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Search of human proteins with 11141903
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11141903 FAST kinase domains 5 [Homo sapiens]
(764 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11141903 FAST kinase domains 5 [Homo sapiens] 1531 0.0
gi|188497683 FAST kinase domains 1 [Homo sapiens] 70 7e-12
gi|40068497 FAST kinase domains 3 [Homo sapiens] 69 2e-11
gi|209969832 FAST kinase domains 2 [Homo sapiens] 57 5e-08
gi|209969830 FAST kinase domains 2 [Homo sapiens] 57 5e-08
gi|45267832 FAST kinase domains 2 [Homo sapiens] 57 5e-08
gi|40217812 cell cycle progression 2 protein isoform 1 [Homo sap... 51 5e-06
gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo... 50 8e-06
gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Hom... 50 8e-06
gi|40217810 cell cycle progression 2 protein isoform 2 [Homo sap... 37 0.069
gi|13569848 cell cycle progression 2 protein isoform 2 [Homo sap... 37 0.069
gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens] 33 1.3
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 32 1.7
gi|4505683 platelet-derived growth factor receptor beta precurso... 31 3.8
gi|4506671 ribosomal protein P2 [Homo sapiens] 31 4.9
gi|122937345 myosin VB [Homo sapiens] 30 6.4
gi|46195755 SCAN domain containing 3 [Homo sapiens] 30 8.4
>gi|11141903 FAST kinase domains 5 [Homo sapiens]
Length = 764
Score = 1531 bits (3964), Expect = 0.0
Identities = 764/764 (100%), Positives = 764/764 (100%)
Query: 1 MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNIC 60
MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNIC
Sbjct: 1 MAATLKSLKLVRYRAFCSPSAFGAVRSVSYWNVSSTQHGGQDPPEHISLCHSAKKVKNIC 60
Query: 61 STFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQ 120
STFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQ
Sbjct: 61 STFSSRRILTTSSAHPGLEFSKTSSSKASTLQLGSPRATGVDEEDVEVFDSFENMRVFLQ 120
Query: 121 LRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPV 180
LRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPV
Sbjct: 121 LRPEYRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPV 180
Query: 181 LLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMN 240
LLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMN
Sbjct: 181 LLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMN 240
Query: 241 MDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQ 300
MDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQ
Sbjct: 241 MDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQVSQDLMQ 300
Query: 301 KLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIV 360
KLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIV
Sbjct: 301 KLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSRSLVNIV 360
Query: 361 KMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPP 420
KMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPP
Sbjct: 361 KMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPP 420
Query: 421 RVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLA 480
RVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLA
Sbjct: 421 RVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLA 480
Query: 481 FLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQE 540
FLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQE
Sbjct: 481 FLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDYRGNRLSTHLQQE 540
Query: 541 GSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKP 600
GSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKP
Sbjct: 541 GSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDLEVQLDVNLKP 600
Query: 601 LPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENK 660
LPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENK
Sbjct: 601 LPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENK 660
Query: 661 AAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNM 720
AAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNM
Sbjct: 661 AAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNM 720
Query: 721 KRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL 764
KRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL
Sbjct: 721 KRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVFTSAL 764
>gi|188497683 FAST kinase domains 1 [Homo sapiens]
Length = 847
Score = 70.1 bits (170), Expect = 7e-12
Identities = 89/403 (22%), Positives = 159/403 (39%), Gaps = 100/403 (24%)
Query: 368 VDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRS 427
+D IN++ +GEIA + S+ +L+ +++ +A+ ++
Sbjct: 528 MDDINYIN-VGEIAS----------------FISSTDYLSTLLLDRIASVAVQQIEKIHP 570
Query: 428 KDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPV 487
+ I+ F LNY PP +EF + + ++ + + P L LA LEYFP
Sbjct: 571 FTIPAIIRPFSVLNYDPPQRDEFLGTCVQHLNSYLGILD--PFILVFLGFSLATLEYFPE 628
Query: 488 ELIDFALSPGFVRLAQERTKFDLLK---------ELYTLDGTVGIECPDYRGNRLSTHLQ 538
+L+ + F LA+ ++ ++L L L+ +V +ECP+++
Sbjct: 629 DLLKAIFNIKF--LARLDSQLEILSPSRSARVQFHLMELNRSVCLECPEFQIPWFHDRFC 686
Query: 539 QEGSELLWYLAEKDMNSKPEFLETVF-LLETMLGGPQYVKHHMILPHTRSSDLEVQLDVN 597
Q+ + K + + +F +L +LGG VK ++ P+ D E LD
Sbjct: 687 QQYN--------KGIGGMDGTQQQIFKMLAEVLGGINCVKASVLTPYYHKVDFECILDKR 738
Query: 598 LKPLPFNREATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMEL 657
KPLP+ + N+A +L + +++ L PG + + L
Sbjct: 739 KKPLPYG-----SHNIALGQLPEMPWESNIEIVGSRL--------------PPGAERIAL 779
Query: 658 ENKAAVPLGGFLCNVADKSGAMEMAGLCPAACMQTPRMKLAVQFTNRNQYCYGSRDLLGL 717
E FL + A C P MK G
Sbjct: 780 E---------FLDS--------------KALCRNIPHMK-------------------GK 797
Query: 718 HNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKVF 760
MK+R L LGYRV+++S +EW + T+ ++ +L E +F
Sbjct: 798 SAMKKRHLEILGYRVIQISQFEWNSMALSTKDARMDYLRECIF 840
Score = 33.9 bits (76), Expect = 0.58
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 35/166 (21%)
Query: 246 LVADLWRYLGRKVPRFLNIFSSYL---NLHWKDL--SLSQLVHLIYVIGENRQVSQDL-- 298
LV + WR L R + L+ FSS L +L++ L ++ +VH N + +QDL
Sbjct: 139 LVTEAWRRLERFDIKLLSEFSSCLADQHLYFSPLMGKIADIVH------RNLETTQDLSS 192
Query: 299 ----MQKLESLILKYID--LINLEEV--GTICLGFFKSSTNLSEFV----------MRKI 340
M + SLI ++ L+N E+ TI + ++++F+ + +
Sbjct: 193 LSVLMVNISSLISRHFQQQLVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQPLLERC 252
Query: 341 GDLACANIQHLSSRSLVNIVKMFRFTHVDHINFM----KQIGEIAP 382
++ +N+ HL S+ I+ +++F + F+ K++ E+ P
Sbjct: 253 NNVFLSNVDHLDLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIP 298
>gi|40068497 FAST kinase domains 3 [Homo sapiens]
Length = 662
Score = 68.9 bits (167), Expect = 2e-11
Identities = 83/425 (19%), Positives = 172/425 (40%), Gaps = 14/425 (3%)
Query: 181 LLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHSHSMLDVYETKCCHQVWEMN 240
+L ++ F LC K+ L+ L+A ++L + S+L +C +++ +
Sbjct: 153 ILENSIFQALCFQFEKEPSQLSNTSLVTALQALILLHVDPQSSLLLNLVAECQNRLRKGG 212
Query: 241 MD--QLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDL----SLSQLVHLIYVIGENRQV 294
M+ L ++ + L L + + L + + L ++ E
Sbjct: 213 MEVRNLCILGESLITLHSSGCVTLELIINQLQGEKLETFTPEDIVALYRILQACTEKVDE 272
Query: 295 SQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQHLSSR 354
Q + K+ + L + ++ + + + + + ++ K+G ++ H ++
Sbjct: 273 HQTFLNKINNFSLSIVSNLSPKLISQMLTALVVLDQSQAFPLIIKLGKYVVRHVPHFTNE 332
Query: 355 SLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGVMNAV 414
L +++ F + F K + +L + V + YCS L++ ++NAV
Sbjct: 333 ELRRVLEAFIYFGHHDTFFTKALEHRVAAVCLTLDPEVVCRVMEYCSRELILSKPILNAV 392
Query: 415 AASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQY-PEHLP 473
A + + + ++ ++ FG LNY PPNA + L + + FN + P+ L
Sbjct: 393 AETFVCQTEKFSPRQISALMEPFGKLNYLPPNASALFRKLENVL---FTHFNYFPPKSLL 449
Query: 474 TCLLGLAFLEYFPVELIDFALSPGFV-RLAQERTKFDLLK--ELYTLDGTVGIECPDYRG 530
L + E PV + P F+ RL + + D L +L L +ECP Y+G
Sbjct: 450 KLLHSCSLNECHPVNFLAKIFKPLFLQRLQGKESHLDTLSRAQLTQLFLASVLECPFYKG 509
Query: 531 NRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETMLGGPQYVKHHMILPHTRSSDL 590
+L Q + E ++S+ + L +LG Y ++ P+ + D+
Sbjct: 510 PKLLPKYQVKSFLTPCCSLETPVDSQ-LYRYVKIGLTNLLGARLYFAPKVLTPYCYTIDV 568
Query: 591 EVQLD 595
E++LD
Sbjct: 569 EIKLD 573
Score = 42.4 bits (98), Expect = 0.002
Identities = 24/76 (31%), Positives = 44/76 (57%), Gaps = 2/76 (2%)
Query: 686 PAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLK 745
P+ + ++A+ ++C S+ LLG +K+R L LGY+VV++ Y E + +LK
Sbjct: 580 PSTANEDIHKRIALCIDGPKRFCSNSKHLLGKEAIKQRHLQLLGYQVVQIPYHE-IGMLK 638
Query: 746 RTRLEKLAFLHEKVFT 761
+R E + +L K+F+
Sbjct: 639 -SRRELVEYLQRKLFS 653
>gi|209969832 FAST kinase domains 2 [Homo sapiens]
Length = 710
Score = 57.4 bits (137), Expect = 5e-08
Identities = 86/435 (19%), Positives = 182/435 (41%), Gaps = 44/435 (10%)
Query: 180 VLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHS----HSMLDVYETKC--C 233
++ +F LC+ +++ ++ + L+ L A V LGIP + ++L V + + C
Sbjct: 206 LMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVTQERINEC 265
Query: 234 HQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQ 293
++ + +L + + + F + + WK + L ++ IG++
Sbjct: 266 DEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQV---WKIEDVFTLQVVMKCIGKDAP 322
Query: 294 VSQDLMQKLESLILKYID---LINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQH 350
++ L +KLE L+ +D ++N + + + S L + + + D NI
Sbjct: 323 IA--LKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLD----NIHG 376
Query: 351 LSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGV 410
R ++NI++ + +++ K + + + V+ + + L F G+
Sbjct: 377 CPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGL 436
Query: 411 MNAVAASLPPRVAHCRSKDVAKILWSFGTLN--YKPPNAEEFYSSLISEIHRKMPEFNQY 468
M+ + K++ IL ++ +LN YK N E+F + S + + +
Sbjct: 437 MDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISS- 495
Query: 469 PEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDY 528
E+L + + YFP L+P F +L Q+ D++ EL T D Y
Sbjct: 496 -ENLLDAVYSFCLMNYFP-------LAP-FNQLLQK----DIISELLTSDDMKNA----Y 538
Query: 529 RGNRLSTHLQQEGSELLWYLA------EKDMNSKPEFLETVFLLETMLGGPQYVKHHMIL 582
+ + L T L+ + + L +A +++ S + +L ++LGG + + L
Sbjct: 539 KLHTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHL 598
Query: 583 PHTRSSDLEVQLDVN 597
PH D E+++D N
Sbjct: 599 PHNYHIDFEIRMDTN 613
Score = 36.6 bits (83), Expect = 0.090
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 692 TPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEK 751
T ++AV +R+ YC GS G MK R L +G+ V+ ++ WE + K +
Sbjct: 629 TDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWE---MDKLEMEDA 685
Query: 752 LAFLHEKVFT 761
+ FL K+++
Sbjct: 686 VTFLKTKIYS 695
>gi|209969830 FAST kinase domains 2 [Homo sapiens]
Length = 710
Score = 57.4 bits (137), Expect = 5e-08
Identities = 86/435 (19%), Positives = 182/435 (41%), Gaps = 44/435 (10%)
Query: 180 VLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHS----HSMLDVYETKC--C 233
++ +F LC+ +++ ++ + L+ L A V LGIP + ++L V + + C
Sbjct: 206 LMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVTQERINEC 265
Query: 234 HQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQ 293
++ + +L + + + F + + WK + L ++ IG++
Sbjct: 266 DEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQV---WKIEDVFTLQVVMKCIGKDAP 322
Query: 294 VSQDLMQKLESLILKYID---LINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQH 350
++ L +KLE L+ +D ++N + + + S L + + + D NI
Sbjct: 323 IA--LKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLD----NIHG 376
Query: 351 LSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGV 410
R ++NI++ + +++ K + + + V+ + + L F G+
Sbjct: 377 CPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGL 436
Query: 411 MNAVAASLPPRVAHCRSKDVAKILWSFGTLN--YKPPNAEEFYSSLISEIHRKMPEFNQY 468
M+ + K++ IL ++ +LN YK N E+F + S + + +
Sbjct: 437 MDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISS- 495
Query: 469 PEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDY 528
E+L + + YFP L+P F +L Q+ D++ EL T D Y
Sbjct: 496 -ENLLDAVYSFCLMNYFP-------LAP-FNQLLQK----DIISELLTSDDMKNA----Y 538
Query: 529 RGNRLSTHLQQEGSELLWYLA------EKDMNSKPEFLETVFLLETMLGGPQYVKHHMIL 582
+ + L T L+ + + L +A +++ S + +L ++LGG + + L
Sbjct: 539 KLHTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHL 598
Query: 583 PHTRSSDLEVQLDVN 597
PH D E+++D N
Sbjct: 599 PHNYHIDFEIRMDTN 613
Score = 36.6 bits (83), Expect = 0.090
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 692 TPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEK 751
T ++AV +R+ YC GS G MK R L +G+ V+ ++ WE + K +
Sbjct: 629 TDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWE---MDKLEMEDA 685
Query: 752 LAFLHEKVFT 761
+ FL K+++
Sbjct: 686 VTFLKTKIYS 695
>gi|45267832 FAST kinase domains 2 [Homo sapiens]
Length = 710
Score = 57.4 bits (137), Expect = 5e-08
Identities = 86/435 (19%), Positives = 182/435 (41%), Gaps = 44/435 (10%)
Query: 180 VLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVILGIPHS----HSMLDVYETKC--C 233
++ +F LC+ +++ ++ + L+ L A V LGIP + ++L V + + C
Sbjct: 206 LMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVTQERINEC 265
Query: 234 HQVWEMNMDQLLLVADLWRYLGRKVPRFLNIFSSYLNLHWKDLSLSQLVHLIYVIGENRQ 293
++ + +L + + + F + + WK + L ++ IG++
Sbjct: 266 DEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQV---WKIEDVFTLQVVMKCIGKDAP 322
Query: 294 VSQDLMQKLESLILKYID---LINLEEVGTICLGFFKSSTNLSEFVMRKIGDLACANIQH 350
++ L +KLE L+ +D ++N + + + S L + + + D NI
Sbjct: 323 IA--LKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLD----NIHG 376
Query: 351 LSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGVMHLTLYCSALRFLNEGV 410
R ++NI++ + +++ K + + + V+ + + L F G+
Sbjct: 377 CPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGL 436
Query: 411 MNAVAASLPPRVAHCRSKDVAKILWSFGTLN--YKPPNAEEFYSSLISEIHRKMPEFNQY 468
M+ + K++ IL ++ +LN YK N E+F + S + + +
Sbjct: 437 MDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISS- 495
Query: 469 PEHLPTCLLGLAFLEYFPVELIDFALSPGFVRLAQERTKFDLLKELYTLDGTVGIECPDY 528
E+L + + YFP L+P F +L Q+ D++ EL T D Y
Sbjct: 496 -ENLLDAVYSFCLMNYFP-------LAP-FNQLLQK----DIISELLTSDDMKNA----Y 538
Query: 529 RGNRLSTHLQQEGSELLWYLA------EKDMNSKPEFLETVFLLETMLGGPQYVKHHMIL 582
+ + L T L+ + + L +A +++ S + +L ++LGG + + L
Sbjct: 539 KLHTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHL 598
Query: 583 PHTRSSDLEVQLDVN 597
PH D E+++D N
Sbjct: 599 PHNYHIDFEIRMDTN 613
Score = 36.6 bits (83), Expect = 0.090
Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 692 TPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEK 751
T ++AV +R+ YC GS G MK R L +G+ V+ ++ WE + K +
Sbjct: 629 TDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWE---MDKLEMEDA 685
Query: 752 LAFLHEKVFT 761
+ FL K+++
Sbjct: 686 VTFLKTKIYS 695
>gi|40217812 cell cycle progression 2 protein isoform 1 [Homo
sapiens]
Length = 631
Score = 50.8 bits (120), Expect = 5e-06
Identities = 88/459 (19%), Positives = 178/459 (38%), Gaps = 17/459 (3%)
Query: 156 NNLQAQVIVDYLCKLSSLPAEQHPVLLGSTSFALLCQLSVKKIQLFDTQDLINVLKAFVI 215
+N A V++ LS P ++ ++ + LLC L+ + ++ L +L +
Sbjct: 97 SNQAAMVLIRLSHLLSEKPEDKGLLIQDAHFHQLLCLLNSQIASVWHGT-LSKLLGSLYA 155
Query: 216 LGIPHSHSMLDVYETKCCHQVWEMNMDQLLLVADLWRYLGRKV--PRFLNIFSSYLNLHW 273
LGIP + L E + ++ ++ L +A+ L ++ L ++L W
Sbjct: 156 LGIPKASKELQSVEQEVRWRMRKLKYKHLAFLAESCATLSQEQHSQELLAELLTHLERRW 215
Query: 274 KDLSLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSSTNLS 333
++ S L+ V+ + +S+ LM +LE L+ ++ E+ + L + + S
Sbjct: 216 TEIEDSHT--LVTVMMKVGHLSEPLMNRLEDKCLELVEHFGPNELRKV-LVMLAAQSRRS 272
Query: 334 EFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLGVQGV 393
++R I L+ L+++ + +++ +PSL V
Sbjct: 273 VPLLRAISYHLVQKPFSLTKDVLLDVAYAYGKLSFHQTQVSQRLATDLLSLMPSLTSGEV 332
Query: 394 MHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEEFYSS 453
H + L++L+ + A A + R + +L +F LN+ P ++F+S
Sbjct: 333 AHCAKSFALLKWLSLPLFEAFAQHVLNRAQDITLPHLCSVLLAFARLNFHPDQEDQFFSL 392
Query: 454 LISEIHRKMPEFNQYPEHLPTCLLGLAFLEYFPVELIDFALSPGF-VRLAQERTKFD--L 510
+ ++ ++P P + L L+ + L P F ++ +++ D
Sbjct: 393 VHEKLGSELPGLE--PALQVDLVWALCVLQQAREAELQAVLHPEFHIQFLGGKSQKDQNT 450
Query: 511 LKELYTLDGTVGIECPDYRGNRLSTHLQQEGSELLWYLAEKDMNSKPEFLETVFLLETML 570
++L ++ T +E P+Y G L G L D P E L+ +L
Sbjct: 451 FQKLLHINATALLEYPEYSGPLLPASAVAPGPSAL------DRKVTPLQKELQETLKGLL 504
Query: 571 GGPQYVKHHMILPHTRSSDLEVQLDVNLKPLPFNREATP 609
G + + D EV LD + + LP P
Sbjct: 505 GSADKGSLEVATQYGWVLDAEVLLDSDGEFLPVRDFVAP 543
Score = 37.0 bits (84), Expect = 0.069
Identities = 17/49 (34%), Positives = 32/49 (65%), Gaps = 2/49 (4%)
Query: 711 SRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKV 759
S+DLLG + RR + G+ +V++ ++EWL L ++ +K A+L +K+
Sbjct: 575 SKDLLGRFVLARRHIVAAGFLIVDVPFYEWLEL--KSEWQKGAYLKDKM 621
>gi|5729822 Fas-activated serine/threonine kinase isoform 1 [Homo
sapiens]
Length = 549
Score = 50.1 bits (118), Expect = 8e-06
Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 10/177 (5%)
Query: 364 RFTHVDHINFMKQIGEIAPQRI-PSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRV 422
RF + + + E P+ + P + V HL + R ++ A+A L +
Sbjct: 214 RFLRYPRQHLISSLAEARPEELTPHVMVLLAQHLARH----RLREPQLLEAIAHFLVVQE 269
Query: 423 AHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFL 482
SK V K++ FG LNY P E+ + + I + E P L+ L L
Sbjct: 270 TQLSSKVVQKLVLPFGRLNYLP--LEQQFMPCLERILAR--EAGVAPLATVNILMSLCQL 325
Query: 483 EYFPVELIDFALSPGFVRLAQERTKFDLLKE-LYTLDGTVGIECPDYRGNRLSTHLQ 538
P + F SPGF+ +++ L LD V +E P YRG RL Q
Sbjct: 326 RCLPFRALHFVFSPGFINYISGTPHALIVRRYLSLLDTAVELELPGYRGPRLPRRQQ 382
Score = 32.7 bits (73), Expect = 1.3
Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 687 AACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWE-----WL 741
+A + P ++ + R +C R LLG ++ R L +GY+++ L + E L
Sbjct: 467 SATTRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLPLPFEELESQRGL 526
Query: 742 PLLKRTRLEKLAFL 755
P LK +KL L
Sbjct: 527 PQLKSYLRQKLQAL 540
>gi|39995107 Fas-activated serine/threonine kinase isoform 4 [Homo
sapiens]
Length = 408
Score = 50.1 bits (118), Expect = 8e-06
Identities = 47/177 (26%), Positives = 71/177 (40%), Gaps = 10/177 (5%)
Query: 364 RFTHVDHINFMKQIGEIAPQRI-PSLGVQGVMHLTLYCSALRFLNEGVMNAVAASLPPRV 422
RF + + + E P+ + P + V HL + R ++ A+A L +
Sbjct: 73 RFLRYPRQHLISSLAEARPEELTPHVMVLLAQHLARH----RLREPQLLEAIAHFLVVQE 128
Query: 423 AHCRSKDVAKILWSFGTLNYKPPNAEEFYSSLISEIHRKMPEFNQYPEHLPTCLLGLAFL 482
SK V K++ FG LNY P E+ + + I + E P L+ L L
Sbjct: 129 TQLSSKVVQKLVLPFGRLNYLP--LEQQFMPCLERILAR--EAGVAPLATVNILMSLCQL 184
Query: 483 EYFPVELIDFALSPGFVRLAQERTKFDLLKE-LYTLDGTVGIECPDYRGNRLSTHLQ 538
P + F SPGF+ +++ L LD V +E P YRG RL Q
Sbjct: 185 RCLPFRALHFVFSPGFINYISGTPHALIVRRYLSLLDTAVELELPGYRGPRLPRRQQ 241
Score = 32.7 bits (73), Expect = 1.3
Identities = 21/74 (28%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 687 AACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWE-----WL 741
+A + P ++ + R +C R LLG ++ R L +GY+++ L + E L
Sbjct: 326 SATTRDPAQRVVLVLRERWHFCRDGRVLLGSRALRERHLGLMGYQLLPLPFEELESQRGL 385
Query: 742 PLLKRTRLEKLAFL 755
P LK +KL L
Sbjct: 386 PQLKSYLRQKLQAL 399
>gi|40217810 cell cycle progression 2 protein isoform 2 [Homo
sapiens]
Length = 521
Score = 37.0 bits (84), Expect = 0.069
Identities = 17/49 (34%), Positives = 32/49 (65%), Gaps = 2/49 (4%)
Query: 711 SRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKV 759
S+DLLG + RR + G+ +V++ ++EWL L ++ +K A+L +K+
Sbjct: 465 SKDLLGRFVLARRHIVAAGFLIVDVPFYEWLEL--KSEWQKGAYLKDKM 511
>gi|13569848 cell cycle progression 2 protein isoform 2 [Homo
sapiens]
Length = 521
Score = 37.0 bits (84), Expect = 0.069
Identities = 17/49 (34%), Positives = 32/49 (65%), Gaps = 2/49 (4%)
Query: 711 SRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLKRTRLEKLAFLHEKV 759
S+DLLG + RR + G+ +V++ ++EWL L ++ +K A+L +K+
Sbjct: 465 SKDLLGRFVLARRHIVAAGFLIVDVPFYEWLEL--KSEWQKGAYLKDKM 511
>gi|57242796 jumonji, AT rich interactive domain 1B [Homo sapiens]
Length = 1544
Score = 32.7 bits (73), Expect = 1.3
Identities = 18/73 (24%), Positives = 34/73 (46%), Gaps = 2/73 (2%)
Query: 686 PAACMQTPRMKLAVQFTNRNQYCYGSRDLLGLHNMKRRQLARLGYRVVELSYWEWLPLLK 745
P+ QT R + +N C G RD G+++++R+ RL + WE + ++
Sbjct: 1374 PSPAQQTDRSSPVRPSSEKNDCCRGKRD--GINSLERKLKRRLEREGLSSERWERVKKMR 1431
Query: 746 RTRLEKLAFLHEK 758
+ +K+ H K
Sbjct: 1432 TPKKKKIKLSHPK 1444
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 32.3 bits (72), Expect = 1.7
Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 46 HISLCHSAKKVKNICSTFSSRRILTTSSAHPGLEFSKTSSS---KASTLQLGSPRATGVD 102
H+S C S K NI S+RR + S+ P L T +S S +Q P + D
Sbjct: 3472 HLS-CFSMKSWPNILFQASARRAASPPSSPPSLSLPSTVTSSLCSTSGVQTSLPTESCSD 3530
Query: 103 EEDVEVFDSFENMRVFLQLR 122
E D E+ E++ L+++
Sbjct: 3531 ESDSELSQKLEDLDNSLEVK 3550
>gi|4505683 platelet-derived growth factor receptor beta precursor
[Homo sapiens]
Length = 1106
Score = 31.2 bits (69), Expect = 3.8
Identities = 25/82 (30%), Positives = 37/82 (45%), Gaps = 10/82 (12%)
Query: 510 LLKELYTLDGTVGIECPDY--------RGNRLS--THLQQEGSELLWYLAEKDMNSKPEF 559
LL E++TL GT E P RG R++ H E E++ E+ +P F
Sbjct: 892 LLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRPPF 951
Query: 560 LETVFLLETMLGGPQYVKHHMI 581
+ V LLE +LG K+ +
Sbjct: 952 SQLVLLLERLLGEGYKKKYQQV 973
>gi|4506671 ribosomal protein P2 [Homo sapiens]
Length = 115
Score = 30.8 bits (68), Expect = 4.9
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 7/82 (8%)
Query: 607 ATPAENVAKLRLEHVGVSLTDDLMNKLLKGKARGHFQGKTESEPGQQPMELENKAAVPLG 666
++P+ K L+ VG+ DD +NK++ GK + Q + A+VP G
Sbjct: 16 SSPSAKDIKKILDSVGIEADDDRLNKVI-----SELNGKNIEDVIAQ--GIGKLASVPAG 68
Query: 667 GFLCNVADKSGAMEMAGLCPAA 688
G + A A AG PAA
Sbjct: 69 GAVAVSAAPGSAAPAAGSAPAA 90
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 30.4 bits (67), Expect = 6.4
Identities = 35/161 (21%), Positives = 59/161 (36%), Gaps = 14/161 (8%)
Query: 71 TSSAHPGLEFSKTSSSKASTLQL------GSPRATGVDEEDVEVFDSFENMRVFLQLRPE 124
T SA + + T AS + SP + D+ ++Q+ +
Sbjct: 170 TVSAKYAMRYFATVGGSASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFD 229
Query: 125 YRVHSYNASETSQLLSVSEGELILHKVRVNQNNLQAQVIVDYLCKLSSLPAEQHPVLLGS 184
R H A+ + LL S +V ++ + I LC + LP + L +
Sbjct: 230 KRYHIIGANMRTYLLEKS-------RVVFQADDERNYHIFYQLCAAAGLPEFKELALTSA 282
Query: 185 TSFALLCQLSVKKIQ-LFDTQDLINVLKAFVILGIPHSHSM 224
F Q I+ + D +D +AF +LG+ SH M
Sbjct: 283 EDFFYTSQGGDTSIEGVDDAEDFEKTRQAFTLLGVKESHQM 323
>gi|46195755 SCAN domain containing 3 [Homo sapiens]
Length = 1325
Score = 30.0 bits (66), Expect = 8.4
Identities = 46/206 (22%), Positives = 83/206 (40%), Gaps = 41/206 (19%)
Query: 271 LHWKDL-SLSQLVHLIYVIGENRQVSQDLMQKLESLILKYIDLINLEEVGTICLGFFKSS 329
LH +DL + HL G ++ ++L K ++ I K + ++ L T+C + +
Sbjct: 302 LHSEDLFDILHNTHLSIGHGGRTRMEKELQAKYKN-ITKEVIMLYL----TLCKPCQQKN 356
Query: 330 TNLSEFVMRKIGDLACANIQHLSSRSLVNIVKMFRFTHVDHINFMKQIGEIAPQRIPSLG 389
+ L + + K +I+ +SSR V+++ M Q P
Sbjct: 357 SKLKKVLTSK-------SIKEVSSRCQVDLIDM--------------------QLNPDGE 389
Query: 390 VQGVMHLTLYCSALRFLNEGVMNAVAASLPPRVAHCRSKDVAKILWSFGTLNYKPPNAEE 449
+ ++H C+ L FL ++ + P VAH D+ I+ + L + N E
Sbjct: 390 YRFILHYQDLCTKLTFLR-----SLKSKRPTEVAHALL-DIFTIIGAPSVL--QSDNGRE 441
Query: 450 FYSSLISEIHRKMPEFNQYPEHLPTC 475
F S ++SE+ PE TC
Sbjct: 442 FSSQVVSELSNIWPELKIVHGKSQTC 467
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,108,223
Number of Sequences: 37866
Number of extensions: 1220958
Number of successful extensions: 2862
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 2821
Number of HSP's gapped (non-prelim): 34
length of query: 764
length of database: 18,247,518
effective HSP length: 110
effective length of query: 654
effective length of database: 14,082,258
effective search space: 9209796732
effective search space used: 9209796732
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.