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Search of human proteins with 111494235
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
(438 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 848 0.0
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 833 0.0
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 770 0.0
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 770 0.0
gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 99 1e-20
gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 99 1e-20
gi|187607364 tuftelin 1 isoform 2 [Homo sapiens] 80 5e-15
gi|9910596 tuftelin 1 isoform 1 [Homo sapiens] 80 5e-15
gi|82880656 coiled-coil domain containing 46 isoform a [Homo sap... 79 6e-15
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 77 4e-14
gi|21735548 centrosomal protein 2 [Homo sapiens] 75 9e-14
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 74 3e-13
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 72 1e-12
gi|156104908 myosin heavy chain 6 [Homo sapiens] 72 1e-12
gi|58530840 desmoplakin isoform I [Homo sapiens] 71 2e-12
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 71 2e-12
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 71 2e-12
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 71 2e-12
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 71 2e-12
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 70 3e-12
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 70 4e-12
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 70 4e-12
gi|121582655 ankyrin repeat domain 35 [Homo sapiens] 70 4e-12
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 70 5e-12
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens] 70 5e-12
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 69 6e-12
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 69 6e-12
gi|237858619 polyamine modulated factor 1 binding protein 1 isof... 69 8e-12
gi|55770834 centromere protein F [Homo sapiens] 69 8e-12
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 69 8e-12
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 848 bits (2190), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN 60
MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN
Sbjct: 1 MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN 60
Query: 61 GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG 120
GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG
Sbjct: 61 GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG 120
Query: 121 DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD 180
DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD
Sbjct: 121 DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD 180
Query: 181 VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE 240
VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE
Sbjct: 181 VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE 240
Query: 241 MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG 300
MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG
Sbjct: 241 MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG 300
Query: 301 ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV
Sbjct: 301 ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
Query: 361 HCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSR 420
HCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSR
Sbjct: 361 HCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSR 420
Query: 421 NYTPYTRVLELTMKKTLT 438
NYTPYTRVLELTMKKTLT
Sbjct: 421 NYTPYTRVLELTMKKTLT 438
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 833 bits (2151), Expect = 0.0
Identities = 438/466 (93%), Positives = 438/466 (93%), Gaps = 28/466 (6%)
Query: 1 MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN 60
MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN
Sbjct: 1 MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN 60
Query: 61 GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG 120
GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG
Sbjct: 61 GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG 120
Query: 121 DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD 180
DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD
Sbjct: 121 DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD 180
Query: 181 VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE 240
VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE
Sbjct: 181 VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE 240
Query: 241 MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG 300
MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG
Sbjct: 241 MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG 300
Query: 301 ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV
Sbjct: 301 ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
Query: 361 HCQQKKVKQMVE----------------------------ENNELQSRLDYLTETQAKTE 392
HCQQKKVKQMVE ENNELQSRLDYLTETQAKTE
Sbjct: 361 HCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTE 420
Query: 393 VETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLELTMKKTLT 438
VETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLELTMKKTLT
Sbjct: 421 VETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLELTMKKTLT 466
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 770 bits (1989), Expect = 0.0
Identities = 406/434 (93%), Positives = 406/434 (93%), Gaps = 28/434 (6%)
Query: 1 MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN 60
MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN
Sbjct: 1 MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN 60
Query: 61 GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG 120
GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG
Sbjct: 61 GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG 120
Query: 121 DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD 180
DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD
Sbjct: 121 DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD 180
Query: 181 VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE 240
VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE
Sbjct: 181 VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE 240
Query: 241 MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG 300
MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG
Sbjct: 241 MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG 300
Query: 301 ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV
Sbjct: 301 ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
Query: 361 HCQQKKVKQMVE----------------------------ENNELQSRLDYLTETQAKTE 392
HCQQKKVKQMVE ENNELQSRLDYLTETQAKTE
Sbjct: 361 HCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTE 420
Query: 393 VETREIGVGCDLLP 406
VETREIGVGCDLLP
Sbjct: 421 VETREIGVGCDLLP 434
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 770 bits (1989), Expect = 0.0
Identities = 406/434 (93%), Positives = 406/434 (93%), Gaps = 28/434 (6%)
Query: 1 MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN 60
MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN
Sbjct: 1 MLRSTSTVTLLSGGAARTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSN 60
Query: 61 GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG 120
GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG
Sbjct: 61 GEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYG 120
Query: 121 DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD 180
DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD
Sbjct: 121 DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVD 180
Query: 181 VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE 240
VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE
Sbjct: 181 VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE 240
Query: 241 MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG 300
MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG
Sbjct: 241 MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG 300
Query: 301 ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV
Sbjct: 301 ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
Query: 361 HCQQKKVKQMVE----------------------------ENNELQSRLDYLTETQAKTE 392
HCQQKKVKQMVE ENNELQSRLDYLTETQAKTE
Sbjct: 361 HCQQKKVKQMVEEIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTE 420
Query: 393 VETREIGVGCDLLP 406
VETREIGVGCDLLP
Sbjct: 421 VETREIGVGCDLLP 434
>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 98.6 bits (244), Expect = 1e-20
Identities = 91/338 (26%), Positives = 161/338 (47%), Gaps = 63/338 (18%)
Query: 89 VYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLEN 148
+Y +++ + EE Y+K +R TL+K+R +M+ D E+R S +H
Sbjct: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKD--EIRHD--------STNHK------- 64
Query: 149 HIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLRE 208
LD + N SDS ++ + + M K++
Sbjct: 65 --------LDAKHCGNLQQGSDS-------------------EMDPSCCSLDLLMKKIKG 97
Query: 209 KQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL- 267
K QL EN++LK+K+++S+EA A +R + ++L+ Y+ + +E ++K K+ L
Sbjct: 98 KDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
Query: 268 ---LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHE 324
LE+ + +E N Q AE LEEK +I EL+ L++RMEKE+ L + L E
Sbjct: 158 VNKLEKEQKLKQHVENLN---QVAE-KLEEKHSQITELENLVQRMEKEKRTLLERKLSLE 213
Query: 325 TEMSGELTDSDK--ERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEE-----NN-- 375
++ +L S + Q L+ + L+E+I HL ++H Q + ++ +++E NN
Sbjct: 214 NKLL-QLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLK 272
Query: 376 ELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTR 413
E R++ L E E + +E+ L S+T RT+
Sbjct: 273 EQDKRIENLREKVNILEAQNKELKTQV-ALSSETPRTK 309
>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 98.6 bits (244), Expect = 1e-20
Identities = 91/338 (26%), Positives = 161/338 (47%), Gaps = 63/338 (18%)
Query: 89 VYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLEN 148
+Y +++ + EE Y+K +R TL+K+R +M+ D E+R S +H
Sbjct: 22 LYESTSAHIIEETEYVKKIRTTLQKIRTQMFKD--EIRHD--------STNHK------- 64
Query: 149 HIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLRE 208
LD + N SDS ++ + + M K++
Sbjct: 65 --------LDAKHCGNLQQGSDS-------------------EMDPSCCSLDLLMKKIKG 97
Query: 209 KQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL- 267
K QL EN++LK+K+++S+EA A +R + ++L+ Y+ + +E ++K K+ L
Sbjct: 98 KDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQRLFENYQTQSEEVRKKQEDSKQLLQ 157
Query: 268 ---LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHE 324
LE+ + +E N Q AE LEEK +I EL+ L++RMEKE+ L + L E
Sbjct: 158 VNKLEKEQKLKQHVENLN---QVAE-KLEEKHSQITELENLVQRMEKEKRTLLERKLSLE 213
Query: 325 TEMSGELTDSDK--ERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEE-----NN-- 375
++ +L S + Q L+ + L+E+I HL ++H Q + ++ +++E NN
Sbjct: 214 NKLL-QLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQHQNLRSVIQEMEGLKNNLK 272
Query: 376 ELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTR 413
E R++ L E E + +E+ L S+T RT+
Sbjct: 273 EQDKRIENLREKVNILEAQNKELKTQV-ALSSETPRTK 309
>gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]
Length = 365
Score = 79.7 bits (195), Expect = 5e-15
Identities = 47/139 (33%), Positives = 77/139 (55%), Gaps = 5/139 (3%)
Query: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 145 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 204
Query: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 205 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 264
Query: 355 HLDDMVHCQQKKVKQMVEE 373
HLDDM+ QQ+KV+QM+E+
Sbjct: 265 HLDDMLKSQQRKVRQMIEQ 283
Score = 52.8 bits (125), Expect = 6e-07
Identities = 67/307 (21%), Positives = 136/307 (44%), Gaps = 47/307 (15%)
Query: 86 EMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEY 145
+ +++ + +QLK E+ YI++ R L+K+R+ + D R L L H Q+
Sbjct: 63 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD------RNLGDSL---HRQE-- 111
Query: 146 LENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDK 205
IQ + F+ +AL S + ++ I + + +L++T + + K
Sbjct: 112 ----IQVVLEKPNGFSQSPTALYSSPPEV----------DTCINEDVESLRKTVQDLLAK 157
Query: 206 LREKQRQLEVAQVENQL-LKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRK---HS 261
L+E +RQ + V ++ L ++++N + RE + Q E ++ E QR+
Sbjct: 158 LQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDR--VEQKEAEVGELQRRLLGME 215
Query: 262 AEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLL 321
E +ALL K++ E++LEE R D ER + + ++ L
Sbjct: 216 TEHQALL--------------AKVREGEVALEE--LRSNNADCQAEREKAATLEKEVAGL 259
Query: 322 EHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRL 381
+ ++ S + + +Q+ E + + I+ D + ++K+ + EN E+ R+
Sbjct: 260 REKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRM 319
Query: 382 DYLTETQ 388
++L E Q
Sbjct: 320 EHLIEKQ 326
>gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]
Length = 390
Score = 79.7 bits (195), Expect = 5e-15
Identities = 47/139 (33%), Positives = 77/139 (55%), Gaps = 5/139 (3%)
Query: 240 EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI 299
E +K KLQE +R+H ++ A + + + E++N +Q E +E+K+ +
Sbjct: 170 ESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDRVEQKEAEV 229
Query: 300 GELDRLIERMEKERHQLQLQLLEHET---EMSGELTD--SDKERYQQLEEASASLRERIR 354
GEL R + ME E L ++ E E E+ D +++E+ LE+ A LRE+I
Sbjct: 230 GELQRRLLGMETEHQALLAKVREGEVALEELRSNNADCQAEREKAATLEKEVAGLREKIH 289
Query: 355 HLDDMVHCQQKKVKQMVEE 373
HLDDM+ QQ+KV+QM+E+
Sbjct: 290 HLDDMLKSQQRKVRQMIEQ 308
Score = 52.8 bits (125), Expect = 6e-07
Identities = 67/307 (21%), Positives = 136/307 (44%), Gaps = 47/307 (15%)
Query: 86 EMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEY 145
+ +++ + +QLK E+ YI++ R L+K+R+ + D R L L H Q+
Sbjct: 88 DKMIHEKNINQLKSEVQYIQEARNCLQKLREDISSKLD------RNLGDSL---HRQE-- 136
Query: 146 LENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDK 205
IQ + F+ +AL S + ++ I + + +L++T + + K
Sbjct: 137 ----IQVVLEKPNGFSQSPTALYSSPPEV----------DTCINEDVESLRKTVQDLLAK 182
Query: 206 LREKQRQLEVAQVENQL-LKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRK---HS 261
L+E +RQ + V ++ L ++++N + RE + Q E ++ E QR+
Sbjct: 183 LQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREEDR--VEQKEAEVGELQRRLLGME 240
Query: 262 AEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLL 321
E +ALL K++ E++LEE R D ER + + ++ L
Sbjct: 241 TEHQALL--------------AKVREGEVALEE--LRSNNADCQAEREKAATLEKEVAGL 284
Query: 322 EHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRL 381
+ ++ S + + +Q+ E + + I+ D + ++K+ + EN E+ R+
Sbjct: 285 REKIHHLDDMLKSQQRKVRQMIEQLQNSKAVIQSKDATIQELKEKIAYLEAENLEMHDRM 344
Query: 382 DYLTETQ 388
++L E Q
Sbjct: 345 EHLIEKQ 351
>gi|82880656 coiled-coil domain containing 46 isoform a [Homo
sapiens]
Length = 955
Score = 79.3 bits (194), Expect = 6e-15
Identities = 87/368 (23%), Positives = 159/368 (43%), Gaps = 40/368 (10%)
Query: 43 EQCEKKIERKEQLLDLSNGEPTR---------KLPQGVVYGVVRRSDQNQQKEMVVYGWS 93
E +KKI + E+ L + TR + + R+ + N +K VY
Sbjct: 565 EDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEK---VYAEM 621
Query: 94 TSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQ 153
Q+++ + ++ EK K +++RQ+ Q EL + H Q++
Sbjct: 622 KEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEK--------- 672
Query: 154 SSALDRFNAMNSALASDSI----GLQKTLVDVTLENSN----IKDQIRNLQQTYEASMDK 205
+ L + NA +L D L+K L +E+ N K + + EA + K
Sbjct: 673 THLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHK 732
Query: 206 LREKQRQLEVAQVENQLLKM---KVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSA 262
LRE+ + +Q + QL+++ + E Q A E + KL ++ E+ E ++ H+A
Sbjct: 733 LREELINVN-SQRKQQLVELGLLREEEKQRATRE-HEIVVNKLKAESEKMKIELKKTHAA 790
Query: 263 EKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLE 322
E E LE+ NS LK IE+ + L + Q I EL I +++E Q QL
Sbjct: 791 ETEMTLEKANSKLKQIEKEYTQ------KLAKSSQIIAELQTTISSLKEENSQQQLAAER 844
Query: 323 HETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLD 382
++ + D K+ + ++A L++ + + + V C +KK++ E+ E + +
Sbjct: 845 RLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIR 904
Query: 383 YLTETQAK 390
ET+ K
Sbjct: 905 QEYETKLK 912
Score = 46.6 bits (109), Expect = 4e-05
Identities = 36/177 (20%), Positives = 80/177 (45%), Gaps = 23/177 (12%)
Query: 242 TKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFL---------------KAIEEANKKMQ 286
TK + +++ E+ + Q+KH A+ + +LE N+ + + I + KK+Q
Sbjct: 261 TKMMEAKFHEEKLKLQQKHDADVQKILERKNNEIEELKTLYRSKQHETEETIRKLEKKVQ 320
Query: 287 A----AEISLEEKDQRIGELDRLIER-MEKERHQLQLQLLEHETEMSGELTDSDKERYQQ 341
++ E K+ +I EL ++ E+ E + + +L EM E D K+ +
Sbjct: 321 TLIRDCQVIRETKEDQIAELKKICEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTEN 380
Query: 342 LEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREI 398
++E R+ ++ Q + M++ EL++R+ LT + ++ +++
Sbjct: 381 IQELLEDTNVRLNKMESEYMAQTQSTNHMIK---ELEARVQQLTGEAENSNLQRQKL 434
Score = 46.6 bits (109), Expect = 4e-05
Identities = 57/241 (23%), Positives = 113/241 (46%), Gaps = 17/241 (7%)
Query: 174 LQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREK-QRQLEVAQV-----ENQLLKMKV 227
+QK L E +K R+ Q E ++ KL +K Q + QV E+Q+ ++K
Sbjct: 283 VQKILERKNNEIEELKTLYRSKQHETEETIRKLEKKVQTLIRDCQVIRETKEDQIAELK- 341
Query: 228 ESSQEANAEVMREMTKKLYSQYEEKLQEE---QRKHSAEKEALLEETNSFLKAIE-EANK 283
+ +++ + + KKL++ E QE+ Q++H+ + LLE+TN L +E E
Sbjct: 342 KICEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMA 401
Query: 284 KMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLE 343
+ Q+ ++E + R+ +L E +R +L + + E E ++T S+ Q+++
Sbjct: 402 QTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQE--KAELERCYQITCSE---LQEVK 456
Query: 344 EASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCD 403
+L + HL + K ++ + + L + L+ ++A + +E E V C
Sbjct: 457 ARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEHALSASKASSMIEELEQNV-CQ 515
Query: 404 L 404
L
Sbjct: 516 L 516
Score = 46.2 bits (108), Expect = 6e-05
Identities = 71/368 (19%), Positives = 157/368 (42%), Gaps = 62/368 (16%)
Query: 100 EMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDR 159
E+ +K R TL K + + DY E K+ Q + ++ +QE+
Sbjct: 451 ELQEVKARRNTLHKEKDHLVNDY-EQNMKLLQTKYDADINLLKQEH-------------- 495
Query: 160 FNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVE 219
A++++ AS I LE N+ + LQ++ +LR+++ + ++ +
Sbjct: 496 --ALSASKASSMIE--------ELEQ-NVCQLKQQLQESELQRKQQLRDQENKFQMEKSH 544
Query: 220 NQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEE----------QRKHSAEKEALLE 269
+ + K ++ + +E T+K ++EE L+E+ QR + + +A LE
Sbjct: 545 LKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALE 604
Query: 270 ETNSFL-----KAIEEANKKMQAAEI------SLEEKDQR--IGELDRLIERMEKERHQL 316
E + K E ++M+ E SL EK + + +L+ + +R E++ +L
Sbjct: 605 EFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVEL 664
Query: 317 QLQLLEHETEMSGELTDSDKER-------YQQLEEASASLR-ERIRHLDDMVHCQQKKVK 368
+ LEHE E + L + E+ +++E LR + H + + +++ +
Sbjct: 665 K---LEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQ 721
Query: 369 QMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRV 428
+ + ++ + L ++ + + E+G+ + + R EIV+ +
Sbjct: 722 VIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVV--NKLKAESEK 779
Query: 429 LELTMKKT 436
+++ +KKT
Sbjct: 780 MKIELKKT 787
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 76.6 bits (187), Expect = 4e-14
Identities = 74/342 (21%), Positives = 159/342 (46%), Gaps = 21/342 (6%)
Query: 76 VRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQE 135
+RR + Q + + + ++L+ + Y + LE + + + + +L Q
Sbjct: 109 LRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQA 168
Query: 136 LSVSHAQQEYLENHIQTQSSALD-------RFNAMNSALASDSIGLQKTLVDVTLENSNI 188
LS Q++ + +I+ + D R + L + LQ+ L V E S I
Sbjct: 169 LSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEI 228
Query: 189 KDQIRNLQQTYEASMDKLREKQRQLEVAQV--ENQLLKMKVESSQEANA---EVMREMTK 243
+ ++ L++ E + L ++Q Q E + E Q + K+++ E N + ++ +
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEE 288
Query: 244 KLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIE---EANKKMQAAEISLEEKDQRIG 300
K++ Q EEK+QE + K ++E + E+ + E E +KM+ E + EK+++I
Sbjct: 289 KMWRQ-EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347
Query: 301 ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
EL+ + EK R Q + + E + + + + + ++Q EE E+IR ++M+
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ-EEKIREQEEKIREQEEMM 406
Query: 361 HCQQKKV----KQMVEENNELQSRLDYLTETQAKTEVETREI 398
Q++K+ ++M E+ E+Q + + + + K + ++I
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448
Score = 68.6 bits (166), Expect = 1e-11
Identities = 68/341 (19%), Positives = 158/341 (46%), Gaps = 29/341 (8%)
Query: 95 SQLKEEMNYIKDVRATLEKVRKRMYGDY---DEMRQKIRQLTQELSVSHAQQEYLENHIQ 151
+Q K+ YI+++ + + +Y + +E+++K +L ++L + +++ ++ +++
Sbjct: 174 TQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVK 233
Query: 152 TQSSALDRFNAM----NSALASDSIGLQKTLVDVTLENSNIKDQIRN-LQQTYEASMDKL 206
L+R + +D +G + V L+ ++++ N L Q E M +
Sbjct: 234 ELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQ 293
Query: 207 REKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYE------EKLQE-EQRK 259
EK ++ E E + + E E+M E +K+ Q E EK++E E++
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 260 HSAEKEALLEETNSFLKAIEEANK------KMQAAEISLEEKDQRIGELDRLIERMEKER 313
H EK EE + I E K KM E + E++++I E + +++ E++
Sbjct: 354 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKM 413
Query: 314 HQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEE 373
+ + ++ E E EM + +E+ ++ EE ++IR ++ + Q++ +++ E+
Sbjct: 414 GEQEEKMWEQEEEMQEQ-----EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468
Query: 374 NNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTRE 414
E + ++ E +AK + + ++ + + Q + RE
Sbjct: 469 MGEQEGKM---CEQEAKMQEQEEKMRRQEEKIREQEKKIRE 506
Score = 60.5 bits (145), Expect = 3e-09
Identities = 63/298 (21%), Positives = 131/298 (43%), Gaps = 33/298 (11%)
Query: 77 RRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQEL 136
R +Q+E + + +EEM + K+ EK+R++ + E +KIR+L +++
Sbjct: 300 REEKIQEQEEKIREQEEKMRRQEEMMWEKE-----EKMRRQEEMMW-EKEEKIRELEEKM 353
Query: 137 SVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQ 196
H Q++ E + Q R Q+ + + I++Q ++
Sbjct: 354 ---HEQEKIREQEEKRQEEEKIREQEKR----------QEQEAKMWRQEEKIREQEEKIR 400
Query: 197 QTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYE-----E 251
+ E M + EK + E E + + E E +RE KK+ Q E E
Sbjct: 401 EQ-EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459
Query: 252 KLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEK 311
++ +EQ + E+E + E + ++E +KM+ E + E++++I E + I E+
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEA---KMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 516
Query: 312 ERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQ 369
+ + ++ E E +M +E+ Q+ EE E++R + + Q++K+++
Sbjct: 517 MMQEQEEKMWEQEEKMC-----EQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 47.0 bits (110), Expect = 3e-05
Identities = 58/309 (18%), Positives = 125/309 (40%), Gaps = 36/309 (11%)
Query: 32 RLTVPPESPVPEQCEKKIERKEQLLDLSNG--EPTRKLPQGVVYGVVRRSDQNQQKEMVV 89
RL E + Q EK ER+E++ + E K+ + + +Q+EM+
Sbjct: 281 RLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM- 339
Query: 90 YGWSTSQ----LKEEMNYIKDVRATLEKVRKRMYGDYDEMRQ-----------KIRQLTQ 134
W + L+E+M+ + +R EK ++ E RQ KIR+ +
Sbjct: 340 --WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397
Query: 135 ELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRN 194
++ Q+E ++ + ++ + +++ + + I++Q
Sbjct: 398 KI---REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEK 454
Query: 195 LQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQ 254
+++ E M + EK + E E + + E E +RE KK+ Q EEK++
Sbjct: 455 IREQ-EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQ-EEKIR 512
Query: 255 EEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERH 314
E++ ++E + E+ +KM E ++E+++++ + + E
Sbjct: 513 EQEEMMQEQEEKMWEQ-----------EEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLR 561
Query: 315 QLQLQLLEH 323
Q + ++ EH
Sbjct: 562 QQEEKMQEH 570
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 75.5 bits (184), Expect = 9e-14
Identities = 69/313 (22%), Positives = 145/313 (46%), Gaps = 15/313 (4%)
Query: 95 SQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQS 154
+ L+ ++ ++ A L+ + + + +E+++K+ + + + Q E L + Q
Sbjct: 662 THLEAQLQKAEEAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQE 721
Query: 155 SALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLE 214
L R AL + L+ L V + ++ +Q++ L E L E Q+Q
Sbjct: 722 EVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQQNS 781
Query: 215 VAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALL--EETN 272
V +V L++++++ +A + E+ E+ Q EQ + +A ++ +E
Sbjct: 782 VIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQEGK 841
Query: 273 SFLKAIEEANKKM--QAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGE 330
+ L+ + A++K Q E +E+ EL + +E +E+E+ +L+++L E +TEM
Sbjct: 842 TALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKMELEMRLKEQQTEMEAI 901
Query: 331 LTDSDKERYQQLEEASASL-----RERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLT 385
++ER Q E A + +ER+ L+ ++ Q K++ + + +L+ RL
Sbjct: 902 QAQREEER-TQAESALCQMQLETEKERVSLLETLLQTQ----KELADASQQLE-RLRQDM 955
Query: 386 ETQAKTEVETREI 398
+ Q E ET I
Sbjct: 956 KVQKLKEQETTGI 968
Score = 67.8 bits (164), Expect = 2e-11
Identities = 64/301 (21%), Positives = 141/301 (46%), Gaps = 21/301 (6%)
Query: 110 TLEKVRKRMYGDYDEMRQKIRQLTQELS---VSHAQQEYLENHIQTQ----SSALDRFNA 162
TL + + + + + +RQ+ ++T L+ S A+ EN ++T+ +A + +A
Sbjct: 544 TLREALESSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVKLSA 603
Query: 163 MNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQL 222
+N ALA D +GL + L+ + EN ++ ++ +Q A L E +++ E +N
Sbjct: 604 LNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTH 663
Query: 223 LKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEAN 282
L+ +++ ++EA AE+ ++ +E+ +E Q+K S + T + +EA
Sbjct: 664 LEAQLQKAEEAGAELQADL-----RDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAK 718
Query: 283 KKMQAAEISLEEKDQRIGE---LDRLIERMEKERHQL--QLQLLEHETEMSGELTDSDKE 337
++ + +++EK+ + E L+ ++ +E++R L QLQ L E+ ++
Sbjct: 719 RQEEVLARAVQEKEALVREKAALEVRLQAVERDRQDLAEQLQGLSSAKELLESSLFEAQQ 778
Query: 338 RYQQLEEASASLRERIRHLDDMVHCQQKKVK----QMVEENNELQSRLDYLTETQAKTEV 393
+ +E L +I+ + Q +V+ ++ E ++ + D A+ E
Sbjct: 779 QNSVIEVTKGQLEVQIQTVTQAKEVIQGEVRCLKLELDTERSQAEQERDAAARQLAQAEQ 838
Query: 394 E 394
E
Sbjct: 839 E 839
Score = 62.8 bits (151), Expect = 6e-10
Identities = 77/335 (22%), Positives = 144/335 (42%), Gaps = 53/335 (15%)
Query: 43 EQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMN 102
++ ++ E KEQ L E R L Q + + QQ++ G ++KE+ +
Sbjct: 1788 QEAREQGELKEQSLQSQLDEAQRALAQRD-----QELEALQQEQQQAQG-QEERVKEKAD 1841
Query: 103 YIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNA 162
++ K +G+ + +++ R+L +EL+V + + LE L A
Sbjct: 1842 ALQGALEQAHMTLKERHGELQDHKEQARRLEEELAVEGRRVQALEE-------VLGDLRA 1894
Query: 163 MNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQL 222
+ + LQ+ + E+ + + R LQ ++ + L+E+ ++LE + E+Q
Sbjct: 1895 ESREQEKALLALQQQCAEQAQEH---EVETRALQDSWLQAQAVLKERDQELEALRAESQS 1951
Query: 223 LKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEAN 282
+ + E+++ A AE ++E K ++ + K E+ AE LE + + L+A +A
Sbjct: 1952 SRHQEEAAR-ARAEALQEALGKAHAALQGK--EQHLLEQAELSRSLEASTATLQASLDA- 2007
Query: 283 KKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSD---KERY 339
QA LEE L++Q GE+ D D +E
Sbjct: 2008 --CQAHSRQLEEA--------------------LRIQ--------EGEIQDQDLRYQEDV 2037
Query: 340 QQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEN 374
QQL++A A E +RH + +K + Q V+EN
Sbjct: 2038 QQLQQALAQRDEELRHQQEREQLLEKSLAQRVQEN 2072
Score = 58.2 bits (139), Expect = 1e-08
Identities = 71/342 (20%), Positives = 147/342 (42%), Gaps = 35/342 (10%)
Query: 65 RKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDE 124
R+L Q G Q E V KE + +++ LE + + E
Sbjct: 831 RQLAQAEQEGKTALEQQKAAHEKEVNQLREKWEKERSWHQQELAKALESLEREKM----E 886
Query: 125 MRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLE 184
+ ++++ E+ AQ+E E Q +S+ M + + L +TL+ E
Sbjct: 887 LEMRLKEQQTEMEAIQAQRE--EERTQAESALCQ----MQLETEKERVSLLETLLQTQKE 940
Query: 185 NSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKK 244
++ Q+ L+Q + + KL+E++ +L+ +++ +Q E R+
Sbjct: 941 LADASQQLERLRQ--DMKVQKLKEQET--------TGILQTQLQEAQRELKEAARQHRDD 990
Query: 245 LYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDR 304
L + EE Q K +K+ +E+ S L A +++ + + E ++EK + E +R
Sbjct: 991 LAALQEESSSLLQDKMDLQKQ--VEDLKSQLVAQDDSQRLV---EQEVQEKLRETQEYNR 1045
Query: 305 LIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQL-------EEASASLRERIRHLD 357
+ + +E+E+ L L L+E E + L ++D R Q+L +EA +E ++
Sbjct: 1046 IQKELEREKASLTLSLMEKEQRLL-VLQEADSIRQQELSALRQDMQEAQGEQKELSAQME 1104
Query: 358 DMVHCQQKKVKQMVEENNELQSRLD--YLTETQAKTEVETRE 397
+ ++K + + +L L+ ++TE Q + + +E
Sbjct: 1105 LLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQE 1146
Score = 51.2 bits (121), Expect = 2e-06
Identities = 67/320 (20%), Positives = 151/320 (47%), Gaps = 36/320 (11%)
Query: 96 QLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSS 155
+L+E +K R +E+++++ + + Q + + QEL + + + LE+ Q+
Sbjct: 1624 ELQERDQEVKSQREQIEELQRQK----EHLTQDLERRDQELMLQKERIQVLEDQRTRQTK 1679
Query: 156 ALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKL-------RE 208
L+ L + L++ ++T + ++++ + +A L R+
Sbjct: 1680 ILEE------DLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRD 1733
Query: 209 KQRQLEVAQV---ENQLLKMKVESSQEANAEVMREMTKKLYSQYE-------EKLQEEQR 258
K++++E Q E Q LK ++E + + E T L SQ E ++LQE +
Sbjct: 1734 KEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGE-TSLLLSQREQEIVVLQQQLQEARE 1792
Query: 259 KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQL 318
+ ++++L + + +A+ + +++++A + +E+ Q G+ +R+ E+ + + L+
Sbjct: 1793 QGELKEQSLQSQLDEAQRALAQRDQELEALQ---QEQQQAQGQEERVKEKADALQGALE- 1848
Query: 319 QLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQ 378
Q E GEL D KE+ ++LEE A R++ L++++ + + + E+ L
Sbjct: 1849 QAHMTLKERHGELQD-HKEQARRLEEELAVEGRRVQALEEVLGDLRAESR---EQEKALL 1904
Query: 379 SRLDYLTETQAKTEVETREI 398
+ E + EVETR +
Sbjct: 1905 ALQQQCAEQAQEHEVETRAL 1924
Score = 49.3 bits (116), Expect = 7e-06
Identities = 65/321 (20%), Positives = 141/321 (43%), Gaps = 49/321 (15%)
Query: 84 QKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQ 143
Q+ + + + ++ +EE+ ++ LEK R+ + + +++ QE+ + Q
Sbjct: 1420 QENLALLTQTLAEREEEVETLRGQIQELEKQREMQKAALELLSLDLKKRNQEVDLQQEQI 1479
Query: 144 EYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASM 203
+ LE S L + +Q+ +T++ ++QIR L
Sbjct: 1480 QELEK--------------CRSVLEHLPMAVQEREQKLTVQ----REQIREL-------- 1513
Query: 204 DKLREKQRQLEVAQVENQLLKM-KVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSA 262
+K RE QR + +E+QLL++ K + E+ ++++ K+L + L+ E+ H
Sbjct: 1514 EKDRETQRNV----LEHQLLELEKKDQMIESQRGQVQDLKKQLVTLECLALELEENHHKM 1569
Query: 263 EKEALLEETNSFLKAIEEANKKMQAA----EISLEEKDQRIGELDRLIERMEKERHQLQL 318
E + L +K +E + + A + LEE+ Q + I +E L
Sbjct: 1570 ECQQKL------IKELEGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLAR 1623
Query: 319 QLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQ 378
+L E + E+ S +E+ ++L+ L + + D + Q++++ Q++E+ Q
Sbjct: 1624 ELQERDQEVK-----SQREQIEELQRQKEHLTQDLERRDQELMLQKERI-QVLEDQRTRQ 1677
Query: 379 SRLDYLTETQAKTEVETREIG 399
+++ L E + ++ RE G
Sbjct: 1678 TKI--LEEDLEQIKLSLRERG 1696
Score = 48.1 bits (113), Expect = 2e-05
Identities = 72/375 (19%), Positives = 155/375 (41%), Gaps = 33/375 (8%)
Query: 41 VPEQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEE 100
V E+ +K ++EQ+ +L T++ + + DQ + + LK++
Sbjct: 1496 VQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIESQR----GQVQDLKKQ 1551
Query: 101 MNYIKDVRATLEKVRKRMYGDYDEMRQK-IRQLTQELSVSHAQQEYLENHIQTQSSALDR 159
+ ++ + LE+ +M E +QK I++L + +L ++ +S L
Sbjct: 1552 LVTLECLALELEENHHKM-----ECQQKLIKELEGQRETQRVALTHLTLDLEERSQELQA 1606
Query: 160 FNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVE 219
++ L S S L + L + E + ++QI LQ+ E L + ++L + +
Sbjct: 1607 QSSQIHDLESHSTVLARELQERDQEVKSQREQIEELQRQKEHLTQDLERRDQELMLQKER 1666
Query: 220 NQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIE 279
Q+L E + +++ E + Q + L+E R+ + +++ + E E
Sbjct: 1667 IQVL----EDQRTRQTKILEEDLE----QIKLSLRERGRELTTQRQLMQERA-------E 1711
Query: 280 EANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERY 339
E +A SLE + + ++ +E ++ H+LQ E+ +L + +
Sbjct: 1712 EGKGPSKAQRGSLEHMKLILRDKEKEVECQQEHIHELQ--------ELKDQLEQQLQGLH 1763
Query: 340 QQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIG 399
+++ E S L +R + + + Q+ +Q + LQS+LD A+ + E +
Sbjct: 1764 RKVGETSLLLSQREQEIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQ 1823
Query: 400 VGCDLLPSQTGRTRE 414
Q R +E
Sbjct: 1824 QEQQQAQGQEERVKE 1838
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/327 (20%), Positives = 141/327 (43%), Gaps = 35/327 (10%)
Query: 93 STSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQT 152
ST+ L+ ++ + LE+ + G+ + + ++ Q+L + AQ++ H Q
Sbjct: 1997 STATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQQE 2056
Query: 153 QSSALDRFNAM----NSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTY---EASMDK 205
+ L++ A N ++G ++ ++ + +R LQ T E + +
Sbjct: 2057 REQLLEKSLAQRVQENMIQEKQNLGQEREEEEIR----GLHQSVRELQLTLAQKEQEILE 2112
Query: 206 LREKQRQ--LEVAQVENQLLKMKVESSQEANAE--VMREMTKKLYSQYEEKLQEEQRKHS 261
LRE Q++ LE ++ M+ +S + + E + RE+ + + + + +E + +
Sbjct: 2113 LRETQQRNNLEALPHSHKTSPMEEQSLKLDSLEPRLQRELERLQAALRQTEAREIEWREK 2172
Query: 262 AEKEAL-LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQL 320
A+ AL L +T + + +++E +QA+ + +R E RL + +E R L+ +
Sbjct: 2173 AQDLALSLAQTKASVSSLQEVAMFLQASVL------ERDSEQQRLQDELELTRRALEKER 2226
Query: 321 LEHETEMSGELTDSDKERYQQLEEASA-------------SLRERIRHLDDMVHCQQKKV 367
L S S E+ QL E S S R+R+ HL V +
Sbjct: 2227 LHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSPDGMEKQSWRQRLEHLQQAVARLEIDR 2286
Query: 368 KQMVEENNELQSRLDYLTETQAKTEVE 394
++ N +L+S L+ + + K + E
Sbjct: 2287 SRLQRHNVQLRSTLEQVERERRKLKRE 2313
Score = 45.1 bits (105), Expect = 1e-04
Identities = 63/310 (20%), Positives = 132/310 (42%), Gaps = 33/310 (10%)
Query: 107 VRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSA 166
VR+ L + R+ + ++RQ++ + +++ Q + E + L +
Sbjct: 391 VRSVLTRRRQAV----QDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTGERDT 446
Query: 167 LASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMK 226
LA ++ LQ + ++ E ++ L+Q E L ++ +L VE L+++
Sbjct: 447 LAGQTVDLQGEVDSLSKERELLQKAREELRQQLEV----LEQEAWRLRRVNVE---LQLQ 499
Query: 227 VESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANK--- 283
+S+Q E E+ L + E+LQE A++ L E + +A+E ++
Sbjct: 500 GDSAQGQKEEQQEEL--HLAVRERERLQEMLMGLEAKQSESLSELITLREALESSHLEGE 557
Query: 284 --KMQAAEIS--LEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDK--- 336
+ + E++ L +Q I EL ++ E L+ ++ E DK
Sbjct: 558 LLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLRAAAVK--LSALNEALALDKVGL 615
Query: 337 -ERYQQLEEASASLRERIRHLDDMVHCQQ-------KKVKQMVEENNELQSRLDYLTETQ 388
++ QLEE + S+ R+ + + Q K+ + + E+N L+++L E
Sbjct: 616 NQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKNTHLEAQLQKAEEAG 675
Query: 389 AKTEVETREI 398
A+ + + R+I
Sbjct: 676 AELQADLRDI 685
Score = 40.8 bits (94), Expect = 0.002
Identities = 80/411 (19%), Positives = 163/411 (39%), Gaps = 75/411 (18%)
Query: 46 EKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIK 105
+K++ER++ L LS E ++L V++ +D +Q+E+ ++E K
Sbjct: 1047 QKELEREKASLTLSLMEKEQRLL------VLQEADSIRQQELSAL---RQDMQEAQGEQK 1097
Query: 106 DVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNS 165
++ A +E +R+ + + + QL +EL SH ++ L + Q + + +
Sbjct: 1098 ELSAQMELLRQEVKEKEADFLAQEAQLLEELEASHITEQQLRASLWAQEAKAAQ---LQL 1154
Query: 166 ALASDSIGLQKTLVDVTLEN-SNIKDQIRNLQQTYEASMDKLREKQRQLE--------VA 216
L S L+ + N + + Q+ +L + ++ + E + +L V
Sbjct: 1155 RLRSTESQLEALAAEQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSVW 1214
Query: 217 QVE------NQLLK---MKVESSQEANAEVMREMTKKLYSQYE---------EKLQEEQR 258
+E L K + S EA A + ++ + L+ + +KL+E
Sbjct: 1215 GLEPDQNGARSLFKRGPLLTALSAEAVASALHKLHQDLWKTQQTRDVLRDQVQKLEERLT 1274
Query: 259 KHSAEKEAL---LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQ 315
AEK + L++ L +E K + + SLE + + EL + ++ +
Sbjct: 1275 DTEAEKSQVHTELQDLQRQLSQNQEEKSKWEGKQNSLESE---LMELHETMASLQSRLRR 1331
Query: 316 LQLQLLEHETEMSGELTDSDKERYQQ---------------------LEEASASLRERIR 354
+LQ +E + E EL + KE LEE + R ++
Sbjct: 1332 AELQRMEAQGER--ELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEEDLRTARSALK 1389
Query: 355 HLDDMVHCQQKKVKQM-------VEENNELQSRLDYLTETQAKTEVETREI 398
++ V ++++ + + V + LQ L LT+T A+ E E +
Sbjct: 1390 LKNEEVESERERAQALQEQGELKVAQGKALQENLALLTQTLAEREEEVETL 1440
Score = 40.8 bits (94), Expect = 0.002
Identities = 56/298 (18%), Positives = 124/298 (41%), Gaps = 33/298 (11%)
Query: 74 GVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEK-VRKRMYGDYDEMRQKIRQL 132
G ++ D Q+++ + +Q EE+ + ++ LEK + +R+ + + +Q + Q
Sbjct: 2024 GEIQDQDLRYQEDVQQLQQALAQRDEELRHQQEREQLLEKSLAQRVQENMIQEKQNLGQE 2083
Query: 133 TQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQI 192
+E + Q E + + + ++ L + +E ++K +
Sbjct: 2084 REEEEIRGLHQSVRELQLTLAQKEQEILELRETQQRNNLEALPHSHKTSPMEEQSLK--L 2141
Query: 193 RNLQQTYEASMDKLREKQRQLEVAQVE----NQLLKMKVESSQEANAEVMREMTKKLYSQ 248
+L+ + +++L+ RQ E ++E Q L + + ++ A+ ++E+ L +
Sbjct: 2142 DSLEPRLQRELERLQAALRQTEAREIEWREKAQDLALSLAQTK-ASVSSLQEVAMFLQAS 2200
Query: 249 YEEKLQEEQR--------KHSAEKEALLEE-TNSFLKAIEEANKKMQAAEISLEEKD--- 296
E+ E+QR + + EKE L S + + +Q E+S E +
Sbjct: 2201 VLERDSEQQRLQDELELTRRALEKERLHSPGATSTAELGSRGEQGVQLGEVSGVEAEPSP 2260
Query: 297 ---------QRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEA 345
QR+ L + + R+E +R +LQ H ++ L ++ER + EA
Sbjct: 2261 DGMEKQSWRQRLEHLQQAVARLEIDRSRLQ----RHNVQLRSTLEQVERERRKLKREA 2314
Score = 33.5 bits (75), Expect = 0.39
Identities = 42/233 (18%), Positives = 95/233 (40%), Gaps = 16/233 (6%)
Query: 183 LENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMT 242
LE + ++D++ L L + Q+Q E + + L+ VE + + E+M
Sbjct: 276 LEKAELQDRVTELSAL-------LTQSQKQNEDYEKMIKALRETVEILETNHTELMEHEA 328
Query: 243 KKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGEL 302
+ EEKL +Q + ++EE ++ + N ++ + D + +
Sbjct: 329 SLSRNAQEEKLSLQQVIKDI-TQVMVEEGDNIAQGSGHEN-SLELDSSIFSQFDYQDADK 386
Query: 303 DRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHC 362
+ R R + +Q L + E + ++++ Q EE +LR+R++ L
Sbjct: 387 ALTLVRSVLTRRRQAVQDLRQQLAGCQEAVNLLQQQHDQWEEEGKALRQRLQKLTG---- 442
Query: 363 QQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTREI 415
+ + + +LQ +D L++ + + E+ ++L + R R +
Sbjct: 443 ---ERDTLAGQTVDLQGEVDSLSKERELLQKAREELRQQLEVLEQEAWRLRRV 492
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 73.9 bits (180), Expect = 3e-13
Identities = 89/410 (21%), Positives = 184/410 (44%), Gaps = 57/410 (13%)
Query: 50 ERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRA 109
E ++ L E R+ + + ++ ++ ++E + S++K+E+ + ++
Sbjct: 415 ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMK-KS 473
Query: 110 TLEKVRKRMYGDYDEMRQKIRQLTQEL-------------SVSHAQQEYL---ENHIQTQ 153
+ E++ K E+ +K ++LT++L ++ +Q EYL + Q +
Sbjct: 474 SEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQE 533
Query: 154 SSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQL 213
S AL+ A+ ++S + L D+ E + +I L+ + E S+ + + + + L
Sbjct: 534 SLALEELELQKKAILTES---ENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDL 590
Query: 214 EV--------------AQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRK 259
V VE K ++ES + + E + L QY+ ++++ + K
Sbjct: 591 AVHLEAEKNKHNKEITVMVEKH--KTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREK 648
Query: 260 HSAEKEALLEETNSFLKA-IEEANKKMQAAEISLEEKDQRIGELDRL---IERMEKERHQ 315
EKE LL++ +A IEE N+K +LE+ D + EL+ L + + K RH+
Sbjct: 649 CEQEKETLLKDKEIIFQAHIEEMNEK------TLEKLDVKQTELESLSSELSEVLKARHK 702
Query: 316 L--QLQLLEHETE-MSGEL---TDSDKERYQQ-----LEEASASLRERIRHLDDMVHCQQ 364
L +L +L+ +T+ M EL D K +QQ ++E S++ + L D ++ +
Sbjct: 703 LEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLE 762
Query: 365 KKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTRE 414
+K+ + E Q+ ++ L ++E E ++ D+ S T E
Sbjct: 763 LLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHE 812
Score = 67.4 bits (163), Expect = 2e-11
Identities = 84/439 (19%), Positives = 194/439 (44%), Gaps = 69/439 (15%)
Query: 46 EKKIERKEQLLDLSNGEPTRKLPQGVVYGV-------VRRSDQNQQKEMVVYGWSTSQLK 98
EK++ RKEQ L R+ + + + ++ S + +Q+E + Q K
Sbjct: 486 EKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK 545
Query: 99 ----EEMNYIKDVRATLEKVRKRMY---GDYDEMRQKIRQLTQELSVSHAQQEYLENH-- 149
E N ++D++ E R R+ ++ Q+ + +++L+V ++ N
Sbjct: 546 AILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEI 605
Query: 150 ---IQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQ------IRNLQQTYE 200
++ + L+ AL ++ + + K +E K + +++ + ++
Sbjct: 606 TVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQ 665
Query: 201 ASMDKLREKQ-RQLEVAQVENQLLK------MKVESSQEANAEVMREMTKKLYSQYEEKL 253
A ++++ EK +L+V Q E + L +K E V+++ T K+ + E K+
Sbjct: 666 AHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKM 725
Query: 254 QEEQRKHSAEKEALLEETNSFLKAIEEANK-KMQAAEISLEEKDQRIGELDRLIERMEKE 312
E++ H + +++++E ++ E+A K ++ E+ L+E+D+ + E +E +E +
Sbjct: 726 DEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEAD 785
Query: 313 --RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDM----------V 360
R + +LQ + ++ + E+ + EE A L++++ L+ V
Sbjct: 786 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV 845
Query: 361 HCQQKKV---------------KQMVEENNELQSRLDYLT-------ETQAKTEVETREI 398
Q+K V +Q+ ++N+E++ ++ LT E K + +T++I
Sbjct: 846 EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 905
Query: 399 GVGCD--LLPSQTGRTREI 415
V + +L + G+ +EI
Sbjct: 906 LVEKENMILQMREGQKKEI 924
Score = 65.5 bits (158), Expect = 9e-11
Identities = 77/397 (19%), Positives = 171/397 (43%), Gaps = 75/397 (18%)
Query: 76 VRRSDQNQQKEMVVYGWSTSQLKEEM----------------NYIKDVRATLEKVRKRMY 119
V ++ ++E+ V T ++K+E+ + IK+ ++++ K +
Sbjct: 696 VLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALK 755
Query: 120 GDYDEMRQKIRQLTQELSVSHAQQEYLE-------NHIQTQSSALDRFNAMNSALASDSI 172
+++ +++ + L A E LE +Q S+ LD F + SA +
Sbjct: 756 DQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK 815
Query: 173 GLQKTLVDVTLENSNIK-DQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQ 231
++ L + + +++ ++I +Q E K ++ +L+ +++ Q L ++E
Sbjct: 816 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQK-KDVCTELDAHKIQVQDLMQQLEKQ- 873
Query: 232 EANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFL-------KAIEEANKK 284
N+E M + K L YE KL++ ++ K+ L+E+ N L K IE +K
Sbjct: 874 --NSE-MEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQK 930
Query: 285 MQAAEISL----EEKDQRIGELDRLIERMEKERHQLQ----LQLLEHETEMSGELTDSDK 336
+ A E S+ EE + + ++ +E+++++ ++Q +LL+ E ++ EL ++
Sbjct: 931 LSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTAL 990
Query: 337 ERYQQLEEASASLRERI------------------------------RHLDDMVHCQQKK 366
E Q+ ++ +A + E R L+D++ +KK
Sbjct: 991 ELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKK 1050
Query: 367 VKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCD 403
+ Q EE E+ + + Q E++ + + GC+
Sbjct: 1051 LNQQAEELQEIH-EIQLQEKEQEVAELKQKILLFGCE 1086
Score = 58.5 bits (140), Expect = 1e-08
Identities = 81/409 (19%), Positives = 175/409 (42%), Gaps = 76/409 (18%)
Query: 33 LTVPPESPVPEQCEKKIERKEQLLDLSNGEPTRKLPQ---------------GVVYGVVR 77
L + + EQ +++++ E++ DL E T+ + Q G+V +
Sbjct: 311 LLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETK 370
Query: 78 RSD--------------QNQQKEMVVYGWSTSQLKE--------EMNYIKDVRATLEKVR 115
R +++ K+M G + KE E+ E+ R
Sbjct: 371 RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEAR 430
Query: 116 KRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQ 175
+++ + DE + I + ++E +S QQE + + +D M + LQ
Sbjct: 431 RKLKAEMDEQIKTIEKTSEEERIS-LQQEL----SRVKQEVVD---VMKKSSEEQIAKLQ 482
Query: 176 KTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVA--QVENQLLKMKVESSQEA 233
K + K+ R Q+ + + RE Q Q++VA + +++ LK+ E Q+
Sbjct: 483 KL---------HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQE 533
Query: 234 N--AEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEIS 291
+ E + K + ++ E KL++ Q++ + +LE +S K+++E + + +
Sbjct: 534 SLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVH 593
Query: 292 LE-EKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLR 350
LE EK++ E+ ++ E+H+ +L+ L+H+ + E+ Q L++ +
Sbjct: 594 LEAEKNKHNKEITVMV-----EKHKTELESLKHQQDALW------TEKLQVLKQQYQTEM 642
Query: 351 ERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTE-TQAKTEVETREI 398
E++R C+Q+K + ++ Q+ ++ + E T K +V+ E+
Sbjct: 643 EKLRE-----KCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTEL 686
Score = 55.1 bits (131), Expect = 1e-07
Identities = 63/315 (20%), Positives = 144/315 (45%), Gaps = 24/315 (7%)
Query: 96 QLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQE-----LSVSHAQQEYLENHI 150
QL+++ + ++ +L +V + D ++ +++ +Q+ E L + Q++ +E
Sbjct: 869 QLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILT 928
Query: 151 QTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQ 210
Q S+ D + +N + +K + V + +++ ++ EA + K E
Sbjct: 929 QKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENT 988
Query: 211 RQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEE 270
LE++Q E Q +E +Q AN+ + + +L + +E+++ H E ++
Sbjct: 989 A-LELSQKEKQFNAKMLEMAQ-ANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISI 1046
Query: 271 TNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLI-------ERMEKERHQLQLQLLEH 323
L ++A + + EI L+EK+Q + EL + I E M KE L+ + ++
Sbjct: 1047 WEKKLN--QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQ 1104
Query: 324 ETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDY 383
+T ++ EL + K++ + + + HL+ + + + + ++EN LQ +
Sbjct: 1105 DTTLN-ELQEQLKQKSAHVNSLAQDETKLKAHLEKL----EVDLNKSLKENTFLQ---EQ 1156
Query: 384 LTETQAKTEVETREI 398
L E + E + R++
Sbjct: 1157 LVELKMLAEEDKRKV 1171
Score = 55.1 bits (131), Expect = 1e-07
Identities = 83/390 (21%), Positives = 168/390 (43%), Gaps = 69/390 (17%)
Query: 38 ESPVPEQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVY------- 90
E V E + + +E+L+ L + E + Q ++ + ++ +K ++
Sbjct: 1760 EETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKE 1819
Query: 91 -GWSTSQLKEEM-NYIKDVRATLEKVRKRMYGDYDEMRQKIRQL----TQELSVSHAQQE 144
G + Q K+ + N DV+ TL++ + QKI++L ++ V + E
Sbjct: 1820 GGKNNIQAKQNLENVFDDVQKTLQEKELTC----QILEQKIKELDSCLVRQKEVHRVEME 1875
Query: 145 YLENHIQTQSSA--LDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEAS 202
L + + + +D N L ++ K+ + SN++ Q +L+ +
Sbjct: 1876 ELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1935
Query: 203 MDKLREKQRQ-LEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQY-EEKLQEEQR-- 258
REKQ+ E+ +++ L ++ E QE E+ KK Y Q EEK+++EQ
Sbjct: 1936 E---REKQKLGKEIVRLQKDLRMLRKEHQQEL------EILKKEYDQEREEKIKQEQEDL 1986
Query: 259 --KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQL 316
KH++ + L+ E N+ L +K+Q EL+ I+ + ++
Sbjct: 1987 ELKHNSTLKQLMREFNT-----------------QLAQKEQ---ELEMTIKETINKAQEV 2026
Query: 317 QLQLLEHETEMSGEL------TDSD----KERYQQL-----EEASASLRERIRHLDDMVH 361
+ +LLE E + +L D D +RY+++ EE +A +R+ L+++
Sbjct: 2027 EAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQK 2086
Query: 362 CQQKKVKQMVEENNELQSRLDYLTETQAKT 391
Q+K++Q N+ + ++ T+ KT
Sbjct: 2087 KYQQKLEQEENPGNDNVTIMELQTQLAQKT 2116
Score = 53.9 bits (128), Expect = 3e-07
Identities = 77/345 (22%), Positives = 150/345 (43%), Gaps = 45/345 (13%)
Query: 124 EMRQKIRQLTQE---LSVSHAQQ----EYLENHIQTQSSALDRFNAMNSALASDSIGLQK 176
E+ ++RQLT+E L++S Q E EN I++ + ++ AL + Q+
Sbjct: 1273 ELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQ 1332
Query: 177 TLVDVTLENSNIKDQIRNLQQTYEA-SMDKLREKQRQLEVAQVENQLLKMKVESSQEANA 235
+ + S I + L + A ++ K K++++E++ + QL + V+ +
Sbjct: 1333 AASE---KESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISL 1389
Query: 236 EVMREMTKKLYSQYEE---KLQEEQRKHSAEKEALLEETNSFLKAIEEANKKM----QAA 288
L QY+E +L ++ + S + + L +E S L+ +++ + K + A
Sbjct: 1390 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKA 1449
Query: 289 EISLEEKDQRIGELDRLIERMEKERHQL--QLQLLEHETE--------MSGELTDSDKER 338
+ + + EL +E KE ++ Q+ LL+ E + + GE+ D DK +
Sbjct: 1450 QSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMED-DKSK 1508
Query: 339 YQQ----LEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVE 394
++ LE S RI L+D H QK ++ +E NE+ + + + K V+
Sbjct: 1509 MEKKESNLETELKSQTARIMELED--HITQKTIE--IESLNEVLKNYNQQKDIEHKELVQ 1564
Query: 395 T----REIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLELTMKK 435
+E+G D ++ E ++ N Y+ EL KK
Sbjct: 1565 KLQHFQELGEEKD---NRVKEAEEKILTLENQV-YSMKAELETKK 1605
Score = 52.8 bits (125), Expect = 6e-07
Identities = 68/325 (20%), Positives = 147/325 (45%), Gaps = 23/325 (7%)
Query: 76 VRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEK-VRKRMYGDYDEMRQKIRQLTQ 134
+R+ + Q + + +T QL+E+ N IK ++A +E V ++ + Q+ +
Sbjct: 1278 LRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEK 1337
Query: 135 ELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRN 194
E ++ ++E EN + L + + S+ Q T ++V L+NS +
Sbjct: 1338 ESCITQLKKELSEN---INAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSE--- 1391
Query: 195 LQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQ 254
++ +S+ K ++++ + QV++ K+ S ++ +A + +S++++K Q
Sbjct: 1392 -KEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQ 1450
Query: 255 EEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERH 314
+H + L + LK+ +EA +K + + EE DQ+ D L ME ++
Sbjct: 1451 SRFTQHQNTVKELQIQLE--LKS-KEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKS 1507
Query: 315 QLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV--HCQQKKVKQMVE 372
+++ + ETE+ S R +LE+ I L++++ + QQK +
Sbjct: 1508 KMEKKESNLETELK-----SQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDI----- 1557
Query: 373 ENNELQSRLDYLTETQAKTEVETRE 397
E+ EL +L + E + + +E
Sbjct: 1558 EHKELVQKLQHFQELGEEKDNRVKE 1582
Score = 50.1 bits (118), Expect = 4e-06
Identities = 62/272 (22%), Positives = 123/272 (45%), Gaps = 18/272 (6%)
Query: 181 VTLENSNIKDQIRNLQQTYEASMD-KLREKQRQLEVAQVENQLLKMKVESSQEANAEVMR 239
+T E +++Q+ Q E D + EK + + + L++ + AE R
Sbjct: 312 LTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKR 371
Query: 240 EMTKKLYSQYEE--KLQEEQRKHSAEKEALLEETN-SFLKAIEEANKKMQAAEISLEEKD 296
+M + L + EE +L+ ++ + + E L E+ S A EE K + A+ + E +
Sbjct: 372 QMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARR 431
Query: 297 QRIGELDRLIERMEK----ERHQLQLQLLEHETEMSGELTDSDKERYQQLE-----EASA 347
+ E+D I+ +EK ER LQ +L + E+ + S +E+ +L+ E +
Sbjct: 432 KLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELAR 491
Query: 348 SLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPS 407
+E + L Q+++K +E++ ++ E Q +E E+ L S
Sbjct: 492 KEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTES 551
Query: 408 QTGRTREIVMPSRNYTPYTRVLEL--TMKKTL 437
+ + R++ + Y TR+LEL +++K+L
Sbjct: 552 E-NKLRDLQQEAETYR--TRILELESSLEKSL 580
Score = 49.7 bits (117), Expect = 5e-06
Identities = 53/269 (19%), Positives = 131/269 (48%), Gaps = 23/269 (8%)
Query: 95 SQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQS 154
S+ + N +K+++ LE K Y E ++I L +EL + + + L+ ++
Sbjct: 1451 SRFTQHQNTVKELQIQLELKSKEAY----EKDEQINLLKEELDQQNKRFDCLKGEMEDDK 1506
Query: 155 SALDRFNA-MNSALASDS---IGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQ 210
S +++ + + + L S + + L+ + T+E ++ + ++N Q + +L +K
Sbjct: 1507 SKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKL 1566
Query: 211 RQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEE 270
+ + +L + K +EA +++ + ++YS E E ++K ++
Sbjct: 1567 QHFQ------ELGEEKDNRVKEAEEKILT-LENQVYSMKAEL--ETKKKELEHVNLSVKS 1617
Query: 271 TNSFLKAIEEANKKMQAAEIS-LEEK-DQRIGELDR-LIERMEKERHQLQLQLLEHETEM 327
LKA+E+ + AA+++ L+ K +Q+I + + L+ +ME++ Q + H +E+
Sbjct: 1618 KEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSEL 1677
Query: 328 SGELTDSDKERY---QQLEEASASLRERI 353
+ +L + ++E + ++L+ +S E +
Sbjct: 1678 NTKLQEREREVHILEEKLKSVESSQSETL 1706
Score = 45.4 bits (106), Expect = 1e-04
Identities = 65/289 (22%), Positives = 124/289 (42%), Gaps = 25/289 (8%)
Query: 123 DEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTL--VD 180
+EM ++I L +E +Q+ N +Q Q L + +A ++LA D L+ L ++
Sbjct: 1088 EEMNKEITWLKEE----GVKQDTTLNELQEQ---LKQKSAHVNSLAQDETKLKAHLEKLE 1140
Query: 181 VTL-----ENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANA 235
V L EN+ +++Q+ L+ E K+ E +L+ E Q LK E S ++
Sbjct: 1141 VDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1200
Query: 236 EVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEE--------TNSFLKAIEEANKKMQA 287
+ E KKL + +L +K A EA E TN+ L I +
Sbjct: 1201 DKSLEF-KKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTK 1259
Query: 288 AEISLEEKDQRIGELDRLIERMEKERHQLQL--QLLEHETEMSGELTDSDKERYQQLEEA 345
+ +L K + EL+ + ++ +E++ L + Q H+ E S K + L
Sbjct: 1260 VKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTE 1319
Query: 346 SASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVE 394
+L++ + ++ + Q+ +E +E + + + E + +VE
Sbjct: 1320 KEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVE 1368
Score = 42.4 bits (98), Expect = 8e-04
Identities = 78/372 (20%), Positives = 149/372 (40%), Gaps = 66/372 (17%)
Query: 75 VVRRSDQN-----QQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRM-------YGDY 122
+V RS +N +Q+E G +E+++ ++ EK+ +R+ +
Sbjct: 1707 IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSH 1766
Query: 123 DEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQ--KTLVD 180
EMR + ++ +L + A+Q ++ I L+ N S + + + + K +
Sbjct: 1767 FEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQ 1826
Query: 181 VTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMRE 240
N+ D ++ Q E + L +K ++L+ V + EV R
Sbjct: 1827 AKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQK--------------EVHRV 1872
Query: 241 MTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG 300
++L S+YE KLQ L+ ++ NK + E + EEK +
Sbjct: 1873 EMEELTSKYE-KLQA-------------------LQQMDGRNKPTELLEENTEEKSKSHL 1912
Query: 301 ELDRLIERMEKERHQLQLQLLEHETE----------MSGELTDSDKERYQQLE----EAS 346
+L+ ME + + L+ +L E E + +L KE Q+LE E
Sbjct: 1913 VQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYD 1972
Query: 347 ASLRERIR-HLDDMVHCQQKKVKQMVEE-NNELQSRLDYLTETQAKTEVETREIGVGCDL 404
E+I+ +D+ +KQ++ E N +L + L T +T + +E V +L
Sbjct: 1973 QEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQE--VEAEL 2030
Query: 405 LPSQTGRTREIV 416
L S T +++
Sbjct: 2031 LESHQEETNQLL 2042
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 72.0 bits (175), Expect = 1e-12
Identities = 82/352 (23%), Positives = 142/352 (40%), Gaps = 32/352 (9%)
Query: 76 VRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQE 135
++R Q +KE + + M I +A LEK+ + + +E R K + +
Sbjct: 1210 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRS 1269
Query: 136 LSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTL---ENSNIKDQI 192
++ +Q+ L+ S LD A+ S L + + L D+ E K+ +
Sbjct: 1270 VNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKAKNAL 1329
Query: 193 RN-----------LQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREM 241
+ L++ YE + E QR L A E + K E+ E + E
Sbjct: 1330 AHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1389
Query: 242 TKKLYSQYEE-------------KLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAA 288
KKL + +E L++ + + E E L+ + A +KK +
Sbjct: 1390 KKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF 1449
Query: 289 EISLEEKDQRIGELDRLIERMEKERHQLQLQL--LEHETEMSGELTDSDKERYQQLEEAS 346
+ L E Q+ E +E +KE L +L L++ E S E ++ K + L+E
Sbjct: 1450 DKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEI 1509
Query: 347 ASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREI 398
+ L E++ +H +K KQ+ E ELQS L+ E +A E E +I
Sbjct: 1510 SDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSALE---EAEASLEHEEGKI 1558
Score = 60.8 bits (146), Expect = 2e-09
Identities = 67/335 (20%), Positives = 147/335 (43%), Gaps = 47/335 (14%)
Query: 97 LKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSA 156
L+ + K VR LE+ ++++ GD ++ I L + ++ L+ ++ +
Sbjct: 1034 LEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEND-------KQQLDERLKKKDFE 1086
Query: 157 LDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLR-EKQRQLEV 215
L+ NA + LQK L ++ +++++ ++T A ++KLR + R+LE
Sbjct: 1087 LNALNARIEDEQALGSQLQKKLKELQARIEELEEELE-AERTARAKVEKLRSDLSRELE- 1144
Query: 216 AQVENQL--------LKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL 267
++ +L +++++ +EA + MR ++ Q+E ++KH+ L
Sbjct: 1145 -EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAEL 1203
Query: 268 LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHE--- 324
E+ ++ + ++ K+ ++ L++ + ++ + +EK L+ Q+ EH
Sbjct: 1204 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKA 1263
Query: 325 ----------TEMSGELTDSDKERYQQLEEASASLRERIR-------HLDDMVHCQQKKV 367
T +L + E +QL+E A + + R L+D+ +++V
Sbjct: 1264 EETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEV 1323
Query: 368 KQMVEENNELQS--------RLDYLTETQAKTEVE 394
K + LQS R Y ET+AK E++
Sbjct: 1324 KAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Score = 60.5 bits (145), Expect = 3e-09
Identities = 73/343 (21%), Positives = 141/343 (41%), Gaps = 48/343 (13%)
Query: 84 QKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQ 143
QK++ +L+EE+ + RA +EK+R + + +E+ +++ + SV
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 1164
Query: 144 EYLENHIQTQSSALDRFNAMNSALA-------SDSI--------GLQKTLVDVTLENSNI 188
+ E Q L+ + A A +DS+ LQ+ + E S
Sbjct: 1165 KKREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEF 1224
Query: 189 K----DQIRNLQQTYEASM----------DKLREKQRQLEVAQVENQLLKMKVESSQEAN 234
K D N++Q +A D++ E + + E Q L + Q N
Sbjct: 1225 KLELDDVTSNMEQIIKAKANLEKMCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTEN 1284
Query: 235 AEVMREMTKK--LYSQ-------YEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKM 285
E+ R++ +K L SQ Y ++L++ +R+ E +A N+ A++ A
Sbjct: 1285 GELSRQLDEKEALISQLTRGKLTYTQQLEDLKRQLEEEVKA----KNALAHALQSARHDC 1340
Query: 286 QAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDK---ERYQQL 342
EE+ + EL R++ + E Q + + + + EL ++ K +R Q+
Sbjct: 1341 DLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEA 1400
Query: 343 EEASASLRERIRHLDDMVHCQQKKVKQM---VEENNELQSRLD 382
EEA ++ + L+ H Q +++ + VE +N + LD
Sbjct: 1401 EEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALD 1443
Score = 57.0 bits (136), Expect = 3e-08
Identities = 62/286 (21%), Positives = 129/286 (45%), Gaps = 31/286 (10%)
Query: 109 ATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALA 168
A L+K ++ E +QK + EL S + L + +A +
Sbjct: 1440 AALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFK 1499
Query: 169 SDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVE 228
++ LQ+ + D+T +Q+ + +T + +L + ++QLE ++E Q
Sbjct: 1500 RENKNLQEEISDLT-------EQLGSSGKT----IHELEKVRKQLEAEKMELQ------S 1542
Query: 229 SSQEANAEVMREMTKKLYSQYE-EKLQEEQRKHSAEKEALLEET-NSFLKAIEEANKKMQ 286
+ +EA A + E K L +Q E +++ E + AEK+ +E+ + L+ ++
Sbjct: 1543 ALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVD------- 1595
Query: 287 AAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEAS 346
+ + SL+ + + E R+ ++ME + +++++Q L H M+ E K L++
Sbjct: 1596 SLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ-LSHANRMAAEAQKQVKSLQSLLKDTQ 1654
Query: 347 ASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTE 392
L + +R DD+ ++ + + NN LQ+ L+ L +TE
Sbjct: 1655 IQLDDAVRANDDL----KENIAIVERRNNLLQAELEELRAVVEQTE 1696
Score = 53.1 bits (126), Expect = 5e-07
Identities = 72/333 (21%), Positives = 141/333 (42%), Gaps = 56/333 (16%)
Query: 113 KVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSI 172
+V+K+M GD +EM E+ +SHA + E Q +S + S L I
Sbjct: 1613 RVKKKMEGDLNEM---------EIQLSHANRMAAEAQKQVKS--------LQSLLKDTQI 1655
Query: 173 GLQKTLVDVTLENSNIKDQIRNLQQT---YEASMDKLREKQRQLEVAQ--VENQLLKM-- 225
L D N ++K+ I +++ +A +++LR Q E ++ E +L++
Sbjct: 1656 QLD----DAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSE 1711
Query: 226 KVESSQEANAEVMREMTK------KLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIE 279
+V+ N ++ + K +L ++ EE +QE + K+A+ T++ + A E
Sbjct: 1712 RVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAI---TDAAMMAEE 1768
Query: 280 EANKKMQAAEISLEEK--DQRIGELDRLIERME--------KERHQLQLQLLEHETEMSG 329
++ +A + +K +Q I +L ++ E K+ +L+ ++ E E E+
Sbjct: 1769 LKKEQDTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEA 1828
Query: 330 ELTDS---------DKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSR 380
E + + R ++L + R+ + L D+V Q KVK + E + +
Sbjct: 1829 EQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQ 1888
Query: 381 LDYLTETQAKTEVETREIGVGCDLLPSQTGRTR 413
+ K + E E D+ SQ + R
Sbjct: 1889 ANTNLSKFRKVQHELDEAEERADIAESQVNKLR 1921
Score = 51.2 bits (121), Expect = 2e-06
Identities = 61/301 (20%), Positives = 132/301 (43%), Gaps = 20/301 (6%)
Query: 95 SQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQS 154
+ +KEE +K+ E RK E+ +K+ L QE + Q + ++++
Sbjct: 850 ASMKEEFTRLKEALEKSEARRK-------ELEEKMVSLLQEKNDLQLQVQAEQDNLADAE 902
Query: 155 SALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLE 214
D+ L + + + L D N+ + + R L+ + + + L
Sbjct: 903 ERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDIDDLELTLA 962
Query: 215 VAQVENQLLKMKVESSQEANA---EVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEET 271
+ E + KV++ E A E++ ++TK+ ++ LQE ++ + +A ++
Sbjct: 963 KVEKEKHATENKVKNLTEEMAGLDEIIAKLTKE-----KKALQEAHQQALDDLQAEEDKV 1017
Query: 272 NSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGEL 331
N+ KA + +++ E SLE++ + +L+R ++E + Q +++ E + +L
Sbjct: 1018 NTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKQ-QL 1076
Query: 332 TDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKT 391
+ K++ +L +L RI + QKK+K++ EL+ L+ +AK
Sbjct: 1077 DERLKKKDFELN----ALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKV 1132
Query: 392 E 392
E
Sbjct: 1133 E 1133
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 8/134 (5%)
Query: 261 SAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQL 320
SAE+E + ++EA +K +A LEEK + L++ EK QLQ+Q
Sbjct: 842 SAEREKEMASMKEEFTRLKEALEKSEARRKELEEK------MVSLLQ--EKNDLQLQVQA 893
Query: 321 LEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSR 380
+ + E D + QLE + ER+ ++M K +++ +E +EL+
Sbjct: 894 EQDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRD 953
Query: 381 LDYLTETQAKTEVE 394
+D L T AK E E
Sbjct: 954 IDDLELTLAKVEKE 967
Score = 34.7 bits (78), Expect = 0.18
Identities = 32/182 (17%), Positives = 76/182 (41%), Gaps = 7/182 (3%)
Query: 77 RRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQ-E 135
R +++ +K + +LK+E +D A LE+++K M +++ ++ + Q
Sbjct: 1749 RNAEEKAKKAITDAAMMAEELKKE----QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1804
Query: 136 LSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNL 195
L Q + LE ++ + L+ N+ ++ + ++T + + + L
Sbjct: 1805 LKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRL 1864
Query: 196 QQTYEASMDKLREKQRQLEVA--QVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKL 253
Q + K++ +RQ E A Q L K + + AE ++ + ++ K
Sbjct: 1865 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1924
Query: 254 QE 255
++
Sbjct: 1925 RD 1926
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 71.6 bits (174), Expect = 1e-12
Identities = 85/352 (24%), Positives = 143/352 (40%), Gaps = 32/352 (9%)
Query: 76 VRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQE 135
++R Q +KE + + M I +A LEKV + + +E R K+ + +
Sbjct: 1212 LQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRS 1271
Query: 136 LSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTL---ENSNIKDQI 192
L+ Q+ L+ + L+ A+ S L + + + D+ E K+ +
Sbjct: 1272 LNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNAL 1331
Query: 193 RN-----------LQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREM 241
+ L++ YE + E QR L A E + K E+ E + E
Sbjct: 1332 AHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA 1391
Query: 242 TKKLYSQY---EEKLQEEQRKHSA---EKEALLEETNSFLKAIEEAN-------KKMQAA 288
KKL + EE ++ K S+ K L E + +E +N KK +
Sbjct: 1392 KKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNF 1451
Query: 289 EISLEEKDQRIGELDRLIERMEKERHQLQLQL--LEHETEMSGELTDSDKERYQQLEEAS 346
+ L E Q+ E +E +KE L +L L++ E S E ++ K + L+E
Sbjct: 1452 DKILAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEI 1511
Query: 347 ASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREI 398
+ L E++ VH +K KQ+ E ELQS L+ E +A E E +I
Sbjct: 1512 SDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALE---EAEASLEHEEGKI 1560
Score = 64.3 bits (155), Expect = 2e-10
Identities = 77/372 (20%), Positives = 174/372 (46%), Gaps = 42/372 (11%)
Query: 43 EQCEKKIERKEQL---LDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKE 99
EQ E++ E K +L L +N E + + + R + + K+ + ++ E
Sbjct: 1347 EQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAE--E 1404
Query: 100 EMNYIKDVRATLEKVRKRMYGDYDEMRQKI------------RQLTQELSVSHAQQEYLE 147
+ + ++LEK + R+ + +++ + +Q + ++ +Q+Y E
Sbjct: 1405 AVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEE 1464
Query: 148 NHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTL---ENSNIKDQIRNL-QQTYEA-- 201
+ + +SS + ++++ L +++L + EN N++++I +L +Q E
Sbjct: 1465 SQSELESSQKEA-RSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGK 1523
Query: 202 SMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYE-EKLQEEQRKH 260
++ +L + ++QLEV ++E Q + +EA A + E K L +Q E +++ E +
Sbjct: 1524 NVHELEKVRKQLEVEKLELQ------SALEEAEASLEHEEGKILRAQLEFNQIKAEIERK 1577
Query: 261 SAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQL 320
AEK+ +E+ A + + + + SL+ + + E+ R+ ++ME + +++++Q
Sbjct: 1578 LAEKDEEMEQ------AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQ- 1630
Query: 321 LEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSR 380
L H M+ E K L++ L + +R DD+ ++ + + NN LQ+
Sbjct: 1631 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDL----KENIAIVERRNNLLQAE 1686
Query: 381 LDYLTETQAKTE 392
L+ L +TE
Sbjct: 1687 LEELRAVVEQTE 1698
Score = 55.8 bits (133), Expect = 7e-08
Identities = 76/358 (21%), Positives = 157/358 (43%), Gaps = 50/358 (13%)
Query: 80 DQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIR---QLTQEL 136
D Q +E V S S++K E + D+ +LE+ K++ D + ++K+ +LTQE
Sbjct: 1010 DDLQVEEDKVNSLSKSKVKLEQQ-VDDLEGSLEQ-EKKVRMDLERAKRKLEGDLKLTQE- 1066
Query: 137 SVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSI---GLQKTLVDVTLENSNIKDQIR 193
S+ + + L+ + + D N NS + + + LQK L + +++++
Sbjct: 1067 SIMDLENDKLQLEEKLKKKEFD-INQQNSKIEDEQVLALQLQKKLKENQARIEELEEELE 1125
Query: 194 NLQQTYEASMDKLR-EKQRQLEVAQVENQL--------LKMKVESSQEANAEVMREMTKK 244
++T A ++KLR + R+LE ++ +L +++++ +EA + MR ++
Sbjct: 1126 -AERTARAKVEKLRSDLSRELE--EISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEE 1182
Query: 245 LYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDR 304
Q+E ++KH+ L E+ ++ + ++ K+ ++ L++ + ++ +
Sbjct: 1183 ATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIK 1242
Query: 305 LIERMEKERHQLQLQLLEHE-------------TEMSGELTDSDKERYQQLEEASASLRE 351
+EK L+ Q E+ T +L + E +QLEE A + +
Sbjct: 1243 AKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQ 1302
Query: 352 RIRHLDDMVHCQQKKVKQMVEEN-------NELQS--------RLDYLTETQAKTEVE 394
R + +Q+ EE + LQS R Y ET+AK E++
Sbjct: 1303 LTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1360
Score = 54.7 bits (130), Expect = 2e-07
Identities = 74/310 (23%), Positives = 138/310 (44%), Gaps = 54/310 (17%)
Query: 97 LKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIR----QLTQELSVSHAQQEYLENHIQT 152
L+E+ + +A L++V + + + R K Q T+EL + ++ L +Q
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEA---KKKLAQRLQD 1401
Query: 153 QSSALDRFNAMNSALASDSIGLQKTLVD--VTLENSNIKDQIRNLQQTYEASMDK-LREK 209
A++ NA S+L LQ + D V +E SN + +Q + DK L E
Sbjct: 1402 AEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQR---NFDKILAEW 1458
Query: 210 QRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLE 269
+++ E +Q E +ESSQ+ + E+ K L + YEE L+
Sbjct: 1459 KQKYEESQSE-------LESSQKEARSLSTELFK-LKNAYEESLEH-------------- 1496
Query: 270 ETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLE-----HE 324
L+ + NK +Q + + +++GE + + +EK R QL+++ LE E
Sbjct: 1497 -----LETFKRENKNLQE---EISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSALEE 1548
Query: 325 TEMSGELTDSDKERYQ-QLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDY 383
E S E + R Q + + A + ++ D+ + ++ +++V+ LQ+ LD
Sbjct: 1549 AEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVD---SLQTSLD- 1604
Query: 384 LTETQAKTEV 393
ET+++ EV
Sbjct: 1605 -AETRSRNEV 1613
Score = 54.3 bits (129), Expect = 2e-07
Identities = 68/320 (21%), Positives = 140/320 (43%), Gaps = 30/320 (9%)
Query: 113 KVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSI 172
+V+K+M GD +EM ++ + + + Q + L++ ++ LD ++ A+D
Sbjct: 1615 RVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLD-----DAVRANDD- 1668
Query: 173 GLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQE 232
L++ + V N+ ++ ++ L+ E + + +++L QLL + S
Sbjct: 1669 -LKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLIN 1727
Query: 233 ANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISL 292
++ ++T +L S+ EE +QE + K+A+ T++ + A E ++ +A +
Sbjct: 1728 QKKKMESDLT-QLQSEVEEAVQECRNAEEKAKKAI---TDAAMMAEELKKEQDTSAHLER 1783
Query: 293 EEK--DQRIGELDRLIERMEK---ERHQLQLQLLEHET-EMSGELTDSDK---------- 336
+K +Q I +L ++ E+ + + QLQ LE E+ GEL K
Sbjct: 1784 MKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMR 1843
Query: 337 ---ERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEV 393
R ++L + ++ + L D+V Q KVK + E + + + K +
Sbjct: 1844 KSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQH 1903
Query: 394 ETREIGVGCDLLPSQTGRTR 413
E E D+ SQ + R
Sbjct: 1904 ELDEAEERADIAESQVNKLR 1923
Score = 50.8 bits (120), Expect = 2e-06
Identities = 45/221 (20%), Positives = 106/221 (47%), Gaps = 19/221 (8%)
Query: 184 ENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTK 243
E + +K++ +++T E S + +E + ++ E L+++V++ Q+ N E
Sbjct: 850 EMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQD-NLNDAEERCD 908
Query: 244 KLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEK----DQRI 299
+L K+ + EA ++E N L+ EE N ++ A + LE++ + I
Sbjct: 909 QLI------------KNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDI 956
Query: 300 GELDRLIERMEKERHQLQLQLLEHETEMSG--ELTDSDKERYQQLEEASASLRERIRHLD 357
+L+ + ++EKE+H + ++ EM+G E+ + + L+EA + ++ +
Sbjct: 957 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVEE 1016
Query: 358 DMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREI 398
D V+ K ++ ++ ++L+ L+ + + E R++
Sbjct: 1017 DKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKL 1057
Score = 48.5 bits (114), Expect = 1e-05
Identities = 60/300 (20%), Positives = 134/300 (44%), Gaps = 22/300 (7%)
Query: 97 LKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSA 156
+KEE IK+ TLEK R E+ +K+ L QE + Q + ++++
Sbjct: 854 MKEEFGRIKE---TLEKSEARR----KELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEER 906
Query: 157 LDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVA 216
D+ L + + + L D N+ + + R L+ + + + L
Sbjct: 907 CDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKV 966
Query: 217 QVENQLLKMKVESSQEANA---EVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNS 273
+ E + KV++ E A E++ ++TK+ ++ LQE ++ + + ++ NS
Sbjct: 967 EKEKHATENKVKNLTEEMAGLDEIIAKLTKE-----KKALQEAHQQALDDLQVEEDKVNS 1021
Query: 274 FLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTD 333
K+ + +++ E SLE++ + +L+R ++E + Q +++ E + +L +
Sbjct: 1022 LSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKL-QLEE 1080
Query: 334 SDKERYQQLEEASASLRERIRHLDDMVHCQ-QKKVKQMVEENNELQSRLDYLTETQAKTE 392
K++ + + ++ + + + ++ Q QKK+K+ EL+ L+ +AK E
Sbjct: 1081 KLKKKEFDINQQNSKIED-----EQVLALQLQKKLKENQARIEELEEELEAERTARAKVE 1135
Score = 39.3 bits (90), Expect = 0.007
Identities = 67/285 (23%), Positives = 117/285 (41%), Gaps = 39/285 (13%)
Query: 118 MYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQS--SALD------RFNAMNSALAS 169
+YGD+ RQ+ R L V+ + +++++ T+ S+LD +F +
Sbjct: 716 LYGDF---RQRYRILNP---VAIPEGQFIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKA 769
Query: 170 DSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVES 229
+GL + + D L + Q + Q K+ E++ L V ++
Sbjct: 770 GLLGLLEEMRDERLSRIITRMQAQARGQLMRIEFKKIVERRDALLV-----------IQW 818
Query: 230 SQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAE 289
+ A V KLY + + L+ SAE E + I+E +K +A
Sbjct: 819 NIRAFMGVKNWPWMKLYFKIKPLLK------SAETEKEMATMKEEFGRIKETLEKSEARR 872
Query: 290 ISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASL 349
LEEK + L++ EK QLQ+Q + + E D + QLE +
Sbjct: 873 KELEEK------MVSLLQ--EKNDLQLQVQAEQDNLNDAEERCDQLIKNKIQLEAKVKEM 924
Query: 350 RERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVE 394
ER+ ++M K +++ +E +EL+ +D L T AK E E
Sbjct: 925 NERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKE 969
Score = 37.4 bits (85), Expect = 0.027
Identities = 39/194 (20%), Positives = 81/194 (41%), Gaps = 12/194 (6%)
Query: 77 RRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQ-E 135
R +++ +K + +LK+E +D A LE+++K M +++ ++ + Q
Sbjct: 1751 RNAEEKAKKAITDAAMMAEELKKE----QDTSAHLERMKKNMEQTIKDLQHRLDEAEQIA 1806
Query: 136 LSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNL 195
L Q + LE ++ L+ N+ ++ + ++T + K + L
Sbjct: 1807 LKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKSERRIKELTYQTEEDKKNLLRL 1866
Query: 196 QQTYEASMDKLREKQRQLEVA--QVENQLLKM-KVE---SSQEANAEVMREMTKKLYSQY 249
Q + K++ +RQ E A Q L K KV+ E A++ KL ++
Sbjct: 1867 QDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAKS 1926
Query: 250 EEKLQEEQRKHSAE 263
+ + +Q+ H E
Sbjct: 1927 RD-IGAKQKMHDEE 1939
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 71.2 bits (173), Expect = 2e-12
Identities = 80/378 (21%), Positives = 180/378 (47%), Gaps = 52/378 (13%)
Query: 30 RLRLTVPPESPVPEQCEKKIER-----KEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQ 84
RL+ T +S ++ E+++E KEQ + ++N T++L Q + D QQ
Sbjct: 1579 RLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITN--LTQQLEQASIVKKRSEDDLRQQ 1636
Query: 85 KEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQE 144
++++ ++++ + T E++R R+ + + +R+++ Q + + +H + E
Sbjct: 1637 RDVLD------------GHLREKQRTQEELR-RLSSEVEALRRQLLQEQESVKQAHLRNE 1683
Query: 145 YLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTY----- 199
+ + I+ +S +L+ + LQ ++T E+ +++++RNL+ Y
Sbjct: 1684 HFQKAIEDKSRSLNESKI-------EIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRR 1736
Query: 200 ---EASMDK---LREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTK--KLYSQYEE 251
EA DK + E + QL+++ L+ + Q + +E+ K K +
Sbjct: 1737 GRSEADSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASN 1796
Query: 252 KLQEEQRKHSA---EKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIER 308
++QE + + + E+E+LL + +K +E+ ++Q E L + R+ +R
Sbjct: 1797 RIQESKNQCTQVVQERESLLVK----IKVLEQDKARLQRLEDELNRAKSTLEAETRVKQR 1852
Query: 309 MEKERHQLQLQLLEHETEMSGE---LTDSDKERYQQLEEASASLRERIRHLDDMVHCQQK 365
+E E+ Q+Q L + +T+ S + + + ER ++ E SLR I L + ++
Sbjct: 1853 LECEKQQIQNDLNQWKTQYSRKEEAIRKIESER-EKSEREKNSLRSEIERLQAEIKRIEE 1911
Query: 366 KVKQMVEEN-NELQSRLD 382
+ ++ +E++ E QS+L+
Sbjct: 1912 RCRRKLEDSTRETQSQLE 1929
Score = 59.7 bits (143), Expect = 5e-09
Identities = 69/316 (21%), Positives = 147/316 (46%), Gaps = 44/316 (13%)
Query: 80 DQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRK-------RMYGDYDEMRQKIRQL 132
DQN QK Y SQ K ++ +++++ E K + YG E+ +KI +L
Sbjct: 1059 DQNLQK----YQAECSQFKAKLASLEELKRQAELDGKSAKQNLDKCYGQIKELNEKITRL 1114
Query: 133 TQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIK-DQ 191
T E+ +++ +E+ Q + D+ +++G QK + ++ + ++
Sbjct: 1115 TYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQC-EKENLGWQKLESEKAIKEKEYEIER 1173
Query: 192 IRNLQQTYEASMDKLREKQRQLEVAQVENQLLK--MKVESSQEANAEVMREMTKKLYSQY 249
+R L Q + R+++ + E+A+V N + + + E + + K++ Q
Sbjct: 1174 LRVLLQE-----EGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKTTIKEISMQK 1228
Query: 250 EE-------KLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGEL 302
E+ +L R++ K+ ++ +S L+A E+ + +A E +L++K G
Sbjct: 1229 EDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQ---RRRAEENALQQK--ACGS- 1282
Query: 303 DRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQ-LEEASASLRERIRHLDDMVH 361
E M+K++H LE E + + D R++Q LEEA+ +++++ + ++ +
Sbjct: 1283 ----EIMQKKQH------LEIELKQVMQQRSEDNARHKQSLEEAAKTIQDKNKEIERLKA 1332
Query: 362 CQQKKVKQMVEENNEL 377
Q++ K+ E NEL
Sbjct: 1333 EFQEEAKRRWEYENEL 1348
Score = 57.8 bits (138), Expect = 2e-08
Identities = 69/326 (21%), Positives = 143/326 (43%), Gaps = 47/326 (14%)
Query: 81 QNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSH 140
QN KE+ + +++EE+N +K + RK++ + + MR+ +++ Q + +++
Sbjct: 1560 QNSLKELQL---QKQKVEEELNRLKRTASEDSCKRKKLEEELEGMRRSLKE--QAIKITN 1614
Query: 141 AQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTL-ENSNIKDQIRNLQQTY 199
Q+ + I + S D + Q+ ++D L E ++++R L
Sbjct: 1615 LTQQLEQASIVKKRS-------------EDDLRQQRDVLDGHLREKQRTQEELRRLSSEV 1661
Query: 200 EASMDKLREKQRQLEVAQVENQLLKMKVE----SSQEANAEVMR--EMTKKLYSQYEEKL 253
EA +L ++Q ++ A + N+ + +E S E+ E+ R +T+ L ++ L
Sbjct: 1662 EALRRQLLQEQESVKQAHLRNEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHL-ML 1720
Query: 254 QEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKER 313
+EE R E + L + +A + N + L+ + R EL LI +++ER
Sbjct: 1721 EEELRNLRLEYDDLRRGRS---EADSDKNATILELRSQLQISNNRTLELQGLINDLQRER 1777
Query: 314 HQLQLQLLEHET---EMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQM 370
L+ ++ + + E S + +S + Q ++E + L K+K +
Sbjct: 1778 ENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLL---------------VKIKVL 1822
Query: 371 VEENNELQSRLDYLTETQAKTEVETR 396
++ LQ D L ++ E ETR
Sbjct: 1823 EQDKARLQRLEDELNRAKSTLEAETR 1848
Score = 54.7 bits (130), Expect = 2e-07
Identities = 78/372 (20%), Positives = 161/372 (43%), Gaps = 65/372 (17%)
Query: 47 KKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGW--STSQLKEEMNYI 104
K+IER +QL+D + RK + D+N + + V Y + S E +N +
Sbjct: 1481 KEIERLKQLIDKETND--RKCLE----------DENARLQRVQYDLQKANSSATETINKL 1528
Query: 105 KDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMN 164
K L ++R DY+ + Q+ + ++ ++ Q E +Q Q + N +
Sbjct: 1529 KVQEQELTRLRI----DYERVSQE--RTVKDQDITRFQNSLKELQLQKQKVE-EELNRLK 1581
Query: 165 SALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLK 224
+ DS +K +++++ ++++ + K+ +QLE A + +K
Sbjct: 1582 RTASEDSCKRKK-----------LEEELEGMRRSLKEQAIKITNLTQQLEQASI----VK 1626
Query: 225 MKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKK 284
+ E +V+ ++ +++ QEE R+ S+E EAL + +++++A+ +
Sbjct: 1627 KRSEDDLRQQRDVLDGHLRE-----KQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLR 1681
Query: 285 MQAAEISLEEKDQRIGE-------LDRLIERMEKERHQLQLQL----LEHETEMSGEL-T 332
+ + ++E+K + + E L L E + KE L+ +L LE++ G
Sbjct: 1682 NEHFQKAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRRGRSEA 1741
Query: 333 DSDK-----ERYQQLE-------EASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSR 380
DSDK E QL+ E + + R +++ +K KQ +E +N +Q
Sbjct: 1742 DSDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQES 1801
Query: 381 LDYLTETQAKTE 392
+ T+ + E
Sbjct: 1802 KNQCTQVVQERE 1813
Score = 48.9 bits (115), Expect = 9e-06
Identities = 53/268 (19%), Positives = 120/268 (44%), Gaps = 33/268 (12%)
Query: 81 QNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSH 140
Q + +MV +G + +++ +N + + ++ GDY KI+ +E S +
Sbjct: 198 QRAEMDMVAWGVDLASVEQHINSHRGIHNSI--------GDYRWQLDKIKADLREKSAIY 249
Query: 141 AQQEYLENHIQTQSSALDRFNAMNSALASDSIGL--------QKTLVDVTLENSNIKDQI 192
+E EN ++ +D + + + + S + ++ L D + +N+NI +
Sbjct: 250 QLEEEYENLLKASFERMDHLRQLQNIIQATSREIMWINDCEEEELLYDWSDKNTNIAQK- 308
Query: 193 RNLQQTYEASMDKLREKQRQL-EVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEE 251
Q+ + M +L K+++L ++ Q +QL+ + +S + A + T+ +
Sbjct: 309 ---QEAFSIRMSQLEVKEKELNKLKQESDQLVLNQHPASDKIEAYMDTLQTQWSWILQIT 365
Query: 252 KLQEEQRKHSAEKEALLEE---TNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIER 308
K + K +A EE T ++LK ++++ +K +K+ + L I+
Sbjct: 366 KCIDVHLKENAAYFQFFEEAQSTEAYLKGLQDSIRKKYPC-----DKNMPLQHLLEQIKE 420
Query: 309 MEKERHQLQLQLLEHETEMSGELTDSDK 336
+EKER ++LE++ ++ + S K
Sbjct: 421 LEKERE----KILEYKRQVQNLVNKSKK 444
Score = 40.0 bits (92), Expect = 0.004
Identities = 53/254 (20%), Positives = 104/254 (40%), Gaps = 36/254 (14%)
Query: 180 DVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLE----VAQVENQLLKMKVESSQEANA 235
D EN N + Q Y+A + + K LE A+++ + K ++
Sbjct: 1046 DANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQAELDGKSAKQNLDKCYGQIK 1105
Query: 236 EVMREMTKKLYSQYEEKLQEE----------------QRKHSAEKEALLEETNSFLKAIE 279
E+ ++T+ Y +EK + + Q+ EKE L + KAI+
Sbjct: 1106 ELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIK 1165
Query: 280 EANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLL-EHETEMSGELTDSDKER 338
E +++ + L+E+ R E + + ++ ++ L ++ETE++ T + KE
Sbjct: 1166 EKEYEIERLRVLLQEEGTRKREYENELAKVRNHYNEEMSNLRNKYETEINITKT-TIKEI 1224
Query: 339 YQQLEEASASLRERI-------RHLDDMVHCQQKKVKQMVE-----ENNELQSRL--DYL 384
Q E+ S +LR ++ R L D + + Q E E N LQ + +
Sbjct: 1225 SMQKEDDSKNLRNQLDRLSRENRDLKDEIVRLNDSILQATEQRRRAEENALQQKACGSEI 1284
Query: 385 TETQAKTEVETREI 398
+ + E+E +++
Sbjct: 1285 MQKKQHLEIELKQV 1298
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 71.2 bits (173), Expect = 2e-12
Identities = 81/382 (21%), Positives = 158/382 (41%), Gaps = 41/382 (10%)
Query: 49 IERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVR 108
+E+ ++ + L E R L + + + + ++ Q+KE V + LKEE+ +K
Sbjct: 186 MEKSDEFICLLEQECER-LKKLIDQEIKSQEEKEQEKEKRV-----TTLKEELTKLKSFA 239
Query: 109 ATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALA 168
+ ++R+ RQKI++LT +H + E +Q + R + L
Sbjct: 240 LMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATR---LEKELQ 296
Query: 169 SDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEA---SMDKLREKQRQLEVAQVENQLLKM 225
+ + + + + +N Q R LQQ A +D+L E R L A+ E Q +K
Sbjct: 297 TQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKE 356
Query: 226 KVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKM 285
K+ + NA +M E+ EE RK + E EE + + NK++
Sbjct: 357 KISKGEYGNAGIMAEV-------------EELRKRVLDMEGKDEELIKMEEQCRDLNKRL 403
Query: 286 QAA-------EISLEEKDQRIGELDRLIERMEKERHQ-----LQLQLLEHETEMSGELTD 333
+ ++ +E+ +RI L++L + K + + L+ T+ + +
Sbjct: 404 ERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELE 463
Query: 334 SDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRL----DYLTETQA 389
S K R ++LE + L + L + + + V+E + +L D L +
Sbjct: 464 SLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASS 523
Query: 390 KTEVETREIGVGCDLLPSQTGR 411
+ +VE ++ + L +T R
Sbjct: 524 QLQVEQNKVTTVTEKLIEETKR 545
Score = 58.5 bits (140), Expect = 1e-08
Identities = 66/330 (20%), Positives = 141/330 (42%), Gaps = 39/330 (11%)
Query: 96 QLKEEMNYIKDVRATLEKVRKRMYG------DYDEMRQKIRQLTQELSVSHAQQEYLENH 149
+L+ E KD + +EK+ KR+ +++ +Q+ L L + L
Sbjct: 402 RLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQE 461
Query: 150 IQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREK 209
+++ + A+ S L L++ L + D+ + + + + + DKL+
Sbjct: 462 LESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAA 521
Query: 210 QRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEE--------KLQEEQRKHS 261
QL+V Q + + K+ + + ++ +K+YS +E K +EE+
Sbjct: 522 SSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDL 581
Query: 262 AEKEALLEETNSFLKAIE------EANKKMQAAEISLEEKDQRIGELDRLIERME---KE 312
+ +L+ L+AIE + N+ + +L +++ +I EL + +ER++ K+
Sbjct: 582 LSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKD 641
Query: 313 RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLD-DMVHCQQKKVKQMV 371
++ L++ E E Y+ LE A+ R++ + L ++ H + + K +
Sbjct: 642 MKAIEDDLMKTEDE------------YETLERRYANERDKAQFLSKELEHVKMELAKYKL 689
Query: 372 EENNEL---QSRLDYLTETQAKTEVETREI 398
E E Q L E +AK+ +RE+
Sbjct: 690 AEKTETSHEQWLFKRLQEEEAKSGHLSREV 719
Score = 45.8 bits (107), Expect = 8e-05
Identities = 64/299 (21%), Positives = 125/299 (41%), Gaps = 55/299 (18%)
Query: 93 STSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQT 152
++SQL+ E N + V L + KR ++ +K+ +T+E ++ L+N ++
Sbjct: 521 ASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKE-------RDDLKNKLKA 573
Query: 153 Q----SSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRN-LQQTYEASMDKLR 207
+ + L R N + + L S LE KD ++N L Q S L
Sbjct: 574 EEEKGNDLLSRVNMLKNRLQS-------------LEAIE-KDFLKNKLNQDSGKSTTALH 619
Query: 208 EKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL 267
++ +++ E + LK+K++ + ++M+ E++ + +R+++ E+
Sbjct: 620 QENNKIKELSQEVERLKLKLKDMKAIEDDLMKT---------EDEYETLERRYANER--- 667
Query: 268 LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEM 327
++ K +E KM+ A+ L EK E Q + L+ E
Sbjct: 668 -DKAQFLSKELEHV--KMELAKYKLAEK-------------TETSHEQWLFKRLQEEEAK 711
Query: 328 SGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTE 386
SG L+ +++ E A+ + I HL QKK+ Q N +L ++ LT+
Sbjct: 712 SGHLSREVDALKEKIHEYMAT-EDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTK 769
Score = 38.1 bits (87), Expect = 0.016
Identities = 43/178 (24%), Positives = 93/178 (52%), Gaps = 29/178 (16%)
Query: 220 NQLLKMKVESSQEANAEVMREM--TKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKA 277
N+L K+ VE +E+ ++ ++ +K Q +L+EE+RKH + +E+++ F+
Sbjct: 141 NELDKV-VEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKH----KEYMEKSDEFICL 195
Query: 278 IE---EANKKMQAAEI-SLEEKDQRIGELDRLIERMEKERHQLQ---LQLLEHETEMSGE 330
+E E KK+ EI S EEK+Q E ++ + +++E +L+ L +++ + ++ +
Sbjct: 196 LEQECERLKKLIDQEIKSQEEKEQ---EKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQ 252
Query: 331 LTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQ 388
LT + Q+++E + + +E H + + V+E + +RL+ +TQ
Sbjct: 253 LT----LQRQKIQELTTNAKE--------THTKLALAEARVQEEEQKATRLEKELQTQ 298
Score = 28.9 bits (63), Expect = 9.6
Identities = 31/137 (22%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 266 ALLEETNSFL--KAIEEANKK--MQAAEISLEEK--DQRIGELDRLIERMEKERHQLQLQ 319
ALLE F+ K + EA ++ QA +E ++ + ELD+++E+ ++ ++ Q
Sbjct: 101 ALLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQ 160
Query: 320 LLEHETEMSGELTDSDKERYQQLEEASAS------LRERIRHLDDMVHCQQKKVKQMVEE 373
LL E + + ++E+ + E S L + L ++ +++K E+
Sbjct: 161 LLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQECERLKKLI---DQEIKSQEEK 217
Query: 374 NNELQSRLDYLTETQAK 390
E + R+ L E K
Sbjct: 218 EQEKEKRVTTLKEELTK 234
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 71.2 bits (173), Expect = 2e-12
Identities = 81/382 (21%), Positives = 158/382 (41%), Gaps = 41/382 (10%)
Query: 49 IERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVR 108
+E+ ++ + L E R L + + + + ++ Q+KE V + LKEE+ +K
Sbjct: 186 MEKSDEFICLLEQECER-LKKLIDQEIKSQEEKEQEKEKRV-----TTLKEELTKLKSFA 239
Query: 109 ATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALA 168
+ ++R+ RQKI++LT +H + E +Q + R + L
Sbjct: 240 LMVVDEQQRLTAQLTLQRQKIQELTTNAKETHTKLALAEARVQEEEQKATR---LEKELQ 296
Query: 169 SDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEA---SMDKLREKQRQLEVAQVENQLLKM 225
+ + + + + +N Q R LQQ A +D+L E R L A+ E Q +K
Sbjct: 297 TQTTKFHQDQDTIMAKLTNEDSQNRQLQQKLAALSRQIDELEETNRSLRKAEEELQDIKE 356
Query: 226 KVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKM 285
K+ + NA +M E+ EE RK + E EE + + NK++
Sbjct: 357 KISKGEYGNAGIMAEV-------------EELRKRVLDMEGKDEELIKMEEQCRDLNKRL 403
Query: 286 QAA-------EISLEEKDQRIGELDRLIERMEKERHQ-----LQLQLLEHETEMSGELTD 333
+ ++ +E+ +RI L++L + K + + L+ T+ + +
Sbjct: 404 ERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQELE 463
Query: 334 SDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRL----DYLTETQA 389
S K R ++LE + L + L + + + V+E + +L D L +
Sbjct: 464 SLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAASS 523
Query: 390 KTEVETREIGVGCDLLPSQTGR 411
+ +VE ++ + L +T R
Sbjct: 524 QLQVEQNKVTTVTEKLIEETKR 545
Score = 58.5 bits (140), Expect = 1e-08
Identities = 66/330 (20%), Positives = 141/330 (42%), Gaps = 39/330 (11%)
Query: 96 QLKEEMNYIKDVRATLEKVRKRMYG------DYDEMRQKIRQLTQELSVSHAQQEYLENH 149
+L+ E KD + +EK+ KR+ +++ +Q+ L L + L
Sbjct: 402 RLERETLQSKDFKLEVEKLSKRIMALEKLEDAFNKSKQECYSLKCNLEKERMTTKQLSQE 461
Query: 150 IQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREK 209
+++ + A+ S L L++ L + D+ + + + + + DKL+
Sbjct: 462 LESLKVRIKELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKLQAA 521
Query: 210 QRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEE--------KLQEEQRKHS 261
QL+V Q + + K+ + + ++ +K+YS +E K +EE+
Sbjct: 522 SSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKERDDLKNKLKAEEEKGNDL 581
Query: 262 AEKEALLEETNSFLKAIE------EANKKMQAAEISLEEKDQRIGELDRLIERME---KE 312
+ +L+ L+AIE + N+ + +L +++ +I EL + +ER++ K+
Sbjct: 582 LSRVNMLKNRLQSLEAIEKDFLKNKLNQDSGKSTTALHQENNKIKELSQEVERLKLKLKD 641
Query: 313 RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLD-DMVHCQQKKVKQMV 371
++ L++ E E Y+ LE A+ R++ + L ++ H + + K +
Sbjct: 642 MKAIEDDLMKTEDE------------YETLERRYANERDKAQFLSKELEHVKMELAKYKL 689
Query: 372 EENNEL---QSRLDYLTETQAKTEVETREI 398
E E Q L E +AK+ +RE+
Sbjct: 690 AEKTETSHEQWLFKRLQEEEAKSGHLSREV 719
Score = 45.8 bits (107), Expect = 8e-05
Identities = 64/299 (21%), Positives = 125/299 (41%), Gaps = 55/299 (18%)
Query: 93 STSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQT 152
++SQL+ E N + V L + KR ++ +K+ +T+E ++ L+N ++
Sbjct: 521 ASSQLQVEQNKVTTVTEKLIEETKRALKSKTDVEEKMYSVTKE-------RDDLKNKLKA 573
Query: 153 Q----SSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRN-LQQTYEASMDKLR 207
+ + L R N + + L S LE KD ++N L Q S L
Sbjct: 574 EEEKGNDLLSRVNMLKNRLQS-------------LEAIE-KDFLKNKLNQDSGKSTTALH 619
Query: 208 EKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL 267
++ +++ E + LK+K++ + ++M+ E++ + +R+++ E+
Sbjct: 620 QENNKIKELSQEVERLKLKLKDMKAIEDDLMKT---------EDEYETLERRYANER--- 667
Query: 268 LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEM 327
++ K +E KM+ A+ L EK E Q + L+ E
Sbjct: 668 -DKAQFLSKELEHV--KMELAKYKLAEK-------------TETSHEQWLFKRLQEEEAK 711
Query: 328 SGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTE 386
SG L+ +++ E A+ + I HL QKK+ Q N +L ++ LT+
Sbjct: 712 SGHLSREVDALKEKIHEYMAT-EDLICHLQGDHSVLQKKLNQQENRNRDLGREIENLTK 769
Score = 38.1 bits (87), Expect = 0.016
Identities = 43/178 (24%), Positives = 93/178 (52%), Gaps = 29/178 (16%)
Query: 220 NQLLKMKVESSQEANAEVMREM--TKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKA 277
N+L K+ VE +E+ ++ ++ +K Q +L+EE+RKH + +E+++ F+
Sbjct: 141 NELDKV-VEKHKESYRRILGQLLVAEKSRRQTILELEEEKRKH----KEYMEKSDEFICL 195
Query: 278 IE---EANKKMQAAEI-SLEEKDQRIGELDRLIERMEKERHQLQ---LQLLEHETEMSGE 330
+E E KK+ EI S EEK+Q E ++ + +++E +L+ L +++ + ++ +
Sbjct: 196 LEQECERLKKLIDQEIKSQEEKEQ---EKEKRVTTLKEELTKLKSFALMVVDEQQRLTAQ 252
Query: 331 LTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQ 388
LT + Q+++E + + +E H + + V+E + +RL+ +TQ
Sbjct: 253 LT----LQRQKIQELTTNAKE--------THTKLALAEARVQEEEQKATRLEKELQTQ 298
Score = 28.9 bits (63), Expect = 9.6
Identities = 31/137 (22%), Positives = 62/137 (45%), Gaps = 15/137 (10%)
Query: 266 ALLEETNSFL--KAIEEANKK--MQAAEISLEEK--DQRIGELDRLIERMEKERHQLQLQ 319
ALLE F+ K + EA ++ QA +E ++ + ELD+++E+ ++ ++ Q
Sbjct: 101 ALLEAQYGFVTPKKVLEALQRDAFQAKSTPWQEDIYEKPMNELDKVVEKHKESYRRILGQ 160
Query: 320 LLEHETEMSGELTDSDKERYQQLEEASAS------LRERIRHLDDMVHCQQKKVKQMVEE 373
LL E + + ++E+ + E S L + L ++ +++K E+
Sbjct: 161 LLVAEKSRRQTILELEEEKRKHKEYMEKSDEFICLLEQECERLKKLI---DQEIKSQEEK 217
Query: 374 NNELQSRLDYLTETQAK 390
E + R+ L E K
Sbjct: 218 EQEKEKRVTTLKEELTK 234
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 70.9 bits (172), Expect = 2e-12
Identities = 71/279 (25%), Positives = 131/279 (46%), Gaps = 13/279 (4%)
Query: 76 VRRSDQNQQKEMVVYGWSTSQ-LKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQ 134
V R +Q + +E+ + Q L+ + + + LE+ + + ++++++ QL++
Sbjct: 782 VAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSR 841
Query: 135 ELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRN 194
+LS + E Q Q AL+R ALA + GL LV E + ++
Sbjct: 842 QLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAVQLVAAEREGRTLSEEATR 901
Query: 195 LQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQ 254
L+ EA L E QRQL AQ+E + + ++E+ +A +T +L + +++
Sbjct: 902 LRLEKEALEGSLFEVQRQL--AQLEAR--REQLEAEGQALLLAKETLTGEL-AGLRQQII 956
Query: 255 EEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI-GELDRLIERMEKER 313
Q K S +KE + ++ ++A EA ++ + EE QR+ E + +E ER
Sbjct: 957 ATQEKASLDKELMAQK---LVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAER 1013
Query: 314 HQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRER 352
QLQ QL + E+ L + E+ + EE +A +ER
Sbjct: 1014 AQLQSQLQREQEELLARL---EAEKEELSEEIAALQQER 1049
Score = 65.1 bits (157), Expect = 1e-10
Identities = 65/286 (22%), Positives = 121/286 (42%), Gaps = 22/286 (7%)
Query: 75 VVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQ 134
++ R N + V +L++E ++ + L + R R+ + ++ Q ++ +
Sbjct: 600 LLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRR 659
Query: 135 ELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNI---KDQ 191
EL SH Q E LE S LA + + +++ L TL+ + K +
Sbjct: 660 ELERSHRQLEQLEGK--------------RSVLAKELVEVREALSRATLQRDMLQAEKAE 705
Query: 192 IRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEE 251
+ EA +L +L + Q K+ + E+ A+ ++ + + EE
Sbjct: 706 VAEALTKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEE 765
Query: 252 KLQEEQRKHSAEKEALL--EETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERM 309
K + R+ AE+EA + EE + E Q E SL +Q L++ + +
Sbjct: 766 KSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTL 825
Query: 310 EKERHQLQLQLLEHETEMSG---ELTDSDKERYQQLEEASASLRER 352
ER QLQ QL + ++SG EL + +E +Q+E + RE+
Sbjct: 826 RHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREK 871
Score = 57.8 bits (138), Expect = 2e-08
Identities = 51/291 (17%), Positives = 129/291 (44%), Gaps = 10/291 (3%)
Query: 95 SQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQS 154
++++E ++D L + + + R K L + L+ ++ L+ +
Sbjct: 1715 AKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAAR 1774
Query: 155 SALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLE 214
AL +S+L L+ + D+ L+ + Q++ L++ + ++
Sbjct: 1775 QALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQ 1834
Query: 215 VAQVENQLLKMKVESSQEANAEV---MREMTKKLYSQYEEKLQEEQRKHSAEKEALLEET 271
Q E +LL+ ++ S Q A A++ RE+ + ++++ + E+E L
Sbjct: 1835 KLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHE 1894
Query: 272 NSFLKAIEEA--NKKMQAAEISLEEKDQRIGELDRLIERMEKERH--QLQLQLLEHETEM 327
++ + E+ ++ + AE+ L E ++I +L+ + +E+ QL++ + + E+
Sbjct: 1895 DTVRLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLEL 1954
Query: 328 SGE---LTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENN 375
E L + + + LE + R+R+R L++ V + +++Q + ++
Sbjct: 1955 QQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQLQQELRRSS 2005
Score = 52.4 bits (124), Expect = 8e-07
Identities = 75/361 (20%), Positives = 153/361 (42%), Gaps = 55/361 (15%)
Query: 105 KDVRATLEKVRKRMYGDYDEMRQKIRQLTQELS--VSHAQQEYLENHIQTQSS---ALDR 159
+++ A +++ ++ + +E+ ++ +ELS ++ QQE E + +S AL
Sbjct: 1007 RELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQQALSL 1066
Query: 160 FNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQL------ 213
+ +AL+ +G + +L ++LE K ++ Q+ ++++ L + R L
Sbjct: 1067 KESEKTALSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREE 1126
Query: 214 -------EVAQVENQLLKM-KVESSQEANAEVMREMTKKLYS----------QYEEKLQE 255
EV +++ Q + K S AE +R + L + + KL+E
Sbjct: 1127 AAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRE 1186
Query: 256 EQR-----------------KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQR 298
Q + + E+EAL A+++A + + +++ E+K+Q+
Sbjct: 1187 SQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQK 1246
Query: 299 IGELDRLIERMEKERHQLQLQLLEHE---TEMSGELTDSDKERYQQLEEASASLRERIRH 355
+ L+ + KE +L+ L E E E EL + + + + L+ + L +
Sbjct: 1247 LALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQEL-RRQMKMLDSENTRLGRELAE 1305
Query: 356 LDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTG--RTR 413
L + ++ K+ E L+ R L + +A EV +E+ V L Q G RTR
Sbjct: 1306 LQGRLALGERAEKESRRETLGLRQR---LLKGEASLEVMRQELQVAQRKLQEQEGEFRTR 1362
Query: 414 E 414
E
Sbjct: 1363 E 1363
Score = 50.8 bits (120), Expect = 2e-06
Identities = 70/343 (20%), Positives = 139/343 (40%), Gaps = 40/343 (11%)
Query: 58 LSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKR 117
++ E R+ G + GV Q E+ + S + + E D ATLE+ +
Sbjct: 1560 VAESEEARRSVDGRLSGV--------QAELALQEESVRRSERERRATLDQVATLERSLQA 1611
Query: 118 MYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKT 177
+ ++KI ++ + + L+ + S + +L + +
Sbjct: 1612 TESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLG 1671
Query: 178 LVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEV 237
L D + ++D++ +LQ+ + + +++ QL V ++ L KVE S+ A +
Sbjct: 1672 LSDREAQAQALQDRVDSLQR--QVADSEVKAGTLQLTVERLNGAL--AKVEESEGALRDK 1727
Query: 238 MREMTKKLYSQYEEKLQEEQRKHSAEKEAL--LEETNSFLKAIEEANKKMQAAEISLEEK 295
+R +T+ L +Q L + K+ ++AL E L+ +++ AA +L E
Sbjct: 1728 VRGLTEAL-AQSSASLNSTRDKNLHLQKALTACEHDRQVLQ------ERLDAARQALSEA 1780
Query: 296 DQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRH 355
++ L ++ + E L+LQ +E E ++ LRE +R
Sbjct: 1781 RKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQ-------------------QLREVLRQ 1821
Query: 356 LDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREI 398
+ V+++ +E LQ RL L A+ E E RE+
Sbjct: 1822 RQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREV 1864
Score = 50.4 bits (119), Expect = 3e-06
Identities = 54/230 (23%), Positives = 111/230 (48%), Gaps = 19/230 (8%)
Query: 168 ASDSIG-LQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMK 226
+ D +G L+K L D E +++Q++ L+ + +M + QR+++ + N+LL +
Sbjct: 545 SQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLS-R 603
Query: 227 VESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQ 286
+S+ + +V ++ ++L Q EKLQ Q + +++ L EE ++ ++++
Sbjct: 604 EKSNLAHSLQVAQQQAEEL-RQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELE 662
Query: 287 AAEISLEEKDQRIGELDR-LIE-RMEKERHQLQLQLLEHE-TEMSGELTDSDKERYQ--- 340
+ LE+ + + L + L+E R R LQ +L+ E E++ LT ++ R +
Sbjct: 663 RSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELEL 722
Query: 341 ---QLEEASASLRERIRHLDDMVHC-------QQKKVKQMVEENNELQSR 380
+L ASL++ + L + + V Q+ EE + LQ R
Sbjct: 723 SMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGR 772
Score = 49.7 bits (117), Expect = 5e-06
Identities = 63/273 (23%), Positives = 118/273 (43%), Gaps = 31/273 (11%)
Query: 121 DYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDR----FNAMNSALASDSIGLQK 176
D + +R +R+ QEL AQ+E + ++TQ+SAL+R A + S + LQK
Sbjct: 1503 DPEAVRGALREFLQELR--SAQRE--RDELRTQTSALNRQLAEMEAERDSATSRARQLQK 1558
Query: 177 TLVDVTLENSNIKDQIRNLQQTYEASMDKLR--EKQRQLEVAQVENQLLKMKVESSQEAN 234
+ + ++ ++ +Q + +R E++R+ + QV +E S +A
Sbjct: 1559 AVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVAT------LERSLQAT 1612
Query: 235 AEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEE 294
+R +K+ K++ + K +K L E L A E K++ SLE
Sbjct: 1613 ESELRASQEKI-----SKMKANETKLEGDKRRLKE----VLDASESRTVKLELQRRSLEG 1663
Query: 295 KDQR--IGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQ----QLEEASAS 348
+ QR +G DR + + LQ ++E+ ER ++EE+ +
Sbjct: 1664 ELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGA 1723
Query: 349 LRERIRHLDDMVHCQQKKVKQMVEENNELQSRL 381
LR+++R L + + + ++N LQ L
Sbjct: 1724 LRDKVRGLTEALAQSSASLNSTRDKNLHLQKAL 1756
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/296 (21%), Positives = 123/296 (41%), Gaps = 42/296 (14%)
Query: 106 DVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHA-------QQEYLENHIQTQSSALD 158
++RA+ EK+ K M + ++ R+L + L S + Q+ LE +Q L
Sbjct: 1615 ELRASQEKISK-MKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLS 1673
Query: 159 RFNAMNSALASDSIGLQKTLVD---------VTLENSN------------IKDQIRNLQQ 197
A AL LQ+ + D +T+E N ++D++R L +
Sbjct: 1674 DREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTE 1733
Query: 198 TY---EASMDKLREK----QRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYE 250
AS++ R+K Q+ L + + Q+L+ +++++++A +E +K S
Sbjct: 1734 ALAQSSASLNSTRDKNLHLQKALTACEHDRQVLQERLDAARQALSEA-----RKQSSSLG 1788
Query: 251 EKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERME 310
E++Q R A+ E E L+ + E ++ Q E + Q++ + RL++
Sbjct: 1789 EQVQT-LRGEVADLELQRVEAEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERL 1847
Query: 311 KERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKK 366
+ QL + E+ +K+R RE++R +D V +K
Sbjct: 1848 GSLQRALAQLEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEK 1903
Score = 47.8 bits (112), Expect = 2e-05
Identities = 77/395 (19%), Positives = 157/395 (39%), Gaps = 56/395 (14%)
Query: 46 EKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIK 105
EK + +++ DL + + ++ + + V R QN +K+ V L E++ ++
Sbjct: 378 EKDLAQQQMQSDLDKADLSARVTE-LGLAVKRLEKQNLEKDQV-----NKDLTEKLEALE 431
Query: 106 DVRATLEKVRKRMYGDYDEMRQKIRQLTQEL---SVSHAQQEYLENHIQTQSSALDRFNA 162
+R L++ D + ++Q +R L Q + S S Q E + +L +
Sbjct: 432 SLR--LQEQAALETEDGEGLQQTLRDLAQAVLSDSESGVQLSGSERTADASNGSLRGLSG 489
Query: 163 MN--------------------SALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEAS 202
S SDS L L+ L + Q+++++ YEAS
Sbjct: 490 QRTPSPPRRSSPGRGRSPRRGPSPACSDSSTL--ALIHSALHKRQL--QVQDMRGRYEAS 545
Query: 203 MDKLREKQRQLEVAQVEN-------QLLKMKVESSQEANAEVMREMTK-----KLYSQYE 250
D L ++QL ++ E Q L+ K + + +A+ + RE+ + +L S+ +
Sbjct: 546 QDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREK 605
Query: 251 EKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQ-------RIGELD 303
L + + E L +E A EE ++ E E+ Q +
Sbjct: 606 SNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSH 665
Query: 304 RLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQ 363
R +E++E +R L +L+E +S D + ++ E A A + ++ +
Sbjct: 666 RQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEALTKAEAGRVE--LELS 723
Query: 364 QKKVKQMVEENNELQSRLDYLTETQAKTEVETREI 398
K++ + S+L L E+ A+ +++ +
Sbjct: 724 MTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRL 758
Score = 44.7 bits (104), Expect = 2e-04
Identities = 54/221 (24%), Positives = 95/221 (42%), Gaps = 18/221 (8%)
Query: 193 RNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQE--ANAEVMREMTKKLYSQYE 250
RNL Q + E L + Q ENQLL+ ++ ++ A + R+ Y+
Sbjct: 57 RNLSQPESPVLLPATEMASLLSL-QEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVS 115
Query: 251 EKLQEEQRKHSAEKEA-----LLEETNSFLKAIEEAN----KKMQAAEISLEEKDQRIGE 301
E+L++ R E E L+ ++ + ++E +K+QA + + + Q +
Sbjct: 116 ERLEQALRLEPGELETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQR 175
Query: 302 LDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRE---RIRHLDD 358
L I + +K +L+ QLLE E+ + D E Q LE A L E R L
Sbjct: 176 LQGKILQYKKRCSELEQQLLERSGELEQQRL-RDTEHSQDLESALIRLEEEQQRSASLAQ 234
Query: 359 MVHCQQKKVKQMVEENNELQSRLDYLTE--TQAKTEVETRE 397
+ ++++ Q N L + +T T+ + E+E RE
Sbjct: 235 VNAMLREQLDQAGSANQALSEDIRKVTNDWTRCRKELEHRE 275
Score = 37.7 bits (86), Expect = 0.021
Identities = 38/192 (19%), Positives = 88/192 (45%), Gaps = 16/192 (8%)
Query: 81 QNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQEL---- 136
Q Q+ E + +L++E +++ +L++ ++ + E+ + +L ++
Sbjct: 1821 QRQEGEAAALN-TVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR 1879
Query: 137 -SVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNL 195
++ ++E L +H T R +A L G + L + + ++ Q+ L
Sbjct: 1880 RTLDKVEREKLRSHEDTV-----RLSAEKGRLDRTLTGAELELAEAQRQIQQLEAQVVVL 1934
Query: 196 QQTYEASMDKLREKQRQLEVAQVENQL--LKMKVESSQEANAEVMREMTKKLYSQ---YE 250
+Q++ + ++ +Q+QLE+ Q +L + + E + EA R+ + L Q +
Sbjct: 1935 EQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTERTLEARERAHRQRVRGLEEQVSTLK 1994
Query: 251 EKLQEEQRKHSA 262
+LQ+E R+ SA
Sbjct: 1995 GQLQQELRRSSA 2006
Score = 36.2 bits (82), Expect = 0.060
Identities = 45/215 (20%), Positives = 84/215 (39%), Gaps = 32/215 (14%)
Query: 232 EANAEVMREMTKKLYSQYEEK---------LQEEQRKHSAEKEALLEETNSFLKAIEEAN 282
EA +RE ++L S E+ L + + AE+++ KA+ E+
Sbjct: 1505 EAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESE 1564
Query: 283 KKMQA---------AEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGE--- 330
+ ++ AE++L+E+ R E +R + + LQ E E S E
Sbjct: 1565 EARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKIS 1624
Query: 331 -------LTDSDKERYQQLEEASAS----LRERIRHLDDMVHCQQKKVKQMVEENNELQS 379
+ DK R +++ +AS S L + R L+ + + + + LQ
Sbjct: 1625 KMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQD 1684
Query: 380 RLDYLTETQAKTEVETREIGVGCDLLPSQTGRTRE 414
R+D L A +EV+ + + + L + E
Sbjct: 1685 RVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEE 1719
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 70.9 bits (172), Expect = 2e-12
Identities = 96/419 (22%), Positives = 166/419 (39%), Gaps = 53/419 (12%)
Query: 12 SGGAA--RTPGAPSRRANVCRLRLTVPPESPVPEQCEKKIERKEQLLDLSNGEPTRKLPQ 69
+GGA+ + G R A + RLR + + E + RK+ GE L
Sbjct: 1202 AGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSL-- 1259
Query: 70 GVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKI 129
+R Q +KE L + + +A+ EK+ + E + K+
Sbjct: 1260 -------QRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKV 1312
Query: 130 RQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTL------ 183
+L ++L+ + Q+ +QT+S L R L S + K L +L
Sbjct: 1313 EELQRQLADASTQR----GRLQTESGELSRLLEEKECLIS-QLSRGKALAAQSLEELRRQ 1367
Query: 184 --ENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKV-------ESSQEAN 234
E S K + + Q D LRE+ + AQ E Q L K S EA+
Sbjct: 1368 LEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEAD 1427
Query: 235 A----EVMREMTKKLYSQYEE-------------KLQEEQRKHSAEKEALLEETNSFLKA 277
A E + E KKL + +E L++ + + E E + E A
Sbjct: 1428 AIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSA 1487
Query: 278 IEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQL--LEHETEMSGELTDSD 335
+KK + E +LEE+ ++ E+ R +E ++E L +L L H E + E ++
Sbjct: 1488 AAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETL 1547
Query: 336 KERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVE 394
K + L+E + L +++ + +K K + E +E+Q+ L+ E + E+E
Sbjct: 1548 KRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALE---EAEGALELE 1603
Score = 70.5 bits (171), Expect = 3e-12
Identities = 76/336 (22%), Positives = 146/336 (43%), Gaps = 36/336 (10%)
Query: 97 LKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIR----QLTQELSVSHAQQEYLENHIQT 152
L+E+ + +A L+++ + + + R K Q T+EL + ++ L +Q
Sbjct: 1392 LREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEA---KKKLALRLQE 1448
Query: 153 QSSALDRFNAMNSALASDSIGLQKTLVDVTLENSN-------IKDQIRNLQQTYEASMDK 205
++ NA S+L + LQ DVTLE + + R+L++ E +
Sbjct: 1449 AEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQ 1508
Query: 206 LREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKE 265
E QR+LE AQ E++ L ++ + + E + + E L+ E + E
Sbjct: 1509 EEEMQRELEAAQRESRGLGTELFRLRHGHEEALEAL---------ETLKRENKNLQEEIS 1559
Query: 266 ALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHET 325
L ++ + K+I+E K +A E E + E + +E E + ++QL+L + +
Sbjct: 1560 DLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKA 1619
Query: 326 EMSGELTDSDKE-------RYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQ 378
E+ +L + D+E + +E ASL R ++ + + K+M + N+L+
Sbjct: 1620 EVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLK----KKMEGDLNDLE 1675
Query: 379 SRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTRE 414
+L + T + + TR + L Q GR E
Sbjct: 1676 LQLGHATRQATEAQAATRL--MQAQLKEEQAGRDEE 1709
Score = 53.1 bits (126), Expect = 5e-07
Identities = 67/328 (20%), Positives = 149/328 (45%), Gaps = 29/328 (8%)
Query: 95 SQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQS 154
++LK++++ +K A EK ++ + +++ L + ++ +++ L+ Q
Sbjct: 997 TELKKDIDDLKLTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQAL 1056
Query: 155 SALDRFNAMNSALASDSIGLQKTLVDVT----------LENSNIKDQIR-NLQQTYEASM 203
L SAL + L++ + D+ ++ K ++ +L+ T E+
Sbjct: 1057 GDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVA 1116
Query: 204 DKLREKQR---QLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKH 260
D ++KQ+ +L+ E L ++VE Q A++ +++ K+L ++ EE L+EE
Sbjct: 1117 DAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKI-KELQARAEE-LEEELEAE 1174
Query: 261 SAEKEALLEETNSFLKAIEEANKKM-QAAEISLEEKD---QRIGELDRLIERMEKE--RH 314
A + + ++ + +EE ++++ +A S +++ +R EL RL +E+ RH
Sbjct: 1175 RAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRH 1234
Query: 315 QLQLQLLEHETEMS----GELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQM 370
+ + L + GE DS + Q+LE+ + LR + DD+ + +
Sbjct: 1235 EATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEV---DDLAANVETLTRAK 1291
Query: 371 VEENNELQSRLDYLTETQAKTEVETREI 398
++ D L+E + K E R++
Sbjct: 1292 ASAEKLCRTYEDQLSEAKIKVEELQRQL 1319
Score = 52.4 bits (124), Expect = 8e-07
Identities = 55/321 (17%), Positives = 136/321 (42%), Gaps = 32/321 (9%)
Query: 113 KVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSI 172
+++K+M GD +++ ++ T++ + + A ++ ++ + + D + + L +
Sbjct: 1662 RLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQ 1721
Query: 173 GLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLL---KMKVES 229
L++ + E ++ + +++ + +L E +L + +N L K K+E+
Sbjct: 1722 ALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEA 1781
Query: 230 S---------------QEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSF 274
+EA + + +T E K +++ H + LE+T
Sbjct: 1782 DLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRE 1841
Query: 275 LKA-IEEANK-KMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELT 332
L+A +EEA + ++ + +++ + ++ EL+ ++ +K+ + + +HE +
Sbjct: 1842 LQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRV----- 1896
Query: 333 DSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTE 392
KE Q EE R+ + + D+V Q KVK + E + + + K +
Sbjct: 1897 ---KELAYQAEED----RKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQ 1949
Query: 393 VETREIGVGCDLLPSQTGRTR 413
E + D+ +Q + R
Sbjct: 1950 HELDDAEERADMAETQANKLR 1970
Score = 48.1 bits (113), Expect = 2e-05
Identities = 58/274 (21%), Positives = 115/274 (41%), Gaps = 17/274 (6%)
Query: 125 MRQKIRQLTQELSVSHAQ-QEYLENHIQTQSSALD---RFNAMNSALASDSIGLQKTLVD 180
+R ++R L L+ + A+ QE E H+ D + A LA +
Sbjct: 901 LRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKS 960
Query: 181 VTLENSNIKDQIRNLQQTYEASMD------KLREKQRQLEVAQVENQLLKMKVESSQEAN 234
+K+ L+ E + D KL ++ +L+ + +L K E ++A
Sbjct: 961 KVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQAT 1020
Query: 235 AEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEE 294
++ +T+++ + L E + + EK+AL E L ++ ++ A +
Sbjct: 1021 ENKVKNLTEEMAA-----LDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLR 1075
Query: 295 KDQRIGELDRLIERMEKERHQLQL--QLLEHETEMSGELTDSDKERYQQLEEASASLRER 352
+Q++ +L+ +E+ +K R + + LE + +++ E + QQLEE
Sbjct: 1076 LEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSE 1135
Query: 353 IRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTE 386
+ L V +Q QM ++ ELQ+R + L E
Sbjct: 1136 LSQLSLRVEDEQLLGAQMQKKIKELQARAEELEE 1169
Score = 47.8 bits (112), Expect = 2e-05
Identities = 56/280 (20%), Positives = 117/280 (41%), Gaps = 50/280 (17%)
Query: 85 KEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQE 144
K V +L E + ++V A L R+++ + E+++ I L L+ + +++
Sbjct: 959 KSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLTLAKAEKEKQ 1018
Query: 145 YLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMD 204
EN ++ L + L +++ +T E + LQ+ ++ ++
Sbjct: 1019 ATENKVKN--------------LTEEMAALDESVARLTKEK-------KALQEAHQQALG 1057
Query: 205 KLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK 264
L+ ++ ++ L+ +VE + E E KKL ++ E+ K E
Sbjct: 1058 DLQAEEDRVSALTKAKLRLEQQVE-----DLECSLEQEKKL------RMDTERAKRKLEG 1106
Query: 265 EALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIE-------RMEKERHQLQ 317
+ L + +++ +A + Q E L++KD + +L +E +M+K+ +LQ
Sbjct: 1107 DLKLTQ-----ESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQ 1161
Query: 318 LQLLEHETEMSGE------LTDSDKERYQQLEEASASLRE 351
+ E E E+ E + E ++LEE S L E
Sbjct: 1162 ARAEELEEELEAERAARARVEKQRAEAARELEELSERLEE 1201
Score = 44.7 bits (104), Expect = 2e-04
Identities = 78/348 (22%), Positives = 141/348 (40%), Gaps = 69/348 (19%)
Query: 84 QKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQL----------- 132
QK++ +L+EE+ + RA +EK R + +E+ +++ +
Sbjct: 1154 QKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGC 1213
Query: 133 -TQELSVSHAQQEYLENHIQTQS--SALDRFNAMNSALASDSI-GLQKTLVDVTLENSNI 188
+E + ++E E ++ ++ +AL R A +A + + LQ+ + E S +
Sbjct: 1214 RKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSEL 1273
Query: 189 KDQIRNLQQTYE------ASMDKL-REKQRQLEVAQVENQLLKMKVESSQEANAEVMREM 241
+ ++ +L E AS +KL R + QL A K+KVE Q A+
Sbjct: 1274 RMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEA-------KIKVEELQRQLADA---- 1322
Query: 242 TKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGE 301
S +LQ E S E LLEE + + K AA+ SLEE +++ E
Sbjct: 1323 -----STQRGRLQTE----SGELSRLLEEKECLISQLSRG--KALAAQ-SLEELRRQLEE 1370
Query: 302 LDR----LIERMEKERHQLQLQLLEHETEMSGE------LTDSDKE-------------- 337
+ L ++ RH L +HE E + L+ ++ E
Sbjct: 1371 ESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQ 1430
Query: 338 RYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLT 385
R ++LEEA L R++ ++ V K + + LQ+ + +T
Sbjct: 1431 RTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVT 1478
Score = 33.5 bits (75), Expect = 0.39
Identities = 30/170 (17%), Positives = 71/170 (41%), Gaps = 6/170 (3%)
Query: 77 RRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQ-E 135
RR + + K+ + + + EE+ +D A LE+++K + E++ ++ + Q
Sbjct: 1797 RREAEEKAKKAIT---DAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAA 1853
Query: 136 LSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNL 195
L Q + LE ++ + LD ++ ++ + ++ + + + +
Sbjct: 1854 LRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARM 1913
Query: 196 QQTYEASMDKLREKQRQLEVA--QVENQLLKMKVESSQEANAEVMREMTK 243
Q + K++ +RQ E A Q L K + + +AE +M +
Sbjct: 1914 QDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAE 1963
Score = 33.1 bits (74), Expect = 0.51
Identities = 37/153 (24%), Positives = 67/153 (43%), Gaps = 18/153 (11%)
Query: 244 KLYSQYEEKLQEEQRKHS-AEKEALLEETNSFLKAIEEANKKMQAAEISL-EEKDQRIGE 301
KL+ + + L+ Q + A A L L A E ++++ +S+ +EK+ +
Sbjct: 880 KLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQ 939
Query: 302 LDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVH 361
L + + + L L++ + ++ G++ + ER + EE +A L R R L+D
Sbjct: 940 LQAEQDNLADAEERCHL-LIKSKVQLEGKVKELS-ERLEDEEEVNADLAARRRKLED--- 994
Query: 362 CQQKKVKQMVEENNELQSRLDYLTETQAKTEVE 394
E EL+ +D L T AK E E
Sbjct: 995 -----------ECTELKKDIDDLKLTLAKAEKE 1016
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 70.5 bits (171), Expect = 3e-12
Identities = 68/323 (21%), Positives = 149/323 (46%), Gaps = 21/323 (6%)
Query: 76 VRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQE 135
+R ++ +K+ +L+E+ +++ + + KR+ E+R++ ++L ++
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQ 340
Query: 136 LSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNL 195
+ Q+E ++ + ++ + L + + + ++DQ +
Sbjct: 341 KELRE-QEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 399
Query: 196 QQTYEASMDKLREKQRQL-EVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQ 254
+ E +LREK+ ++ E ++ Q+ KM+ E M+E KK Q EEK+Q
Sbjct: 400 WEQDE----RLREKEERMREQEKMWEQVEKMREEKK-------MQEQEKKTRDQ-EEKMQ 447
Query: 255 EEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERH 314
EE+R EK+ EE + + E +KMQ E ++ E++++ + RL E+ EK
Sbjct: 448 EEERIREREKKMREEE-----ETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE 502
Query: 315 QLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEEN 374
Q ++Q E + E +E + Q E +E++R +D + Q++K++ ++
Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQ--EKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 375 NELQSRLDYLTETQAKTEVETRE 397
+ + R++ T+ Q K + E
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEE 583
Score = 57.0 bits (136), Expect = 3e-08
Identities = 62/264 (23%), Positives = 115/264 (43%), Gaps = 16/264 (6%)
Query: 144 EYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASM 203
E L S L R N L + LQ+ L E S I+ ++ L++ E +
Sbjct: 200 EELTKERDALSLELYRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKELKRKLERAK 259
Query: 204 DKLREKQR---QLEVAQVENQLLKM-----KVESSQEANAEVMREMTKKLYSQYEEKLQE 255
L + Q Q E+ + E +L + K E E +RE K+ Q E+ ++
Sbjct: 260 FLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ 319
Query: 256 EQRKHSAEKEALLEETN-SFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERH 314
E+R EKE +E K + E ++MQ E + E+++++ E + + R E+
Sbjct: 320 EKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLW 379
Query: 315 QLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQK--KVKQMVE 372
+ + Q+ E E +M + +ER + +E ER+R + M +K + K+M E
Sbjct: 380 EQEKQMREQEQKMRDQ-----EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQE 434
Query: 373 ENNELQSRLDYLTETQAKTEVETR 396
+ + + + + + E + E E +
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKK 458
Score = 57.0 bits (136), Expect = 3e-08
Identities = 56/322 (17%), Positives = 141/322 (43%), Gaps = 28/322 (8%)
Query: 78 RSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELS 137
R + Q +E W E+ +++ + + +R++ +MR++ +++ +
Sbjct: 344 REQEEQMQEQEEKMW------EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEE 397
Query: 138 VSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQ 197
Q E L + + + + Q+ E +++IR ++
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK 457
Query: 198 TYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEA---------NAEVMREMTKKLYSQ 248
+ +RE++ +++ Q EN + + E Q+ E M+E +K++ Q
Sbjct: 458 KMREEEETMREQEEKMQ-KQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQ 516
Query: 249 YEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIER 308
EEK+++++ EK+ +E + E +M E + +++Q++ + + ER
Sbjct: 517 -EEKIRDQEEMWGQEKKMWRQEK------MREQEDQMWEQEEKMRDQEQKMWDQE---ER 566
Query: 309 MEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVK 368
MEK+ + + + + E +M E + +ER +++ E +RE+ + + Q++ +
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREE--ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEE 624
Query: 369 QMVEENNELQSRLDYLTETQAK 390
+M E+ ++Q + + + E + K
Sbjct: 625 KMWEQEEKMQEQEEKMWEQEEK 646
Score = 56.6 bits (135), Expect = 4e-08
Identities = 61/309 (19%), Positives = 134/309 (43%), Gaps = 32/309 (10%)
Query: 83 QQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQ 142
Q+K+M W +++E+ + + + + ++M+ + M +K TQE
Sbjct: 529 QEKKM----WRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKK----TQEQEKKTWD 580
Query: 143 QEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEAS 202
QE + + + +Q+ + + + +Q +Q+ E
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ-EEK 639
Query: 203 MDKLREKQRQLEVAQVENQLLKMKVESSQE----ANAEVMREMTKKLYSQYE-EKLQEEQ 257
M + EK + E E Q L + E E E M+E +K++ Q + EK +EQ
Sbjct: 640 MWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQ 699
Query: 258 RKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQ 317
K + ++E + EE +++ E KKM+ E + E+++++ E + ++ E+E + +
Sbjct: 700 EKKTWDQEKMREE-----ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQE 754
Query: 318 LQLLEHETEM---------SGELTDSDK----ERYQQLEEASASLRERIRHLDDMVHCQQ 364
++ E E +M +L + +K E+ + EE E++R ++ + Q+
Sbjct: 755 EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQE 814
Query: 365 KKVKQMVEE 373
+K++ E+
Sbjct: 815 EKMRGQEEK 823
Score = 56.2 bits (134), Expect = 6e-08
Identities = 45/195 (23%), Positives = 101/195 (51%), Gaps = 11/195 (5%)
Query: 204 DKLREKQRQLE---VAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKH 260
+K+RE++R E + E ++++ + E QE E M+E +K++ Q EEK+QE++ K
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQE-EKMQEQEEKMWEQ-EEKMQEQEEKM 640
Query: 261 SAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLI---ERMEKERHQLQ 317
++E + E+ + +K + E ++ +++ E + I E+MEK+ + +
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQE 700
Query: 318 LQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNEL 377
+ + E +M E +S +ER +++ E +RE+ + + Q++ ++M E+ ++
Sbjct: 701 KKTWDQE-KMREE--ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKM 757
Query: 378 QSRLDYLTETQAKTE 392
+ + + E Q E
Sbjct: 758 WEQEEKMWEQQRLPE 772
Score = 48.5 bits (114), Expect = 1e-05
Identities = 54/334 (16%), Positives = 144/334 (43%), Gaps = 20/334 (5%)
Query: 46 EKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNYIK 105
E+++E+K Q + + K+ R ++ ++ ++E+ ++
Sbjct: 564 EERMEKKTQEQEKKTWDQEEKM----------REEERMREREKKMREEEEMMREQEEKMQ 613
Query: 106 DVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYL--ENHIQTQSSALDRFNAM 163
+ +++ ++M+ ++M+++ ++ ++ Q+E + + + Q L M
Sbjct: 614 EQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673
Query: 164 NSALA----SDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVE 219
+ I Q+ + T E +++ E SM + +K R+ E E
Sbjct: 674 QEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMRE--EESMREREKKMREEEEMMRE 731
Query: 220 NQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIE 279
+ + E + E M E +K++ Q EEK+ E+QR +++ E + I
Sbjct: 732 QEEKMQEQEEKMQEQEEEMWEQEEKMWEQ-EEKMWEQQRLPEQKEKLWEHEKMQEQEKIW 790
Query: 280 EANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERY 339
E +KM+ E + +++++ + + E++ + ++ E +M G+ + +
Sbjct: 791 EQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQ-EEKMWGQE 849
Query: 340 QQLEEASASLRERIRHLDDMVHCQQKKVKQMVEE 373
+++EE E++R ++ + Q++K+++ E+
Sbjct: 850 EKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
Score = 46.2 bits (108), Expect = 6e-05
Identities = 58/319 (18%), Positives = 138/319 (43%), Gaps = 38/319 (11%)
Query: 98 KEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSAL 157
+EE + +D R ++ R R + ++M +++ ++ +E + +++ + + Q
Sbjct: 395 QEERMWEQDERLREKEERMR---EQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEER 451
Query: 158 DRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQ 217
R +++ Q+ + EN +++ QQ +KL E+++ E +
Sbjct: 452 IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEE 511
Query: 218 --------------VENQLLKMKVESSQEANAEVMREMTKKLYSQ----------YEEKL 253
+ Q KM + + M E +K+ Q E+K
Sbjct: 512 KIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKT 571
Query: 254 QEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKER 313
QE+++K ++E + EE + + E KKM+ E + E+++++ E + ++ E++
Sbjct: 572 QEQEKKTWDQEEKMREE-----ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKM 626
Query: 314 HQLQLQLLEHETEMSGELTDSDKERYQQLEE--ASASLRERIRHLDDMVHCQQKKVKQMV 371
+ + ++ E E +M + +++ ++Q E+ L E+ L + Q+++ Q
Sbjct: 627 WEQEEKMQEQEEKM----WEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ 682
Query: 372 EENNELQSRLDYLTETQAK 390
EE Q +++ T+ Q K
Sbjct: 683 EEKIWEQEKMEKKTQEQEK 701
Score = 45.8 bits (107), Expect = 8e-05
Identities = 63/299 (21%), Positives = 115/299 (38%), Gaps = 39/299 (13%)
Query: 108 RATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRF------- 160
RA L++ +K + + +R++I + + Q+ LE + A +F
Sbjct: 76 RAQLKEEKKASHQHQEALRREIEAQDHTIRILTCQKTELETALYYSQDAARKFEDGNLGT 135
Query: 161 -NAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVE 219
++ N AL+ G V +L KD L ++ + E QR L
Sbjct: 136 PSSFNLALSQAFRGSPLGCVSTSLIPGESKDLAGRLHHSWHFA----GELQRALSAVSTR 191
Query: 220 NQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIE 279
++ +E E+ +E Y + E+ K +K A L+E
Sbjct: 192 HKKADRYIE-------ELTKERDALSLELYRNTITNEELK---KKNAELQE--------- 232
Query: 280 EANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERY 339
K+ AE E + EL R +ER + Q+Q L+ E E +++
Sbjct: 233 ----KLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKI 288
Query: 340 QQLEEASASLRERIRHLDDMVHCQQKKV----KQMVEENNELQSRLDYLTETQAKTEVE 394
++ EE ER+R + + Q++K+ K++ E+ EL+ + L E + E E
Sbjct: 289 RKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQE 347
Score = 45.4 bits (106), Expect = 1e-04
Identities = 54/285 (18%), Positives = 125/285 (43%), Gaps = 34/285 (11%)
Query: 38 ESPVPEQCEKKIERKEQLLDLSNGE-PTRKLPQGV--VYGVVRRSDQNQQKEMVVYGWST 94
E + EQ EK E++E++ + ++LP+ ++ + +Q + +E W
Sbjct: 630 EEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQ 689
Query: 95 SQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQS 154
+++++ + EK+R+ + MR++ +++ +E + Q+E ++ +
Sbjct: 690 EKMEKKTQEQEKKTWDQEKMREE-----ESMREREKKMREEEEMMREQEEKMQEQEEK-- 742
Query: 155 SALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNL--QQTYEASMDKLREKQRQ 212
+Q+ ++ + + +Q + QQ +KL E ++
Sbjct: 743 -------------------MQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 783
Query: 213 LEVAQVENQLLKMK-VESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEET 271
E ++ Q KM+ E E MR +K+ Q EEK+ ++ K ++E + +
Sbjct: 784 QEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQ-EEKMWGQEEKMWGQEEKMWGQE 842
Query: 272 NSFLKAIEEANKKMQAAEISLEEKDQRI-GELDRLIERMEKERHQ 315
E+ +KMQ E + E+++++ G+ +++ E+ EK R Q
Sbjct: 843 EKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQ 887
Score = 32.7 bits (73), Expect = 0.67
Identities = 47/244 (19%), Positives = 104/244 (42%), Gaps = 29/244 (11%)
Query: 41 VPEQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEE 100
+PEQ EK E ++ E K+ + + + Q Q+K+ W +++EE
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWE---QEKMEKKTQEQEKKT----WDQEKMREE 712
Query: 101 MNYIKDVRATLEKVRKR--MYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALD 158
+ +R +K+R+ M + +E Q+ + QE +QE + +
Sbjct: 713 ----ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQ 768
Query: 159 RFNAMNSAL-ASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQL---- 213
R L + + Q+ + + + + ++++R ++ +K+R ++ ++
Sbjct: 769 RLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQE 828
Query: 214 -----EVAQVENQLLKM-----KVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAE 263
+ ++ Q KM K+E + E MRE +K+ Q EEK++E++ K +
Sbjct: 829 EKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQ-EEKMREQEEKMRGQ 887
Query: 264 KEAL 267
+E +
Sbjct: 888 EEKI 891
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 70.1 bits (170), Expect = 4e-12
Identities = 83/407 (20%), Positives = 176/407 (43%), Gaps = 51/407 (12%)
Query: 44 QCEKKIERKEQLL--DLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEM 101
+ EK KE+LL + S + KL + + +++S + +++++ ++L+E
Sbjct: 931 ELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAAL---EARLEEST 987
Query: 102 NYIKDVRATLEKVRK-----RMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSA 156
NY + +R L+ V+K + D + M Q ++ E + + + +
Sbjct: 988 NYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDR 1047
Query: 157 LDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVA 216
L N+ L ++ L+ L + +N+N++ QI LQ+ + ++ Q Q
Sbjct: 1048 LIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKL 1107
Query: 217 QVENQLLKMKVESSQEANAEVM----------------REMTKKLYSQY---EEKLQEEQ 257
QVEN L + S NA+++ RE K LY EKL+
Sbjct: 1108 QVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLH 1167
Query: 258 RKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI----GELDRLIERMEKER 313
+ ++E E+L+ + + ++ A+K ++ LE++ ++ G+L+ L + ++ E+
Sbjct: 1168 ERQASEYESLISKHGT----LKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQ 1223
Query: 314 HQLQLQLLEHET------EMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKV 367
++ L+ HET ++ GE D Y QL + + L+ ++L +++ +
Sbjct: 1224 EKMLLENKNHETVAAEYKKLCGE-NDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKL-- 1280
Query: 368 KQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTRE 414
E L++ L E + ++ + ++ C+LL G E
Sbjct: 1281 -----EQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEE 1322
Score = 61.2 bits (147), Expect = 2e-09
Identities = 71/332 (21%), Positives = 157/332 (47%), Gaps = 34/332 (10%)
Query: 98 KEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHI-QTQSSA 156
++++ + + TLE +K+ + + ++ Q+++ +S A Q+ L + + + SS
Sbjct: 402 RKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSR 461
Query: 157 LDRFNAMNSALASDSIGLQKTLVDVTLENSNI---KDQIRNLQQTYEASMDKLREKQRQL 213
L + N +L L+ T+ V S I + + + L + E +++ ++++ L
Sbjct: 462 LLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSL 521
Query: 214 EVAQVENQLLKMKVESSQEANAEVMREMTK---KLYSQYEEKLQE-------------EQ 257
+ Q ++ L MK ++ E E +RE ++ K+ Q E L + E
Sbjct: 522 QNCQNLSKDL-MKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Query: 258 RKHSAEKE-----ALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKE 312
R EKE ++ET+S L IE ++++ +EK +R EL+ + +EKE
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640
Query: 313 RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERI---RHLDDMVHCQQKKVKQ 369
LQ ++ +++ E ++ ++ +LE + L++ + ++L + +K+ Q
Sbjct: 641 NELLQKKIT--NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQ 698
Query: 370 MVEENNELQSRLDYL---TETQAKTEVETREI 398
+ EEN EL+ ++ L + A+ ++E +E+
Sbjct: 699 LDEENLELRRNVESLKCASMKMAQLQLENKEL 730
Score = 60.5 bits (145), Expect = 3e-09
Identities = 80/349 (22%), Positives = 155/349 (44%), Gaps = 60/349 (17%)
Query: 96 QLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQEL---SVSHAQQEYLENHIQT 152
+LK+ ++ K++ LE + K DE ++R+ + L S+ AQ + +++
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKEN-SQLDEENLELRRNVESLKCASMKMAQLQLENKELES 732
Query: 153 QSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQ 212
+ L + + A + L+ + + +EN + LQ+T E S K+++ + +
Sbjct: 733 EKEQLKKGLELLKASFKKTERLEVSYQGLDIEN-------QRLQKTLENSNKKIQQLESE 785
Query: 213 LEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETN 272
L+ ++ENQ L + N E ++ +K+L +E EQ EK+
Sbjct: 786 LQDLEMENQTL--------QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK------ 831
Query: 273 SFLKAIEEANKKM-QAAEI---SLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMS 328
K +E+ NK++ Q AEI +LEE + +IG L++ + + KE + E
Sbjct: 832 ---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE--------IGIYKESC 880
Query: 329 GELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQ 388
L + +KE + ++ A+ ++ + +D+V ++ K +QM NN+L+
Sbjct: 881 VRLKELEKENKELVKRATIDIKTLVTLREDLV-SEKLKTQQM---NNDLE---------- 926
Query: 389 AKTEVETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLELTMKKTL 437
K E +IG+ + L T + Y LE T+KK+L
Sbjct: 927 -KLTHELEKIGLNKERLLHDEQSTDD-----SRYKLLESKLESTLKKSL 969
Score = 59.3 bits (142), Expect = 7e-09
Identities = 59/273 (21%), Positives = 120/273 (43%), Gaps = 11/273 (4%)
Query: 115 RKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASD--SI 172
R+ + + + + KIR+L QEL Q + ++ L R N L SD S
Sbjct: 246 RQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA 305
Query: 173 GLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQE 232
+ + +D E + D++ + Y+ + + + ++E + +NQ+L ++ ++ E
Sbjct: 306 RMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVL-LETKTMLE 364
Query: 233 ANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISL 292
E R + KL+ +E LQ + + H E E ++ ++ + E N ++ A+
Sbjct: 365 DQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK--IEELMEENMTLEMAQKQS 422
Query: 293 EEKDQRIG-ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRE 351
++ +G EL+++ E + + L HE ELT S + + ++ E
Sbjct: 423 MDESLHLGWELEQI--SRTSELSEAPQKSLGHEV---NELTSSRLLKLEMENQSLTKTVE 477
Query: 352 RIRHLDDMVHCQQKKVKQMVEENNELQSRLDYL 384
+R D V K+ +M +EN L +++ L
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 510
Score = 47.8 bits (112), Expect = 2e-05
Identities = 79/409 (19%), Positives = 173/409 (42%), Gaps = 78/409 (19%)
Query: 44 QCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNY 103
QC+KK E E++ L + V ++ NQ+ + + + +E
Sbjct: 134 QCQKKEEFIERIQGLDFDT------KAAVAAHIQEVTHNQENVFDLQWMEVTDMSQE--- 184
Query: 104 IKDVRATLEKVR---KRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRF 160
D+ L+ + KR+ + DE + I +L++E H +L + SSA
Sbjct: 185 --DIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLH----FLPH---ASSSA---- 231
Query: 161 NAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVEN 220
S S + ++ +++E ++ K +IR L+Q E ++L + +++LE ++E
Sbjct: 232 ---QSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIEL 288
Query: 221 QLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEE 280
+ L Q+ N ++ + R + E +AL E KA+
Sbjct: 289 KRL-------QQENMNLLSDA-------------RSARMYRDELDALRE------KAV-- 320
Query: 281 ANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGEL--TDSDKER 338
++ E + +R+ +++ R+E+ + Q+ LLE +T + +L T + ++
Sbjct: 321 ---RVDKLESEVSRYKERLHDIEFYKARVEELKEDNQV-LLETKTMLEDQLEGTRARSDK 376
Query: 339 YQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQS--------------RLDYL 384
+LE+ + L+ ++ ++ +KK+++++EEN L+ L+ +
Sbjct: 377 LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQI 436
Query: 385 TETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLELTM 433
+ T +E + +G + L S R ++ M +++ T L T+
Sbjct: 437 SRTSELSEAPQKSLGHEVNELTS--SRLLKLEMENQSLTKTVEELRTTV 483
Score = 43.9 bits (102), Expect = 3e-04
Identities = 70/351 (19%), Positives = 136/351 (38%), Gaps = 40/351 (11%)
Query: 81 QNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSH 140
Q +E+ + QL++E ++ + LEK +K++ + +RQ+ L ++
Sbjct: 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Query: 141 AQQEYLENHIQTQSS----------ALDRFNAMNSALASDS-------IGLQKTLVDVTL 183
+ LE +T S L N L + + L++ LV L
Sbjct: 857 VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKL 916
Query: 184 ENSNIKDQIRNLQQTYE-ASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMT 242
+ + + + L E ++K R + +LL+ K+ES+ + + E+ E
Sbjct: 917 KTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKI 976
Query: 243 KKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGEL 302
L ++ EE Q+ L + +K EA K+ Q E ++ GE
Sbjct: 977 AALEARLEESTNYNQQ---------LRQELKTVKKNYEALKQRQDEERMVQSSPPISGE- 1026
Query: 303 DRLIERMEKERHQLQLQLLEH--ETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV 360
D ER +E + L++ + E E + ++K Q L+ L + +L +
Sbjct: 1027 DNKWERESQETTRELLKVKDRLIEVERNNATLQAEK---QALKTQLKQLETQNNNLQAQI 1083
Query: 361 HCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGR 411
Q++ + E+N LQ++ AK +VE + L +Q +
Sbjct: 1084 LALQRQTVSLQEQNTTLQTQ-------NAKLQVENSTLNSQSTSLMNQNAQ 1127
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 70.1 bits (170), Expect = 4e-12
Identities = 83/406 (20%), Positives = 176/406 (43%), Gaps = 50/406 (12%)
Query: 44 QCEKKIERKEQLL-DLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMN 102
+ EK KE+LL D + + KL + + +++S + +++++ ++L+E N
Sbjct: 931 ELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAAL---EARLEESTN 987
Query: 103 YIKDVRATLEKVRK-----RMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSAL 157
Y + +R L+ V+K + D + M Q ++ E + + + + L
Sbjct: 988 YNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRL 1047
Query: 158 DRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQ 217
N+ L ++ L+ L + +N+N++ QI LQ+ + ++ Q Q Q
Sbjct: 1048 IEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQ 1107
Query: 218 VENQLLKMKVESSQEANAEVM----------------REMTKKLYSQY---EEKLQEEQR 258
VEN L + S NA+++ RE K LY EKL+
Sbjct: 1108 VENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHE 1167
Query: 259 KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRI----GELDRLIERMEKERH 314
+ ++E E+L+ + + ++ A+K ++ LE++ ++ G+L+ L + ++ E+
Sbjct: 1168 RQASEYESLISKHGT----LKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQE 1223
Query: 315 QLQLQLLEHET------EMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVK 368
++ L+ HET ++ GE D Y QL + + L+ ++L +++ +
Sbjct: 1224 KMLLENKNHETVAAEYKKLCGE-NDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKL--- 1279
Query: 369 QMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTRE 414
E L++ L E + ++ + ++ C+LL G E
Sbjct: 1280 ----EQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEE 1321
Score = 61.2 bits (147), Expect = 2e-09
Identities = 71/332 (21%), Positives = 157/332 (47%), Gaps = 34/332 (10%)
Query: 98 KEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHI-QTQSSA 156
++++ + + TLE +K+ + + ++ Q+++ +S A Q+ L + + + SS
Sbjct: 402 RKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSR 461
Query: 157 LDRFNAMNSALASDSIGLQKTLVDVTLENSNI---KDQIRNLQQTYEASMDKLREKQRQL 213
L + N +L L+ T+ V S I + + + L + E +++ ++++ L
Sbjct: 462 LLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSL 521
Query: 214 EVAQVENQLLKMKVESSQEANAEVMREMTK---KLYSQYEEKLQE-------------EQ 257
+ Q ++ L MK ++ E E +RE ++ K+ Q E L + E
Sbjct: 522 QNCQNLSKDL-MKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEA 580
Query: 258 RKHSAEKE-----ALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKE 312
R EKE ++ET+S L IE ++++ +EK +R EL+ + +EKE
Sbjct: 581 RVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKE 640
Query: 313 RHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERI---RHLDDMVHCQQKKVKQ 369
LQ ++ +++ E ++ ++ +LE + L++ + ++L + +K+ Q
Sbjct: 641 NELLQKKIT--NLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQ 698
Query: 370 MVEENNELQSRLDYL---TETQAKTEVETREI 398
+ EEN EL+ ++ L + A+ ++E +E+
Sbjct: 699 LDEENLELRRNVESLKCASMKMAQLQLENKEL 730
Score = 60.5 bits (145), Expect = 3e-09
Identities = 80/349 (22%), Positives = 155/349 (44%), Gaps = 61/349 (17%)
Query: 96 QLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQEL---SVSHAQQEYLENHIQT 152
+LK+ ++ K++ LE + K DE ++R+ + L S+ AQ + +++
Sbjct: 674 KLKKTLDSFKNLTFQLESLEKEN-SQLDEENLELRRNVESLKCASMKMAQLQLENKELES 732
Query: 153 QSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQ 212
+ L + + A + L+ + + +EN + LQ+T E S K+++ + +
Sbjct: 733 EKEQLKKGLELLKASFKKTERLEVSYQGLDIEN-------QRLQKTLENSNKKIQQLESE 785
Query: 213 LEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETN 272
L+ ++ENQ L + N E ++ +K+L +E EQ EK+
Sbjct: 786 LQDLEMENQTL--------QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDK------ 831
Query: 273 SFLKAIEEANKKM-QAAEI---SLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMS 328
K +E+ NK++ Q AEI +LEE + +IG L++ + + KE + E
Sbjct: 832 ---KQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKE--------IGIYKESC 880
Query: 329 GELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQ 388
L + +KE + ++ A+ ++ + +D+V ++ K +QM NN+L+
Sbjct: 881 VRLKELEKENKELVKRATIDIKTLVTLREDLV-SEKLKTQQM---NNDLE---------- 926
Query: 389 AKTEVETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLELTMKKTL 437
K E +IG+ + L T + Y LE T+KK+L
Sbjct: 927 -KLTHELEKIGLNKERLLHDEQSTDD------RYKLLESKLESTLKKSL 968
Score = 59.3 bits (142), Expect = 7e-09
Identities = 59/273 (21%), Positives = 120/273 (43%), Gaps = 11/273 (4%)
Query: 115 RKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASD--SI 172
R+ + + + + KIR+L QEL Q + ++ L R N L SD S
Sbjct: 246 RQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSA 305
Query: 173 GLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQE 232
+ + +D E + D++ + Y+ + + + ++E + +NQ+L ++ ++ E
Sbjct: 306 RMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVL-LETKTMLE 364
Query: 233 ANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISL 292
E R + KL+ +E LQ + + H E E ++ ++ + E N ++ A+
Sbjct: 365 DQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKK--IEELMEENMTLEMAQKQS 422
Query: 293 EEKDQRIG-ELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRE 351
++ +G EL+++ E + + L HE ELT S + + ++ E
Sbjct: 423 MDESLHLGWELEQI--SRTSELSEAPQKSLGHEV---NELTSSRLLKLEMENQSLTKTVE 477
Query: 352 RIRHLDDMVHCQQKKVKQMVEENNELQSRLDYL 384
+R D V K+ +M +EN L +++ L
Sbjct: 478 ELRTTVDSVEGNASKILKMEKENQRLSKKVEIL 510
Score = 47.8 bits (112), Expect = 2e-05
Identities = 79/409 (19%), Positives = 173/409 (42%), Gaps = 78/409 (19%)
Query: 44 QCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNY 103
QC+KK E E++ L + V ++ NQ+ + + + +E
Sbjct: 134 QCQKKEEFIERIQGLDFDT------KAAVAAHIQEVTHNQENVFDLQWMEVTDMSQE--- 184
Query: 104 IKDVRATLEKVR---KRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRF 160
D+ L+ + KR+ + DE + I +L++E H +L + SSA
Sbjct: 185 --DIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLH----FLPH---ASSSA---- 231
Query: 161 NAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVEN 220
S S + ++ +++E ++ K +IR L+Q E ++L + +++LE ++E
Sbjct: 232 ---QSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIEL 288
Query: 221 QLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEE 280
+ L Q+ N ++ + R + E +AL E KA+
Sbjct: 289 KRL-------QQENMNLLSDA-------------RSARMYRDELDALRE------KAV-- 320
Query: 281 ANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGEL--TDSDKER 338
++ E + +R+ +++ R+E+ + Q+ LLE +T + +L T + ++
Sbjct: 321 ---RVDKLESEVSRYKERLHDIEFYKARVEELKEDNQV-LLETKTMLEDQLEGTRARSDK 376
Query: 339 YQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQS--------------RLDYL 384
+LE+ + L+ ++ ++ +KK+++++EEN L+ L+ +
Sbjct: 377 LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQI 436
Query: 385 TETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLELTM 433
+ T +E + +G + L S R ++ M +++ T L T+
Sbjct: 437 SRTSELSEAPQKSLGHEVNELTS--SRLLKLEMENQSLTKTVEELRTTV 483
Score = 43.5 bits (101), Expect = 4e-04
Identities = 74/352 (21%), Positives = 141/352 (40%), Gaps = 43/352 (12%)
Query: 81 QNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSH 140
Q +E+ + QL++E ++ + LEK +K++ + +RQ+ L ++
Sbjct: 797 QKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENN 856
Query: 141 AQQEYLENHIQTQSS----------ALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKD 190
+ LE +T S L N L + KTL VTL + +
Sbjct: 857 VKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTL--VTLREDLVSE 914
Query: 191 QIRNLQQTYEA-----SMDKL-REKQRQLEVAQVEN---QLLKMKVESSQEANAEVMREM 241
+++ Q + ++K+ K+R L Q + +LL+ K+ES+ + + E+ E
Sbjct: 915 KLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEK 974
Query: 242 TKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGE 301
L ++ EE Q+ L + +K EA K+ Q E ++ GE
Sbjct: 975 IAALEARLEESTNYNQQ---------LRQELKTVKKNYEALKQRQDEERMVQSSPPISGE 1025
Query: 302 LDRLIERMEKERHQLQLQLLEH--ETEMSGELTDSDKERYQQLEEASASLRERIRHLDDM 359
D ER +E + L++ + E E + ++K Q L+ L + +L
Sbjct: 1026 -DNKWERESQETTRELLKVKDRLIEVERNNATLQAEK---QALKTQLKQLETQNNNLQAQ 1081
Query: 360 VHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGR 411
+ Q++ + E+N LQ++ AK +VE + L +Q +
Sbjct: 1082 ILALQRQTVSLQEQNTTLQTQ-------NAKLQVENSTLNSQSTSLMNQNAQ 1126
>gi|121582655 ankyrin repeat domain 35 [Homo sapiens]
Length = 1001
Score = 70.1 bits (170), Expect = 4e-12
Identities = 94/420 (22%), Positives = 178/420 (42%), Gaps = 69/420 (16%)
Query: 33 LTVPPESPVPEQCE----------KKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQN 82
L V PE P E E K+ E KE+ + + GEP L G + +
Sbjct: 555 LQVKPEVPSQESREGALKAAPGSIKQDEEKEKRVPGARGEPLGALGGEKALGGLAKGQL- 613
Query: 83 QQKEMVVYGWSTSQLKEEMNYIKDVRATLEK----VRKRMYGDY----------DEMRQK 128
+KEM V S S L EE+ + R L++ + +R+ ++ ++RQ
Sbjct: 614 -EKEMSVLRLSNSNLLEELGELGRERQRLQRELQSLSQRLQREFVPKPEAQVQLQQLRQS 672
Query: 129 IRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQK------------ 176
+ LT EL++ E L + +QSS L + L +D +G +
Sbjct: 673 VGLLTNELAMEKEATEKLRKLLASQSSGL---RGLWDCLPADLVGERSAQSKAAESLEEL 729
Query: 177 -----TLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQL------EVAQVENQLLKM 225
TLVD E + +++ Q S+ RE L +VA +E L K+
Sbjct: 730 RACISTLVDRHREAQQVLARLQEENQQLRGSLSPCREPGTSLKAPASPQVAALEQDLGKL 789
Query: 226 K-----VESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEE 280
+ V+++ ++ + ++ + LY EE + R+ ++ ++ E+T L A +
Sbjct: 790 EEELRAVQATMSGKSQEIGKLKQLLYQATEEVAELRAREAASLRQH--EKTRGSLVA--Q 845
Query: 281 ANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQ---LQLQLLEHETEMSGELTDSDKE 337
A Q + LE+ + E+ RL E + +ER + L Q E E + S +
Sbjct: 846 AQAWGQELKALLEKYNTACREVGRLREAVAEERRRSGDLAAQAAEQERQAS-----EMRG 900
Query: 338 RYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETRE 397
R +Q E+ + L+E++ HL ++ K+K+++++ +L + + A+ ++ ++
Sbjct: 901 RSEQFEKTAELLKEKMEHLIGACRDKEAKIKELLKKLEQLSEEVLAIRGENARLALQLQD 960
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 69.7 bits (169), Expect = 5e-12
Identities = 78/333 (23%), Positives = 148/333 (44%), Gaps = 63/333 (18%)
Query: 96 QLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSS 155
Q+ E+ N +KD+ LE+ R ++ +++ +K + ++ L S +Q +L ++
Sbjct: 274 QITEKENKMKDLTFLLEESRDKV----NQLEEKTKLQSENLKQSIEKQHHLTKELEDIKV 329
Query: 156 ALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQ-----------IRNLQQTYEASMD 204
+L R + AL D KT+ +T E ++ + + T + +
Sbjct: 330 SLQRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEE 389
Query: 205 KLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK 264
LR +Q++LE + + ++L M+++ + EMTK L + E +L EE +K EK
Sbjct: 390 LLRTEQQRLEKNEDQLKILTMELQKKSSE----LEEMTK-LTNNKEVEL-EELKKVLGEK 443
Query: 265 EALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQL---- 320
E LL E F K EE Q EL L++ EKE H L++QL
Sbjct: 444 ETLLYENKQFEKIAEELKGTEQ--------------ELIGLLQAREKEVHDLEIQLTAIT 489
Query: 321 ----------------LEHETEMSGELTDSDKE---RYQQLEEASASLRERIRHLDDMVH 361
LE+E + ELT + ++L + ++ + +++ + ++
Sbjct: 490 TSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN 549
Query: 362 CQQKKVKQMVEENNELQSRLDYLTETQAKTEVE 394
+K+ ++M+++ LQ TETQ + E+E
Sbjct: 550 NNKKQEERMLKQIENLQE-----TETQLRNELE 577
Score = 53.5 bits (127), Expect = 4e-07
Identities = 63/310 (20%), Positives = 124/310 (40%), Gaps = 31/310 (10%)
Query: 104 IKDVRATLEKVRKR---MYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRF 160
+KD++ LE + + + +++ + ++LTQE S + + + I +R
Sbjct: 499 VKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERM 558
Query: 161 NAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLRE----KQRQLEVA 216
L L+ L V E +D+++ E + + LR+ K + +E
Sbjct: 559 LKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLRKQVENKNKYIEEL 618
Query: 217 QVENQLLKMK-VESSQEANA--------EVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL 267
Q EN+ LK K S++ N E+ E K+ + + + Q+E +E L
Sbjct: 619 QQENKALKKKGTAESKQLNVYEIKVNKLELELESAKQKFGEITDTYQKEIEDKKISEENL 678
Query: 268 LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEM 327
LEE +EA K + + + K + ++ MEK +HQ + E ++E+
Sbjct: 679 LEEVEKAKVIADEAVKLQKEIDKRCQHK------IAEMVALMEKHKHQYDKIIEERDSEL 732
Query: 328 SGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTET 387
Y+ E+ +SLR + + + VK+ +E E + +L +
Sbjct: 733 G---------LYKSKEQEQSSLRASLEIELSNLKAELLSVKKQLEIEREEKEKLKREAKE 783
Query: 388 QAKTEVETRE 397
T E ++
Sbjct: 784 NTATLKEKKD 793
Score = 53.5 bits (127), Expect = 4e-07
Identities = 62/288 (21%), Positives = 130/288 (45%), Gaps = 25/288 (8%)
Query: 116 KRMYGDYDEMRQKIRQLTQELSVSHAQQE----YLENHIQTQSSALDRFNAMNSALASDS 171
K + + +M +++ ++++ + Q+E +EN +T++ + + L
Sbjct: 528 KELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQLRNELEYVREELKQKR 587
Query: 172 IGLQKTLVDVTLEN-SNIKDQIRN-------LQQTYEASMDKLREKQRQLEVAQVENQLL 223
+ K +D + EN +N++ Q+ N LQQ +A K + +QL V +++ L
Sbjct: 588 DEV-KCKLDKSEENCNNLRKQVENKNKYIEELQQENKALKKKGTAESKQLNVYEIKVNKL 646
Query: 224 KMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK-EALLEETNSFLKAIEEAN 282
++++ES+++ E+ K++ ++K+ EE EK + + +E K I++
Sbjct: 647 ELELESAKQKFGEITDTYQKEI---EDKKISEENLLEEVEKAKVIADEAVKLQKEIDKRC 703
Query: 283 KKMQAAEISLEEK-----DQRIGELDR---LIERMEKERHQLQLQLLEHETEMSGELTDS 334
+ A ++L EK D+ I E D L + E+E+ L+ L + + EL
Sbjct: 704 QHKIAEMVALMEKHKHQYDKIIEERDSELGLYKSKEQEQSSLRASLEIELSNLKAELLSV 763
Query: 335 DKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLD 382
K+ + EE RE + + + KK + + E E+ +LD
Sbjct: 764 KKQLEIEREEKEKLKREAKENTATLKEKKDKKTQTFLLETPEIYWKLD 811
Score = 47.8 bits (112), Expect = 2e-05
Identities = 60/271 (22%), Positives = 113/271 (41%), Gaps = 35/271 (12%)
Query: 112 EKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDS 171
EK++K E+RQK +L + + AQ++ ++ L N S +
Sbjct: 114 EKIKKWKVSTEAELRQKESKLQENRKIIEAQRKAIQE--------LQFGNEKVSLKLEEG 165
Query: 172 IGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQ 231
I K L+ EN+ + L++T S EK ++ E + E + + M + +
Sbjct: 166 IQENKDLIK---ENNATRHLCNLLKETCARSA----EKTKKYEYEREETRQVYMDLNN-- 216
Query: 232 EANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEIS 291
N E M ++L Q E E K + E + + K I + K++ I
Sbjct: 217 --NIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQ 274
Query: 292 LEEKDQRIGELDRLIERME------KERHQLQLQLLEHETEMSGELTDSDKERYQQLEEA 345
+ EK+ ++ +L L+E +E+ +LQ + L+ E LT ++LE+
Sbjct: 275 ITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLT-------KELEDI 327
Query: 346 SASLRERI---RHLDDMVHCQQKKVKQMVEE 373
SL+ + + L++ + K + Q+ EE
Sbjct: 328 KVSLQRSVSTQKALEEDLQIATKTICQLTEE 358
Score = 34.7 bits (78), Expect = 0.18
Identities = 43/204 (21%), Positives = 83/204 (40%), Gaps = 17/204 (8%)
Query: 186 SNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESS---QEANAEVMREMT 242
S +K Q T+ S +K E + A+ ++S Q+ N + E
Sbjct: 21 SAVKPQTLGGDSTFFKSFNKCTEDDFEFPFAKTNLSKNGENIDSDPALQKVNFLPVLEQV 80
Query: 243 KKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGEL 302
Y+E L++ ++S E L + K E+ K + E L +K+ ++ E
Sbjct: 81 GNSDCHYQEGLKDSDLENS---EGLSRVYSKLYKEAEKIKKWKVSTEAELRQKESKLQEN 137
Query: 303 DRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVH- 361
++IE K +LQ ++S +L + +E ++E +A+ RHL +++
Sbjct: 138 RKIIEAQRKAIQELQF----GNEKVSLKLEEGIQENKDLIKENNAT-----RHLCNLLKE 188
Query: 362 -CQQKKVKQMVEENNELQSRLDYL 384
C + K E ++R Y+
Sbjct: 189 TCARSAEKTKKYEYEREETRQVYM 212
>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
Length = 1711
Score = 69.7 bits (169), Expect = 5e-12
Identities = 86/401 (21%), Positives = 179/401 (44%), Gaps = 46/401 (11%)
Query: 43 EQCEKKIERKEQLLDLSNGEPTRKLPQGV-----VYGVVRR-SDQNQQKEMVVYGWSTSQ 96
E E++I R EQ E +RKL + ++G R S+ N+ KE+ +
Sbjct: 441 EAYERRIRRLEQ----EKLELSRKLQESTQTVQSLHGSSRALSNSNRDKEI-------KK 489
Query: 97 LKEEMNYIKDVRATLEKVRKRMYG------DYDEMRQKIRQLTQELSVSHAQQEYLENHI 150
L EE+ +K+ A ++ +++ + ++ Q++R L ++ V ++E L +
Sbjct: 490 LNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQL 549
Query: 151 -------QTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEAS- 202
++Q+ L + + L + + ++ + + Q+R+ ++ E +
Sbjct: 550 VEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVAT 609
Query: 203 --MDKLREKQRQLEVA--QVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
+D +R++ R+ E ++E QL E+S+E +RE ++ Q E +L+ +
Sbjct: 610 QKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERK---LREHSENFCKQMESELEALKV 666
Query: 259 KHSAEKE-ALLEETNSFLKAIEEANKKMQAAEISLEEKD-QRIGELDRLIERM-EKERHQ 315
K A LE K E KK+ E L ++ + E+ + + + + E HQ
Sbjct: 667 KQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVHDSESHQ 726
Query: 316 LQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENN 375
L LQ + + +L S +ER+ ++EEA +++++ M+ + KK + EN
Sbjct: 727 LALQ--KEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKK---LTAENE 781
Query: 376 ELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTREIV 416
+L S +D LT + E E +++ + + + EI+
Sbjct: 782 KLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAEII 822
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 69.3 bits (168), Expect = 6e-12
Identities = 73/365 (20%), Positives = 166/365 (45%), Gaps = 49/365 (13%)
Query: 43 EQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMN 102
++ E+KI+ +E+ + E K+ + + +Q+EM+ + +EEM
Sbjct: 310 QEWEEKIQEQEEKIR----EQEEKIRE-------QEEKMRRQEEMMWEKEEKMRRQEEMM 358
Query: 103 YIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNA 162
+ K+ + + ++ + M+ E +KIR+L +++ H Q++ E + Q R
Sbjct: 359 WEKEEK--MRRLEEMMW----EKEEKIRELEEKM---HEQEKIREQEEKRQEEEKIREQE 409
Query: 163 MNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEA--SMDKLREKQRQLEVAQVEN 220
+ ++ + + + I++Q + + + E +K+RE++++ E ++
Sbjct: 410 KRQEQEAKMWRQEEKIRE---QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 466
Query: 221 QLLKMKVESSQEANAEVMREMTK-------------KLYSQYEEKLQEEQRKHSAEKEAL 267
Q K++ + E M E K K++ Q EEK++E++ K ++E +
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQ-EEKIREQEEKMWRQEEKI 525
Query: 268 LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEM 327
E+ I E +K++ E ++E+++++GE + ++ EK R Q E +
Sbjct: 526 REQEEK----IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ------EEKIRE 575
Query: 328 SGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTET 387
E KE+ ++ EE E+IR ++M+ Q++K+ + E+ E + ++ E
Sbjct: 576 QEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 635
Query: 388 QAKTE 392
+ E
Sbjct: 636 MRRQE 640
Score = 58.2 bits (139), Expect = 1e-08
Identities = 48/241 (19%), Positives = 112/241 (46%), Gaps = 14/241 (5%)
Query: 165 SALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLK 224
SA+A+ + + ++T E + ++ T E +K + Q +L++ + E ++
Sbjct: 182 SAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQ 241
Query: 225 MKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKK 284
+ V+ + + ++ + L +E + SA+ +A +EE + + ++ +K
Sbjct: 242 LNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEK 301
Query: 285 M-------QAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEM--SGELTDSD 335
M Q E ++E++++I E + I E++ + + + E E +M E+
Sbjct: 302 MWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEK 361
Query: 336 KERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVET 395
+E+ ++LEE E+IR L++ +H Q+K + E E + + + E + + E E
Sbjct: 362 EEKMRRLEEMMWEKEEKIRELEEKMHEQEK-----IREQEEKRQEEEKIREQEKRQEQEA 416
Query: 396 R 396
+
Sbjct: 417 K 417
Score = 44.7 bits (104), Expect = 2e-04
Identities = 29/148 (19%), Positives = 73/148 (49%), Gaps = 6/148 (4%)
Query: 189 KDQIRNLQQTYEASMDKLREKQRQLEVAQVE--NQLLKMKVESSQEANAEVMREMTKKLY 246
+++IR ++ +K+RE++ ++ + + Q KM+ + E +RE +K+
Sbjct: 522 EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIR 581
Query: 247 SQYEEKLQEEQRKHSAEKEALLEETNSFLKAIE---EANKKMQAAEISLEEKDQRIGELD 303
Q +EK++E++ K ++E + E+ + E E +KM E ++E+++++ +
Sbjct: 582 EQ-KEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 640
Query: 304 RLIERMEKERHQLQLQLLEHETEMSGEL 331
+ E Q + ++ EH+ + +
Sbjct: 641 EKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 43.9 bits (102), Expect = 3e-04
Identities = 56/258 (21%), Positives = 123/258 (47%), Gaps = 23/258 (8%)
Query: 38 ESPVPEQCEKKIERKEQLLDLSNG--EPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTS 95
E + EQ EKK+ R+E+ + E ++ Q ++ R+ ++ +++E + W
Sbjct: 429 EEKIREQ-EKKMWRQEEKIHEQEKIREEEKRQEQEEMW---RQEEKIREQEEI---W--- 478
Query: 96 QLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSS 155
+ KE+M+ + +R EKV ++ +D+ +KIR+ +++ + E I+ Q
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQ-EEKIREQEEKMWRQEEKIREQEEKIREQEE 537
Query: 156 ALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEV 215
+ M + +G Q+ + + +++IR ++ +K+RE++ ++
Sbjct: 538 KIREQEEMMQE-QEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI-- 594
Query: 216 AQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFL 275
+ + ++ + E QE E M E +K+ Q EEK+QE++ K ++E + E+
Sbjct: 595 -WEQEEKIREQEEMMQEQE-EKMWEQEEKMCEQ-EEKMQEQEEKMRRQEEKMWEQE---- 647
Query: 276 KAIEEANKKMQAAEISLE 293
+ + +KMQ + LE
Sbjct: 648 VRLRQQEEKMQEHQEHLE 665
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 69.3 bits (168), Expect = 6e-12
Identities = 87/396 (21%), Positives = 162/396 (40%), Gaps = 38/396 (9%)
Query: 76 VRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQE 135
++R Q +KE T L I + LEK+ + + E++ K + +
Sbjct: 1213 LQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQRL 1272
Query: 136 LSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIG-------LQKTLVDVTLENSNI 188
++ AQ+ L+ S LD +A+ S L+ L+ L + T + +
Sbjct: 1273 INDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEEETKAKNAL 1332
Query: 189 KDQIRN-------LQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREM 241
+++ L++ YE + E QR L A E + K E+ E + E
Sbjct: 1333 AHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEA 1392
Query: 242 TKKLYSQYEE-------------KLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAA 288
KKL + +E L++ +++ E E L+ + A +KK +
Sbjct: 1393 KKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNF 1452
Query: 289 EISLEEKDQRIGELDRLIERMEKERHQLQLQL--LEHETEMSGELTDSDKERYQQLEEAS 346
+ L E Q+ E +E +KE L +L +++ E S + ++ + + L++
Sbjct: 1453 DKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEI 1512
Query: 347 ASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLP 406
+ L E+I +H +K KQ+ +E E+Q+ L+ + E + I + + +
Sbjct: 1513 SDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVK 1572
Query: 407 SQTGR-----TREIVMPSRNYTPYTRVLELTMKKTL 437
S+ R EI RN +TRV+E TM+ TL
Sbjct: 1573 SEVDRKIAEKDEEIDQLKRN---HTRVVE-TMQSTL 1604
Score = 59.7 bits (143), Expect = 5e-09
Identities = 90/402 (22%), Positives = 163/402 (40%), Gaps = 47/402 (11%)
Query: 43 EQCEKK--IERKEQLLDLSNGEPTR-KLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKE 99
E+CE + +E E L+ G+ R +L V V R + +E+ + +++ E
Sbjct: 1539 EKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVE 1598
Query: 100 EMNYIKDV----RATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQ---EYLENHIQT 152
M D R +V+K+M GD +EM E+ ++HA + E L N+ T
Sbjct: 1599 TMQSTLDAEIRSRNDALRVKKKMEGDLNEM---------EIQLNHANRLAAESLRNYRNT 1649
Query: 153 QSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQ 212
Q + ++ AL L++ L V + ++ +I L T E + + +++
Sbjct: 1650 QGILKETQLHLDDALRGQE-DLKEQLAIVERRANLLQAEIEELWATLEQTERSRKIAEQE 1708
Query: 213 LEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETN 272
L A QLL + S ++ ++++ L S+ EE +QE + K+A+ +
Sbjct: 1709 LLDASERVQLLHTQNTSLINTKKKLENDVSQ-LQSEVEEVIQESRNAEEKAKKAITDAA- 1766
Query: 273 SFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQL-------QLQLLEHET 325
+ E KK Q LE + + + + ++ E QL Q+Q LE
Sbjct: 1767 ----MMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARV 1822
Query: 326 -EMSGELTDSDKE-------------RYQQLEEASASLRERIRHLDDMVHCQQKKVKQMV 371
E+ GE+ + K R ++L + R+ + L D+V Q KVK
Sbjct: 1823 RELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKVKSYK 1882
Query: 372 EENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTR 413
+ E + + + K + E E D+ SQ + R
Sbjct: 1883 RQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLR 1924
Score = 55.1 bits (131), Expect = 1e-07
Identities = 67/315 (21%), Positives = 144/315 (45%), Gaps = 43/315 (13%)
Query: 97 LKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSA 156
+KEE KD A E RK E+ +K+ L +E + L+ +Q+++ +
Sbjct: 855 MKEEFQKTKDELAKSEAKRK-------ELEEKMVTLLKE-------KNDLQLQVQSEADS 900
Query: 157 LDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVA 216
L L + I L+ + +VT E + +++I N + T A KL ++ +L+
Sbjct: 901 LADAEERCEQLIKNKIQLEAKIKEVT-ERAEEEEEI-NAELT--AKKRKLEDECSELKKD 956
Query: 217 QVENQLLKMKVESSQEANAEVMREMTKKL---------YSQYEEKLQEEQRKHSAEKEAL 267
+ +L KVE + A ++ +T+++ S+ ++ LQE ++ + +A
Sbjct: 957 IDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAE 1016
Query: 268 LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIER--------------MEKER 313
++ N KA + +++ E SLE++ + +L+R + ME ++
Sbjct: 1017 EDKVNILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDK 1076
Query: 314 HQLQLQLLEHETEMSGELTDSDKERYQ--QLEEASASLRERIRHLDDMVHCQQKKVKQMV 371
QL +L + E E+S ++ + E+ QL++ L+ RI L + + ++ +
Sbjct: 1077 QQLDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAE 1136
Query: 372 EENNELQSRLDYLTE 386
++ ++L L+ ++E
Sbjct: 1137 KQRSDLSRELEEISE 1151
Score = 52.0 bits (123), Expect = 1e-06
Identities = 64/320 (20%), Positives = 138/320 (43%), Gaps = 16/320 (5%)
Query: 109 ATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALA 168
A L+K ++ E +QK + EL S + L + + + L
Sbjct: 1443 AALDKKQRNFDKVLSEWKQKYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLR 1502
Query: 169 SDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQV-----ENQLL 223
++ LQ+ + D+T + + QI L++ + + E Q LE A+ E ++L
Sbjct: 1503 RENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKIL 1562
Query: 224 KMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANK 283
++++E +Q +EV R++ +K +E++ + +R H+ E + ++ +++ +A +
Sbjct: 1563 RIQLELNQ-VKSEVDRKIAEK-----DEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALR 1616
Query: 284 KMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSD--KERYQQ 341
+ E L E + ++ +RL + Q L E + + L + KE+
Sbjct: 1617 VKKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAI 1676
Query: 342 LEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVETREIGVG 401
+E + L+ I L + ++ K +E + R+ L TQ + + T++ +
Sbjct: 1677 VERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQ-LLHTQNTSLINTKK-KLE 1734
Query: 402 CDLLPSQTGRTREIVMPSRN 421
D+ Q+ E++ SRN
Sbjct: 1735 NDVSQLQS-EVEEVIQESRN 1753
Score = 48.5 bits (114), Expect = 1e-05
Identities = 49/211 (23%), Positives = 102/211 (48%), Gaps = 25/211 (11%)
Query: 183 LENSNIKDQIRNLQQTYEASMDKLRE---KQRQLEVAQV----ENQLLKMKVESSQE--A 233
L+++ + ++ +++ ++ + D+L + K+++LE V E L+++V+S + A
Sbjct: 843 LKSAETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLA 902
Query: 234 NAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLE 293
+AE E K Q E K++E + E+E E T A K+ E S
Sbjct: 903 DAEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELT---------AKKRKLEDECSEL 953
Query: 294 EKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERI 353
+KD I +L+ + ++EKE+H + ++ EM+G E +L + +L+E
Sbjct: 954 KKD--IDDLELTLAKVEKEKHATENKVKNLTEEMAGL-----DETIAKLSKEKKALQETH 1006
Query: 354 RHLDDMVHCQQKKVKQMVEENNELQSRLDYL 384
+ D + ++ KV + + +L+ ++D L
Sbjct: 1007 QQTLDDLQAEEDKVNILTKAKTKLEQQVDDL 1037
Score = 44.7 bits (104), Expect = 2e-04
Identities = 63/336 (18%), Positives = 142/336 (42%), Gaps = 35/336 (10%)
Query: 97 LKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSA 156
L+ + K +R LE+ ++++ GD ++ + + + E E I S
Sbjct: 1037 LEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISK 1096
Query: 157 LDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLR-EKQRQLEV 215
++ A+ I LQK + ++ + ++I ++ A +K R + R+LE
Sbjct: 1097 IEDEQAVE-------IQLQKKIKELQARIEELGEEIE-AERASRAKAEKQRSDLSRELE- 1147
Query: 216 AQVENQL--------LKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEAL 267
++ +L ++++ +EA + +R ++ Q+E + ++KH+ L
Sbjct: 1148 -EISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAEL 1206
Query: 268 LEETNSFLKAIEEANK-----KMQAAEIS--LEEKDQRIGELDRLIERMEKERHQLQLQL 320
E+ ++ + ++ K KM+ ++S E + G L+++ +E + +L+ +
Sbjct: 1207 GEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTK- 1265
Query: 321 LEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSR 380
E + + +LT + E S L E+ + + +Q +Q+ E ++L+
Sbjct: 1266 EEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQLEE- 1324
Query: 381 LDYLTETQAKTEV--ETREIGVGCDLLPSQTGRTRE 414
ET+AK + + CDLL Q +E
Sbjct: 1325 -----ETKAKNALAHALQSSRHDCDLLREQYEEEQE 1355
>gi|237858619 polyamine modulated factor 1 binding protein 1 isoform
a [Homo sapiens]
Length = 1007
Score = 68.9 bits (167), Expect = 8e-12
Identities = 81/382 (21%), Positives = 181/382 (47%), Gaps = 44/382 (11%)
Query: 43 EQC---EKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKE 99
+QC E ++ KE D S E K Q V + ++ +Q+E + +Q KE
Sbjct: 434 QQCMATELEMTVKEAKQDKSK-EAECKALQAEVQKLKNSLEEAKQQERLA-AQQAAQCKE 491
Query: 100 EMN----YIKDVRATLEK---VRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQT 152
E +++D + L+K + K+ E++++++ L +E S+ A++E N +
Sbjct: 492 EAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSM--AEKEQTSNRKRV 549
Query: 153 QSSALDRFNAMNSALASDSIG--LQKTLVDVTLENSNIKDQIRN-----------LQQTY 199
+ +L+ A+ SD LQKT+ + ++ +++ D+I++ L++
Sbjct: 550 EELSLELSEALRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDL 609
Query: 200 EASMDKLREKQRQLEVAQVENQLLKMKVESSQEA---NAEVMREMTKKLYSQYEEKLQEE 256
+ + L +K+ QL+ ++ +L++ ++E+ ++ + ++E ++KL + E L+ E
Sbjct: 610 QEATKLLEDKREQLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEE-NENLRAE 668
Query: 257 QRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQL 316
+ S + E+ L + N+ + I++ NK EI+L+ K+ + +L + ++KE+H L
Sbjct: 669 LQCCSTQLESSLNKYNTSQQVIQDLNK-----EIALQ-KESLMSLQAQLDKALQKEKHYL 722
Query: 317 QLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNE 376
Q T ++ E D+ + ++ E++ H+ Q+ + Q E+ +
Sbjct: 723 Q-------TTITKEAYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQ 775
Query: 377 LQSRLDYLTETQAKTEVETREI 398
L+ + E K E R++
Sbjct: 776 LEEEIIAYEERMKKLNTELRKL 797
Score = 50.8 bits (120), Expect = 2e-06
Identities = 78/404 (19%), Positives = 168/404 (41%), Gaps = 74/404 (18%)
Query: 97 LKEEMNYIKDVRATLEKVRKR--------------MYGDYDEMRQKIRQLTQELSVSHAQ 142
++E N +KD+R LE V ++ ++G +E I + +++++ +
Sbjct: 322 VEEYQNLVKDLRVELEAVSEQKRNIMKDMMKLELDLHGLREETSAHIERKDKDITILQCR 381
Query: 143 QEYLE-NHIQTQSSAL--DRF----NAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNL 195
+ L+ +TQ L D+F + M L +Q +L+ E + L
Sbjct: 382 LQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATEL 441
Query: 196 QQTY-EASMDKLRE---KQRQLEVAQVENQLLKMKVE---SSQEA--------------- 233
+ T EA DK +E K Q EV +++N L + K + ++Q+A
Sbjct: 442 EMTVKEAKQDKSKEAECKALQAEVQKLKNSLEEAKQQERLAAQQAAQCKEEAALAGCHLE 501
Query: 234 ---------------NAEVMREMTKKLYSQYEEKLQEEQRKHSAEK--EALLEETNSFLK 276
A+ ++E+ ++L +E E+ + S K E L E + L+
Sbjct: 502 DTQRKLQKGLLLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALR 561
Query: 277 AIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTD--- 333
+E ++K+ + + ++ E+D ++ ++ I+ +E+ ++ +L E E + L D
Sbjct: 562 KLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEATKLLEDKRE 621
Query: 334 ---SDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEE--------NNELQSRLD 382
KE + +E +LR+ + D + +K+++ E + +L+S L+
Sbjct: 622 QLKKSKEHEKLMEGELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLN 681
Query: 383 YLTETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSRNYTPYT 426
+Q + +EI + + L S + + + ++Y T
Sbjct: 682 KYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTT 725
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/193 (22%), Positives = 83/193 (43%), Gaps = 21/193 (10%)
Query: 94 TSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQ 153
++QL+ +N + ++ + K + + + QL + L ++ YL+ I +
Sbjct: 673 STQLESSLNKYNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQ---KEKHYLQTTITKE 729
Query: 154 SSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQ----------TYEASM 203
A D + ++A D + L VT E +++ + Q+ YE M
Sbjct: 730 --AYDALSRKSAACQDDLTQALEKLNHVTSETKSLQQSLTQTQEKKAQLEEEIIAYEERM 787
Query: 204 DKLREKQRQLEVAQVENQL------LKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQ 257
KL + R+L E++L K++ S Q + + K+ + EE+L+E Q
Sbjct: 788 KKLNTELRKLRGFHQESELEVHAFDKKLEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQ 847
Query: 258 RKHSAEKEALLEE 270
+ +A KE LLE+
Sbjct: 848 EEMAALKENLLED 860
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 68.9 bits (167), Expect = 8e-12
Identities = 75/343 (21%), Positives = 149/343 (43%), Gaps = 52/343 (15%)
Query: 76 VRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQE 135
+ + ++N+QK +V S + E N ++ T+ K + D++ +K+++ TQE
Sbjct: 1935 LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTAL----DQLSEKMKEKTQE 1990
Query: 136 LSVSHAQQ-----EYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDV-------TL 183
L SH + + E ++ ++ L ++ S L D LQ+ L + +L
Sbjct: 1991 LE-SHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSL 2049
Query: 184 ENSNIKDQIRNLQQTYEASMDKLREKQ--------------RQLEVAQVENQLLKMKVES 229
+++QI L + E + + Q + LE A VE +++ S
Sbjct: 2050 TKCELENQIAQLNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSS 2109
Query: 230 SQEANAEVMR---------EMTKKLYSQYEEKLQEEQRKHSA--------EKEALLEETN 272
+QE ++ R E +K EKL+E +R++ + E+E + E N
Sbjct: 2110 TQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLERELQMSEEN 2169
Query: 273 SFLKAIEEANKK--MQAAEISLEE--KDQRIGELDRLIERMEKERHQLQLQLLEHETEMS 328
L ++ N K ++ + +EE + ++ ELD + R EKE Q+Q + +
Sbjct: 2170 QELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKENLTKQIQEKQGQLSEL 2229
Query: 329 GELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMV 371
+L S K ++ E+A ++E + +M+ Q K++ + V
Sbjct: 2230 DKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAV 2272
Score = 58.2 bits (139), Expect = 1e-08
Identities = 84/391 (21%), Positives = 172/391 (43%), Gaps = 50/391 (12%)
Query: 43 EQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMN 102
E+ + ++ KE++L+ E R Q + + + K++ T L +
Sbjct: 323 EKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKLKKL------TEDLSCQRQ 376
Query: 103 YIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNA 162
+ R +LE+ K ++ E + Q+ S QE ++ + + L +
Sbjct: 377 NAESARCSLEQKIKEKEKEFQEELSR-----QQRSFQTLDQECIQMKARL-TQELQQAKN 430
Query: 163 MNSALASDSIGLQKTLVDVTLENS--NIKDQIRNLQQTYEASMDKLREKQRQLEVAQVEN 220
M++ L ++ L T V LEN+ K ++ +Q ++AS K E +R +E + EN
Sbjct: 431 MHNVLQAELDKL--TSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKEN 488
Query: 221 QLLKMKVE--SSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAE-------KEALLEET 271
LLK E + + + E + K+ +Q + +E + K++++ +E + ++
Sbjct: 489 NLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKINQQE 548
Query: 272 NSF----LK-AIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKER----HQLQLQLLE 322
NS LK A+ + K+ ++ L++++ I +L+ + + EKE L+L+ E
Sbjct: 549 NSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKE 608
Query: 323 HETEMSGELT------DSDKERYQQLEEASASLRERIRHLDDMVHCQQKK---------V 367
+E E+ E T +++ Q+E +L+ +I HL+ + QQ K
Sbjct: 609 YE-ELKEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRT 667
Query: 368 KQMVEENNELQSRLDYLTETQAKTEVETREI 398
+M EN ++ R + EVET+++
Sbjct: 668 LEMDRENLSVEIRNLHNVLDSKSVEVETQKL 698
Score = 57.8 bits (138), Expect = 2e-08
Identities = 55/307 (17%), Positives = 134/307 (43%), Gaps = 28/307 (9%)
Query: 107 VRATLEKVRKRMYGDY-----------------DEMRQKIRQLTQELSVSHAQQEYLENH 149
+R ++EK+R R+ D D ++ ++ L +EL ++ QE+
Sbjct: 2299 LRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLKGRVENLERELEIARTNQEHAALE 2358
Query: 150 IQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREK 209
+ ++ A + GL+ +V + E N+ ++++ Q+
Sbjct: 2359 AENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISELEIINSSF 2418
Query: 210 QRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQY--EEKLQEEQRKHSAEKEAL 267
+ L+ + E +K K ++ E ++E+ +++ + + +E + +++ S++ E L
Sbjct: 2419 ENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECL 2478
Query: 268 LEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHETEM 327
E L+ ++EA + S+ Q + + + +E+ ++E +L+ Q+ + E ++
Sbjct: 2479 ELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQE-QL 2537
Query: 328 SGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTET 387
+L+ + E +Q +E + LR L ++K++ + +N LQ L+ L +
Sbjct: 2538 VSKLSQVEGE-HQLWKEQNLELRNLTVEL-------EQKIQVLQSKNASLQDTLEVLQSS 2589
Query: 388 QAKTEVE 394
E E
Sbjct: 2590 YKNLENE 2596
Score = 57.8 bits (138), Expect = 2e-08
Identities = 67/336 (19%), Positives = 146/336 (43%), Gaps = 44/336 (13%)
Query: 75 VVRRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQ 134
+ R +Q Q +E +V SQ++ E K+ L + + ++ K L
Sbjct: 2524 ISRLKNQIQDQEQLVS--KLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQD 2581
Query: 135 ELSVSHAQQEYLENHIQ-TQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQI- 192
L V + + LEN ++ T+ + +N A ++ LQ+ + ++ + + +++++
Sbjct: 2582 TLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKET-ELQREMHEMAQKTAELQEELS 2640
Query: 193 ---RNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQY 249
L + +++++ + QL+ +EN LK ++ + E ++ +++ ++Y
Sbjct: 2641 GEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHKDQVEKEGKVREEI-AEY 2699
Query: 250 EEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERM 309
+ +L E ++KH +ALL +TN ++ ++Q L K++ +
Sbjct: 2700 QLRLHEAEKKH----QALLLDTN------KQYEVEIQTYREKLTSKEECLSS-------- 2741
Query: 310 EKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQ----- 364
+L++ LL+ E EL +S K Q LEE + + +++++ + +
Sbjct: 2742 ----QKLEIDLLKSSKE---ELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGK 2794
Query: 365 -----KKVKQMVEENNELQSRLDYLTETQAKTEVET 395
K KQ+ EE LQ L L Q K + T
Sbjct: 2795 MKLLIKSCKQLEEEKEILQKELSQLQAAQEKQKTGT 2830
Score = 56.6 bits (135), Expect = 4e-08
Identities = 61/311 (19%), Positives = 123/311 (39%), Gaps = 34/311 (10%)
Query: 109 ATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALA 168
A LEK R + I QL +LS + + + L + ++ + + + +
Sbjct: 561 ADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFS 620
Query: 169 SDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVE 228
+K L + E N++ +I +L+ + K E ++ +++ + L +++
Sbjct: 621 CWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDRENLSVEIR 680
Query: 229 SSQEA--NAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQ 286
+ + V E K Y + ++K + +KH E E + +T+ +E+ K+Q
Sbjct: 681 NLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDLEHKLQ 740
Query: 287 AAEISLEEKDQRIGELDRLIERME------------KERHQLQLQLLEHETEMS------ 328
+ +KD+ +L E + E HQ L + + M
Sbjct: 741 LLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAMHHSFANI 800
Query: 329 -GELTDSDKERYQ------QLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQSRL 381
GE ER + Q + SA L+ R+ L+ + Q KQM N++LQ +
Sbjct: 801 IGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQ----KQM---NSDLQKQC 853
Query: 382 DYLTETQAKTE 392
+ L + + + E
Sbjct: 854 EELVQIKGEIE 864
Score = 55.5 bits (132), Expect = 1e-07
Identities = 86/366 (23%), Positives = 167/366 (45%), Gaps = 48/366 (13%)
Query: 96 QLKEEMNYIKDVRAT-LEKVRKR---MYGDYDEMRQKIRQLTQE---LSVSHAQ-----Q 143
Q+KE+ + ++ T L+++ +R ++ D + + K + L+ + L + AQ
Sbjct: 2431 QMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKAQLLQGLD 2490
Query: 144 EYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASM 203
E N+I QSS N + + L+K +++ + I+DQ + + + +
Sbjct: 2491 EAKNNYIVLQSSV----NGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEG 2546
Query: 204 DKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAE 263
+ K++ LE+ + +L + K++ Q NA +++ + L S Y+ L+ E +
Sbjct: 2547 EHQLWKEQNLELRNLTVEL-EQKIQVLQSKNAS-LQDTLEVLQSSYKN-LENELELTKMD 2603
Query: 264 KEALLEETNSFLKAIEEANKKM-----QAAEISLE---EKDQRIGELDRLIERMEKERHQ 315
K + +E+ N E ++M + AE+ E EK++ GEL L+E ++ + Q
Sbjct: 2604 KMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQ 2663
Query: 316 LQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENN 375
L+ LE + EL S ++ E +RE I +H +KK + ++ + N
Sbjct: 2664 LKELTLE-----NSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTN 2718
Query: 376 -----ELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRVLE 430
E+Q+ + LT + + EI DLL S ++E + S T T++LE
Sbjct: 2719 KQYEVEIQTYREKLTSKEECLSSQKLEI----DLLKS----SKEELNNSLKAT--TQILE 2768
Query: 431 LTMKKT 436
+KKT
Sbjct: 2769 -ELKKT 2773
Score = 53.5 bits (127), Expect = 4e-07
Identities = 91/425 (21%), Positives = 178/425 (41%), Gaps = 50/425 (11%)
Query: 22 PSRRANVCRLRLTVPPESPV-----PEQCEKKIERKEQL-LDLSNGEPTRKLPQGVVYGV 75
PS R+ CRL P++ + E +E ++Q+ DL +G +
Sbjct: 808 PSERSE-CRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEEN 866
Query: 76 VRRSDQNQQKEMVVYGWSTSQLKEE----MNYIKDVRATLEKVRKRMYGDYDEMRQKIRQ 131
+ +++Q Q + S+L+E+ N + + + LE K + D++ + +
Sbjct: 867 LMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAE 926
Query: 132 LTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKD- 190
+ QEL S+ E +Q S L S++ S + ++ + ++T EN +K+
Sbjct: 927 I-QELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLN---KREIEELTQENGTLKEI 982
Query: 191 ------QIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKK 244
+ NL Q E+ + + E+++ ++++ +Q + K+ Q E T
Sbjct: 983 NASLNQEKMNLIQKSESFANYIDEREKS--ISELSDQYKQEKLILLQRC------EETGN 1034
Query: 245 LYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDR 304
Y +K + Q K+S + E LL E S + N+ Q E +E + + +L
Sbjct: 1035 AYEDLSQKYKAAQEKNS-KLECLLNECTSLCE--NRKNELEQLKEAFAKEHQEFLTKL-- 1089
Query: 305 LIERMEKERHQ-LQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQ 363
+ER+Q L L+L + + E+TD+ + + L++ I L + +
Sbjct: 1090 ---AFAEERNQNLMLELETVQQALRSEMTDNQNNSKSE----AGGLKQEIMTLKEEQNKM 1142
Query: 364 QKKVKQMVEENNELQSRLDYLTETQ------AKTEVETREIGVG-CDLLPSQTGRTREIV 416
QK+V +++EN +L + E Q + V+ RE C+ P +EI
Sbjct: 1143 QKEVNDLLQENEQLMKVMKTKHECQNLESEPIRNSVKERESERNQCNFKPQMDLEVKEIS 1202
Query: 417 MPSRN 421
+ S N
Sbjct: 1203 LDSYN 1207
Score = 48.1 bits (113), Expect = 2e-05
Identities = 68/368 (18%), Positives = 156/368 (42%), Gaps = 32/368 (8%)
Query: 41 VPEQCEKKIERKEQLLD-LSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKE 99
+P + +KI+ E LD L + R+ + +++ Q + E + LK
Sbjct: 12 LPTRALQKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKT----EGTNLKR 67
Query: 100 EMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDR 159
E + ++ +LEK ++++ + ++ +L+ Q E LE ++ S L+R
Sbjct: 68 ENQRLMEICESLEKTKQKISHELQVKESQVNFQEGQLNSGKKQIEKLEQELKRCKSELER 127
Query: 160 FN--AMNSALASDSIGLQKTLVDVTLENSNIKD--QIRNLQQTYEASMDKLREKQRQLEV 215
A ++ ++ + + + L S + +L++ Y +++ K+ + EV
Sbjct: 128 SQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKYEDLKEKYNKEVEE--RKRLEAEV 185
Query: 216 AQVENQLLKMKVESSQEANAEVMR-EMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSF 274
++ + + + + ++ R + + ++S +EK +S + + S+
Sbjct: 186 KALQAKKASQTLPQATMNHRDIARHQASSSVFSWQQEKTPSHLSSNSQRTPIRRDFSASY 245
Query: 275 LKAIEEANKKMQAAEISLEEKDQRIGE-------LDRLIERMEKERH---QLQLQLLEHE 324
+E +I + + + LD+L + ++ R+ +L+L+L HE
Sbjct: 246 FSGEQEVTPSRSTLQIGKRDANSSFFDNSSSPHLLDQLKAQNQELRNKINELELRLQGHE 305
Query: 325 TEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVK------QMVEENNELQ 378
EM G++ + +E QLE+A L E+ + L+ C+ + V+ Q + L+
Sbjct: 306 KEMKGQV-NKFQELQLQLEKAKVELIEKEKVLN---KCRDELVRTTAQYDQASTKYTALE 361
Query: 379 SRLDYLTE 386
+L LTE
Sbjct: 362 QKLKKLTE 369
Score = 45.8 bits (107), Expect = 8e-05
Identities = 67/329 (20%), Positives = 134/329 (40%), Gaps = 40/329 (12%)
Query: 120 GDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLV 179
G+ M + + E S L+N + + +L+ MNS L L +
Sbjct: 802 GEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKG 861
Query: 180 DVTLEN------------SNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKV 227
++ EN + +I LQ+ A + + E LE + E QLL KV
Sbjct: 862 EIE-ENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKV 920
Query: 228 ESSQEANAEVMR-----EMTKKLYSQYEEKLQEEQRKHSA-------EKEALLEETNSFL 275
E+ Q E+ + E + K E L E+++ S+ E E L +E +
Sbjct: 921 ETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEELTQENGT-- 978
Query: 276 KAIEEANKKMQAAEISLEEKDQR----IGELDRLIERMEKERHQLQLQLLEHETEMSGEL 331
++E N + +++L +K + I E ++ I + + Q +L LL+ E +G
Sbjct: 979 --LKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQ-RCEETGNA 1035
Query: 332 TDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVE----ENNELQSRLDYLTET 387
+ ++Y+ +E ++ L + + ++ +++Q+ E E+ E ++L + E
Sbjct: 1036 YEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEER 1095
Query: 388 QAK--TEVETREIGVGCDLLPSQTGRTRE 414
E+ET + + ++ +Q E
Sbjct: 1096 NQNLMLELETVQQALRSEMTDNQNNSKSE 1124
Score = 43.5 bits (101), Expect = 4e-04
Identities = 48/215 (22%), Positives = 93/215 (43%), Gaps = 29/215 (13%)
Query: 172 IGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQ 231
I L+K + ++ ENS++ +++ ++ E +++E ++ N L+M + S
Sbjct: 1826 IELEKIVGELKKENSDLSEKLEYFSCDHQ-------ELLQRVETSEGLNSDLEMHADKSS 1878
Query: 232 EA----NAEVMREMTKKLYSQYEEKLQE-EQRKHSAEKEALLEETNSFLKAIEEANKKMQ 286
N + + K+ + E +L K S E EAL E + +E +
Sbjct: 1879 REDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIEHEALYLEAD-----LEVVQTEKL 1933
Query: 287 AAEISLEEKDQRIGELDRLIERMEKERHQL--QLQLLEHETEMSGELTDSDKERYQQLEE 344
E E K + I L+ + + ER+QL +L + +T +L++ KE+ Q+LE
Sbjct: 1934 CLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELES 1993
Query: 345 ASASLRERIRHLDDMVHCQQKKVKQMVEENNELQS 379
H + +HC Q ++ E+ LQ+
Sbjct: 1994 ----------HQSECLHCIQVAEAEVKEKTELLQT 2018
Score = 43.1 bits (100), Expect = 5e-04
Identities = 62/275 (22%), Positives = 107/275 (38%), Gaps = 58/275 (21%)
Query: 124 EMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMN------SALASDSIGLQKT 177
++ +R +L S ++E L++ +QT L+ N + S L I ++
Sbjct: 1212 QLEAMLRNKELKLQESEKEKECLQHELQTIRGDLETSNLQDMQSQEISGLKDCEIDAEEK 1271
Query: 178 LVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEV 237
+ E S ++ +LQ + + +M+KL E ++ E+ Q E L ++ S+
Sbjct: 1272 YISGPHELSTSQNDNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITA 1331
Query: 238 MREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQ 297
R+M EE K + +I ++
Sbjct: 1332 TRKMA------------------------------------EEVGKLLNEVKILNDDSGL 1355
Query: 298 RIGELDRLIERME-----KERHQLQLQLLEHETEMSGELTDSDKE---RYQQLEEASASL 349
GEL I E E+H + L L+ E+ LT SDKE + +L+E SL
Sbjct: 1356 LHGELVEDIPGGEFGEQPNEQHPVSLAPLD-ESNSYEHLTLSDKEVQMHFAELQEKFLSL 1414
Query: 350 RERIRHLDDMVHCQQKKVKQMVEENNELQSRLDYL 384
+ + L D HC QM + +ELQ+ +D L
Sbjct: 1415 QSEHKILHDQ-HC------QMSSKMSELQTYVDSL 1442
Score = 40.4 bits (93), Expect = 0.003
Identities = 72/366 (19%), Positives = 145/366 (39%), Gaps = 65/366 (17%)
Query: 39 SPVPEQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLK 98
S V E + K +E+L L L + + + + N++KE++V + Q +
Sbjct: 2021 SDVSELLKDKTHLQEKLQSLEKDSQALSLTKCELENQI--AQLNKEKELLVKESESLQAR 2078
Query: 99 ------EEMNYIKDVRATLEKVRK---RMYGDYDEMRQKIRQLTQELSVSHAQQEYLENH 149
E++N K + A L + + R+ +E+ Q +R+ ++L V E + H
Sbjct: 2079 LSESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQ-LRRGIEKLRVRIEADEKKQLH 2137
Query: 150 IQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDK---- 205
I + +R EN ++KD++ NL++ + S +
Sbjct: 2138 IAEKLKERER------------------------ENDSLKDKVENLERELQMSEENQELV 2173
Query: 206 -LREKQRQLEV----AQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKH 260
L + + EV Q+E +KV E + +R + L Q +
Sbjct: 2174 ILDAENSKAEVETLKTQIEEMARSLKV---FELDLVTLRSEKENLTKQIQ---------- 2220
Query: 261 SAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQL 320
EK+ L E + L + + ++ + AEI ++E+ + E +++ KE ++ L
Sbjct: 2221 --EKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVE---MLQNQLKELNEAVAAL 2275
Query: 321 LEHETEMSG--ELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEENNELQ 378
+ M + D E QL + LR R+ + C +++K+ + L+
Sbjct: 2276 CGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESEHHADLLK 2335
Query: 379 SRLDYL 384
R++ L
Sbjct: 2336 GRVENL 2341
Score = 39.7 bits (91), Expect = 0.005
Identities = 59/336 (17%), Positives = 147/336 (43%), Gaps = 28/336 (8%)
Query: 75 VVRRSDQNQQKEMVVYG-WSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLT 133
V R+S + +++M G +++E + R L+ +RK+ + ++ +QK+ +T
Sbjct: 1558 VYRQSLEKLEEKMESQGIMKNKEIQELEQLLSSERQELDCLRKQYLSENEQWQQKLTSVT 1617
Query: 134 QE----LSVSHAQQEYLENHIQTQSSALDRFNAMNSAL----ASDSIGLQKTLVDVTLEN 185
E L+ Q E L ++ L + + +L D+I + D++ E+
Sbjct: 1618 LEMESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLLGIDTEDAIQGRNESCDISKEH 1677
Query: 186 SNIKDQIRNLQQTYEASMDKLREKQRQLEVAQV-ENQLLKMKVESSQEANAEVMREMTKK 244
++ + R + DK ++ L++ ++ E +K E S E + + E +
Sbjct: 1678 TSETTE-RTPKHDVHQICDKDAQQDLNLDIEKITETGAVKPTGECSGEQSPDTNYEPPGE 1736
Query: 245 LYSQYEEKLQEEQRKHSAEKEALLEET-------NSFLKAIEEANKKMQAAEISLEEKDQ 297
+Q + E ++ N L+ E +N+ ++ + +E++D+
Sbjct: 1737 DKTQGSSECISELSFSGPNALVPMDFLGNQEDIHNLQLRVKETSNENLRLLHV-IEDRDR 1795
Query: 298 RIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLD 357
++ L ++ ++ + H ++QL+ + E EL ++ +L++ ++ L E++ +
Sbjct: 1796 KVESLLNEMKELDSKLHLQEVQLMT-KIEACIEL----EKIVGELKKENSDLSEKLEYFS 1850
Query: 358 DMVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEV 393
C +++ Q VE + L S L+ + ++ ++
Sbjct: 1851 ----CDHQELLQRVETSEGLNSDLEMHADKSSREDI 1882
Score = 39.3 bits (90), Expect = 0.007
Identities = 59/264 (22%), Positives = 112/264 (42%), Gaps = 29/264 (10%)
Query: 92 WSTSQLKE-----EMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYL 146
W+ + KE + I+++ L+K++K E +Q+ QL + Q++ +
Sbjct: 3 WALEEWKEGLPTRALQKIQELEGQLDKLKK-------EKQQRQFQLDSLEAALQKQKQKV 55
Query: 147 ENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKL 206
EN +T+ + L R N L L+KT ++ E +K+ N Q+ +L
Sbjct: 56 ENE-KTEGTNLKR---ENQRLMEICESLEKTKQKISHE-LQVKESQVNFQE------GQL 104
Query: 207 REKQRQLEVAQVENQLLKMKVESSQEA--NAEVMREMTKKLYSQYEEKLQEEQRKHSAEK 264
++Q+E + E + K ++E SQ+A +A+V + L Q ++
Sbjct: 105 NSGKKQIEKLEQELKRCKSELERSQQAAQSADVSLNPCNTPQKIFTTPLTPSQYYSGSKY 164
Query: 265 EALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLEHE 324
E L E+ N K +EE K+++A +L+ K + + RHQ + +
Sbjct: 165 EDLKEKYN---KEVEE-RKRLEAEVKALQAKKASQTLPQATMNHRDIARHQASSSVFSWQ 220
Query: 325 TEMSGELTDSDKERYQQLEEASAS 348
E + S+ +R + SAS
Sbjct: 221 QEKTPSHLSSNSQRTPIRRDFSAS 244
Score = 34.7 bits (78), Expect = 0.18
Identities = 60/275 (21%), Positives = 108/275 (39%), Gaps = 56/275 (20%)
Query: 116 KRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAMNSALASD----- 170
K + + E+++K L E + H Q + + + + +D A N L+++
Sbjct: 1398 KEVQMHFAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLKAENLVLSTNLRNFQ 1457
Query: 171 -------SIGLQKTLVDVTLENSNIKDQIRN------------LQQTYEASMDKLRE--- 208
+GL++ LV +L +S + D L+QT + S+ E
Sbjct: 1458 GDLVKEMQLGLEEGLVP-SLSSSCVPDSSSLSSLGDSSFYRALLEQTGDMSLLSNLEGAV 1516
Query: 209 KQRQLEVAQV------ENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSA 262
Q V +V E L + + S+ E + + + +Y Q EKL+E+
Sbjct: 1517 SANQCSVDEVFCSSLQEENLTRKETPSAPAKGVEELESLCE-VYRQSLEKLEEKMESQGI 1575
Query: 263 EKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQLQLLE 322
K NK++Q E L + Q ELD L ++ E Q Q +L
Sbjct: 1576 MK-----------------NKEIQELEQLLSSERQ---ELDCLRKQYLSENEQWQQKLTS 1615
Query: 323 HETEMSGELTDSDKERYQQLEEASASLRERIRHLD 357
EM +L ++K++ +QL R +++ LD
Sbjct: 1616 VTLEMESKLA-AEKKQTEQLSLELEVARLQLQGLD 1649
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 68.9 bits (167), Expect = 8e-12
Identities = 91/407 (22%), Positives = 175/407 (42%), Gaps = 83/407 (20%)
Query: 52 KEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGW----------STSQLKEEM 101
K+QL DLSN K +G + G++R+ + + Q Y TS+L EE+
Sbjct: 2318 KDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEI 2377
Query: 102 NYIKD-VRATLEKVRKRMYGDYDEMRQ----KIRQLTQELSVSHAQQEYLENHIQ----- 151
N + + + L + + E+RQ +I++L LS + LE +
Sbjct: 2378 NMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDK 2437
Query: 152 ----------------TQSSALDRFNAMNSALASD----------------SIGLQK--T 177
Q + LD F S+L +D SI L+K
Sbjct: 2438 TNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKDQL 2497
Query: 178 LVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVE-----NQLLKMKVESSQE 232
+ + EN+ +K++IR L+ + MD L + +L+ ++ NQ++ +K +S Q+
Sbjct: 2498 IQEAAAENNKLKEEIRGLR----SHMDDLNSENAKLDAELIQYREDLNQVITIK-DSQQK 2552
Query: 233 ANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISL 292
EV + K+L ++Y KL+E+ ++ E L N+ + ++ +K++++ ++S+
Sbjct: 2553 QLLEVQLQQNKELENKY-AKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSI 2611
Query: 293 EEKDQRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRER 352
+ +++ L E + QL++ E E L S ++R +LEE
Sbjct: 2612 SQLTRQVTALQ---EEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEE-------- 2660
Query: 353 IRHLDDMVHCQQKKVKQMVEENNELQSRLDYLTETQA--KTEVETRE 397
++V Q++ K++ E ++L+ L +L + E ET E
Sbjct: 2661 -----ELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAE 2702
Score = 62.8 bits (151), Expect = 6e-10
Identities = 86/369 (23%), Positives = 169/369 (45%), Gaps = 55/369 (14%)
Query: 79 SDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSV 138
S+ ++K+ +V + + + Y++ ++ ++ + + E+++ +++ QE V
Sbjct: 1966 SELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAK--ELQELLKEKQQE--V 2021
Query: 139 SHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQT 198
Q++ + Q + SAL+R + ++S QK L ++T EN + R Q
Sbjct: 2022 KQLQKDCIR--YQEKISALERTVKALEFVQTES---QKDL-EITKENLAQAVEHRKKAQA 2075
Query: 199 YEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
AS L + Q E A+V LK+K E ++N E ++ K+ E +L++ +
Sbjct: 2076 ELASFKVLLD-DTQSEAARVLADNLKLKKEL--QSNKESVKSQMKQKDEDLERRLEQAEE 2132
Query: 259 KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQLQL 318
KH EK+ + E+ ++ ++ ++ LEE IGE+ + + +KE QLQ
Sbjct: 2133 KHLKEKKNMQEKLDA-----------LRREKVHLEE---TIGEIQVTLNKKDKEVQQLQE 2178
Query: 319 QLLEHETEMSG-------------ELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQK 365
L T+++ + D K+ ++ +A S E IR +D +
Sbjct: 2179 NLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLKEDNCSVLKD 2238
Query: 366 KVKQMVEENNELQ---SRLDY---LTETQAKTEVETREIGVGCDLLP-------SQTGRT 412
+++QM EL+ SRL++ + E++A+TEV+ ++ CD L SQ T
Sbjct: 2239 QLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQ--KVCDTLQGENKELLSQLEET 2296
Query: 413 REIVMPSRN 421
R + S+N
Sbjct: 2297 RHLYHSSQN 2305
Score = 59.7 bits (143), Expect = 5e-09
Identities = 70/391 (17%), Positives = 171/391 (43%), Gaps = 53/391 (13%)
Query: 43 EQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGW---------- 92
++ EK+++ EQ ++ E RK + ++ ++N + V+
Sbjct: 1658 KETEKQLQEAEQEMEEMK-EKMRKFAKSKQQKILELEEENDRLRAEVHPAGDTAKECMET 1716
Query: 93 ---STSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLE-- 147
S + +KEE+ +K TL K + + + D + ++++ L ++ + ++Q LE
Sbjct: 1717 LLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNVSKQANLEAT 1776
Query: 148 --------------NHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIR 193
I ++ D + S+S+ K+ ++ + D+I
Sbjct: 1777 EKHDNQTNVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEIN 1836
Query: 194 NLQQTYEASMDKL----REKQRQLEVAQ-VENQLLKMKVE-SSQEANAEVMREMTKKLYS 247
N Q + +++ EKQ+ E +Q +EN+ + + S+++ ++++E K+ +
Sbjct: 1837 NYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQEEVTKM-N 1895
Query: 248 QYEEKLQEEQRKHSAEKEALLEETNSF----LKAIEEAN-------KKMQAAEISLEEKD 296
+++QEE + + KE EE + + + E N + + A+I E +
Sbjct: 1896 LLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLE 1955
Query: 297 QRIGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHL 356
+ L + + +E+E+ QL++ +T++ E+ E+ Q ++ + + + L
Sbjct: 1956 SEMKNLKKCVSELEEEKQ----QLVKEKTKVESEIRKEYLEKIQGAQKEPGN-KSHAKEL 2010
Query: 357 DDMVHCQQKKVKQMVEENNELQSRLDYLTET 387
+++ +Q++VKQ+ ++ Q ++ L T
Sbjct: 2011 QELLKEKQQEVKQLQKDCIRYQEKISALERT 2041
Score = 58.2 bits (139), Expect = 1e-08
Identities = 61/297 (20%), Positives = 134/297 (45%), Gaps = 55/297 (18%)
Query: 77 RRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQEL 136
R+S++ +Q+ S E+ +K ++L+ R R+ + ++Q+ Q+ QE+
Sbjct: 2856 RKSEEGKQRSAA----QPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEI 2911
Query: 137 SVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQ 196
+ H + L+ + Q ++ A F M L +++ Q L + +E S+ + R ++
Sbjct: 2912 TELHPLKAQLQEY-QDKTKA---FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMK 2967
Query: 197 QTYEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEE 256
+ Y + + +K +QL + ++N + +++ SSQ T+ L QY+ + E
Sbjct: 2968 EQY---LMAISDKDQQL--SHLQNLIRELRSSSSQ----------TQPLKVQYQRQASPE 3012
Query: 257 QRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEKERHQL 316
+ L+ ET + ++ K+ + +K+ RI +L+ ++ +E++ L
Sbjct: 3013 TSASPDGSQNLVYETELLRTQLNDSLKE-------IHQKELRIQQLNSNFSQLLEEKNTL 3065
Query: 317 QLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMV-HCQ--QKKVKQM 370
+QL + S SLRE +H D++ HC +K+V+++
Sbjct: 3066 SIQLCD----------------------TSQSLRENQQHYGDLLNHCAVLEKQVQEL 3100
Score = 57.8 bits (138), Expect = 2e-08
Identities = 80/367 (21%), Positives = 150/367 (40%), Gaps = 40/367 (10%)
Query: 79 SDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSV 138
S Q +KE + T +++E + IK + LE K ++DE +I+QL EL
Sbjct: 1412 SGQLSEKEAALTKIQTEIIEQE-DLIKALHTQLEMQAK----EHDE---RIKQLQVELCE 1463
Query: 139 SHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQT 198
+ E + + + + A AL S L+ EN ++++++ + T
Sbjct: 1464 MKQKPEEIGEESRAKQQIQRKLQA---ALISRKEALK--------ENKSLQEELSLARGT 1512
Query: 199 YEASMDKLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQR 258
E L + + Q+ E + ++ QE +++ EM + L + L
Sbjct: 1513 IERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLEN--QSLSSSCE 1570
Query: 259 KHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG-ELDRLIERMEK-----E 312
E L E+ +K IE A +EK + + E + L++ E E
Sbjct: 1571 SLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAE 1630
Query: 313 RHQLQLQLLEHET-EMSGELTDSD---KERYQQLEEASASLRERIRHLDDMVHCQQKKVK 368
R Q ++ + E E+ G+L ++ KE +QL+EA + E + +Q+K+
Sbjct: 1631 RIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKIL 1690
Query: 369 QMVEENNELQSRLDYLTETQAKTEVETREIGVGCDLLPSQTGRTREIVMPSRNYTPYTRV 428
++ EEN+ L++ + +T AK +ET LL S E+ Y ++
Sbjct: 1691 ELEEENDRLRAEVHPAGDT-AKECMET--------LLSSNASMKEELERVKMEYETLSKK 1741
Query: 429 LELTMKK 435
+ M +
Sbjct: 1742 FQSLMSE 1748
Score = 57.8 bits (138), Expect = 2e-08
Identities = 71/336 (21%), Positives = 141/336 (41%), Gaps = 65/336 (19%)
Query: 98 KEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSV--SHAQQEYLENHIQTQSS 155
+EE+ +D + L+ ++M +E++ I +L + + S AQ E +Q Q
Sbjct: 2223 EEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTE-----VQLQQK 2277
Query: 156 ALDRFNAMNSALASDSI-------GLQKTLVDVTLENSNIKDQIRNLQQTYEASMDK--- 205
D N L S Q L + E ++KDQ+ +L + E ++
Sbjct: 2278 VCDTLQGENKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCKEQKGN 2337
Query: 206 ----LREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKK----------------- 244
+R+++ ++ ++ + L+ +++S+E + + E+ K
Sbjct: 2338 LEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQV 2397
Query: 245 ----LYSQYEEKLQEEQRKHSAEKEA--LLEETNSFLKAIEEANKKMQAAEISLEEKDQR 298
L Q++++++E + S E+E +LEE N KA+++ N+ M+ + +E Q+
Sbjct: 2398 AIAELRQQHDKEIKELENLLSQEEEENIVLEEENK--KAVDKTNQLMETLKTIKKENIQQ 2455
Query: 299 IGELDRLIERMEKERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDD 358
+LD ++ M L + G+ YQQLEE S+ I D
Sbjct: 2456 KAQLDSFVKSMS--------SLQNDRDRIVGD--------YQQLEERHLSI---ILEKDQ 2496
Query: 359 MVHCQQKKVKQMVEENNELQSRLDYLTETQAKTEVE 394
++ + ++ EE L+S +D L AK + E
Sbjct: 2497 LIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE 2532
Score = 54.3 bits (129), Expect = 2e-07
Identities = 72/336 (21%), Positives = 141/336 (41%), Gaps = 48/336 (14%)
Query: 95 SQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQS 154
S + E +K + L + ++ DY+ LT+++ + + + I+
Sbjct: 757 SMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQ 816
Query: 155 SALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLE 214
+ LD S ++ LQ L + E +++R++ E L Q++LE
Sbjct: 817 NELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQAL--SQKELE 874
Query: 215 VAQVENQLLKMK---------VESSQEANAEVMREMTKKLYSQYEEK---------LQEE 256
+ +++ LL+ K +E + E+ MT+K+ EEK L+E+
Sbjct: 875 ITKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQ 934
Query: 257 ----QRKHSAEKEALLEETNSFLKAIEEANKKMQ-AAEISLEEKDQRIGELDRLIERMEK 311
R A+KE +EE N +++ +M A +IS EE E D L + E+
Sbjct: 935 LNLLSRAEEAKKEQ-VEEDNEVSSGLKQNYDEMSPAGQISKEELQH---EFDLLKKENEQ 990
Query: 312 ERHQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMV 371
+ +LQ L+ + + +R +LEE A+L++ + + ++ +V++
Sbjct: 991 RKRKLQAALINRKELL---------QRVSRLEEELANLKDESKKEIPLSETERGEVEE-D 1040
Query: 372 EENNELQSRL---------DYLTETQAKTEVETREI 398
+EN E + YL +T ++ EVE + I
Sbjct: 1041 KENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHI 1076
Score = 50.8 bits (120), Expect = 2e-06
Identities = 66/362 (18%), Positives = 150/362 (41%), Gaps = 49/362 (13%)
Query: 44 QCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMNY 103
+ + +++ ++++ D GE L Q + S QN+ ++L+ E+
Sbjct: 2267 KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHSSQNE----------LAKLESELKS 2316
Query: 104 IKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSVSHAQQEYLENHIQTQSSALDRFNAM 163
+KD L ++ + IRQ ++ S E LE +Q R +
Sbjct: 2317 LKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE- 2375
Query: 164 NSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLREKQRQLEVAQVENQLL 223
++ ++ I + ++ + ++ +LR+ Q E+ ++EN L
Sbjct: 2376 ----------------EINMKEQKIISLLSGKEEAIQVAIAELRQ-QHDKEIKELENLL- 2417
Query: 224 KMKVESSQEANAEVMREMTKKLYSQYEEKLQ--EEQRKHSAEKEALLEETNSFLKAIEEA 281
S +E V+ E KK + + ++ + +K + +++A L+ + +++
Sbjct: 2418 -----SQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQND 2472
Query: 282 NKKMQAAEISLEEKD-QRIGELDRLIERMEKERHQLQLQ---LLEHETEMSGELTDSDKE 337
++ LEE+ I E D+LI+ E ++L+ + L H +++ E D E
Sbjct: 2473 RDRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE 2532
Query: 338 RYQQLEEASASLRERIRHLDDMVHCQQKKVKQM-VEENNELQSRLDYLTETQAKTEVETR 396
Q RE + + + QQK++ ++ +++N EL+++ L E ++E
Sbjct: 2533 LIQ--------YREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANE 2584
Query: 397 EI 398
++
Sbjct: 2585 DL 2586
Score = 49.3 bits (116), Expect = 7e-06
Identities = 81/371 (21%), Positives = 159/371 (42%), Gaps = 63/371 (16%)
Query: 83 QQKEMV-VYGWSTSQLKEEMNYIKDVRAT---LEKVRKRMYGDYDEMRQKIRQLTQE--- 135
Q KE+ Y +LKE +D+R + L++ ++ + + + ++ I QLT++
Sbjct: 2561 QNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTA 2620
Query: 136 ------LSVSHAQQEYLENHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLE-NSNI 188
L + HAQ + E + S+ + L + + +QK E +
Sbjct: 2621 LQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKL 2680
Query: 189 KDQIRNL---------------QQTYEASMDKLREKQRQLEVAQVENQLLKMKVES---- 229
K ++++L ++ E + D + +Q+ L V + EN+ L +++S
Sbjct: 2681 KKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTK-ENKGLTAQIQSFGRS 2739
Query: 230 ------SQEANAEVMREMTKKLYSQYEEKLQ-EEQRKHSAEKEALLEETNSFLKAIEE-- 280
S++ E + E+ +K + +E Q +EQ + E++ALL ET + + EE
Sbjct: 2740 MSSLQNSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENS 2799
Query: 281 -----------ANKKMQAAEIS--LEEKDQRIGELDRLIERMEKERHQLQLQL-----LE 322
+K Q +S LE+ ++ + + ++ ER L +L E
Sbjct: 2800 LSHLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE 2859
Query: 323 HETEMSGELTDSDKERYQQLEEASASLR-ERIRHLDDMVHCQQKKVKQMVEENNELQSRL 381
+ S + Q L++A +SL+ +R R L ++ + QQ+ + Q+ +E EL
Sbjct: 2860 EGKQRSAAQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYL-QINQEITELHPLK 2918
Query: 382 DYLTETQAKTE 392
L E Q KT+
Sbjct: 2919 AQLQEYQDKTK 2929
Score = 46.2 bits (108), Expect = 6e-05
Identities = 73/321 (22%), Positives = 129/321 (40%), Gaps = 68/321 (21%)
Query: 124 EMRQKIRQLTQELS-VSHAQQEYLENHIQTQSSALDRFNAMNSALAS---DSIGLQKTLV 179
E+ +KI L +E + QE L + A ++ + L D LQ+
Sbjct: 1161 ELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFD 1220
Query: 180 DVTLENSNIKDQIRNLQQTYEASMD-KLREKQRQ-------------------------- 212
+ + EN NI DQ+R LQ S+D KL +Q
Sbjct: 1221 EQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVL 1280
Query: 213 ---------------------LEVAQVENQLLKMKVE--SSQEANAEVMREMTKKLYSQY 249
VAQ++ QL +++ E + + E+TKK S+
Sbjct: 1281 ESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSSTTSELTKK--SEE 1338
Query: 250 EEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEIS------LEEKDQRIGELD 303
+LQE+ K E E+L ++ E +K++++++ L E ++ EL
Sbjct: 1339 VFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQ 1398
Query: 304 RLIERMEKERHQLQLQLLEHE---TEMSGELTDSD---KERYQQLEEASASLRERIRHLD 357
+LI + E++ L QL E E T++ E+ + + K + QLE + ERI+ L
Sbjct: 1399 KLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQ 1458
Query: 358 DMVHCQQKKVKQMVEENNELQ 378
+ ++K +++ EE+ Q
Sbjct: 1459 VELCEMKQKPEEIGEESRAKQ 1479
Score = 42.4 bits (98), Expect = 8e-04
Identities = 69/347 (19%), Positives = 146/347 (42%), Gaps = 41/347 (11%)
Query: 77 RRSDQNQQKEMVVYGWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQEL 136
R++ N+ K++ ++ + ++L YI++++A V +++ + + T+E
Sbjct: 86 RKAADNKIKKLKLH--AKAKLTSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEE 143
Query: 137 ----SVSHAQQEYLENHIQTQSSALDRFNAMNSALAS----DSIGLQKTLVDVTLENSNI 188
+ H QE E I T + L + A A +S + + +++ L + S +
Sbjct: 144 MEIEKIKHKLQEK-EELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKEEFISTL 202
Query: 189 KDQIRNLQQTYEASMDKLREKQRQLE--VAQVENQLLKMKVESSQEANAEVMREMTKKLY 246
+ Q+ Q +A+ +REK + E V E++LL++ ++ E
Sbjct: 203 QAQLSQTQAE-QAAQQVVREKDARFETQVRLHEDELLQLVTQADVE-------------- 247
Query: 247 SQYEEKLQEEQRKHSAEKEALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLI 306
++ ++KL+ QRK +E+L+ +E Q +I ++ Q E + L
Sbjct: 248 TEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLR 307
Query: 307 ERMEKERHQLQLQLLEHETEMSGELTDSDK---------ERYQQLEEASASLRERIRHLD 357
+E ER + ++ L + E E++ E+++Q +A A L R L+
Sbjct: 308 NTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALE 367
Query: 358 DMVHCQQKK----VKQMVEENNELQSRLDYLTETQAKTEVETREIGV 400
+ ++ + + + ELQS D L + +K + E V
Sbjct: 368 QKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAV 414
Score = 39.3 bits (90), Expect = 0.007
Identities = 71/387 (18%), Positives = 145/387 (37%), Gaps = 67/387 (17%)
Query: 43 EQCEKKIERKEQLLDLSNGEPTRKLPQGVVYGVVRRSDQNQQKEMVVYGWSTSQLKEEMN 102
E ++ IE K+Q + + T K+ Q +E G LKE++N
Sbjct: 890 ETLQQTIEEKDQQVTEISFSMTEKMVQ-------------LNEEKFSLGVEIKTLKEQLN 936
Query: 103 YIKDVRATLEK-------VRKRMYGDYDEMRQ----KIRQLTQELSVSHAQQEYLENHIQ 151
+ ++ V + +YDEM +L E + + E + +Q
Sbjct: 937 LLSRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQ 996
Query: 152 T----QSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMDKLR 207
+ L R + + LA+ +K + E +++ N + + + K +
Sbjct: 997 AALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQ 1056
Query: 208 EKQRQLE--VAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEKE 265
E + L+ +++ E +L ++ + ++ AE E + L Q + LQ++ + +
Sbjct: 1057 EIEIYLKQTISEKEVELQHIRKDLEEKLAAE---EQFQALVKQMNQTLQDKTNQIDLLQA 1113
Query: 266 ALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIG------------ELDRLIERMEKER 313
+ E K I ++L ++ I EL+ I +EKE+
Sbjct: 1114 EISENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEK 1173
Query: 314 HQLQLQLLEHETEMSGELTDSDKERYQQLEEASASLRERIRHLDDMVHCQQKKVKQMVEE 373
QLQ +L E T L + +E+ RHL ++++KQ ++
Sbjct: 1174 EQLQKKLQEALTSRKAILKKA---------------QEKERHL-------REELKQQKDD 1211
Query: 374 NNELQSRLDYLTETQAKTEVETREIGV 400
N LQ + D ++ + R++ +
Sbjct: 1212 YNRLQEQFDEQSKENENIGDQLRQLQI 1238
Score = 32.7 bits (73), Expect = 0.67
Identities = 68/319 (21%), Positives = 126/319 (39%), Gaps = 45/319 (14%)
Query: 94 TSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQLTQELSV-----SHAQQEYLEN 148
T + E++ I V ++ D + Q +ELSV AQ+E
Sbjct: 517 TGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVLLLEMKEAQEEIAFL 576
Query: 149 HIQTQSSALDRFNA----MNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQQTYEASMD 204
+Q Q + + + G+ + V LE++ Q L E+S+
Sbjct: 577 KLQLQGKRAEEADHEVLDQKEMKQMEGEGIAPIKMKVFLEDTG---QDFPLMPNEESSLP 633
Query: 205 KLREKQRQLEVAQVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK 264
+ ++Q A E+Q + S +A E+ + TK+ + + + + H E
Sbjct: 634 AVEKEQ-----ASTEHQSRTSEEISLNDAGVEL--KSTKQDGDKSLSAVPDIGQCHQDEL 686
Query: 265 EALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLIERMEK------------- 311
E L + L+ +K + E +L+EK + I L++LIE +K
Sbjct: 687 ERLKSQ---ILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALS 743
Query: 312 -ERHQL--QLQLLEHETEMSG-----ELTDSDKERYQQLEEASASLRERIRHLDDMVHCQ 363
ER QL Q++ L TE+ E+ ++ ER ++L+ S + + + L + +H
Sbjct: 744 EERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNL--LTEQIHSL 801
Query: 364 QKKVKQMVEENNELQSRLD 382
+ K + LQ+ LD
Sbjct: 802 SIEAKSKDVKIEVLQNELD 820
Score = 32.0 bits (71), Expect = 1.1
Identities = 48/237 (20%), Positives = 101/237 (42%), Gaps = 31/237 (13%)
Query: 98 KEEMNYIKDVRATLEKVRKRMYGDY-------DEMRQKIRQLTQELSVSHAQQEYLENHI 150
+ E++ ++ +++ E +RM Y D+ ++ L +EL S +Q + L+
Sbjct: 2946 QHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLIRELRSSSSQTQPLKVQY 3005
Query: 151 QTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKD-QIRNLQQTYEASMDK---- 205
Q Q+S + S L +T ++ +L+ + K+ +I+ L + +++
Sbjct: 3006 QRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRIQQLNSNFSQLLEEKNTL 3065
Query: 206 ----------LREKQRQLEVAQVENQLLKMKVESSQEA--NAEVMREMTKKLYSQYE--- 250
LRE Q+ +L+ +V+ Q N +V ++ +
Sbjct: 3066 SIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAGPLNIDVAPGAPQEKNGVHRKSD 3125
Query: 251 -EKLQEEQRKHSAEKEALL---EETNSFLKAIEEANKKMQAAEISLEEKDQRIGELD 303
E+L+E Q+ S ++ L +E N K +EE + AAE +L +++I L+
Sbjct: 3126 PEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSVAEEQIRRLE 3182
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.125 0.327
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,677,198
Number of Sequences: 37866
Number of extensions: 688555
Number of successful extensions: 11992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 446
Number of HSP's successfully gapped in prelim test: 1150
Number of HSP's that attempted gapping in prelim test: 4590
Number of HSP's gapped (non-prelim): 4549
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.