BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|112293277 DnaJ (Hsp40) homolog, subfamily C, member 8 [Homo sapiens] (253 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|112293277 DnaJ (Hsp40) homolog, subfamily C, member 8 [Homo s... 501 e-142 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 64 1e-10 gi|8922563 DnaJ (Hsp40) homolog, subfamily C, member 17 [Homo sa... 62 4e-10 gi|119943096 dopamine receptor interacting protein [Homo sapiens] 59 3e-09 gi|6005872 SEC63-like protein [Homo sapiens] 58 9e-09 gi|23503241 DnaJ homolog, subfamily B, member 8 [Homo sapiens] 58 9e-09 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 55 4e-08 gi|148746195 trichohyalin [Homo sapiens] 54 1e-07 gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo s... 53 2e-07 gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo s... 53 2e-07 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 53 3e-07 gi|47777312 DnaJ (Hsp40) homolog, subfamily B, member 3 [Homo sa... 52 6e-07 gi|17388799 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform ... 51 8e-07 gi|4885495 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform b... 51 8e-07 gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 50 1e-06 gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform... 50 1e-06 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 50 2e-06 gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo s... 50 2e-06 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 50 2e-06 gi|21361912 DnaJ (Hsp40) homolog, subfamily C, member 1 [Homo sa... 50 2e-06 gi|194306642 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo ... 50 2e-06 gi|194306640 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo ... 50 2e-06 gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo sap... 50 2e-06 gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 50 2e-06 gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 50 2e-06 gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 50 2e-06 gi|72534740 DnaJ (Hsp40) homolog, subfamily B, member 14 isoform... 49 3e-06 gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precurso... 49 4e-06 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 49 4e-06 gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 49 5e-06 >gi|112293277 DnaJ (Hsp40) homolog, subfamily C, member 8 [Homo sapiens] Length = 253 Score = 501 bits (1291), Expect = e-142 Identities = 253/253 (100%), Positives = 253/253 (100%) Query: 1 MAASGESGTSGGGGSTEEAFMTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFE 60 MAASGESGTSGGGGSTEEAFMTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFE Sbjct: 1 MAASGESGTSGGGGSTEEAFMTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFE 60 Query: 61 VLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRAL 120 VLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRAL Sbjct: 61 VLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRAL 120 Query: 121 DVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKER 180 DVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKER Sbjct: 121 DVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKER 180 Query: 181 EAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRT 240 EAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRT Sbjct: 181 EAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRT 240 Query: 241 FLRPPKVKMEQRE 253 FLRPPKVKMEQRE Sbjct: 241 FLRPPKVKMEQRE 253 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 64.3 bits (155), Expect = 1e-10 Identities = 42/156 (26%), Positives = 86/156 (55%), Gaps = 4/156 (2%) Query: 87 DKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGK 146 ++ +++ +R ++ E +K + ++ +KK + + KE E KE +K+ +++ + Sbjct: 89 ERKKEERERKKRRREKENKEGEEK-EKRKKKEKKERGRTSKEGKERERKEERKREERKER 147 Query: 147 PTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREE---EIEAQEKAK 203 EE + E ++ K+ K E E +RKE+E KE +R+R R+E E E +E+ + Sbjct: 148 ERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRE 207 Query: 204 REREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNR 239 R++E +K E ++ + D N++ +GK+E+K R Sbjct: 208 RKKERKKKEERKKERQKDRQTNWREKERGKRERKER 243 Score = 42.7 bits (99), Expect = 3e-04 Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 22/128 (17%) Query: 135 KERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRK--------EREAKEMH 186 +ER+ + +KEGK +E + E K+ ++ K E E KR+ ER+ +E Sbjct: 41 REREIETRKEGK----KERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96 Query: 187 ERKRQREEEI-EAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPP 245 +KR+RE+E E +EK KR+++ E+ GR + + +KE++ R + Sbjct: 97 RKKRRREKENKEGEEKEKRKKK-----EKKERGRTSK----EGKERERKEERKREERKER 147 Query: 246 KVKMEQRE 253 + K E+RE Sbjct: 148 ERKKEERE 155 Score = 42.7 bits (99), Expect = 3e-04 Identities = 35/135 (25%), Positives = 68/135 (50%), Gaps = 18/135 (13%) Query: 135 KERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHE-----RK 189 KERK++ K+ K ++++ E K+ K+ + E + KRK++E KE ++ Sbjct: 75 KERKRERGKKEKKGERKKEERERKKRRREKENKE--GEEKEKRKKKEKKERGRTSKEGKE 132 Query: 190 RQREEEIEAQEKAKREREWQ-----------KNFEESRDGRVDSWRNFQANTKGKKEKKN 238 R+R+EE + +E+ +RER+ + K E + G + R + + KK ++N Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192 Query: 239 RTFLRPPKVKMEQRE 253 R + + + E+RE Sbjct: 193 RKERKKERERKERRE 207 Score = 42.0 bits (97), Expect = 5e-04 Identities = 35/137 (25%), Positives = 67/137 (48%), Gaps = 22/137 (16%) Query: 88 KNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKP 147 K ++ +R + + E ++ K E++KR + K+ +ERK++ K+E K Sbjct: 116 KKKEKKERGRTSKEGKERERK-----EERKREERKERERKKEEREKERERKERKKRERKQ 170 Query: 148 TIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQ-------- 199 +E++ K+ K+ K + ++KERE KE ERK++R+++ E + Sbjct: 171 VGEKEEER---KEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQ 227 Query: 200 ------EKAKREREWQK 210 E+ KRER+ +K Sbjct: 228 TNWREKERGKRERKERK 244 Score = 38.1 bits (87), Expect = 0.007 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 13/80 (16%) Query: 174 EIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGK 233 EI+ +ERE + E K++RE E ++K +RERE +K E R +GK Sbjct: 37 EIREREREIETRKEGKKERESE---RKKERREREKRKREREKERKR----------ERGK 83 Query: 234 KEKKNRTFLRPPKVKMEQRE 253 KEKK + K +RE Sbjct: 84 KEKKGERKKEERERKKRRRE 103 Score = 28.9 bits (63), Expect = 4.5 Identities = 35/131 (26%), Positives = 57/131 (43%), Gaps = 20/131 (15%) Query: 69 TDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKE 128 T +E K+R R+ K ++ +R +K E + + +E+KKR Q G++ Sbjct: 126 TSKEGKERERK-----EERKREERKERERKKEEREKERER----KERKKRERK--QVGEK 174 Query: 129 YVEHTVKERK---------KQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKE 179 E KERK K+ KKE + E E K+ K+ + + + KE Sbjct: 175 EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234 Query: 180 REAKEMHERKR 190 R +E ERK+ Sbjct: 235 RGKRERKERKK 245 >gi|8922563 DnaJ (Hsp40) homolog, subfamily C, member 17 [Homo sapiens] Length = 304 Score = 62.4 bits (150), Expect = 4e-10 Identities = 45/157 (28%), Positives = 86/157 (54%), Gaps = 5/157 (3%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKR 118 + +L I+ + D+E+KK +RQ ++ HPDKN D+ RA + F + +A ++L D + Sbjct: 13 YALLGIEEKAADKEVKKAYRQKALSCHPDKNPDN-PRAAELFHQLSQALEVLTDAAARAA 71 Query: 119 ALDVIQAGKEYVEHTVK--ERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIK 176 V +A K+ E T K E++K++K + + + E ++ + T L E+E + Sbjct: 72 YDKVRKAKKQAAERTQKLDEKRKKVKLDLEARERQAQAQESEEEEESRSTRTLEQEIE-R 130 Query: 177 RKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFE 213 +E ++++ E++R E+I QE+ +R R +N E Sbjct: 131 LREEGSRQLEEQQRLIREQIR-QERDQRLRGKAENTE 166 >gi|119943096 dopamine receptor interacting protein [Homo sapiens] Length = 702 Score = 59.3 bits (142), Expect = 3e-09 Identities = 29/72 (40%), Positives = 47/72 (65%), Gaps = 2/72 (2%) Query: 46 LTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDK 105 LT G LNPF VL ++ +D E+KK +RQL+++VHPDKN RA++AF+ + Sbjct: 432 LTMAGVPEDELNPFHVLGVEATASDVELKKAYRQLAVMVHPDKNHH--PRAEEAFKVLRA 489 Query: 106 AYKLLLDQEQKK 117 A+ ++ + E++K Sbjct: 490 AWDIVSNAEKRK 501 >gi|6005872 SEC63-like protein [Homo sapiens] Length = 760 Score = 57.8 bits (138), Expect = 9e-09 Identities = 29/73 (39%), Positives = 42/73 (57%), Gaps = 5/73 (6%) Query: 45 RLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVD 104 ++++ Y NP+EVL +DP T EIKK++R LS+ HPDK D+ F + Sbjct: 92 KVSKTDREYQEYNPYEVLNLDPGATVAEIKKQYRLLSLKYHPDKGGDEV-----MFMRIA 146 Query: 105 KAYKLLLDQEQKK 117 KAY L D+E +K Sbjct: 147 KAYAALTDEESRK 159 Score = 31.6 bits (70), Expect = 0.69 Identities = 21/103 (20%), Positives = 50/103 (48%), Gaps = 9/103 (8%) Query: 136 ERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKERE----AKEMHERKRQ 191 ++KK LKK+ P ++ + + KQA + E +K E E + E + Sbjct: 527 KKKKPLKKKPTPVLLPQSKQQKQKQA----NGVVGNEAAVKEDEEEVSDKGSDSEEEETN 582 Query: 192 REEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKK 234 R+ + E + + R+ + +++ ++++D + W+ Q + + K+ Sbjct: 583 RDSQSEKDDGSDRDSDREQDEKQNKDDEAE-WQELQQSIQRKE 624 >gi|23503241 DnaJ homolog, subfamily B, member 8 [Homo sapiens] Length = 232 Score = 57.8 bits (138), Expect = 9e-09 Identities = 28/64 (43%), Positives = 44/64 (68%), Gaps = 2/64 (3%) Query: 57 NPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQK 116 N +EVL + + E+IKK +R+L++ HPDKN D+ + A+K F+ V +AY++L D K Sbjct: 3 NYYEVLGVQASASPEDIKKAYRKLALRWHPDKNPDNKEEAEKKFKLVSEAYEVLSD--SK 60 Query: 117 KRAL 120 KR+L Sbjct: 61 KRSL 64 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 55.5 bits (132), Expect = 4e-08 Identities = 45/163 (27%), Positives = 85/163 (52%), Gaps = 19/163 (11%) Query: 69 TDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALD-VIQAGK 127 T EE K+R L+I + +++ ++ + + V KA + L QE K+R + ++Q + Sbjct: 574 TIEERKERLESLNI----QREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQEHE 629 Query: 128 EYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAEL----EIKRKEREAK 183 + + TV+ER +Q+KK E + FK + +L + ++++ E+E K Sbjct: 630 QIKKKTVRERLEQIKKT-------ELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKK 682 Query: 184 EMHERKRQREEEIEAQEKAKRERE---WQKNFEESRDGRVDSW 223 E+ ER + +E++I+ E+AKR E + +EE R +D W Sbjct: 683 ELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLW 725 Score = 52.8 bits (125), Expect = 3e-07 Identities = 66/259 (25%), Positives = 130/259 (50%), Gaps = 47/259 (18%) Query: 26 EVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTD----EEIKKRFRQLS 81 E +QI+K+ +V QI++ ++ +++ ++ ++DP+ E+++K ++L Sbjct: 627 EHEQIKKK-TVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQ 685 Query: 82 I-LVHPDKNQDDADRAQKAFEA--VDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVK-ER 137 L + +K D +RA++ E + AY +EQ+ + +D+ + +E T++ ER Sbjct: 686 ERLKNQEKKIDYFERAKRLEEIPLIKSAY-----EEQRIKDMDLWEQQEEERITTMQLER 740 Query: 138 KKQLKKEGKPTIVEEDDPELF-------KQAVYKQTMKLFAELEIKRKEREAKEMH---- 186 +K L+ + + + + ED +LF +Q+VY++ +K F +ER A+E H Sbjct: 741 EKALEHKNRMSRMLEDR-DLFVMRLKAARQSVYEEKLKQF-------EERLAEERHNRLE 792 Query: 187 ERKRQREEEIEAQEKAKREREWQKNFEE------------SRDGRVDSWRNFQANTKGKK 234 ERKRQR+EE ++E E Q+ EE R R + R +Q K + Sbjct: 793 ERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLE 852 Query: 235 EKKNRTFLRPPKVKMEQRE 253 E + + R ++++E+RE Sbjct: 853 EVERKK--RQRELEIEERE 869 Score = 39.3 bits (90), Expect = 0.003 Identities = 58/225 (25%), Positives = 105/225 (46%), Gaps = 37/225 (16%) Query: 26 EVKQIEKRDSVLTS--KNQ------IERLTRPGSSYFNLNPFEVLQI-DPEVTDEEIKKR 76 +V+Q+EK L KNQ ER R + +E +I D ++ +++ ++R Sbjct: 673 QVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEER 732 Query: 77 FRQLSILVHPDKNQDDADRAQKAFEAVD------KAYKLLLDQEQKKRALDVIQAGKEYV 130 + + +K + +R + E D KA + + +E+ K+ + + E Sbjct: 733 ITTMQL--EREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLA---EER 787 Query: 131 EHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELE----IKRKE------- 179 + ++ERK+Q K+E + T E + E ++A +Q +K E E KR+E Sbjct: 788 HNRLEERKRQRKEERRITYYREKEEEEQRRA-EEQMLKEREERERAERAKREEELREYQE 846 Query: 180 --REAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDS 222 ++ +E+ +KRQRE EIE +E R RE ++ +S R DS Sbjct: 847 RVKKLEEVERKKRQRELEIEERE---RRREEERRLGDSSLSRKDS 888 Score = 34.3 bits (77), Expect = 0.11 Identities = 35/178 (19%), Positives = 82/178 (46%), Gaps = 27/178 (15%) Query: 32 KRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQD 91 +R+ L KN++ R+ + + V +E++K+ +L+ H N+ Sbjct: 739 EREKALEHKNRMSRMLEDRDLFV----MRLKAARQSVYEEKLKQFEERLAEERH---NRL 791 Query: 92 DADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVE 151 + + Q+ E Y+ ++EQ++ +++ +E +ER ++ K+E Sbjct: 792 EERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREE------RERAERAKRE------- 838 Query: 152 EDDPELFKQAVYKQTMKLFAELEIKRKEREAK-EMHERKRQREEEIEAQEKAKREREW 208 E ++ Y++ +K E+E K+++RE + E ER+R+ E + ++++ W Sbjct: 839 ----EELRE--YQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRW 890 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 53.9 bits (128), Expect = 1e-07 Identities = 39/192 (20%), Positives = 100/192 (52%), Gaps = 12/192 (6%) Query: 67 EVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAG 126 E DEE +R L + + + ++ Q+ E D+ ++ ++E +KR V++ Sbjct: 203 EFPDEEQLRRRELLEL-----RRKGREEKQQQRRERQDRVFQEEEEKEWRKRET-VLRKE 256 Query: 127 KEYVEHTVKERKKQLKKEGKPTI-VEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEM 185 +E ++ +R+++L++E + +E + +Q +Q +L E +++RK+ E + Sbjct: 257 EEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERRE 316 Query: 186 HERKRQREEEIEAQEKAKREREWQKNFEESRDGRV-----DSWRNFQANTKGKKEKKNRT 240 + +R+ ++E Q++ +RE++ ++ EE R+ ++ + R Q + ++E++ + Sbjct: 317 QQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQ 376 Query: 241 FLRPPKVKMEQR 252 R +++ EQ+ Sbjct: 377 LRREQQLRREQQ 388 Score = 51.6 bits (122), Expect = 6e-07 Identities = 43/185 (23%), Positives = 90/185 (48%), Gaps = 7/185 (3%) Query: 70 DEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEY 129 D+E ++R R L + + Q + Q E ++ + L QE+++R +++ ++ Sbjct: 479 DQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQL 538 Query: 130 VEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERK 189 + R++ LK+E + + +E + K+ ++ +L E +R++R +E ER Sbjct: 539 RREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERL 598 Query: 190 RQR--EEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKV 247 QR EE+E E+ +R RE + EE + R R ++ ++E++ + R + Sbjct: 599 EQRLKREEVERLEQEER-REQRLKREEPEEER----RQQLLKSEEQEERRQQQLRREQQE 653 Query: 248 KMEQR 252 + EQR Sbjct: 654 RREQR 658 Score = 49.3 bits (116), Expect = 3e-06 Identities = 53/241 (21%), Positives = 110/241 (45%), Gaps = 35/241 (14%) Query: 28 KQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPD 87 +Q E+R+ L + + ERL + L + L+ + E E++ KR + Sbjct: 510 EQEERREQRLKRQEEEERLQQ------RLRSEQQLRREQEERREQLLKR--------EEE 555 Query: 88 KNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVK----------ER 137 K + R Q+ ++ LL +E+++R + + +E +E +K ER Sbjct: 556 KRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEER 615 Query: 138 KKQLKKEGKPT------IVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQ 191 ++Q K +P +++ ++ E +Q ++ + E +KR+E E + KR+ Sbjct: 616 REQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE 675 Query: 192 REEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQ 251 EEE QE A+ E+E + E R+ W+ +Q ++ ++++ + RP K + ++ Sbjct: 676 HEEERREQELAEEEQEQAR---ERIKSRIPKWQ-WQLESEA-DARQSKVYSRPRKQEGQR 730 Query: 252 R 252 R Sbjct: 731 R 731 Score = 48.1 bits (113), Expect = 7e-06 Identities = 44/187 (23%), Positives = 90/187 (48%), Gaps = 34/187 (18%) Query: 70 DEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEY 129 +E++++R R + D Q+D +R + + D+ ++ L++E+K+R + Y Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTL------Y 890 Query: 130 VEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERK 189 + ++E QL+KE + +++E++ EL +R+ERE + E++ Sbjct: 891 AKPALQE---QLRKEQQ--LLQEEEEEL------------------QREEREKRRRQEQE 927 Query: 190 RQREEEIEAQEK----AKREREWQKNFEESRDGRVD-SWRNFQANTKGKKEKKNRTFLRP 244 RQ EE + Q++ + ERE ++ E R R D + + G++ +K R R Sbjct: 928 RQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987 Query: 245 PKVKMEQ 251 K + E+ Sbjct: 988 KKYREEE 994 Score = 47.4 bits (111), Expect = 1e-05 Identities = 39/194 (20%), Positives = 96/194 (49%), Gaps = 10/194 (5%) Query: 70 DEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKR--------ALD 121 +EE+++ QL + + + +R + E + + + LL +E +KR + Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112 Query: 122 VIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKERE 181 + +E + +ER+K+ ++E + EE++ + ++ + ++ + E++R+ RE Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172 Query: 182 AKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWR--NFQANTKGKKEKKNR 239 +E+ + + Q E + + + +RER++++ E R R +R + +++ K + E + Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232 Query: 240 TFLRPPKVKMEQRE 253 +R KV + RE Sbjct: 1233 NAVRDNKVYCKGRE 1246 Score = 45.4 bits (106), Expect = 5e-05 Identities = 42/186 (22%), Positives = 90/186 (48%), Gaps = 11/186 (5%) Query: 70 DEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEY 129 ++E ++R +QL + Q++ R Q+ + L +EQ+ R ++ ++ Sbjct: 354 EQEEERREQQLR------REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 407 Query: 130 VEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKR---KEREAKEMH 186 R++QL++E + +E++ K ++ +L E E +R K E E H Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467 Query: 187 ERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPK 246 E++R++++ QE+ +RER W K EE R + + R Q + ++ ++ R + + Sbjct: 468 EQERRKQQLKRDQEEERRER-WLKLEEEERREQQER-REQQLRREQEERREQRLKRQEEE 525 Query: 247 VKMEQR 252 +++QR Sbjct: 526 ERLQQR 531 Score = 45.4 bits (106), Expect = 5e-05 Identities = 37/189 (19%), Positives = 93/189 (49%), Gaps = 13/189 (6%) Query: 62 LQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAV--------DKAYKLLLDQ 113 LQ + ++ +E++++FR+ L + + + R Q+ + + ++ + L Q Sbjct: 1710 LQEEQQLRRQELERKFREEEQL--RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQ 1767 Query: 114 EQKKRALDVIQAGKEYVEHTVKERKKQLK-KEGKPTIVEEDDPELFKQAVYKQTMKLFAE 172 E+ ++ + Q +E E ++ ++ K +E + E ++ +L Q + + Sbjct: 1768 ERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQ 1827 Query: 173 LEIKRKEREAKEMHERKRQREEEIEAQEKAKRERE--WQKNFEESRDGRVDSWRNFQANT 230 L+++ +E+ ++ +R+ + EE+ QEK++RE + WQ+ ++ R R R Sbjct: 1828 LQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRR 1887 Query: 231 KGKKEKKNR 239 + K+E+++R Sbjct: 1888 QQKEEQRHR 1896 Score = 43.5 bits (101), Expect = 2e-04 Identities = 39/184 (21%), Positives = 85/184 (46%), Gaps = 9/184 (4%) Query: 70 DEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEY 129 +E++++ QL + + + +R + + + + + LL +E +KR + Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992 Query: 130 VEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERK 189 E +E ++ L++E + +E + + K+ +Q E ++ R+ERE + + ER+ Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE-----EEQLLREEREKRRLQERE 1047 Query: 190 RQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKM 249 RQ EE E Q+ E E E R + R ++ + ++E++ P K + Sbjct: 1048 RQYREEEELQQ----EEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRR 1103 Query: 250 EQRE 253 ++RE Sbjct: 1104 QERE 1107 Score = 43.5 bits (101), Expect = 2e-04 Identities = 43/225 (19%), Positives = 102/225 (45%), Gaps = 11/225 (4%) Query: 17 EEAFMTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKR 76 +E F E +Q+ +++ + Q R P + E Q+ + + + Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLE----EEQQLHRQQRQRKFLQE 1536 Query: 77 FRQLSILVHPDKNQDDADRAQKAFEAVDKA---YKLLLDQEQKKRALDVIQAGKEYVEHT 133 +QL + + D DR + E + + +L + +K L+ + ++ E Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK 1596 Query: 134 VKERKKQLKK-EGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQR 192 E ++QL++ EG+ + +E D + + +Q ++ E ++ R+ER+ K + E + R Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFRED---EQLLQEREEQQLHRQERDRKFLEEEPQLR 1653 Query: 193 EEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKK 237 +E E Q + R+R++++ + ++G R + + K ++E++ Sbjct: 1654 RQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ 1698 Score = 42.7 bits (99), Expect = 3e-04 Identities = 51/226 (22%), Positives = 104/226 (46%), Gaps = 26/226 (11%) Query: 31 EKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQ 90 E+R+ L + Q+ R + L + L+ + ++ E+ +R +QL + Q Sbjct: 371 ERREQQLRREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 429 Query: 91 DDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIV 150 ++ +R ++ E + +L +QE+++ D ++ +E H + RK+QLK++ Sbjct: 430 EE-ERHEQKHEQERREQRLKREQEERR---DWLKREEETERHEQERRKQQLKRDQ----- 480 Query: 151 EEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQ---REEEIEAQEKAKRERE 207 EE+ E + L E E +R+++E +E R+ Q RE+ ++ QE+ E Sbjct: 481 EEERRERW----------LKLEEEERREQQERREQQLRREQEERREQRLKRQEE---EER 527 Query: 208 WQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQRE 253 Q+ + R + + K ++EK+ R ++K EQ E Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573 Score = 42.0 bits (97), Expect = 5e-04 Identities = 34/195 (17%), Positives = 97/195 (49%), Gaps = 15/195 (7%) Query: 70 DEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAG--- 126 +EE + R R+ + +K Q++ + Q+ + ++ + L QE ++ + Q Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300 Query: 127 --------KEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRK 178 K+ E ++ +++ ++E + E + +L ++ ++ +L E E +R+ Sbjct: 301 RREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERR 360 Query: 179 EREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKN 238 E++ + E +R RE+++ +++ +RE++ ++ + R+ ++ + + + ++E++ Sbjct: 361 EQQLRREQEEER-REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 419 Query: 239 RTFLRPPKVKMEQRE 253 R R +++ EQ E Sbjct: 420 R---REQQLRREQEE 431 Score = 40.8 bits (94), Expect = 0.001 Identities = 30/166 (18%), Positives = 84/166 (50%), Gaps = 11/166 (6%) Query: 88 KNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKP 147 + Q++ Q+ E ++ + L +EQ++R ++ +E + R++QL++E + Sbjct: 316 EQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE-----ERREQQLRREQEE 370 Query: 148 TIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKRERE 207 E + +L ++ ++ +L E +++R+++ +E R RE+++ +++ +RE++ Sbjct: 371 ---ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR---REQQLRREQQLRREQQ 424 Query: 208 WQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQRE 253 ++ EE R + + K ++E++ R + + ++E Sbjct: 425 LRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470 Score = 40.8 bits (94), Expect = 0.001 Identities = 44/241 (18%), Positives = 115/241 (47%), Gaps = 14/241 (5%) Query: 24 YSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSIL 83 Y E +Q+++ + L + + +R + + + ++ Q + ++ EE +KR RQ Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDK-KLQQKEEQLLGEEPEKRRRQEREK 988 Query: 84 VHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYV------EHTVKER 137 + ++ + + Q E +K + +++ +K+ D +Q +E + + ++ER Sbjct: 989 KYREEEELQQEEEQLLREEREKRRRQEWERQYRKK--DELQQEEEQLLREEREKRRLQER 1046 Query: 138 KKQLKKEGKPTIVEE----DDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQ-R 192 ++Q ++E + EE ++ E ++ ++ + EL+ + ++ +E +R+RQ R Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106 Query: 193 EEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQR 252 E + +E+ ++E E E + R + R ++ + ++E++ P K + ++ Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166 Query: 253 E 253 E Sbjct: 1167 E 1167 Score = 40.8 bits (94), Expect = 0.001 Identities = 51/252 (20%), Positives = 116/252 (46%), Gaps = 27/252 (10%) Query: 26 EVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDE-----EIKKRFRQL 80 E ++ ++RD + Q+ER + + + E Q+ E +E E ++FR+ Sbjct: 1282 ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE 1341 Query: 81 SILVHPDKNQ----DDADRA--QKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTV 134 L+ + Q + DR ++ ++ K L ++++ +R + KE + Sbjct: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC 1401 Query: 135 KERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREE 194 +ER++QL+++ + E++ +L +Q ++ + E +++R+ERE K + E ++ R+E Sbjct: 1402 QEREQQLRQD-RDRKFREEEQQLSRQERDRKFRE--EEQQVRRQERERKFLEEEQQLRQE 1458 Query: 195 -------------EIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTF 241 E E Q+ ++ER+ + EE + R + R F+ +E + + Sbjct: 1459 RHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL 1518 Query: 242 LRPPKVKMEQRE 253 ++ +QR+ Sbjct: 1519 EEEQQLHRQQRQ 1530 Score = 40.4 bits (93), Expect = 0.001 Identities = 35/142 (24%), Positives = 75/142 (52%), Gaps = 12/142 (8%) Query: 113 QEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAE 172 Q+Q++ D + +E E ++R+ L+KE + EE + Q +Q KL E Sbjct: 227 QQQRRERQDRVFQEEE--EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL--E 282 Query: 173 LEIKRKEREAKEMHERKRQREEEI-EAQEKAKREREWQKNFEESRDGRVDSWRNFQANTK 231 + R+ER+ +E +++ +RE+++ QE+ +RE++ ++ ++ R + + R Q Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQL--- 339 Query: 232 GKKEKKNRTFLRPPKVKMEQRE 253 ++E++ R R +++ EQ E Sbjct: 340 -RREQEER---REQQLRREQEE 357 Score = 40.4 bits (93), Expect = 0.001 Identities = 39/182 (21%), Positives = 91/182 (50%), Gaps = 11/182 (6%) Query: 70 DEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAV--DKAYKLLLDQEQKKRALDVIQAGK 127 +++++++ R+ L + + + R + E + ++ + L QE+ ++ L+ Q + Sbjct: 1436 EQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR 1495 Query: 128 EYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHE 187 E K R+++L+ + E++ +L +Q +Q L E +++R+ER + + Sbjct: 1496 RQ-ERDRKFREQELRSQEPERKFLEEEQQLHRQQ--RQRKFLQEEQQLRRQERGQQRRQD 1552 Query: 188 RKRQ-REEEI-----EAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTF 241 R R+ REEE E Q+ +++ER+ + EE + R + R F + + + ++ + Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ 1612 Query: 242 LR 243 LR Sbjct: 1613 LR 1614 Score = 39.3 bits (90), Expect = 0.003 Identities = 31/153 (20%), Positives = 77/153 (50%), Gaps = 8/153 (5%) Query: 108 KLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEE--DDPELFKQAVYKQ 165 +L +QE+++R + + +E R++QL++E + ++ + +L ++ ++ Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 409 Query: 166 TMKLFAELEIKRKER----EAKEMHERKRQREEEIEAQEKAKRE-REWQKNFEESRDGRV 220 +L E +++R+++ + +E HE+K ++E + ++ + E R+W K EE + Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKR-EEETERHE 468 Query: 221 DSWRNFQANTKGKKEKKNRTFLRPPKVKMEQRE 253 R Q ++E++ R + + EQ+E Sbjct: 469 QERRKQQLKRDQEEERRERWLKLEEEERREQQE 501 Score = 39.3 bits (90), Expect = 0.003 Identities = 33/183 (18%), Positives = 93/183 (50%), Gaps = 12/183 (6%) Query: 71 EEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYV 130 +E ++FR+ L+ ++ + R ++ + +++ +L + +++ D + +E Sbjct: 1615 QERDRKFREDEQLLQ-EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEE 1673 Query: 131 EHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKR 190 + + ++QL+++ + E++ +L +Q ++ L E +++R+E E K E + Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQE--RERKFLQEEQQLRRQELERKFREEEQL 1731 Query: 191 QREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKME 250 ++E E QE+ +R+ ++K EE + R + + ++++++R F +++ E Sbjct: 1732 RQETE---QEQLRRQERYRKILEE------EQLRPEREEQQLRRQERDRKFREEEQLRQE 1782 Query: 251 QRE 253 + E Sbjct: 1783 REE 1785 Score = 38.9 bits (89), Expect = 0.004 Identities = 35/186 (18%), Positives = 87/186 (46%), Gaps = 10/186 (5%) Query: 70 DEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEY 129 +EE+++ QL + +K + + +R + E + + + +++ +R+ D+ + Sbjct: 1173 EEELQQEEEQL-LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRS-DLKWQWEPE 1230 Query: 130 VEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERK 189 E+ V++ K K + +D +L + + L E + + +E+E + +R Sbjct: 1231 KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRD 1290 Query: 190 RQ--REEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKV 247 R EE++E +E+ + +R +K+ EE + R + K ++++ +R F ++ Sbjct: 1291 RHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREER------EEKRRRQETDRKFREEEQL 1344 Query: 248 KMEQRE 253 E+ E Sbjct: 1345 LQEREE 1350 Score = 38.9 bits (89), Expect = 0.004 Identities = 29/166 (17%), Positives = 88/166 (53%), Gaps = 9/166 (5%) Query: 94 DRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEED 153 +R Q+ D+ ++ ++EQ + + Q ++ + +E ++QL+++ + ++ Sbjct: 1656 EREQQLRHDRDRKFR---EEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQE 1712 Query: 154 DPELFKQAV---YKQTMKLFAELE---IKRKEREAKEMHERKRQREEEIEAQEKAKRERE 207 + +L +Q + +++ +L E E ++R+ER K + E + + E E + + +R+R+ Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772 Query: 208 WQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQRE 253 +++ + ++ R+ +++ K ++E++ R +++ +QR+ Sbjct: 1773 FREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRD 1818 Score = 38.1 bits (87), Expect = 0.007 Identities = 42/171 (24%), Positives = 82/171 (47%), Gaps = 22/171 (12%) Query: 96 AQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDP 155 AQ + A+ +A L D+E++ R GKE + ++ + Q + E + +EE+ Sbjct: 82 AQACYYALGQATGL--DEEKRARC-----DGKESLLQDRRQEEDQRRFEPRDRQLEEEPG 134 Query: 156 ELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEES 215 + +Q +Q +L AE E + +++E E +R+R R+EE+ Q + +ERE ++ EE Sbjct: 135 QRRRQKRQEQEREL-AEGEEQSEKQERLEQRDRQR-RDEELWRQRQEWQEREERRAEEEQ 192 Query: 216 -------------RDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQRE 253 + ++ + KG++EK+ + R +V E+ E Sbjct: 193 LQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE 243 Score = 37.4 bits (85), Expect = 0.013 Identities = 45/193 (23%), Positives = 91/193 (47%), Gaps = 21/193 (10%) Query: 71 EEIKKRF----RQLSILVHPDKNQDDADRAQKAFEAVDKAYKL--LLDQEQKKRALDVIQ 124 EE ++RF RQL + Q ++ ++ E +++ K L +++++R ++ + Sbjct: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175 Query: 125 AGKEYVEHTVKERKKQLKKEGKPTIVEE--DDPELFKQAVYKQTMKLFAELEIKRKEREA 182 +E+ E + +++ + K EE D+ +L ++ + LE++RK RE Sbjct: 176 QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRREL----------LELRRKGREE 225 Query: 183 KEMHERKRQRE--EEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRT 240 K+ R+RQ +E E +E KRE +K E+ ++ R Q + + K R Sbjct: 226 KQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE-QLRKLERQ 284 Query: 241 FLRPPKVKMEQRE 253 LR + + EQ++ Sbjct: 285 ELRRERQEEEQQQ 297 Score = 37.4 bits (85), Expect = 0.013 Identities = 36/185 (19%), Positives = 88/185 (47%), Gaps = 17/185 (9%) Query: 71 EEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYV 130 +E ++FR+ L H ++ + + Q+ + + L +EQ+ R + Q ++ Sbjct: 1356 QERDRKFREEE-LRHQEQGRKFLEEEQRLRR--QERERKFLKEEQQLRCQEREQQLRQDR 1412 Query: 131 EHTVKERKKQLKKEGKPTIVEEDDPELFKQA-----------VYKQTMKLFAELEIKRKE 179 + +E ++QL ++ + E++ ++ +Q + ++ + F E E +E Sbjct: 1413 DRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQE 1472 Query: 180 REAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNF-QANTKGKKEKKN 238 RE +++H ++R R+ E Q+ ++ER+ + F E + R F + + ++++ Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERD--RKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530 Query: 239 RTFLR 243 R FL+ Sbjct: 1531 RKFLQ 1535 Score = 35.4 bits (80), Expect = 0.048 Identities = 48/246 (19%), Positives = 108/246 (43%), Gaps = 40/246 (16%) Query: 29 QIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDK 88 Q ++RD + + ER R + Y E L+ + ++ EE ++ R+ + Sbjct: 866 QEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE----EREKR 921 Query: 89 NQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPT 148 + + +R + E + + + LL +E++KR +ER++Q +K+ K Sbjct: 922 RRQEQERQYREEEQLQQEEEQLLREEREKRRR--------------QERERQYRKDKKLQ 967 Query: 149 IVEE----DDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKR-------------- 190 EE ++PE ++ ++ + EL+ + ++ +E +R+R Sbjct: 968 QKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQ 1027 Query: 191 QREEEIEAQEKAKR---EREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKV 247 Q EE++ +E+ KR ERE Q EE + + T+ ++++ R + + ++ Sbjct: 1028 QEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR-RRQELERQYRKEEEL 1086 Query: 248 KMEQRE 253 + E+ + Sbjct: 1087 QQEEEQ 1092 Score = 34.7 bits (78), Expect = 0.082 Identities = 43/227 (18%), Positives = 90/227 (39%), Gaps = 29/227 (12%) Query: 28 KQIEKRDSVLTSKNQIERLTR--PGSSYFNLNPFEVLQIDPEVTDEEIKKRF-------- 77 +Q E+R+ L + + ERL + E+ + + E E IK R Sbjct: 650 EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLE 709 Query: 78 -----RQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEH 132 RQ + P K + R ++ +E+++R +Q +E H Sbjct: 710 SEADARQSKVYSRPRKQEGQRRRQEQ--------------EEKRRRRESELQWQEEERAH 755 Query: 133 TVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQR 192 ++ ++Q + EE ++ + ++ E +++ +ER+ +E + Sbjct: 756 RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEE 815 Query: 193 EEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNR 239 E+E +++ +RE+E Q EE + R + + Q G +E + R Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQER 862 Score = 33.9 bits (76), Expect = 0.14 Identities = 37/197 (18%), Positives = 89/197 (45%), Gaps = 13/197 (6%) Query: 26 EVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVH 85 E +Q+ + + + ++ER R ++L+ + E +E ++++R+ L Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEE-LQQEEEQLLREEQEKRRQERERQYREEEELQR 1207 Query: 86 PDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKE------YVEHTVKERKK 139 + Q D Q++ D ++ ++E R V G+E + +++R+ Sbjct: 1208 QKRKQRYRDEDQRS----DLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQS 1263 Query: 140 QLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEI--E 197 Q + +E D E ++ ++ E +++R+E++ + +RK Q E+++ E Sbjct: 1264 QQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLRE 1323 Query: 198 AQEKAKREREWQKNFEE 214 +E+ +R +E + F E Sbjct: 1324 EREEKRRRQETDRKFRE 1340 Score = 33.1 bits (74), Expect = 0.24 Identities = 30/145 (20%), Positives = 72/145 (49%), Gaps = 9/145 (6%) Query: 63 QIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKL--LLDQEQKKRAL 120 Q+ PE +++++++ R Q+ ++ ++ E+ D+ ++ L QE++++ L Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES-DRKFREEEQLRQEREEQQL 1812 Query: 121 DVIQAGKEY---VEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKR 177 Q +Y E E ++Q ++ + ++ ++ ++ +L+ E E KR Sbjct: 1813 RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKR 1872 Query: 178 K---EREAKEMHERKRQREEEIEAQ 199 + ER+ +E H R++Q+EE+ Q Sbjct: 1873 RQERERKLREEHIRRQQKEEQRHRQ 1897 >gi|68077168 DnaJ homology subfamily A member 5 isoform 1 [Homo sapiens] Length = 576 Score = 53.1 bits (126), Expect = 2e-07 Identities = 59/242 (24%), Positives = 102/242 (42%), Gaps = 53/242 (21%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLL-------- 110 +E L + + ++EE+KK +R+L++ HPDKN D+A A + F+ + AY +L Sbjct: 5 YEALGVRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAW 64 Query: 111 ------------LDQEQKKRALDVIQ----------AGKEYVEHTV-KERKKQLKKEGKP 147 D E + +LD+++ E +TV + + + KE Sbjct: 65 YDNHREALLKGGFDGEYQDDSLDLLRYFTVTCYSGYGDDEKGFYTVYRNVFEMIAKEELE 124 Query: 148 TIVEE--DDPELF--KQAVYKQ-------------TMKLFAELEIKRKEREAKEMHERKR 190 +++EE DD F Q+ Y T K FA E + R+A E++ Sbjct: 125 SVLEEEVDDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKE-EYDTRQASNRWEKRA 183 Query: 191 QREEEIEAQEKAKREREWQKN----FEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPK 246 +E + ++KA++E+ F RD RV + R +K +K R K Sbjct: 184 MEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQK 243 Query: 247 VK 248 +K Sbjct: 244 LK 245 >gi|68077166 DnaJ homology subfamily A member 5 isoform 2 [Homo sapiens] Length = 531 Score = 53.1 bits (126), Expect = 2e-07 Identities = 59/242 (24%), Positives = 102/242 (42%), Gaps = 53/242 (21%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLL-------- 110 +E L + + ++EE+KK +R+L++ HPDKN D+A A + F+ + AY +L Sbjct: 5 YEALGVRRDASEEELKKAYRKLALKWHPDKNLDNAAEAAEQFKLIQAAYDVLSDPQERAW 64 Query: 111 ------------LDQEQKKRALDVIQ----------AGKEYVEHTV-KERKKQLKKEGKP 147 D E + +LD+++ E +TV + + + KE Sbjct: 65 YDNHREALLKGGFDGEYQDDSLDLLRYFTVTCYSGYGDDEKGFYTVYRNVFEMIAKEELE 124 Query: 148 TIVEE--DDPELF--KQAVYKQ-------------TMKLFAELEIKRKEREAKEMHERKR 190 +++EE DD F Q+ Y T K FA E + R+A E++ Sbjct: 125 SVLEEEVDDFPTFGDSQSDYDTVVHPFYAYWQSFCTQKNFAWKE-EYDTRQASNRWEKRA 183 Query: 191 QREEEIEAQEKAKREREWQKN----FEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPK 246 +E + ++KA++E+ F RD RV + R +K +K R K Sbjct: 184 MEKENKKIRDKARKEKNELVRQLVAFIRKRDKRVQAHRKLVEEQNAEKARKAEEMRRQQK 243 Query: 247 VK 248 +K Sbjct: 244 LK 245 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 52.8 bits (125), Expect = 3e-07 Identities = 49/213 (23%), Positives = 107/213 (50%), Gaps = 29/213 (13%) Query: 65 DPEVTDEEIKKRFRQLSILVHPDKNQDDADRA---QKAFEAVDKAYKLLLDQEQKKRALD 121 + ++ ++E K R ++ + ++ ++ +R +K +E V+K + QEQ+K+ D Sbjct: 382 EKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD 441 Query: 122 VIQAGKEYVEHTVKERKKQLKKEGKP-------------TIVEEDDPELFKQAVYKQTMK 168 Q K E ++ER+K++++E + + E+++ E +Q + +Q K Sbjct: 442 --QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499 Query: 169 LFAELEIKRKEREAKEMHERKRQREEEIEAQEK------AKRERE---WQKNFEESRDGR 219 L+ + +++ +E + E E+ R +EE+ QEK RE+E W++ E+ RD Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRD-QEEMWGQEKKMWRQEKMREQEDQMWEQE-EKMRDQE 557 Query: 220 VDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQR 252 W + K +E++ +T+ + K++ E+R Sbjct: 558 QKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590 Score = 46.2 bits (108), Expect = 3e-05 Identities = 42/211 (19%), Positives = 105/211 (49%), Gaps = 23/211 (10%) Query: 60 EVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRA 119 E+ + + E+ ++E K R ++ + ++ ++ + ++ E + + K L +QE++ R Sbjct: 273 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELRE 332 Query: 120 LDVIQAGKEYVEHT-VKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRK 178 + KE E ++E+++Q++++ + +E+ ++ +++Q +L+ E E + + Sbjct: 333 QE-----KELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW-EQEKQMR 386 Query: 179 EREAK----------------EMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDS 222 E+E K E ER R++E+ E EK + E++ Q+ +++RD Sbjct: 387 EQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKM 446 Query: 223 WRNFQANTKGKKEKKNRTFLRPPKVKMEQRE 253 + + KK ++ +R + KM+++E Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQE 477 Score = 43.9 bits (102), Expect = 1e-04 Identities = 33/170 (19%), Positives = 84/170 (49%), Gaps = 6/170 (3%) Query: 72 EIKKRFRQLSILVHPDKNQDDADRA---QKAFEAVDKAYKLLLDQEQKKRALDVIQAGKE 128 E K++ + + +K Q+ ++ +K + + K DQE+ + + + K+ Sbjct: 662 EQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKK 721 Query: 129 YVEHTVKERKKQLKKEGKPTIVEEDDPELFKQA--VYKQTMKLFAELEIKRKEREAKEMH 186 E R+++ K + + ++E + E+++Q +++Q K++ + + ++ + E H Sbjct: 722 MREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE-H 780 Query: 187 ERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEK 236 E+ +++E+ E +EK + + E + EE G+ + R + G++EK Sbjct: 781 EKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEK 830 Score = 42.0 bits (97), Expect = 5e-04 Identities = 41/188 (21%), Positives = 89/188 (47%), Gaps = 11/188 (5%) Query: 71 EEIKKRFRQLSILVHPDKN---QDDADRAQKAF----EAVDKAYKLLLDQEQKKRALDVI 123 E+ +K +RQ L +K Q+ R QK E + + + + +QE+K R + Sbjct: 311 EQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEK 370 Query: 124 QAGKE---YVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKER 180 +E + + ++Q ++ + + E+D+ K+ ++ K++ ++E R+E+ Sbjct: 371 MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEK 430 Query: 181 EAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRT 240 + +E ++ R +EE+++ +E+ RERE + EE + Q ++E+K Sbjct: 431 KMQEQEKKTRDQEEKMQEEERI-REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 489 Query: 241 FLRPPKVK 248 R P+ K Sbjct: 490 QQRLPEQK 497 Score = 39.3 bits (90), Expect = 0.003 Identities = 37/194 (19%), Positives = 94/194 (48%), Gaps = 12/194 (6%) Query: 65 DPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQ 124 + ++ +EE R ++ + +K Q+ ++ + E + + + + +QE+K Q Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE----Q 650 Query: 125 AGKEYVEHTVKERKKQL---KKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKERE 181 K + + + E+K++L +K + ++E + ++++Q ++ K E E K ++E Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQ---EKMEKKTQEQEKKTWDQE 707 Query: 182 AKEMHERKRQREEEIEAQEKAKRERE--WQKNFEESRDGRVDSWRNFQANTKGKKEKKNR 239 E R+RE+++ +E+ RE+E Q+ E+ ++ + W + + +++ + Sbjct: 708 KMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQ 767 Query: 240 TFLRPPKVKMEQRE 253 L K K+ + E Sbjct: 768 QRLPEQKEKLWEHE 781 Score = 38.5 bits (88), Expect = 0.006 Identities = 40/181 (22%), Positives = 89/181 (49%), Gaps = 27/181 (14%) Query: 74 KKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQ---------EQKKRALDVIQ 124 KK +RQ +K ++ D+ + E + + + DQ EQ+K+ D Q Sbjct: 531 KKMWRQ-------EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWD--Q 581 Query: 125 AGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAK- 183 K E ++ER+K++++E + +E+ + ++ + +Q K++ E E K +E+E K Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW-EQEEKMQEQEEKM 640 Query: 184 -EMHERKRQREEEIEAQEKAKRERE--WQ----KNFEESRDGRVDSWRNFQANTKGKKEK 236 E E+ ++EE++ Q++ ++E W+ + E+ ++ W + K ++++ Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700 Query: 237 K 237 K Sbjct: 701 K 701 Score = 37.7 bits (86), Expect = 0.010 Identities = 31/158 (19%), Positives = 76/158 (48%), Gaps = 8/158 (5%) Query: 101 EAVDKAYKLLLDQEQKKRALDVI--QAGKEYVEHTVKERKKQLKKEGKPTIVEE----DD 154 E + + + + +QE+K R + + Q K + + ++E++ Q+ ++ + +E D Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563 Query: 155 PELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEE 214 E ++ +Q K + + E R+E +E ++ R+ EE + QE+ +E+E + +E Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE--EKMQE 621 Query: 215 SRDGRVDSWRNFQANTKGKKEKKNRTFLRPPKVKMEQR 252 + + Q + E++ + + + K+ +QR Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659 Score = 35.8 bits (81), Expect = 0.037 Identities = 32/185 (17%), Positives = 86/185 (46%), Gaps = 9/185 (4%) Query: 60 EVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRA 119 E ++ + + + E K R + + +K Q+ ++ Q+ E + + + + +QE+K Sbjct: 707 EKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWE 766 Query: 120 LDVIQAGKEYV--------EHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFA 171 + KE + + + E++++++ + + +E+ ++ + Q K++ Sbjct: 767 QQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWG 826 Query: 172 ELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTK 231 + E K +E K + ++ +E + +EK + + E + EE G+ + R + + Sbjct: 827 QEE-KMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885 Query: 232 GKKEK 236 G++EK Sbjct: 886 GQEEK 890 Score = 34.7 bits (78), Expect = 0.082 Identities = 31/151 (20%), Positives = 74/151 (49%), Gaps = 7/151 (4%) Query: 87 DKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGK 146 +K D ++ ++ ++ K+ ++E + + +Q +E ++ +E +Q +K Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK--- 756 Query: 147 PTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQ-EKAKRE 205 + E+++ +Q + +Q KL+ E E +++ + E E+ R +EE++ Q EK + + Sbjct: 757 --MWEQEEKMWEQQRLPEQKEKLW-EHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQ 813 Query: 206 REWQKNFEESRDGRVDSWRNFQANTKGKKEK 236 E + EE G+ + + G++EK Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEK 844 Score = 33.1 bits (74), Expect = 0.24 Identities = 45/194 (23%), Positives = 80/194 (41%), Gaps = 32/194 (16%) Query: 86 PDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEG 145 P +++D A R ++ + + L + + D Y+E KER + Sbjct: 161 PGESKDLAGRLHHSWHFAGELQRALSAVSTRHKKAD------RYIEELTKERDALSLELY 214 Query: 146 KPTIVEED----DPELFKQAVYKQTMKLFAEL---EIKRKEREAK---------EMHERK 189 + TI E+ + EL ++ ++ K +L E+KRK AK + E Sbjct: 215 RNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEM 274 Query: 190 RQREEEIEAQEKAKRERE---WQKNFE------ESRDGRVDSWRNFQANTKGKKE-KKNR 239 ++EEE+ QEK R++E W++ + R+ WR + + +KE ++ Sbjct: 275 WRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQE 334 Query: 240 TFLRPPKVKMEQRE 253 LR K EQ E Sbjct: 335 KELREQKELREQEE 348 >gi|47777312 DnaJ (Hsp40) homolog, subfamily B, member 3 [Homo sapiens] Length = 145 Score = 51.6 bits (122), Expect = 6e-07 Identities = 21/58 (36%), Positives = 41/58 (70%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQK 116 +EVL + + + E IKK +R+L++ HPDKN ++ + A++ F+ V +AY++L D +++ Sbjct: 5 YEVLDVPRQASSEAIKKAYRKLALKWHPDKNPENKEEAERRFKQVAEAYEVLSDAKKR 62 >gi|17388799 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform a [Homo sapiens] Length = 326 Score = 51.2 bits (121), Expect = 8e-07 Identities = 21/58 (36%), Positives = 41/58 (70%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQK 116 +EVL + + E+IKK +R+L++ HPDKN ++ + A++ F+ V +AY++L D +++ Sbjct: 5 YEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKR 62 >gi|4885495 DnaJ (Hsp40) homolog, subfamily B, member 6 isoform b [Homo sapiens] Length = 241 Score = 51.2 bits (121), Expect = 8e-07 Identities = 21/58 (36%), Positives = 41/58 (70%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQK 116 +EVL + + E+IKK +R+L++ HPDKN ++ + A++ F+ V +AY++L D +++ Sbjct: 5 YEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKR 62 >gi|194328760 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 2 [Homo sapiens] Length = 397 Score = 50.4 bits (119), Expect = 1e-06 Identities = 24/70 (34%), Positives = 44/70 (62%), Gaps = 8/70 (11%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKR 118 +++L + P + EEIKK +R+L++ HPDKN D+ ++ F+ + +AY++L D +++ Sbjct: 8 YDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEK----FKLISQAYEVLSDPKKR-- 61 Query: 119 ALDVIQAGKE 128 DV G E Sbjct: 62 --DVYDQGGE 69 >gi|194328758 DnaJ (Hsp40) homolog, subfamily A, member 4 isoform 1 [Homo sapiens] Length = 426 Score = 50.4 bits (119), Expect = 1e-06 Identities = 24/70 (34%), Positives = 44/70 (62%), Gaps = 8/70 (11%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKR 118 +++L + P + EEIKK +R+L++ HPDKN D+ ++ F+ + +AY++L D +++ Sbjct: 37 YDILGVKPSASPEEIKKAYRKLALKYHPDKNPDEGEK----FKLISQAYEVLSDPKKR-- 90 Query: 119 ALDVIQAGKE 128 DV G E Sbjct: 91 --DVYDQGGE 98 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 50.1 bits (118), Expect = 2e-06 Identities = 33/185 (17%), Positives = 93/185 (50%), Gaps = 2/185 (1%) Query: 71 EEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEY- 129 +E+K++ + +L+ + Q +AD K ++V + +++ + L+ Q K + Sbjct: 233 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 292 Query: 130 VEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERK 189 E ++ER+++++++ + +E+ ++ ++++ K+ + E+ ++ E E K Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352 Query: 190 RQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQ-ANTKGKKEKKNRTFLRPPKVK 248 +E+I QE+ ++E E + E+ ++ WR + + +K ++ ++ + K Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412 Query: 249 MEQRE 253 M ++E Sbjct: 413 MGEQE 417 Score = 46.6 bits (109), Expect = 2e-05 Identities = 36/190 (18%), Positives = 97/190 (51%), Gaps = 9/190 (4%) Query: 68 VTDEEIKKRFRQLS-ILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAG 126 + ++ +K +RQ I +K Q+ ++ ++ E + + +++ ++E+K R + + Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341 Query: 127 KEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMH 186 K E ++E ++++ ++ K I E+++ ++ + +Q + E ++ R+E + +E Sbjct: 342 K---EEKIRELEEKMHEQEK--IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 396 Query: 187 ERKRQREEEIEAQEKAKRERE---WQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLR 243 E+ R++EE ++ QE+ E+E W++ E + + + KK ++ +R Sbjct: 397 EKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIR 456 Query: 244 PPKVKMEQRE 253 + M+++E Sbjct: 457 EQEEMMQEQE 466 Score = 44.3 bits (103), Expect = 1e-04 Identities = 44/200 (22%), Positives = 95/200 (47%), Gaps = 22/200 (11%) Query: 70 DEEIKKRFRQLSILVHPDKNQDDADRAQKAF-----EAVDKAYKLLLDQEQKKRALDVI- 123 +E+I++R ++ + Q++ R Q+ E + + +++ ++E+K R L+ Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353 Query: 124 --------QAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEI 175 Q K E ++E++K+ ++E K EE E ++ ++ ++ E E Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE--QEEKIREQEEMMQEQEE 411 Query: 176 KRKEREAK--EMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGK 233 K E+E K E E +++EE++ QE+ RE+E + +E + + Q G+ Sbjct: 412 KMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGE 471 Query: 234 KEKKNRTFLRPPKVKMEQRE 253 +E K + + KM+++E Sbjct: 472 QEGK----MCEQEAKMQEQE 487 Score = 43.1 bits (100), Expect = 2e-04 Identities = 43/248 (17%), Positives = 121/248 (48%), Gaps = 22/248 (8%) Query: 21 MTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQL 80 M + E K + + + + +I L + E + + E E+ K++ ++ Sbjct: 324 MMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA 383 Query: 81 SILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKK-RALDVIQAGKEYV---EHTVKE 136 + +K ++ ++ ++ E + + + + +QE+K + +Q +E + E ++E Sbjct: 384 KMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE 443 Query: 137 RKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFA--------ELEIKRKEREAKEMHER 188 ++K+++++ + +E+ + ++ + +Q K+ E +++R+E + +E ++ Sbjct: 444 QEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK 503 Query: 189 KRQREEEIEAQEKAKRERE---WQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPP 245 R++EE+I QE+ +E+E W++ EE + + + + + ++EK +R Sbjct: 504 IREQEEKIREQEEMMQEQEEKMWEQ--EEKMCEQEEKMQEQEEKMRRQEEK-----MREQ 556 Query: 246 KVKMEQRE 253 +V++ Q+E Sbjct: 557 EVRLRQQE 564 Score = 40.4 bits (93), Expect = 0.001 Identities = 34/169 (20%), Positives = 80/169 (47%), Gaps = 18/169 (10%) Query: 60 EVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRA 119 E++Q E E+ +K + Q ++ Q+ ++ ++ E + + K + +QE+K R Sbjct: 404 EMMQEQEEKMGEQEEKMWEQ------EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457 Query: 120 LDVI----------QAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKL 169 + + Q GK + + +++ + + I E++ ++ ++ ++ Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517 Query: 170 FAELEIKRKEREAK--EMHERKRQREEEIEAQEKAKREREWQKNFEESR 216 E E K E+E K E E+ +++EE++ QE+ RE+E + +E + Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEK 566 Score = 40.4 bits (93), Expect = 0.001 Identities = 28/147 (19%), Positives = 81/147 (55%), Gaps = 5/147 (3%) Query: 65 DPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDV-I 123 + E+ ++E K R ++ I K ++ ++ ++ E + + + + +QE K + + Sbjct: 424 EEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKM 483 Query: 124 QAGKEYV---EHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKER 180 Q +E + E ++E++K+++++ + +E+ + ++ +++Q K+ E E K +E+ Sbjct: 484 QEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKM-CEQEEKMQEQ 542 Query: 181 EAKEMHERKRQREEEIEAQEKAKRERE 207 E K + ++ RE+E+ +++ ++ +E Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKMQE 569 >gi|22749377 DnaJ (Hsp40) homolog, subfamily C, member 18 [Homo sapiens] Length = 358 Score = 50.1 bits (118), Expect = 2e-06 Identities = 38/143 (26%), Positives = 72/143 (50%), Gaps = 7/143 (4%) Query: 57 NPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQK 116 N +E+L + + +DEE+KK +R+L++ HPDKN A A AF+A+ A+ +L + +++ Sbjct: 82 NYYEILGVSRDASDEELKKAYRKLALKFHPDKN--CAPGATDAFKAIGNAFAVLSNPDKR 139 Query: 117 KRALDVIQAGKEYVEHTV-KERKKQLKKEGKPTIVEEDDPELFKQAVYKQ-TMKLFAELE 174 R + G E V T + R ++ + I E+ +F + + +F+ + Sbjct: 140 LR---YDEYGDEQVTFTAPRARPYNYYRDFEADITPEELFNVFFGGHFPTGNIHMFSNVT 196 Query: 175 IKRKEREAKEMHERKRQREEEIE 197 + HER + ++EE E Sbjct: 197 DDTYYYRRRHRHERTQTQKEEEE 219 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 50.1 bits (118), Expect = 2e-06 Identities = 37/147 (25%), Positives = 65/147 (44%), Gaps = 4/147 (2%) Query: 111 LDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLF 170 + E+ K+ + Q E H E + + + E + +E ++ E K K+ Sbjct: 233 ISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADER 292 Query: 171 AELEIKRK----EREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNF 226 A +E + K ERE +E ER+R REEE A E+ +R +E +K E R + + Sbjct: 293 ARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRA 352 Query: 227 QANTKGKKEKKNRTFLRPPKVKMEQRE 253 + KE++ R + + E+ E Sbjct: 353 AEERQRIKEEEKRAAEERQRARAEEEE 379 Score = 46.2 bits (108), Expect = 3e-05 Identities = 42/194 (21%), Positives = 85/194 (43%), Gaps = 18/194 (9%) Query: 63 QIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDV 122 QI E +E ++ I H ++D +RA+ A + L+ E+++R Sbjct: 232 QISSEEPKQEEEREQGSDEISHHEKMEEEDKERAE--------AERARLEAEERERI--- 280 Query: 123 IQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREA 182 K + + + + +++ E K E + E ++ ++ K AE + KE E Sbjct: 281 ----KAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEK 336 Query: 183 KEMHERKRQREEEIEAQEKAKREREWQKNFEESRD---GRVDSWRNFQANTKGKKEKKNR 239 + ER+R +EEE A E+ +R +E +K E R + + + K+ ++ + Sbjct: 337 RAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKK 396 Query: 240 TFLRPPKVKMEQRE 253 ++ K+K E+ E Sbjct: 397 HAMQETKIKGEKVE 410 Score = 37.4 bits (85), Expect = 0.013 Identities = 36/146 (24%), Positives = 65/146 (44%), Gaps = 6/146 (4%) Query: 113 QEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAE 172 +E++KRA + Q KE + +ER++ +K+E K E + ++ ++ + AE Sbjct: 318 REEEKRAAEERQRIKEEEKRAAEERQR-IKEEEKRAAEERQRIKEEEKRAAEERQRARAE 376 Query: 173 LEIKRK---EREAKEMHERKRQREEEIEAQEKA--KREREWQKNFEESRDGRVDSWRNFQ 227 E K K ++ K++ E+K +E EK K E +W + D + Q Sbjct: 377 EEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQ 436 Query: 228 ANTKGKKEKKNRTFLRPPKVKMEQRE 253 KG K + R L+ K ++ E Sbjct: 437 GEEKGTKVQAKREKLQEDKPTFKKEE 462 Score = 36.2 bits (82), Expect = 0.028 Identities = 38/186 (20%), Positives = 74/186 (39%), Gaps = 22/186 (11%) Query: 65 DPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQ 124 D E E ++R RQ + + Q++ Q + A + D+E K + Sbjct: 33 DEEEAARERRRRARQERLR----QKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQV 88 Query: 125 AGKE---YVEHTVK-ERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKER 180 G + ++E + E ++Q + + +E DP + ++ + ++ + E Sbjct: 89 EGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRM----QNDTAEN 144 Query: 181 EAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRT 240 E E E+ R+E E +E + +QKN WR+ + N K KEK+ Sbjct: 145 ETTEKEEKSESRQERYEIEETETVTKSYQKN----------DWRDAEENKKEDKEKEEEE 194 Query: 241 FLRPPK 246 +P + Sbjct: 195 EEKPKR 200 Score = 32.7 bits (73), Expect = 0.31 Identities = 25/87 (28%), Positives = 48/87 (55%), Gaps = 5/87 (5%) Query: 136 ERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEE 195 +R ++L++ T E ++ E KQ + ++L EL+ KR+ER +++ E + QR ++ Sbjct: 534 KRLEELRRRRGET--ESEEFEKLKQKQQEAALEL-EELKKKREER--RKVLEEEEQRRKQ 588 Query: 196 IEAQEKAKREREWQKNFEESRDGRVDS 222 EA K + E E ++ EE R ++ Sbjct: 589 EEADRKLREEEEKRRLKEEIERRRAEA 615 Score = 28.9 bits (63), Expect = 4.5 Identities = 29/139 (20%), Positives = 62/139 (44%), Gaps = 18/139 (12%) Query: 114 EQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVE----EDDPELFKQAVYKQTMKL 169 ++KK +V E++ H +K + + G V+ E P++ ++ + Sbjct: 483 DRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRR 542 Query: 170 FAELE------IKRKEREA--------KEMHERKRQREEEIEAQEKAKREREWQKNFEES 215 E E +K+K++EA K+ ER++ EEE + +++ + +R+ ++ E+ Sbjct: 543 RGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKR 602 Query: 216 RDGRVDSWRNFQANTKGKK 234 R R +A K +K Sbjct: 603 RLKEEIERRRAEAAEKRQK 621 >gi|21361912 DnaJ (Hsp40) homolog, subfamily C, member 1 [Homo sapiens] Length = 554 Score = 49.7 bits (117), Expect = 2e-06 Identities = 23/71 (32%), Positives = 45/71 (63%), Gaps = 2/71 (2%) Query: 56 LNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQ 115 LN ++ L + + + +I+K +R+LS+ +HPDKN+D + A+ F + Y++L D E+ Sbjct: 64 LNFYQFLGVQQDASSADIRKAYRKLSLTLHPDKNKD--ENAETQFRQLVAIYEVLKDDER 121 Query: 116 KKRALDVIQAG 126 ++R D++ G Sbjct: 122 RQRYDDILING 132 >gi|194306642 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo sapiens] Length = 409 Score = 49.7 bits (117), Expect = 2e-06 Identities = 23/60 (38%), Positives = 41/60 (68%), Gaps = 2/60 (3%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKR 118 +E+L + +DE++KK +R+L++ HPDKN A A +AF+A+ AY +L + E++K+ Sbjct: 146 YEILGVSRGASDEDLKKAYRRLALKFHPDKNH--APGATEAFKAIGTAYAVLSNPEKRKQ 203 >gi|194306640 DnaJ (Hsp40) homolog, subfamily B, member 12 [Homo sapiens] Length = 409 Score = 49.7 bits (117), Expect = 2e-06 Identities = 23/60 (38%), Positives = 41/60 (68%), Gaps = 2/60 (3%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKR 118 +E+L + +DE++KK +R+L++ HPDKN A A +AF+A+ AY +L + E++K+ Sbjct: 146 YEILGVSRGASDEDLKKAYRRLALKFHPDKNH--APGATEAFKAIGTAYAVLSNPEKRKQ 203 >gi|4504511 DnaJ (Hsp40) homolog, subfamily A, member 1 [Homo sapiens] Length = 397 Score = 49.7 bits (117), Expect = 2e-06 Identities = 20/59 (33%), Positives = 41/59 (69%), Gaps = 4/59 (6%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKK 117 ++VL + P T EE+KK +R+L++ HPDKN ++ ++ F+ + +AY++L D ++++ Sbjct: 8 YDVLGVKPNATQEELKKAYRKLALKYHPDKNPNEGEK----FKQISQAYEVLSDAKKRE 62 >gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform a [Homo sapiens] Length = 277 Score = 49.7 bits (117), Expect = 2e-06 Identities = 20/59 (33%), Positives = 41/59 (69%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKK 117 +E+L + + ++IKK +R+ ++ HPDKN D+ + A+K F+ V +AY++L D+ +++ Sbjct: 5 YEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKRE 63 >gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform b [Homo sapiens] Length = 324 Score = 49.7 bits (117), Expect = 2e-06 Identities = 20/59 (33%), Positives = 41/59 (69%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKK 117 +E+L + + ++IKK +R+ ++ HPDKN D+ + A+K F+ V +AY++L D+ +++ Sbjct: 5 YEILDVPRSASADDIKKAYRRKALQWHPDKNPDNKEFAEKKFKEVAEAYEVLSDKHKRE 63 >gi|148839339 nexilin (F actin binding protein) [Homo sapiens] Length = 675 Score = 49.7 bits (117), Expect = 2e-06 Identities = 39/152 (25%), Positives = 72/152 (47%), Gaps = 11/152 (7%) Query: 71 EEIKKRFRQLSI-LVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEY 129 EE K+ F + +V+ D+ D + K + KL ++ +++R D + +E Sbjct: 275 EEEKRAFEEARRQMVNEDEENQDTAKIFKGYRP--GKLKLSFEEMERQRREDEKRKAEEE 332 Query: 130 VEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERK 189 ++E KK + + +V++D PE++K Q +LEI +E ++M E K Sbjct: 333 ARRRIEEEKKAFAEARRNMVVDDDSPEMYK--TISQEFLTPGKLEINFEELLKQKMEEEK 390 Query: 190 RQREEE------IEAQEKAKREREWQKNFEES 215 R+ EEE +E QE + +E + EE+ Sbjct: 391 RRTEEERKHKLEMEKQEFEQLRQEMGEEEEEN 422 Score = 44.3 bits (103), Expect = 1e-04 Identities = 39/123 (31%), Positives = 64/123 (52%), Gaps = 10/123 (8%) Query: 100 FEAVDKAYKLLLDQEQKKRALDVIQAGKE-YVEHTVKERKKQLKKEGKPTIVEEDDPELF 158 FEA+ +A ++ ++R+ D Q KE Y+ R+KQ KE + EED Sbjct: 35 FEAMQRAR----EERNQRRSRDEKQRRKEQYIREREWNRRKQEIKEMLASDDEEDVSSKV 90 Query: 159 KQAVYKQ---TMK-LFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEE 214 ++A + T+K FAE+E +R+E + K E +++R E+ + EK K +RE K E+ Sbjct: 91 EKAYVPKLTGTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQ-DMLEKRKIQRELAKRAEQ 149 Query: 215 SRD 217 D Sbjct: 150 IED 152 Score = 38.1 bits (87), Expect = 0.007 Identities = 49/221 (22%), Positives = 95/221 (42%), Gaps = 48/221 (21%) Query: 68 VTDEEIKKRFRQLSILVHPDKNQDDADRAQKAF---------------EAVDKAYKLLLD 112 + + E +R +++ ++ D +D + + +KA+ E + + Sbjct: 62 IREREWNRRKQEIKEMLASDDEEDVSSKVEKAYVPKLTGTVKGRFAEMEKQRQEEQRKRT 121 Query: 113 QEQKKRALDVIQAGKEYVEHTVKERKKQLK---KEGKPTIVEEDDPELFKQAV----YKQ 165 +E++KR ++ K ++ + +R +Q++ G + EE D L V YK Sbjct: 122 EEERKRRIEQDMLEKRKIQRELAKRAEQIEDINNTGTESASEEGDDSLLITVVPVKSYKT 181 Query: 166 TMKL---FAELEIKRKEREAKEMHERKRQREEE----------------IEAQEKAKRER 206 + K+ F +LE +R+E+E + E KR R EE E + +AK+E Sbjct: 182 SGKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQRPSLKEAKCLSLVMDDEIESEAKKES 241 Query: 207 ----EWQKNFEESRDGRVDSWRNFQANTKGKK--EKKNRTF 241 + + FEE R ++ R QA + +K E++ R F Sbjct: 242 LSPGKLKLTFEELERQRQEN-RKKQAEEEARKRLEEEKRAF 281 Score = 35.0 bits (79), Expect = 0.063 Identities = 35/163 (21%), Positives = 72/163 (44%), Gaps = 20/163 (12%) Query: 108 KLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTM 167 KL ++ +++R + + +E ++E K+ + E + +V ED+ ++K Sbjct: 248 KLTFEELERQRQENRKKQAEEEARKRLEEEKRAFE-EARRQMVNEDEENQDTAKIFKGYR 306 Query: 168 KLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRD---------- 217 +L + ER+ +E +RK + E +E+ K E ++N D Sbjct: 307 PGKLKLSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQ 366 Query: 218 -----GRVDSWRNFQANTKGK--KEKKNRTFLRPPKVKMEQRE 253 G+++ NF+ K K +EK+ R K++ME++E Sbjct: 367 EFLTPGKLEI--NFEELLKQKMEEEKRRTEEERKHKLEMEKQE 407 Score = 28.5 bits (62), Expect = 5.9 Identities = 46/214 (21%), Positives = 88/214 (41%), Gaps = 45/214 (21%) Query: 14 GSTEEAFMTFYSEVKQIEKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEE- 72 G E F + + EKR + K+++E + E Q+ E+ +EE Sbjct: 372 GKLEINFEELLKQKMEEEKRRTEEERKHKLE-----------MEKQEFEQLRQEMGEEEE 420 Query: 73 ------IKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAG 126 + + + +L L Q A + FE + + L +++ ++ ++ +A Sbjct: 421 ENETFGLSREYEELIKLKRSGSIQ--AKNLKSKFEKIGQ-----LSEKEIQKKIEEERAR 473 Query: 127 KEYVEHTVKERKKQLKKEGKPTIVEEDD----PELFKQA--VYKQTMKL-FAELEIKRKE 179 + ++ +KER+ + EEDD P +A +K MK F ++ R+E Sbjct: 474 RRAIDLEIKEREAE-------NFHEEDDVDVRPARKSEAPFTHKVNMKARFEQMAKAREE 526 Query: 180 REAKEMHERK------RQREEEIEAQEKAKRERE 207 E + + E+K QRE + Q+K + E E Sbjct: 527 EEQRRIEEQKLLRMQFEQREIDAALQKKREEEEE 560 >gi|72534740 DnaJ (Hsp40) homolog, subfamily B, member 14 isoform 1 [Homo sapiens] Length = 379 Score = 49.3 bits (116), Expect = 3e-06 Identities = 24/62 (38%), Positives = 40/62 (64%), Gaps = 2/62 (3%) Query: 57 NPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQK 116 N +EVL + + DE++KK +R+L++ HPDKN A A AF+ + AY +L + E++ Sbjct: 108 NYYEVLGVTKDAGDEDLKKAYRKLALKFHPDKNH--APGATDAFKKIGNAYAVLSNPEKR 165 Query: 117 KR 118 K+ Sbjct: 166 KQ 167 >gi|7706495 DnaJ (Hsp40) homolog, subfamily B, member 11 precursor [Homo sapiens] Length = 358 Score = 48.9 bits (115), Expect = 4e-06 Identities = 21/60 (35%), Positives = 43/60 (71%), Gaps = 1/60 (1%) Query: 59 FEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQDDADRAQKAFEAVDKAYKLLLDQEQKKR 118 +++L + + ++IKK +R+L++ +HPD+N DD +AQ+ F+ + AY++L D E++K+ Sbjct: 27 YKILGVPRSASIKDIKKAYRKLALQLHPDRNPDD-PQAQEKFQDLGAAYEVLSDSEKRKQ 85 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 48.9 bits (115), Expect = 4e-06 Identities = 43/191 (22%), Positives = 86/191 (45%), Gaps = 14/191 (7%) Query: 31 EKRDSVLTSKNQIERLTRPGSSYFNLNPFEVLQIDPEVTDEEIKKRFRQLSILVHPDKNQ 90 E+R ++ ER RP S P + E+ +E ++ R + D+ Sbjct: 623 ERRHGERDRRDNRERDQRPSS------PIRHQGRNDELERDERREERRVDRVDDRRDERA 676 Query: 91 DDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIV 150 + DR ++ ++ + D+E++K +E +ER+++ +KE Sbjct: 677 RERDRERERDRERERERERERDREREKE--------RELERERAREREREREKERDRERD 728 Query: 151 EEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQK 210 + D + ++ ++ + E E + +ERE + ER+R+RE E E + +ERE Q+ Sbjct: 729 RDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQR 788 Query: 211 NFEESRDGRVD 221 ++E+ GR D Sbjct: 789 DWEDKDKGRDD 799 Score = 43.1 bits (100), Expect = 2e-04 Identities = 32/153 (20%), Positives = 68/153 (44%), Gaps = 1/153 (0%) Query: 87 DKNQDDADRAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGK 146 D+ + D R ++ + VD + ++R D + +E +ER+K+ + E + Sbjct: 652 DELERDERREERRVDRVDDRRDERARERDRERERDR-ERERERERERDREREKERELERE 710 Query: 147 PTIVEEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMHERKRQREEEIEAQEKAKRER 206 E + E + + E E +R+ KE + +RE E E + + +RER Sbjct: 711 RAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERER 770 Query: 207 EWQKNFEESRDGRVDSWRNFQANTKGKKEKKNR 239 E ++ RD + R+++ KG+ +++ + Sbjct: 771 ERERERARERDKERERQRDWEDKDKGRDDRREK 803 Score = 40.4 bits (93), Expect = 0.001 Identities = 23/78 (29%), Positives = 42/78 (53%), Gaps = 1/78 (1%) Query: 176 KRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKE 235 + +ERE + +R+R++E E+E + +RERE +K + RD D R + + +E Sbjct: 687 RERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDRE 746 Query: 236 KKNRTFLRPPKVKMEQRE 253 K+ R R + + +RE Sbjct: 747 KE-REREREERERERERE 763 Score = 39.3 bits (90), Expect = 0.003 Identities = 30/148 (20%), Positives = 76/148 (51%), Gaps = 8/148 (5%) Query: 112 DQEQKKRALDVI-----QAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQT 166 D+ +++R +D + + +E ++R+++ ++E + E + EL ++ ++ Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716 Query: 167 MKLFAELEIKRKEREAKEMHERKRQREEEIEAQ-EKAKREREWQKNFEESRDGRVDSWRN 225 + E + + ++R+ ER+R+RE + E + E+ + ERE ++ E R+ + R Sbjct: 717 REREKERD-RERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 775 Query: 226 FQANTKGKKEKKNRTFLRPPKVKMEQRE 253 +A + K+ ++ R + K + ++RE Sbjct: 776 -RARERDKERERQRDWEDKDKGRDDRRE 802 Score = 32.7 bits (73), Expect = 0.31 Identities = 17/78 (21%), Positives = 38/78 (48%) Query: 176 KRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKE 235 +R + HER+ + + ++ ++ ERE++++ SRD R D + + ++ Sbjct: 404 ERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARD 463 Query: 236 KKNRTFLRPPKVKMEQRE 253 ++R LR + + RE Sbjct: 464 TRDRRELRDSRDMRDSRE 481 Score = 32.7 bits (73), Expect = 0.31 Identities = 21/127 (16%), Positives = 59/127 (46%), Gaps = 5/127 (3%) Query: 132 HTVKERKKQLKKEGKPTIV-----EEDDPELFKQAVYKQTMKLFAELEIKRKEREAKEMH 186 H ++R+ +++ +P+ D+ E ++ ++ ++ + + +ER+ + Sbjct: 626 HGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERER 685 Query: 187 ERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEKKNRTFLRPPK 246 +R+R+RE E E + ++ERE ++ R+ + R+ + + +++ + Sbjct: 686 DRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDR 745 Query: 247 VKMEQRE 253 K +RE Sbjct: 746 EKERERE 752 Score = 31.6 bits (70), Expect = 0.69 Identities = 17/64 (26%), Positives = 34/64 (53%), Gaps = 3/64 (4%) Query: 173 LEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKG 232 L + +ERE + + R+RE I + R+R+ + FE S +++S + +A +G Sbjct: 1340 LRERERERERDKRRDLDRERERLISDSVERDRDRDRDRTFESS---QIESVKRCEAKLEG 1396 Query: 233 KKEK 236 + E+ Sbjct: 1397 EHER 1400 Score = 30.0 bits (66), Expect = 2.0 Identities = 17/77 (22%), Positives = 37/77 (48%) Query: 177 RKEREAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDSWRNFQANTKGKKEK 236 RKE E++ + + E + EW+ N ++S +G ++ + + + K++K Sbjct: 113 RKESSRGRHREKEDIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQK 172 Query: 237 KNRTFLRPPKVKMEQRE 253 R ++ + ME+RE Sbjct: 173 IQRELMKLEQENMEKRE 189 >gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo sapiens] Length = 956 Score = 48.5 bits (114), Expect = 5e-06 Identities = 35/117 (29%), Positives = 64/117 (54%), Gaps = 2/117 (1%) Query: 95 RAQKAFEAVDKAYKLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDD 154 R Q+ E + K KL ++E+K++ + + KE + +E K+ +KE + +++ Sbjct: 336 RLQRDQERLGKQLKLRAEREEKEKLKEEAKRAKEEAKKKKEEEKELKEKERREKREKDEK 395 Query: 155 PELFKQAVYKQTMKLFAE-LEIKRKEREAKEMHERKRQREEEIEAQEKAKREREWQK 210 + KQ + ++ K E LE K +E+ KE +R R+ E+ I+A EKA+ R +QK Sbjct: 396 EKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLREEEKRIKA-EKAEITRFFQK 451 Score = 44.7 bits (104), Expect = 8e-05 Identities = 34/136 (25%), Positives = 74/136 (54%), Gaps = 23/136 (16%) Query: 127 KEYVEHTVKERKKQLKKE----GKPTIV--EEDDPELFKQAVYKQTMKLFAELEIKRKER 180 K++V+ + ++ K +L+++ GK + E ++ E K+ + A+ E K+K+ Sbjct: 323 KKFVKGSTEKNKLRLQRDQERLGKQLKLRAEREEKEKLKEEAKR------AKEEAKKKKE 376 Query: 181 EAKEMHERKRQREEEIEAQEKAKRER---EWQKNFEESRDGRVDSWRNFQANTKGKKEKK 237 E KE+ E++R+ + E + +EKA+++R E +K +E+ + +++ K KKE++ Sbjct: 377 EEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEE--------KRKKEEE 428 Query: 238 NRTFLRPPKVKMEQRE 253 R ++K E+ E Sbjct: 429 KRLREEEKRIKAEKAE 444 Score = 39.3 bits (90), Expect = 0.003 Identities = 33/139 (23%), Positives = 63/139 (45%), Gaps = 22/139 (15%) Query: 108 KLLLDQEQKKRALDVIQAGKEYVEHTVKERKKQLKKEGKPTIVEEDDPELFKQAVYKQTM 167 KL L ++Q++ GK+ +E K++LK+E K +A + Sbjct: 334 KLRLQRDQER-------LGKQLKLRAEREEKEKLKEEAK-------------RAKEEAKK 373 Query: 168 KLFAELEIKRKE-REAKEMHERKRQREEEIEAQEKAKREREWQKNFEESRDGRVDS-WRN 225 K E E+K KE RE +E E+++ ++ ++ + + +R+ + EE R + R Sbjct: 374 KKEEEKELKEKERREKREKDEKEKAEKQRLKEERRKERQEALEAKLEEKRKKEEEKRLRE 433 Query: 226 FQANTKGKKEKKNRTFLRP 244 + K +K + R F +P Sbjct: 434 EEKRIKAEKAEITRFFQKP 452 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.128 0.344 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,727,459 Number of Sequences: 37866 Number of extensions: 447273 Number of successful extensions: 9644 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 343 Number of HSP's successfully gapped in prelim test: 610 Number of HSP's that attempted gapping in prelim test: 3823 Number of HSP's gapped (non-prelim): 3252 length of query: 253 length of database: 18,247,518 effective HSP length: 100 effective length of query: 153 effective length of database: 14,460,918 effective search space: 2212520454 effective search space used: 2212520454 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.