 1442
Score = 42.4 bits (98), Expect = 6e-04
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 20/186 (10%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-----------------LS 94
++LL + Q + K L + R +E E L Q QD
Sbjct: 2486 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2545
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E+ER L + A+ Q EA E R + E +++ ++ + +E L + +++L+EQ + L
Sbjct: 2546 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLL 2605
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q + S++ T Q+AA TL N + + A E + D L+ +
Sbjct: 2606 EEQ--HRAALAHSEEVTASQVAA-TKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRL 2662
Query: 215 QEQTVV 220
QE ++
Sbjct: 2663 QEAGIL 2668
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 28/199 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGL-EAESESLNQRLQDLSERERSLLRRRSQAAQP 110
+E+ Q + ++K+E E+ R +AE +++ QR +L+E+E L ++ Q A+
Sbjct: 1653 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR--ELAEQE---LEKQRQLAEG 1707
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
+ R AA + R+R E+ E+ ++ LE+ +LQ E +
Sbjct: 1708 T-AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR--------------EAAAATQ 1752
Query: 171 TEQQLAAQLVTLQNELEL-------AETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQV 223
Q+L A+L ++ E+E+ AE + EK +Q A + E+ L+
Sbjct: 1753 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1812
Query: 224 RPHSDAKEVQVKVMEAAEE 242
++ Q+ +AA +
Sbjct: 1813 LAEEAKRQRQLAEEDAARQ 1831
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 38/165 (23%)
Query: 70 QELEKLMRGLEA---ESESLNQRLQDLSERERSL--LRRRSQAAQPLQGEARE---AARE 121
Q E+++R E E++++ L +L + SL LR +++A QP R+ A+E
Sbjct: 1103 QGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQE 1162
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQW--------------EELSSQLFYY------ 161
ER+++R E + E + QL E+W E+L QL YY
Sbjct: 1163 VGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADP 1222
Query: 162 -GGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDAL 205
G LQ + ++Q+ A + LA+++ A++E+ Q+ AL
Sbjct: 1223 LGAWLQDARRRQEQIQA--------MPLADSQ-AVREQLRQEQAL 1258
Score = 29.6 bits (65), Expect = 4.3
Identities = 63/282 (22%), Positives = 105/282 (37%), Gaps = 73/282 (25%)
Query: 52 QELLLQLQKDNRD-GRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLR-------- 102
QE +LQ+D +Q +E + R LEAE + ++L+ +E ER LR
Sbjct: 2344 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ---RQLEMSAEAERLKLRVAEMSRAQ 2400
Query: 103 -RRSQAAQPLQGEARE----------AARER-----------------AERVRRRLEEAE 134
R + AQ + +A E A +E+ AER+R + E E
Sbjct: 2401 ARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELE 2460
Query: 135 RHKEYLEQH----------------------SRQLQEQWEELSSQLFYYGGELQSQKSTE 172
R KE L+Q ++ LQ+ + L LQ ++ E
Sbjct: 2461 REKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL------LQRERFIE 2514
Query: 173 QQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEV 232
Q+ A Q+E+ A+ Q+ + QQ + A +E R +A+E
Sbjct: 2515 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-----RRQHEAEEG 2569
Query: 233 QVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+ E ++L+ + +E + L+EE RA
Sbjct: 2570 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2611
Score = 28.9 bits (63), Expect = 7.4
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 22/113 (19%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQE----LEKLMRGLEA----ESESLNQRLQDLSERERS 99
+ A+ E + Q + +G +RKQE LE+ R E E++ L ++LQ L E+ R+
Sbjct: 2552 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2611
Query: 100 LLRRRSQAA--------------QPLQGEAREAARERAERVRRRLEEAERHKE 138
L + L G A EA E + RR A+R +E
Sbjct: 2612 ALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQE 2664
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 61.6 bits (148), Expect = 1e-09
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 19/249 (7%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQE--------LEKLMRGLEAESESLNQRLQD-LSERE 97
A+ A +EL LQ ++ R RQ + E LE R EAE +S + ++ E
Sbjct: 1534 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1593
Query: 98 RSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQ---LQEQWEEL 154
RSL AQ L+ EA A+++AE R R EEAER E + + + L+ Q EE+
Sbjct: 1594 RSLQEEHVAVAQ-LREEAERRAQQQAEAERAR-EEAERELERWQLKANEALRLRLQAEEV 1651
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-EKLQQDALQTAEAWAI 213
+ Q E + QK E + A+ E + + + A QE EK +Q A TA+
Sbjct: 1652 AQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLA 1710
Query: 214 FQEQTVVLQVRPHSDAKEVQVKVMEAAE---ELDAWQSGRELCDGQLRGVQYSTESLMEE 270
+++ + L+ ++ Q+ E A E A R+ + +L V+ E L+
Sbjct: 1711 AEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLAS 1770
Query: 271 MARADRETR 279
ARA+ E+R
Sbjct: 1771 KARAEEESR 1779
Score = 61.6 bits (148), Expect = 1e-09
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 7/204 (3%)
Query: 42 GSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLL 101
G+ +AA QEL+ +L+ + G Q++Q LE+ + L+ E+ + Q+ Q+L E E + +
Sbjct: 1703 GTAQQRLAAEQELI-RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL-EAELAKV 1760
Query: 102 RRRSQAAQPLQGEAREAARERAERVRRRLE-EAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + + A E +R +E+ ++RLE EA R +E E+ +R L+ EE Q
Sbjct: 1761 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAAR-LRALAEEAKRQRQL 1819
Query: 161 YGGELQSQKS-TEQQLAAQLVTLQNELEL-AETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+ Q++ E+ LA +L + L E + AL+E++ + + L+ FQ +
Sbjct: 1820 AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRR 1879
Query: 219 VVLQVRPH-SDAKEVQVKVMEAAE 241
+ Q H +D +E ++ +A++
Sbjct: 1880 LEEQAAQHKADIEERLAQLRKASD 1903
Score = 56.2 bits (134), Expect = 4e-08
Identities = 72/261 (27%), Positives = 105/261 (40%), Gaps = 32/261 (12%)
Query: 43 SVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQR-LQDLSERERSLL 101
S A A EL L+L GR R + L +AE E+ QR L ER R
Sbjct: 1933 SFEKAAAGKAELELEL------GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1986
Query: 102 RRRSQAAQPLQGEA---REAARERAERVRRRLEEAERHKEYLEQHS-RQLQEQWEELSSQ 157
R Q + + EA R+AA E ER++ ++EEA R +E EQ S RQLQ E +
Sbjct: 1987 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2046
Query: 158 L--------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEE-------KLQQ 202
L F + Q + T QQ + L L+ E E A EE + Q
Sbjct: 2047 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2106
Query: 203 DALQTAEAWAIFQEQTVVLQVRPHSDA------KEVQVKVMEAAEELDAWQSGRELCDGQ 256
Q EA + Q Q R + A KE + + A+ A ++ D +
Sbjct: 2107 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2166
Query: 257 LRGVQYSTESLMEEMARADRE 277
+ + E + + A+ ++E
Sbjct: 2167 MEKHKKFAEQTLRQKAQVEQE 2187
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/274 (23%), Positives = 114/274 (41%), Gaps = 52/274 (18%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLE------AESESLNQRLQDLSERERSL 100
A +E +Q +++ R++ +E E+L + E A++++ ++L+ +E+E +
Sbjct: 2089 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA- 2147
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
RR+QA Q + ++AA E+ ++ E+ R K +EQ L+ Q EE Q
Sbjct: 2148 --RRAQAEQAALRQ-KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2204
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--------ELAETKCAL----------------- 195
ELQ K+ + A Q ++ EL EL++ K +
Sbjct: 2205 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2264
Query: 196 ----QEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDA----------KEVQVKVMEAAE 241
+ EK++Q A + A QE + Q+ A KE V EA
Sbjct: 2265 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2324
Query: 242 ---ELDAWQSGRELCDGQLRGVQYSTESLMEEMA 272
E + Q +EL Q R +Q E + +++A
Sbjct: 2325 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2358
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/250 (24%), Positives = 112/250 (44%), Gaps = 35/250 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
Q L + ++ RQ ++E E+L R ++ ES+ Q +L+ R ++ + + L
Sbjct: 1476 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1535
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q A E R +AE RRL +AE + +RQ+Q E ELQS++++
Sbjct: 1536 Q--ALEELRLQAEEAERRLRQAE------VERARQVQVALETAQRSA---EAELQSKRAS 1584
Query: 172 EQQLAAQLV-TLQNE-------LELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
+ AQL +LQ E E AE + Q E+ +++A + E W + + + L
Sbjct: 1585 FAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL 1644
Query: 222 QVRPHSDAKEVQVKVMEAAE-----ELDAWQSG---------RELCDGQLRGVQYSTESL 267
+++ A++ + EA + E +A + G REL + +L + E
Sbjct: 1645 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1704
Query: 268 MEEMARADRE 277
++ A++E
Sbjct: 1705 AQQRLAAEQE 1714
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 57 QLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER----ERSLLRRRSQAAQPLQ 112
Q++++ R + +EL KL +EAE+ +L R +D ++R E +++ ++ A L
Sbjct: 2225 QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2284
Query: 113 GEAREAARER---------------------------AERVRRRLEEAERHKEYLEQHSR 145
A+EAAR R A R++ E ++ KE ++ +R
Sbjct: 2285 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2344
Query: 146 QLQEQWEELSSQL------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-- 197
+LQE E+++ QL F E + Q+ E A+ + L+ E++ + +E
Sbjct: 2345 RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-VAEMSRAQARAEEDA 2403
Query: 198 -----------EKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAW 246
EKL + L T E + Q + Q H DA+ ++ + E E +
Sbjct: 2404 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAELEREKEKL 2462
Query: 247 QSGRELCDGQLRGVQYST---ESLMEE 270
Q +L QL+ + T E L++E
Sbjct: 2463 QQEAKLL--QLKSEEMQTVQQEQLLQE 2487
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 30/265 (11%)
Query: 19 RRSLPPIVTPASRRLGPRGGRHL----GSVSTAMAATQELLLQLQKDNRDGRQRKQELEK 74
+ L P+ +PA + G + + T + L Q K + +R +E E+
Sbjct: 1290 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1349
Query: 75 LMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAE 134
L AE ++ E++R L +QA + EA+E + E V RR E A
Sbjct: 1350 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1409
Query: 135 RHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCA 194
+Q R +QE+ ++L E + Q Q AA+ L+ E E+ +
Sbjct: 1410 D----AQQQKRSIQEELQQLRQ-----SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1460
Query: 195 LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCD 254
L+ + Q+ + E A+ + A+E + + +A EE + + R++ D
Sbjct: 1461 LEATERQRGGAE-GELQAL------------RARAEEAEAQKRQAQEEAERLR--RQVQD 1505
Query: 255 GQLRGVQYSTE--SLMEEMARADRE 277
R Q E S ++ A A RE
Sbjct: 1506 ESQRKRQAEVELASRVKAEAEAARE 1530
Score = 44.7 bits (104), Expect = 1e-04
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 64/283 (22%)
Query: 45 STAMAATQELLLQLQKD---------NRDGRQRKQELEKLMRGLEAESESLNQRLQDLS- 94
+T + A E LLQ QK+ D Q Q+L + +G + E+ QR ++S
Sbjct: 2322 ATRLKAEAE-LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSA 2380
Query: 95 ERERSLLR---------RRSQAAQPLQGEARE----------AARER------------- 122
E ER LR R + AQ + +A E A +E+
Sbjct: 2381 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2440
Query: 123 ----AERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQ 178
AER+R + E ER KE L+Q ++ LQ + EE+ Q ++QL +
Sbjct: 2441 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-------------QTVQQEQLLQE 2487
Query: 179 LVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVME 238
LQ L+E LQ E+ + + A+ +FQ++ Q ++ Q E
Sbjct: 2488 TQALQQSF-LSEKDSLLQRERFIEQ--EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544
Query: 239 AAEELDAWQSGRELCDGQLRGVQYSTESLME-EMARADRETRL 280
+ + + R GV+ E L + E R +E L
Sbjct: 2545 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2587
Score = 43.1 bits (100), Expect = 4e-04
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 53/286 (18%)
Query: 32 RLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESES---LNQ 88
RL R G V +LL + Q R++ELE+L R L ES L
Sbjct: 1162 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1221
Query: 89 RLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQ---HSR 145
LQD RRR + Q + +A RE+ + + LEE ERH E +E+ ++
Sbjct: 1222 WLQDA--------RRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1273
Query: 146 QLQEQWEELSSQLFYYGGELQS----------QKSTEQQLA---------AQLVTLQNE- 185
Q ++ QL Y +L+ Q +E + ++L TL ++
Sbjct: 1274 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1333
Query: 186 -------LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS------DAKEV 232
L E + L E++ ++ + AE A ++Q + + + +AKE+
Sbjct: 1334 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKEL 1393
Query: 233 QVKVMEAA---EE--LDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q ++ E EE +DA Q R + + +L+ ++ S+E+ ++ AR
Sbjct: 1394 QQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKAR 1438
Score = 42.4 bits (98), Expect = 6e-04
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 20/186 (10%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-----------------LS 94
++LL + Q + K L + R +E E L Q QD
Sbjct: 2482 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2541
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E+ER L + A+ Q EA E R + E +++ ++ + +E L + +++L+EQ + L
Sbjct: 2542 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLL 2601
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q + S++ T Q+AA TL N + + A E + D L+ +
Sbjct: 2602 EEQ--HRAALAHSEEVTASQVAA-TKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRL 2658
Query: 215 QEQTVV 220
QE ++
Sbjct: 2659 QEAGIL 2664
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 28/199 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGL-EAESESLNQRLQDLSERERSLLRRRSQAAQP 110
+E+ Q + ++K+E E+ R +AE +++ QR +L+E+E L ++ Q A+
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR--ELAEQE---LEKQRQLAEG 1703
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
+ R AA + R+R E+ E+ ++ LE+ +LQ E +
Sbjct: 1704 T-AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR--------------EAAAATQ 1748
Query: 171 TEQQLAAQLVTLQNELEL-------AETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQV 223
Q+L A+L ++ E+E+ AE + EK +Q A + E+ L+
Sbjct: 1749 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1808
Query: 224 RPHSDAKEVQVKVMEAAEE 242
++ Q+ +AA +
Sbjct: 1809 LAEEAKRQRQLAEEDAARQ 1827
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 38/165 (23%)
Query: 70 QELEKLMRGLEA---ESESLNQRLQDLSERERSL--LRRRSQAAQPLQGEARE---AARE 121
Q E+++R E E++++ L +L + SL LR +++A QP R+ A+E
Sbjct: 1099 QGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQE 1158
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQW--------------EELSSQLFYY------ 161
ER+++R E + E + QL E+W E+L QL YY
Sbjct: 1159 VGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADP 1218
Query: 162 -GGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDAL 205
G LQ + ++Q+ A + LA+++ A++E+ Q+ AL
Sbjct: 1219 LGAWLQDARRRQEQIQA--------MPLADSQ-AVREQLRQEQAL 1254
Score = 29.6 bits (65), Expect = 4.3
Identities = 63/282 (22%), Positives = 105/282 (37%), Gaps = 73/282 (25%)
Query: 52 QELLLQLQKDNRD-GRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLR-------- 102
QE +LQ+D +Q +E + R LEAE + ++L+ +E ER LR
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ---RQLEMSAEAERLKLRVAEMSRAQ 2396
Query: 103 -RRSQAAQPLQGEARE----------AARER-----------------AERVRRRLEEAE 134
R + AQ + +A E A +E+ AER+R + E E
Sbjct: 2397 ARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELE 2456
Query: 135 RHKEYLEQH----------------------SRQLQEQWEELSSQLFYYGGELQSQKSTE 172
R KE L+Q ++ LQ+ + L LQ ++ E
Sbjct: 2457 REKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL------LQRERFIE 2510
Query: 173 QQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEV 232
Q+ A Q+E+ A+ Q+ + QQ + A +E R +A+E
Sbjct: 2511 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-----RRQHEAEEG 2565
Query: 233 QVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+ E ++L+ + +E + L+EE RA
Sbjct: 2566 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2607
Score = 28.9 bits (63), Expect = 7.4
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 22/113 (19%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQE----LEKLMRGLEA----ESESLNQRLQDLSERERS 99
+ A+ E + Q + +G +RKQE LE+ R E E++ L ++LQ L E+ R+
Sbjct: 2548 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2607
Query: 100 LLRRRSQAA--------------QPLQGEAREAARERAERVRRRLEEAERHKE 138
L + L G A EA E + RR A+R +E
Sbjct: 2608 ALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQE 2660
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 61.6 bits (148), Expect = 1e-09
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 19/249 (7%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQE--------LEKLMRGLEAESESLNQRLQD-LSERE 97
A+ A +EL LQ ++ R RQ + E LE R EAE +S + ++ E
Sbjct: 1502 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1561
Query: 98 RSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQ---LQEQWEEL 154
RSL AQ L+ EA A+++AE R R EEAER E + + + L+ Q EE+
Sbjct: 1562 RSLQEEHVAVAQ-LREEAERRAQQQAEAERAR-EEAERELERWQLKANEALRLRLQAEEV 1619
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-EKLQQDALQTAEAWAI 213
+ Q E + QK E + A+ E + + + A QE EK +Q A TA+
Sbjct: 1620 AQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLA 1678
Query: 214 FQEQTVVLQVRPHSDAKEVQVKVMEAAE---ELDAWQSGRELCDGQLRGVQYSTESLMEE 270
+++ + L+ ++ Q+ E A E A R+ + +L V+ E L+
Sbjct: 1679 AEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLAS 1738
Query: 271 MARADRETR 279
ARA+ E+R
Sbjct: 1739 KARAEEESR 1747
Score = 61.6 bits (148), Expect = 1e-09
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 7/204 (3%)
Query: 42 GSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLL 101
G+ +AA QEL+ +L+ + G Q++Q LE+ + L+ E+ + Q+ Q+L E E + +
Sbjct: 1671 GTAQQRLAAEQELI-RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL-EAELAKV 1728
Query: 102 RRRSQAAQPLQGEAREAARERAERVRRRLE-EAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + + A E +R +E+ ++RLE EA R +E E+ +R L+ EE Q
Sbjct: 1729 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAAR-LRALAEEAKRQRQL 1787
Query: 161 YGGELQSQKS-TEQQLAAQLVTLQNELEL-AETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+ Q++ E+ LA +L + L E + AL+E++ + + L+ FQ +
Sbjct: 1788 AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRR 1847
Query: 219 VVLQVRPH-SDAKEVQVKVMEAAE 241
+ Q H +D +E ++ +A++
Sbjct: 1848 LEEQAAQHKADIEERLAQLRKASD 1871
Score = 56.2 bits (134), Expect = 4e-08
Identities = 72/261 (27%), Positives = 105/261 (40%), Gaps = 32/261 (12%)
Query: 43 SVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQR-LQDLSERERSLL 101
S A A EL L+L GR R + L +AE E+ QR L ER R
Sbjct: 1901 SFEKAAAGKAELELEL------GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1954
Query: 102 RRRSQAAQPLQGEA---REAARERAERVRRRLEEAERHKEYLEQHS-RQLQEQWEELSSQ 157
R Q + + EA R+AA E ER++ ++EEA R +E EQ S RQLQ E +
Sbjct: 1955 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2014
Query: 158 L--------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEE-------KLQQ 202
L F + Q + T QQ + L L+ E E A EE + Q
Sbjct: 2015 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2074
Query: 203 DALQTAEAWAIFQEQTVVLQVRPHSDA------KEVQVKVMEAAEELDAWQSGRELCDGQ 256
Q EA + Q Q R + A KE + + A+ A ++ D +
Sbjct: 2075 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2134
Query: 257 LRGVQYSTESLMEEMARADRE 277
+ + E + + A+ ++E
Sbjct: 2135 MEKHKKFAEQTLRQKAQVEQE 2155
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/274 (23%), Positives = 114/274 (41%), Gaps = 52/274 (18%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLE------AESESLNQRLQDLSERERSL 100
A +E +Q +++ R++ +E E+L + E A++++ ++L+ +E+E +
Sbjct: 2057 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA- 2115
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
RR+QA Q + ++AA E+ ++ E+ R K +EQ L+ Q EE Q
Sbjct: 2116 --RRAQAEQAALRQ-KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2172
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--------ELAETKCAL----------------- 195
ELQ K+ + A Q ++ EL EL++ K +
Sbjct: 2173 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2232
Query: 196 ----QEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDA----------KEVQVKVMEAAE 241
+ EK++Q A + A QE + Q+ A KE V EA
Sbjct: 2233 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2292
Query: 242 ---ELDAWQSGRELCDGQLRGVQYSTESLMEEMA 272
E + Q +EL Q R +Q E + +++A
Sbjct: 2293 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2326
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/250 (24%), Positives = 112/250 (44%), Gaps = 35/250 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
Q L + ++ RQ ++E E+L R ++ ES+ Q +L+ R ++ + + L
Sbjct: 1444 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1503
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q A E R +AE RRL +AE + +RQ+Q E ELQS++++
Sbjct: 1504 Q--ALEELRLQAEEAERRLRQAE------VERARQVQVALETAQRSA---EAELQSKRAS 1552
Query: 172 EQQLAAQLV-TLQNE-------LELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
+ AQL +LQ E E AE + Q E+ +++A + E W + + + L
Sbjct: 1553 FAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL 1612
Query: 222 QVRPHSDAKEVQVKVMEAAE-----ELDAWQSG---------RELCDGQLRGVQYSTESL 267
+++ A++ + EA + E +A + G REL + +L + E
Sbjct: 1613 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1672
Query: 268 MEEMARADRE 277
++ A++E
Sbjct: 1673 AQQRLAAEQE 1682
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 57 QLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER----ERSLLRRRSQAAQPLQ 112
Q++++ R + +EL KL +EAE+ +L R +D ++R E +++ ++ A L
Sbjct: 2193 QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2252
Query: 113 GEAREAARER---------------------------AERVRRRLEEAERHKEYLEQHSR 145
A+EAAR R A R++ E ++ KE ++ +R
Sbjct: 2253 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2312
Query: 146 QLQEQWEELSSQL------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-- 197
+LQE E+++ QL F E + Q+ E A+ + L+ E++ + +E
Sbjct: 2313 RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-VAEMSRAQARAEEDA 2371
Query: 198 -----------EKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAW 246
EKL + L T E + Q + Q H DA+ ++ + E E +
Sbjct: 2372 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAELEREKEKL 2430
Query: 247 QSGRELCDGQLRGVQYST---ESLMEE 270
Q +L QL+ + T E L++E
Sbjct: 2431 QQEAKLL--QLKSEEMQTVQQEQLLQE 2455
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 30/265 (11%)
Query: 19 RRSLPPIVTPASRRLGPRGGRHL----GSVSTAMAATQELLLQLQKDNRDGRQRKQELEK 74
+ L P+ +PA + G + + T + L Q K + +R +E E+
Sbjct: 1258 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1317
Query: 75 LMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAE 134
L AE ++ E++R L +QA + EA+E + E V RR E A
Sbjct: 1318 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1377
Query: 135 RHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCA 194
+Q R +QE+ ++L E + Q Q AA+ L+ E E+ +
Sbjct: 1378 D----AQQQKRSIQEELQQLRQ-----SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1428
Query: 195 LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCD 254
L+ + Q+ + E A+ + A+E + + +A EE + + R++ D
Sbjct: 1429 LEATERQRGGAE-GELQAL------------RARAEEAEAQKRQAQEEAERLR--RQVQD 1473
Query: 255 GQLRGVQYSTE--SLMEEMARADRE 277
R Q E S ++ A A RE
Sbjct: 1474 ESQRKRQAEVELASRVKAEAEAARE 1498
Score = 44.7 bits (104), Expect = 1e-04
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 64/283 (22%)
Query: 45 STAMAATQELLLQLQKD---------NRDGRQRKQELEKLMRGLEAESESLNQRLQDLS- 94
+T + A E LLQ QK+ D Q Q+L + +G + E+ QR ++S
Sbjct: 2290 ATRLKAEAE-LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSA 2348
Query: 95 ERERSLLR---------RRSQAAQPLQGEARE----------AARER------------- 122
E ER LR R + AQ + +A E A +E+
Sbjct: 2349 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2408
Query: 123 ----AERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQ 178
AER+R + E ER KE L+Q ++ LQ + EE+ Q ++QL +
Sbjct: 2409 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-------------QTVQQEQLLQE 2455
Query: 179 LVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVME 238
LQ L+E LQ E+ + + A+ +FQ++ Q ++ Q E
Sbjct: 2456 TQALQQSF-LSEKDSLLQRERFIEQ--EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2512
Query: 239 AAEELDAWQSGRELCDGQLRGVQYSTESLME-EMARADRETRL 280
+ + + R GV+ E L + E R +E L
Sbjct: 2513 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2555
Score = 43.1 bits (100), Expect = 4e-04
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 53/286 (18%)
Query: 32 RLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESES---LNQ 88
RL R G V +LL + Q R++ELE+L R L ES L
Sbjct: 1130 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1189
Query: 89 RLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQ---HSR 145
LQD RRR + Q + +A RE+ + + LEE ERH E +E+ ++
Sbjct: 1190 WLQDA--------RRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1241
Query: 146 QLQEQWEELSSQLFYYGGELQS----------QKSTEQQLA---------AQLVTLQNE- 185
Q ++ QL Y +L+ Q +E + ++L TL ++
Sbjct: 1242 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1301
Query: 186 -------LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS------DAKEV 232
L E + L E++ ++ + AE A ++Q + + + +AKE+
Sbjct: 1302 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKEL 1361
Query: 233 QVKVMEAA---EE--LDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q ++ E EE +DA Q R + + +L+ ++ S+E+ ++ AR
Sbjct: 1362 QQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKAR 1406
Score = 42.4 bits (98), Expect = 6e-04
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 20/186 (10%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-----------------LS 94
++LL + Q + K L + R +E E L Q QD
Sbjct: 2450 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2509
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E+ER L + A+ Q EA E R + E +++ ++ + +E L + +++L+EQ + L
Sbjct: 2510 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLL 2569
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q + S++ T Q+AA TL N + + A E + D L+ +
Sbjct: 2570 EEQ--HRAALAHSEEVTASQVAA-TKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRL 2626
Query: 215 QEQTVV 220
QE ++
Sbjct: 2627 QEAGIL 2632
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 28/199 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGL-EAESESLNQRLQDLSERERSLLRRRSQAAQP 110
+E+ Q + ++K+E E+ R +AE +++ QR +L+E+E L ++ Q A+
Sbjct: 1617 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR--ELAEQE---LEKQRQLAEG 1671
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
+ R AA + R+R E+ E+ ++ LE+ +LQ E +
Sbjct: 1672 T-AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR--------------EAAAATQ 1716
Query: 171 TEQQLAAQLVTLQNELEL-------AETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQV 223
Q+L A+L ++ E+E+ AE + EK +Q A + E+ L+
Sbjct: 1717 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1776
Query: 224 RPHSDAKEVQVKVMEAAEE 242
++ Q+ +AA +
Sbjct: 1777 LAEEAKRQRQLAEEDAARQ 1795
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 38/165 (23%)
Query: 70 QELEKLMRGLEA---ESESLNQRLQDLSERERSL--LRRRSQAAQPLQGEARE---AARE 121
Q E+++R E E++++ L +L + SL LR +++A QP R+ A+E
Sbjct: 1067 QGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQE 1126
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQW--------------EELSSQLFYY------ 161
ER+++R E + E + QL E+W E+L QL YY
Sbjct: 1127 VGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADP 1186
Query: 162 -GGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDAL 205
G LQ + ++Q+ A + LA+++ A++E+ Q+ AL
Sbjct: 1187 LGAWLQDARRRQEQIQA--------MPLADSQ-AVREQLRQEQAL 1222
Score = 29.6 bits (65), Expect = 4.3
Identities = 63/282 (22%), Positives = 105/282 (37%), Gaps = 73/282 (25%)
Query: 52 QELLLQLQKDNRD-GRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLR-------- 102
QE +LQ+D +Q +E + R LEAE + ++L+ +E ER LR
Sbjct: 2308 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ---RQLEMSAEAERLKLRVAEMSRAQ 2364
Query: 103 -RRSQAAQPLQGEARE----------AARER-----------------AERVRRRLEEAE 134
R + AQ + +A E A +E+ AER+R + E E
Sbjct: 2365 ARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELE 2424
Query: 135 RHKEYLEQH----------------------SRQLQEQWEELSSQLFYYGGELQSQKSTE 172
R KE L+Q ++ LQ+ + L LQ ++ E
Sbjct: 2425 REKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL------LQRERFIE 2478
Query: 173 QQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEV 232
Q+ A Q+E+ A+ Q+ + QQ + A +E R +A+E
Sbjct: 2479 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-----RRQHEAEEG 2533
Query: 233 QVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+ E ++L+ + +E + L+EE RA
Sbjct: 2534 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2575
Score = 28.9 bits (63), Expect = 7.4
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 22/113 (19%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQE----LEKLMRGLEA----ESESLNQRLQDLSERERS 99
+ A+ E + Q + +G +RKQE LE+ R E E++ L ++LQ L E+ R+
Sbjct: 2516 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2575
Query: 100 LLRRRSQAA--------------QPLQGEAREAARERAERVRRRLEEAERHKE 138
L + L G A EA E + RR A+R +E
Sbjct: 2576 ALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQE 2628
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 61.6 bits (148), Expect = 1e-09
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 19/249 (7%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQE--------LEKLMRGLEAESESLNQRLQD-LSERE 97
A+ A +EL LQ ++ R RQ + E LE R EAE +S + ++ E
Sbjct: 1671 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1730
Query: 98 RSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQ---LQEQWEEL 154
RSL AQ L+ EA A+++AE R R EEAER E + + + L+ Q EE+
Sbjct: 1731 RSLQEEHVAVAQ-LREEAERRAQQQAEAERAR-EEAERELERWQLKANEALRLRLQAEEV 1788
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-EKLQQDALQTAEAWAI 213
+ Q E + QK E + A+ E + + + A QE EK +Q A TA+
Sbjct: 1789 AQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLA 1847
Query: 214 FQEQTVVLQVRPHSDAKEVQVKVMEAAE---ELDAWQSGRELCDGQLRGVQYSTESLMEE 270
+++ + L+ ++ Q+ E A E A R+ + +L V+ E L+
Sbjct: 1848 AEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLAS 1907
Query: 271 MARADRETR 279
ARA+ E+R
Sbjct: 1908 KARAEEESR 1916
Score = 61.6 bits (148), Expect = 1e-09
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 7/204 (3%)
Query: 42 GSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLL 101
G+ +AA QEL+ +L+ + G Q++Q LE+ + L+ E+ + Q+ Q+L E E + +
Sbjct: 1840 GTAQQRLAAEQELI-RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL-EAELAKV 1897
Query: 102 RRRSQAAQPLQGEAREAARERAERVRRRLE-EAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + + A E +R +E+ ++RLE EA R +E E+ +R L+ EE Q
Sbjct: 1898 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAAR-LRALAEEAKRQRQL 1956
Query: 161 YGGELQSQKS-TEQQLAAQLVTLQNELEL-AETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+ Q++ E+ LA +L + L E + AL+E++ + + L+ FQ +
Sbjct: 1957 AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRR 2016
Query: 219 VVLQVRPH-SDAKEVQVKVMEAAE 241
+ Q H +D +E ++ +A++
Sbjct: 2017 LEEQAAQHKADIEERLAQLRKASD 2040
Score = 56.2 bits (134), Expect = 4e-08
Identities = 72/261 (27%), Positives = 105/261 (40%), Gaps = 32/261 (12%)
Query: 43 SVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQR-LQDLSERERSLL 101
S A A EL L+L GR R + L +AE E+ QR L ER R
Sbjct: 2070 SFEKAAAGKAELELEL------GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 2123
Query: 102 RRRSQAAQPLQGEA---REAARERAERVRRRLEEAERHKEYLEQHS-RQLQEQWEELSSQ 157
R Q + + EA R+AA E ER++ ++EEA R +E EQ S RQLQ E +
Sbjct: 2124 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2183
Query: 158 L--------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEE-------KLQQ 202
L F + Q + T QQ + L L+ E E A EE + Q
Sbjct: 2184 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2243
Query: 203 DALQTAEAWAIFQEQTVVLQVRPHSDA------KEVQVKVMEAAEELDAWQSGRELCDGQ 256
Q EA + Q Q R + A KE + + A+ A ++ D +
Sbjct: 2244 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2303
Query: 257 LRGVQYSTESLMEEMARADRE 277
+ + E + + A+ ++E
Sbjct: 2304 MEKHKKFAEQTLRQKAQVEQE 2324
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/274 (23%), Positives = 114/274 (41%), Gaps = 52/274 (18%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLE------AESESLNQRLQDLSERERSL 100
A +E +Q +++ R++ +E E+L + E A++++ ++L+ +E+E +
Sbjct: 2226 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA- 2284
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
RR+QA Q + ++AA E+ ++ E+ R K +EQ L+ Q EE Q
Sbjct: 2285 --RRAQAEQAALRQ-KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2341
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--------ELAETKCAL----------------- 195
ELQ K+ + A Q ++ EL EL++ K +
Sbjct: 2342 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2401
Query: 196 ----QEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDA----------KEVQVKVMEAAE 241
+ EK++Q A + A QE + Q+ A KE V EA
Sbjct: 2402 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2461
Query: 242 ---ELDAWQSGRELCDGQLRGVQYSTESLMEEMA 272
E + Q +EL Q R +Q E + +++A
Sbjct: 2462 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2495
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/250 (24%), Positives = 112/250 (44%), Gaps = 35/250 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
Q L + ++ RQ ++E E+L R ++ ES+ Q +L+ R ++ + + L
Sbjct: 1613 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1672
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q A E R +AE RRL +AE + +RQ+Q E ELQS++++
Sbjct: 1673 Q--ALEELRLQAEEAERRLRQAE------VERARQVQVALETAQRSA---EAELQSKRAS 1721
Query: 172 EQQLAAQLV-TLQNE-------LELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
+ AQL +LQ E E AE + Q E+ +++A + E W + + + L
Sbjct: 1722 FAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL 1781
Query: 222 QVRPHSDAKEVQVKVMEAAE-----ELDAWQSG---------RELCDGQLRGVQYSTESL 267
+++ A++ + EA + E +A + G REL + +L + E
Sbjct: 1782 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1841
Query: 268 MEEMARADRE 277
++ A++E
Sbjct: 1842 AQQRLAAEQE 1851
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 57 QLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER----ERSLLRRRSQAAQPLQ 112
Q++++ R + +EL KL +EAE+ +L R +D ++R E +++ ++ A L
Sbjct: 2362 QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2421
Query: 113 GEAREAARER---------------------------AERVRRRLEEAERHKEYLEQHSR 145
A+EAAR R A R++ E ++ KE ++ +R
Sbjct: 2422 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2481
Query: 146 QLQEQWEELSSQL------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-- 197
+LQE E+++ QL F E + Q+ E A+ + L+ E++ + +E
Sbjct: 2482 RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-VAEMSRAQARAEEDA 2540
Query: 198 -----------EKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAW 246
EKL + L T E + Q + Q H DA+ ++ + E E +
Sbjct: 2541 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAELEREKEKL 2599
Query: 247 QSGRELCDGQLRGVQYST---ESLMEE 270
Q +L QL+ + T E L++E
Sbjct: 2600 QQEAKLL--QLKSEEMQTVQQEQLLQE 2624
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 30/265 (11%)
Query: 19 RRSLPPIVTPASRRLGPRGGRHL----GSVSTAMAATQELLLQLQKDNRDGRQRKQELEK 74
+ L P+ +PA + G + + T + L Q K + +R +E E+
Sbjct: 1427 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1486
Query: 75 LMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAE 134
L AE ++ E++R L +QA + EA+E + E V RR E A
Sbjct: 1487 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1546
Query: 135 RHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCA 194
+Q R +QE+ ++L E + Q Q AA+ L+ E E+ +
Sbjct: 1547 D----AQQQKRSIQEELQQLRQ-----SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1597
Query: 195 LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCD 254
L+ + Q+ + E A+ + A+E + + +A EE + + R++ D
Sbjct: 1598 LEATERQRGGAE-GELQAL------------RARAEEAEAQKRQAQEEAERLR--RQVQD 1642
Query: 255 GQLRGVQYSTE--SLMEEMARADRE 277
R Q E S ++ A A RE
Sbjct: 1643 ESQRKRQAEVELASRVKAEAEAARE 1667
Score = 44.7 bits (104), Expect = 1e-04
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 64/283 (22%)
Query: 45 STAMAATQELLLQLQKD---------NRDGRQRKQELEKLMRGLEAESESLNQRLQDLS- 94
+T + A E LLQ QK+ D Q Q+L + +G + E+ QR ++S
Sbjct: 2459 ATRLKAEAE-LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSA 2517
Query: 95 ERERSLLR---------RRSQAAQPLQGEARE----------AARER------------- 122
E ER LR R + AQ + +A E A +E+
Sbjct: 2518 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2577
Query: 123 ----AERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQ 178
AER+R + E ER KE L+Q ++ LQ + EE+ Q ++QL +
Sbjct: 2578 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-------------QTVQQEQLLQE 2624
Query: 179 LVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVME 238
LQ L+E LQ E+ + + A+ +FQ++ Q ++ Q E
Sbjct: 2625 TQALQQSF-LSEKDSLLQRERFIEQ--EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2681
Query: 239 AAEELDAWQSGRELCDGQLRGVQYSTESLME-EMARADRETRL 280
+ + + R GV+ E L + E R +E L
Sbjct: 2682 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2724
Score = 43.1 bits (100), Expect = 4e-04
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 53/286 (18%)
Query: 32 RLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESES---LNQ 88
RL R G V +LL + Q R++ELE+L R L ES L
Sbjct: 1299 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1358
Query: 89 RLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQ---HSR 145
LQD RRR + Q + +A RE+ + + LEE ERH E +E+ ++
Sbjct: 1359 WLQDA--------RRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1410
Query: 146 QLQEQWEELSSQLFYYGGELQS----------QKSTEQQLA---------AQLVTLQNE- 185
Q ++ QL Y +L+ Q +E + ++L TL ++
Sbjct: 1411 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1470
Query: 186 -------LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS------DAKEV 232
L E + L E++ ++ + AE A ++Q + + + +AKE+
Sbjct: 1471 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKEL 1530
Query: 233 QVKVMEAA---EE--LDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q ++ E EE +DA Q R + + +L+ ++ S+E+ ++ AR
Sbjct: 1531 QQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKAR 1575
Score = 42.4 bits (98), Expect = 6e-04
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 20/186 (10%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-----------------LS 94
++LL + Q + K L + R +E E L Q QD
Sbjct: 2619 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2678
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E+ER L + A+ Q EA E R + E +++ ++ + +E L + +++L+EQ + L
Sbjct: 2679 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLL 2738
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q + S++ T Q+AA TL N + + A E + D L+ +
Sbjct: 2739 EEQ--HRAALAHSEEVTASQVAA-TKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRL 2795
Query: 215 QEQTVV 220
QE ++
Sbjct: 2796 QEAGIL 2801
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 28/199 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGL-EAESESLNQRLQDLSERERSLLRRRSQAAQP 110
+E+ Q + ++K+E E+ R +AE +++ QR +L+E+E L ++ Q A+
Sbjct: 1786 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR--ELAEQE---LEKQRQLAEG 1840
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
+ R AA + R+R E+ E+ ++ LE+ +LQ E +
Sbjct: 1841 T-AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR--------------EAAAATQ 1885
Query: 171 TEQQLAAQLVTLQNELEL-------AETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQV 223
Q+L A+L ++ E+E+ AE + EK +Q A + E+ L+
Sbjct: 1886 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1945
Query: 224 RPHSDAKEVQVKVMEAAEE 242
++ Q+ +AA +
Sbjct: 1946 LAEEAKRQRQLAEEDAARQ 1964
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 38/165 (23%)
Query: 70 QELEKLMRGLEA---ESESLNQRLQDLSERERSL--LRRRSQAAQPLQGEARE---AARE 121
Q E+++R E E++++ L +L + SL LR +++A QP R+ A+E
Sbjct: 1236 QGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQE 1295
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQW--------------EELSSQLFYY------ 161
ER+++R E + E + QL E+W E+L QL YY
Sbjct: 1296 VGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADP 1355
Query: 162 -GGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDAL 205
G LQ + ++Q+ A + LA+++ A++E+ Q+ AL
Sbjct: 1356 LGAWLQDARRRQEQIQA--------MPLADSQ-AVREQLRQEQAL 1391
Score = 29.6 bits (65), Expect = 4.3
Identities = 63/282 (22%), Positives = 105/282 (37%), Gaps = 73/282 (25%)
Query: 52 QELLLQLQKDNRD-GRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLR-------- 102
QE +LQ+D +Q +E + R LEAE + ++L+ +E ER LR
Sbjct: 2477 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ---RQLEMSAEAERLKLRVAEMSRAQ 2533
Query: 103 -RRSQAAQPLQGEARE----------AARER-----------------AERVRRRLEEAE 134
R + AQ + +A E A +E+ AER+R + E E
Sbjct: 2534 ARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELE 2593
Query: 135 RHKEYLEQH----------------------SRQLQEQWEELSSQLFYYGGELQSQKSTE 172
R KE L+Q ++ LQ+ + L LQ ++ E
Sbjct: 2594 REKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL------LQRERFIE 2647
Query: 173 QQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEV 232
Q+ A Q+E+ A+ Q+ + QQ + A +E R +A+E
Sbjct: 2648 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-----RRQHEAEEG 2702
Query: 233 QVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+ E ++L+ + +E + L+EE RA
Sbjct: 2703 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2744
Score = 28.9 bits (63), Expect = 7.4
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 22/113 (19%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQE----LEKLMRGLEA----ESESLNQRLQDLSERERS 99
+ A+ E + Q + +G +RKQE LE+ R E E++ L ++LQ L E+ R+
Sbjct: 2685 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2744
Query: 100 LLRRRSQAA--------------QPLQGEAREAARERAERVRRRLEEAERHKE 138
L + L G A EA E + RR A+R +E
Sbjct: 2745 ALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQE 2797
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 61.6 bits (148), Expect = 1e-09
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 19/249 (7%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQE--------LEKLMRGLEAESESLNQRLQD-LSERE 97
A+ A +EL LQ ++ R RQ + E LE R EAE +S + ++ E
Sbjct: 1512 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1571
Query: 98 RSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQ---LQEQWEEL 154
RSL AQ L+ EA A+++AE R R EEAER E + + + L+ Q EE+
Sbjct: 1572 RSLQEEHVAVAQ-LREEAERRAQQQAEAERAR-EEAERELERWQLKANEALRLRLQAEEV 1629
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-EKLQQDALQTAEAWAI 213
+ Q E + QK E + A+ E + + + A QE EK +Q A TA+
Sbjct: 1630 AQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLA 1688
Query: 214 FQEQTVVLQVRPHSDAKEVQVKVMEAAE---ELDAWQSGRELCDGQLRGVQYSTESLMEE 270
+++ + L+ ++ Q+ E A E A R+ + +L V+ E L+
Sbjct: 1689 AEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLAS 1748
Query: 271 MARADRETR 279
ARA+ E+R
Sbjct: 1749 KARAEEESR 1757
Score = 61.6 bits (148), Expect = 1e-09
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 7/204 (3%)
Query: 42 GSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLL 101
G+ +AA QEL+ +L+ + G Q++Q LE+ + L+ E+ + Q+ Q+L E E + +
Sbjct: 1681 GTAQQRLAAEQELI-RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL-EAELAKV 1738
Query: 102 RRRSQAAQPLQGEAREAARERAERVRRRLE-EAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + + A E +R +E+ ++RLE EA R +E E+ +R L+ EE Q
Sbjct: 1739 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAAR-LRALAEEAKRQRQL 1797
Query: 161 YGGELQSQKS-TEQQLAAQLVTLQNELEL-AETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+ Q++ E+ LA +L + L E + AL+E++ + + L+ FQ +
Sbjct: 1798 AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRR 1857
Query: 219 VVLQVRPH-SDAKEVQVKVMEAAE 241
+ Q H +D +E ++ +A++
Sbjct: 1858 LEEQAAQHKADIEERLAQLRKASD 1881
Score = 56.2 bits (134), Expect = 4e-08
Identities = 72/261 (27%), Positives = 105/261 (40%), Gaps = 32/261 (12%)
Query: 43 SVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQR-LQDLSERERSLL 101
S A A EL L+L GR R + L +AE E+ QR L ER R
Sbjct: 1911 SFEKAAAGKAELELEL------GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1964
Query: 102 RRRSQAAQPLQGEA---REAARERAERVRRRLEEAERHKEYLEQHS-RQLQEQWEELSSQ 157
R Q + + EA R+AA E ER++ ++EEA R +E EQ S RQLQ E +
Sbjct: 1965 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2024
Query: 158 L--------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEE-------KLQQ 202
L F + Q + T QQ + L L+ E E A EE + Q
Sbjct: 2025 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2084
Query: 203 DALQTAEAWAIFQEQTVVLQVRPHSDA------KEVQVKVMEAAEELDAWQSGRELCDGQ 256
Q EA + Q Q R + A KE + + A+ A ++ D +
Sbjct: 2085 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2144
Query: 257 LRGVQYSTESLMEEMARADRE 277
+ + E + + A+ ++E
Sbjct: 2145 MEKHKKFAEQTLRQKAQVEQE 2165
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/274 (23%), Positives = 114/274 (41%), Gaps = 52/274 (18%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLE------AESESLNQRLQDLSERERSL 100
A +E +Q +++ R++ +E E+L + E A++++ ++L+ +E+E +
Sbjct: 2067 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA- 2125
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
RR+QA Q + ++AA E+ ++ E+ R K +EQ L+ Q EE Q
Sbjct: 2126 --RRAQAEQAALRQ-KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2182
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--------ELAETKCAL----------------- 195
ELQ K+ + A Q ++ EL EL++ K +
Sbjct: 2183 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2242
Query: 196 ----QEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDA----------KEVQVKVMEAAE 241
+ EK++Q A + A QE + Q+ A KE V EA
Sbjct: 2243 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2302
Query: 242 ---ELDAWQSGRELCDGQLRGVQYSTESLMEEMA 272
E + Q +EL Q R +Q E + +++A
Sbjct: 2303 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2336
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/250 (24%), Positives = 112/250 (44%), Gaps = 35/250 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
Q L + ++ RQ ++E E+L R ++ ES+ Q +L+ R ++ + + L
Sbjct: 1454 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1513
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q A E R +AE RRL +AE + +RQ+Q E ELQS++++
Sbjct: 1514 Q--ALEELRLQAEEAERRLRQAE------VERARQVQVALETAQRSA---EAELQSKRAS 1562
Query: 172 EQQLAAQLV-TLQNE-------LELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
+ AQL +LQ E E AE + Q E+ +++A + E W + + + L
Sbjct: 1563 FAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL 1622
Query: 222 QVRPHSDAKEVQVKVMEAAE-----ELDAWQSG---------RELCDGQLRGVQYSTESL 267
+++ A++ + EA + E +A + G REL + +L + E
Sbjct: 1623 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1682
Query: 268 MEEMARADRE 277
++ A++E
Sbjct: 1683 AQQRLAAEQE 1692
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 57 QLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER----ERSLLRRRSQAAQPLQ 112
Q++++ R + +EL KL +EAE+ +L R +D ++R E +++ ++ A L
Sbjct: 2203 QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2262
Query: 113 GEAREAARER---------------------------AERVRRRLEEAERHKEYLEQHSR 145
A+EAAR R A R++ E ++ KE ++ +R
Sbjct: 2263 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2322
Query: 146 QLQEQWEELSSQL------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-- 197
+LQE E+++ QL F E + Q+ E A+ + L+ E++ + +E
Sbjct: 2323 RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-VAEMSRAQARAEEDA 2381
Query: 198 -----------EKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAW 246
EKL + L T E + Q + Q H DA+ ++ + E E +
Sbjct: 2382 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAELEREKEKL 2440
Query: 247 QSGRELCDGQLRGVQYST---ESLMEE 270
Q +L QL+ + T E L++E
Sbjct: 2441 QQEAKLL--QLKSEEMQTVQQEQLLQE 2465
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 30/265 (11%)
Query: 19 RRSLPPIVTPASRRLGPRGGRHL----GSVSTAMAATQELLLQLQKDNRDGRQRKQELEK 74
+ L P+ +PA + G + + T + L Q K + +R +E E+
Sbjct: 1268 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1327
Query: 75 LMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAE 134
L AE ++ E++R L +QA + EA+E + E V RR E A
Sbjct: 1328 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1387
Query: 135 RHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCA 194
+Q R +QE+ ++L E + Q Q AA+ L+ E E+ +
Sbjct: 1388 D----AQQQKRSIQEELQQLRQ-----SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1438
Query: 195 LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCD 254
L+ + Q+ + E A+ + A+E + + +A EE + + R++ D
Sbjct: 1439 LEATERQRGGAE-GELQAL------------RARAEEAEAQKRQAQEEAERLR--RQVQD 1483
Query: 255 GQLRGVQYSTE--SLMEEMARADRE 277
R Q E S ++ A A RE
Sbjct: 1484 ESQRKRQAEVELASRVKAEAEAARE 1508
Score = 44.7 bits (104), Expect = 1e-04
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 64/283 (22%)
Query: 45 STAMAATQELLLQLQKD---------NRDGRQRKQELEKLMRGLEAESESLNQRLQDLS- 94
+T + A E LLQ QK+ D Q Q+L + +G + E+ QR ++S
Sbjct: 2300 ATRLKAEAE-LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSA 2358
Query: 95 ERERSLLR---------RRSQAAQPLQGEARE----------AARER------------- 122
E ER LR R + AQ + +A E A +E+
Sbjct: 2359 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2418
Query: 123 ----AERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQ 178
AER+R + E ER KE L+Q ++ LQ + EE+ Q ++QL +
Sbjct: 2419 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-------------QTVQQEQLLQE 2465
Query: 179 LVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVME 238
LQ L+E LQ E+ + + A+ +FQ++ Q ++ Q E
Sbjct: 2466 TQALQQSF-LSEKDSLLQRERFIEQ--EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2522
Query: 239 AAEELDAWQSGRELCDGQLRGVQYSTESLME-EMARADRETRL 280
+ + + R GV+ E L + E R +E L
Sbjct: 2523 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2565
Score = 43.1 bits (100), Expect = 4e-04
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 53/286 (18%)
Query: 32 RLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESES---LNQ 88
RL R G V +LL + Q R++ELE+L R L ES L
Sbjct: 1140 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1199
Query: 89 RLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQ---HSR 145
LQD RRR + Q + +A RE+ + + LEE ERH E +E+ ++
Sbjct: 1200 WLQDA--------RRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1251
Query: 146 QLQEQWEELSSQLFYYGGELQS----------QKSTEQQLA---------AQLVTLQNE- 185
Q ++ QL Y +L+ Q +E + ++L TL ++
Sbjct: 1252 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1311
Query: 186 -------LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS------DAKEV 232
L E + L E++ ++ + AE A ++Q + + + +AKE+
Sbjct: 1312 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKEL 1371
Query: 233 QVKVMEAA---EE--LDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q ++ E EE +DA Q R + + +L+ ++ S+E+ ++ AR
Sbjct: 1372 QQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKAR 1416
Score = 42.4 bits (98), Expect = 6e-04
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 20/186 (10%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-----------------LS 94
++LL + Q + K L + R +E E L Q QD
Sbjct: 2460 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2519
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E+ER L + A+ Q EA E R + E +++ ++ + +E L + +++L+EQ + L
Sbjct: 2520 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLL 2579
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q + S++ T Q+AA TL N + + A E + D L+ +
Sbjct: 2580 EEQ--HRAALAHSEEVTASQVAA-TKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRL 2636
Query: 215 QEQTVV 220
QE ++
Sbjct: 2637 QEAGIL 2642
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 28/199 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGL-EAESESLNQRLQDLSERERSLLRRRSQAAQP 110
+E+ Q + ++K+E E+ R +AE +++ QR +L+E+E L ++ Q A+
Sbjct: 1627 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR--ELAEQE---LEKQRQLAEG 1681
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
+ R AA + R+R E+ E+ ++ LE+ +LQ E +
Sbjct: 1682 T-AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR--------------EAAAATQ 1726
Query: 171 TEQQLAAQLVTLQNELEL-------AETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQV 223
Q+L A+L ++ E+E+ AE + EK +Q A + E+ L+
Sbjct: 1727 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1786
Query: 224 RPHSDAKEVQVKVMEAAEE 242
++ Q+ +AA +
Sbjct: 1787 LAEEAKRQRQLAEEDAARQ 1805
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 38/165 (23%)
Query: 70 QELEKLMRGLEA---ESESLNQRLQDLSERERSL--LRRRSQAAQPLQGEARE---AARE 121
Q E+++R E E++++ L +L + SL LR +++A QP R+ A+E
Sbjct: 1077 QGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQE 1136
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQW--------------EELSSQLFYY------ 161
ER+++R E + E + QL E+W E+L QL YY
Sbjct: 1137 VGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADP 1196
Query: 162 -GGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDAL 205
G LQ + ++Q+ A + LA+++ A++E+ Q+ AL
Sbjct: 1197 LGAWLQDARRRQEQIQA--------MPLADSQ-AVREQLRQEQAL 1232
Score = 29.6 bits (65), Expect = 4.3
Identities = 63/282 (22%), Positives = 105/282 (37%), Gaps = 73/282 (25%)
Query: 52 QELLLQLQKDNRD-GRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLR-------- 102
QE +LQ+D +Q +E + R LEAE + ++L+ +E ER LR
Sbjct: 2318 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ---RQLEMSAEAERLKLRVAEMSRAQ 2374
Query: 103 -RRSQAAQPLQGEARE----------AARER-----------------AERVRRRLEEAE 134
R + AQ + +A E A +E+ AER+R + E E
Sbjct: 2375 ARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELE 2434
Query: 135 RHKEYLEQH----------------------SRQLQEQWEELSSQLFYYGGELQSQKSTE 172
R KE L+Q ++ LQ+ + L LQ ++ E
Sbjct: 2435 REKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL------LQRERFIE 2488
Query: 173 QQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEV 232
Q+ A Q+E+ A+ Q+ + QQ + A +E R +A+E
Sbjct: 2489 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-----RRQHEAEEG 2543
Query: 233 QVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+ E ++L+ + +E + L+EE RA
Sbjct: 2544 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2585
Score = 28.9 bits (63), Expect = 7.4
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 22/113 (19%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQE----LEKLMRGLEA----ESESLNQRLQDLSERERS 99
+ A+ E + Q + +G +RKQE LE+ R E E++ L ++LQ L E+ R+
Sbjct: 2526 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2585
Query: 100 LLRRRSQAA--------------QPLQGEAREAARERAERVRRRLEEAERHKE 138
L + L G A EA E + RR A+R +E
Sbjct: 2586 ALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQE 2638
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 61.6 bits (148), Expect = 1e-09
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 19/249 (7%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQE--------LEKLMRGLEAESESLNQRLQD-LSERE 97
A+ A +EL LQ ++ R RQ + E LE R EAE +S + ++ E
Sbjct: 1520 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1579
Query: 98 RSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQ---LQEQWEEL 154
RSL AQ L+ EA A+++AE R R EEAER E + + + L+ Q EE+
Sbjct: 1580 RSLQEEHVAVAQ-LREEAERRAQQQAEAERAR-EEAERELERWQLKANEALRLRLQAEEV 1637
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-EKLQQDALQTAEAWAI 213
+ Q E + QK E + A+ E + + + A QE EK +Q A TA+
Sbjct: 1638 AQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLA 1696
Query: 214 FQEQTVVLQVRPHSDAKEVQVKVMEAAE---ELDAWQSGRELCDGQLRGVQYSTESLMEE 270
+++ + L+ ++ Q+ E A E A R+ + +L V+ E L+
Sbjct: 1697 AEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLAS 1756
Query: 271 MARADRETR 279
ARA+ E+R
Sbjct: 1757 KARAEEESR 1765
Score = 61.6 bits (148), Expect = 1e-09
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 7/204 (3%)
Query: 42 GSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLL 101
G+ +AA QEL+ +L+ + G Q++Q LE+ + L+ E+ + Q+ Q+L E E + +
Sbjct: 1689 GTAQQRLAAEQELI-RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL-EAELAKV 1746
Query: 102 RRRSQAAQPLQGEAREAARERAERVRRRLE-EAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + + A E +R +E+ ++RLE EA R +E E+ +R L+ EE Q
Sbjct: 1747 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAAR-LRALAEEAKRQRQL 1805
Query: 161 YGGELQSQKS-TEQQLAAQLVTLQNELEL-AETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+ Q++ E+ LA +L + L E + AL+E++ + + L+ FQ +
Sbjct: 1806 AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRR 1865
Query: 219 VVLQVRPH-SDAKEVQVKVMEAAE 241
+ Q H +D +E ++ +A++
Sbjct: 1866 LEEQAAQHKADIEERLAQLRKASD 1889
Score = 56.2 bits (134), Expect = 4e-08
Identities = 72/261 (27%), Positives = 105/261 (40%), Gaps = 32/261 (12%)
Query: 43 SVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQR-LQDLSERERSLL 101
S A A EL L+L GR R + L +AE E+ QR L ER R
Sbjct: 1919 SFEKAAAGKAELELEL------GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 1972
Query: 102 RRRSQAAQPLQGEA---REAARERAERVRRRLEEAERHKEYLEQHS-RQLQEQWEELSSQ 157
R Q + + EA R+AA E ER++ ++EEA R +E EQ S RQLQ E +
Sbjct: 1973 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2032
Query: 158 L--------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEE-------KLQQ 202
L F + Q + T QQ + L L+ E E A EE + Q
Sbjct: 2033 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2092
Query: 203 DALQTAEAWAIFQEQTVVLQVRPHSDA------KEVQVKVMEAAEELDAWQSGRELCDGQ 256
Q EA + Q Q R + A KE + + A+ A ++ D +
Sbjct: 2093 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2152
Query: 257 LRGVQYSTESLMEEMARADRE 277
+ + E + + A+ ++E
Sbjct: 2153 MEKHKKFAEQTLRQKAQVEQE 2173
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/274 (23%), Positives = 114/274 (41%), Gaps = 52/274 (18%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLE------AESESLNQRLQDLSERERSL 100
A +E +Q +++ R++ +E E+L + E A++++ ++L+ +E+E +
Sbjct: 2075 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA- 2133
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
RR+QA Q + ++AA E+ ++ E+ R K +EQ L+ Q EE Q
Sbjct: 2134 --RRAQAEQAALRQ-KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2190
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--------ELAETKCAL----------------- 195
ELQ K+ + A Q ++ EL EL++ K +
Sbjct: 2191 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2250
Query: 196 ----QEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDA----------KEVQVKVMEAAE 241
+ EK++Q A + A QE + Q+ A KE V EA
Sbjct: 2251 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2310
Query: 242 ---ELDAWQSGRELCDGQLRGVQYSTESLMEEMA 272
E + Q +EL Q R +Q E + +++A
Sbjct: 2311 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2344
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/250 (24%), Positives = 112/250 (44%), Gaps = 35/250 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
Q L + ++ RQ ++E E+L R ++ ES+ Q +L+ R ++ + + L
Sbjct: 1462 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1521
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q A E R +AE RRL +AE + +RQ+Q E ELQS++++
Sbjct: 1522 Q--ALEELRLQAEEAERRLRQAE------VERARQVQVALETAQRSA---EAELQSKRAS 1570
Query: 172 EQQLAAQLV-TLQNE-------LELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
+ AQL +LQ E E AE + Q E+ +++A + E W + + + L
Sbjct: 1571 FAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL 1630
Query: 222 QVRPHSDAKEVQVKVMEAAE-----ELDAWQSG---------RELCDGQLRGVQYSTESL 267
+++ A++ + EA + E +A + G REL + +L + E
Sbjct: 1631 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1690
Query: 268 MEEMARADRE 277
++ A++E
Sbjct: 1691 AQQRLAAEQE 1700
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 57 QLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER----ERSLLRRRSQAAQPLQ 112
Q++++ R + +EL KL +EAE+ +L R +D ++R E +++ ++ A L
Sbjct: 2211 QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2270
Query: 113 GEAREAARER---------------------------AERVRRRLEEAERHKEYLEQHSR 145
A+EAAR R A R++ E ++ KE ++ +R
Sbjct: 2271 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2330
Query: 146 QLQEQWEELSSQL------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-- 197
+LQE E+++ QL F E + Q+ E A+ + L+ E++ + +E
Sbjct: 2331 RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-VAEMSRAQARAEEDA 2389
Query: 198 -----------EKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAW 246
EKL + L T E + Q + Q H DA+ ++ + E E +
Sbjct: 2390 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAELEREKEKL 2448
Query: 247 QSGRELCDGQLRGVQYST---ESLMEE 270
Q +L QL+ + T E L++E
Sbjct: 2449 QQEAKLL--QLKSEEMQTVQQEQLLQE 2473
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 30/265 (11%)
Query: 19 RRSLPPIVTPASRRLGPRGGRHL----GSVSTAMAATQELLLQLQKDNRDGRQRKQELEK 74
+ L P+ +PA + G + + T + L Q K + +R +E E+
Sbjct: 1276 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1335
Query: 75 LMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAE 134
L AE ++ E++R L +QA + EA+E + E V RR E A
Sbjct: 1336 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1395
Query: 135 RHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCA 194
+Q R +QE+ ++L E + Q Q AA+ L+ E E+ +
Sbjct: 1396 D----AQQQKRSIQEELQQLRQ-----SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1446
Query: 195 LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCD 254
L+ + Q+ + E A+ + A+E + + +A EE + + R++ D
Sbjct: 1447 LEATERQRGGAE-GELQAL------------RARAEEAEAQKRQAQEEAERLR--RQVQD 1491
Query: 255 GQLRGVQYSTE--SLMEEMARADRE 277
R Q E S ++ A A RE
Sbjct: 1492 ESQRKRQAEVELASRVKAEAEAARE 1516
Score = 44.7 bits (104), Expect = 1e-04
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 64/283 (22%)
Query: 45 STAMAATQELLLQLQKD---------NRDGRQRKQELEKLMRGLEAESESLNQRLQDLS- 94
+T + A E LLQ QK+ D Q Q+L + +G + E+ QR ++S
Sbjct: 2308 ATRLKAEAE-LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSA 2366
Query: 95 ERERSLLR---------RRSQAAQPLQGEARE----------AARER------------- 122
E ER LR R + AQ + +A E A +E+
Sbjct: 2367 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2426
Query: 123 ----AERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQ 178
AER+R + E ER KE L+Q ++ LQ + EE+ Q ++QL +
Sbjct: 2427 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-------------QTVQQEQLLQE 2473
Query: 179 LVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVME 238
LQ L+E LQ E+ + + A+ +FQ++ Q ++ Q E
Sbjct: 2474 TQALQQSF-LSEKDSLLQRERFIEQ--EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2530
Query: 239 AAEELDAWQSGRELCDGQLRGVQYSTESLME-EMARADRETRL 280
+ + + R GV+ E L + E R +E L
Sbjct: 2531 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2573
Score = 43.1 bits (100), Expect = 4e-04
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 53/286 (18%)
Query: 32 RLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESES---LNQ 88
RL R G V +LL + Q R++ELE+L R L ES L
Sbjct: 1148 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1207
Query: 89 RLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQ---HSR 145
LQD RRR + Q + +A RE+ + + LEE ERH E +E+ ++
Sbjct: 1208 WLQDA--------RRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1259
Query: 146 QLQEQWEELSSQLFYYGGELQS----------QKSTEQQLA---------AQLVTLQNE- 185
Q ++ QL Y +L+ Q +E + ++L TL ++
Sbjct: 1260 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1319
Query: 186 -------LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS------DAKEV 232
L E + L E++ ++ + AE A ++Q + + + +AKE+
Sbjct: 1320 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKEL 1379
Query: 233 QVKVMEAA---EE--LDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q ++ E EE +DA Q R + + +L+ ++ S+E+ ++ AR
Sbjct: 1380 QQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKAR 1424
Score = 42.4 bits (98), Expect = 6e-04
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 20/186 (10%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-----------------LS 94
++LL + Q + K L + R +E E L Q QD
Sbjct: 2468 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2527
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E+ER L + A+ Q EA E R + E +++ ++ + +E L + +++L+EQ + L
Sbjct: 2528 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLL 2587
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q + S++ T Q+AA TL N + + A E + D L+ +
Sbjct: 2588 EEQ--HRAALAHSEEVTASQVAA-TKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRL 2644
Query: 215 QEQTVV 220
QE ++
Sbjct: 2645 QEAGIL 2650
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 28/199 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGL-EAESESLNQRLQDLSERERSLLRRRSQAAQP 110
+E+ Q + ++K+E E+ R +AE +++ QR +L+E+E L ++ Q A+
Sbjct: 1635 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR--ELAEQE---LEKQRQLAEG 1689
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
+ R AA + R+R E+ E+ ++ LE+ +LQ E +
Sbjct: 1690 T-AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR--------------EAAAATQ 1734
Query: 171 TEQQLAAQLVTLQNELEL-------AETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQV 223
Q+L A+L ++ E+E+ AE + EK +Q A + E+ L+
Sbjct: 1735 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1794
Query: 224 RPHSDAKEVQVKVMEAAEE 242
++ Q+ +AA +
Sbjct: 1795 LAEEAKRQRQLAEEDAARQ 1813
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 38/165 (23%)
Query: 70 QELEKLMRGLEA---ESESLNQRLQDLSERERSL--LRRRSQAAQPLQGEARE---AARE 121
Q E+++R E E++++ L +L + SL LR +++A QP R+ A+E
Sbjct: 1085 QGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQE 1144
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQW--------------EELSSQLFYY------ 161
ER+++R E + E + QL E+W E+L QL YY
Sbjct: 1145 VGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADP 1204
Query: 162 -GGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDAL 205
G LQ + ++Q+ A + LA+++ A++E+ Q+ AL
Sbjct: 1205 LGAWLQDARRRQEQIQA--------MPLADSQ-AVREQLRQEQAL 1240
Score = 29.6 bits (65), Expect = 4.3
Identities = 63/282 (22%), Positives = 105/282 (37%), Gaps = 73/282 (25%)
Query: 52 QELLLQLQKDNRD-GRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLR-------- 102
QE +LQ+D +Q +E + R LEAE + ++L+ +E ER LR
Sbjct: 2326 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ---RQLEMSAEAERLKLRVAEMSRAQ 2382
Query: 103 -RRSQAAQPLQGEARE----------AARER-----------------AERVRRRLEEAE 134
R + AQ + +A E A +E+ AER+R + E E
Sbjct: 2383 ARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELE 2442
Query: 135 RHKEYLEQH----------------------SRQLQEQWEELSSQLFYYGGELQSQKSTE 172
R KE L+Q ++ LQ+ + L LQ ++ E
Sbjct: 2443 REKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL------LQRERFIE 2496
Query: 173 QQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEV 232
Q+ A Q+E+ A+ Q+ + QQ + A +E R +A+E
Sbjct: 2497 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-----RRQHEAEEG 2551
Query: 233 QVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+ E ++L+ + +E + L+EE RA
Sbjct: 2552 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2593
Score = 28.9 bits (63), Expect = 7.4
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 22/113 (19%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQE----LEKLMRGLEA----ESESLNQRLQDLSERERS 99
+ A+ E + Q + +G +RKQE LE+ R E E++ L ++LQ L E+ R+
Sbjct: 2534 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2593
Query: 100 LLRRRSQAA--------------QPLQGEAREAARERAERVRRRLEEAERHKE 138
L + L G A EA E + RR A+R +E
Sbjct: 2594 ALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQE 2646
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 61.6 bits (148), Expect = 1e-09
Identities = 73/249 (29%), Positives = 115/249 (46%), Gaps = 19/249 (7%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQE--------LEKLMRGLEAESESLNQRLQD-LSERE 97
A+ A +EL LQ ++ R RQ + E LE R EAE +S + ++ E
Sbjct: 1561 ALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLE 1620
Query: 98 RSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQ---LQEQWEEL 154
RSL AQ L+ EA A+++AE R R EEAER E + + + L+ Q EE+
Sbjct: 1621 RSLQEEHVAVAQ-LREEAERRAQQQAEAERAR-EEAERELERWQLKANEALRLRLQAEEV 1678
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-EKLQQDALQTAEAWAI 213
+ Q E + QK E + A+ E + + + A QE EK +Q A TA+
Sbjct: 1679 AQQKSLAQAEAEKQKE-EAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLA 1737
Query: 214 FQEQTVVLQVRPHSDAKEVQVKVMEAAE---ELDAWQSGRELCDGQLRGVQYSTESLMEE 270
+++ + L+ ++ Q+ E A E A R+ + +L V+ E L+
Sbjct: 1738 AEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLAS 1797
Query: 271 MARADRETR 279
ARA+ E+R
Sbjct: 1798 KARAEEESR 1806
Score = 61.6 bits (148), Expect = 1e-09
Identities = 55/204 (26%), Positives = 105/204 (51%), Gaps = 7/204 (3%)
Query: 42 GSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLL 101
G+ +AA QEL+ +L+ + G Q++Q LE+ + L+ E+ + Q+ Q+L E E + +
Sbjct: 1730 GTAQQRLAAEQELI-RLRAETEQGEQQRQLLEEELARLQREAAAATQKRQEL-EAELAKV 1787
Query: 102 RRRSQAAQPLQGEAREAARERAERVRRRLE-EAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + + A E +R +E+ ++RLE EA R +E E+ +R L+ EE Q
Sbjct: 1788 RAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAAR-LRALAEEAKRQRQL 1846
Query: 161 YGGELQSQKS-TEQQLAAQLVTLQNELEL-AETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+ Q++ E+ LA +L + L E + AL+E++ + + L+ FQ +
Sbjct: 1847 AEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRR 1906
Query: 219 VVLQVRPH-SDAKEVQVKVMEAAE 241
+ Q H +D +E ++ +A++
Sbjct: 1907 LEEQAAQHKADIEERLAQLRKASD 1930
Score = 56.2 bits (134), Expect = 4e-08
Identities = 72/261 (27%), Positives = 105/261 (40%), Gaps = 32/261 (12%)
Query: 43 SVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQR-LQDLSERERSLL 101
S A A EL L+L GR R + L +AE E+ QR L ER R
Sbjct: 1960 SFEKAAAGKAELELEL------GRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREA 2013
Query: 102 RRRSQAAQPLQGEA---REAARERAERVRRRLEEAERHKEYLEQHS-RQLQEQWEELSSQ 157
R Q + + EA R+AA E ER++ ++EEA R +E EQ S RQLQ E +
Sbjct: 2014 EERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKR 2073
Query: 158 L--------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEE-------KLQQ 202
L F + Q + T QQ + L L+ E E A EE + Q
Sbjct: 2074 LQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQ 2133
Query: 203 DALQTAEAWAIFQEQTVVLQVRPHSDA------KEVQVKVMEAAEELDAWQSGRELCDGQ 256
Q EA + Q Q R + A KE + + A+ A ++ D +
Sbjct: 2134 SRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAE 2193
Query: 257 LRGVQYSTESLMEEMARADRE 277
+ + E + + A+ ++E
Sbjct: 2194 MEKHKKFAEQTLRQKAQVEQE 2214
Score = 52.0 bits (123), Expect = 8e-07
Identities = 64/274 (23%), Positives = 114/274 (41%), Gaps = 52/274 (18%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLE------AESESLNQRLQDLSERERSL 100
A +E +Q +++ R++ +E E+L + E A++++ ++L+ +E+E +
Sbjct: 2116 AAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAA- 2174
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
RR+QA Q + ++AA E+ ++ E+ R K +EQ L+ Q EE Q
Sbjct: 2175 --RRAQAEQAALRQ-KQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNL 2231
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--------ELAETKCAL----------------- 195
ELQ K+ + A Q ++ EL EL++ K +
Sbjct: 2232 LDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQR 2291
Query: 196 ----QEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDA----------KEVQVKVMEAAE 241
+ EK++Q A + A QE + Q+ A KE V EA
Sbjct: 2292 FLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATR 2351
Query: 242 ---ELDAWQSGRELCDGQLRGVQYSTESLMEEMA 272
E + Q +EL Q R +Q E + +++A
Sbjct: 2352 LKAEAELLQQQKELAQEQARRLQEDKEQMAQQLA 2385
Score = 50.8 bits (120), Expect = 2e-06
Identities = 61/250 (24%), Positives = 112/250 (44%), Gaps = 35/250 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
Q L + ++ RQ ++E E+L R ++ ES+ Q +L+ R ++ + + L
Sbjct: 1503 QALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRAL 1562
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q A E R +AE RRL +AE + +RQ+Q E ELQS++++
Sbjct: 1563 Q--ALEELRLQAEEAERRLRQAE------VERARQVQVALETAQRSA---EAELQSKRAS 1611
Query: 172 EQQLAAQLV-TLQNE-------LELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
+ AQL +LQ E E AE + Q E+ +++A + E W + + + L
Sbjct: 1612 FAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRL 1671
Query: 222 QVRPHSDAKEVQVKVMEAAE-----ELDAWQSG---------RELCDGQLRGVQYSTESL 267
+++ A++ + EA + E +A + G REL + +L + E
Sbjct: 1672 RLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGT 1731
Query: 268 MEEMARADRE 277
++ A++E
Sbjct: 1732 AQQRLAAEQE 1741
Score = 50.1 bits (118), Expect = 3e-06
Identities = 63/267 (23%), Positives = 114/267 (42%), Gaps = 57/267 (21%)
Query: 57 QLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER----ERSLLRRRSQAAQPLQ 112
Q++++ R + +EL KL +EAE+ +L R +D ++R E +++ ++ A L
Sbjct: 2252 QVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLS 2311
Query: 113 GEAREAARER---------------------------AERVRRRLEEAERHKEYLEQHSR 145
A+EAAR R A R++ E ++ KE ++ +R
Sbjct: 2312 VAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQAR 2371
Query: 146 QLQEQWEELSSQL------FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE-- 197
+LQE E+++ QL F E + Q+ E A+ + L+ E++ + +E
Sbjct: 2372 RLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLR-VAEMSRAQARAEEDA 2430
Query: 198 -----------EKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAW 246
EKL + L T E + Q + Q H DA+ ++ + E E +
Sbjct: 2431 QRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDH-DAERLREAIAELEREKEKL 2489
Query: 247 QSGRELCDGQLRGVQYST---ESLMEE 270
Q +L QL+ + T E L++E
Sbjct: 2490 QQEAKLL--QLKSEEMQTVQQEQLLQE 2514
Score = 44.7 bits (104), Expect = 1e-04
Identities = 61/265 (23%), Positives = 106/265 (40%), Gaps = 30/265 (11%)
Query: 19 RRSLPPIVTPASRRLGPRGGRHL----GSVSTAMAATQELLLQLQKDNRDGRQRKQELEK 74
+ L P+ +PA + G + + T + L Q K + +R +E E+
Sbjct: 1317 KAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEER 1376
Query: 75 LMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAE 134
L AE ++ E++R L +QA + EA+E + E V RR E A
Sbjct: 1377 LAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAV 1436
Query: 135 RHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCA 194
+Q R +QE+ ++L E + Q Q AA+ L+ E E+ +
Sbjct: 1437 D----AQQQKRSIQEELQQLRQ-----SSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQ 1487
Query: 195 LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCD 254
L+ + Q+ + E A+ + A+E + + +A EE + + R++ D
Sbjct: 1488 LEATERQRGGAE-GELQAL------------RARAEEAEAQKRQAQEEAERLR--RQVQD 1532
Query: 255 GQLRGVQYSTE--SLMEEMARADRE 277
R Q E S ++ A A RE
Sbjct: 1533 ESQRKRQAEVELASRVKAEAEAARE 1557
Score = 44.7 bits (104), Expect = 1e-04
Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 64/283 (22%)
Query: 45 STAMAATQELLLQLQKD---------NRDGRQRKQELEKLMRGLEAESESLNQRLQDLS- 94
+T + A E LLQ QK+ D Q Q+L + +G + E+ QR ++S
Sbjct: 2349 ATRLKAEAE-LLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSA 2407
Query: 95 ERERSLLR---------RRSQAAQPLQGEARE----------AARER------------- 122
E ER LR R + AQ + +A E A +E+
Sbjct: 2408 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2467
Query: 123 ----AERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQ 178
AER+R + E ER KE L+Q ++ LQ + EE+ Q ++QL +
Sbjct: 2468 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEM-------------QTVQQEQLLQE 2514
Query: 179 LVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVME 238
LQ L+E LQ E+ + + A+ +FQ++ Q ++ Q E
Sbjct: 2515 TQALQQSF-LSEKDSLLQRERFIEQ--EKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2571
Query: 239 AAEELDAWQSGRELCDGQLRGVQYSTESLME-EMARADRETRL 280
+ + + R GV+ E L + E R +E L
Sbjct: 2572 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELL 2614
Score = 43.1 bits (100), Expect = 4e-04
Identities = 70/286 (24%), Positives = 121/286 (42%), Gaps = 53/286 (18%)
Query: 32 RLGPRGGRHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESES---LNQ 88
RL R G V +LL + Q R++ELE+L R L ES L
Sbjct: 1189 RLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGA 1248
Query: 89 RLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQ---HSR 145
LQD RRR + Q + +A RE+ + + LEE ERH E +E+ ++
Sbjct: 1249 WLQDA--------RRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAK 1300
Query: 146 QLQEQWEELSSQLFYYGGELQS----------QKSTEQQLA---------AQLVTLQNE- 185
Q ++ QL Y +L+ Q +E + ++L TL ++
Sbjct: 1301 QYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQY 1360
Query: 186 -------LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS------DAKEV 232
L E + L E++ ++ + AE A ++Q + + + +AKE+
Sbjct: 1361 IKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKEL 1420
Query: 233 QVKVMEAA---EE--LDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q ++ E EE +DA Q R + + +L+ ++ S+E+ ++ AR
Sbjct: 1421 QQRMQEEVVRREEAAVDAQQQKRSIQE-ELQQLRQSSEAEIQAKAR 1465
Score = 42.4 bits (98), Expect = 6e-04
Identities = 44/186 (23%), Positives = 78/186 (41%), Gaps = 20/186 (10%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-----------------LS 94
++LL + Q + K L + R +E E L Q QD
Sbjct: 2509 EQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQM 2568
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E+ER L + A+ Q EA E R + E +++ ++ + +E L + +++L+EQ + L
Sbjct: 2569 EQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLL 2628
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q + S++ T Q+AA TL N + + A E + D L+ +
Sbjct: 2629 EEQ--HRAALAHSEEVTASQVAA-TKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRL 2685
Query: 215 QEQTVV 220
QE ++
Sbjct: 2686 QEAGIL 2691
Score = 40.0 bits (92), Expect = 0.003
Identities = 45/199 (22%), Positives = 88/199 (44%), Gaps = 28/199 (14%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGL-EAESESLNQRLQDLSERERSLLRRRSQAAQP 110
+E+ Q + ++K+E E+ R +AE +++ QR +L+E+E L ++ Q A+
Sbjct: 1676 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQR--ELAEQE---LEKQRQLAEG 1730
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
+ R AA + R+R E+ E+ ++ LE+ +LQ E +
Sbjct: 1731 T-AQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQR--------------EAAAATQ 1775
Query: 171 TEQQLAAQLVTLQNELEL-------AETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQV 223
Q+L A+L ++ E+E+ AE + EK +Q A + E+ L+
Sbjct: 1776 KRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRA 1835
Query: 224 RPHSDAKEVQVKVMEAAEE 242
++ Q+ +AA +
Sbjct: 1836 LAEEAKRQRQLAEEDAARQ 1854
Score = 38.1 bits (87), Expect = 0.012
Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 38/165 (23%)
Query: 70 QELEKLMRGLEA---ESESLNQRLQDLSERERSL--LRRRSQAAQPLQGEARE---AARE 121
Q E+++R E E++++ L +L + SL LR +++A QP R+ A+E
Sbjct: 1126 QGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQE 1185
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQW--------------EELSSQLFYY------ 161
ER+++R E + E + QL E+W E+L QL YY
Sbjct: 1186 VGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADP 1245
Query: 162 -GGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDAL 205
G LQ + ++Q+ A + LA+++ A++E+ Q+ AL
Sbjct: 1246 LGAWLQDARRRQEQIQA--------MPLADSQ-AVREQLRQEQAL 1281
Score = 29.6 bits (65), Expect = 4.3
Identities = 63/282 (22%), Positives = 105/282 (37%), Gaps = 73/282 (25%)
Query: 52 QELLLQLQKDNRD-GRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLR-------- 102
QE +LQ+D +Q +E + R LEAE + ++L+ +E ER LR
Sbjct: 2367 QEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQ---RQLEMSAEAERLKLRVAEMSRAQ 2423
Query: 103 -RRSQAAQPLQGEARE----------AARER-----------------AERVRRRLEEAE 134
R + AQ + +A E A +E+ AER+R + E E
Sbjct: 2424 ARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELE 2483
Query: 135 RHKEYLEQH----------------------SRQLQEQWEELSSQLFYYGGELQSQKSTE 172
R KE L+Q ++ LQ+ + L LQ ++ E
Sbjct: 2484 REKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSL------LQRERFIE 2537
Query: 173 QQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEV 232
Q+ A Q+E+ A+ Q+ + QQ + A +E R +A+E
Sbjct: 2538 QEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEAR-----RRQHEAEEG 2592
Query: 233 QVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+ E ++L+ + +E + L+EE RA
Sbjct: 2593 VRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2634
Score = 28.9 bits (63), Expect = 7.4
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 22/113 (19%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQE----LEKLMRGLEA----ESESLNQRLQDLSERERS 99
+ A+ E + Q + +G +RKQE LE+ R E E++ L ++LQ L E+ R+
Sbjct: 2575 LVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRA 2634
Query: 100 LLRRRSQAA--------------QPLQGEAREAARERAERVRRRLEEAERHKE 138
L + L G A EA E + RR A+R +E
Sbjct: 2635 ALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQE 2687
>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
Length = 1670
Score = 60.8 bits (146), Expect = 2e-09
Identities = 66/241 (27%), Positives = 111/241 (46%), Gaps = 31/241 (12%)
Query: 52 QELLLQLQKD-NRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQP 110
Q L+ Q Q++ R ++ K+E E+ R L+ + L+ E++R L R+R + +
Sbjct: 383 QALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKRLEKQRELERQREEERRK 442
Query: 111 LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS 170
E REAA++ ER RR E R +E L Q +R+ QE+ L+S+ EL++
Sbjct: 443 -DIERREAAKQELERQRRLEWERIRRQELLNQKNRE-QEEIVRLNSKKKNLHLELEALNG 500
Query: 171 TEQQLAAQL-------VTLQNELELAETKCALQ--EEKLQQDALQTAEAWAIFQEQTVVL 221
QQ++ +L T + ELE+ + +C L+ E K Q LQ + Q ++
Sbjct: 501 KHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQLQQELQ--------EYQNKLI 552
Query: 222 QVRPHSDAKEVQVKVMEAAEELDAWQS--------GRELCD---GQLRGVQYSTESLMEE 270
+ P ++K M+ + D+ S ELC QL ++ T S + E
Sbjct: 553 YLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLDALEKETASKLSE 612
Query: 271 M 271
M
Sbjct: 613 M 613
Score = 32.3 bits (72), Expect = 0.67
Identities = 33/167 (19%), Positives = 70/167 (41%), Gaps = 6/167 (3%)
Query: 120 RERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQL 179
+ +A R +E +R + +EQ R+ + + ++ + ELQ Q+ +Q +
Sbjct: 366 KRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQLELEKR 425
Query: 180 VTLQNELELAETKCALQEEKLQQDALQTAE-----AWAIFQEQTVVLQV-RPHSDAKEVQ 233
+ Q ELE + ++ + ++ A Q E W + Q ++ Q R + +
Sbjct: 426 LEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEEIVRLN 485
Query: 234 VKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRL 280
K EL+A + G+L+ V+ ++ E+ D++ L
Sbjct: 486 SKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDL 532
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 59.7 bits (143), Expect = 4e-09
Identities = 57/211 (27%), Positives = 101/211 (47%), Gaps = 21/211 (9%)
Query: 49 AATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAA 108
AA +E LL+LQ+ + ++ QELE L++ + ++E L LQ+ ER RS R QA
Sbjct: 341 AAKEEELLRLQQLQEEKERKLQELE-LLQEAQRQAERL---LQEEEERRRSQHRELQQA- 395
Query: 109 QPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQ 168
L+G+ REA + RA ++ +E E Q ++L+E + L L + +
Sbjct: 396 --LEGQLREAEQARAS-MQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDE 452
Query: 169 KST----------EQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+S E++ QL+ L+ E E + ++E+LQQ+ Q + + Q+Q
Sbjct: 453 ESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQL 512
Query: 219 VVL---QVRPHSDAKEVQVKVMEAAEELDAW 246
+ + R D + Q K+ +A+ + W
Sbjct: 513 EEVRQNRQRADEDVEAAQRKLRQASTNVKHW 543
Score = 47.4 bits (111), Expect = 2e-05
Identities = 56/240 (23%), Positives = 102/240 (42%), Gaps = 34/240 (14%)
Query: 62 NRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARE 121
+RDG++ ++ R E + QR Q+ + + +R +++ L + ++ RE
Sbjct: 273 DRDGKRCMFCVKTANRTYEMSASDTRQR-QEWTAAIQMAIRLQAEGKTSLHKDLKQKRRE 331
Query: 122 RAERVRRR---------------------LEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
+ E+ RR L+E E +E Q R LQE+ E SQ
Sbjct: 332 QREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRE 391
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVV 220
L+ Q +Q A ++Q E+EL E + A Q +++++ E ++ +
Sbjct: 392 LQQALEGQLREAEQARA---SMQAEMELKEEEAARQRQRIKE-----LEEMQQRLQEALQ 443
Query: 221 LQVRPHSDAKEV---QVKVMEAAEE-LDAWQSGRELCDGQLRGVQYSTESLMEEMARADR 276
L+V+ D + V Q +++E EE L +E + + Q E L +EMA+ R
Sbjct: 444 LEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSR 503
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 59.3 bits (142), Expect = 5e-09
Identities = 60/246 (24%), Positives = 105/246 (42%), Gaps = 34/246 (13%)
Query: 66 RQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGE----------- 114
+Q K++LE+ + L+A+SE + LQ L ++ + L L+G+
Sbjct: 1401 QQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQ 1460
Query: 115 -----AREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEE-------LSSQLFYYG 162
A E A+R + + E+ +R K+ L + L++Q EE + ++
Sbjct: 1461 RRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLE 1520
Query: 163 GELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDA--LQTAEAWAIFQEQTVV 220
ELQ S E + A L ++ +L E K QEE+L + A +Q E + E +
Sbjct: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580
Query: 221 LQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRL 280
+ HS K ME+ +E + R+ C +L+ ++ E E+ + RE R
Sbjct: 1581 RMRQTHS-------KEMESRDE--EVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE 1631
Query: 281 FGGPRA 286
G A
Sbjct: 1632 LEGKLA 1637
Score = 44.3 bits (103), Expect = 2e-04
Identities = 57/247 (23%), Positives = 112/247 (45%), Gaps = 29/247 (11%)
Query: 47 AMAATQELLLQLQKDN----RDGRQRKQELE----------KLMRGLEAESESLNQRLQD 92
A+ A +L+L K++ R+ Q K +LE K + +E E E L+ ++ D
Sbjct: 1663 ALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD 1722
Query: 93 LSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEE-AERHKEYLEQHSRQLQEQW 151
+++ + +L + S+ LQ E E ++ RLEE E E +++H + +
Sbjct: 1723 IAKAKTALEEQLSR----LQREKNE--------IQNRLEEDQEDMNELMKKHKAAVAQAS 1770
Query: 152 EELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDA-LQTAEA 210
+L +Q+ +L+ +Q+L +L LQ+++E E + +Q+A ++ E
Sbjct: 1771 RDL-AQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELET 1829
Query: 211 WAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEE 270
F+ V S KE K+ E ++ A ++ + + +L+ T+ M E
Sbjct: 1830 RLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGE 1889
Query: 271 MARADRE 277
+AR + E
Sbjct: 1890 LARKEAE 1896
Score = 39.3 bits (90), Expect = 0.005
Identities = 55/273 (20%), Positives = 109/273 (39%), Gaps = 48/273 (17%)
Query: 49 AATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQ-------------RLQDLSE 95
A Q++ Q KD + K++L L ++ + E L++ RL+ E
Sbjct: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580
Query: 96 RERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELS 155
R R + ++ EAR++ +++ +++ +LEE K+ + + R+L+ + LS
Sbjct: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLS 1640
Query: 156 SQLFYYGGELQSQ-----KSTEQQLA----------------AQLVTLQNELELAETKCA 194
Q+ E + + K T+ LA ++ L+N+LE +E CA
Sbjct: 1641 DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCA 1700
Query: 195 ----------LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELD 244
++ E L A+A +EQ LQ + E+Q ++ E E+++
Sbjct: 1701 AAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQ----REKNEIQNRLEEDQEDMN 1756
Query: 245 AWQSGRELCDGQLRGVQYSTESLMEEMARADRE 277
+ Q L ++ A++E
Sbjct: 1757 ELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1789
Score = 37.4 bits (85), Expect = 0.021
Identities = 59/247 (23%), Positives = 109/247 (44%), Gaps = 22/247 (8%)
Query: 44 VSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAE----SESLNQRLQDLSERERS 99
V A + Q+ L Q++ + + KQ++ + R LE + S+ +N+R + +R R
Sbjct: 1597 VEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRK 1656
Query: 100 LLRRRSQA---AQPLQGEAREAARERAE--RVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
L+R AQ + + +A + E +++ +LEE+E + + ++ + E+L
Sbjct: 1657 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1716
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q+ ++ K+ L QL LQ E E + L+E++ + L A+
Sbjct: 1717 HLQI----DDIAKAKTA---LEEQLSRLQREKN--EIQNRLEEDQEDMNELMKKHKAAVA 1767
Query: 215 QEQTVVLQVRP-HSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q + Q+ + +E + E E+L A QS E + + V S S E R
Sbjct: 1768 QASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM--VDKSLVSRQEAKIR 1825
Query: 274 ADRETRL 280
+ ETRL
Sbjct: 1826 -ELETRL 1831
Score = 35.8 bits (81), Expect = 0.061
Identities = 39/168 (23%), Positives = 72/168 (42%), Gaps = 17/168 (10%)
Query: 53 ELLLQLQKDNRDGRQRKQEL----------EKLMRGLEAESESLNQRLQDLSERERSLLR 102
EL +L + G Q L EK M+ L+ + ++L ++++ + E ++
Sbjct: 1293 ELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVM---EMEVME 1349
Query: 103 RRSQAAQPLQGEARE--AARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R A + GE + A E + R + E + K+ L+Q E ++ QL
Sbjct: 1350 ARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER 1409
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--ELAETKCALQEEKLQQDALQ 206
G+LQ+ Q+ QL L EL +TK L+ ++++ L+
Sbjct: 1410 RLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457
Score = 34.3 bits (77), Expect = 0.18
Identities = 38/169 (22%), Positives = 74/169 (43%), Gaps = 22/169 (13%)
Query: 56 LQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER--ERSLLRRRSQAAQP--- 110
L+ Q+D + R + RG A +++QDL+ R ++++ + + P
Sbjct: 1180 LEEQRDEQTSRNLTL-FQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWK 1238
Query: 111 ------------LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQL 158
L E E +++R +LE+AE+ + L +S +L+ + EL+S+L
Sbjct: 1239 LFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 1298
Query: 159 FYYGGELQSQKSTEQQLAAQLV-TLQNELELAETKCALQEEKLQQDALQ 206
E + +S Q L A+ L+ E E+ E + K Q + ++
Sbjct: 1299 ---TDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVME 1344
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 59.3 bits (142), Expect = 5e-09
Identities = 60/246 (24%), Positives = 105/246 (42%), Gaps = 34/246 (13%)
Query: 66 RQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGE----------- 114
+Q K++LE+ + L+A+SE + LQ L ++ + L L+G+
Sbjct: 1401 QQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQ 1460
Query: 115 -----AREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEE-------LSSQLFYYG 162
A E A+R + + E+ +R K+ L + L++Q EE + ++
Sbjct: 1461 RRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLE 1520
Query: 163 GELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDA--LQTAEAWAIFQEQTVV 220
ELQ S E + A L ++ +L E K QEE+L + A +Q E + E +
Sbjct: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580
Query: 221 LQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRL 280
+ HS K ME+ +E + R+ C +L+ ++ E E+ + RE R
Sbjct: 1581 RMRQTHS-------KEMESRDE--EVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE 1631
Query: 281 FGGPRA 286
G A
Sbjct: 1632 LEGKLA 1637
Score = 44.3 bits (103), Expect = 2e-04
Identities = 57/247 (23%), Positives = 112/247 (45%), Gaps = 29/247 (11%)
Query: 47 AMAATQELLLQLQKDN----RDGRQRKQELE----------KLMRGLEAESESLNQRLQD 92
A+ A +L+L K++ R+ Q K +LE K + +E E E L+ ++ D
Sbjct: 1663 ALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD 1722
Query: 93 LSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEE-AERHKEYLEQHSRQLQEQW 151
+++ + +L + S+ LQ E E ++ RLEE E E +++H + +
Sbjct: 1723 IAKAKTALEEQLSR----LQREKNE--------IQNRLEEDQEDMNELMKKHKAAVAQAS 1770
Query: 152 EELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDA-LQTAEA 210
+L +Q+ +L+ +Q+L +L LQ+++E E + +Q+A ++ E
Sbjct: 1771 RDL-AQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELET 1829
Query: 211 WAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEE 270
F+ V S KE K+ E ++ A ++ + + +L+ T+ M E
Sbjct: 1830 RLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGE 1889
Query: 271 MARADRE 277
+AR + E
Sbjct: 1890 LARKEAE 1896
Score = 39.3 bits (90), Expect = 0.005
Identities = 55/273 (20%), Positives = 109/273 (39%), Gaps = 48/273 (17%)
Query: 49 AATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQ-------------RLQDLSE 95
A Q++ Q KD + K++L L ++ + E L++ RL+ E
Sbjct: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580
Query: 96 RERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELS 155
R R + ++ EAR++ +++ +++ +LEE K+ + + R+L+ + LS
Sbjct: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLS 1640
Query: 156 SQLFYYGGELQSQ-----KSTEQQLA----------------AQLVTLQNELELAETKCA 194
Q+ E + + K T+ LA ++ L+N+LE +E CA
Sbjct: 1641 DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCA 1700
Query: 195 ----------LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELD 244
++ E L A+A +EQ LQ + E+Q ++ E E+++
Sbjct: 1701 AAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQ----REKNEIQNRLEEDQEDMN 1756
Query: 245 AWQSGRELCDGQLRGVQYSTESLMEEMARADRE 277
+ Q L ++ A++E
Sbjct: 1757 ELMKKHKAAVAQASRDLAQINDLQAQLEEANKE 1789
Score = 37.4 bits (85), Expect = 0.021
Identities = 59/247 (23%), Positives = 109/247 (44%), Gaps = 22/247 (8%)
Query: 44 VSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAE----SESLNQRLQDLSERERS 99
V A + Q+ L Q++ + + KQ++ + R LE + S+ +N+R + +R R
Sbjct: 1597 VEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRK 1656
Query: 100 LLRRRSQA---AQPLQGEAREAARERAE--RVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
L+R AQ + + +A + E +++ +LEE+E + + ++ + E+L
Sbjct: 1657 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1716
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
Q+ ++ K+ L QL LQ E E + L+E++ + L A+
Sbjct: 1717 HLQI----DDIAKAKTA---LEEQLSRLQREKN--EIQNRLEEDQEDMNELMKKHKAAVA 1767
Query: 215 QEQTVVLQVRP-HSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
Q + Q+ + +E + E E+L A QS E + + V S S E R
Sbjct: 1768 QASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM--VDKSLVSRQEAKIR 1825
Query: 274 ADRETRL 280
+ ETRL
Sbjct: 1826 -ELETRL 1831
Score = 35.8 bits (81), Expect = 0.061
Identities = 39/168 (23%), Positives = 72/168 (42%), Gaps = 17/168 (10%)
Query: 53 ELLLQLQKDNRDGRQRKQEL----------EKLMRGLEAESESLNQRLQDLSERERSLLR 102
EL +L + G Q L EK M+ L+ + ++L ++++ + E ++
Sbjct: 1293 ELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVM---EMEVME 1349
Query: 103 RRSQAAQPLQGEARE--AARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R A + GE + A E + R + E + K+ L+Q E ++ QL
Sbjct: 1350 ARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLER 1409
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL--ELAETKCALQEEKLQQDALQ 206
G+LQ+ Q+ QL L EL +TK L+ ++++ L+
Sbjct: 1410 RLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELE 1457
Score = 34.3 bits (77), Expect = 0.18
Identities = 38/169 (22%), Positives = 74/169 (43%), Gaps = 22/169 (13%)
Query: 56 LQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSER--ERSLLRRRSQAAQP--- 110
L+ Q+D + R + RG A +++QDL+ R ++++ + + P
Sbjct: 1180 LEEQRDEQTSRNLTL-FQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWK 1238
Query: 111 ------------LQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQL 158
L E E +++R +LE+AE+ + L +S +L+ + EL+S+L
Sbjct: 1239 LFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 1298
Query: 159 FYYGGELQSQKSTEQQLAAQLV-TLQNELELAETKCALQEEKLQQDALQ 206
E + +S Q L A+ L+ E E+ E + K Q + ++
Sbjct: 1299 ---TDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVME 1344
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 58.5 bits (140), Expect = 9e-09
Identities = 59/247 (23%), Positives = 107/247 (43%), Gaps = 11/247 (4%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
QEL+LQ ++ QR ++ + L LE SL +R ++L+ + + + R + P
Sbjct: 1658 QELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGP- 1716
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
+A R E ++ L + E+ E ++H +LQE ++L QL ++
Sbjct: 1717 ----SKAQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLL 1772
Query: 172 EQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKE 231
Q ++V LQ +L+ A + L+E+ LQ + A A ++ LQ + ++
Sbjct: 1773 LSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQ----QEQQQ 1828
Query: 232 VQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIRR 291
Q + E+ DA Q E L+ + E+ R + E + G R +
Sbjct: 1829 AQGQEERVKEKADALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEG--RRVQALE 1886
Query: 292 CVLGALQ 298
VLG L+
Sbjct: 1887 EVLGDLR 1893
Score = 58.5 bits (140), Expect = 9e-09
Identities = 56/234 (23%), Positives = 109/234 (46%), Gaps = 14/234 (5%)
Query: 50 ATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQ 109
A +E+L L+ ++R+ + L++ E E + LQD + +++L+ R Q +
Sbjct: 1884 ALEEVLGDLRAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELE 1943
Query: 110 PLQGEAR------EAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGG 163
L+ E++ EAAR RAE ++ L +A + EQH + E L +
Sbjct: 1944 ALRAESQSSRHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQA 2003
Query: 164 ELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQV 223
L + ++ +QL L + E++ + + ++LQQ Q E QE+ +L+
Sbjct: 2004 SLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLE- 2062
Query: 224 RPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRE 277
S A+ VQ +++ + L G+E + ++RG+ S L +A+ ++E
Sbjct: 2063 --KSLAQRVQENMIQEKQNL-----GQEREEEEIRGLHQSVRELQLTLAQKEQE 2109
Score = 51.6 bits (122), Expect = 1e-06
Identities = 53/236 (22%), Positives = 111/236 (47%), Gaps = 13/236 (5%)
Query: 54 LLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD----LSERERSL--LRRRSQA 107
+L +K+ ++ EL++L LE + + L++++ + LS+RE+ + L+++ Q
Sbjct: 1730 ILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQEIVVLQQQLQE 1789
Query: 108 AQPLQGEAREAA-RERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQ 166
A+ QGE +E + + + + +R L + ++ E L+Q +Q Q Q E + + G L+
Sbjct: 1790 ARE-QGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKEKADALQGALE 1848
Query: 167 SQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPH 226
T ++ +L + + E + A++ ++Q + A +EQ L
Sbjct: 1849 QAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEEVLGDLRAESREQEKALLALQQ 1908
Query: 227 SDAKEVQVKVMEAAEELDAWQSGRELC---DGQLRGVQYSTESL--MEEMARADRE 277
A++ Q +E D+W + + D +L ++ ++S EE ARA E
Sbjct: 1909 QCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSSRHQEEAARARAE 1964
Score = 51.2 bits (121), Expect = 1e-06
Identities = 59/230 (25%), Positives = 95/230 (41%), Gaps = 38/230 (16%)
Query: 44 VSTAMAATQELLLQLQKDNR-------DGRQRKQELEKLMRGLEAESESLNQRLQDLSER 96
V+ A+A ++ + +L D R +L L L + LNQ+L L E
Sbjct: 566 VTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEEE 625
Query: 97 ERSLLRRRSQAAQPLQG---------EAREAARERAERVRRRLEEAERHKEYLEQHSRQL 147
+S+ R A Q + REA E+ + +L++AE L+ R +
Sbjct: 626 NQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDI 685
Query: 148 QEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQT 207
QE+ EE+ +L +S QQ AA +LE + QEE L + A+Q
Sbjct: 686 QEEKEEIQKKL---------SESRHQQEAA-----TTQLEQLHQEAKRQEEVLAR-AVQE 730
Query: 208 AEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQL 257
EA + L+VR + ++ Q + AE+L S +EL + L
Sbjct: 731 KEA---LVREKAALEVRLQAVERDRQ----DLAEQLQGLSSAKELLESSL 773
Score = 49.7 bits (117), Expect = 4e-06
Identities = 57/199 (28%), Positives = 95/199 (47%), Gaps = 33/199 (16%)
Query: 53 ELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERS-LLRRRSQAAQPL 111
E LLQ QK+ D Q+LE+L + + ++Q L E+E + +L+ + Q AQ
Sbjct: 932 ETLLQTQKELADA---SQQLERLRQDM---------KVQKLKEQETTGILQTQLQEAQR- 978
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
E +EAAR+ + + EE+ L Q LQ+Q E+L SQL + SQ+
Sbjct: 979 --ELKEAARQHRDDLAALQEESSS----LLQDKMDLQKQVEDLKSQLV---AQDDSQRLV 1029
Query: 172 EQQLAAQL------VTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRP 225
EQ++ +L +Q ELE + L + +Q L EA +I Q++ L+
Sbjct: 1030 EQEVQEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALR--- 1086
Query: 226 HSDAKEVQVKVMEAAEELD 244
D +E Q + E + +++
Sbjct: 1087 -QDMQEAQGEQKELSAQME 1104
Score = 48.9 bits (115), Expect = 7e-06
Identities = 55/207 (26%), Positives = 93/207 (44%), Gaps = 22/207 (10%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
+E +LQ D RD ++ K+E++K + + E+ +L+ L + + ++A Q
Sbjct: 672 EEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLARAVQEK 731
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKS- 170
+ RE A + RL+ ER ++ L + + L E L S LF E Q Q S
Sbjct: 732 EALVREKA-----ALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLF----EAQQQNSV 782
Query: 171 ---TEQQLAAQL--VTLQNELELAETKC---ALQEEKLQQDALQTAEAWAIF---QEQTV 219
T+ QL Q+ VT E+ E +C L E+ Q + + A A + QE
Sbjct: 783 IEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKT 842
Query: 220 VLQVRPHSDAKEVQVKVMEAAEELDAW 246
L+ + + KEV ++ E E+ +W
Sbjct: 843 ALEQQKAAHEKEVN-QLREKWEKERSW 868
Score = 46.2 bits (108), Expect = 4e-05
Identities = 59/261 (22%), Positives = 119/261 (45%), Gaps = 48/261 (18%)
Query: 49 AATQELLLQLQKDNRDGRQRKQELEKLMRGLEA---ESESLNQRLQDLSERERSLLRRRS 105
AA + L +++D +D ++ Q L LE+ E++ N ++ + ++ +
Sbjct: 739 AALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNSVIEVTKGQLEVQIQTVT 798
Query: 106 QAAQPLQGEAR------EAARERAERVR----RRLEEAERH-KEYLEQHS-------RQL 147
QA + +QGE R + R +AE+ R R+L +AE+ K LEQ QL
Sbjct: 799 QAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGKTALEQQKAAHEKEVNQL 858
Query: 148 QEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQT 207
+E+WE + + +Q+LA L +L E E E + L+E++ + +A+Q
Sbjct: 859 REKWE-------------KERSWHQQELAKALESL--EREKMELEMRLKEQQTEMEAIQA 903
Query: 208 AEAWAIFQEQTVVLQVRPHSDAKEV---------QVKVMEAAEELDAWQSGRELCDGQLR 258
Q ++ + Q++ ++ + V Q ++ +A+++L+ + ++ Q
Sbjct: 904 QREEERTQAESALCQMQLETEKERVSLLETLLQTQKELADASQQLERLRQDMKV---QKL 960
Query: 259 GVQYSTESLMEEMARADRETR 279
Q +T L ++ A RE +
Sbjct: 961 KEQETTGILQTQLQEAQRELK 981
Score = 44.7 bits (104), Expect = 1e-04
Identities = 50/249 (20%), Positives = 107/249 (42%), Gaps = 19/249 (7%)
Query: 43 SVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDL------SER 96
+V++A+ + L + Q+ R + Q+LE+ + EAE ++ LQDL ++
Sbjct: 1240 AVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTEAEKSQVHTELQDLQRQLSQNQE 1299
Query: 97 ERSLLRRRSQAAQPLQGEAREAARERAERVRR---RLEEAERHKEYLEQHSRQLQEQWEE 153
E+S + + + E E R+RR + EA+ +E L+ L Q E
Sbjct: 1300 EKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEH 1359
Query: 154 LSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQ----QDALQTAE 209
L + + E ++Q S L L T ++ L+L + + E+ Q Q L+ A+
Sbjct: 1360 LQAAVV----EARAQASAAGILEEDLRTARSALKLKNEEVESERERAQALQEQGELKVAQ 1415
Query: 210 AWAIFQEQTVVLQ--VRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESL 267
A+ + ++ Q + + ++ ++ E ++ + ++ EL L+ +
Sbjct: 1416 GKALQENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQ 1475
Query: 268 MEEMARADR 276
E++ ++
Sbjct: 1476 QEQIQELEK 1484
Score = 43.5 bits (101), Expect = 3e-04
Identities = 60/308 (19%), Positives = 120/308 (38%), Gaps = 73/308 (23%)
Query: 39 RHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRL----QDLS 94
R S++ ++ ++ LL LQ+ + +Q L + M+ + E + L+ ++ Q++
Sbjct: 1052 REKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKELSAQMELLRQEVK 1111
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E+E L + +Q + L EA+ +++R L E L+ R + Q E L
Sbjct: 1112 EKEADFLAQEAQLLEEL-----EASHITEQQLRASLWAQEAKAAQLQLRLRSTESQLEAL 1166
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELA-----ETK----------------- 192
+++ Q + Q AQL +L + L+ A E++
Sbjct: 1167 AAE---------QQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVWGLE 1217
Query: 193 ----------------CALQEE-------KLQQDALQTAEAWAIFQEQTVVLQVR----- 224
AL E KL QD +T + + ++Q L+ R
Sbjct: 1218 PDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLTDTE 1277
Query: 225 -----PHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETR 279
H++ +++Q ++ + EE W+ + + +L + + SL + RA+ +
Sbjct: 1278 AEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESELMELHETMASLQSRLRRAELQRM 1337
Query: 280 LFGGPRAL 287
G R L
Sbjct: 1338 EAQGEREL 1345
Score = 40.8 bits (94), Expect = 0.002
Identities = 52/194 (26%), Positives = 85/194 (43%), Gaps = 26/194 (13%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLN--QRLQDLSERERSLLRRRSQAAQ 109
QE L + Q+ NR ++ ++E L L + + L Q + ++E S LR+ Q AQ
Sbjct: 1034 QEKLRETQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQELSALRQDMQEAQ 1093
Query: 110 PLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQK 169
GE +E + A+ R E E+ ++L Q ++ L+ EL++
Sbjct: 1094 ---GEQKELS---AQMELLRQEVKEKEADFLAQEAQLLE---------------ELEASH 1132
Query: 170 STEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDA 229
TEQQL A L E + A+ + L+ + Q +AL AE Q Q +S
Sbjct: 1133 ITEQQLRASL--WAQEAKAAQLQLRLRSTESQLEAL-AAEQQPGNQAQAQAQLASLYSAL 1189
Query: 230 KEVQVKVMEAAEEL 243
++ V E+ EL
Sbjct: 1190 QQALGSVCESRPEL 1203
Score = 40.0 bits (92), Expect = 0.003
Identities = 60/257 (23%), Positives = 108/257 (42%), Gaps = 32/257 (12%)
Query: 41 LGSVSTAMAATQELLLQLQKD--NRDGRQRK--QELEKLMRGLEAE-----SESLNQRLQ 91
L ++++ QE+ + LQ RD Q++ ELE R LE E + L
Sbjct: 2180 LAQTKASVSSLQEVAMFLQASVLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELG 2239
Query: 92 DLSERERSLLRRRSQAAQPL-QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQ 150
E+ L A+P G +++ R+R E +++ + E + L++H+ QL+
Sbjct: 2240 SRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDRSRLQRHNVQLRST 2299
Query: 151 WEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEA 210
E++ + + + E AAQ +L E+ A Q++ Q A+
Sbjct: 2300 LEQVERE--------RRKLKREAMRAAQAGSL--EISKATASSPTQQDGRGQKN-SDAKC 2348
Query: 211 WAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEE 270
A Q++ V+LQ + + K+ Q + +A Q+ REL G+ +S +
Sbjct: 2349 VAELQKEVVLLQAQLTLERKQKQDYITRSA------QTSRELA-----GLHHSLSHSLLA 2397
Query: 271 MARADRETRLFGGPRAL 287
+A+A T L R L
Sbjct: 2398 VAQAPEATVLEAETRRL 2414
Score = 39.3 bits (90), Expect = 0.005
Identities = 70/287 (24%), Positives = 120/287 (41%), Gaps = 64/287 (22%)
Query: 48 MAATQEL--LLQLQKDN--RDGRQRKQELEKLMR----------GLEAESESLNQRLQDL 93
+A QE LLQ Q D +G+ +Q L+KL L+ E +SL++ ++L
Sbjct: 409 LAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKE-REL 467
Query: 94 SERERSLLR-------------RRSQAAQPLQGEAREAARE-RAERVRRRLEEAERHKEY 139
++ R LR RR LQG++ + +E + E + + E ER +E
Sbjct: 468 LQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEM 527
Query: 140 LEQHSRQLQEQWEEL-----SSQLFYYGGELQSQKSTE--------QQLAAQLVTLQNEL 186
L + E EL + + + GEL Q+ TE +Q A+L + +N L
Sbjct: 528 LMGLEAKQSESLSELITLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTL 587
Query: 187 --ELAETKC------------ALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKE- 231
E+A+ + AL + L Q LQ E + Q+V ++ A+
Sbjct: 588 KTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEE-----ENQSVCSRMEAAEQARNA 642
Query: 232 VQVKVMEAAEELDA-WQSGRELCDGQLRGVQYSTESLMEEMARADRE 277
+QV + EA + +A W+ L + QL+ + + L ++ E
Sbjct: 643 LQVDLAEAEKRREALWEKNTHL-EAQLQKAEEAGAELQADLRDIQEE 688
Score = 38.9 bits (89), Expect = 0.007
Identities = 59/248 (23%), Positives = 108/248 (43%), Gaps = 33/248 (13%)
Query: 65 GRQRKQELEKLMRGL---EAESESLNQRLQDLSERERSL-----------LRRRSQAAQP 110
G+ ++ L L + L E E E+L ++Q+L E++R + L++R+Q
Sbjct: 1416 GKALQENLALLTQTLAEREEEVETLRGQIQEL-EKQREMQKAALELLSLDLKKRNQEVDL 1474
Query: 111 LQGEAREAARERA--ERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGEL--- 165
Q + +E + R+ E + ++E E+ + R+L++ E + L + EL
Sbjct: 1475 QQEQIQELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKK 1534
Query: 166 ----QSQKSTEQQLAAQLVTLQ---NELELAETKCALQEEKLQQDALQTAEAWAIFQEQT 218
+SQ+ Q L QLVTL+ ELE K Q++ +++ Q T
Sbjct: 1535 DQMIESQRGQVQDLKKQLVTLECLALELEENHHKMECQQKLIKELEGQRETQRVALTHLT 1594
Query: 219 VVLQVRPHS-DAKEVQVKVMEA-----AEELDAWQSGRELCDGQLRGVQYSTESLMEEMA 272
+ L+ R A+ Q+ +E+ A EL + Q+ +Q E L +++
Sbjct: 1595 LDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLE 1654
Query: 273 RADRETRL 280
R D+E L
Sbjct: 1655 RRDQELML 1662
Score = 38.5 bits (88), Expect = 0.009
Identities = 48/211 (22%), Positives = 90/211 (42%), Gaps = 17/211 (8%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQ----ELEKLMRGLEAES---ESLNQRLQDLS------ 94
+ +E + +L+KD R + ELEK + +E++ + L ++L L
Sbjct: 1503 LTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALEL 1562
Query: 95 ERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
E + + + + L+G+ RE R + LEE + + L+ L
Sbjct: 1563 EENHHKMECQQKLIKELEGQ-RETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVL 1621
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIF 214
+ +L E++SQ+ ++L Q L +LE + + LQ+E++Q Q I
Sbjct: 1622 ARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKIL 1681
Query: 215 QE--QTVVLQVRPHSDAKEVQVKVM-EAAEE 242
+E + + L +R Q ++M E AEE
Sbjct: 1682 EEDLEQIKLSLRERGRELTTQRQLMQERAEE 1712
Score = 35.4 bits (80), Expect = 0.079
Identities = 44/173 (25%), Positives = 73/173 (42%), Gaps = 24/173 (13%)
Query: 98 RSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQ 157
RS+L RR QA Q L+ + +E ++++ ++ E + L Q ++L + + L+ Q
Sbjct: 392 RSVLTRRRQAVQDLRQQLA-GCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDTLAGQ 450
Query: 158 LFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQ 217
GE+ S + L L+ +LE+ E EAW + +
Sbjct: 451 TVDLQGEVDSLSKERELLQKAREELRQQLEVLE-----------------QEAWRL-RRV 492
Query: 218 TVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQ-YSTESLME 269
V LQ++ S Q + E EEL RE L G++ +ESL E
Sbjct: 493 NVELQLQGDS----AQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSE 541
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 57.4 bits (137), Expect = 2e-08
Identities = 74/289 (25%), Positives = 120/289 (41%), Gaps = 46/289 (15%)
Query: 4 ATLGLPLPPIVIQPARRSLPP-IVTPASRRLGPRGGRH-LGSVSTAMAATQELLLQ---- 57
A G PLPP+ LPP + P+ RR+ G + S S +E +L+
Sbjct: 289 AMSGQPLPPV--------LPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQ 340
Query: 58 -----------------LQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSL 100
++ N + +R+Q L + R + L + Q+ ERER
Sbjct: 341 QLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQE 400
Query: 101 LRRRSQAAQPLQGE-AREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLF 159
R+ Q Q E RE R+R E R+ +E E K LE RQ Q +WE Q
Sbjct: 401 QERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE---RQRQLEWERNRRQ-- 455
Query: 160 YYGGELQSQKSTEQQ----LAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQ 215
EL +Q++ EQ+ L A+ TL+ ELE K E KLQ + +
Sbjct: 456 ----ELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIE 511
Query: 216 EQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYST 264
++R ++ +Q ++ E+ + L +++ + QL+ VQ ++
Sbjct: 512 STNKSRELR-IAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNS 559
Score = 45.4 bits (106), Expect = 8e-05
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 14/192 (7%)
Query: 66 RQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAER 125
+Q+ QE ++++ L E + LN +L+ + + L R S EA+E AR+
Sbjct: 528 QQQLQESQQMLGRLIPEKQILNDQLKQVQQNS---LHRDSLVTLKRALEAKELARQH--- 581
Query: 126 VRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNE 185
+R +L+E E+ Q Q +EL + +LQ QKS E + Q +
Sbjct: 582 LRDQLDEVEKETRSKLQEIDIFNNQLKELRE--IHNKQQLQKQKSMEAERLKQKEQERKI 639
Query: 186 LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDA 245
+EL + Q+E+ Q+ A + + W +Q Q RP +E ++K E+ ++ D
Sbjct: 640 IELEK-----QKEEAQRRAQERDKQWLEHVQQEDEHQ-RPRKLHEEEKLKREESVKKKDG 693
Query: 246 WQSGRELCDGQL 257
+ G++ +L
Sbjct: 694 EEKGKQEAQDKL 705
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 57.4 bits (137), Expect = 2e-08
Identities = 74/289 (25%), Positives = 120/289 (41%), Gaps = 46/289 (15%)
Query: 4 ATLGLPLPPIVIQPARRSLPP-IVTPASRRLGPRGGRH-LGSVSTAMAATQELLLQ---- 57
A G PLPP+ LPP + P+ RR+ G + S S +E +L+
Sbjct: 289 AMSGQPLPPV--------LPPEYIPPSFRRVRSGSGISVISSTSVDQRLPEEPVLEDEQQ 340
Query: 58 -----------------LQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSL 100
++ N + +R+Q L + R + L + Q+ ERER
Sbjct: 341 QLEKKLPVTFEDKKRENFERGNLELEKRRQALLEQQRKEQERLAQLERAEQERKERERQE 400
Query: 101 LRRRSQAAQPLQGE-AREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLF 159
R+ Q Q E RE R+R E R+ +E E K LE RQ Q +WE Q
Sbjct: 401 QERKRQLELEKQLEKQRELERQREEERRKEIERREAAKRELE---RQRQLEWERNRRQ-- 455
Query: 160 YYGGELQSQKSTEQQ----LAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQ 215
EL +Q++ EQ+ L A+ TL+ ELE K E KLQ + +
Sbjct: 456 ----ELLNQRNKEQEDIVVLKAKKKTLEFELEALNDKKHQLEGKLQDIRCRLTTQRQEIE 511
Query: 216 EQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYST 264
++R ++ +Q ++ E+ + L +++ + QL+ VQ ++
Sbjct: 512 STNKSRELR-IAEITHLQQQLQESQQMLGRLIPEKQILNDQLKQVQQNS 559
Score = 45.4 bits (106), Expect = 8e-05
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 14/192 (7%)
Query: 66 RQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAER 125
+Q+ QE ++++ L E + LN +L+ + + L R S EA+E AR+
Sbjct: 528 QQQLQESQQMLGRLIPEKQILNDQLKQVQQNS---LHRDSLVTLKRALEAKELARQH--- 581
Query: 126 VRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNE 185
+R +L+E E+ Q Q +EL + +LQ QKS E + Q +
Sbjct: 582 LRDQLDEVEKETRSKLQEIDIFNNQLKELRE--IHNKQQLQKQKSMEAERLKQKEQERKI 639
Query: 186 LELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDA 245
+EL + Q+E+ Q+ A + + W +Q Q RP +E ++K E+ ++ D
Sbjct: 640 IELEK-----QKEEAQRRAQERDKQWLEHVQQEDEHQ-RPRKLHEEEKLKREESVKKKDG 693
Query: 246 WQSGRELCDGQL 257
+ G++ +L
Sbjct: 694 EEKGKQEAQDKL 705
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 57.0 bits (136), Expect = 3e-08
Identities = 61/246 (24%), Positives = 118/246 (47%), Gaps = 31/246 (12%)
Query: 41 LGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSL 100
L S+ + T++ L + + +D +++ + EK EA+ SLN+R+Q + E
Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + A Q L+ EA +AA +E+ER + +E +++ +E+ E QL
Sbjct: 103 QERLATALQKLE-EAEKAA-----------DESERGMKVIESRAQKDEEKMEIQEIQLKE 150
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNEL-------ELAETKCALQEEKLQ--QDALQTAEAW 211
+ +++A +LV ++++L EL+E KCA EE+L+ + L++ EA
Sbjct: 151 AKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQ 210
Query: 212 AIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEM 271
A Q D E ++KV+ +++L ++ E + + ++ S + L E++
Sbjct: 211 AEKYSQ--------KEDRYEEEIKVL--SDKLKEAETRAEFAERSVTKLEKSIDDLEEKV 260
Query: 272 ARADRE 277
A A E
Sbjct: 261 AHAKEE 266
Score = 35.0 bits (79), Expect = 0.10
Identities = 45/170 (26%), Positives = 71/170 (41%), Gaps = 38/170 (22%)
Query: 124 ERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQL---AAQLV 180
E R E+AE K+ E S+QL+++ L +L K TE +L + L
Sbjct: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKL----------KGTEDELDKYSEALK 65
Query: 181 TLQNELELAETKCA--------------LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPH 226
Q +LELAE K L EE+L + + A A +E
Sbjct: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE------AEKA 119
Query: 227 SDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESL---MEEMAR 273
+D E +KV+E+ + D + E+ + QL+ ++ E EE+AR
Sbjct: 120 ADESERGMKVIESRAQKD--EEKMEIQEIQLKEAKHIAEDADRKYEEVAR 167
Score = 34.3 bits (77), Expect = 0.18
Identities = 34/165 (20%), Positives = 83/165 (50%), Gaps = 23/165 (13%)
Query: 84 ESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERH----KEY 139
+++ +++Q L + + L R QA ++AA +R++++ L ++ ++
Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEAD-----KKAAEDRSKQLEDELVSLQKKLKGTEDE 56
Query: 140 LEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEK 199
L+++S L++ E+L EL +K+T+ + A + +L ++L E + +E+
Sbjct: 57 LDKYSEALKDAQEKL---------ELAEKKATDAE--ADVASLNRRIQLVEEELDRAQER 105
Query: 200 LQQ--DALQTAEAWAIFQEQTV-VLQVRPHSDAKEVQVKVMEAAE 241
L L+ AE A E+ + V++ R D ++++++ ++ E
Sbjct: 106 LATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKE 150
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 56.2 bits (134), Expect = 4e-08
Identities = 71/291 (24%), Positives = 114/291 (39%), Gaps = 50/291 (17%)
Query: 48 MAATQELLLQLQKDNRDGRQ----RKQELEKLMRGLEAESESLNQRLQDLSERERSLLRR 103
M A + L + ++ R R+ + +E EK ++GLEAE L + L R +
Sbjct: 1675 MQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQD 1734
Query: 104 RSQAAQPLQG---------EAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
R + A + E + R ++ LEE + + E L R+L Q E L
Sbjct: 1735 RDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESL 1794
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNEL---------------ELAETKCALQEEK 199
+++L +S QQL Q+ L+ L E+K A EE+
Sbjct: 1795 TTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQ 1854
Query: 200 LQQDA---------LQTAE------AWAIFQEQTVVLQVRPHSDAKEVQVKVM-----EA 239
L+Q+ ++ AE + +E+ V Q+R + ++VK + EA
Sbjct: 1855 LEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEA 1914
Query: 240 AEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIR 290
EE Q+GR +L V S ES+ E+ RL GP R
Sbjct: 1915 EEEASRAQAGRRRLQRELEDVTESAESMNREVTTL--RNRLRRGPLTFTTR 1963
Score = 52.4 bits (124), Expect = 6e-07
Identities = 66/258 (25%), Positives = 111/258 (43%), Gaps = 28/258 (10%)
Query: 63 RDGRQRKQELEKLMRGLEAESESLNQRL---QDLSERERSLLRRRSQAAQPLQGEAREAA 119
R + +QELEKL R L+ ES L +++ Q +E R+ L R+ + Q A +
Sbjct: 1069 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1128
Query: 120 RERAE------RVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQ 173
RA+ + L EA+ E + ++Q +L +L GEL+ + +
Sbjct: 1129 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED--TLDS 1186
Query: 174 QLAAQLVTLQNELELAETKCALQEEKLQQDA----LQTAEAWAIFQEQTVVLQVRPHSDA 229
A Q + + E E+ E K L+EE +A L+ A+ + + Q R A
Sbjct: 1187 TNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGA 1246
Query: 230 KE-----VQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLM-----EEMARADRETR 279
E ++ +V E EL + Q+ R+ + + R ++ + + E ARA+ +
Sbjct: 1247 WEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEK 1306
Query: 280 LFGGPRALAIRRCVLGAL 297
L RA A V GAL
Sbjct: 1307 L---QRAQAELENVSGAL 1321
Score = 51.2 bits (121), Expect = 1e-06
Identities = 63/263 (23%), Positives = 107/263 (40%), Gaps = 31/263 (11%)
Query: 49 AATQEL-------LLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDL--SERERS 99
AA QEL L +L + R+ K EK LEAE L L L + +E
Sbjct: 1217 AAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGE 1276
Query: 100 LLRRRSQ-AAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQL 158
RRR + Q +QG A + R RAE +L+ A+ E + + + + LS +L
Sbjct: 1277 QRRRRLELQLQEVQGRAGDGERARAE-AAEKLQRAQAELENVSGALNEAESKTIRLSKEL 1335
Query: 159 FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDA---------LQTAE 209
+L + Q+ + L + + E + A E+L+++A LQTA+
Sbjct: 1336 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1395
Query: 210 A----WAIFQEQTV-------VLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLR 258
A W QE+ + R +A+ + ++ E E +D + GR +L
Sbjct: 1396 AQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD 1455
Query: 259 GVQYSTESLMEEMARADRETRLF 281
E + ++ +++ R F
Sbjct: 1456 DATMDLEQQRQLVSTLEKKQRKF 1478
Score = 48.9 bits (115), Expect = 7e-06
Identities = 60/232 (25%), Positives = 100/232 (43%), Gaps = 21/232 (9%)
Query: 56 LQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRR---RSQAAQPLQ 112
L L + + ++ ++ELE+ R L AE E+L D+ + L R QAA L+
Sbjct: 1511 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1570
Query: 113 GEAREAARE--RAERVRRRLEEAERHKEYLEQHSRQLQ---EQWEELSSQLFYYGGELQS 167
+ E E AE + RLE + + QH R LQ E EE QL + +
Sbjct: 1571 AQVTELEDELTAAEDAKLRLEVTVQALK--TQHERDLQGRDEAGEERRRQLAKQLRDAEV 1628
Query: 168 QKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS 227
++ E++ V + +LE L+E K Q + + A+ Q + + Q+
Sbjct: 1629 ERDEERKQRTLAVAARKKLE-----GELEELKAQMASAGQGKEEAVKQLRKMQAQM---- 1679
Query: 228 DAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETR 279
KE+ +V E + S + +L+G++ L EE+A +DR R
Sbjct: 1680 --KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARR 1729
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/241 (23%), Positives = 108/241 (44%), Gaps = 45/241 (18%)
Query: 44 VSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-LSERERS--- 99
+S +++T+ L Q+ ++ + K L +R +EAE+ L ++L++ + RER+
Sbjct: 1331 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1390
Query: 100 ----------LLRRRSQAAQPLQG--EAREAARERAERVRRRLEEAERHKEYLEQHSRQL 147
RR+ + A L+ EAR A AE + +RL E + LE+ R+L
Sbjct: 1391 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1450
Query: 148 QEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQT 207
Q++ ++ + L EQQ QLV+ L++++ + D L
Sbjct: 1451 QQELDDATMDL-------------EQQ--RQLVS------------TLEKKQRKFDQLLA 1483
Query: 208 AEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESL 267
E A+ + V + R ++ +E + + + L+ Q RE + Q R ++ E+L
Sbjct: 1484 EEKAAVL--RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541
Query: 268 M 268
+
Sbjct: 1542 L 1542
Score = 42.7 bits (99), Expect = 5e-04
Identities = 54/232 (23%), Positives = 89/232 (38%), Gaps = 28/232 (12%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQ 106
++ Q L + Q+D R + + EK R L E E+L L+D + +
Sbjct: 1137 SLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNA------- 1189
Query: 107 AAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQ-WEELSSQLFYYGGEL 165
Q E R + +++ LEE R E Q RQ Q EL+ QL
Sbjct: 1190 -----QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1244
Query: 166 QSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRP 225
+ + T L A++ L+ EL +T E++ ++ LQ E
Sbjct: 1245 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEV--------------- 1289
Query: 226 HSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRE 277
A + + EAAE+L Q+ E G L + T L +E++ + +
Sbjct: 1290 QGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ 1341
Score = 42.4 bits (98), Expect = 6e-04
Identities = 65/257 (25%), Positives = 117/257 (45%), Gaps = 55/257 (21%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQELEKLMRGLEA---ESESLNQRLQDLSERERSLLRRR 104
+ A EL + ++ RKQELE ++ LEA E E ++++Q +E+ +R
Sbjct: 921 LRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQ--TEK-----KRL 973
Query: 105 SQAAQPLQG--EAREAARERAE----RVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQL 158
Q Q L+ EA E AR++ + ++++ E LE + +L ++ + L +L
Sbjct: 974 QQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL 1033
Query: 159 FYYGGELQSQKSTEQQLAAQL--VTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQE 216
E SQ + E++ L + L+ E +A+ + L++E+ + L+
Sbjct: 1034 ----AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK--------- 1080
Query: 217 QTVVLQVRPHSDAKEVQVKVME---AAEELDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
L+ R ++ E+Q +++E AEEL A Q GR+ E L +AR
Sbjct: 1081 ----LKRRLDGESSELQEQMVEQQQRAEELRA-QLGRK------------EEELQAALAR 1123
Query: 274 ADRETRLFGGPRALAIR 290
A+ E GG RA ++
Sbjct: 1124 AEDE----GGARAQLLK 1136
Score = 37.4 bits (85), Expect = 0.021
Identities = 35/153 (22%), Positives = 67/153 (43%), Gaps = 5/153 (3%)
Query: 82 ESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLE 141
+ E L R Q+L ++ + L ++ ++ LQG + ERA + EAE E E
Sbjct: 875 QDEVLQARAQEL-QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEE 933
Query: 142 QHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE---E 198
R L + +EL + + ++ +Q+ + LQ ++ E +E +
Sbjct: 934 TRGR-LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQ 992
Query: 199 KLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKE 231
KLQ + + T F+E ++L+ + +KE
Sbjct: 993 KLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1025
Score = 36.6 bits (83), Expect = 0.035
Identities = 51/229 (22%), Positives = 93/229 (40%), Gaps = 23/229 (10%)
Query: 67 QRKQELEKLMRGLEAESESLNQRLQDLSERER--SLLRRRSQAAQPLQGEAREA---ARE 121
++ + +++L RG + L+ DL ++ + S L ++ + L E + A A E
Sbjct: 1435 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1494
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVT 181
ER E E L + + QE EEL Q EL++ S++ + +
Sbjct: 1495 ERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHE 1554
Query: 182 LQNELELAETKCALQEEKLQ----QDALQTAEAWAIFQEQTV-VLQVRPHSD-------- 228
L+ +AE A + + Q +D L AE + E TV L+ + D
Sbjct: 1555 LERACRVAEQ--AANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAG 1612
Query: 229 ---AKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+++ ++ +A E D + R L + ++ E L +MA A
Sbjct: 1613 EERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661
Score = 31.2 bits (69), Expect = 1.5
Identities = 40/172 (23%), Positives = 79/172 (45%), Gaps = 15/172 (8%)
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q E +A + ++V+ +++ R L+ QL+E+ L+ QL + T
Sbjct: 875 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 934
Query: 172 EQQLAA---QLVTLQNELEL---AETKCALQ---EEKLQQDALQTAEAWAIFQE---QTV 219
+LAA +L + +ELE E +C+ Q E+K Q +Q EA +E Q +
Sbjct: 935 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKL 994
Query: 220 VLQ-VRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEE 270
L+ V + K+ + ++ ++ R+L + +L ++S+++ EE
Sbjct: 995 QLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL--AEFSSQAAEEE 1044
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 56.2 bits (134), Expect = 4e-08
Identities = 71/291 (24%), Positives = 114/291 (39%), Gaps = 50/291 (17%)
Query: 48 MAATQELLLQLQKDNRDGRQ----RKQELEKLMRGLEAESESLNQRLQDLSERERSLLRR 103
M A + L + ++ R R+ + +E EK ++GLEAE L + L R +
Sbjct: 1667 MQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQD 1726
Query: 104 RSQAAQPLQG---------EAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
R + A + E + R ++ LEE + + E L R+L Q E L
Sbjct: 1727 RDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESL 1786
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNEL---------------ELAETKCALQEEK 199
+++L +S QQL Q+ L+ L E+K A EE+
Sbjct: 1787 TTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQ 1846
Query: 200 LQQDA---------LQTAE------AWAIFQEQTVVLQVRPHSDAKEVQVKVM-----EA 239
L+Q+ ++ AE + +E+ V Q+R + ++VK + EA
Sbjct: 1847 LEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEA 1906
Query: 240 AEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIR 290
EE Q+GR +L V S ES+ E+ RL GP R
Sbjct: 1907 EEEASRAQAGRRRLQRELEDVTESAESMNREVTTL--RNRLRRGPLTFTTR 1955
Score = 52.4 bits (124), Expect = 6e-07
Identities = 66/258 (25%), Positives = 111/258 (43%), Gaps = 28/258 (10%)
Query: 63 RDGRQRKQELEKLMRGLEAESESLNQRL---QDLSERERSLLRRRSQAAQPLQGEAREAA 119
R + +QELEKL R L+ ES L +++ Q +E R+ L R+ + Q A +
Sbjct: 1061 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1120
Query: 120 RERAE------RVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQ 173
RA+ + L EA+ E + ++Q +L +L GEL+ + +
Sbjct: 1121 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED--TLDS 1178
Query: 174 QLAAQLVTLQNELELAETKCALQEEKLQQDA----LQTAEAWAIFQEQTVVLQVRPHSDA 229
A Q + + E E+ E K L+EE +A L+ A+ + + Q R A
Sbjct: 1179 TNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGA 1238
Query: 230 KE-----VQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLM-----EEMARADRETR 279
E ++ +V E EL + Q+ R+ + + R ++ + + E ARA+ +
Sbjct: 1239 WEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEK 1298
Query: 280 LFGGPRALAIRRCVLGAL 297
L RA A V GAL
Sbjct: 1299 L---QRAQAELENVSGAL 1313
Score = 51.2 bits (121), Expect = 1e-06
Identities = 63/263 (23%), Positives = 107/263 (40%), Gaps = 31/263 (11%)
Query: 49 AATQEL-------LLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDL--SERERS 99
AA QEL L +L + R+ K EK LEAE L L L + +E
Sbjct: 1209 AAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGE 1268
Query: 100 LLRRRSQ-AAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQL 158
RRR + Q +QG A + R RAE +L+ A+ E + + + + LS +L
Sbjct: 1269 QRRRRLELQLQEVQGRAGDGERARAE-AAEKLQRAQAELENVSGALNEAESKTIRLSKEL 1327
Query: 159 FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDA---------LQTAE 209
+L + Q+ + L + + E + A E+L+++A LQTA+
Sbjct: 1328 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1387
Query: 210 A----WAIFQEQTV-------VLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLR 258
A W QE+ + R +A+ + ++ E E +D + GR +L
Sbjct: 1388 AQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD 1447
Query: 259 GVQYSTESLMEEMARADRETRLF 281
E + ++ +++ R F
Sbjct: 1448 DATMDLEQQRQLVSTLEKKQRKF 1470
Score = 48.9 bits (115), Expect = 7e-06
Identities = 60/232 (25%), Positives = 100/232 (43%), Gaps = 21/232 (9%)
Query: 56 LQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRR---RSQAAQPLQ 112
L L + + ++ ++ELE+ R L AE E+L D+ + L R QAA L+
Sbjct: 1503 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1562
Query: 113 GEAREAARE--RAERVRRRLEEAERHKEYLEQHSRQLQ---EQWEELSSQLFYYGGELQS 167
+ E E AE + RLE + + QH R LQ E EE QL + +
Sbjct: 1563 AQVTELEDELTAAEDAKLRLEVTVQALK--TQHERDLQGRDEAGEERRRQLAKQLRDAEV 1620
Query: 168 QKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS 227
++ E++ V + +LE L+E K Q + + A+ Q + + Q+
Sbjct: 1621 ERDEERKQRTLAVAARKKLE-----GELEELKAQMASAGQGKEEAVKQLRKMQAQM---- 1671
Query: 228 DAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETR 279
KE+ +V E + S + +L+G++ L EE+A +DR R
Sbjct: 1672 --KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARR 1721
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/241 (23%), Positives = 108/241 (44%), Gaps = 45/241 (18%)
Query: 44 VSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-LSERERS--- 99
+S +++T+ L Q+ ++ + K L +R +EAE+ L ++L++ + RER+
Sbjct: 1323 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1382
Query: 100 ----------LLRRRSQAAQPLQG--EAREAARERAERVRRRLEEAERHKEYLEQHSRQL 147
RR+ + A L+ EAR A AE + +RL E + LE+ R+L
Sbjct: 1383 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1442
Query: 148 QEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQT 207
Q++ ++ + L EQQ QLV+ L++++ + D L
Sbjct: 1443 QQELDDATMDL-------------EQQ--RQLVS------------TLEKKQRKFDQLLA 1475
Query: 208 AEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESL 267
E A+ + V + R ++ +E + + + L+ Q RE + Q R ++ E+L
Sbjct: 1476 EEKAAVL--RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1533
Query: 268 M 268
+
Sbjct: 1534 L 1534
Score = 42.7 bits (99), Expect = 5e-04
Identities = 54/232 (23%), Positives = 89/232 (38%), Gaps = 28/232 (12%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQ 106
++ Q L + Q+D R + + EK R L E E+L L+D + +
Sbjct: 1129 SLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNA------- 1181
Query: 107 AAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQ-WEELSSQLFYYGGEL 165
Q E R + +++ LEE R E Q RQ Q EL+ QL
Sbjct: 1182 -----QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1236
Query: 166 QSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRP 225
+ + T L A++ L+ EL +T E++ ++ LQ E
Sbjct: 1237 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEV--------------- 1281
Query: 226 HSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRE 277
A + + EAAE+L Q+ E G L + T L +E++ + +
Sbjct: 1282 QGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ 1333
Score = 42.4 bits (98), Expect = 6e-04
Identities = 65/257 (25%), Positives = 117/257 (45%), Gaps = 55/257 (21%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQELEKLMRGLEA---ESESLNQRLQDLSERERSLLRRR 104
+ A EL + ++ RKQELE ++ LEA E E ++++Q +E+ +R
Sbjct: 913 LRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQ--TEK-----KRL 965
Query: 105 SQAAQPLQG--EAREAARERAE----RVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQL 158
Q Q L+ EA E AR++ + ++++ E LE + +L ++ + L +L
Sbjct: 966 QQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL 1025
Query: 159 FYYGGELQSQKSTEQQLAAQL--VTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQE 216
E SQ + E++ L + L+ E +A+ + L++E+ + L+
Sbjct: 1026 ----AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK--------- 1072
Query: 217 QTVVLQVRPHSDAKEVQVKVME---AAEELDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
L+ R ++ E+Q +++E AEEL A Q GR+ E L +AR
Sbjct: 1073 ----LKRRLDGESSELQEQMVEQQQRAEELRA-QLGRK------------EEELQAALAR 1115
Query: 274 ADRETRLFGGPRALAIR 290
A+ E GG RA ++
Sbjct: 1116 AEDE----GGARAQLLK 1128
Score = 37.4 bits (85), Expect = 0.021
Identities = 35/153 (22%), Positives = 67/153 (43%), Gaps = 5/153 (3%)
Query: 82 ESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLE 141
+ E L R Q+L ++ + L ++ ++ LQG + ERA + EAE E E
Sbjct: 867 QDEVLQARAQEL-QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEE 925
Query: 142 QHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE---E 198
R L + +EL + + ++ +Q+ + LQ ++ E +E +
Sbjct: 926 TRGR-LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQ 984
Query: 199 KLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKE 231
KLQ + + T F+E ++L+ + +KE
Sbjct: 985 KLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1017
Score = 36.6 bits (83), Expect = 0.035
Identities = 51/229 (22%), Positives = 93/229 (40%), Gaps = 23/229 (10%)
Query: 67 QRKQELEKLMRGLEAESESLNQRLQDLSERER--SLLRRRSQAAQPLQGEAREA---ARE 121
++ + +++L RG + L+ DL ++ + S L ++ + L E + A A E
Sbjct: 1427 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1486
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVT 181
ER E E L + + QE EEL Q EL++ S++ + +
Sbjct: 1487 ERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHE 1546
Query: 182 LQNELELAETKCALQEEKLQ----QDALQTAEAWAIFQEQTV-VLQVRPHSD-------- 228
L+ +AE A + + Q +D L AE + E TV L+ + D
Sbjct: 1547 LERACRVAEQ--AANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAG 1604
Query: 229 ---AKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+++ ++ +A E D + R L + ++ E L +MA A
Sbjct: 1605 EERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1653
Score = 31.2 bits (69), Expect = 1.5
Identities = 40/172 (23%), Positives = 79/172 (45%), Gaps = 15/172 (8%)
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q E +A + ++V+ +++ R L+ QL+E+ L+ QL + T
Sbjct: 867 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 926
Query: 172 EQQLAA---QLVTLQNELEL---AETKCALQ---EEKLQQDALQTAEAWAIFQE---QTV 219
+LAA +L + +ELE E +C+ Q E+K Q +Q EA +E Q +
Sbjct: 927 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKL 986
Query: 220 VLQ-VRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEE 270
L+ V + K+ + ++ ++ R+L + +L ++S+++ EE
Sbjct: 987 QLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL--AEFSSQAAEEE 1036
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 56.2 bits (134), Expect = 4e-08
Identities = 71/291 (24%), Positives = 114/291 (39%), Gaps = 50/291 (17%)
Query: 48 MAATQELLLQLQKDNRDGRQ----RKQELEKLMRGLEAESESLNQRLQDLSERERSLLRR 103
M A + L + ++ R R+ + +E EK ++GLEAE L + L R +
Sbjct: 1708 MQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQD 1767
Query: 104 RSQAAQPLQG---------EAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEEL 154
R + A + E + R ++ LEE + + E L R+L Q E L
Sbjct: 1768 RDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESL 1827
Query: 155 SSQLFYYGGELQSQKSTEQQLAAQLVTLQNEL---------------ELAETKCALQEEK 199
+++L +S QQL Q+ L+ L E+K A EE+
Sbjct: 1828 TTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQ 1887
Query: 200 LQQDA---------LQTAE------AWAIFQEQTVVLQVRPHSDAKEVQVKVM-----EA 239
L+Q+ ++ AE + +E+ V Q+R + ++VK + EA
Sbjct: 1888 LEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEA 1947
Query: 240 AEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRLFGGPRALAIR 290
EE Q+GR +L V S ES+ E+ RL GP R
Sbjct: 1948 EEEASRAQAGRRRLQRELEDVTESAESMNREVTTL--RNRLRRGPLTFTTR 1996
Score = 52.4 bits (124), Expect = 6e-07
Identities = 66/258 (25%), Positives = 111/258 (43%), Gaps = 28/258 (10%)
Query: 63 RDGRQRKQELEKLMRGLEAESESLNQRL---QDLSERERSLLRRRSQAAQPLQGEAREAA 119
R + +QELEKL R L+ ES L +++ Q +E R+ L R+ + Q A +
Sbjct: 1102 RKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEG 1161
Query: 120 RERAE------RVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQ 173
RA+ + L EA+ E + ++Q +L +L GEL+ + +
Sbjct: 1162 GARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED--TLDS 1219
Query: 174 QLAAQLVTLQNELELAETKCALQEEKLQQDA----LQTAEAWAIFQEQTVVLQVRPHSDA 229
A Q + + E E+ E K L+EE +A L+ A+ + + Q R A
Sbjct: 1220 TNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGA 1279
Query: 230 KE-----VQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLM-----EEMARADRETR 279
E ++ +V E EL + Q+ R+ + + R ++ + + E ARA+ +
Sbjct: 1280 WEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEK 1339
Query: 280 LFGGPRALAIRRCVLGAL 297
L RA A V GAL
Sbjct: 1340 L---QRAQAELENVSGAL 1354
Score = 51.2 bits (121), Expect = 1e-06
Identities = 63/263 (23%), Positives = 107/263 (40%), Gaps = 31/263 (11%)
Query: 49 AATQEL-------LLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDL--SERERS 99
AA QEL L +L + R+ K EK LEAE L L L + +E
Sbjct: 1250 AAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGE 1309
Query: 100 LLRRRSQ-AAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQL 158
RRR + Q +QG A + R RAE +L+ A+ E + + + + LS +L
Sbjct: 1310 QRRRRLELQLQEVQGRAGDGERARAE-AAEKLQRAQAELENVSGALNEAESKTIRLSKEL 1368
Query: 159 FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDA---------LQTAE 209
+L + Q+ + L + + E + A E+L+++A LQTA+
Sbjct: 1369 SSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQ 1428
Query: 210 A----WAIFQEQTV-------VLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLR 258
A W QE+ + R +A+ + ++ E E +D + GR +L
Sbjct: 1429 AQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELD 1488
Query: 259 GVQYSTESLMEEMARADRETRLF 281
E + ++ +++ R F
Sbjct: 1489 DATMDLEQQRQLVSTLEKKQRKF 1511
Score = 48.9 bits (115), Expect = 7e-06
Identities = 60/232 (25%), Positives = 100/232 (43%), Gaps = 21/232 (9%)
Query: 56 LQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRR---RSQAAQPLQ 112
L L + + ++ ++ELE+ R L AE E+L D+ + L R QAA L+
Sbjct: 1544 LSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR 1603
Query: 113 GEAREAARE--RAERVRRRLEEAERHKEYLEQHSRQLQ---EQWEELSSQLFYYGGELQS 167
+ E E AE + RLE + + QH R LQ E EE QL + +
Sbjct: 1604 AQVTELEDELTAAEDAKLRLEVTVQALK--TQHERDLQGRDEAGEERRRQLAKQLRDAEV 1661
Query: 168 QKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHS 227
++ E++ V + +LE L+E K Q + + A+ Q + + Q+
Sbjct: 1662 ERDEERKQRTLAVAARKKLE-----GELEELKAQMASAGQGKEEAVKQLRKMQAQM---- 1712
Query: 228 DAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETR 279
KE+ +V E + S + +L+G++ L EE+A +DR R
Sbjct: 1713 --KELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARR 1762
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/241 (23%), Positives = 108/241 (44%), Gaps = 45/241 (18%)
Query: 44 VSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQD-LSERERS--- 99
+S +++T+ L Q+ ++ + K L +R +EAE+ L ++L++ + RER+
Sbjct: 1364 LSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRE 1423
Query: 100 ----------LLRRRSQAAQPLQG--EAREAARERAERVRRRLEEAERHKEYLEQHSRQL 147
RR+ + A L+ EAR A AE + +RL E + LE+ R+L
Sbjct: 1424 LQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRL 1483
Query: 148 QEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQT 207
Q++ ++ + L EQQ QLV+ L++++ + D L
Sbjct: 1484 QQELDDATMDL-------------EQQ--RQLVS------------TLEKKQRKFDQLLA 1516
Query: 208 AEAWAIFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESL 267
E A+ + V + R ++ +E + + + L+ Q RE + Q R ++ E+L
Sbjct: 1517 EEKAAVL--RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1574
Query: 268 M 268
+
Sbjct: 1575 L 1575
Score = 42.7 bits (99), Expect = 5e-04
Identities = 54/232 (23%), Positives = 89/232 (38%), Gaps = 28/232 (12%)
Query: 47 AMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQ 106
++ Q L + Q+D R + + EK R L E E+L L+D + +
Sbjct: 1170 SLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNA------- 1222
Query: 107 AAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQ-WEELSSQLFYYGGEL 165
Q E R + +++ LEE R E Q RQ Q EL+ QL
Sbjct: 1223 -----QQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGK 1277
Query: 166 QSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRP 225
+ + T L A++ L+ EL +T E++ ++ LQ E
Sbjct: 1278 GAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEV--------------- 1322
Query: 226 HSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRE 277
A + + EAAE+L Q+ E G L + T L +E++ + +
Sbjct: 1323 QGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQ 1374
Score = 42.4 bits (98), Expect = 6e-04
Identities = 65/257 (25%), Positives = 117/257 (45%), Gaps = 55/257 (21%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQELEKLMRGLEA---ESESLNQRLQDLSERERSLLRRR 104
+ A EL + ++ RKQELE ++ LEA E E ++++Q +E+ +R
Sbjct: 954 LRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQ--TEK-----KRL 1006
Query: 105 SQAAQPLQG--EAREAARERAE----RVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQL 158
Q Q L+ EA E AR++ + ++++ E LE + +L ++ + L +L
Sbjct: 1007 QQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL 1066
Query: 159 FYYGGELQSQKSTEQQLAAQL--VTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQE 216
E SQ + E++ L + L+ E +A+ + L++E+ + L+
Sbjct: 1067 ----AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEK--------- 1113
Query: 217 QTVVLQVRPHSDAKEVQVKVME---AAEELDAWQSGRELCDGQLRGVQYSTESLMEEMAR 273
L+ R ++ E+Q +++E AEEL A Q GR+ E L +AR
Sbjct: 1114 ----LKRRLDGESSELQEQMVEQQQRAEELRA-QLGRK------------EEELQAALAR 1156
Query: 274 ADRETRLFGGPRALAIR 290
A+ E GG RA ++
Sbjct: 1157 AEDE----GGARAQLLK 1169
Score = 37.4 bits (85), Expect = 0.021
Identities = 35/153 (22%), Positives = 67/153 (43%), Gaps = 5/153 (3%)
Query: 82 ESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLE 141
+ E L R Q+L ++ + L ++ ++ LQG + ERA + EAE E E
Sbjct: 908 QDEVLQARAQEL-QKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEE 966
Query: 142 QHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQE---E 198
R L + +EL + + ++ +Q+ + LQ ++ E +E +
Sbjct: 967 TRGR-LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQ 1025
Query: 199 KLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKE 231
KLQ + + T F+E ++L+ + +KE
Sbjct: 1026 KLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKE 1058
Score = 36.6 bits (83), Expect = 0.035
Identities = 51/229 (22%), Positives = 93/229 (40%), Gaps = 23/229 (10%)
Query: 67 QRKQELEKLMRGLEAESESLNQRLQDLSERER--SLLRRRSQAAQPLQGEAREA---ARE 121
++ + +++L RG + L+ DL ++ + S L ++ + L E + A A E
Sbjct: 1468 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1527
Query: 122 RAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVT 181
ER E E L + + QE EEL Q EL++ S++ + +
Sbjct: 1528 ERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHE 1587
Query: 182 LQNELELAETKCALQEEKLQ----QDALQTAEAWAIFQEQTV-VLQVRPHSD-------- 228
L+ +AE A + + Q +D L AE + E TV L+ + D
Sbjct: 1588 LERACRVAEQ--AANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAG 1645
Query: 229 ---AKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+++ ++ +A E D + R L + ++ E L +MA A
Sbjct: 1646 EERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1694
Score = 31.2 bits (69), Expect = 1.5
Identities = 40/172 (23%), Positives = 79/172 (45%), Gaps = 15/172 (8%)
Query: 112 QGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKST 171
Q E +A + ++V+ +++ R L+ QL+E+ L+ QL + T
Sbjct: 908 QDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEET 967
Query: 172 EQQLAA---QLVTLQNELEL---AETKCALQ---EEKLQQDALQTAEAWAIFQE---QTV 219
+LAA +L + +ELE E +C+ Q E+K Q +Q EA +E Q +
Sbjct: 968 RGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKL 1027
Query: 220 VLQ-VRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEE 270
L+ V + K+ + ++ ++ R+L + +L ++S+++ EE
Sbjct: 1028 QLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRL--AEFSSQAAEEE 1077
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 56.2 bits (134), Expect = 4e-08
Identities = 48/248 (19%), Positives = 108/248 (43%), Gaps = 20/248 (8%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQELEKLMRGLEA---ESESLNQRLQDLSERERSLLRRR 104
M +E++ + ++ R + E E+ +R LE E E + ++ + E E+ + +
Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK 377
Query: 105 SQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGE 164
Q + E RE+ E++R + E + +E + + ++ EQ EE+ Q +
Sbjct: 378 RQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQ 437
Query: 165 LQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVR 224
+ + E+++ Q ++ + E+ + QEEK+ + + E A QEQ ++ R
Sbjct: 438 EEKIREQEKKIREQEEKIREQEEMMQE----QEEKMGEQEGKMCEQEAKMQEQEEKMR-R 492
Query: 225 PHSDAKEVQVKVMEAAEEL------------DAWQSGRELCDGQLRGVQYSTESLMEEMA 272
+E + K+ E E++ W+ ++C+ + + + + +E
Sbjct: 493 QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 273 RADRETRL 280
++E RL
Sbjct: 553 MREQEVRL 560
Score = 47.0 bits (110), Expect = 3e-05
Identities = 43/196 (21%), Positives = 89/196 (45%), Gaps = 14/196 (7%)
Query: 67 QRKQELEKLM---RGLEAESESLNQRLQDLSER------ERSLLRRRSQAAQPLQGEARE 117
+RK E KL+ + L+AE++ L + LQ +S + E L R +Q + E
Sbjct: 236 KRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 295
Query: 118 AARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAA 177
+ER E+++ + E+ +E + + + E+ E++ Q + + + E+++
Sbjct: 296 KIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHE 355
Query: 178 Q-LVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQVRPHSDAKEVQVKV 236
Q + Q E E K QE++ +Q+A + I +++ ++R + + Q +
Sbjct: 356 QEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE---KIREQEEMMQEQEEK 412
Query: 237 MEAAEELDAWQSGREL 252
M EE W+ E+
Sbjct: 413 MGEQEE-KMWEQEEEM 427
Score = 42.4 bits (98), Expect = 6e-04
Identities = 31/162 (19%), Positives = 73/162 (45%), Gaps = 5/162 (3%)
Query: 41 LGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSL 100
+G M +E + + ++ R ++ +E EK +R E + + +Q+ E+
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
+ + +Q E E R + E++R + ++ +E + + +QEQ E++ Q
Sbjct: 473 EGKMCEQEAKMQ-EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 531
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQ 202
+ + + E+++ Q + ++ E + QEEK+Q+
Sbjct: 532 MCEQEEKMQEQEEKMRRQ----EEKMREQEVRLRQQEEKMQE 569
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/172 (18%), Positives = 82/172 (47%), Gaps = 10/172 (5%)
Query: 52 QELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPL 111
QE ++Q+ R++++++ + + + E + ++ + + E+E + + +
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 357
Query: 112 QGEAREAARERAERVR----RRLEEAE--RHKEYLEQHSRQLQEQWEELSSQLFYYGGEL 165
+ +E R+ E++R R+ +EA+ R +E + + +++EQ E + Q G +
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQE 417
Query: 166 QSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQ 217
+ E+++ Q + ++ E K QE+K+++ + E + QEQ
Sbjct: 418 EKMWEQEEEMQEQ----EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 465
Score = 38.1 bits (87), Expect = 0.012
Identities = 31/178 (17%), Positives = 79/178 (44%), Gaps = 18/178 (10%)
Query: 52 QELLLQLQKDNRDGRQRK-----QELEKLMRGLEAESESLNQRLQDLSERERSLLRRRS- 105
QE ++Q Q++ ++ K +E+++ + + E + ++ + + E+E + +
Sbjct: 402 QEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 461
Query: 106 -QAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGE 164
Q + GE E+ +++ + E+ R +E + + ++++EQ E++ Q +
Sbjct: 462 MQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 521
Query: 165 LQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVLQ 222
+ E+++ Q E K QEEK+++ + E ++Q +Q
Sbjct: 522 EEKMWEQEEKMCEQ-----------EEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 55.8 bits (133), Expect = 6e-08
Identities = 57/220 (25%), Positives = 99/220 (45%), Gaps = 21/220 (9%)
Query: 40 HLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERS 99
H V A ++L L + ++ + K EL+ EA S + +++L ER +S
Sbjct: 1676 HEDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQK---EANSRAPTTTMRNLVERLKS 1732
Query: 100 LLRRR-------SQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWE 152
L + S+A L+ E AA ER + E ++ +++H+R+L+ Q E
Sbjct: 1733 QLALKEKQQKALSRALLELRAEMTAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVE 1792
Query: 153 ELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNEL---ELAETKCALQEEKLQQDALQTAE 209
+L+ L L++ K+ E L L L NEL + A K ++E++ Q + E
Sbjct: 1793 DLNENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQ---ENDE 1849
Query: 210 AWAIFQEQTVVLQVRPHSDAK-----EVQVKVMEAAEELD 244
+ T LQ +P +D K E+Q KV + +L+
Sbjct: 1850 LKRQIKRLTSGLQGKPLTDNKQSLIEELQRKVKKLENQLE 1889
Score = 41.2 bits (95), Expect = 0.001
Identities = 46/239 (19%), Positives = 105/239 (43%), Gaps = 29/239 (12%)
Query: 52 QELLLQLQKDNRDGRQR-------KQELEKLMRGLEAESESLNQRLQDLSERERSLLRRR 104
QE+ L L++ + G ++ K ++ KL LE +S R E L ++
Sbjct: 64 QEVELALEEVEKAGEEQAKFENQLKTKVMKLENELEMAQQSAGGRDTRFLRNEICQLEKQ 123
Query: 105 -SQAAQPLQGEAREAARERA--ERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYY 161
Q + L+ +E +E+ E++ R EEAE L + +++L+++ E+L + Y
Sbjct: 124 LEQKDRELEDMEKELEKEKKVNEQLALRNEEAENENSKLRRENKRLKKKNEQLCQDIIDY 183
Query: 162 GGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVVL 221
++ SQK T L++ + E ++ Q K + +Q + E +
Sbjct: 184 QKQIDSQKET-------LLSRRGE----DSDYRSQLSKKNYELIQYLDEIQTLTEANEKI 232
Query: 222 QVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRETRL 280
+V+ K ++ V E + D + +++ + + T+++++++ + + +L
Sbjct: 233 EVQNQEMRKNLEESVQEMEKMTDEY--------NRMKAIVHQTDNVIDQLKKENDHYQL 283
Score = 32.3 bits (72), Expect = 0.67
Identities = 43/238 (18%), Positives = 103/238 (43%), Gaps = 27/238 (11%)
Query: 39 RHLGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKL------MRGLEAESESLNQRLQD 92
++L + T A +++ +Q Q+ ++ + QE+EK+ M+ + +++++ +L+
Sbjct: 217 QYLDEIQTLTEANEKIEVQNQEMRKNLEESVQEMEKMTDEYNRMKAIVHQTDNVIDQLKK 276
Query: 93 LSERER-------SLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSR 145
++ + LL+ +++ P+ E + + +E +++ L
Sbjct: 277 ENDHYQLQVQELTDLLKSKNEEDDPIMVAVNAKVEEWKLILSSKDDEIIEYQQMLHNLRE 336
Query: 146 QLQE-QWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELE-----LAETKCALQEEK 199
+L+ Q + S + +Q + S + L Q+ E+E + + K LQ K
Sbjct: 337 KLKNAQLDADKSNVMALQQGIQERDSQIKMLTEQVEQYTKEMEKNTCIIEDLKNELQRNK 396
Query: 200 -----LQQDALQTAEAWAIFQEQTVVLQ---VRPHSDAKEVQVKVMEAAEELDAWQSG 249
QQ ++ I +E+T + +DA+E +++EA + L ++SG
Sbjct: 397 GASTLSQQTHMKIQSTLDILKEKTKEAERTAELAEADAREKDKELVEALKRLKDYESG 454
Score = 29.3 bits (64), Expect = 5.7
Identities = 37/182 (20%), Positives = 80/182 (43%), Gaps = 11/182 (6%)
Query: 57 QLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQAAQPLQGEAR 116
Q++ N++ K++L + + E E++ N+ D +++ + S + + E +
Sbjct: 1006 QVESINKELEITKEKLHTIEQAWEQETKLGNESSMDKAKKSITNSDIVSISKKITMLEMK 1065
Query: 117 EAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLA 176
E R+R E ++ E+L +Q++E+ EL ++ + EQ L
Sbjct: 1066 ELNE------RQRAEHCQKMYEHLRTSLKQMEERNFELETKFAELTKINLDAQKVEQMLR 1119
Query: 177 AQLV-TLQNELELAETKCALQEEK----LQQDALQTAEAWAIFQEQTVVLQVRPHSDAKE 231
+L ++ + A+ + L+ EK L+ + + E I + Q +L + S KE
Sbjct: 1120 DELADSVSKAVSDADRQRILELEKNEMELKVEVSKLREISDIARRQVEILNAQQQSRDKE 1179
Query: 232 VQ 233
V+
Sbjct: 1180 VE 1181
Score = 28.9 bits (63), Expect = 7.4
Identities = 42/223 (18%), Positives = 92/223 (41%), Gaps = 27/223 (12%)
Query: 42 GSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRL-QDLSERERSL 100
G S T E L + ++ R +++L+ L +E++S N+ L ++L E+ER L
Sbjct: 564 GKRSATSGLTTEDLNLTENISQGDRISERKLDLLSLKNMSEAQSKNEFLSRELIEKERDL 623
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R R+ A + + +L+E + LE+ +++ + +E+
Sbjct: 624 ERSRTVIA----------------KFQNKLKELVEENKQLEEGMKEILQAIKEMQKDPDV 667
Query: 161 YGGEL--------QSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWA 212
GGE + + E + A + L+ + + E+L+Q+ ++ +
Sbjct: 668 KGGETSLIIPSLERLVNAIESKNAEGIFDASLHLKAQVDQLTGRNEELRQELRESRKEAI 727
Query: 213 IFQEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDG 255
+ +Q ++ D E + ++ +E + G +L DG
Sbjct: 728 NYSQQLAKANLK--IDHLEKETSLLRQSEGSNVVFKGIDLPDG 768
>gi|238908495 similar to pleckstrin homology domain protein (5V327)
[Homo sapiens]
Length = 506
Score = 55.1 bits (131), Expect = 1e-07
Identities = 66/246 (26%), Positives = 107/246 (43%), Gaps = 39/246 (15%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQA 107
M T+EL LQ R++++ELE+L + LEAE + + +Q+L + + R
Sbjct: 171 MEETEELCLQ--------REQREELERLNQVLEAEKQQFEEVVQELRMEQEQIKRELELT 222
Query: 108 AQPLQG--EAREAARERAERVRRRLEEAERHK-------EYLEQHSRQLQEQWEELSSQL 158
A+ L+G + ++ R E +++ LEE K E E H + L Q E+
Sbjct: 223 ARCLKGVEQEKKELRHLTESLQQTLEELSIEKKKTLEMLEENENHLQTLANQSEQPPPSG 282
Query: 159 FYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEK----LQQDALQTAEAWAIF 214
+ Q ++ +Q L +L+ + E E AL+EE+ Q ALQ +
Sbjct: 283 GLHSNLRQIEEKMQQLLEEKLLAEKRMKENEERSRALEEEREFYSSQSQALQNS-----L 337
Query: 215 QEQTVVLQVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLM-----E 269
QE T Q EV+V+ +D + RE +G LR ++ S + E
Sbjct: 338 QELTAEKQQAERELKAEVKVR-------MDLERRLRE-AEGALRSLEQGLNSKVRNKEKE 389
Query: 270 EMARAD 275
E RAD
Sbjct: 390 ERMRAD 395
>gi|63252900 tropomyosin 1 alpha chain isoform 4 [Homo sapiens]
Length = 284
Score = 55.1 bits (131), Expect = 1e-07
Identities = 56/243 (23%), Positives = 114/243 (46%), Gaps = 25/243 (10%)
Query: 41 LGSVSTAMAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSL 100
L S+ + T++ L + + +D +++ + EK EA+ SLN+R+Q + E
Sbjct: 43 LVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRA 102
Query: 101 LRRRSQAAQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFY 160
R + A Q L+ EA +AA +E+ER + +E +++ +E+ E QL
Sbjct: 103 QERLATALQKLE-EAEKAA-----------DESERGMKVIESRAQKDEEKMEIQEIQLKE 150
Query: 161 YGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQDALQTAEAWAIFQEQTVV 220
+ +++A +LV ++++LE AE + L E +++Q E +QT+
Sbjct: 151 AKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGQVRQ-----LEEQLRIMDQTLK 205
Query: 221 L------QVRPHSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARA 274
+ D E ++KV+ +++L ++ E + + ++ S + L E++A A
Sbjct: 206 ALMAAEDKYSQKEDRYEEEIKVL--SDKLKEAETRAEFAERSVTKLEKSIDDLEEKVAHA 263
Query: 275 DRE 277
E
Sbjct: 264 KEE 266
Score = 35.0 bits (79), Expect = 0.10
Identities = 45/170 (26%), Positives = 71/170 (41%), Gaps = 38/170 (22%)
Query: 124 ERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQL---AAQLV 180
E R E+AE K+ E S+QL+++ L +L K TE +L + L
Sbjct: 16 ENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKL----------KGTEDELDKYSEALK 65
Query: 181 TLQNELELAETKCA--------------LQEEKLQQDALQTAEAWAIFQEQTVVLQVRPH 226
Q +LELAE K L EE+L + + A A +E
Sbjct: 66 DAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEE------AEKA 119
Query: 227 SDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESL---MEEMAR 273
+D E +KV+E+ + D + E+ + QL+ ++ E EE+AR
Sbjct: 120 ADESERGMKVIESRAQKD--EEKMEIQEIQLKEAKHIAEDADRKYEEVAR 167
Score = 34.3 bits (77), Expect = 0.18
Identities = 34/165 (20%), Positives = 83/165 (50%), Gaps = 23/165 (13%)
Query: 84 ESLNQRLQDLSERERSLLRRRSQAAQPLQGEAREAARERAERVRRRLEEAERH----KEY 139
+++ +++Q L + + L R QA ++AA +R++++ L ++ ++
Sbjct: 2 DAIKKKMQMLKLDKENALDRAEQAEAD-----KKAAEDRSKQLEDELVSLQKKLKGTEDE 56
Query: 140 LEQHSRQLQEQWEELSSQLFYYGGELQSQKSTEQQLAAQLVTLQNELELAETKCALQEEK 199
L+++S L++ E+L EL +K+T+ + A + +L ++L E + +E+
Sbjct: 57 LDKYSEALKDAQEKL---------ELAEKKATDAE--ADVASLNRRIQLVEEELDRAQER 105
Query: 200 LQQ--DALQTAEAWAIFQEQTV-VLQVRPHSDAKEVQVKVMEAAE 241
L L+ AE A E+ + V++ R D ++++++ ++ E
Sbjct: 106 LATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKE 150
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 55.1 bits (131), Expect = 1e-07
Identities = 52/232 (22%), Positives = 110/232 (47%), Gaps = 17/232 (7%)
Query: 48 MAATQELLLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDLSERERSLLRRRSQA 107
+ T++ + + + ++ +++ ++ EK EA+ SLN+R+Q + E R + A
Sbjct: 50 LKGTEDEVEKYSESVKEAQEKLEQAEKKATDAEADVASLNRRIQLVEEELDRAQERLATA 109
Query: 108 AQPLQGEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGELQS 167
Q L+ EA +AA +E+ER + +E + + +E+ E QL +
Sbjct: 110 LQKLE-EAEKAA-----------DESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAED 157
Query: 168 QKSTEQQLAAQLVTLQNELELAETKCALQEEKLQQ--DALQTAEAWAIFQEQTVVLQVRP 225
+++A +LV L+ ELE +E + + E + +Q + L+T + A+ +
Sbjct: 158 SDRKYEEVARKLVILEGELERSEERAEVAESRARQLEEELRTMDQ-ALKSLMASEEEYST 216
Query: 226 HSDAKEVQVKVMEAAEELDAWQSGRELCDGQLRGVQYSTESLMEEMARADRE 277
D E ++K++E E+L ++ E + + ++ + + L E +A A E
Sbjct: 217 KEDKYEEEIKLLE--EKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEE 266
Score = 33.9 bits (76), Expect = 0.23
Identities = 31/136 (22%), Positives = 67/136 (49%), Gaps = 10/136 (7%)
Query: 116 REAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQLFYYGGEL-QSQKSTEQ- 173
+E A +RAE+ ++AE + LE+ + LQ++ + ++ Y + ++Q+ EQ
Sbjct: 15 KENAIDRAEQAEADKKQAEDRCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQA 74
Query: 174 -----QLAAQLVTLQNELELAETKCALQEEKLQQ--DALQTAEAWAIFQEQTV-VLQVRP 225
A + +L ++L E + +E+L L+ AE A E+ + V++ R
Sbjct: 75 EKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRA 134
Query: 226 HSDAKEVQVKVMEAAE 241
D ++++++ M+ E
Sbjct: 135 MKDEEKMELQEMQLKE 150
Score = 32.3 bits (72), Expect = 0.67
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Query: 55 LLQLQKDNRDGRQRKQELEKLMRGLEAESESLNQRLQDL--SERERSLLRRRSQAAQPLQ 112
L+ L+ + +R + E R LE E +++Q L+ L SE E S + + L
Sbjct: 169 LVILEGELERSEERAEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL 228
Query: 113 GEAREAARERAERVRRRLEEAERHKEYLEQHSRQLQEQWEELSSQL 158
E + A RAE R + + E+ + LE+ +E+ E+ L
Sbjct: 229 EEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTL 274
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.130 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,857,266
Number of Sequences: 37866
Number of extensions: 566589
Number of successful extensions: 10150
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 349
Number of HSP's successfully gapped in prelim test: 919
Number of HSP's that attempted gapping in prelim test: 4388
Number of HSP's gapped (non-prelim): 3841
length of query: 357
length of database: 18,247,518
effective HSP length: 103
effective length of query: 254
effective length of database: 14,347,320
effective search space: 3644219280
effective search space used: 3644219280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.